

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | translational termination (GO:0006415) | 6.25015392 |
| 2 | viral transcription (GO:0019083) | 6.19758578 |
| 3 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.86124831 |
| 4 | ATP synthesis coupled proton transport (GO:0015986) | 5.72766811 |
| 5 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.72766811 |
| 6 | ribosomal small subunit assembly (GO:0000028) | 5.68201640 |
| 7 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.60922485 |
| 8 | ribosomal large subunit biogenesis (GO:0042273) | 5.40251632 |
| 9 | regulation of mitochondrial translation (GO:0070129) | 5.39477704 |
| 10 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 5.25917204 |
| 11 | cotranslational protein targeting to membrane (GO:0006613) | 5.20264864 |
| 12 | establishment of integrated proviral latency (GO:0075713) | 5.19610073 |
| 13 | protein targeting to ER (GO:0045047) | 5.15244385 |
| 14 | translational elongation (GO:0006414) | 5.12457803 |
| 15 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 4.95551867 |
| 16 | chromatin remodeling at centromere (GO:0031055) | 4.93088752 |
| 17 | cellular protein complex disassembly (GO:0043624) | 4.89154540 |
| 18 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 4.83878881 |
| 19 | translational initiation (GO:0006413) | 4.82011710 |
| 20 | protein localization to endoplasmic reticulum (GO:0070972) | 4.81505545 |
| 21 | primitive streak formation (GO:0090009) | 4.71345537 |
| 22 | CENP-A containing nucleosome assembly (GO:0034080) | 4.62387737 |
| 23 | viral life cycle (GO:0019058) | 4.55764346 |
| 24 | DNA damage response, detection of DNA damage (GO:0042769) | 4.33081380 |
| 25 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.28086784 |
| 26 | protein complex disassembly (GO:0043241) | 4.25320072 |
| 27 | organelle disassembly (GO:1903008) | 4.22401734 |
| 28 | macromolecular complex disassembly (GO:0032984) | 4.19346973 |
| 29 | positive regulation of gastrulation (GO:2000543) | 4.12586856 |
| 30 | ribosomal small subunit biogenesis (GO:0042274) | 3.95662321 |
| 31 | peptidyl-histidine modification (GO:0018202) | 3.90494534 |
| 32 | respiratory electron transport chain (GO:0022904) | 3.86204793 |
| 33 | establishment of viral latency (GO:0019043) | 3.85290164 |
| 34 | proteasome assembly (GO:0043248) | 3.82616429 |
| 35 | histone exchange (GO:0043486) | 3.80688605 |
| 36 | translation (GO:0006412) | 3.76931050 |
| 37 | maturation of SSU-rRNA (GO:0030490) | 3.74070944 |
| 38 | electron transport chain (GO:0022900) | 3.70537323 |
| 39 | sequestering of actin monomers (GO:0042989) | 3.69862833 |
| 40 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.58551818 |
| 41 | DNA replication-independent nucleosome organization (GO:0034724) | 3.56347177 |
| 42 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.56347177 |
| 43 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 3.50296240 |
| 44 | regulation of translation, ncRNA-mediated (GO:0045974) | 3.50296240 |
| 45 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 3.50296240 |
| 46 | DNA ligation (GO:0006266) | 3.42221913 |
| 47 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.41535024 |
| 48 | ribonucleoprotein complex disassembly (GO:0032988) | 3.41099377 |
| 49 | generation of neurons (GO:0048699) | 3.40648661 |
| 50 | mRNA catabolic process (GO:0006402) | 3.39036974 |
| 51 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.36640949 |
| 52 | regulation of posttranscriptional gene silencing (GO:0060147) | 3.34517891 |
| 53 | regulation of gene silencing by miRNA (GO:0060964) | 3.34517891 |
| 54 | regulation of gene silencing by RNA (GO:0060966) | 3.34517891 |
| 55 | chaperone-mediated protein transport (GO:0072321) | 3.31489429 |
| 56 | protein targeting to membrane (GO:0006612) | 3.30382542 |
| 57 | spliceosomal snRNP assembly (GO:0000387) | 3.28448342 |
| 58 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.27136971 |
| 59 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.27136971 |
| 60 | somite rostral/caudal axis specification (GO:0032525) | 3.23923994 |
| 61 | RNA catabolic process (GO:0006401) | 3.19872542 |
| 62 | regulation of sulfur metabolic process (GO:0042762) | 3.19713720 |
| 63 | spliceosomal complex assembly (GO:0000245) | 3.18843071 |
| 64 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.15733927 |
| 65 | microtubule depolymerization (GO:0007019) | 3.12046235 |
| 66 | inner mitochondrial membrane organization (GO:0007007) | 3.11057700 |
| 67 | termination of RNA polymerase I transcription (GO:0006363) | 3.08215666 |
| 68 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.03927147 |
| 69 | ATP biosynthetic process (GO:0006754) | 3.02162776 |
| 70 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.01701123 |
| 71 | protein neddylation (GO:0045116) | 3.00806253 |
| 72 | genitalia morphogenesis (GO:0035112) | 3.00528798 |
| 73 | GMP metabolic process (GO:0046037) | 3.00077355 |
| 74 | cellular component biogenesis (GO:0044085) | 2.97596220 |
| 75 | IMP biosynthetic process (GO:0006188) | 2.96701755 |
| 76 | mitochondrial respiratory chain complex assembly (GO:0033108) | 2.96116740 |
| 77 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.91678541 |
| 78 | NADH dehydrogenase complex assembly (GO:0010257) | 2.91678541 |
| 79 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.91678541 |
| 80 | ATP-dependent chromatin remodeling (GO:0043044) | 2.85706130 |
| 81 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.85038850 |
| 82 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.84922630 |
| 83 | heterochromatin organization (GO:0070828) | 2.82511957 |
| 84 | protein complex biogenesis (GO:0070271) | 2.82324687 |
| 85 | histone mRNA metabolic process (GO:0008334) | 2.80553068 |
| 86 | regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510) | 2.79395473 |
| 87 | mRNA splice site selection (GO:0006376) | 2.79321365 |
| 88 | termination of RNA polymerase II transcription (GO:0006369) | 2.79153199 |
| 89 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 2.77557853 |
| 90 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 2.77523994 |
| 91 | regulation of helicase activity (GO:0051095) | 2.76803962 |
| 92 | DNA-templated transcription, termination (GO:0006353) | 2.76691351 |
| 93 | protein localization to cilium (GO:0061512) | 2.72568506 |
| 94 | single strand break repair (GO:0000012) | 2.71395746 |
| 95 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.69561930 |
| 96 | female gonad development (GO:0008585) | 2.69009806 |
| 97 | regulation of coenzyme metabolic process (GO:0051196) | 2.68069164 |
| 98 | regulation of cofactor metabolic process (GO:0051193) | 2.68069164 |
| 99 | rRNA processing (GO:0006364) | 2.67527045 |
| 100 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.66529695 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.03496793 |
| 2 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.03064973 |
| 3 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.98538960 |
| 4 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.92850201 |
| 5 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 3.51095735 |
| 6 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.36488151 |
| 7 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.35237584 |
| 8 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.04335913 |
| 9 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.89902408 |
| 10 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.87782430 |
| 11 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 2.84196245 |
| 12 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.83923234 |
| 13 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.82778363 |
| 14 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.67892073 |
| 15 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.58823882 |
| 16 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.54778080 |
| 17 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.54341815 |
| 18 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.45377589 |
| 19 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.41255586 |
| 20 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.29021654 |
| 21 | EWS_26573619_Chip-Seq_HEK293_Human | 2.24241494 |
| 22 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.11043202 |
| 23 | FUS_26573619_Chip-Seq_HEK293_Human | 2.06349364 |
| 24 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.99605356 |
| 25 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.98907408 |
| 26 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.95127771 |
| 27 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.94235390 |
| 28 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.88658329 |
| 29 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.83858327 |
| 30 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.80789578 |
| 31 | VDR_22108803_ChIP-Seq_LS180_Human | 1.79674255 |
| 32 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.78270930 |
| 33 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.73452053 |
| 34 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.72675933 |
| 35 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.69705019 |
| 36 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.68486319 |
| 37 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.68441976 |
| 38 | P300_19829295_ChIP-Seq_ESCs_Human | 1.61557064 |
| 39 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.59130380 |
| 40 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.56182551 |
| 41 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.52944691 |
| 42 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.51759036 |
| 43 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.50311112 |
| 44 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.50093179 |
| 45 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.49659893 |
| 46 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.47342360 |
| 47 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.44853020 |
| 48 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.41703043 |
| 49 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.40412534 |
| 50 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.40272488 |
| 51 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.39465261 |
| 52 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.38205119 |
| 53 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.37393490 |
| 54 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.33244829 |
| 55 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.32690607 |
| 56 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.31011415 |
| 57 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.30029925 |
| 58 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.28669354 |
| 59 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.26718173 |
| 60 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.26694346 |
| 61 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.22231997 |
| 62 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.20804866 |
| 63 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.20605749 |
| 64 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.15980469 |
| 65 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.14613824 |
| 66 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.11438188 |
| 67 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.09768499 |
| 68 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.08840783 |
| 69 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.07994464 |
| 70 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.07700834 |
| 71 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.07141922 |
| 72 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.06726921 |
| 73 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.01289827 |
| 74 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.01168629 |
| 75 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.00600236 |
| 76 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.99478205 |
| 77 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.98321632 |
| 78 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.98321632 |
| 79 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.98062145 |
| 80 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.98062145 |
| 81 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.97502232 |
| 82 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.97441996 |
| 83 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 0.95353455 |
| 84 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.92825894 |
| 85 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 0.92446670 |
| 86 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 0.92380330 |
| 87 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.91241685 |
| 88 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.90085903 |
| 89 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.90030327 |
| 90 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.89980392 |
| 91 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 0.89969569 |
| 92 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.89895664 |
| 93 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.86410211 |
| 94 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.85664184 |
| 95 | LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.85188935 |
| 96 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.84895092 |
| 97 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.83778526 |
| 98 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.83609352 |
| 99 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 0.83286759 |
| 100 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.80973346 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0009379_abnormal_foot_pigmentation | 4.66024091 |
| 2 | MP0003890_abnormal_embryonic-extraembry | 4.14570407 |
| 3 | MP0003315_abnormal_perineum_morphology | 3.12325386 |
| 4 | MP0001529_abnormal_vocalization | 3.05821549 |
| 5 | MP0002277_abnormal_respiratory_mucosa | 2.82529303 |
| 6 | MP0005187_abnormal_penis_morphology | 2.80924058 |
| 7 | MP0003136_yellow_coat_color | 2.77938877 |
| 8 | MP0001188_hyperpigmentation | 2.51852467 |
| 9 | MP0005377_hearing/vestibular/ear_phenot | 2.39159890 |
| 10 | MP0003878_abnormal_ear_physiology | 2.39159890 |
| 11 | MP0004957_abnormal_blastocyst_morpholog | 2.30666633 |
| 12 | MP0006292_abnormal_olfactory_placode | 2.28070808 |
| 13 | MP0002938_white_spotting | 2.22300091 |
| 14 | MP0003119_abnormal_digestive_system | 2.17277485 |
| 15 | MP0008058_abnormal_DNA_repair | 2.09424472 |
| 16 | MP0010094_abnormal_chromosome_stability | 2.08161715 |
| 17 | MP0008995_early_reproductive_senescence | 2.07207897 |
| 18 | MP0000372_irregular_coat_pigmentation | 2.00243254 |
| 19 | MP0003941_abnormal_skin_development | 1.99626157 |
| 20 | MP0004133_heterotaxia | 1.90146077 |
| 21 | MP0003186_abnormal_redox_activity | 1.89792458 |
| 22 | MP0002736_abnormal_nociception_after | 1.82659370 |
| 23 | MP0003880_abnormal_central_pattern | 1.78985580 |
| 24 | MP0001293_anophthalmia | 1.76442246 |
| 25 | MP0009697_abnormal_copulation | 1.72811047 |
| 26 | MP0002697_abnormal_eye_size | 1.71956868 |
| 27 | MP0000569_abnormal_digit_pigmentation | 1.70611845 |
| 28 | MP0003718_maternal_effect | 1.66384763 |
| 29 | MP0002751_abnormal_autonomic_nervous | 1.65696502 |
| 30 | MP0001286_abnormal_eye_development | 1.64720843 |
| 31 | MP0002928_abnormal_bile_duct | 1.50505905 |
| 32 | MP0000647_abnormal_sebaceous_gland | 1.48710417 |
| 33 | MP0003567_abnormal_fetal_cardiomyocyte | 1.48537918 |
| 34 | MP0001919_abnormal_reproductive_system | 1.48371508 |
| 35 | MP0003077_abnormal_cell_cycle | 1.45264055 |
| 36 | MP0001879_abnormal_lymphatic_vessel | 1.45007993 |
| 37 | MP0006276_abnormal_autonomic_nervous | 1.44629919 |
| 38 | MP0003121_genomic_imprinting | 1.44392054 |
| 39 | MP0003123_paternal_imprinting | 1.42614813 |
| 40 | MP0008932_abnormal_embryonic_tissue | 1.40778885 |
| 41 | MP0000631_abnormal_neuroendocrine_gland | 1.36150998 |
| 42 | MP0002210_abnormal_sex_determination | 1.33492269 |
| 43 | MP0000778_abnormal_nervous_system | 1.30582038 |
| 44 | MP0008789_abnormal_olfactory_epithelium | 1.26340602 |
| 45 | MP0002163_abnormal_gland_morphology | 1.25096221 |
| 46 | MP0006035_abnormal_mitochondrial_morpho | 1.23023449 |
| 47 | MP0002837_dystrophic_cardiac_calcinosis | 1.21971095 |
| 48 | MP0005084_abnormal_gallbladder_morpholo | 1.16753905 |
| 49 | MP0006072_abnormal_retinal_apoptosis | 1.16366562 |
| 50 | MP0001968_abnormal_touch/_nociception | 1.14986870 |
| 51 | MP0001984_abnormal_olfaction | 1.14826464 |
| 52 | MP0002234_abnormal_pharynx_morphology | 1.13734260 |
| 53 | MP0006054_spinal_hemorrhage | 1.12680969 |
| 54 | MP0005394_taste/olfaction_phenotype | 1.10277528 |
| 55 | MP0005499_abnormal_olfactory_system | 1.10277528 |
| 56 | MP0001485_abnormal_pinna_reflex | 1.08922741 |
| 57 | MP0003937_abnormal_limbs/digits/tail_de | 1.06004156 |
| 58 | MP0003938_abnormal_ear_development | 1.03048006 |
| 59 | MP0003111_abnormal_nucleus_morphology | 0.98201452 |
| 60 | MP0001324_abnormal_eye_pigmentation | 0.97824765 |
| 61 | MP0003221_abnormal_cardiomyocyte_apopto | 0.97133107 |
| 62 | MP0005389_reproductive_system_phenotype | 0.96938885 |
| 63 | MP0001929_abnormal_gametogenesis | 0.95727056 |
| 64 | MP0002085_abnormal_embryonic_tissue | 0.94559270 |
| 65 | MP0008057_abnormal_DNA_replication | 0.94437898 |
| 66 | MP0003693_abnormal_embryo_hatching | 0.91143352 |
| 67 | MP0002734_abnormal_mechanical_nocicepti | 0.90734208 |
| 68 | MP0005075_abnormal_melanosome_morpholog | 0.88980068 |
| 69 | MP0004742_abnormal_vestibular_system | 0.85540195 |
| 70 | MP0000653_abnormal_sex_gland | 0.85443631 |
| 71 | MP0002233_abnormal_nose_morphology | 0.84828860 |
| 72 | MP0003806_abnormal_nucleotide_metabolis | 0.84145325 |
| 73 | MP0001672_abnormal_embryogenesis/_devel | 0.84122317 |
| 74 | MP0005380_embryogenesis_phenotype | 0.84122317 |
| 75 | MP0001346_abnormal_lacrimal_gland | 0.83567795 |
| 76 | MP0000049_abnormal_middle_ear | 0.83129721 |
| 77 | MP0003861_abnormal_nervous_system | 0.81535138 |
| 78 | MP0002089_abnormal_postnatal_growth/wei | 0.81409804 |
| 79 | MP0008961_abnormal_basal_metabolism | 0.80515812 |
| 80 | MP0002090_abnormal_vision | 0.80273360 |
| 81 | MP0003195_calcinosis | 0.80187978 |
| 82 | MP0005195_abnormal_posterior_eye | 0.80017858 |
| 83 | MP0002084_abnormal_developmental_patter | 0.79387897 |
| 84 | MP0002557_abnormal_social/conspecific_i | 0.78412038 |
| 85 | MP0003698_abnormal_male_reproductive | 0.78296609 |
| 86 | MP0000955_abnormal_spinal_cord | 0.77245466 |
| 87 | MP0003122_maternal_imprinting | 0.77181993 |
| 88 | MP0005167_abnormal_blood-brain_barrier | 0.76909254 |
| 89 | MP0005379_endocrine/exocrine_gland_phen | 0.76882127 |
| 90 | MP0005551_abnormal_eye_electrophysiolog | 0.76326109 |
| 91 | MP0005408_hypopigmentation | 0.76245014 |
| 92 | MP0002735_abnormal_chemical_nociception | 0.75180382 |
| 93 | MP0002088_abnormal_embryonic_growth/wei | 0.74098957 |
| 94 | MP0001145_abnormal_male_reproductive | 0.72897459 |
| 95 | MP0003984_embryonic_growth_retardation | 0.72736463 |
| 96 | MP0002161_abnormal_fertility/fecundity | 0.71909160 |
| 97 | MP0000350_abnormal_cell_proliferation | 0.70047755 |
| 98 | MP0009672_abnormal_birth_weight | 0.69888682 |
| 99 | MP0004270_analgesia | 0.69681242 |
| 100 | MP0001119_abnormal_female_reproductive | 0.69369049 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Reticulocytopenia (HP:0001896) | 4.45210809 |
| 2 | Acute necrotizing encephalopathy (HP:0006965) | 4.07342394 |
| 3 | Absent septum pellucidum (HP:0001331) | 3.91962453 |
| 4 | Septo-optic dysplasia (HP:0100842) | 3.87602884 |
| 5 | Abnormal number of erythroid precursors (HP:0012131) | 3.71861506 |
| 6 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.70375128 |
| 7 | Abnormality of the septum pellucidum (HP:0007375) | 3.62124690 |
| 8 | Increased hepatocellular lipid droplets (HP:0006565) | 3.58336854 |
| 9 | Macrocytic anemia (HP:0001972) | 3.51885470 |
| 10 | Mitochondrial inheritance (HP:0001427) | 3.44237037 |
| 11 | Progressive macrocephaly (HP:0004481) | 3.43137714 |
| 12 | Lipid accumulation in hepatocytes (HP:0006561) | 3.41266443 |
| 13 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.36679273 |
| 14 | Acute encephalopathy (HP:0006846) | 3.28221109 |
| 15 | Hepatic necrosis (HP:0002605) | 3.17900725 |
| 16 | Colon cancer (HP:0003003) | 3.15584768 |
| 17 | Increased CSF lactate (HP:0002490) | 3.15565738 |
| 18 | Hepatocellular necrosis (HP:0001404) | 3.10244436 |
| 19 | Congenital, generalized hypertrichosis (HP:0004540) | 3.01861467 |
| 20 | Pancreatic cysts (HP:0001737) | 2.94701202 |
| 21 | Renal Fanconi syndrome (HP:0001994) | 2.83432390 |
| 22 | Hyperglycinemia (HP:0002154) | 2.74083297 |
| 23 | Limb dystonia (HP:0002451) | 2.72993560 |
| 24 | Cerebral edema (HP:0002181) | 2.66289589 |
| 25 | Maternal diabetes (HP:0009800) | 2.64376733 |
| 26 | Optic disc pallor (HP:0000543) | 2.61532206 |
| 27 | Hypoplastic left heart (HP:0004383) | 2.61282488 |
| 28 | Supernumerary spleens (HP:0009799) | 2.60894563 |
| 29 | Bilateral microphthalmos (HP:0007633) | 2.60300781 |
| 30 | Pallor (HP:0000980) | 2.59431961 |
| 31 | Pendular nystagmus (HP:0012043) | 2.57547675 |
| 32 | Confusion (HP:0001289) | 2.54609240 |
| 33 | Abnormality of renal resorption (HP:0011038) | 2.51895866 |
| 34 | Hyperglycinuria (HP:0003108) | 2.40063192 |
| 35 | Generalized aminoaciduria (HP:0002909) | 2.39699311 |
| 36 | Abnormality of the labia minora (HP:0012880) | 2.36176983 |
| 37 | Attenuation of retinal blood vessels (HP:0007843) | 2.31893560 |
| 38 | Carpal bone hypoplasia (HP:0001498) | 2.30662118 |
| 39 | Abnormal lung lobation (HP:0002101) | 2.30302217 |
| 40 | True hermaphroditism (HP:0010459) | 2.28923076 |
| 41 | Hypoplasia of the pons (HP:0012110) | 2.22918683 |
| 42 | Amniotic constriction ring (HP:0009775) | 2.21721844 |
| 43 | Abnormality of placental membranes (HP:0011409) | 2.21721844 |
| 44 | Abnormality of the pons (HP:0007361) | 2.20397913 |
| 45 | Leukodystrophy (HP:0002415) | 2.18359553 |
| 46 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.18083323 |
| 47 | Meckel diverticulum (HP:0002245) | 2.17551251 |
| 48 | Pancreatic fibrosis (HP:0100732) | 2.13012701 |
| 49 | Hypoplastic heart (HP:0001961) | 2.11648940 |
| 50 | Woolly hair (HP:0002224) | 2.11498027 |
| 51 | Anencephaly (HP:0002323) | 2.10805926 |
| 52 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.09484059 |
| 53 | Cortical dysplasia (HP:0002539) | 2.08444272 |
| 54 | Hypothermia (HP:0002045) | 2.05923930 |
| 55 | Myelomeningocele (HP:0002475) | 2.05290587 |
| 56 | Exertional dyspnea (HP:0002875) | 2.03836936 |
| 57 | Absent eyebrow (HP:0002223) | 2.03216174 |
| 58 | Anophthalmia (HP:0000528) | 2.02896122 |
| 59 | Optic nerve hypoplasia (HP:0000609) | 2.00317063 |
| 60 | Rectal fistula (HP:0100590) | 1.98608826 |
| 61 | Rectovaginal fistula (HP:0000143) | 1.98608826 |
| 62 | Abnormality of the ileum (HP:0001549) | 1.97726011 |
| 63 | Abnormality of methionine metabolism (HP:0010901) | 1.97212790 |
| 64 | Triphalangeal thumb (HP:0001199) | 1.92237493 |
| 65 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.92134255 |
| 66 | Febrile seizures (HP:0002373) | 1.91659558 |
| 67 | Flat occiput (HP:0005469) | 1.89846508 |
| 68 | Volvulus (HP:0002580) | 1.88089805 |
| 69 | Respiratory difficulties (HP:0002880) | 1.86677720 |
| 70 | Glycosuria (HP:0003076) | 1.84092587 |
| 71 | Abnormality of urine glucose concentration (HP:0011016) | 1.84092587 |
| 72 | Abnormality of serum amino acid levels (HP:0003112) | 1.82706302 |
| 73 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.82491149 |
| 74 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.80767040 |
| 75 | Molar tooth sign on MRI (HP:0002419) | 1.79243818 |
| 76 | Abnormality of midbrain morphology (HP:0002418) | 1.79243818 |
| 77 | Hypogonadotrophic hypogonadism (HP:0000044) | 1.79048434 |
| 78 | Parakeratosis (HP:0001036) | 1.78559118 |
| 79 | Aplastic anemia (HP:0001915) | 1.77661421 |
| 80 | Increased serum lactate (HP:0002151) | 1.77071565 |
| 81 | Abnormal hair whorl (HP:0010721) | 1.75856709 |
| 82 | Absent hair (HP:0002298) | 1.75305628 |
| 83 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 1.74756850 |
| 84 | Nephronophthisis (HP:0000090) | 1.72862979 |
| 85 | Dysphonia (HP:0001618) | 1.72757697 |
| 86 | Exercise intolerance (HP:0003546) | 1.70273067 |
| 87 | Hypoglycemic coma (HP:0001325) | 1.70217321 |
| 88 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.69868126 |
| 89 | Dandy-Walker malformation (HP:0001305) | 1.69631672 |
| 90 | Polyuria (HP:0000103) | 1.69412084 |
| 91 | Oligodactyly (hands) (HP:0001180) | 1.68540779 |
| 92 | Proximal tubulopathy (HP:0000114) | 1.67465857 |
| 93 | Sparse eyelashes (HP:0000653) | 1.66911150 |
| 94 | Abnormality of chromosome stability (HP:0003220) | 1.66553169 |
| 95 | X-linked dominant inheritance (HP:0001423) | 1.66518087 |
| 96 | Lactic acidosis (HP:0003128) | 1.65073893 |
| 97 | Restlessness (HP:0000711) | 1.64906136 |
| 98 | Atrioventricular canal defect (HP:0006695) | 1.64581223 |
| 99 | Reduced antithrombin III activity (HP:0001976) | 1.63265839 |
| 100 | Cellular immunodeficiency (HP:0005374) | 1.63037982 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TNIK | 8.12664237 |
| 2 | VRK2 | 4.91656894 |
| 3 | TRIM28 | 2.90001140 |
| 4 | NLK | 2.71282172 |
| 5 | MARK1 | 2.45555485 |
| 6 | DYRK3 | 2.45126180 |
| 7 | CDC7 | 2.41764372 |
| 8 | BUB1 | 2.35163212 |
| 9 | PASK | 2.22179607 |
| 10 | EIF2AK3 | 2.13475409 |
| 11 | TSSK6 | 2.10316031 |
| 12 | SRPK1 | 2.07723161 |
| 13 | AKT3 | 2.02719293 |
| 14 | TAF1 | 1.91271341 |
| 15 | VRK1 | 1.91125129 |
| 16 | MUSK | 1.81925779 |
| 17 | MKNK2 | 1.78199314 |
| 18 | MAP3K10 | 1.67348364 |
| 19 | ZAK | 1.66044123 |
| 20 | EIF2AK1 | 1.62743204 |
| 21 | MKNK1 | 1.57260810 |
| 22 | NME1 | 1.44242284 |
| 23 | PNCK | 1.43752620 |
| 24 | PLK4 | 1.39595374 |
| 25 | NEK1 | 1.39524031 |
| 26 | TTK | 1.37504683 |
| 27 | DYRK2 | 1.32496181 |
| 28 | PLK3 | 1.28780038 |
| 29 | PBK | 1.25208568 |
| 30 | BRAF | 1.11055773 |
| 31 | GRK7 | 1.08144029 |
| 32 | TLK1 | 1.07044385 |
| 33 | FLT3 | 1.06197048 |
| 34 | MST4 | 1.06100412 |
| 35 | ACVR1B | 0.97517904 |
| 36 | STK16 | 0.97207475 |
| 37 | RPS6KA4 | 0.96025717 |
| 38 | WNK3 | 0.95651384 |
| 39 | FGFR1 | 0.89079886 |
| 40 | PKN2 | 0.88031349 |
| 41 | DMPK | 0.86738131 |
| 42 | NEK2 | 0.81756033 |
| 43 | MAP3K4 | 0.79484109 |
| 44 | NME2 | 0.75473797 |
| 45 | NTRK2 | 0.75322159 |
| 46 | CSNK1G2 | 0.71786341 |
| 47 | KDR | 0.69782797 |
| 48 | ALK | 0.68498627 |
| 49 | OXSR1 | 0.68464220 |
| 50 | CASK | 0.66801605 |
| 51 | BCKDK | 0.65080492 |
| 52 | EPHB2 | 0.64885314 |
| 53 | PDK2 | 0.61573788 |
| 54 | NTRK1 | 0.61068624 |
| 55 | DYRK1A | 0.60948090 |
| 56 | MAP2K7 | 0.58110402 |
| 57 | AURKB | 0.56746060 |
| 58 | CSNK2A2 | 0.56689716 |
| 59 | CDK8 | 0.56006672 |
| 60 | TGFBR1 | 0.55127928 |
| 61 | CSNK1G1 | 0.54960061 |
| 62 | GRK1 | 0.54887708 |
| 63 | WEE1 | 0.54787597 |
| 64 | SGK2 | 0.53866848 |
| 65 | CHUK | 0.53628517 |
| 66 | NUAK1 | 0.53519700 |
| 67 | CSNK2A1 | 0.52284540 |
| 68 | CSNK1G3 | 0.48326553 |
| 69 | ADRBK2 | 0.48093946 |
| 70 | BCR | 0.47880862 |
| 71 | RPS6KA5 | 0.47095309 |
| 72 | PRKCG | 0.45763117 |
| 73 | STK39 | 0.44914181 |
| 74 | CSNK1E | 0.44160772 |
| 75 | PLK1 | 0.42939888 |
| 76 | CSNK1A1L | 0.41296946 |
| 77 | CHEK2 | 0.41288188 |
| 78 | NTRK3 | 0.41118834 |
| 79 | PINK1 | 0.39822113 |
| 80 | CDK3 | 0.39458980 |
| 81 | TYRO3 | 0.37336303 |
| 82 | TYK2 | 0.36726023 |
| 83 | PLK2 | 0.36421120 |
| 84 | CSNK1A1 | 0.35615886 |
| 85 | DYRK1B | 0.32885003 |
| 86 | ATR | 0.30966040 |
| 87 | IKBKE | 0.30959369 |
| 88 | PRKG1 | 0.30541875 |
| 89 | WNK4 | 0.26345706 |
| 90 | KIT | 0.25881047 |
| 91 | MINK1 | 0.25158875 |
| 92 | ATM | 0.23543636 |
| 93 | PRKCB | 0.22847215 |
| 94 | MAPK15 | 0.22688109 |
| 95 | MAP2K6 | 0.22404429 |
| 96 | PTK6 | 0.21769845 |
| 97 | ADRBK1 | 0.21571857 |
| 98 | STK4 | 0.20296540 |
| 99 | MATK | 0.20295684 |
| 100 | CHEK1 | 0.19660400 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 5.81206843 |
| 2 | Proteasome_Homo sapiens_hsa03050 | 4.27446570 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.14814247 |
| 4 | Parkinsons disease_Homo sapiens_hsa05012 | 3.44411456 |
| 5 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.95543959 |
| 6 | Huntingtons disease_Homo sapiens_hsa05016 | 2.73556995 |
| 7 | RNA polymerase_Homo sapiens_hsa03020 | 2.69591699 |
| 8 | Mismatch repair_Homo sapiens_hsa03430 | 2.48001299 |
| 9 | Spliceosome_Homo sapiens_hsa03040 | 2.45745395 |
| 10 | Alzheimers disease_Homo sapiens_hsa05010 | 2.41193949 |
| 11 | Protein export_Homo sapiens_hsa03060 | 2.25548564 |
| 12 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.06250424 |
| 13 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.04448307 |
| 14 | Homologous recombination_Homo sapiens_hsa03440 | 1.95639312 |
| 15 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.94698804 |
| 16 | RNA transport_Homo sapiens_hsa03013 | 1.93456432 |
| 17 | DNA replication_Homo sapiens_hsa03030 | 1.90418408 |
| 18 | RNA degradation_Homo sapiens_hsa03018 | 1.85884661 |
| 19 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.83083357 |
| 20 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.82011146 |
| 21 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.74678966 |
| 22 | Basal transcription factors_Homo sapiens_hsa03022 | 1.70907902 |
| 23 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.57365800 |
| 24 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.44375851 |
| 25 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.42583580 |
| 26 | Base excision repair_Homo sapiens_hsa03410 | 1.42133257 |
| 27 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.33355907 |
| 28 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.29924358 |
| 29 | Thyroid cancer_Homo sapiens_hsa05216 | 1.24690222 |
| 30 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.22990496 |
| 31 | Purine metabolism_Homo sapiens_hsa00230 | 1.19176136 |
| 32 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.18301327 |
| 33 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.17146104 |
| 34 | Phototransduction_Homo sapiens_hsa04744 | 1.13376185 |
| 35 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.13115604 |
| 36 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.10633774 |
| 37 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.07991321 |
| 38 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.07671046 |
| 39 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.03974141 |
| 40 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.01393553 |
| 41 | Cell cycle_Homo sapiens_hsa04110 | 1.01253265 |
| 42 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.00134389 |
| 43 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.96767600 |
| 44 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.89029144 |
| 45 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.81749565 |
| 46 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.81370199 |
| 47 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.74572676 |
| 48 | Nicotine addiction_Homo sapiens_hsa05033 | 0.71728765 |
| 49 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.66868246 |
| 50 | Mineral absorption_Homo sapiens_hsa04978 | 0.66720160 |
| 51 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.61187749 |
| 52 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.60327925 |
| 53 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.57487950 |
| 54 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.56469056 |
| 55 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.56186642 |
| 56 | Metabolic pathways_Homo sapiens_hsa01100 | 0.55586965 |
| 57 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.54349488 |
| 58 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.53169805 |
| 59 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.52295969 |
| 60 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.50036408 |
| 61 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.48629504 |
| 62 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.45933739 |
| 63 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.42047471 |
| 64 | Olfactory transduction_Homo sapiens_hsa04740 | 0.41898638 |
| 65 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.41347208 |
| 66 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.41172467 |
| 67 | Taste transduction_Homo sapiens_hsa04742 | 0.40943255 |
| 68 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.38245912 |
| 69 | Carbon metabolism_Homo sapiens_hsa01200 | 0.37773526 |
| 70 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.37613347 |
| 71 | Colorectal cancer_Homo sapiens_hsa05210 | 0.35893821 |
| 72 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.34692200 |
| 73 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.34232363 |
| 74 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.33852714 |
| 75 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.32438944 |
| 76 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.32284839 |
| 77 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.31327801 |
| 78 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.30989391 |
| 79 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.30578328 |
| 80 | Adherens junction_Homo sapiens_hsa04520 | 0.29121733 |
| 81 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.28327131 |
| 82 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.26747245 |
| 83 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.25087923 |
| 84 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.24707550 |
| 85 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.21749138 |
| 86 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.18986618 |
| 87 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.18517724 |
| 88 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.18202242 |
| 89 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.17843340 |
| 90 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.17387252 |
| 91 | Retinol metabolism_Homo sapiens_hsa00830 | 0.13209291 |
| 92 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.12948284 |
| 93 | Histidine metabolism_Homo sapiens_hsa00340 | 0.11270906 |
| 94 | Prostate cancer_Homo sapiens_hsa05215 | 0.10941893 |
| 95 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.10485840 |
| 96 | Alcoholism_Homo sapiens_hsa05034 | 0.10015865 |
| 97 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.09087927 |
| 98 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.07208623 |
| 99 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.06517482 |
| 100 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.06293275 |

