SETD5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This function of this gene has yet to be determined but mutations in this gene have been associated with autosomal dominant mental retardation-23. Alternative splicing results in multiple transcript variants encoding different isoforms. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pre-miRNA processing (GO:0031054)5.35418784
2nuclear pore complex assembly (GO:0051292)4.87430129
3mitotic sister chromatid cohesion (GO:0007064)4.84789190
4nuclear pore organization (GO:0006999)4.44874097
5positive regulation of hormone biosynthetic process (GO:0046886)4.15337920
6cytoplasmic mRNA processing body assembly (GO:0033962)4.05009161
7regulation of histone H3-K4 methylation (GO:0051569)3.97869930
8glucocorticoid receptor signaling pathway (GO:0042921)3.68813732
9regulation of RNA export from nucleus (GO:0046831)3.66718031
10NLS-bearing protein import into nucleus (GO:0006607)3.60994939
11paraxial mesoderm development (GO:0048339)3.59631873
12regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.57537801
13pore complex assembly (GO:0046931)3.57021095
14negative regulation of histone methylation (GO:0031061)3.48704380
15nucleosome disassembly (GO:0006337)3.47349137
16protein-DNA complex disassembly (GO:0032986)3.47349137
17hippo signaling (GO:0035329)3.36139088
18regulation of histone methylation (GO:0031060)3.26168747
19positive regulation of hormone metabolic process (GO:0032352)3.25671001
20regulation of NFAT protein import into nucleus (GO:0051532)3.20290348
21regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.17479042
22peptidyl-lysine dimethylation (GO:0018027)3.17253799
23protein dealkylation (GO:0008214)3.15807503
24protein demethylation (GO:0006482)3.15807503
25insulin-like growth factor receptor signaling pathway (GO:0048009)3.14950383
26planar cell polarity pathway involved in neural tube closure (GO:0090179)3.08830456
27corticosteroid receptor signaling pathway (GO:0031958)3.06193338
28mating behavior (GO:0007617)3.05389591
29notochord development (GO:0030903)3.03943533
30regulation of sister chromatid cohesion (GO:0007063)3.02469039
31negative regulation of DNA repair (GO:0045738)2.99207140
32regulation of nucleobase-containing compound transport (GO:0032239)2.97406111
33histone H3-K4 methylation (GO:0051568)2.92344723
34positive regulation of protein import into nucleus, translocation (GO:0033160)2.91396351
35negative regulation of translation, ncRNA-mediated (GO:0040033)2.90929415
36regulation of translation, ncRNA-mediated (GO:0045974)2.90929415
37negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.90929415
38histone H3-K4 trimethylation (GO:0080182)2.89482692
39RNA stabilization (GO:0043489)2.89264383
40mRNA stabilization (GO:0048255)2.89264383
41positive regulation of SMAD protein import into nucleus (GO:0060391)2.88886628
42dosage compensation (GO:0007549)2.88116374
43heterochromatin organization (GO:0070828)2.88078121
44regulation of DNA endoreduplication (GO:0032875)2.83814759
45protein localization to microtubule (GO:0035372)2.83299726
46histone H3-K36 demethylation (GO:0070544)2.83128021
47regulation of histone H3-K27 methylation (GO:0061085)2.81375906
48regulation of histone H3-K9 methylation (GO:0051570)2.79558796
49stress granule assembly (GO:0034063)2.77887031
50heart morphogenesis (GO:0003007)2.74853784
51regulation of intracellular estrogen receptor signaling pathway (GO:0033146)2.73899192
52establishment of spindle orientation (GO:0051294)2.71576112
53positive regulation of catenin import into nucleus (GO:0035413)2.71437735
54establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197)2.70514997
55regulation of translational fidelity (GO:0006450)2.70015254
56histone H3-K9 demethylation (GO:0033169)2.68723348
57gastrulation with mouth forming second (GO:0001702)2.67623226
58histone lysine methylation (GO:0034968)2.67351288
59head development (GO:0060322)2.66654404
60histone H3-K9 methylation (GO:0051567)2.63655612
61dorsal/ventral axis specification (GO:0009950)2.63338518
62negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.63234444
63peptidyl-lysine trimethylation (GO:0018023)2.61208657
64polarized epithelial cell differentiation (GO:0030859)2.59599817
65positive regulation of mitotic sister chromatid separation (GO:1901970)2.59475648
66positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.59475648
67positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.59475648
68mitotic sister chromatid segregation (GO:0000070)2.57546797
69positive regulation of histone deacetylation (GO:0031065)2.57455491
70establishment of spindle localization (GO:0051293)2.54860716
71sister chromatid segregation (GO:0000819)2.54817100
72mitotic nuclear envelope disassembly (GO:0007077)2.54359098
73mitotic chromosome condensation (GO:0007076)2.52189649
74regulation of posttranscriptional gene silencing (GO:0060147)2.50324004
75regulation of gene silencing by miRNA (GO:0060964)2.50324004
76regulation of gene silencing by RNA (GO:0060966)2.50324004
77apical protein localization (GO:0045176)2.49002187
78camera-type eye morphogenesis (GO:0048593)2.48759601
79DNA unwinding involved in DNA replication (GO:0006268)2.48272769
80regulation of SMAD protein import into nucleus (GO:0060390)2.48160375
81nuclear envelope disassembly (GO:0051081)2.47970390
82membrane disassembly (GO:0030397)2.47970390
83DNA geometric change (GO:0032392)2.47954712
84DNA duplex unwinding (GO:0032508)2.47541979
85neural tube development (GO:0021915)2.47346018
86chromatin assembly (GO:0031497)2.46271334
87histone H2A monoubiquitination (GO:0035518)2.46061787
88neural tube closure (GO:0001843)2.45998949
89protein localization to kinetochore (GO:0034501)2.45604318
90histone lysine demethylation (GO:0070076)2.45336812
91histone H4-K16 acetylation (GO:0043984)2.45182289
92adherens junction assembly (GO:0034333)2.44939609
93embryonic eye morphogenesis (GO:0048048)2.44487094
94negative regulation of chromatin modification (GO:1903309)2.44023203
95embryonic retina morphogenesis in camera-type eye (GO:0060059)2.43474523
96tube closure (GO:0060606)2.42336217
97establishment of apical/basal cell polarity (GO:0035089)2.42148936
98gene silencing by RNA (GO:0031047)2.42010769
99positive regulation of megakaryocyte differentiation (GO:0045654)2.41192246
100regulation of protein polyubiquitination (GO:1902914)2.41006640
101histone H3-K9 modification (GO:0061647)2.39652290
102positive regulation of transcription from RNA polymerase III promoter (GO:0045945)2.39616144
103DNA topological change (GO:0006265)2.39013024
104regulation of establishment of planar polarity (GO:0090175)2.38938944
105negative regulation of mRNA metabolic process (GO:1903312)2.38863219
106establishment of mitotic spindle localization (GO:0040001)2.38839692
107positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145)2.38705268
108regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)2.38206541
109positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)2.38206541
110positive regulation by host of viral transcription (GO:0043923)2.38027620
111semaphorin-plexin signaling pathway (GO:0071526)2.36422233
112negative regulation of histone modification (GO:0031057)2.34809918
113regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:00432.34648149
114histone mRNA catabolic process (GO:0071044)2.34288843
115alternative mRNA splicing, via spliceosome (GO:0000380)2.33699295
116histone methylation (GO:0016571)2.33472007
117interkinetic nuclear migration (GO:0022027)2.33020739
118histone demethylation (GO:0016577)2.32865532
119embryonic foregut morphogenesis (GO:0048617)2.32803822
120negative regulation of RNA splicing (GO:0033119)2.32623217
121peripheral nervous system axon ensheathment (GO:0032292)2.31960207
122myelination in peripheral nervous system (GO:0022011)2.31960207
123positive regulation of cell cycle G2/M phase transition (GO:1902751)2.31904399
124positive regulation of G2/M transition of mitotic cell cycle (GO:0010971)2.31904399
125eye morphogenesis (GO:0048592)2.31612315
126regulation of mitotic spindle organization (GO:0060236)2.31371855
127establishment of mitotic spindle orientation (GO:0000132)2.31164350
128regulation of stem cell maintenance (GO:2000036)2.30438872
129gene silencing (GO:0016458)2.30380554
130Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.30258412
131regulation of centriole replication (GO:0046599)2.30157249
132coronary vasculature morphogenesis (GO:0060977)2.28891613
133embryonic camera-type eye morphogenesis (GO:0048596)2.28491872
134regulation of catenin import into nucleus (GO:0035412)2.28404595
135convergent extension (GO:0060026)2.27450064
136negative regulation of mRNA processing (GO:0050686)2.27358085
137positive regulation of gene expression, epigenetic (GO:0045815)2.27011017
138peptidyl-lysine methylation (GO:0018022)2.26923915
139forebrain development (GO:0030900)2.26815400
140anterior/posterior axis specification, embryo (GO:0008595)2.26686592
141establishment of nucleus localization (GO:0040023)2.24035074

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.69617043
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.65636050
3EGR1_19374776_ChIP-ChIP_THP-1_Human4.63608306
4NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.82696632
5SALL1_21062744_ChIP-ChIP_HESCs_Human3.66976446
6* KDM5B_21448134_ChIP-Seq_MESCs_Mouse3.03520930
7TP63_19390658_ChIP-ChIP_HaCaT_Human2.59644481
8MYC_22102868_ChIP-Seq_BL_Human2.54501001
9E2F4_17652178_ChIP-ChIP_JURKAT_Human2.40575281
10ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.40023254
11DMRT1_23473982_ChIP-Seq_TESTES_Mouse2.23905111
12SMAD3_22036565_ChIP-Seq_ESCs_Mouse2.19759370
13FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.17548302
14* TCF3_18467660_ChIP-ChIP_MESCs_Mouse2.08999542
15HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse2.07806078
16RBPJ_22232070_ChIP-Seq_NCS_Mouse2.02663950
17FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human2.00051617
18* SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.99971321
19ZFP281_27345836_Chip-Seq_ESCs_Mouse1.96330651
20NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.93199364
21STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.89503866
22* ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.87482062
23* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.84690387
24TCF7_22412390_ChIP-Seq_EML_Mouse1.81485791
25TP63_17297297_ChIP-ChIP_HaCaT_Human1.76373416
26FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.75416190
27KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.75142980
28ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.74924886
29PKCTHETA_26484144_Chip-Seq_BREAST_Human1.74588199
30STAT6_21828071_ChIP-Seq_BEAS2B_Human1.74171555
31STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.70437347
32* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.69341202
33KDM2B_26808549_Chip-Seq_DND41_Human1.67078818
34HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.66611880
35E2F1_21310950_ChIP-Seq_MCF-7_Human1.66387004
36GATA1_26923725_Chip-Seq_HPCs_Mouse1.64250171
37GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.64184696
38ISL1_27105846_Chip-Seq_CPCs_Mouse1.63216849
39* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.60781014
40AR_21572438_ChIP-Seq_LNCaP_Human1.58408945
41MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.57166237
42EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.52953054
43KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.48183805
44BRD4_25478319_ChIP-Seq_HGPS_Human1.43320199
45RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.42115943
46KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.39483615
47KDM2B_26808549_Chip-Seq_JURKAT_Human1.37416960
48HIF1A_21447827_ChIP-Seq_MCF-7_Human1.36963964
49ESR1_21235772_ChIP-Seq_MCF-7_Human1.36918572
50* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.36661567
51* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.36598542
52ESR2_21235772_ChIP-Seq_MCF-7_Human1.34829095
53P300_27058665_Chip-Seq_ZR-75-30cells_Human1.34603255
54NFIB_24661679_ChIP-Seq_LUNG_Mouse1.34215535
55CIITA_25753668_ChIP-Seq_RAJI_Human1.34121331
56KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.32448979
57KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.32448979
58KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.32448979
59CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.30670612
60KDM2B_26808549_Chip-Seq_SUP-B15_Human1.30208648
61AR_21909140_ChIP-Seq_LNCAP_Human1.28788067
62TBX3_20139965_ChIP-Seq_ESCs_Mouse1.28468564
63SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.28323551
64TBX3_20139965_ChIP-Seq_MESCs_Mouse1.27452132
65ZNF217_24962896_ChIP-Seq_MCF-7_Human1.23851355
66* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.23581674
67NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.22883802
68RING1B_27294783_Chip-Seq_NPCs_Mouse1.22074286
69PRDM14_21183938_ChIP-Seq_MESCs_Mouse1.22057533
70CHD1_26751641_Chip-Seq_LNCaP_Human1.20816639
71KDM2B_26808549_Chip-Seq_K562_Human1.15319924
72ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.14819173
73* FOXA2_19822575_ChIP-Seq_HepG2_Human1.13312985
74VDR_21846776_ChIP-Seq_THP-1_Human1.13309238
75PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.13289873
76CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.13045846
77TP53_16413492_ChIP-PET_HCT116_Human1.12644462
78STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.11509031
79KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.08738166
80ESR1_15608294_ChIP-ChIP_MCF-7_Human1.08653384
81FOXO3_23340844_ChIP-Seq_DLD1_Human1.08390889
82CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.08147503
83NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.06870409
84RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.05440939
85WT1_19549856_ChIP-ChIP_CCG9911_Human1.04250118
86ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.03603581
87ESR1_20079471_ChIP-ChIP_T-47D_Human1.02762574
88ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.02654411
89* POU5F1_18347094_ChIP-ChIP_MESCs_Mouse1.02051839
90* TCF4_18268006_ChIP-ChIP_LS174T_Human1.02050123
91BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.01635426
92* CTNNB1_20460455_ChIP-Seq_HCT116_Human1.00105765
93NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.98709553
94TCF3_18692474_ChIP-Seq_MESCs_Mouse0.98508816
95RARB_27405468_Chip-Seq_BRAIN_Mouse0.98288695
96* CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97990570
97SOX9_26525672_Chip-Seq_HEART_Mouse0.97576366
98TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.97392138
99AR_19668381_ChIP-Seq_PC3_Human0.97388500
100SMAD_19615063_ChIP-ChIP_OVARY_Human0.97238298
101RUNX1_27514584_Chip-Seq_MCF-7_Human0.97210988
102* OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.96678303
103YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.96301970
104YAP1_20516196_ChIP-Seq_MESCs_Mouse0.96173076
105* NANOG_21062744_ChIP-ChIP_HESCs_Human0.96155049
106SOX9_24532713_ChIP-Seq_HFSC_Mouse0.95615180
107CLOCK_20551151_ChIP-Seq_293T_Human0.95506358
108CREB1_26743006_Chip-Seq_LNCaP_Human0.95087943
109DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.94614128
110AHR_22903824_ChIP-Seq_MCF-7_Human0.93429564
111ARNT_22903824_ChIP-Seq_MCF-7_Human0.92751513
112TCF3_18347094_ChIP-ChIP_MESCs_Mouse0.92685922
113EZH2_18974828_ChIP-Seq_MESCs_Mouse0.92418911
114RNF2_18974828_ChIP-Seq_MESCs_Mouse0.92418911
115ERG_21242973_ChIP-ChIP_JURKAT_Human0.92301660
116NCOR1_26117541_ChIP-Seq_K562_Human0.91815405
117WT1_25993318_ChIP-Seq_PODOCYTE_Human0.90934391
118ELK3_25401928_ChIP-Seq_HUVEC_Human0.90732490
119VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.89333911
120* GATA6_25053715_ChIP-Seq_YYC3_Human0.88423896
121POU5F1_16518401_ChIP-PET_MESCs_Mouse0.88384109
122SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.88074047
123UBF1/2_26484160_Chip-Seq_HMECs_Human0.87637246
124FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.87077353
125STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.83834297
126UTX_26944678_Chip-Seq_JUKART_Human0.83415449
127TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.82824192
128NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.82694327

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation4.09686057
2MP0005076_abnormal_cell_differentiation3.04263213
3MP0003705_abnormal_hypodermis_morpholog2.83963087
4MP0010352_gastrointestinal_tract_polyps2.62507088
5MP0003121_genomic_imprinting2.52774589
6MP0003122_maternal_imprinting2.42880881
7MP0005409_darkened_coat_color2.29446429
8MP0003123_paternal_imprinting2.08761545
9MP0010030_abnormal_orbit_morphology2.05114724
10MP0003890_abnormal_embryonic-extraembry1.98876778
11MP0000566_synostosis1.95839642
12MP0000537_abnormal_urethra_morphology1.95377370
13MP0004197_abnormal_fetal_growth/weight/1.92589874
14MP0001346_abnormal_lacrimal_gland1.86367575
15MP0009053_abnormal_anal_canal1.80773315
16MP0010307_abnormal_tumor_latency1.77693524
17MP0000733_abnormal_muscle_development1.73893479
18MP0003787_abnormal_imprinting1.72702446
19MP0008057_abnormal_DNA_replication1.72170792
20MP0002084_abnormal_developmental_patter1.72119364
21MP0003935_abnormal_craniofacial_develop1.67468805
22MP0003283_abnormal_digestive_organ1.66947818
23MP0001293_anophthalmia1.65226810
24MP0000428_abnormal_craniofacial_morphol1.61344586
25MP0010234_abnormal_vibrissa_follicle1.61270973
26MP0010094_abnormal_chromosome_stability1.56892276
27MP0003385_abnormal_body_wall1.54480730
28MP0003567_abnormal_fetal_cardiomyocyte1.53504247
29MP0005380_embryogenesis_phenotype1.53456473
30MP0001672_abnormal_embryogenesis/_devel1.53456473
31MP0003693_abnormal_embryo_hatching1.53398067
32MP0002088_abnormal_embryonic_growth/wei1.53378584
33MP0003984_embryonic_growth_retardation1.53209450
34MP0005503_abnormal_tendon_morphology1.52996888
35MP0009703_decreased_birth_body1.52474451
36MP0003111_abnormal_nucleus_morphology1.51990272
37MP0002249_abnormal_larynx_morphology1.50739907
38MP0004264_abnormal_extraembryonic_tissu1.50655808
39MP0003300_gastrointestinal_ulcer1.49964315
40MP0002086_abnormal_extraembryonic_tissu1.49681048
41MP0002085_abnormal_embryonic_tissue1.47880395
42MP0000778_abnormal_nervous_system1.47470045
43MP0003115_abnormal_respiratory_system1.46438447
44MP0004858_abnormal_nervous_system1.44789516
45MP0003566_abnormal_cell_adhesion1.44733883
46MP0003937_abnormal_limbs/digits/tail_de1.44621521
47MP0003077_abnormal_cell_cycle1.38511482
48MP0004272_abnormal_basement_membrane1.38090078
49MP0005187_abnormal_penis_morphology1.37773013
50MP0009278_abnormal_bone_marrow1.37243849
51MP0002089_abnormal_postnatal_growth/wei1.37218058
52MP0000432_abnormal_head_morphology1.37014393
53MP0001299_abnormal_eye_distance/1.36941285
54MP0000350_abnormal_cell_proliferation1.36585978
55MP0003119_abnormal_digestive_system1.36280765
56MP0001730_embryonic_growth_arrest1.34105393
57MP0008438_abnormal_cutaneous_collagen1.33625949
58MP0002925_abnormal_cardiovascular_devel1.31109088
59MP0008877_abnormal_DNA_methylation1.29587059
60MP0005623_abnormal_meninges_morphology1.29482730
61MP0001849_ear_inflammation1.29254073
62MP0001697_abnormal_embryo_size1.28258866
63MP0003941_abnormal_skin_development1.28028991
64MP0005248_abnormal_Harderian_gland1.26365748
65MP0008932_abnormal_embryonic_tissue1.25055793
66MP0004808_abnormal_hematopoietic_stem1.24722625
67MP0003755_abnormal_palate_morphology1.22723395
68MP0009672_abnormal_birth_weight1.22711197
69MP0002877_abnormal_melanocyte_morpholog1.22275886
70MP0003942_abnormal_urinary_system1.20345611
71MP0002938_white_spotting1.18569637
72MP0002697_abnormal_eye_size1.18220676
73MP0003938_abnormal_ear_development1.17787031
74MP0003943_abnormal_hepatobiliary_system1.17624298
75MP0005367_renal/urinary_system_phenotyp1.17027583
76MP0000516_abnormal_urinary_system1.17027583
77MP0004233_abnormal_muscle_weight1.15650775
78MP0003045_fibrosis1.14669643
79MP0000534_abnormal_ureter_morphology1.14304425
80MP0002081_perinatal_lethality1.13588181
81MP0010678_abnormal_skin_adnexa1.10637252
82MP0003091_abnormal_cell_migration1.10354888
83MP0000579_abnormal_nail_morphology1.10347213
84MP0002116_abnormal_craniofacial_bone1.10326674
85MP0002092_abnormal_eye_morphology1.08978213
86MP0000631_abnormal_neuroendocrine_gland1.04933996
87MP0003136_yellow_coat_color1.04135933
88MP0009780_abnormal_chondrocyte_physiolo1.03774914
89MP0002932_abnormal_joint_morphology1.03721042
90MP0000383_abnormal_hair_follicle1.03417973
91MP0004957_abnormal_blastocyst_morpholog1.03343691
92MP0002152_abnormal_brain_morphology1.02485254
93MP0000955_abnormal_spinal_cord1.01891456
94MP0001915_intracranial_hemorrhage0.99481771
95MP0008961_abnormal_basal_metabolism0.99014442
96MP0002396_abnormal_hematopoietic_system0.98427844
97MP0001177_atelectasis0.98151675
98MP0002080_prenatal_lethality0.98126616
99MP0002109_abnormal_limb_morphology0.98084496
100MP0006054_spinal_hemorrhage0.95541902
101MP0004185_abnormal_adipocyte_glucose0.94494790
102MP0000049_abnormal_middle_ear0.94457988
103MP0005275_abnormal_skin_tensile0.93389443
104MP0000266_abnormal_heart_morphology0.93160321
105MP0002111_abnormal_tail_morphology0.92776293
106MP0010630_abnormal_cardiac_muscle0.91590308
107MP0002896_abnormal_bone_mineralization0.89940155
108MP0005023_abnormal_wound_healing0.89724721
109MP0004859_abnormal_synaptic_plasticity0.89700920
110MP0009250_abnormal_appendicular_skeleto0.89539320
111MP0003861_abnormal_nervous_system0.89269074
112MP0008007_abnormal_cellular_replicative0.89218811
113MP0001286_abnormal_eye_development0.87578110
114MP0005257_abnormal_intraocular_pressure0.87184281
115MP0005508_abnormal_skeleton_morphology0.86395556
116MP0002114_abnormal_axial_skeleton0.85759568
117MP0000003_abnormal_adipose_tissue0.85665227
118MP0006138_congestive_heart_failure0.84961444
119MP0005083_abnormal_biliary_tract0.84871002
120MP0000462_abnormal_digestive_system0.84810982
121MP0000371_diluted_coat_color0.84550157
122MP0002009_preneoplasia0.83263807
123MP0002108_abnormal_muscle_morphology0.83111121
124MP0002233_abnormal_nose_morphology0.82884363
125MP0001784_abnormal_fluid_regulation0.81852786
126MP0000762_abnormal_tongue_morphology0.78966618
127MP0000377_abnormal_hair_follicle0.75866245

Predicted human phenotypes

RankGene SetZ-score
1Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)4.00183584
2Short 4th metacarpal (HP:0010044)4.00183584
3Cortical dysplasia (HP:0002539)3.39809111
4Volvulus (HP:0002580)3.14749758
5Macroorchidism (HP:0000053)2.98754457
6Abnormality of the 4th metacarpal (HP:0010012)2.96883627
7Abnormality of the fingertips (HP:0001211)2.95246994
8Shallow orbits (HP:0000586)2.83688746
9High anterior hairline (HP:0009890)2.77615404
10Long eyelashes (HP:0000527)2.74491693
11Trigonocephaly (HP:0000243)2.66683202
12Renal duplication (HP:0000075)2.61477588
13Broad thumb (HP:0011304)2.53521106
14Increased nuchal translucency (HP:0010880)2.51613246
15Narrow palate (HP:0000189)2.49615946
16Urethral obstruction (HP:0000796)2.47658662
17Cerebral aneurysm (HP:0004944)2.45983119
18Hyperacusis (HP:0010780)2.45492900
19Midline defect of the nose (HP:0004122)2.39367187
20Astrocytoma (HP:0009592)2.35443082
21Abnormality of the astrocytes (HP:0100707)2.35443082
22Vertebral arch anomaly (HP:0008438)2.34373057
23Renovascular hypertension (HP:0100817)2.32246063
24Hypoplastic ischia (HP:0003175)2.30670671
25Supernumerary ribs (HP:0005815)2.25386732
26Ependymoma (HP:0002888)2.17945635
27Obstructive sleep apnea (HP:0002870)2.17614963
28Aplasia/Hypoplasia of the sternum (HP:0006714)2.16197462
29Neoplasm of the oral cavity (HP:0100649)2.14227527
30Glioma (HP:0009733)2.13832505
31Abnormality of the nasal septum (HP:0000419)2.12698261
32Absent frontal sinuses (HP:0002688)2.11461157
33Hypoplastic labia majora (HP:0000059)2.10843002
34Elfin facies (HP:0004428)2.07532774
35Subacute progressive viral hepatitis (HP:0006572)2.07156228
36Skull defect (HP:0001362)2.06547259
37Heterotopia (HP:0002282)2.06157491
38Broad phalanges of the hand (HP:0009768)2.05414399
39Deviation of the thumb (HP:0009603)2.03334463
40Arterial tortuosity (HP:0005116)2.02893083
41Deep philtrum (HP:0002002)2.02316180
42Anal stenosis (HP:0002025)2.02275005
43Bronchomalacia (HP:0002780)2.00185070
44Broad palm (HP:0001169)1.99593170
45Aortic aneurysm (HP:0004942)1.98594177
46Chin dimple (HP:0010751)1.98173099
47Cutaneous finger syndactyly (HP:0010554)1.97342937
48Abnormality of the ischium (HP:0003174)1.95819389
49Abnormality of the aortic arch (HP:0012303)1.95564741
50Cutaneous syndactyly (HP:0012725)1.95478230
51Proximal placement of thumb (HP:0009623)1.93827401
52Gastrointestinal carcinoma (HP:0002672)1.93402925
53Malignant gastrointestinal tract tumors (HP:0006749)1.93402925
54Broad finger (HP:0001500)1.93333641
55Medulloblastoma (HP:0002885)1.93327631
56Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.93307003
57Abnormality of the distal phalanx of the thumb (HP:0009617)1.93249116
58Hypoplasia of the maxilla (HP:0000327)1.91674991
59Chromosomal breakage induced by crosslinking agents (HP:0003221)1.90545164
60Mitral valve prolapse (HP:0001634)1.89818621
61Deep palmar crease (HP:0006191)1.89793593
62Truncal obesity (HP:0001956)1.89573119
63Limited elbow extension (HP:0001377)1.89116591
64Broad phalanx (HP:0006009)1.88840881
65Bowel diverticulosis (HP:0005222)1.88012816
66Spina bifida occulta (HP:0003298)1.87308906
67Overlapping toe (HP:0001845)1.86596303
68Abnormality of the labia majora (HP:0012881)1.86256634
69Disproportionate tall stature (HP:0001519)1.85891427
70Overgrowth (HP:0001548)1.84263407
71Protrusio acetabuli (HP:0003179)1.83851213
72Supernumerary bones of the axial skeleton (HP:0009144)1.83686249
73* Obsessive-compulsive behavior (HP:0000722)1.83117230
74Sandal gap (HP:0001852)1.82804323
75Broad long bones (HP:0005622)1.81476659
76Spinal cord lesions (HP:0100561)1.80996267
77Syringomyelia (HP:0003396)1.80996267
78Skin tags (HP:0010609)1.80927124
79Chromsome breakage (HP:0040012)1.80822205
80Rectal prolapse (HP:0002035)1.80630378
81Overriding aorta (HP:0002623)1.80330198
82Abnormality of the diencephalon (HP:0010662)1.79673353
83Smooth philtrum (HP:0000319)1.79040691
84Prominent nose (HP:0000448)1.78892791
85Flat acetabular roof (HP:0003180)1.75018006
86Ectopic kidney (HP:0000086)1.74781682
87Duplication of thumb phalanx (HP:0009942)1.74199911
88Transitional cell carcinoma of the bladder (HP:0006740)1.73840409
89Ankle contracture (HP:0006466)1.73558016
90Bladder diverticulum (HP:0000015)1.73147658
91Wide anterior fontanel (HP:0000260)1.72909217
92Vascular tortuosity (HP:0004948)1.72778770
93Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.72558525
94Enlarged penis (HP:0000040)1.72511002
95Low anterior hairline (HP:0000294)1.72417158
96Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.71964586
97Abnormality of incisor morphology (HP:0011063)1.70979914
98Neoplasm of the heart (HP:0100544)1.70858494
99Dislocated radial head (HP:0003083)1.70825862
100Thick eyebrow (HP:0000574)1.70537380
101Abnormal number of incisors (HP:0011064)1.70299972
102Uterine leiomyosarcoma (HP:0002891)1.70277606
103Leiomyosarcoma (HP:0100243)1.70277606
104Dysmetric saccades (HP:0000641)1.70229159
105Deviation of the hallux (HP:0010051)1.69344509
106Abnormality of the parietal bone (HP:0002696)1.68979454
107Vitreoretinal degeneration (HP:0000655)1.68847772
108Aneurysm (HP:0002617)1.68640704
109Flat cornea (HP:0007720)1.68328520
110Hepatoblastoma (HP:0002884)1.68295434
111Colon cancer (HP:0003003)1.67786230
112Arnold-Chiari malformation (HP:0002308)1.67188468
113Pointed chin (HP:0000307)1.67011640
114Exostoses (HP:0100777)1.66105755
115Aqueductal stenosis (HP:0002410)1.65390679
116Neoplasm of striated muscle (HP:0009728)1.65158300
117Neonatal short-limb short stature (HP:0008921)1.65054440
118Asymmetry of the thorax (HP:0001555)1.64080234
119Thin ribs (HP:0000883)1.64073281
120Abnormality of the radial head (HP:0003995)1.64014689
121Ankyloglossia (HP:0010296)1.63593913
122Short phalanx of the thumb (HP:0009660)1.63208539
123Alacrima (HP:0000522)1.63122006
124Hallux valgus (HP:0001822)1.62089343
125Choanal stenosis (HP:0000452)1.61803560
126Neonatal hypoglycemia (HP:0001998)1.61264984
127Patellar dislocation (HP:0002999)1.60943993
128Short middle phalanx of finger (HP:0005819)1.60838063
129Attention deficit hyperactivity disorder (HP:0007018)1.60467600
130Abnormality of the phalanges of the hallux (HP:0010057)1.60446575
131Omphalocele (HP:0001539)1.60017763
132Lip pit (HP:0100267)1.59970613
133Abnormality of chromosome segregation (HP:0002916)1.59834447
134Genu recurvatum (HP:0002816)1.59479345
135Broad metatarsal (HP:0001783)1.59319156
136Laryngomalacia (HP:0001601)1.58876682
137Nephroblastoma (Wilms tumor) (HP:0002667)1.58693564
138Partial duplication of thumb phalanx (HP:0009944)1.58568310
139Tracheomalacia (HP:0002779)1.58009116
140Sparse lateral eyebrow (HP:0005338)1.57864142
141Ulnar bowing (HP:0003031)1.57755530
142Bladder carcinoma (HP:0002862)1.57735807
143Bladder neoplasm (HP:0009725)1.57735807
144Papillary thyroid carcinoma (HP:0002895)1.57585643
145Insomnia (HP:0100785)1.56674242
146Abnormality of the intervertebral disk (HP:0005108)1.56664180
147Shawl scrotum (HP:0000049)1.56478352
148Abnormality of the incisor (HP:0000676)1.55638631
149Genetic anticipation (HP:0003743)1.55581899
150Hypopigmentation of the fundus (HP:0007894)1.55376206
151Preauricular skin tag (HP:0000384)1.54285139
152Diastasis recti (HP:0001540)1.52204910

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDK125.32149869
2LATS13.06974484
3BRD42.99034493
4CAMK1D2.98985679
5CAMK1G2.90488137
6CDC72.51694364
7MAP3K102.47746170
8EEF2K2.16647970
9SRPK12.13959819
10PKN22.07644618
11PDGFRA2.06670889
12SIK11.95827857
13TSSK61.94495465
14TRIB31.85671467
15RIPK11.84028629
16NTRK11.83139189
17MTOR1.78382409
18CDK61.72580594
19TNIK1.68648118
20FGFR21.65811022
21ICK1.65465756
22CASK1.63257872
23NEK21.61854110
24DDR21.61116123
25PTK61.56109474
26MAP3K91.51209049
27STK31.46831661
28DMPK1.41639292
29FGFR11.40703085
30SMG11.35207578
31FGFR31.31553685
32PRKD31.31252726
33TTN1.25041526
34ALK1.23257298
35SIK21.21974453
36ATR1.19763242
37PDGFRB1.17380932
38CDK41.09509585
39SCYL21.04936052
40CDC42BPA1.02845853
41BMX1.01967435
42CHEK11.00796712
43TYRO30.98200163
44ATM0.96671408
45PASK0.94385449
46SGK2230.93792644
47SGK4940.93792644
48CDK90.93401647
49SGK30.92945482
50WNK10.90738906
51TTK0.88678684
52PNCK0.88599644
53MKNK10.88301117
54ERBB20.87702974
55PTK20.86094742
56KSR10.83221071
57PAK20.80253039
58EPHA30.79783348
59MARK10.78549518
60NTRK20.78150377
61MKNK20.77876931
62CHEK20.77837507
63KSR20.77833726
64MELK0.77720759
65CDK20.77144691
66LATS20.76816900
67CHUK0.74619382
68FRK0.74606876
69CDK70.73578239
70CSNK1A1L0.72560632
71ERBB30.71999140
72CDK80.71610521
73RPS6KB20.71409681
74TAF10.70420263
75RET0.69539536
76EPHB20.68293721
77CDK10.64311019
78MAPK140.64184041
79PRKDC0.63955577
80RPS6KA40.62673462
81NUAK10.62126616
82STK100.61868751
83STK40.61565874
84CDK30.61272189
85SGK20.60100641
86CSNK1D0.59411072
87NTRK30.58582195
88PAK40.58497609
89PRKAA10.56688577
90MAPK100.55855535
91PLK30.55687537
92MAP3K70.55682061
93AKT30.55519896
94MAPK10.54540656
95PLK40.53763841
96INSRR0.53708235
97GSK3B0.53442494
98CAMK10.52762888
99ERN10.51634134
100AKT10.51076790
101NLK0.50120519
102WEE10.49060566
103PRKCH0.49013104
104CLK10.48866044
105SIK30.48267105
106AURKB0.48198369
107MARK20.47828490
108TGFBR10.47463353
109CSNK1E0.47313785
110MAPK80.47236875
111JAK10.46762420
112CAMK40.46133155
113ERBB40.45888928
114HIPK20.45388225
115SGK10.44772940
116BRSK20.43829636
117FER0.43461275
118YES10.43374360
119PRKD20.42123749
120MET0.40679432
121PLK10.39942606
122PRKAA20.39613598
123EIF2AK10.39379846
124MARK30.38973910
125AKT20.38850433
126FLT30.38683882
127FGFR40.38636685
128RPS6KB10.38519926
129STK240.37300957
130RAF10.36565819

Predicted pathways (KEGG)

RankGene SetZ-score
1Adherens junction_Homo sapiens_hsa045202.01166113
2Lysine degradation_Homo sapiens_hsa003101.90643654
3Basal cell carcinoma_Homo sapiens_hsa052171.89092532
4MicroRNAs in cancer_Homo sapiens_hsa052061.78288720
5mTOR signaling pathway_Homo sapiens_hsa041501.66293103
6Chronic myeloid leukemia_Homo sapiens_hsa052201.64460997
7Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.61948382
8mRNA surveillance pathway_Homo sapiens_hsa030151.56038430
9Hippo signaling pathway_Homo sapiens_hsa043901.55900458
10Proteoglycans in cancer_Homo sapiens_hsa052051.52219179
11Notch signaling pathway_Homo sapiens_hsa043301.51932919
12Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.49044179
13Thyroid hormone signaling pathway_Homo sapiens_hsa049191.47228374
14Hedgehog signaling pathway_Homo sapiens_hsa043401.43912461
15Cell cycle_Homo sapiens_hsa041101.43353798
16Small cell lung cancer_Homo sapiens_hsa052221.41897063
17Colorectal cancer_Homo sapiens_hsa052101.41788711
18Endometrial cancer_Homo sapiens_hsa052131.38424389
19TGF-beta signaling pathway_Homo sapiens_hsa043501.37096703
20Focal adhesion_Homo sapiens_hsa045101.33701275
21Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.30479005
22Dorso-ventral axis formation_Homo sapiens_hsa043201.30395465
23Prostate cancer_Homo sapiens_hsa052151.27944439
24Type II diabetes mellitus_Homo sapiens_hsa049301.27586782
25Wnt signaling pathway_Homo sapiens_hsa043101.26080616
26ECM-receptor interaction_Homo sapiens_hsa045121.26053048
27Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.25974007
28Glioma_Homo sapiens_hsa052141.19802402
29Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.16075804
30Neurotrophin signaling pathway_Homo sapiens_hsa047221.16074282
31HTLV-I infection_Homo sapiens_hsa051661.16062136
32Transcriptional misregulation in cancer_Homo sapiens_hsa052021.15999732
33Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.15184526
34Pancreatic cancer_Homo sapiens_hsa052121.13521858
35Non-small cell lung cancer_Homo sapiens_hsa052231.13324719
36Viral myocarditis_Homo sapiens_hsa054161.12783774
37RNA transport_Homo sapiens_hsa030131.09589972
38Viral carcinogenesis_Homo sapiens_hsa052031.03942144
39Central carbon metabolism in cancer_Homo sapiens_hsa052301.03636971
40Renal cell carcinoma_Homo sapiens_hsa052111.02539648
41Pathways in cancer_Homo sapiens_hsa052001.01804698
42Gap junction_Homo sapiens_hsa045401.01443747
43Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.96975117
44AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.96513834
45Estrogen signaling pathway_Homo sapiens_hsa049150.95731428
46Thyroid hormone synthesis_Homo sapiens_hsa049180.95358396
47Longevity regulating pathway - mammal_Homo sapiens_hsa042110.93776002
48Insulin resistance_Homo sapiens_hsa049310.93619132
49Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.93361929
50Melanogenesis_Homo sapiens_hsa049160.92373865
51Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.89441794
52Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.89248804
53Fatty acid biosynthesis_Homo sapiens_hsa000610.89083930
54GnRH signaling pathway_Homo sapiens_hsa049120.88822165
55Acute myeloid leukemia_Homo sapiens_hsa052210.87784240
56Thyroid cancer_Homo sapiens_hsa052160.86881696
57FoxO signaling pathway_Homo sapiens_hsa040680.86643787
58Oocyte meiosis_Homo sapiens_hsa041140.86232516
59Bladder cancer_Homo sapiens_hsa052190.86013469
60Hepatitis B_Homo sapiens_hsa051610.85305449
61ErbB signaling pathway_Homo sapiens_hsa040120.84952000
62Regulation of actin cytoskeleton_Homo sapiens_hsa048100.83128103
63Long-term depression_Homo sapiens_hsa047300.81044288
64Tight junction_Homo sapiens_hsa045300.81009177
65B cell receptor signaling pathway_Homo sapiens_hsa046620.80628071
66Toxoplasmosis_Homo sapiens_hsa051450.80359606
67Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.79923985
68Dilated cardiomyopathy_Homo sapiens_hsa054140.79556482
69Rap1 signaling pathway_Homo sapiens_hsa040150.79493796
70Axon guidance_Homo sapiens_hsa043600.78606063
71Leukocyte transendothelial migration_Homo sapiens_hsa046700.78584013
72Melanoma_Homo sapiens_hsa052180.78395214
73Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.78006135
74Phosphatidylinositol signaling system_Homo sapiens_hsa040700.77891021
75Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.77842421
76DNA replication_Homo sapiens_hsa030300.76237362
77Protein digestion and absorption_Homo sapiens_hsa049740.75863135
78Spliceosome_Homo sapiens_hsa030400.75737785
79PI3K-Akt signaling pathway_Homo sapiens_hsa041510.74499639
80Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.74146170
81Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.74013975
82AMPK signaling pathway_Homo sapiens_hsa041520.73831489
83Insulin signaling pathway_Homo sapiens_hsa049100.73110082
84p53 signaling pathway_Homo sapiens_hsa041150.72816205
85Glucagon signaling pathway_Homo sapiens_hsa049220.72636791
86VEGF signaling pathway_Homo sapiens_hsa043700.72598004
87Amoebiasis_Homo sapiens_hsa051460.72584910
88Herpes simplex infection_Homo sapiens_hsa051680.72027754
89HIF-1 signaling pathway_Homo sapiens_hsa040660.71640476
90Platelet activation_Homo sapiens_hsa046110.71584485
91cGMP-PKG signaling pathway_Homo sapiens_hsa040220.70770501
92T cell receptor signaling pathway_Homo sapiens_hsa046600.70589792
93MAPK signaling pathway_Homo sapiens_hsa040100.69398959
94Prolactin signaling pathway_Homo sapiens_hsa049170.68139815
95Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.68002768
96Long-term potentiation_Homo sapiens_hsa047200.66976145
97Cholinergic synapse_Homo sapiens_hsa047250.66809206
98Aldosterone synthesis and secretion_Homo sapiens_hsa049250.64491952
99One carbon pool by folate_Homo sapiens_hsa006700.64194976
100Choline metabolism in cancer_Homo sapiens_hsa052310.64178731
101Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.64132897
102Non-homologous end-joining_Homo sapiens_hsa034500.64127855
103Osteoclast differentiation_Homo sapiens_hsa043800.64005936
104Fanconi anemia pathway_Homo sapiens_hsa034600.63437665
105Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.61972775
106Carbohydrate digestion and absorption_Homo sapiens_hsa049730.61278426
107Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.60934537
108Glutamatergic synapse_Homo sapiens_hsa047240.60157725
109Ras signaling pathway_Homo sapiens_hsa040140.58698770
110Antigen processing and presentation_Homo sapiens_hsa046120.58571741
111Mismatch repair_Homo sapiens_hsa034300.58280935
112Inositol phosphate metabolism_Homo sapiens_hsa005620.58226232
113Phospholipase D signaling pathway_Homo sapiens_hsa040720.58204734
114TNF signaling pathway_Homo sapiens_hsa046680.57592542
115Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.57367671
116Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.54071214
117Prion diseases_Homo sapiens_hsa050200.50179944
118cAMP signaling pathway_Homo sapiens_hsa040240.49664498
119Hepatitis C_Homo sapiens_hsa051600.46933577
120Nucleotide excision repair_Homo sapiens_hsa034200.44784070

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