

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ribosomal small subunit assembly (GO:0000028) | 5.45308183 |
| 2 | CENP-A containing nucleosome assembly (GO:0034080) | 5.15585427 |
| 3 | chromatin remodeling at centromere (GO:0031055) | 5.08674500 |
| 4 | proteasome assembly (GO:0043248) | 4.84052917 |
| 5 | histone exchange (GO:0043486) | 4.51359649 |
| 6 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.48159185 |
| 7 | protein neddylation (GO:0045116) | 4.27272625 |
| 8 | rRNA modification (GO:0000154) | 4.21176245 |
| 9 | ribosomal large subunit biogenesis (GO:0042273) | 4.02282485 |
| 10 | protein complex biogenesis (GO:0070271) | 4.00532595 |
| 11 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.91197793 |
| 12 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.84902596 |
| 13 | DNA replication-independent nucleosome organization (GO:0034724) | 3.84902596 |
| 14 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.84018766 |
| 15 | ATP synthesis coupled proton transport (GO:0015986) | 3.80032400 |
| 16 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.80032400 |
| 17 | ribosomal small subunit biogenesis (GO:0042274) | 3.73535716 |
| 18 | purine nucleobase biosynthetic process (GO:0009113) | 3.68195174 |
| 19 | viral transcription (GO:0019083) | 3.67378427 |
| 20 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 3.66789736 |
| 21 | translational termination (GO:0006415) | 3.63488123 |
| 22 | pseudouridine synthesis (GO:0001522) | 3.62425565 |
| 23 | DNA replication checkpoint (GO:0000076) | 3.61998744 |
| 24 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.59985465 |
| 25 | base-excision repair, AP site formation (GO:0006285) | 3.56998759 |
| 26 | cullin deneddylation (GO:0010388) | 3.55488551 |
| 27 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.54659390 |
| 28 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.53918141 |
| 29 | NADH dehydrogenase complex assembly (GO:0010257) | 3.53918141 |
| 30 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.53918141 |
| 31 | formation of translation preinitiation complex (GO:0001731) | 3.52541671 |
| 32 | translational initiation (GO:0006413) | 3.51943855 |
| 33 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.51194163 |
| 34 | respiratory chain complex IV assembly (GO:0008535) | 3.50659159 |
| 35 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.49395952 |
| 36 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.49395952 |
| 37 | negative regulation of ligase activity (GO:0051352) | 3.48981213 |
| 38 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.48981213 |
| 39 | cotranslational protein targeting to membrane (GO:0006613) | 3.47852151 |
| 40 | rRNA methylation (GO:0031167) | 3.45942888 |
| 41 | chaperone-mediated protein transport (GO:0072321) | 3.42720983 |
| 42 | protein targeting to ER (GO:0045047) | 3.41854162 |
| 43 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.39936910 |
| 44 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.39540983 |
| 45 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.39213001 |
| 46 | DNA double-strand break processing (GO:0000729) | 3.38764657 |
| 47 | mitotic metaphase plate congression (GO:0007080) | 3.33920235 |
| 48 | synapsis (GO:0007129) | 3.31853382 |
| 49 | regulation of meiosis I (GO:0060631) | 3.31086447 |
| 50 | ribosome assembly (GO:0042255) | 3.30884005 |
| 51 | translation (GO:0006412) | 3.30263839 |
| 52 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.28838175 |
| 53 | nucleobase biosynthetic process (GO:0046112) | 3.28176310 |
| 54 | protein localization to endoplasmic reticulum (GO:0070972) | 3.27765841 |
| 55 | cellular component biogenesis (GO:0044085) | 3.27709743 |
| 56 | protein deneddylation (GO:0000338) | 3.27631806 |
| 57 | deoxyribonucleotide catabolic process (GO:0009264) | 3.25536963 |
| 58 | establishment of integrated proviral latency (GO:0075713) | 3.25469054 |
| 59 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.23710291 |
| 60 | DNA ligation (GO:0006266) | 3.23701804 |
| 61 | deoxyribose phosphate catabolic process (GO:0046386) | 3.22059389 |
| 62 | cytochrome complex assembly (GO:0017004) | 3.21700210 |
| 63 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.21475995 |
| 64 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.19887505 |
| 65 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.19747977 |
| 66 | IMP biosynthetic process (GO:0006188) | 3.19028084 |
| 67 | translational elongation (GO:0006414) | 3.18519267 |
| 68 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.18400287 |
| 69 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.17330486 |
| 70 | rRNA processing (GO:0006364) | 3.16213740 |
| 71 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.16106788 |
| 72 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.16106788 |
| 73 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.16106788 |
| 74 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.15485866 |
| 75 | regulation of mitochondrial translation (GO:0070129) | 3.15430595 |
| 76 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.12973208 |
| 77 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.12973208 |
| 78 | histone mRNA metabolic process (GO:0008334) | 3.10940442 |
| 79 | transcription from mitochondrial promoter (GO:0006390) | 3.10815101 |
| 80 | regulation of centriole replication (GO:0046599) | 3.10520754 |
| 81 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.08692047 |
| 82 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.08002694 |
| 83 | maturation of SSU-rRNA (GO:0030490) | 3.07289079 |
| 84 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.06125540 |
| 85 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.06125540 |
| 86 | DNA strand elongation (GO:0022616) | 3.04374374 |
| 87 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.03404293 |
| 88 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.03404293 |
| 89 | positive regulation of ligase activity (GO:0051351) | 3.03073379 |
| 90 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 3.02991853 |
| 91 | mitochondrial RNA metabolic process (GO:0000959) | 3.02955050 |
| 92 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.02869595 |
| 93 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.02869595 |
| 94 | rRNA metabolic process (GO:0016072) | 3.02797175 |
| 95 | metaphase plate congression (GO:0051310) | 3.01692429 |
| 96 | maturation of 5.8S rRNA (GO:0000460) | 3.01626632 |
| 97 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.00751124 |
| 98 | purine deoxyribonucleotide catabolic process (GO:0009155) | 2.99683397 |
| 99 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.99511474 |
| 100 | telomere maintenance via recombination (GO:0000722) | 2.95707776 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 5.08597018 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.54653878 |
| 3 | E2F7_22180533_ChIP-Seq_HELA_Human | 4.19123332 |
| 4 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.06410640 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.85891094 |
| 6 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.40833514 |
| 7 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.33120409 |
| 8 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.30822471 |
| 9 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.09833951 |
| 10 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.01108499 |
| 11 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 3.00520394 |
| 12 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.88884959 |
| 13 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.84208093 |
| 14 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.82327980 |
| 15 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.76008866 |
| 16 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.72395797 |
| 17 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.64963432 |
| 18 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.64904082 |
| 19 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.63400384 |
| 20 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.55904202 |
| 21 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.52695153 |
| 22 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.46583308 |
| 23 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.25673435 |
| 24 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 2.18888479 |
| 25 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.16623744 |
| 26 | TTF2_22483619_ChIP-Seq_HELA_Human | 2.14665948 |
| 27 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.06721476 |
| 28 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.06338664 |
| 29 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.02020424 |
| 30 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 2.01432062 |
| 31 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.01356951 |
| 32 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.96714835 |
| 33 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.96426376 |
| 34 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.93770500 |
| 35 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.92517794 |
| 36 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.91839061 |
| 37 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.90549328 |
| 38 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.84028989 |
| 39 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.74117794 |
| 40 | FUS_26573619_Chip-Seq_HEK293_Human | 1.73319835 |
| 41 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.72953358 |
| 42 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.71760348 |
| 43 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.70928271 |
| 44 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.70037467 |
| 45 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.65702026 |
| 46 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.65485292 |
| 47 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.52976750 |
| 48 | EWS_26573619_Chip-Seq_HEK293_Human | 1.47899723 |
| 49 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.47645929 |
| 50 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.46099145 |
| 51 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.44655322 |
| 52 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.43762113 |
| 53 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.39649757 |
| 54 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.39646017 |
| 55 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.37645644 |
| 56 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.33360957 |
| 57 | VDR_22108803_ChIP-Seq_LS180_Human | 1.33241891 |
| 58 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.30731053 |
| 59 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.26336152 |
| 60 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.25412969 |
| 61 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.20039886 |
| 62 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.19410731 |
| 63 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.18589504 |
| 64 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.14055741 |
| 65 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.09776580 |
| 66 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.09707061 |
| 67 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.07365127 |
| 68 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.07201767 |
| 69 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.06284052 |
| 70 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.03131648 |
| 71 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.00483237 |
| 72 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.00106296 |
| 73 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.99581562 |
| 74 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.98088365 |
| 75 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.96911695 |
| 76 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.96083155 |
| 77 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 0.94549840 |
| 78 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.93017970 |
| 79 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.92521527 |
| 80 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.92225218 |
| 81 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.87983865 |
| 82 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.85723049 |
| 83 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.84471309 |
| 84 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 0.83108838 |
| 85 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.82708797 |
| 86 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.82127756 |
| 87 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.80461921 |
| 88 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.80125394 |
| 89 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.77940657 |
| 90 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.77304859 |
| 91 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 0.77104603 |
| 92 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.75264698 |
| 93 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 0.75194009 |
| 94 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.74476836 |
| 95 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.73598991 |
| 96 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.72756600 |
| 97 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.72414506 |
| 98 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.71418623 |
| 99 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.70777478 |
| 100 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.68978861 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008058_abnormal_DNA_repair | 4.66784904 |
| 2 | MP0010094_abnormal_chromosome_stability | 3.79354811 |
| 3 | MP0004957_abnormal_blastocyst_morpholog | 3.61070603 |
| 4 | MP0002132_abnormal_respiratory_system | 3.21993269 |
| 5 | MP0009697_abnormal_copulation | 3.20122716 |
| 6 | MP0003806_abnormal_nucleotide_metabolis | 3.16670321 |
| 7 | MP0003077_abnormal_cell_cycle | 3.12061813 |
| 8 | MP0003693_abnormal_embryo_hatching | 3.07479616 |
| 9 | MP0003111_abnormal_nucleus_morphology | 3.03107791 |
| 10 | MP0003786_premature_aging | 2.89087653 |
| 11 | MP0003186_abnormal_redox_activity | 2.82553120 |
| 12 | MP0006292_abnormal_olfactory_placode | 2.67851958 |
| 13 | MP0008932_abnormal_embryonic_tissue | 2.55135347 |
| 14 | MP0005410_abnormal_fertilization | 2.51541323 |
| 15 | MP0008877_abnormal_DNA_methylation | 2.36620485 |
| 16 | MP0003718_maternal_effect | 2.35990077 |
| 17 | MP0006036_abnormal_mitochondrial_physio | 2.24253531 |
| 18 | MP0005084_abnormal_gallbladder_morpholo | 2.22125526 |
| 19 | MP0005075_abnormal_melanosome_morpholog | 2.09445109 |
| 20 | MP0001853_heart_inflammation | 2.06399518 |
| 21 | MP0002138_abnormal_hepatobiliary_system | 2.05434239 |
| 22 | MP0008007_abnormal_cellular_replicative | 2.02855546 |
| 23 | MP0008995_early_reproductive_senescence | 2.02029637 |
| 24 | MP0006054_spinal_hemorrhage | 1.82402141 |
| 25 | MP0002938_white_spotting | 1.81797226 |
| 26 | MP0008004_abnormal_stomach_pH | 1.79964422 |
| 27 | MP0003941_abnormal_skin_development | 1.76190514 |
| 28 | MP0001929_abnormal_gametogenesis | 1.67039847 |
| 29 | MP0006035_abnormal_mitochondrial_morpho | 1.63569396 |
| 30 | MP0002210_abnormal_sex_determination | 1.53641175 |
| 31 | MP0008057_abnormal_DNA_replication | 1.47997888 |
| 32 | MP0001529_abnormal_vocalization | 1.45287771 |
| 33 | MP0002160_abnormal_reproductive_system | 1.39113344 |
| 34 | MP0001293_anophthalmia | 1.37870975 |
| 35 | MP0009379_abnormal_foot_pigmentation | 1.37838223 |
| 36 | MP0002837_dystrophic_cardiac_calcinosis | 1.37779397 |
| 37 | MP0008789_abnormal_olfactory_epithelium | 1.37158180 |
| 38 | MP0003890_abnormal_embryonic-extraembry | 1.36314704 |
| 39 | MP0001145_abnormal_male_reproductive | 1.34699308 |
| 40 | MP0003252_abnormal_bile_duct | 1.34503221 |
| 41 | MP0000372_irregular_coat_pigmentation | 1.30511001 |
| 42 | MP0003646_muscle_fatigue | 1.26780602 |
| 43 | MP0001727_abnormal_embryo_implantation | 1.26027310 |
| 44 | MP0003283_abnormal_digestive_organ | 1.24366113 |
| 45 | MP0003195_calcinosis | 1.21774737 |
| 46 | MP0000653_abnormal_sex_gland | 1.21606445 |
| 47 | MP0003698_abnormal_male_reproductive | 1.20639731 |
| 48 | MP0001697_abnormal_embryo_size | 1.19954155 |
| 49 | MP0003136_yellow_coat_color | 1.19396862 |
| 50 | MP0006072_abnormal_retinal_apoptosis | 1.19319433 |
| 51 | MP0001764_abnormal_homeostasis | 1.19197578 |
| 52 | MP0003567_abnormal_fetal_cardiomyocyte | 1.13760657 |
| 53 | MP0000350_abnormal_cell_proliferation | 1.11040942 |
| 54 | MP0005380_embryogenesis_phenotype | 1.10811316 |
| 55 | MP0001672_abnormal_embryogenesis/_devel | 1.10811316 |
| 56 | MP0000313_abnormal_cell_death | 1.06865306 |
| 57 | MP0000358_abnormal_cell_content/ | 1.06532276 |
| 58 | MP0004147_increased_porphyrin_level | 1.05349069 |
| 59 | MP0001730_embryonic_growth_arrest | 1.01786118 |
| 60 | MP0001485_abnormal_pinna_reflex | 0.96986633 |
| 61 | MP0002080_prenatal_lethality | 0.94565569 |
| 62 | MP0002084_abnormal_developmental_patter | 0.93006595 |
| 63 | MP0005394_taste/olfaction_phenotype | 0.89715645 |
| 64 | MP0005499_abnormal_olfactory_system | 0.89715645 |
| 65 | MP0003984_embryonic_growth_retardation | 0.89514405 |
| 66 | MP0002638_abnormal_pupillary_reflex | 0.89302215 |
| 67 | MP0002088_abnormal_embryonic_growth/wei | 0.87963475 |
| 68 | MP0005220_abnormal_exocrine_pancreas | 0.83855727 |
| 69 | MP0002085_abnormal_embryonic_tissue | 0.82432036 |
| 70 | MP0005670_abnormal_white_adipose | 0.81718201 |
| 71 | MP0005408_hypopigmentation | 0.79983575 |
| 72 | MP0005332_abnormal_amino_acid | 0.79649603 |
| 73 | MP0001661_extended_life_span | 0.78845443 |
| 74 | MP0000749_muscle_degeneration | 0.76879326 |
| 75 | MP0005395_other_phenotype | 0.76318303 |
| 76 | MP0002736_abnormal_nociception_after | 0.75485071 |
| 77 | MP0004215_abnormal_myocardial_fiber | 0.75456068 |
| 78 | MP0005330_cardiomyopathy | 0.74707071 |
| 79 | MP0005389_reproductive_system_phenotype | 0.73795552 |
| 80 | MP0005085_abnormal_gallbladder_physiolo | 0.73639582 |
| 81 | MP0000049_abnormal_middle_ear | 0.72483405 |
| 82 | MP0001119_abnormal_female_reproductive | 0.71233616 |
| 83 | MP0002019_abnormal_tumor_incidence | 0.71034112 |
| 84 | MP0002277_abnormal_respiratory_mucosa | 0.69273895 |
| 85 | MP0002254_reproductive_system_inflammat | 0.68449824 |
| 86 | MP0010030_abnormal_orbit_morphology | 0.67824784 |
| 87 | MP0000013_abnormal_adipose_tissue | 0.67196498 |
| 88 | MP0003937_abnormal_limbs/digits/tail_de | 0.67025844 |
| 89 | MP0002102_abnormal_ear_morphology | 0.66484525 |
| 90 | MP0004133_heterotaxia | 0.65800481 |
| 91 | MP0002161_abnormal_fertility/fecundity | 0.64915714 |
| 92 | MP0001666_abnormal_nutrient_absorption | 0.63433447 |
| 93 | MP0004084_abnormal_cardiac_muscle | 0.63243145 |
| 94 | MP0000613_abnormal_salivary_gland | 0.60937790 |
| 95 | MP0010386_abnormal_urinary_bladder | 0.60442820 |
| 96 | MP0008875_abnormal_xenobiotic_pharmacok | 0.60359795 |
| 97 | MP0000516_abnormal_urinary_system | 0.59519876 |
| 98 | MP0005367_renal/urinary_system_phenotyp | 0.59519876 |
| 99 | MP0002269_muscular_atrophy | 0.59110371 |
| 100 | MP0005379_endocrine/exocrine_gland_phen | 0.58411984 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Increased hepatocellular lipid droplets (HP:0006565) | 4.77328893 |
| 2 | Lipid accumulation in hepatocytes (HP:0006561) | 4.60764279 |
| 3 | Acute necrotizing encephalopathy (HP:0006965) | 4.56290081 |
| 4 | Acute encephalopathy (HP:0006846) | 4.30914385 |
| 5 | Renal Fanconi syndrome (HP:0001994) | 4.30381322 |
| 6 | Increased CSF lactate (HP:0002490) | 4.25841075 |
| 7 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.22330679 |
| 8 | Mitochondrial inheritance (HP:0001427) | 4.09153640 |
| 9 | Progressive macrocephaly (HP:0004481) | 3.69466102 |
| 10 | Type I transferrin isoform profile (HP:0003642) | 3.45388774 |
| 11 | Exertional dyspnea (HP:0002875) | 3.37544156 |
| 12 | Hepatocellular necrosis (HP:0001404) | 3.36886261 |
| 13 | Increased serum lactate (HP:0002151) | 3.20313678 |
| 14 | Cerebral edema (HP:0002181) | 3.16231619 |
| 15 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 3.14091668 |
| 16 | Abnormality of alanine metabolism (HP:0010916) | 3.14091668 |
| 17 | Hyperalaninemia (HP:0003348) | 3.14091668 |
| 18 | Increased intramyocellular lipid droplets (HP:0012240) | 3.12028922 |
| 19 | Reticulocytopenia (HP:0001896) | 3.12025468 |
| 20 | Reduced antithrombin III activity (HP:0001976) | 3.03983763 |
| 21 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.00063418 |
| 22 | Hepatic necrosis (HP:0002605) | 2.97021697 |
| 23 | Lactic acidosis (HP:0003128) | 2.82836936 |
| 24 | Macrocytic anemia (HP:0001972) | 2.81100048 |
| 25 | Aplastic anemia (HP:0001915) | 2.80737470 |
| 26 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.76112451 |
| 27 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.76112451 |
| 28 | Respiratory difficulties (HP:0002880) | 2.70713247 |
| 29 | Increased muscle lipid content (HP:0009058) | 2.70596692 |
| 30 | Congenital, generalized hypertrichosis (HP:0004540) | 2.70071010 |
| 31 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.67455411 |
| 32 | Abnormality of renal resorption (HP:0011038) | 2.65837584 |
| 33 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.65634560 |
| 34 | Abnormality of methionine metabolism (HP:0010901) | 2.64406508 |
| 35 | Oral leukoplakia (HP:0002745) | 2.61230936 |
| 36 | Abnormal number of erythroid precursors (HP:0012131) | 2.58451513 |
| 37 | Exercise intolerance (HP:0003546) | 2.53882101 |
| 38 | Pancytopenia (HP:0001876) | 2.52538050 |
| 39 | Stenosis of the external auditory canal (HP:0000402) | 2.52075582 |
| 40 | Degeneration of anterior horn cells (HP:0002398) | 2.50961729 |
| 41 | Abnormality of the anterior horn cell (HP:0006802) | 2.50961729 |
| 42 | Abnormal spermatogenesis (HP:0008669) | 2.50576676 |
| 43 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.47019112 |
| 44 | Respiratory failure (HP:0002878) | 2.46388220 |
| 45 | Abnormality of urine glucose concentration (HP:0011016) | 2.45281289 |
| 46 | Glycosuria (HP:0003076) | 2.45281289 |
| 47 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.43912537 |
| 48 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.43912537 |
| 49 | Abnormal protein glycosylation (HP:0012346) | 2.43912537 |
| 50 | Abnormal glycosylation (HP:0012345) | 2.43912537 |
| 51 | Abnormality of placental membranes (HP:0011409) | 2.38657884 |
| 52 | Amniotic constriction ring (HP:0009775) | 2.38657884 |
| 53 | Abnormality of serum amino acid levels (HP:0003112) | 2.34866494 |
| 54 | Rough bone trabeculation (HP:0100670) | 2.31982190 |
| 55 | 3-Methylglutaconic aciduria (HP:0003535) | 2.31525494 |
| 56 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.29571212 |
| 57 | Meckel diverticulum (HP:0002245) | 2.29290792 |
| 58 | Colon cancer (HP:0003003) | 2.24545145 |
| 59 | Increased serum pyruvate (HP:0003542) | 2.21757885 |
| 60 | Leukodystrophy (HP:0002415) | 2.20180456 |
| 61 | Lethargy (HP:0001254) | 2.17453890 |
| 62 | Microvesicular hepatic steatosis (HP:0001414) | 2.17237208 |
| 63 | Abnormality of the ileum (HP:0001549) | 2.16104409 |
| 64 | Chromsome breakage (HP:0040012) | 2.15232206 |
| 65 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.13847629 |
| 66 | Abnormality of chromosome stability (HP:0003220) | 2.12229317 |
| 67 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.11092598 |
| 68 | Methylmalonic acidemia (HP:0002912) | 2.10717262 |
| 69 | Hypoplasia of the pons (HP:0012110) | 2.03372610 |
| 70 | Hyperglycinemia (HP:0002154) | 2.02368035 |
| 71 | Abnormality of the preputium (HP:0100587) | 2.02268016 |
| 72 | Birth length less than 3rd percentile (HP:0003561) | 2.02075402 |
| 73 | Small intestinal stenosis (HP:0012848) | 2.01553756 |
| 74 | Duodenal stenosis (HP:0100867) | 2.01553756 |
| 75 | Azoospermia (HP:0000027) | 2.00746842 |
| 76 | Pallor (HP:0000980) | 1.99849748 |
| 77 | True hermaphroditism (HP:0010459) | 1.99713173 |
| 78 | Hyperphosphaturia (HP:0003109) | 1.98473007 |
| 79 | Optic disc pallor (HP:0000543) | 1.97609697 |
| 80 | Carpal bone hypoplasia (HP:0001498) | 1.96768152 |
| 81 | CNS demyelination (HP:0007305) | 1.96732614 |
| 82 | Progressive muscle weakness (HP:0003323) | 1.94543128 |
| 83 | Abnormality of the pons (HP:0007361) | 1.93990366 |
| 84 | Abnormal trabecular bone morphology (HP:0100671) | 1.93353471 |
| 85 | Type 2 muscle fiber atrophy (HP:0003554) | 1.91706178 |
| 86 | Generalized aminoaciduria (HP:0002909) | 1.90141653 |
| 87 | Pancreatic cysts (HP:0001737) | 1.89430886 |
| 88 | Abnormal lung lobation (HP:0002101) | 1.87063611 |
| 89 | Nephronophthisis (HP:0000090) | 1.85527138 |
| 90 | Absent thumb (HP:0009777) | 1.83791855 |
| 91 | Pancreatic fibrosis (HP:0100732) | 1.82063434 |
| 92 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.81658067 |
| 93 | Absent/shortened dynein arms (HP:0200106) | 1.81658067 |
| 94 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 1.79586471 |
| 95 | Myelodysplasia (HP:0002863) | 1.79204623 |
| 96 | Horseshoe kidney (HP:0000085) | 1.78407669 |
| 97 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.78267072 |
| 98 | Gonadotropin excess (HP:0000837) | 1.77187172 |
| 99 | Median cleft lip (HP:0000161) | 1.75545734 |
| 100 | Secondary amenorrhea (HP:0000869) | 1.73940311 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | STK16 | 5.59094414 |
| 2 | MST4 | 3.73248840 |
| 3 | ZAK | 3.60552668 |
| 4 | PBK | 3.38165961 |
| 5 | CDK19 | 3.34316750 |
| 6 | BUB1 | 3.22413252 |
| 7 | EIF2AK1 | 2.68746321 |
| 8 | PLK4 | 2.65599891 |
| 9 | VRK2 | 2.65022562 |
| 10 | EIF2AK3 | 2.48027651 |
| 11 | BRSK2 | 2.39924592 |
| 12 | WEE1 | 2.37323290 |
| 13 | VRK1 | 2.13156632 |
| 14 | CDC7 | 2.11127994 |
| 15 | TLK1 | 2.07539757 |
| 16 | TTK | 2.06362609 |
| 17 | NEK1 | 2.02820728 |
| 18 | SRPK1 | 1.95531022 |
| 19 | CCNB1 | 1.95237723 |
| 20 | MAP3K12 | 1.90080480 |
| 21 | NME2 | 1.83683708 |
| 22 | PLK3 | 1.75811735 |
| 23 | TRIM28 | 1.67696962 |
| 24 | TSSK6 | 1.52504074 |
| 25 | PLK1 | 1.45098632 |
| 26 | PDK2 | 1.43281998 |
| 27 | MKNK1 | 1.32995035 |
| 28 | PLK2 | 1.30166533 |
| 29 | NUAK1 | 1.28081647 |
| 30 | MKNK2 | 1.24926978 |
| 31 | BMPR1B | 1.20494465 |
| 32 | WNK3 | 1.19405332 |
| 33 | BCKDK | 1.13129976 |
| 34 | PASK | 1.11820210 |
| 35 | TAF1 | 1.05034191 |
| 36 | MUSK | 1.02024063 |
| 37 | PNCK | 1.00817454 |
| 38 | MAP4K2 | 0.98001816 |
| 39 | BRSK1 | 0.91377031 |
| 40 | NME1 | 0.90413683 |
| 41 | LMTK2 | 0.89340759 |
| 42 | AURKB | 0.88603159 |
| 43 | RPS6KB2 | 0.85295376 |
| 44 | SCYL2 | 0.84186763 |
| 45 | CHEK2 | 0.81374102 |
| 46 | STK38L | 0.79168891 |
| 47 | INSRR | 0.79103404 |
| 48 | ATR | 0.78259441 |
| 49 | PAK4 | 0.77849490 |
| 50 | MYLK | 0.72107173 |
| 51 | BMPR2 | 0.66248663 |
| 52 | RPS6KA5 | 0.65118781 |
| 53 | ACVR1B | 0.63303522 |
| 54 | TGFBR1 | 0.62857509 |
| 55 | GRK1 | 0.61743201 |
| 56 | TEC | 0.60050030 |
| 57 | STK4 | 0.59413707 |
| 58 | CSNK2A1 | 0.58502288 |
| 59 | DAPK3 | 0.57389272 |
| 60 | BRD4 | 0.56403748 |
| 61 | ABL2 | 0.54744808 |
| 62 | CDK7 | 0.54534147 |
| 63 | TNIK | 0.53938247 |
| 64 | ILK | 0.52444607 |
| 65 | CSNK2A2 | 0.51016834 |
| 66 | AURKA | 0.50467872 |
| 67 | MATK | 0.47882527 |
| 68 | EIF2AK2 | 0.47452582 |
| 69 | NEK2 | 0.45555593 |
| 70 | ATM | 0.45332429 |
| 71 | FLT3 | 0.43754234 |
| 72 | OXSR1 | 0.43555760 |
| 73 | STK3 | 0.43372431 |
| 74 | DAPK1 | 0.43255500 |
| 75 | DYRK3 | 0.42200391 |
| 76 | CHEK1 | 0.41146316 |
| 77 | MARK3 | 0.37849717 |
| 78 | ADRBK2 | 0.37186907 |
| 79 | PINK1 | 0.36160870 |
| 80 | ERBB3 | 0.36012008 |
| 81 | CSNK1G1 | 0.35654947 |
| 82 | MAP3K8 | 0.34655741 |
| 83 | CDK8 | 0.34277007 |
| 84 | OBSCN | 0.33386809 |
| 85 | AKT2 | 0.33118904 |
| 86 | DYRK2 | 0.29715251 |
| 87 | KIT | 0.28839253 |
| 88 | CSNK1G3 | 0.27170254 |
| 89 | TIE1 | 0.26205653 |
| 90 | PIM2 | 0.26120355 |
| 91 | MAP3K5 | 0.25978824 |
| 92 | STK10 | 0.24695563 |
| 93 | BRAF | 0.24430818 |
| 94 | PRKCE | 0.21940038 |
| 95 | PRKCI | 0.20976798 |
| 96 | STK39 | 0.20038698 |
| 97 | ERBB4 | 0.19388642 |
| 98 | CDK9 | 0.19068952 |
| 99 | CSNK1G2 | 0.18901757 |
| 100 | CLK1 | 0.17976523 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.23193421 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 3.88707323 |
| 3 | DNA replication_Homo sapiens_hsa03030 | 3.42910027 |
| 4 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.16529378 |
| 5 | Mismatch repair_Homo sapiens_hsa03430 | 3.15658236 |
| 6 | Base excision repair_Homo sapiens_hsa03410 | 2.99968190 |
| 7 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.74678101 |
| 8 | Protein export_Homo sapiens_hsa03060 | 2.52869722 |
| 9 | Parkinsons disease_Homo sapiens_hsa05012 | 2.50855622 |
| 10 | RNA polymerase_Homo sapiens_hsa03020 | 2.48401656 |
| 11 | Homologous recombination_Homo sapiens_hsa03440 | 2.48110938 |
| 12 | RNA transport_Homo sapiens_hsa03013 | 2.28132528 |
| 13 | Spliceosome_Homo sapiens_hsa03040 | 2.10037623 |
| 14 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.09879085 |
| 15 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.00628342 |
| 16 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.99536469 |
| 17 | Huntingtons disease_Homo sapiens_hsa05016 | 1.85448311 |
| 18 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.82315526 |
| 19 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.79654392 |
| 20 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.78234091 |
| 21 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.78020720 |
| 22 | Basal transcription factors_Homo sapiens_hsa03022 | 1.77565851 |
| 23 | RNA degradation_Homo sapiens_hsa03018 | 1.75488920 |
| 24 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.67289325 |
| 25 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.57622099 |
| 26 | Purine metabolism_Homo sapiens_hsa00230 | 1.37236897 |
| 27 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.35742773 |
| 28 | Alzheimers disease_Homo sapiens_hsa05010 | 1.34342621 |
| 29 | Cell cycle_Homo sapiens_hsa04110 | 1.34253680 |
| 30 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.33519891 |
| 31 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.32693761 |
| 32 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.24849793 |
| 33 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.19142256 |
| 34 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.14567898 |
| 35 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.13140154 |
| 36 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.11595132 |
| 37 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.10470581 |
| 38 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.07215906 |
| 39 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.04577106 |
| 40 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.02822994 |
| 41 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.02473130 |
| 42 | Peroxisome_Homo sapiens_hsa04146 | 1.01961436 |
| 43 | Sulfur relay system_Homo sapiens_hsa04122 | 1.01850307 |
| 44 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.99417449 |
| 45 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.97957087 |
| 46 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.94023189 |
| 47 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.89845879 |
| 48 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.83370532 |
| 49 | Asthma_Homo sapiens_hsa05310 | 0.81340846 |
| 50 | Carbon metabolism_Homo sapiens_hsa01200 | 0.81033867 |
| 51 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.77428585 |
| 52 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.77323280 |
| 53 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.76990676 |
| 54 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.76267737 |
| 55 | Metabolic pathways_Homo sapiens_hsa01100 | 0.75392705 |
| 56 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.74799364 |
| 57 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.73553196 |
| 58 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.72949740 |
| 59 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.72612573 |
| 60 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.72278098 |
| 61 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.71073726 |
| 62 | Retinol metabolism_Homo sapiens_hsa00830 | 0.68587831 |
| 63 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.67066876 |
| 64 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.66422311 |
| 65 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.65445361 |
| 66 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.64153078 |
| 67 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.63172186 |
| 68 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.61050062 |
| 69 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.60755069 |
| 70 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.60348340 |
| 71 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.59671984 |
| 72 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.57998927 |
| 73 | Legionellosis_Homo sapiens_hsa05134 | 0.55861283 |
| 74 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.55170635 |
| 75 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.54758777 |
| 76 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.50766583 |
| 77 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.49852420 |
| 78 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.48351189 |
| 79 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.42493223 |
| 80 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.38772381 |
| 81 | Alcoholism_Homo sapiens_hsa05034 | 0.36676002 |
| 82 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.36630334 |
| 83 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.36448506 |
| 84 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.36337368 |
| 85 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.32673096 |
| 86 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.32527429 |
| 87 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.32310453 |
| 88 | Phototransduction_Homo sapiens_hsa04744 | 0.29361457 |
| 89 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.28513855 |
| 90 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.28227703 |
| 91 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.25941772 |
| 92 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.25766272 |
| 93 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.24549834 |
| 94 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.21318990 |
| 95 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.20484471 |
| 96 | Allograft rejection_Homo sapiens_hsa05330 | 0.19505975 |
| 97 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.18978128 |
| 98 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.18715428 |
| 99 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.16890058 |
| 100 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.16695516 |

