

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | chromatin remodeling at centromere (GO:0031055) | 5.34076650 |
| 2 | CENP-A containing nucleosome assembly (GO:0034080) | 5.30580600 |
| 3 | establishment of integrated proviral latency (GO:0075713) | 5.21274166 |
| 4 | regulation of translational termination (GO:0006449) | 4.75931429 |
| 5 | water-soluble vitamin biosynthetic process (GO:0042364) | 4.75813058 |
| 6 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.58892093 |
| 7 | histone exchange (GO:0043486) | 4.40609277 |
| 8 | DNA strand elongation (GO:0022616) | 4.37733646 |
| 9 | L-serine metabolic process (GO:0006563) | 4.27250799 |
| 10 | DNA double-strand break processing (GO:0000729) | 4.25775746 |
| 11 | DNA damage response, detection of DNA damage (GO:0042769) | 4.23627469 |
| 12 | IMP biosynthetic process (GO:0006188) | 4.23567078 |
| 13 | DNA ligation (GO:0006266) | 4.18883045 |
| 14 | establishment of viral latency (GO:0019043) | 4.11769973 |
| 15 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.95624749 |
| 16 | DNA replication-independent nucleosome organization (GO:0034724) | 3.95624749 |
| 17 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.87690970 |
| 18 | IMP metabolic process (GO:0046040) | 3.84738707 |
| 19 | positive regulation of male gonad development (GO:2000020) | 3.84344705 |
| 20 | mitotic metaphase plate congression (GO:0007080) | 3.83183229 |
| 21 | cullin deneddylation (GO:0010388) | 3.83085671 |
| 22 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 3.81342339 |
| 23 | negative regulation of sister chromatid segregation (GO:0033046) | 3.81342339 |
| 24 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 3.81342339 |
| 25 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 3.81342339 |
| 26 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 3.81342339 |
| 27 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.76985513 |
| 28 | negative regulation of chromosome segregation (GO:0051985) | 3.75414358 |
| 29 | protein localization to kinetochore (GO:0034501) | 3.75060706 |
| 30 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.73534631 |
| 31 | non-recombinational repair (GO:0000726) | 3.73534631 |
| 32 | replication fork processing (GO:0031297) | 3.65216987 |
| 33 | protein deneddylation (GO:0000338) | 3.65012203 |
| 34 | negative regulation of DNA recombination (GO:0045910) | 3.64534120 |
| 35 | spindle checkpoint (GO:0031577) | 3.63244061 |
| 36 | ribosome assembly (GO:0042255) | 3.62812034 |
| 37 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.60601179 |
| 38 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.60601179 |
| 39 | mitotic spindle checkpoint (GO:0071174) | 3.58749902 |
| 40 | DNA replication checkpoint (GO:0000076) | 3.56817141 |
| 41 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.51016624 |
| 42 | proteasome assembly (GO:0043248) | 3.50824823 |
| 43 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.46022711 |
| 44 | telomere maintenance via recombination (GO:0000722) | 3.42870830 |
| 45 | purine nucleobase biosynthetic process (GO:0009113) | 3.41209245 |
| 46 | metaphase plate congression (GO:0051310) | 3.41202537 |
| 47 | mitotic spindle assembly checkpoint (GO:0007094) | 3.40400758 |
| 48 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.40061090 |
| 49 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.39594234 |
| 50 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.39594234 |
| 51 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 3.38664392 |
| 52 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 3.38664392 |
| 53 | mitotic recombination (GO:0006312) | 3.37894860 |
| 54 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.37257503 |
| 55 | mitotic sister chromatid segregation (GO:0000070) | 3.36438844 |
| 56 | spindle assembly checkpoint (GO:0071173) | 3.34811255 |
| 57 | negative regulation of mitosis (GO:0045839) | 3.34676347 |
| 58 | histone H2A acetylation (GO:0043968) | 3.32159321 |
| 59 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.31912149 |
| 60 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.31912149 |
| 61 | regulation of mitotic sister chromatid separation (GO:0010965) | 3.28884169 |
| 62 | regulation of mitotic sister chromatid segregation (GO:0033047) | 3.28884169 |
| 63 | regulation of sister chromatid segregation (GO:0033045) | 3.28884169 |
| 64 | response to pheromone (GO:0019236) | 3.28745137 |
| 65 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.28620479 |
| 66 | DNA unwinding involved in DNA replication (GO:0006268) | 3.28619590 |
| 67 | DNA replication initiation (GO:0006270) | 3.26728599 |
| 68 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.25888424 |
| 69 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.24402958 |
| 70 | regulation of chromosome segregation (GO:0051983) | 3.22377048 |
| 71 | rRNA modification (GO:0000154) | 3.22104169 |
| 72 | tRNA methylation (GO:0030488) | 3.20852078 |
| 73 | nucleobase biosynthetic process (GO:0046112) | 3.18731835 |
| 74 | regulation of centriole replication (GO:0046599) | 3.17790910 |
| 75 | histone mRNA metabolic process (GO:0008334) | 3.17620773 |
| 76 | negative regulation of ligase activity (GO:0051352) | 3.16371841 |
| 77 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.16371841 |
| 78 | DNA strand renaturation (GO:0000733) | 3.15361628 |
| 79 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.14634246 |
| 80 | pseudouridine synthesis (GO:0001522) | 3.14413356 |
| 81 | regulation of helicase activity (GO:0051095) | 3.12427843 |
| 82 | regulation of male gonad development (GO:2000018) | 3.12078454 |
| 83 | telomere maintenance via telomere lengthening (GO:0010833) | 3.09121989 |
| 84 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.08932142 |
| 85 | cell fate commitment involved in formation of primary germ layer (GO:0060795) | 3.08904531 |
| 86 | chromatin assembly or disassembly (GO:0006333) | 3.07678576 |
| 87 | telomere maintenance via telomerase (GO:0007004) | 3.06612587 |
| 88 | sister chromatid segregation (GO:0000819) | 3.05009070 |
| 89 | attachment of spindle microtubules to kinetochore (GO:0008608) | 3.02881377 |
| 90 | establishment of chromosome localization (GO:0051303) | 3.00064910 |
| 91 | RNA-dependent DNA replication (GO:0006278) | 2.99966284 |
| 92 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 2.99133091 |
| 93 | recombinational repair (GO:0000725) | 2.99042107 |
| 94 | negative regulation of nuclear division (GO:0051784) | 2.98312665 |
| 95 | double-strand break repair via homologous recombination (GO:0000724) | 2.97660836 |
| 96 | DNA-dependent DNA replication (GO:0006261) | 2.97444063 |
| 97 | protein localization to chromosome, centromeric region (GO:0071459) | 2.96678985 |
| 98 | telomere maintenance (GO:0000723) | 2.94856374 |
| 99 | ATP-dependent chromatin remodeling (GO:0043044) | 2.94238226 |
| 100 | telomere organization (GO:0032200) | 2.93191718 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 7.08770327 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.60077550 |
| 3 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 4.39078805 |
| 4 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 4.14146819 |
| 5 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 3.62699759 |
| 6 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.61526103 |
| 7 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.47989937 |
| 8 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.09998336 |
| 9 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 3.00910383 |
| 10 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.92864911 |
| 11 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.88562455 |
| 12 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.67238585 |
| 13 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.63092562 |
| 14 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.56879109 |
| 15 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.51884220 |
| 16 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.51715605 |
| 17 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.51349576 |
| 18 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.39874817 |
| 19 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.39251142 |
| 20 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.36194713 |
| 21 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.32675941 |
| 22 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.22332133 |
| 23 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 2.15919873 |
| 24 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.14048315 |
| 25 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.09638271 |
| 26 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.08881943 |
| 27 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 2.08050224 |
| 28 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.06213922 |
| 29 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.99436884 |
| 30 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.94760952 |
| 31 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.91747956 |
| 32 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.91050527 |
| 33 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.89132436 |
| 34 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.86170705 |
| 35 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.86138105 |
| 36 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.83052769 |
| 37 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.81954579 |
| 38 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.81053316 |
| 39 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.78970365 |
| 40 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.75361759 |
| 41 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.74411499 |
| 42 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.69833002 |
| 43 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.69680464 |
| 44 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.69477795 |
| 45 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.68855784 |
| 46 | EWS_26573619_Chip-Seq_HEK293_Human | 1.66705209 |
| 47 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.58639240 |
| 48 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.58416382 |
| 49 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.55336491 |
| 50 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.55057469 |
| 51 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.50671792 |
| 52 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.46373828 |
| 53 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.46303622 |
| 54 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.44391833 |
| 55 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.43931720 |
| 56 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.42771977 |
| 57 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.34149216 |
| 58 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.26929733 |
| 59 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.24796662 |
| 60 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.23184695 |
| 61 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.21667865 |
| 62 | VDR_22108803_ChIP-Seq_LS180_Human | 1.21426044 |
| 63 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.19691581 |
| 64 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.17173863 |
| 65 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 1.15398725 |
| 66 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.09651129 |
| 67 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.08643746 |
| 68 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.07472808 |
| 69 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.07319999 |
| 70 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.06285704 |
| 71 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.02457682 |
| 72 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 0.97438200 |
| 73 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.97199431 |
| 74 | FUS_26573619_Chip-Seq_HEK293_Human | 0.95311948 |
| 75 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.94717426 |
| 76 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.93790020 |
| 77 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.90940001 |
| 78 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 0.90183180 |
| 79 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 0.89032292 |
| 80 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.86525373 |
| 81 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 0.85965530 |
| 82 | TBX3_20139965_ChIP-Seq_ESCs_Mouse | 0.85291197 |
| 83 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 0.84262440 |
| 84 | TBX3_20139965_ChIP-Seq_MESCs_Mouse | 0.84162828 |
| 85 | P300_19829295_ChIP-Seq_ESCs_Human | 0.82734534 |
| 86 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 0.81426783 |
| 87 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.80558010 |
| 88 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.79795234 |
| 89 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 0.79122940 |
| 90 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.78366601 |
| 91 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.76921433 |
| 92 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.76413145 |
| 93 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.72875248 |
| 94 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.72364705 |
| 95 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.71453625 |
| 96 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.71369421 |
| 97 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.70691622 |
| 98 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 0.70130290 |
| 99 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.70042941 |
| 100 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.69503641 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003693_abnormal_embryo_hatching | 5.19979878 |
| 2 | MP0010094_abnormal_chromosome_stability | 5.08090286 |
| 3 | MP0008058_abnormal_DNA_repair | 4.51350675 |
| 4 | MP0004957_abnormal_blastocyst_morpholog | 4.26220983 |
| 5 | MP0003111_abnormal_nucleus_morphology | 4.14982073 |
| 6 | MP0003077_abnormal_cell_cycle | 3.10287247 |
| 7 | MP0008932_abnormal_embryonic_tissue | 2.87454543 |
| 8 | MP0001529_abnormal_vocalization | 2.70351420 |
| 9 | MP0008007_abnormal_cellular_replicative | 2.51589104 |
| 10 | MP0002102_abnormal_ear_morphology | 2.50502405 |
| 11 | MP0008057_abnormal_DNA_replication | 2.43757909 |
| 12 | MP0008877_abnormal_DNA_methylation | 2.39595734 |
| 13 | MP0003718_maternal_effect | 2.37879744 |
| 14 | MP0006035_abnormal_mitochondrial_morpho | 2.37791478 |
| 15 | MP0003890_abnormal_embryonic-extraembry | 2.15369246 |
| 16 | MP0003786_premature_aging | 2.09293781 |
| 17 | MP0009697_abnormal_copulation | 2.07095543 |
| 18 | MP0003941_abnormal_skin_development | 2.06733372 |
| 19 | MP0006292_abnormal_olfactory_placode | 1.98987576 |
| 20 | MP0001293_anophthalmia | 1.87097206 |
| 21 | MP0002751_abnormal_autonomic_nervous | 1.80642722 |
| 22 | MP0010352_gastrointestinal_tract_polyps | 1.79204691 |
| 23 | MP0008789_abnormal_olfactory_epithelium | 1.76977592 |
| 24 | MP0000566_synostosis | 1.68330249 |
| 25 | MP0001730_embryonic_growth_arrest | 1.63233027 |
| 26 | MP0003119_abnormal_digestive_system | 1.60766379 |
| 27 | MP0000350_abnormal_cell_proliferation | 1.57996037 |
| 28 | MP0009672_abnormal_birth_weight | 1.52583567 |
| 29 | MP0003121_genomic_imprinting | 1.45689669 |
| 30 | MP0003123_paternal_imprinting | 1.44413064 |
| 31 | MP0005394_taste/olfaction_phenotype | 1.43979891 |
| 32 | MP0005499_abnormal_olfactory_system | 1.43979891 |
| 33 | MP0001672_abnormal_embryogenesis/_devel | 1.39508807 |
| 34 | MP0005380_embryogenesis_phenotype | 1.39508807 |
| 35 | MP0001727_abnormal_embryo_implantation | 1.37935291 |
| 36 | MP0002085_abnormal_embryonic_tissue | 1.37309573 |
| 37 | MP0006072_abnormal_retinal_apoptosis | 1.37215703 |
| 38 | MP0000490_abnormal_crypts_of | 1.36894386 |
| 39 | MP0003806_abnormal_nucleotide_metabolis | 1.35676098 |
| 40 | MP0000647_abnormal_sebaceous_gland | 1.35628750 |
| 41 | MP0001697_abnormal_embryo_size | 1.34480044 |
| 42 | MP0000358_abnormal_cell_content/ | 1.32419880 |
| 43 | MP0006036_abnormal_mitochondrial_physio | 1.30289075 |
| 44 | MP0002254_reproductive_system_inflammat | 1.30225670 |
| 45 | MP0002736_abnormal_nociception_after | 1.25785622 |
| 46 | MP0001188_hyperpigmentation | 1.20979962 |
| 47 | MP0003984_embryonic_growth_retardation | 1.17141302 |
| 48 | MP0003567_abnormal_fetal_cardiomyocyte | 1.16525332 |
| 49 | MP0002080_prenatal_lethality | 1.16225773 |
| 50 | MP0004742_abnormal_vestibular_system | 1.16070578 |
| 51 | MP0002088_abnormal_embryonic_growth/wei | 1.15465968 |
| 52 | MP0002084_abnormal_developmental_patter | 1.14215597 |
| 53 | MP0003122_maternal_imprinting | 1.13895810 |
| 54 | MP0010307_abnormal_tumor_latency | 1.12535227 |
| 55 | MP0002938_white_spotting | 1.11302511 |
| 56 | MP0004197_abnormal_fetal_growth/weight/ | 1.09958170 |
| 57 | MP0005187_abnormal_penis_morphology | 1.06714711 |
| 58 | MP0002210_abnormal_sex_determination | 1.03625787 |
| 59 | MP0002396_abnormal_hematopoietic_system | 1.03615605 |
| 60 | MP0000313_abnormal_cell_death | 1.02036298 |
| 61 | MP0001485_abnormal_pinna_reflex | 0.99968541 |
| 62 | MP0001984_abnormal_olfaction | 0.97307187 |
| 63 | MP0004782_abnormal_surfactant_physiolog | 0.97175431 |
| 64 | MP0003937_abnormal_limbs/digits/tail_de | 0.96732173 |
| 65 | MP0001346_abnormal_lacrimal_gland | 0.94047141 |
| 66 | MP0001286_abnormal_eye_development | 0.91028970 |
| 67 | MP0001929_abnormal_gametogenesis | 0.88995979 |
| 68 | MP0002086_abnormal_extraembryonic_tissu | 0.85552241 |
| 69 | MP0003880_abnormal_central_pattern | 0.85295893 |
| 70 | MP0003787_abnormal_imprinting | 0.84478344 |
| 71 | MP0009703_decreased_birth_body | 0.84159304 |
| 72 | MP0001145_abnormal_male_reproductive | 0.82579739 |
| 73 | MP0000653_abnormal_sex_gland | 0.82344817 |
| 74 | MP0002111_abnormal_tail_morphology | 0.79945547 |
| 75 | MP0010030_abnormal_orbit_morphology | 0.79690959 |
| 76 | MP0005253_abnormal_eye_physiology | 0.79177632 |
| 77 | MP0002697_abnormal_eye_size | 0.76080505 |
| 78 | MP0000383_abnormal_hair_follicle | 0.75042406 |
| 79 | MP0002019_abnormal_tumor_incidence | 0.74166343 |
| 80 | MP0003861_abnormal_nervous_system | 0.72041901 |
| 81 | MP0000537_abnormal_urethra_morphology | 0.72009252 |
| 82 | MP0004147_increased_porphyrin_level | 0.69585034 |
| 83 | MP0003315_abnormal_perineum_morphology | 0.69552459 |
| 84 | MP0008873_increased_physiological_sensi | 0.69180151 |
| 85 | MP0000427_abnormal_hair_cycle | 0.68607289 |
| 86 | MP0003936_abnormal_reproductive_system | 0.66786791 |
| 87 | MP0005391_vision/eye_phenotype | 0.65941028 |
| 88 | MP0001119_abnormal_female_reproductive | 0.64651870 |
| 89 | MP0008770_decreased_survivor_rate | 0.63075414 |
| 90 | MP0001177_atelectasis | 0.61565109 |
| 91 | MP0001968_abnormal_touch/_nociception | 0.61213715 |
| 92 | MP0003942_abnormal_urinary_system | 0.61073098 |
| 93 | MP0005395_other_phenotype | 0.60912023 |
| 94 | MP0002233_abnormal_nose_morphology | 0.59908286 |
| 95 | MP0000579_abnormal_nail_morphology | 0.58978819 |
| 96 | MP0002796_impaired_skin_barrier | 0.58943392 |
| 97 | MP0001299_abnormal_eye_distance/ | 0.58597925 |
| 98 | MP0002160_abnormal_reproductive_system | 0.58144451 |
| 99 | MP0005384_cellular_phenotype | 0.57583556 |
| 100 | MP0000631_abnormal_neuroendocrine_gland | 0.57398694 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Abnormality of the labia minora (HP:0012880) | 4.49160211 |
| 2 | Methylmalonic acidemia (HP:0002912) | 4.14551619 |
| 3 | Colon cancer (HP:0003003) | 3.94319215 |
| 4 | Hyperglycinemia (HP:0002154) | 3.52730923 |
| 5 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 3.37885021 |
| 6 | Methylmalonic aciduria (HP:0012120) | 3.36941417 |
| 7 | Ependymoma (HP:0002888) | 3.34687825 |
| 8 | Abnormality of serum amino acid levels (HP:0003112) | 3.32029088 |
| 9 | Abnormal lung lobation (HP:0002101) | 3.24411205 |
| 10 | Homocystinuria (HP:0002156) | 3.23903823 |
| 11 | Abnormality of homocysteine metabolism (HP:0010919) | 3.23903823 |
| 12 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 3.14267227 |
| 13 | Abnormality of alanine metabolism (HP:0010916) | 3.14267227 |
| 14 | Hyperalaninemia (HP:0003348) | 3.14267227 |
| 15 | Abnormality of methionine metabolism (HP:0010901) | 3.13588594 |
| 16 | Nephroblastoma (Wilms tumor) (HP:0002667) | 3.05394106 |
| 17 | Meckel diverticulum (HP:0002245) | 3.04002429 |
| 18 | Abnormality of the ileum (HP:0001549) | 3.01733361 |
| 19 | Abnormality of chromosome stability (HP:0003220) | 2.98268854 |
| 20 | Embryonal renal neoplasm (HP:0011794) | 2.87963636 |
| 21 | Abnormal hair whorl (HP:0010721) | 2.87826020 |
| 22 | Chromsome breakage (HP:0040012) | 2.87800695 |
| 23 | Birth length less than 3rd percentile (HP:0003561) | 2.82383213 |
| 24 | Abnormality of the preputium (HP:0100587) | 2.80714112 |
| 25 | Agnosia (HP:0010524) | 2.71008382 |
| 26 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.61745806 |
| 27 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.60559396 |
| 28 | Ectopic kidney (HP:0000086) | 2.59988968 |
| 29 | Acute necrotizing encephalopathy (HP:0006965) | 2.59758799 |
| 30 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.58750092 |
| 31 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.52550498 |
| 32 | Abnormality of glycine metabolism (HP:0010895) | 2.52550498 |
| 33 | Acute encephalopathy (HP:0006846) | 2.49403687 |
| 34 | Pancreatic islet-cell hyperplasia (HP:0004510) | 2.48577317 |
| 35 | Rhabdomyosarcoma (HP:0002859) | 2.47032004 |
| 36 | Small intestinal stenosis (HP:0012848) | 2.41405717 |
| 37 | Duodenal stenosis (HP:0100867) | 2.41405717 |
| 38 | Increased CSF lactate (HP:0002490) | 2.39969698 |
| 39 | Congenital, generalized hypertrichosis (HP:0004540) | 2.39144325 |
| 40 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 2.33857004 |
| 41 | Glioma (HP:0009733) | 2.33493027 |
| 42 | Abnormality of vitamin B metabolism (HP:0004340) | 2.33448854 |
| 43 | Abnormality of the duodenum (HP:0002246) | 2.30542225 |
| 44 | Septo-optic dysplasia (HP:0100842) | 2.29169757 |
| 45 | Increased hepatocellular lipid droplets (HP:0006565) | 2.27778363 |
| 46 | Cerebral hypomyelination (HP:0006808) | 2.24887842 |
| 47 | True hermaphroditism (HP:0010459) | 2.23902310 |
| 48 | Horseshoe kidney (HP:0000085) | 2.19504532 |
| 49 | Megaloblastic anemia (HP:0001889) | 2.18680573 |
| 50 | Astrocytoma (HP:0009592) | 2.17992486 |
| 51 | Abnormality of the astrocytes (HP:0100707) | 2.17992486 |
| 52 | Progressive macrocephaly (HP:0004481) | 2.16061851 |
| 53 | Hyperglycinuria (HP:0003108) | 2.16043199 |
| 54 | Medulloblastoma (HP:0002885) | 2.14535007 |
| 55 | Nausea (HP:0002018) | 2.14506075 |
| 56 | Sloping forehead (HP:0000340) | 2.12471714 |
| 57 | Adrenal hypoplasia (HP:0000835) | 2.07801093 |
| 58 | Abnormality of glycolysis (HP:0004366) | 2.07350654 |
| 59 | Breast aplasia (HP:0100783) | 2.06920859 |
| 60 | Triphalangeal thumb (HP:0001199) | 2.04837833 |
| 61 | Pendular nystagmus (HP:0012043) | 2.03731185 |
| 62 | Hypothermia (HP:0002045) | 2.00532094 |
| 63 | Mitochondrial inheritance (HP:0001427) | 2.00443411 |
| 64 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.00364967 |
| 65 | Increased serum lactate (HP:0002151) | 2.00254749 |
| 66 | Lipid accumulation in hepatocytes (HP:0006561) | 1.99623234 |
| 67 | Hypoplastic pelvis (HP:0008839) | 1.99525939 |
| 68 | Aplasia involving forearm bones (HP:0009822) | 1.99157504 |
| 69 | Absent forearm bone (HP:0003953) | 1.99157504 |
| 70 | Increased serum pyruvate (HP:0003542) | 1.99027678 |
| 71 | Patellar aplasia (HP:0006443) | 1.97678757 |
| 72 | Cerebral edema (HP:0002181) | 1.97286887 |
| 73 | Limb hypertonia (HP:0002509) | 1.94502298 |
| 74 | Generalized aminoaciduria (HP:0002909) | 1.93779776 |
| 75 | Absent radius (HP:0003974) | 1.91086676 |
| 76 | Neoplasm of the colon (HP:0100273) | 1.90542735 |
| 77 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.88218401 |
| 78 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.88218401 |
| 79 | Hypoplasia of the pons (HP:0012110) | 1.85036426 |
| 80 | Aplasia/Hypoplasia of the breasts (HP:0010311) | 1.84696586 |
| 81 | 3-Methylglutaconic aciduria (HP:0003535) | 1.84061659 |
| 82 | Aplasia/Hypoplasia of the patella (HP:0006498) | 1.82607501 |
| 83 | Neoplasm of the pancreas (HP:0002894) | 1.82374185 |
| 84 | Myelodysplasia (HP:0002863) | 1.82243108 |
| 85 | Absent septum pellucidum (HP:0001331) | 1.81808408 |
| 86 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.80978542 |
| 87 | Ovarian neoplasm (HP:0100615) | 1.80359423 |
| 88 | Lactic acidosis (HP:0003128) | 1.79922639 |
| 89 | Small hand (HP:0200055) | 1.79710175 |
| 90 | Clubbing of toes (HP:0100760) | 1.78529848 |
| 91 | Prostate neoplasm (HP:0100787) | 1.78125306 |
| 92 | Overlapping toe (HP:0001845) | 1.77556591 |
| 93 | Renal Fanconi syndrome (HP:0001994) | 1.76095038 |
| 94 | Primary amenorrhea (HP:0000786) | 1.75319921 |
| 95 | Inability to walk (HP:0002540) | 1.74734397 |
| 96 | Hepatocellular necrosis (HP:0001404) | 1.74588282 |
| 97 | Bifid tongue (HP:0010297) | 1.74336975 |
| 98 | Secondary amenorrhea (HP:0000869) | 1.72800373 |
| 99 | Micronodular cirrhosis (HP:0001413) | 1.72269463 |
| 100 | Hepatic necrosis (HP:0002605) | 1.72186012 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TSSK6 | 4.09747898 |
| 2 | VRK2 | 4.08714068 |
| 3 | ZAK | 3.94200780 |
| 4 | BUB1 | 3.69978328 |
| 5 | VRK1 | 3.18198473 |
| 6 | TNIK | 2.78066153 |
| 7 | PLK3 | 2.67308940 |
| 8 | MKNK2 | 2.66277805 |
| 9 | WNK3 | 2.61646977 |
| 10 | TLK1 | 2.54260227 |
| 11 | CDC7 | 2.51394959 |
| 12 | MKNK1 | 2.50239224 |
| 13 | TAF1 | 2.42987651 |
| 14 | TTK | 2.39383159 |
| 15 | SRPK1 | 2.18991773 |
| 16 | PBK | 2.17250520 |
| 17 | NUAK1 | 2.06333094 |
| 18 | PDK2 | 2.04314143 |
| 19 | NEK1 | 2.02651802 |
| 20 | EIF2AK3 | 1.92151947 |
| 21 | BMPR1B | 1.89565287 |
| 22 | MST4 | 1.79880927 |
| 23 | STK16 | 1.78075270 |
| 24 | PLK4 | 1.75537614 |
| 25 | PLK1 | 1.62267438 |
| 26 | WEE1 | 1.51997322 |
| 27 | EIF2AK1 | 1.46003115 |
| 28 | CCNB1 | 1.29305153 |
| 29 | CSNK1G1 | 1.22689318 |
| 30 | CSNK1G3 | 1.22167929 |
| 31 | CHEK2 | 1.18415076 |
| 32 | CSNK1G2 | 1.17445360 |
| 33 | ATR | 1.16139499 |
| 34 | TRIM28 | 1.13789240 |
| 35 | ACVR1B | 1.13362334 |
| 36 | TGFBR1 | 1.12633340 |
| 37 | BRSK2 | 1.10782467 |
| 38 | SMG1 | 1.06641074 |
| 39 | OXSR1 | 1.04620585 |
| 40 | ERBB3 | 0.96608581 |
| 41 | NLK | 0.96206458 |
| 42 | NME1 | 0.95556376 |
| 43 | BCKDK | 0.93856949 |
| 44 | PASK | 0.92270015 |
| 45 | NEK2 | 0.89197994 |
| 46 | STK39 | 0.87831902 |
| 47 | AURKB | 0.85908614 |
| 48 | MELK | 0.84616084 |
| 49 | MAP3K12 | 0.83498519 |
| 50 | DYRK2 | 0.81192349 |
| 51 | CSNK1A1L | 0.80036618 |
| 52 | PAK4 | 0.77701234 |
| 53 | BCR | 0.76070855 |
| 54 | EIF2AK2 | 0.75900597 |
| 55 | ATM | 0.75556870 |
| 56 | ALK | 0.74848788 |
| 57 | AURKA | 0.73203628 |
| 58 | STK4 | 0.72803951 |
| 59 | TAOK3 | 0.71308206 |
| 60 | STK3 | 0.64468205 |
| 61 | CDK7 | 0.59137560 |
| 62 | CHEK1 | 0.58843526 |
| 63 | PNCK | 0.58313471 |
| 64 | DAPK1 | 0.58194964 |
| 65 | ADRBK2 | 0.55512632 |
| 66 | DAPK3 | 0.54289077 |
| 67 | RPS6KA5 | 0.54092437 |
| 68 | RPS6KA4 | 0.53171034 |
| 69 | CSNK1E | 0.52673535 |
| 70 | GRK1 | 0.49325027 |
| 71 | NME2 | 0.49178640 |
| 72 | CSNK2A1 | 0.48335550 |
| 73 | DYRK3 | 0.47991346 |
| 74 | CLK1 | 0.43771288 |
| 75 | PRKCE | 0.43334334 |
| 76 | CDK6 | 0.42696166 |
| 77 | FGFR2 | 0.42068759 |
| 78 | BRSK1 | 0.41229154 |
| 79 | CSNK2A2 | 0.39814933 |
| 80 | STK38L | 0.37882983 |
| 81 | CDK2 | 0.35763950 |
| 82 | TEC | 0.35749898 |
| 83 | BRAF | 0.34872847 |
| 84 | CDK9 | 0.34347909 |
| 85 | CAMK1D | 0.32402480 |
| 86 | CSNK1A1 | 0.30025538 |
| 87 | CDK1 | 0.29507451 |
| 88 | FGFR1 | 0.27548790 |
| 89 | MAP3K8 | 0.24987952 |
| 90 | GSK3A | 0.22602588 |
| 91 | CDK18 | 0.21464485 |
| 92 | PIM1 | 0.20976111 |
| 93 | NEK9 | 0.19208369 |
| 94 | BRD4 | 0.18280999 |
| 95 | CDK15 | 0.18114518 |
| 96 | CSNK1D | 0.18008140 |
| 97 | PRKDC | 0.17177178 |
| 98 | CDK14 | 0.17031909 |
| 99 | CDK11A | 0.16036424 |
| 100 | PRKCG | 0.15266661 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 3.97894759 |
| 2 | Mismatch repair_Homo sapiens_hsa03430 | 3.91397459 |
| 3 | DNA replication_Homo sapiens_hsa03030 | 3.89167724 |
| 4 | Non-homologous end-joining_Homo sapiens_hsa03450 | 3.31724372 |
| 5 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.96555221 |
| 6 | Homologous recombination_Homo sapiens_hsa03440 | 2.90414132 |
| 7 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.68130992 |
| 8 | Spliceosome_Homo sapiens_hsa03040 | 2.55905733 |
| 9 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.51244025 |
| 10 | RNA degradation_Homo sapiens_hsa03018 | 2.37742749 |
| 11 | Protein export_Homo sapiens_hsa03060 | 2.37134944 |
| 12 | RNA transport_Homo sapiens_hsa03013 | 2.34110409 |
| 13 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 2.32057646 |
| 14 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.30857485 |
| 15 | Basal transcription factors_Homo sapiens_hsa03022 | 2.28490849 |
| 16 | Cell cycle_Homo sapiens_hsa04110 | 2.18485571 |
| 17 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.13905970 |
| 18 | RNA polymerase_Homo sapiens_hsa03020 | 2.10759854 |
| 19 | Base excision repair_Homo sapiens_hsa03410 | 2.09024346 |
| 20 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.95530540 |
| 21 | Parkinsons disease_Homo sapiens_hsa05012 | 1.78838331 |
| 22 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.78818741 |
| 23 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.68119599 |
| 24 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.64396502 |
| 25 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.63706475 |
| 26 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.63614913 |
| 27 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.56023896 |
| 28 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.55827806 |
| 29 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.52551546 |
| 30 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.51292036 |
| 31 | Ribosome_Homo sapiens_hsa03010 | 1.42228134 |
| 32 | Alcoholism_Homo sapiens_hsa05034 | 1.41254502 |
| 33 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.40570329 |
| 34 | Huntingtons disease_Homo sapiens_hsa05016 | 1.36865400 |
| 35 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.28840269 |
| 36 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.18687309 |
| 37 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.16929006 |
| 38 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.15296718 |
| 39 | Purine metabolism_Homo sapiens_hsa00230 | 1.10656668 |
| 40 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.09213332 |
| 41 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.09137045 |
| 42 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.02015592 |
| 43 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.00075120 |
| 44 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.99939571 |
| 45 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.91524325 |
| 46 | Alzheimers disease_Homo sapiens_hsa05010 | 0.87795398 |
| 47 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.84354125 |
| 48 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.83098289 |
| 49 | Carbon metabolism_Homo sapiens_hsa01200 | 0.79056564 |
| 50 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.78674225 |
| 51 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.77175761 |
| 52 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.75019767 |
| 53 | Phototransduction_Homo sapiens_hsa04744 | 0.72605574 |
| 54 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.71182877 |
| 55 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.63787954 |
| 56 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.63377567 |
| 57 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.56043321 |
| 58 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.53946329 |
| 59 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.53379450 |
| 60 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.50699214 |
| 61 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.50411250 |
| 62 | Sulfur relay system_Homo sapiens_hsa04122 | 0.49694476 |
| 63 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.49089322 |
| 64 | Metabolic pathways_Homo sapiens_hsa01100 | 0.44204822 |
| 65 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.42832792 |
| 66 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.42423937 |
| 67 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.42271774 |
| 68 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.39673136 |
| 69 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.39490767 |
| 70 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.37193510 |
| 71 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.37035995 |
| 72 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.35652167 |
| 73 | Peroxisome_Homo sapiens_hsa04146 | 0.35150543 |
| 74 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.32927023 |
| 75 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.31884718 |
| 76 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.30622128 |
| 77 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.29518792 |
| 78 | Thyroid cancer_Homo sapiens_hsa05216 | 0.29299600 |
| 79 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.28721202 |
| 80 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.28525666 |
| 81 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.27753286 |
| 82 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.27303477 |
| 83 | Galactose metabolism_Homo sapiens_hsa00052 | 0.27007199 |
| 84 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.22380492 |
| 85 | Tight junction_Homo sapiens_hsa04530 | 0.20985916 |
| 86 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.20729700 |
| 87 | Colorectal cancer_Homo sapiens_hsa05210 | 0.20575789 |
| 88 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.19902417 |
| 89 | HTLV-I infection_Homo sapiens_hsa05166 | 0.17713129 |
| 90 | Legionellosis_Homo sapiens_hsa05134 | 0.16943372 |
| 91 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.16293615 |
| 92 | Adherens junction_Homo sapiens_hsa04520 | 0.15486294 |
| 93 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.13970771 |
| 94 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.11369155 |
| 95 | Lysine degradation_Homo sapiens_hsa00310 | 0.10632067 |
| 96 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.07131449 |
| 97 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.07013963 |
| 98 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.05793680 |
| 99 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.04267541 |
| 100 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.03852909 |

