

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of DNA endoreduplication (GO:0032875) | 5.56769740 |
| 2 | establishment of integrated proviral latency (GO:0075713) | 5.19395205 |
| 3 | CENP-A containing nucleosome assembly (GO:0034080) | 5.04553150 |
| 4 | chromatin remodeling at centromere (GO:0031055) | 5.03205707 |
| 5 | formation of translation preinitiation complex (GO:0001731) | 4.76892019 |
| 6 | proteasome assembly (GO:0043248) | 4.57967160 |
| 7 | transcription from mitochondrial promoter (GO:0006390) | 4.56231868 |
| 8 | ribosome assembly (GO:0042255) | 4.46932133 |
| 9 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.44721329 |
| 10 | histone exchange (GO:0043486) | 4.39618939 |
| 11 | mitochondrial RNA metabolic process (GO:0000959) | 4.38284161 |
| 12 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 4.32472947 |
| 13 | DNA replication-dependent nucleosome assembly (GO:0006335) | 4.29025593 |
| 14 | DNA replication-dependent nucleosome organization (GO:0034723) | 4.29025593 |
| 15 | DNA strand elongation (GO:0022616) | 4.17666099 |
| 16 | DNA replication-independent nucleosome assembly (GO:0006336) | 4.08521426 |
| 17 | DNA replication-independent nucleosome organization (GO:0034724) | 4.08521426 |
| 18 | establishment of viral latency (GO:0019043) | 3.88625118 |
| 19 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.87477769 |
| 20 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.83195321 |
| 21 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.83195321 |
| 22 | spliceosomal snRNP assembly (GO:0000387) | 3.79609475 |
| 23 | termination of RNA polymerase II transcription (GO:0006369) | 3.70836965 |
| 24 | DNA replication checkpoint (GO:0000076) | 3.67843824 |
| 25 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.67556227 |
| 26 | regulation of helicase activity (GO:0051095) | 3.66547641 |
| 27 | DNA ligation (GO:0006266) | 3.64858005 |
| 28 | DNA replication initiation (GO:0006270) | 3.64146394 |
| 29 | positive regulation of cellular response to oxidative stress (GO:1900409) | 3.60591444 |
| 30 | positive regulation of response to oxidative stress (GO:1902884) | 3.60591444 |
| 31 | mitotic metaphase plate congression (GO:0007080) | 3.58911728 |
| 32 | pseudouridine synthesis (GO:0001522) | 3.58751172 |
| 33 | protein localization to kinetochore (GO:0034501) | 3.58022610 |
| 34 | cullin deneddylation (GO:0010388) | 3.55595664 |
| 35 | histone mRNA metabolic process (GO:0008334) | 3.49039031 |
| 36 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.47899253 |
| 37 | protein deneddylation (GO:0000338) | 3.45718664 |
| 38 | regulation of centriole replication (GO:0046599) | 3.40715759 |
| 39 | maturation of 5.8S rRNA (GO:0000460) | 3.35150024 |
| 40 | metaphase plate congression (GO:0051310) | 3.32613621 |
| 41 | ribosome biogenesis (GO:0042254) | 3.30685125 |
| 42 | rRNA modification (GO:0000154) | 3.28981786 |
| 43 | telomere maintenance via recombination (GO:0000722) | 3.28315041 |
| 44 | L-serine metabolic process (GO:0006563) | 3.27777350 |
| 45 | mRNA splicing, via spliceosome (GO:0000398) | 3.27552026 |
| 46 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377) | 3.27552026 |
| 47 | ATP-dependent chromatin remodeling (GO:0043044) | 3.27003212 |
| 48 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.25050805 |
| 49 | RNA splicing, via transesterification reactions (GO:0000375) | 3.24537437 |
| 50 | DNA-templated transcription, termination (GO:0006353) | 3.23592662 |
| 51 | DNA double-strand break processing (GO:0000729) | 3.21992325 |
| 52 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 3.19909750 |
| 53 | kinetochore organization (GO:0051383) | 3.19708481 |
| 54 | cilium or flagellum-dependent cell motility (GO:0001539) | 3.19258621 |
| 55 | mitotic recombination (GO:0006312) | 3.16702444 |
| 56 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.10937281 |
| 57 | non-recombinational repair (GO:0000726) | 3.10937281 |
| 58 | chaperone-mediated protein transport (GO:0072321) | 3.07505239 |
| 59 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.06852759 |
| 60 | termination of RNA polymerase III transcription (GO:0006386) | 3.06852759 |
| 61 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.06506357 |
| 62 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class | 3.03792748 |
| 63 | tRNA methylation (GO:0030488) | 3.03609449 |
| 64 | regulation of transcription from RNA polymerase I promoter (GO:0006356) | 3.03205444 |
| 65 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 3.00929308 |
| 66 | tRNA aminoacylation for protein translation (GO:0006418) | 3.00034295 |
| 67 | DNA topological change (GO:0006265) | 2.99961246 |
| 68 | DNA unwinding involved in DNA replication (GO:0006268) | 2.97254018 |
| 69 | negative regulation of RNA splicing (GO:0033119) | 2.96549534 |
| 70 | regulation of oxidative stress-induced neuron death (GO:1903203) | 2.95720954 |
| 71 | rRNA processing (GO:0006364) | 2.95594535 |
| 72 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 2.94892533 |
| 73 | regulation of mitochondrial translation (GO:0070129) | 2.93929924 |
| 74 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 2.92092188 |
| 75 | negative regulation of mRNA processing (GO:0050686) | 2.91550252 |
| 76 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.91055865 |
| 77 | postreplication repair (GO:0006301) | 2.90428056 |
| 78 | tRNA aminoacylation (GO:0043039) | 2.89506249 |
| 79 | amino acid activation (GO:0043038) | 2.89506249 |
| 80 | telomere maintenance via telomere lengthening (GO:0010833) | 2.88832247 |
| 81 | chromatin assembly or disassembly (GO:0006333) | 2.88135550 |
| 82 | regulation of DNA-dependent DNA replication (GO:0090329) | 2.84891860 |
| 83 | somatic diversification of immunoglobulins (GO:0016445) | 2.83774539 |
| 84 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.83516307 |
| 85 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 2.82993367 |
| 86 | isotype switching (GO:0045190) | 2.82993367 |
| 87 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 2.82993367 |
| 88 | somatic recombination of immunoglobulin gene segments (GO:0016447) | 2.81932026 |
| 89 | DNA deamination (GO:0045006) | 2.81920071 |
| 90 | rRNA metabolic process (GO:0016072) | 2.81181142 |
| 91 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 2.80094861 |
| 92 | purine nucleobase biosynthetic process (GO:0009113) | 2.79287439 |
| 93 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.79134971 |
| 94 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.79134971 |
| 95 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.78049530 |
| 96 | DNA damage response, detection of DNA damage (GO:0042769) | 2.77869715 |
| 97 | kinetochore assembly (GO:0051382) | 2.77567811 |
| 98 | protein localization to chromosome, centromeric region (GO:0071459) | 2.77173045 |
| 99 | ribonucleoprotein complex assembly (GO:0022618) | 2.76020747 |
| 100 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 2.74201410 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 6.93120308 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.43979310 |
| 3 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 4.04691537 |
| 4 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.93850085 |
| 5 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.76254848 |
| 6 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.47523957 |
| 7 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.24694733 |
| 8 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 3.04049883 |
| 9 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.89429202 |
| 10 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.84569916 |
| 11 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.79389666 |
| 12 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.77609711 |
| 13 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.74051929 |
| 14 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.71457269 |
| 15 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.69760241 |
| 16 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.59558923 |
| 17 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.58764756 |
| 18 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.53233467 |
| 19 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.44781967 |
| 20 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.39721831 |
| 21 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.39511143 |
| 22 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.37662034 |
| 23 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.35960549 |
| 24 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.30648778 |
| 25 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 2.22761983 |
| 26 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.20038549 |
| 27 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 2.15706005 |
| 28 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.10699702 |
| 29 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 2.01252298 |
| 30 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.95460399 |
| 31 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.90698191 |
| 32 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.84372369 |
| 33 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.81709265 |
| 34 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.81198974 |
| 35 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.81156804 |
| 36 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.78792944 |
| 37 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.75243314 |
| 38 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.74826035 |
| 39 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.74465640 |
| 40 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.73801238 |
| 41 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.73652518 |
| 42 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.73110406 |
| 43 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.69764084 |
| 44 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.68326993 |
| 45 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.68263803 |
| 46 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.67723080 |
| 47 | EWS_26573619_Chip-Seq_HEK293_Human | 1.62064509 |
| 48 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.60439784 |
| 49 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.59019058 |
| 50 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.58848665 |
| 51 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.56405642 |
| 52 | VDR_22108803_ChIP-Seq_LS180_Human | 1.54159293 |
| 53 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.45054053 |
| 54 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.42604558 |
| 55 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.38326223 |
| 56 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.37645817 |
| 57 | FUS_26573619_Chip-Seq_HEK293_Human | 1.35732909 |
| 58 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.34180003 |
| 59 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.31258701 |
| 60 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.29437217 |
| 61 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.27611280 |
| 62 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.26130006 |
| 63 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.22140972 |
| 64 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.21930648 |
| 65 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.15806570 |
| 66 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.10989511 |
| 67 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.10478304 |
| 68 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.08425311 |
| 69 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.07580715 |
| 70 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.05882060 |
| 71 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.05844474 |
| 72 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.05008470 |
| 73 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.02785314 |
| 74 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.01696485 |
| 75 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.00119036 |
| 76 | KDM5A_27292631_Chip-Seq_BREAST_Human | 0.99547304 |
| 77 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.96016713 |
| 78 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 0.90829141 |
| 79 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.88616596 |
| 80 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 0.86920913 |
| 81 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.84151792 |
| 82 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.84092016 |
| 83 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.83663774 |
| 84 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 0.82693822 |
| 85 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.75553160 |
| 86 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.73338864 |
| 87 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.73195200 |
| 88 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.73032817 |
| 89 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 0.72291468 |
| 90 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.72090563 |
| 91 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.71754462 |
| 92 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.70793588 |
| 93 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 0.69343084 |
| 94 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.68012486 |
| 95 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 0.67868776 |
| 96 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.67864982 |
| 97 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.67784149 |
| 98 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 0.67507964 |
| 99 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.67444767 |
| 100 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 0.66338771 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0006292_abnormal_olfactory_placode | 5.08315286 |
| 2 | MP0010094_abnormal_chromosome_stability | 4.73734262 |
| 3 | MP0008007_abnormal_cellular_replicative | 3.98637537 |
| 4 | MP0003693_abnormal_embryo_hatching | 3.71928679 |
| 5 | MP0004957_abnormal_blastocyst_morpholog | 3.66008118 |
| 6 | MP0008058_abnormal_DNA_repair | 3.57627368 |
| 7 | MP0003111_abnormal_nucleus_morphology | 3.54693000 |
| 8 | MP0009697_abnormal_copulation | 3.03565232 |
| 9 | MP0008057_abnormal_DNA_replication | 2.87081919 |
| 10 | MP0003077_abnormal_cell_cycle | 2.86636104 |
| 11 | MP0003806_abnormal_nucleotide_metabolis | 2.33649780 |
| 12 | MP0003136_yellow_coat_color | 2.26062967 |
| 13 | MP0008877_abnormal_DNA_methylation | 2.08975338 |
| 14 | MP0001730_embryonic_growth_arrest | 2.04814777 |
| 15 | MP0001293_anophthalmia | 2.02961465 |
| 16 | MP0003718_maternal_effect | 2.00225584 |
| 17 | MP0008932_abnormal_embryonic_tissue | 1.98084299 |
| 18 | MP0003786_premature_aging | 1.84804572 |
| 19 | MP0000350_abnormal_cell_proliferation | 1.83867194 |
| 20 | MP0003941_abnormal_skin_development | 1.72536435 |
| 21 | MP0003315_abnormal_perineum_morphology | 1.70145393 |
| 22 | MP0006035_abnormal_mitochondrial_morpho | 1.65977158 |
| 23 | MP0001188_hyperpigmentation | 1.65140384 |
| 24 | MP0005187_abnormal_penis_morphology | 1.64370638 |
| 25 | MP0006036_abnormal_mitochondrial_physio | 1.62088645 |
| 26 | MP0001697_abnormal_embryo_size | 1.56155834 |
| 27 | MP0002085_abnormal_embryonic_tissue | 1.55258189 |
| 28 | MP0009379_abnormal_foot_pigmentation | 1.54314532 |
| 29 | MP0002234_abnormal_pharynx_morphology | 1.53803636 |
| 30 | MP0006072_abnormal_retinal_apoptosis | 1.53482890 |
| 31 | MP0002938_white_spotting | 1.44777358 |
| 32 | MP0003937_abnormal_limbs/digits/tail_de | 1.42128386 |
| 33 | MP0004133_heterotaxia | 1.40025936 |
| 34 | MP0005380_embryogenesis_phenotype | 1.38810729 |
| 35 | MP0001672_abnormal_embryogenesis/_devel | 1.38810729 |
| 36 | MP0002084_abnormal_developmental_patter | 1.38689668 |
| 37 | MP0005084_abnormal_gallbladder_morpholo | 1.38663561 |
| 38 | MP0003186_abnormal_redox_activity | 1.37686888 |
| 39 | MP0000647_abnormal_sebaceous_gland | 1.36553587 |
| 40 | MP0003984_embryonic_growth_retardation | 1.35824239 |
| 41 | MP0000313_abnormal_cell_death | 1.33758537 |
| 42 | MP0002088_abnormal_embryonic_growth/wei | 1.31914635 |
| 43 | MP0002396_abnormal_hematopoietic_system | 1.29218457 |
| 44 | MP0002080_prenatal_lethality | 1.27617507 |
| 45 | MP0004808_abnormal_hematopoietic_stem | 1.25386416 |
| 46 | MP0000358_abnormal_cell_content/ | 1.23004542 |
| 47 | MP0003567_abnormal_fetal_cardiomyocyte | 1.22776523 |
| 48 | MP0000428_abnormal_craniofacial_morphol | 1.20792356 |
| 49 | MP0005174_abnormal_tail_pigmentation | 1.17306415 |
| 50 | MP0002277_abnormal_respiratory_mucosa | 1.17049289 |
| 51 | MP0000049_abnormal_middle_ear | 1.13063071 |
| 52 | MP0001286_abnormal_eye_development | 1.11957591 |
| 53 | MP0004197_abnormal_fetal_growth/weight/ | 1.11773293 |
| 54 | MP0002254_reproductive_system_inflammat | 1.10851488 |
| 55 | MP0002160_abnormal_reproductive_system | 1.01840486 |
| 56 | MP0000372_irregular_coat_pigmentation | 1.01635518 |
| 57 | MP0002653_abnormal_ependyma_morphology | 1.01261733 |
| 58 | MP0002233_abnormal_nose_morphology | 1.00481828 |
| 59 | MP0001929_abnormal_gametogenesis | 1.00390457 |
| 60 | MP0002210_abnormal_sex_determination | 1.00287056 |
| 61 | MP0000569_abnormal_digit_pigmentation | 0.98832030 |
| 62 | MP0009672_abnormal_birth_weight | 0.96546917 |
| 63 | MP0000653_abnormal_sex_gland | 0.95000827 |
| 64 | MP0008789_abnormal_olfactory_epithelium | 0.94006637 |
| 65 | MP0005253_abnormal_eye_physiology | 0.93185553 |
| 66 | MP0001145_abnormal_male_reproductive | 0.93082158 |
| 67 | MP0000678_abnormal_parathyroid_gland | 0.92527356 |
| 68 | MP0005408_hypopigmentation | 0.90016814 |
| 69 | MP0008995_early_reproductive_senescence | 0.89230808 |
| 70 | MP0001177_atelectasis | 0.87137070 |
| 71 | MP0010352_gastrointestinal_tract_polyps | 0.86227884 |
| 72 | MP0003890_abnormal_embryonic-extraembry | 0.85044117 |
| 73 | MP0003861_abnormal_nervous_system | 0.82216187 |
| 74 | MP0002111_abnormal_tail_morphology | 0.80519045 |
| 75 | MP0005391_vision/eye_phenotype | 0.80449282 |
| 76 | MP0001661_extended_life_span | 0.78512167 |
| 77 | MP0002019_abnormal_tumor_incidence | 0.78446695 |
| 78 | MP0002697_abnormal_eye_size | 0.77343063 |
| 79 | MP0000631_abnormal_neuroendocrine_gland | 0.76674791 |
| 80 | MP0002282_abnormal_trachea_morphology | 0.74993788 |
| 81 | MP0002086_abnormal_extraembryonic_tissu | 0.74939290 |
| 82 | MP0003698_abnormal_male_reproductive | 0.74228051 |
| 83 | MP0005389_reproductive_system_phenotype | 0.74078726 |
| 84 | MP0005220_abnormal_exocrine_pancreas | 0.73543404 |
| 85 | MP0001346_abnormal_lacrimal_gland | 0.73204025 |
| 86 | MP0005395_other_phenotype | 0.73104185 |
| 87 | MP0001529_abnormal_vocalization | 0.71194228 |
| 88 | MP0010030_abnormal_orbit_morphology | 0.70067306 |
| 89 | MP0000579_abnormal_nail_morphology | 0.69599087 |
| 90 | MP0003938_abnormal_ear_development | 0.69403693 |
| 91 | MP0003119_abnormal_digestive_system | 0.67816714 |
| 92 | MP0002796_impaired_skin_barrier | 0.67788938 |
| 93 | MP0001119_abnormal_female_reproductive | 0.67612174 |
| 94 | MP0002638_abnormal_pupillary_reflex | 0.67280964 |
| 95 | MP0002177_abnormal_outer_ear | 0.67122986 |
| 96 | MP0005248_abnormal_Harderian_gland | 0.64688081 |
| 97 | MP0010307_abnormal_tumor_latency | 0.64011166 |
| 98 | MP0010234_abnormal_vibrissa_follicle | 0.63656978 |
| 99 | MP0000432_abnormal_head_morphology | 0.62962046 |
| 100 | MP0003755_abnormal_palate_morphology | 0.62434316 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 4.01551868 |
| 2 | Absent/shortened dynein arms (HP:0200106) | 4.01551868 |
| 3 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.35634775 |
| 4 | Colon cancer (HP:0003003) | 3.23014661 |
| 5 | Birth length less than 3rd percentile (HP:0003561) | 3.19532930 |
| 6 | Increased hepatocellular lipid droplets (HP:0006565) | 3.18601377 |
| 7 | Supernumerary spleens (HP:0009799) | 3.17712359 |
| 8 | Abnormality of alanine metabolism (HP:0010916) | 3.11177528 |
| 9 | Hyperalaninemia (HP:0003348) | 3.11177528 |
| 10 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 3.11177528 |
| 11 | Tubulointerstitial nephritis (HP:0001970) | 3.06793704 |
| 12 | Pancreatic fibrosis (HP:0100732) | 3.05607367 |
| 13 | Lipid accumulation in hepatocytes (HP:0006561) | 3.03237200 |
| 14 | True hermaphroditism (HP:0010459) | 3.00174584 |
| 15 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.87794278 |
| 16 | Acute necrotizing encephalopathy (HP:0006965) | 2.85630820 |
| 17 | Chronic bronchitis (HP:0004469) | 2.79728545 |
| 18 | Delayed CNS myelination (HP:0002188) | 2.76230392 |
| 19 | Chromsome breakage (HP:0040012) | 2.72557466 |
| 20 | Pancreatic cysts (HP:0001737) | 2.70751628 |
| 21 | Mitochondrial inheritance (HP:0001427) | 2.63600584 |
| 22 | Acute encephalopathy (HP:0006846) | 2.59876003 |
| 23 | Volvulus (HP:0002580) | 2.54798985 |
| 24 | Increased CSF lactate (HP:0002490) | 2.54644475 |
| 25 | Abnormal ciliary motility (HP:0012262) | 2.54258606 |
| 26 | Increased serum lactate (HP:0002151) | 2.53357054 |
| 27 | Abnormality of chromosome stability (HP:0003220) | 2.50248952 |
| 28 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.48034475 |
| 29 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.48034475 |
| 30 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.46124386 |
| 31 | Congenital, generalized hypertrichosis (HP:0004540) | 2.43338677 |
| 32 | Chronic hepatic failure (HP:0100626) | 2.42529871 |
| 33 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.42505892 |
| 34 | Progressive muscle weakness (HP:0003323) | 2.41278871 |
| 35 | Increased intramyocellular lipid droplets (HP:0012240) | 2.41158497 |
| 36 | Premature ovarian failure (HP:0008209) | 2.40946685 |
| 37 | Ependymoma (HP:0002888) | 2.40516225 |
| 38 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.37275849 |
| 39 | Renal Fanconi syndrome (HP:0001994) | 2.35362151 |
| 40 | Abnormality of the labia minora (HP:0012880) | 2.33573078 |
| 41 | Median cleft lip (HP:0000161) | 2.32463761 |
| 42 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.31120617 |
| 43 | Multiple enchondromatosis (HP:0005701) | 2.29678305 |
| 44 | Pendular nystagmus (HP:0012043) | 2.27460464 |
| 45 | Progressive macrocephaly (HP:0004481) | 2.24208911 |
| 46 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.22933656 |
| 47 | Hypoplasia of the uterus (HP:0000013) | 2.22462218 |
| 48 | Abnormal biliary tract physiology (HP:0012439) | 2.21880305 |
| 49 | Bile duct proliferation (HP:0001408) | 2.21880305 |
| 50 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.20389231 |
| 51 | Abnormality of serum amino acid levels (HP:0003112) | 2.19495772 |
| 52 | Amniotic constriction ring (HP:0009775) | 2.19293557 |
| 53 | Abnormality of placental membranes (HP:0011409) | 2.19293557 |
| 54 | Hepatocellular necrosis (HP:0001404) | 2.18461144 |
| 55 | Sensory axonal neuropathy (HP:0003390) | 2.14346752 |
| 56 | Nephronophthisis (HP:0000090) | 2.12421017 |
| 57 | Reduced antithrombin III activity (HP:0001976) | 2.11090236 |
| 58 | Glioma (HP:0009733) | 2.09978216 |
| 59 | Abnormality of midbrain morphology (HP:0002418) | 2.08704428 |
| 60 | Molar tooth sign on MRI (HP:0002419) | 2.08704428 |
| 61 | Oral leukoplakia (HP:0002745) | 2.06663846 |
| 62 | Constricted visual fields (HP:0001133) | 2.06012744 |
| 63 | Septo-optic dysplasia (HP:0100842) | 2.05350561 |
| 64 | Exertional dyspnea (HP:0002875) | 2.05261993 |
| 65 | Leukodystrophy (HP:0002415) | 2.04266858 |
| 66 | Poor eye contact (HP:0000817) | 1.99910702 |
| 67 | Respiratory difficulties (HP:0002880) | 1.99395260 |
| 68 | Cystic liver disease (HP:0006706) | 1.99166326 |
| 69 | Hyperglycinemia (HP:0002154) | 1.98000016 |
| 70 | Hypergonadotropic hypogonadism (HP:0000815) | 1.96549944 |
| 71 | Cellular immunodeficiency (HP:0005374) | 1.94849390 |
| 72 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.93859196 |
| 73 | Increased muscle lipid content (HP:0009058) | 1.92717504 |
| 74 | Lactic acidosis (HP:0003128) | 1.92441281 |
| 75 | Cerebral edema (HP:0002181) | 1.91724043 |
| 76 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.91660313 |
| 77 | Rhinitis (HP:0012384) | 1.90740310 |
| 78 | Hepatic necrosis (HP:0002605) | 1.89858396 |
| 79 | Type I transferrin isoform profile (HP:0003642) | 1.87478764 |
| 80 | Anencephaly (HP:0002323) | 1.84336999 |
| 81 | Adrenal hypoplasia (HP:0000835) | 1.83584240 |
| 82 | Sparse eyelashes (HP:0000653) | 1.83417773 |
| 83 | Esophageal atresia (HP:0002032) | 1.82954489 |
| 84 | Sclerocornea (HP:0000647) | 1.82944350 |
| 85 | Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161) | 1.82029300 |
| 86 | Meckel diverticulum (HP:0002245) | 1.81911115 |
| 87 | Acute lymphatic leukemia (HP:0006721) | 1.81099019 |
| 88 | Abnormal social behavior (HP:0012433) | 1.79771500 |
| 89 | Impaired social interactions (HP:0000735) | 1.79771500 |
| 90 | Abnormal lung lobation (HP:0002101) | 1.76757107 |
| 91 | Squamous cell carcinoma (HP:0002860) | 1.76228171 |
| 92 | Small hand (HP:0200055) | 1.75674827 |
| 93 | Neoplasm of the adrenal cortex (HP:0100641) | 1.75416610 |
| 94 | Asplenia (HP:0001746) | 1.75396118 |
| 95 | Absent septum pellucidum (HP:0001331) | 1.72826367 |
| 96 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.71681296 |
| 97 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.71403454 |
| 98 | Abnormality of the ileum (HP:0001549) | 1.68832895 |
| 99 | Hyperglycinuria (HP:0003108) | 1.68560990 |
| 100 | Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376) | 1.67170637 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | CDK19 | 4.78698409 |
| 2 | MST4 | 4.43935211 |
| 3 | CDC7 | 3.55881278 |
| 4 | VRK2 | 3.26854937 |
| 5 | ZAK | 3.09269568 |
| 6 | MAP4K2 | 2.94064050 |
| 7 | MKNK1 | 2.94053245 |
| 8 | PLK2 | 2.71010998 |
| 9 | SRPK1 | 2.57024793 |
| 10 | PBK | 2.53097612 |
| 11 | SCYL2 | 2.44799641 |
| 12 | TTK | 2.25969981 |
| 13 | TAF1 | 2.21816563 |
| 14 | PLK3 | 2.11051773 |
| 15 | TNIK | 2.09147737 |
| 16 | MKNK2 | 2.06352380 |
| 17 | WNK4 | 2.05611541 |
| 18 | VRK1 | 2.03983177 |
| 19 | PLK4 | 1.96638142 |
| 20 | BRD4 | 1.93260980 |
| 21 | NEK1 | 1.90765968 |
| 22 | RPS6KA4 | 1.65531703 |
| 23 | BUB1 | 1.63288559 |
| 24 | STK16 | 1.57074122 |
| 25 | DYRK3 | 1.55071814 |
| 26 | EIF2AK1 | 1.37329778 |
| 27 | ATR | 1.36820233 |
| 28 | CDK12 | 1.36042291 |
| 29 | TLK1 | 1.33187822 |
| 30 | PLK1 | 1.32642552 |
| 31 | ALK | 1.30036848 |
| 32 | OXSR1 | 1.23468847 |
| 33 | BMPR1B | 1.22929669 |
| 34 | TSSK6 | 1.19045502 |
| 35 | AURKB | 1.11935073 |
| 36 | PRKCI | 1.10478180 |
| 37 | ACVR1B | 1.07570866 |
| 38 | WEE1 | 1.04268098 |
| 39 | CHEK2 | 0.99553764 |
| 40 | NME1 | 0.90358884 |
| 41 | CHEK1 | 0.87126266 |
| 42 | EIF2AK3 | 0.86920841 |
| 43 | ATM | 0.86855270 |
| 44 | CDK3 | 0.84496022 |
| 45 | CDK7 | 0.84422837 |
| 46 | NUAK1 | 0.82696836 |
| 47 | NEK2 | 0.81838993 |
| 48 | STK39 | 0.81582289 |
| 49 | FLT3 | 0.79776543 |
| 50 | PNCK | 0.78041978 |
| 51 | CSNK1G1 | 0.76968152 |
| 52 | CSNK1E | 0.75730702 |
| 53 | MAP3K4 | 0.72952743 |
| 54 | RPS6KB2 | 0.69928541 |
| 55 | BCR | 0.68670952 |
| 56 | CSNK1G3 | 0.66343022 |
| 57 | RPS6KA5 | 0.65686099 |
| 58 | CSNK2A2 | 0.64853197 |
| 59 | GRK1 | 0.63651693 |
| 60 | AURKA | 0.62071257 |
| 61 | CSNK1G2 | 0.59934405 |
| 62 | TGFBR1 | 0.59472755 |
| 63 | FRK | 0.58037389 |
| 64 | STK4 | 0.53761002 |
| 65 | AKT2 | 0.52706263 |
| 66 | CSNK2A1 | 0.52485714 |
| 67 | MAP2K7 | 0.51033049 |
| 68 | DAPK1 | 0.50742180 |
| 69 | CDK2 | 0.50583203 |
| 70 | TRIM28 | 0.49420636 |
| 71 | CSNK1A1L | 0.47613734 |
| 72 | STK3 | 0.47524769 |
| 73 | ADRBK2 | 0.46099846 |
| 74 | DYRK2 | 0.45578551 |
| 75 | MUSK | 0.44309887 |
| 76 | STK38L | 0.42487976 |
| 77 | CDK1 | 0.41024546 |
| 78 | CSNK1A1 | 0.40382293 |
| 79 | PRKDC | 0.37019102 |
| 80 | CCNB1 | 0.36976964 |
| 81 | MAP3K8 | 0.35941853 |
| 82 | PASK | 0.33068620 |
| 83 | ERBB4 | 0.32952558 |
| 84 | NME2 | 0.32120196 |
| 85 | CLK1 | 0.31888921 |
| 86 | INSRR | 0.29855527 |
| 87 | STK10 | 0.29618946 |
| 88 | PIK3CG | 0.29581277 |
| 89 | FGFR1 | 0.28370499 |
| 90 | PRKACB | 0.27422308 |
| 91 | PRKCE | 0.25952920 |
| 92 | PIM1 | 0.25442538 |
| 93 | CDK6 | 0.23168412 |
| 94 | MAPK13 | 0.22705248 |
| 95 | EIF2AK2 | 0.20095942 |
| 96 | WNK3 | 0.19218759 |
| 97 | CSNK1D | 0.18773618 |
| 98 | PRKD3 | 0.17381965 |
| 99 | GSK3B | 0.17141206 |
| 100 | TIE1 | 0.16923797 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA replication_Homo sapiens_hsa03030 | 4.15476402 |
| 2 | Mismatch repair_Homo sapiens_hsa03430 | 3.69897889 |
| 3 | Non-homologous end-joining_Homo sapiens_hsa03450 | 3.69452892 |
| 4 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.55014219 |
| 5 | Spliceosome_Homo sapiens_hsa03040 | 3.47397216 |
| 6 | Proteasome_Homo sapiens_hsa03050 | 3.39212611 |
| 7 | RNA polymerase_Homo sapiens_hsa03020 | 3.07809844 |
| 8 | Base excision repair_Homo sapiens_hsa03410 | 2.95226207 |
| 9 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.56676879 |
| 10 | Homologous recombination_Homo sapiens_hsa03440 | 2.49576752 |
| 11 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.48925749 |
| 12 | RNA transport_Homo sapiens_hsa03013 | 2.45563009 |
| 13 | Basal transcription factors_Homo sapiens_hsa03022 | 2.21716421 |
| 14 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.21070528 |
| 15 | Ribosome_Homo sapiens_hsa03010 | 2.18304285 |
| 16 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.12499519 |
| 17 | RNA degradation_Homo sapiens_hsa03018 | 2.08286224 |
| 18 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.07278492 |
| 19 | Cell cycle_Homo sapiens_hsa04110 | 2.02561892 |
| 20 | Protein export_Homo sapiens_hsa03060 | 2.00483395 |
| 21 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.88343644 |
| 22 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.88032153 |
| 23 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.84374694 |
| 24 | Parkinsons disease_Homo sapiens_hsa05012 | 1.78312918 |
| 25 | Huntingtons disease_Homo sapiens_hsa05016 | 1.78277527 |
| 26 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.67038237 |
| 27 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.65145116 |
| 28 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.56986710 |
| 29 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.45658064 |
| 30 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.44046850 |
| 31 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.41033563 |
| 32 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.33952318 |
| 33 | Purine metabolism_Homo sapiens_hsa00230 | 1.31453487 |
| 34 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.30512076 |
| 35 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.25298199 |
| 36 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.15335442 |
| 37 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.10949019 |
| 38 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.04884388 |
| 39 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.01046724 |
| 40 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.92943931 |
| 41 | Alzheimers disease_Homo sapiens_hsa05010 | 0.88878589 |
| 42 | Phototransduction_Homo sapiens_hsa04744 | 0.87265785 |
| 43 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.86668876 |
| 44 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.83480908 |
| 45 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.80532302 |
| 46 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.77396173 |
| 47 | Alcoholism_Homo sapiens_hsa05034 | 0.72753130 |
| 48 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.71371713 |
| 49 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.71127213 |
| 50 | Peroxisome_Homo sapiens_hsa04146 | 0.68363911 |
| 51 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.63690480 |
| 52 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.61169808 |
| 53 | Carbon metabolism_Homo sapiens_hsa01200 | 0.59678164 |
| 54 | Metabolic pathways_Homo sapiens_hsa01100 | 0.56359279 |
| 55 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.51365629 |
| 56 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.50626303 |
| 57 | Asthma_Homo sapiens_hsa05310 | 0.46110482 |
| 58 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.43932639 |
| 59 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.43836491 |
| 60 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.43287561 |
| 61 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.41674963 |
| 62 | Olfactory transduction_Homo sapiens_hsa04740 | 0.40306413 |
| 63 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.37876662 |
| 64 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.37330515 |
| 65 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.35205400 |
| 66 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.34507144 |
| 67 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.34298964 |
| 68 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.34160573 |
| 69 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.32920906 |
| 70 | Tight junction_Homo sapiens_hsa04530 | 0.32500281 |
| 71 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.32234010 |
| 72 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.31152182 |
| 73 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.30474030 |
| 74 | Thyroid cancer_Homo sapiens_hsa05216 | 0.30248074 |
| 75 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.29507772 |
| 76 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.28643697 |
| 77 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.26666464 |
| 78 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.25562145 |
| 79 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.24244331 |
| 80 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.24075151 |
| 81 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.24053496 |
| 82 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.22422188 |
| 83 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.21532677 |
| 84 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.20617790 |
| 85 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.20458340 |
| 86 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.19753281 |
| 87 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.18467543 |
| 88 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.17222923 |
| 89 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.13721573 |
| 90 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.12239024 |
| 91 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.11379038 |
| 92 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.09693692 |
| 93 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.09451903 |
| 94 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.07884249 |
| 95 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.07432035 |
| 96 | Retinol metabolism_Homo sapiens_hsa00830 | 0.07401915 |
| 97 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.07386088 |
| 98 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.06682307 |
| 99 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.06626820 |
| 100 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.05919130 |

