

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of phospholipase A2 activity (GO:0032429) | 6.67207171 |
| 2 | regulation of DNA endoreduplication (GO:0032875) | 5.76957167 |
| 3 | regulation of cholesterol esterification (GO:0010872) | 5.29254473 |
| 4 | chaperone-mediated protein transport (GO:0072321) | 4.67927434 |
| 5 | chromatin remodeling at centromere (GO:0031055) | 4.67853353 |
| 6 | rRNA modification (GO:0000154) | 4.67502974 |
| 7 | rRNA methylation (GO:0031167) | 4.39415382 |
| 8 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 4.34308673 |
| 9 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 4.33132967 |
| 10 | establishment of integrated proviral latency (GO:0075713) | 4.32032196 |
| 11 | mitochondrial calcium ion transport (GO:0006851) | 4.25657992 |
| 12 | CENP-A containing nucleosome assembly (GO:0034080) | 4.23379343 |
| 13 | positive regulation of response to oxidative stress (GO:1902884) | 4.20152144 |
| 14 | positive regulation of cellular response to oxidative stress (GO:1900409) | 4.20152144 |
| 15 | viral mRNA export from host cell nucleus (GO:0046784) | 4.11098842 |
| 16 | DNA deamination (GO:0045006) | 4.03152357 |
| 17 | DNA replication checkpoint (GO:0000076) | 3.95711880 |
| 18 | regulation of Rac protein signal transduction (GO:0035020) | 3.94906072 |
| 19 | cullin deneddylation (GO:0010388) | 3.86164768 |
| 20 | kinetochore organization (GO:0051383) | 3.77526782 |
| 21 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.76335553 |
| 22 | low-density lipoprotein particle remodeling (GO:0034374) | 3.71071496 |
| 23 | DNA double-strand break processing (GO:0000729) | 3.67780219 |
| 24 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.66211289 |
| 25 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.61856468 |
| 26 | kinetochore assembly (GO:0051382) | 3.60260247 |
| 27 | regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081) | 3.56877450 |
| 28 | protein deneddylation (GO:0000338) | 3.55642682 |
| 29 | histone exchange (GO:0043486) | 3.55235991 |
| 30 | leukotriene biosynthetic process (GO:0019370) | 3.53807220 |
| 31 | mitochondrial RNA metabolic process (GO:0000959) | 3.52614809 |
| 32 | prenylation (GO:0097354) | 3.51788408 |
| 33 | protein prenylation (GO:0018342) | 3.51788408 |
| 34 | pseudouridine synthesis (GO:0001522) | 3.50822770 |
| 35 | pyrimidine nucleotide catabolic process (GO:0006244) | 3.48779096 |
| 36 | positive regulation of macrophage derived foam cell differentiation (GO:0010744) | 3.47832891 |
| 37 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.38654207 |
| 38 | DNA replication-independent nucleosome organization (GO:0034724) | 3.38654207 |
| 39 | regulation of oxidative stress-induced neuron death (GO:1903203) | 3.34849318 |
| 40 | rRNA processing (GO:0006364) | 3.32600347 |
| 41 | establishment of viral latency (GO:0019043) | 3.29871137 |
| 42 | regulation of helicase activity (GO:0051095) | 3.29437113 |
| 43 | maturation of 5.8S rRNA (GO:0000460) | 3.28169307 |
| 44 | ncRNA catabolic process (GO:0034661) | 3.24029078 |
| 45 | mRNA cleavage (GO:0006379) | 3.23756241 |
| 46 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.23607814 |
| 47 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.19876589 |
| 48 | isotype switching (GO:0045190) | 3.19876589 |
| 49 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.19876589 |
| 50 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.18870957 |
| 51 | rRNA metabolic process (GO:0016072) | 3.18593244 |
| 52 | positive regulation of prostaglandin secretion (GO:0032308) | 3.16703819 |
| 53 | mitotic metaphase plate congression (GO:0007080) | 3.13361309 |
| 54 | transcription from mitochondrial promoter (GO:0006390) | 3.13010885 |
| 55 | L-serine metabolic process (GO:0006563) | 3.09082767 |
| 56 | ether lipid metabolic process (GO:0046485) | 3.07789794 |
| 57 | serine family amino acid biosynthetic process (GO:0009070) | 3.06862345 |
| 58 | DNA strand elongation (GO:0022616) | 2.99557438 |
| 59 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.96468307 |
| 60 | DNA ligation (GO:0006266) | 2.92574445 |
| 61 | histone mRNA metabolic process (GO:0008334) | 2.88640626 |
| 62 | negative regulation of Notch signaling pathway (GO:0045746) | 2.88516341 |
| 63 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 2.87426718 |
| 64 | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G- | 2.86120069 |
| 65 | regulation of prostaglandin secretion (GO:0032306) | 2.80980333 |
| 66 | pre-miRNA processing (GO:0031054) | 2.80538864 |
| 67 | mitotic spindle checkpoint (GO:0071174) | 2.79045791 |
| 68 | telomere maintenance via telomerase (GO:0007004) | 2.79037946 |
| 69 | tRNA modification (GO:0006400) | 2.78610721 |
| 70 | ribosome biogenesis (GO:0042254) | 2.78293221 |
| 71 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.76921128 |
| 72 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.76365524 |
| 73 | ncRNA processing (GO:0034470) | 2.74283337 |
| 74 | drinking behavior (GO:0042756) | 2.73723676 |
| 75 | ribosomal small subunit biogenesis (GO:0042274) | 2.73326614 |
| 76 | spindle checkpoint (GO:0031577) | 2.72272017 |
| 77 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.70787080 |
| 78 | rRNA transcription (GO:0009303) | 2.70572500 |
| 79 | ribosomal large subunit biogenesis (GO:0042273) | 2.67501758 |
| 80 | postreplication repair (GO:0006301) | 2.67494116 |
| 81 | heterochromatin organization (GO:0070828) | 2.67023176 |
| 82 | formation of translation preinitiation complex (GO:0001731) | 2.65599582 |
| 83 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 2.64092861 |
| 84 | resolution of meiotic recombination intermediates (GO:0000712) | 2.63618817 |
| 85 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.63588450 |
| 86 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.63588450 |
| 87 | positive regulation of uterine smooth muscle contraction (GO:0070474) | 2.62906502 |
| 88 | DNA demethylation (GO:0080111) | 2.60867682 |
| 89 | positive regulation of chromosome segregation (GO:0051984) | 2.59986600 |
| 90 | regulation of establishment of cell polarity (GO:2000114) | 2.58056876 |
| 91 | ATP synthesis coupled proton transport (GO:0015986) | 2.57836359 |
| 92 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 2.57836359 |
| 93 | protein localization to chromosome, centromeric region (GO:0071459) | 2.57708725 |
| 94 | protein targeting to mitochondrion (GO:0006626) | 2.55347631 |
| 95 | protein neddylation (GO:0045116) | 2.55019236 |
| 96 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.54143865 |
| 97 | cell differentiation involved in metanephros development (GO:0072202) | 2.54094198 |
| 98 | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:0000288) | 2.53892087 |
| 99 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 2.52432283 |
| 100 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 2.52432283 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.63973687 |
| 2 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 4.55712012 |
| 3 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 4.50015565 |
| 4 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.97030236 |
| 5 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.51537284 |
| 6 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.48692909 |
| 7 | E2F7_22180533_ChIP-Seq_HELA_Human | 3.04763869 |
| 8 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.90307358 |
| 9 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.84214222 |
| 10 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.82279843 |
| 11 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.81494885 |
| 12 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.80007143 |
| 13 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.73023952 |
| 14 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.72522846 |
| 15 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.72052499 |
| 16 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.71904378 |
| 17 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.70562833 |
| 18 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.61172902 |
| 19 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.46385936 |
| 20 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.45231287 |
| 21 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.39297107 |
| 22 | MYC_18940864_ChIP-ChIP_HL60_Human | 2.31257693 |
| 23 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 2.31134125 |
| 24 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.30606200 |
| 25 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.21736944 |
| 26 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.17700414 |
| 27 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.08961480 |
| 28 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.03220188 |
| 29 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.94991652 |
| 30 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.89245230 |
| 31 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.80759229 |
| 32 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.79952747 |
| 33 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.79919870 |
| 34 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.77502626 |
| 35 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.77021281 |
| 36 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.75365490 |
| 37 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.71884720 |
| 38 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.70626225 |
| 39 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.69933155 |
| 40 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.68832308 |
| 41 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.65451172 |
| 42 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.63688453 |
| 43 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.61935589 |
| 44 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.59553860 |
| 45 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.59383632 |
| 46 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.59253151 |
| 47 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.54213222 |
| 48 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.54133549 |
| 49 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.53181147 |
| 50 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.52847055 |
| 51 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.52726559 |
| 52 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.52726559 |
| 53 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.52726559 |
| 54 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.52572035 |
| 55 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.52322673 |
| 56 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.51304247 |
| 57 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.50401783 |
| 58 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.49500926 |
| 59 | FUS_26573619_Chip-Seq_HEK293_Human | 1.47247894 |
| 60 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.46719395 |
| 61 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.41727463 |
| 62 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.40579897 |
| 63 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.39715683 |
| 64 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.38120079 |
| 65 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.37478152 |
| 66 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 1.37270012 |
| 67 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.36375930 |
| 68 | VDR_22108803_ChIP-Seq_LS180_Human | 1.33733728 |
| 69 | EWS_26573619_Chip-Seq_HEK293_Human | 1.31721852 |
| 70 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.24104771 |
| 71 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.19033178 |
| 72 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.16946921 |
| 73 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.12711851 |
| 74 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.12192181 |
| 75 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.10402075 |
| 76 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.10382849 |
| 77 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.07462785 |
| 78 | P300_19829295_ChIP-Seq_ESCs_Human | 1.05169206 |
| 79 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.03388732 |
| 80 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.02943536 |
| 81 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.96021371 |
| 82 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.95772240 |
| 83 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.95693987 |
| 84 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 0.93422338 |
| 85 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.93169749 |
| 86 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.92643778 |
| 87 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.92643778 |
| 88 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.92367123 |
| 89 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.91659114 |
| 90 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.90943173 |
| 91 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.88586492 |
| 92 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.87966304 |
| 93 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 0.87533034 |
| 94 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.86202078 |
| 95 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 0.84673341 |
| 96 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.83765857 |
| 97 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.83604496 |
| 98 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.81762416 |
| 99 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 0.81167565 |
| 100 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.78266209 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0008057_abnormal_DNA_replication | 5.00941295 |
| 2 | MP0008007_abnormal_cellular_replicative | 4.40142648 |
| 3 | MP0003195_calcinosis | 4.11753761 |
| 4 | MP0002138_abnormal_hepatobiliary_system | 2.95548601 |
| 5 | MP0002877_abnormal_melanocyte_morpholog | 2.94273491 |
| 6 | MP0003111_abnormal_nucleus_morphology | 2.84503590 |
| 7 | MP0003786_premature_aging | 2.80128055 |
| 8 | MP0002102_abnormal_ear_morphology | 2.79953696 |
| 9 | MP0003567_abnormal_fetal_cardiomyocyte | 2.79067644 |
| 10 | MP0008058_abnormal_DNA_repair | 2.74577243 |
| 11 | MP0010094_abnormal_chromosome_stability | 2.65149359 |
| 12 | MP0003123_paternal_imprinting | 2.60713735 |
| 13 | MP0003693_abnormal_embryo_hatching | 2.46415249 |
| 14 | MP0008877_abnormal_DNA_methylation | 2.41673299 |
| 15 | MP0003315_abnormal_perineum_morphology | 2.33669681 |
| 16 | MP0003787_abnormal_imprinting | 2.25419238 |
| 17 | MP0002009_preneoplasia | 2.04981567 |
| 18 | MP0005423_abnormal_somatic_nervous | 2.00990938 |
| 19 | MP0003121_genomic_imprinting | 2.00779041 |
| 20 | MP0006072_abnormal_retinal_apoptosis | 1.96815905 |
| 21 | MP0003077_abnormal_cell_cycle | 1.81423760 |
| 22 | MP0004957_abnormal_blastocyst_morpholog | 1.81351419 |
| 23 | MP0005248_abnormal_Harderian_gland | 1.76654384 |
| 24 | MP0002796_impaired_skin_barrier | 1.75855091 |
| 25 | MP0006292_abnormal_olfactory_placode | 1.71170596 |
| 26 | MP0003941_abnormal_skin_development | 1.68292782 |
| 27 | MP0003806_abnormal_nucleotide_metabolis | 1.66692915 |
| 28 | MP0002277_abnormal_respiratory_mucosa | 1.66034434 |
| 29 | MP0006276_abnormal_autonomic_nervous | 1.64695175 |
| 30 | MP0001293_anophthalmia | 1.56388990 |
| 31 | MP0002396_abnormal_hematopoietic_system | 1.56305079 |
| 32 | MP0003119_abnormal_digestive_system | 1.55024693 |
| 33 | MP0008995_early_reproductive_senescence | 1.45064784 |
| 34 | MP0006035_abnormal_mitochondrial_morpho | 1.44723937 |
| 35 | MP0003880_abnormal_central_pattern | 1.38733233 |
| 36 | MP0009697_abnormal_copulation | 1.38105675 |
| 37 | MP0001188_hyperpigmentation | 1.37952178 |
| 38 | MP0005220_abnormal_exocrine_pancreas | 1.37036282 |
| 39 | MP0000350_abnormal_cell_proliferation | 1.31744057 |
| 40 | MP0000647_abnormal_sebaceous_gland | 1.26639226 |
| 41 | MP0002736_abnormal_nociception_after | 1.25678052 |
| 42 | MP0005379_endocrine/exocrine_gland_phen | 1.25085801 |
| 43 | MP0001270_distended_abdomen | 1.22520060 |
| 44 | MP0002837_dystrophic_cardiac_calcinosis | 1.21881631 |
| 45 | MP0000613_abnormal_salivary_gland | 1.21724772 |
| 46 | MP0002160_abnormal_reproductive_system | 1.20303144 |
| 47 | MP0004808_abnormal_hematopoietic_stem | 1.18790436 |
| 48 | MP0005084_abnormal_gallbladder_morpholo | 1.18301810 |
| 49 | MP0006036_abnormal_mitochondrial_physio | 1.17150249 |
| 50 | MP0005365_abnormal_bile_salt | 1.16853667 |
| 51 | MP0001968_abnormal_touch/_nociception | 1.14294015 |
| 52 | MP0000358_abnormal_cell_content/ | 1.13284794 |
| 53 | MP0001286_abnormal_eye_development | 1.11119606 |
| 54 | MP0002697_abnormal_eye_size | 1.09883645 |
| 55 | MP0005501_abnormal_skin_physiology | 1.08138393 |
| 56 | MP0005389_reproductive_system_phenotype | 1.05870323 |
| 57 | MP0001764_abnormal_homeostasis | 1.02447923 |
| 58 | MP0003221_abnormal_cardiomyocyte_apopto | 1.01971119 |
| 59 | MP0005193_abnormal_anterior_eye | 1.01809970 |
| 60 | MP0002928_abnormal_bile_duct | 1.01221159 |
| 61 | MP0004215_abnormal_myocardial_fiber | 1.00856388 |
| 62 | MP0003984_embryonic_growth_retardation | 0.98491622 |
| 63 | MP0005380_embryogenesis_phenotype | 0.97485514 |
| 64 | MP0001672_abnormal_embryogenesis/_devel | 0.97485514 |
| 65 | MP0003122_maternal_imprinting | 0.96474844 |
| 66 | MP0003937_abnormal_limbs/digits/tail_de | 0.96003895 |
| 67 | MP0002088_abnormal_embryonic_growth/wei | 0.95791116 |
| 68 | MP0004197_abnormal_fetal_growth/weight/ | 0.93880163 |
| 69 | MP0001730_embryonic_growth_arrest | 0.92562178 |
| 70 | MP0002132_abnormal_respiratory_system | 0.92534308 |
| 71 | MP0001919_abnormal_reproductive_system | 0.91785614 |
| 72 | MP0001145_abnormal_male_reproductive | 0.89922909 |
| 73 | MP0003186_abnormal_redox_activity | 0.85844984 |
| 74 | MP0001879_abnormal_lymphatic_vessel | 0.85257301 |
| 75 | MP0005187_abnormal_penis_morphology | 0.84955333 |
| 76 | MP0002638_abnormal_pupillary_reflex | 0.82760856 |
| 77 | MP0001984_abnormal_olfaction | 0.81939326 |
| 78 | MP0001851_eye_inflammation | 0.80342755 |
| 79 | MP0005253_abnormal_eye_physiology | 0.79013979 |
| 80 | MP0000653_abnormal_sex_gland | 0.76219379 |
| 81 | MP0010030_abnormal_orbit_morphology | 0.74082891 |
| 82 | MP0001881_abnormal_mammary_gland | 0.73900634 |
| 83 | MP0003252_abnormal_bile_duct | 0.73087616 |
| 84 | MP0005391_vision/eye_phenotype | 0.71706565 |
| 85 | MP0005670_abnormal_white_adipose | 0.71686605 |
| 86 | MP0000427_abnormal_hair_cycle | 0.71678618 |
| 87 | MP0004270_analgesia | 0.71169299 |
| 88 | MP0000313_abnormal_cell_death | 0.69942898 |
| 89 | MP0000631_abnormal_neuroendocrine_gland | 0.69132871 |
| 90 | MP0001697_abnormal_embryo_size | 0.67566346 |
| 91 | MP0002019_abnormal_tumor_incidence | 0.66938323 |
| 92 | MP0002085_abnormal_embryonic_tissue | 0.66658021 |
| 93 | MP0002166_altered_tumor_susceptibility | 0.65115698 |
| 94 | MP0001929_abnormal_gametogenesis | 0.63788653 |
| 95 | MP0002210_abnormal_sex_determination | 0.62735514 |
| 96 | MP0005408_hypopigmentation | 0.60500620 |
| 97 | MP0002177_abnormal_outer_ear | 0.60334431 |
| 98 | MP0009672_abnormal_birth_weight | 0.59668399 |
| 99 | MP0005384_cellular_phenotype | 0.59357387 |
| 100 | MP0001119_abnormal_female_reproductive | 0.59144195 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Facial shape deformation (HP:0011334) | 6.35230823 |
| 2 | Potter facies (HP:0002009) | 6.35230823 |
| 3 | Widely patent fontanelles and sutures (HP:0004492) | 5.26313102 |
| 4 | Supernumerary spleens (HP:0009799) | 3.90818706 |
| 5 | Wide cranial sutures (HP:0010537) | 3.75508698 |
| 6 | Abnormal biliary tract physiology (HP:0012439) | 3.74369036 |
| 7 | Bile duct proliferation (HP:0001408) | 3.74369036 |
| 8 | Pancreatic cysts (HP:0001737) | 3.40912781 |
| 9 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.29802900 |
| 10 | Abnormal urine output (HP:0012590) | 3.24171644 |
| 11 | Hypoplasia of the uterus (HP:0000013) | 3.20445569 |
| 12 | Multifactorial inheritance (HP:0001426) | 3.16729827 |
| 13 | Abnormality of renal excretion (HP:0011036) | 3.16292930 |
| 14 | Congenital, generalized hypertrichosis (HP:0004540) | 3.06800634 |
| 15 | Acute necrotizing encephalopathy (HP:0006965) | 2.95367208 |
| 16 | Acute encephalopathy (HP:0006846) | 2.76610615 |
| 17 | Premature ovarian failure (HP:0008209) | 2.65971652 |
| 18 | Abnormality of chromosome stability (HP:0003220) | 2.64896970 |
| 19 | Occipital encephalocele (HP:0002085) | 2.64619281 |
| 20 | True hermaphroditism (HP:0010459) | 2.62473216 |
| 21 | Hyperphosphaturia (HP:0003109) | 2.61004672 |
| 22 | Molar tooth sign on MRI (HP:0002419) | 2.60785467 |
| 23 | Abnormality of midbrain morphology (HP:0002418) | 2.60785467 |
| 24 | Pancreatic fibrosis (HP:0100732) | 2.59640677 |
| 25 | Acute lymphatic leukemia (HP:0006721) | 2.59139179 |
| 26 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.53800835 |
| 27 | Horseshoe kidney (HP:0000085) | 2.53548910 |
| 28 | Abnormal umbilical cord blood vessels (HP:0011403) | 2.50857452 |
| 29 | Single umbilical artery (HP:0001195) | 2.50857452 |
| 30 | Abnormality of the fetal cardiovascular system (HP:0010948) | 2.50857452 |
| 31 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.44864461 |
| 32 | Short tibia (HP:0005736) | 2.42515625 |
| 33 | Progressive macrocephaly (HP:0004481) | 2.38928519 |
| 34 | Abnormality of the 4th metacarpal (HP:0010012) | 2.36946522 |
| 35 | Abnormality of the preputium (HP:0100587) | 2.34507211 |
| 36 | Aplasia/Hypoplasia of the hallux (HP:0008362) | 2.34029359 |
| 37 | Neoplasm of the adrenal cortex (HP:0100641) | 2.31720692 |
| 38 | Chromsome breakage (HP:0040012) | 2.27295012 |
| 39 | Increased circulating renin level (HP:0000848) | 2.23724038 |
| 40 | Short hallux (HP:0010109) | 2.23416421 |
| 41 | Hypotension (HP:0002615) | 2.23119127 |
| 42 | Oligohydramnios (HP:0001562) | 2.22256063 |
| 43 | Cerebellar dysplasia (HP:0007033) | 2.21951718 |
| 44 | Bifid tongue (HP:0010297) | 2.20074180 |
| 45 | Cystic liver disease (HP:0006706) | 2.19827673 |
| 46 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 2.19441957 |
| 47 | Aplastic anemia (HP:0001915) | 2.18073641 |
| 48 | Abolished electroretinogram (ERG) (HP:0000550) | 2.17328427 |
| 49 | Abnormal pancreas size (HP:0012094) | 2.17260976 |
| 50 | Abnormality of the labia minora (HP:0012880) | 2.16652488 |
| 51 | Median cleft lip (HP:0000161) | 2.13727587 |
| 52 | Adrenal hypoplasia (HP:0000835) | 2.10867619 |
| 53 | Midline defect of the nose (HP:0004122) | 2.10289822 |
| 54 | Neoplasm of the adrenal gland (HP:0100631) | 2.03705720 |
| 55 | Cerebral edema (HP:0002181) | 2.03076260 |
| 56 | Cleft eyelid (HP:0000625) | 2.02112018 |
| 57 | Delayed CNS myelination (HP:0002188) | 1.98814470 |
| 58 | Bone marrow hypocellularity (HP:0005528) | 1.97317720 |
| 59 | Hypophosphatemic rickets (HP:0004912) | 1.96426748 |
| 60 | Dandy-Walker malformation (HP:0001305) | 1.94271578 |
| 61 | Pallor (HP:0000980) | 1.91912300 |
| 62 | Spinal cord lesions (HP:0100561) | 1.91647655 |
| 63 | Syringomyelia (HP:0003396) | 1.91647655 |
| 64 | Anencephaly (HP:0002323) | 1.91460051 |
| 65 | Abnormality of the umbilical cord (HP:0010881) | 1.89805638 |
| 66 | Absent eyebrow (HP:0002223) | 1.89628278 |
| 67 | Fair hair (HP:0002286) | 1.89072887 |
| 68 | Constricted visual fields (HP:0001133) | 1.88689652 |
| 69 | Abnormal urine phosphate concentration (HP:0012599) | 1.88473397 |
| 70 | Abnormal lung lobation (HP:0002101) | 1.87947383 |
| 71 | Type II lissencephaly (HP:0007260) | 1.87942181 |
| 72 | Fibular aplasia (HP:0002990) | 1.86964693 |
| 73 | Abnormality of urine glucose concentration (HP:0011016) | 1.86379589 |
| 74 | Glycosuria (HP:0003076) | 1.86379589 |
| 75 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.85432689 |
| 76 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.84651803 |
| 77 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 1.84196583 |
| 78 | Testicular atrophy (HP:0000029) | 1.82630615 |
| 79 | Pendular nystagmus (HP:0012043) | 1.80108181 |
| 80 | Abnormality of the ileum (HP:0001549) | 1.79314551 |
| 81 | Mitochondrial inheritance (HP:0001427) | 1.78267553 |
| 82 | Type I transferrin isoform profile (HP:0003642) | 1.77977635 |
| 83 | Macrocytic anemia (HP:0001972) | 1.77931626 |
| 84 | Oral leukoplakia (HP:0002745) | 1.77023537 |
| 85 | Sloping forehead (HP:0000340) | 1.75169820 |
| 86 | Abnormality of the pancreatic islet cells (HP:0006476) | 1.73602429 |
| 87 | Abnormality of endocrine pancreas physiology (HP:0012093) | 1.73602429 |
| 88 | Birth length less than 3rd percentile (HP:0003561) | 1.73109237 |
| 89 | Volvulus (HP:0002580) | 1.72679542 |
| 90 | Sclerocornea (HP:0000647) | 1.72364263 |
| 91 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 1.71170692 |
| 92 | Meckel diverticulum (HP:0002245) | 1.71011249 |
| 93 | Abnormality of secondary sexual hair (HP:0009888) | 1.68988119 |
| 94 | Abnormality of the axillary hair (HP:0100134) | 1.68988119 |
| 95 | Increased CSF lactate (HP:0002490) | 1.68941975 |
| 96 | Palpitations (HP:0001962) | 1.67014380 |
| 97 | Oculomotor apraxia (HP:0000657) | 1.64832365 |
| 98 | Chronic bronchitis (HP:0004469) | 1.64734029 |
| 99 | Cellular immunodeficiency (HP:0005374) | 1.63796734 |
| 100 | Colon cancer (HP:0003003) | 1.63716517 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ZAK | 3.60044929 |
| 2 | MAP3K6 | 3.56124996 |
| 3 | CDC7 | 2.98737938 |
| 4 | MAP3K4 | 2.89959278 |
| 5 | TAF1 | 2.86100667 |
| 6 | ACVR1B | 2.84190160 |
| 7 | PLK2 | 2.83822118 |
| 8 | VRK2 | 2.81885106 |
| 9 | MAP2K7 | 2.64864997 |
| 10 | SRPK1 | 2.41229418 |
| 11 | DAPK2 | 2.36959418 |
| 12 | BMPR1B | 2.29751117 |
| 13 | EIF2AK1 | 2.16734061 |
| 14 | VRK1 | 2.04640522 |
| 15 | MKNK2 | 2.04436619 |
| 16 | FES | 1.94922887 |
| 17 | PIK3CG | 1.91110755 |
| 18 | PLK3 | 1.84864625 |
| 19 | MST4 | 1.74438022 |
| 20 | TTK | 1.73850107 |
| 21 | DYRK3 | 1.73518462 |
| 22 | BUB1 | 1.72191873 |
| 23 | MAP2K4 | 1.70854381 |
| 24 | PLK4 | 1.66310761 |
| 25 | MAP3K14 | 1.45142756 |
| 26 | STK4 | 1.41596126 |
| 27 | MKNK1 | 1.41467521 |
| 28 | PRKCI | 1.38973814 |
| 29 | TEC | 1.38004366 |
| 30 | NEK2 | 1.36683415 |
| 31 | PLK1 | 1.34111247 |
| 32 | PBK | 1.33730144 |
| 33 | PASK | 1.32268014 |
| 34 | TLK1 | 1.25429422 |
| 35 | MAP3K5 | 1.20096309 |
| 36 | TSSK6 | 1.15901654 |
| 37 | EIF2AK3 | 1.14617590 |
| 38 | ATR | 1.09364134 |
| 39 | DAPK1 | 1.02188829 |
| 40 | DAPK3 | 1.00195749 |
| 41 | TBK1 | 0.99816336 |
| 42 | TGFBR1 | 0.99333338 |
| 43 | CHEK2 | 0.98147039 |
| 44 | CDK9 | 0.93082679 |
| 45 | STK3 | 0.92841916 |
| 46 | ITK | 0.89180241 |
| 47 | ALK | 0.88189660 |
| 48 | BLK | 0.87180905 |
| 49 | CDK6 | 0.86383187 |
| 50 | RPS6KA4 | 0.81297067 |
| 51 | BCKDK | 0.80147295 |
| 52 | CDK12 | 0.79245033 |
| 53 | GRK6 | 0.78859047 |
| 54 | AURKB | 0.77428627 |
| 55 | BTK | 0.76936254 |
| 56 | WNK4 | 0.74604786 |
| 57 | EIF2AK2 | 0.70601393 |
| 58 | NUAK1 | 0.69730929 |
| 59 | CDK3 | 0.69652852 |
| 60 | CSNK1E | 0.69549676 |
| 61 | CSNK2A2 | 0.67582213 |
| 62 | RPS6KA5 | 0.66286067 |
| 63 | DYRK2 | 0.65538947 |
| 64 | IKBKE | 0.63023990 |
| 65 | WEE1 | 0.62869363 |
| 66 | SYK | 0.62762601 |
| 67 | CHEK1 | 0.61495409 |
| 68 | FRK | 0.60120799 |
| 69 | NME1 | 0.59889553 |
| 70 | ATM | 0.59477692 |
| 71 | RPS6KB2 | 0.59300036 |
| 72 | TNIK | 0.58481625 |
| 73 | ARAF | 0.53729177 |
| 74 | MATK | 0.51784581 |
| 75 | RPS6KL1 | 0.50258020 |
| 76 | RPS6KC1 | 0.50258020 |
| 77 | STK38L | 0.50083851 |
| 78 | TXK | 0.49194116 |
| 79 | STK10 | 0.46952546 |
| 80 | RPS6KA6 | 0.46061910 |
| 81 | CSNK2A1 | 0.45994694 |
| 82 | TIE1 | 0.44966089 |
| 83 | AKT2 | 0.42599242 |
| 84 | ERN1 | 0.41871689 |
| 85 | PRKCE | 0.40490058 |
| 86 | HCK | 0.40252935 |
| 87 | ERBB4 | 0.38010804 |
| 88 | LYN | 0.37369400 |
| 89 | CDK7 | 0.37367259 |
| 90 | BRD4 | 0.36266570 |
| 91 | PRKCQ | 0.35692312 |
| 92 | CSNK1A1L | 0.35173915 |
| 93 | CSNK1G3 | 0.34770221 |
| 94 | SCYL2 | 0.33546280 |
| 95 | CSNK1G1 | 0.33101445 |
| 96 | FLT3 | 0.32060182 |
| 97 | CDK2 | 0.31508945 |
| 98 | NEK1 | 0.31228182 |
| 99 | NME2 | 0.29900160 |
| 100 | CSNK1G2 | 0.29113145 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.83763130 |
| 2 | Non-homologous end-joining_Homo sapiens_hsa03450 | 3.54660941 |
| 3 | Ribosome_Homo sapiens_hsa03010 | 3.41802958 |
| 4 | Proteasome_Homo sapiens_hsa03050 | 3.28306159 |
| 5 | RNA degradation_Homo sapiens_hsa03018 | 2.91612931 |
| 6 | Mismatch repair_Homo sapiens_hsa03430 | 2.89520080 |
| 7 | DNA replication_Homo sapiens_hsa03030 | 2.86730280 |
| 8 | Spliceosome_Homo sapiens_hsa03040 | 2.75362236 |
| 9 | Basal transcription factors_Homo sapiens_hsa03022 | 2.75078908 |
| 10 | Homologous recombination_Homo sapiens_hsa03440 | 2.64648974 |
| 11 | Renin-angiotensin system_Homo sapiens_hsa04614 | 2.53504480 |
| 12 | RNA transport_Homo sapiens_hsa03013 | 2.24938976 |
| 13 | Base excision repair_Homo sapiens_hsa03410 | 2.15993917 |
| 14 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.15175438 |
| 15 | Protein export_Homo sapiens_hsa03060 | 2.12455873 |
| 16 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.06652394 |
| 17 | RNA polymerase_Homo sapiens_hsa03020 | 2.04767149 |
| 18 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 2.00493978 |
| 19 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.98532904 |
| 20 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.98358603 |
| 21 | Parkinsons disease_Homo sapiens_hsa05012 | 1.96059449 |
| 22 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.95634305 |
| 23 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.66187912 |
| 24 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.64107695 |
| 25 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.46728716 |
| 26 | Cell cycle_Homo sapiens_hsa04110 | 1.42846724 |
| 27 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.38187298 |
| 28 | Huntingtons disease_Homo sapiens_hsa05016 | 1.36749824 |
| 29 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.29579183 |
| 30 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.17921391 |
| 31 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.16359688 |
| 32 | Asthma_Homo sapiens_hsa05310 | 1.14483214 |
| 33 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.13771414 |
| 34 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.12522824 |
| 35 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.05253191 |
| 36 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.98116239 |
| 37 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.96654620 |
| 38 | Allograft rejection_Homo sapiens_hsa05330 | 0.95683806 |
| 39 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.95638991 |
| 40 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.95627236 |
| 41 | Alzheimers disease_Homo sapiens_hsa05010 | 0.95463641 |
| 42 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.95345730 |
| 43 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.93238633 |
| 44 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.91234019 |
| 45 | Alcoholism_Homo sapiens_hsa05034 | 0.90827450 |
| 46 | Purine metabolism_Homo sapiens_hsa00230 | 0.90736500 |
| 47 | Sulfur relay system_Homo sapiens_hsa04122 | 0.87689793 |
| 48 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.86907435 |
| 49 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.83333722 |
| 50 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.79818096 |
| 51 | Peroxisome_Homo sapiens_hsa04146 | 0.74325234 |
| 52 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.74190660 |
| 53 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.71324237 |
| 54 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.67636949 |
| 55 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.66543153 |
| 56 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.64122676 |
| 57 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.63143461 |
| 58 | Thyroid cancer_Homo sapiens_hsa05216 | 0.61917805 |
| 59 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.61544626 |
| 60 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.60345086 |
| 61 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.58856706 |
| 62 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.57020003 |
| 63 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.56451925 |
| 64 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.52725619 |
| 65 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.50267261 |
| 66 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.49112093 |
| 67 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.48760185 |
| 68 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.46000847 |
| 69 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.45439162 |
| 70 | Metabolic pathways_Homo sapiens_hsa01100 | 0.38831683 |
| 71 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.38423962 |
| 72 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.37245626 |
| 73 | Melanoma_Homo sapiens_hsa05218 | 0.36848811 |
| 74 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.36801952 |
| 75 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.36410930 |
| 76 | Viral myocarditis_Homo sapiens_hsa05416 | 0.36166953 |
| 77 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.34570328 |
| 78 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.33585095 |
| 79 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.32579036 |
| 80 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.31027557 |
| 81 | Shigellosis_Homo sapiens_hsa05131 | 0.30525707 |
| 82 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.28995794 |
| 83 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.28770772 |
| 84 | Renin secretion_Homo sapiens_hsa04924 | 0.25500347 |
| 85 | Adherens junction_Homo sapiens_hsa04520 | 0.24122015 |
| 86 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.20490942 |
| 87 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.19524924 |
| 88 | Hepatitis C_Homo sapiens_hsa05160 | 0.18880966 |
| 89 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.18189274 |
| 90 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.18186826 |
| 91 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.15461957 |
| 92 | Taste transduction_Homo sapiens_hsa04742 | 0.14961149 |
| 93 | Pathways in cancer_Homo sapiens_hsa05200 | 0.14900471 |
| 94 | HTLV-I infection_Homo sapiens_hsa05166 | 0.14754604 |
| 95 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.14644477 |
| 96 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.13897613 |
| 97 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.13821208 |
| 98 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.12794852 |
| 99 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.12665211 |
| 100 | Leishmaniasis_Homo sapiens_hsa05140 | 0.12510392 |

