Rank | Gene Set | Z-score |
---|---|---|
1 | DNA unwinding involved in DNA replication (GO:0006268) | 5.40978359 |
2 | negative regulation of erythrocyte differentiation (GO:0045647) | 4.73609676 |
3 | protein localization to kinetochore (GO:0034501) | 4.51101386 |
4 | nuclear pore organization (GO:0006999) | 4.23066845 |
5 | 3-UTR-mediated mRNA stabilization (GO:0070935) | 4.21784275 |
6 | mitotic nuclear envelope disassembly (GO:0007077) | 4.10396483 |
7 | pre-miRNA processing (GO:0031054) | 4.09496166 |
8 | DNA replication initiation (GO:0006270) | 4.09441392 |
9 | nuclear pore complex assembly (GO:0051292) | 4.08788227 |
10 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.08098832 |
11 | mitotic sister chromatid segregation (GO:0000070) | 4.02641350 |
12 | regulation of RNA export from nucleus (GO:0046831) | 3.97850695 |
13 | negative regulation of mRNA splicing, via spliceosome (GO:0048025) | 3.93813491 |
14 | sister chromatid segregation (GO:0000819) | 3.92802276 |
15 | DNA strand elongation (GO:0022616) | 3.84348077 |
16 | membrane disassembly (GO:0030397) | 3.82855193 |
17 | nuclear envelope disassembly (GO:0051081) | 3.82855193 |
18 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.75620736 |
19 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.75620736 |
20 | protein localization to chromosome, centromeric region (GO:0071459) | 3.74514477 |
21 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.71955182 |
22 | mitotic metaphase plate congression (GO:0007080) | 3.68834981 |
23 | DNA duplex unwinding (GO:0032508) | 3.66319019 |
24 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.63935422 |
25 | negative regulation of RNA splicing (GO:0033119) | 3.63113940 |
26 | DNA geometric change (GO:0032392) | 3.63051832 |
27 | regulation of nucleobase-containing compound transport (GO:0032239) | 3.60336025 |
28 | RNA stabilization (GO:0043489) | 3.58529094 |
29 | mRNA stabilization (GO:0048255) | 3.58529094 |
30 | regulation of histone H3-K27 methylation (GO:0061085) | 3.57069758 |
31 | formation of translation preinitiation complex (GO:0001731) | 3.55222401 |
32 | IMP biosynthetic process (GO:0006188) | 3.53344268 |
33 | heterochromatin organization (GO:0070828) | 3.47384984 |
34 | maturation of SSU-rRNA (GO:0030490) | 3.45969528 |
35 | mitotic chromosome condensation (GO:0007076) | 3.44647421 |
36 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.43575545 |
37 | negative regulation of histone methylation (GO:0031061) | 3.42187106 |
38 | regulation of chromatin binding (GO:0035561) | 3.40942195 |
39 | negative regulation of mRNA processing (GO:0050686) | 3.39561298 |
40 | regulation of NFAT protein import into nucleus (GO:0051532) | 3.39277513 |
41 | ribosomal small subunit biogenesis (GO:0042274) | 3.37220948 |
42 | peptidyl-arginine omega-N-methylation (GO:0035247) | 3.35992677 |
43 | regulation of posttranscriptional gene silencing (GO:0060147) | 3.35829502 |
44 | regulation of gene silencing by miRNA (GO:0060964) | 3.35829502 |
45 | regulation of gene silencing by RNA (GO:0060966) | 3.35829502 |
46 | mitotic recombination (GO:0006312) | 3.34015000 |
47 | DNA replication checkpoint (GO:0000076) | 3.33833335 |
48 | metaphase plate congression (GO:0051310) | 3.32648146 |
49 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.28599385 |
50 | regulation of spindle organization (GO:0090224) | 3.27317297 |
51 | telomere maintenance via recombination (GO:0000722) | 3.26117550 |
52 | regulation of translational fidelity (GO:0006450) | 3.22814185 |
53 | nucleobase biosynthetic process (GO:0046112) | 3.22708584 |
54 | thymic T cell selection (GO:0045061) | 3.21479795 |
55 | dosage compensation (GO:0007549) | 3.20173425 |
56 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.18730394 |
57 | positive regulation of chromosome segregation (GO:0051984) | 3.17877997 |
58 | mitotic sister chromatid cohesion (GO:0007064) | 3.17444098 |
59 | negative regulation of mRNA metabolic process (GO:1903312) | 3.17104889 |
60 | pore complex assembly (GO:0046931) | 3.16783417 |
61 | ribosomal small subunit assembly (GO:0000028) | 3.15953610 |
62 | telomere maintenance via telomere lengthening (GO:0010833) | 3.14857009 |
63 | spliceosomal tri-snRNP complex assembly (GO:0000244) | 3.12430497 |
64 | kinetochore organization (GO:0051383) | 3.12199728 |
65 | positive thymic T cell selection (GO:0045059) | 3.12176659 |
66 | * RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377) | 3.11877447 |
67 | * mRNA splicing, via spliceosome (GO:0000398) | 3.11877447 |
68 | * RNA splicing, via transesterification reactions (GO:0000375) | 3.11058689 |
69 | regulation of histone H3-K9 methylation (GO:0051570) | 3.09920162 |
70 | intracellular estrogen receptor signaling pathway (GO:0030520) | 3.09855426 |
71 | regulation of sister chromatid cohesion (GO:0007063) | 3.08693761 |
72 | viral transcription (GO:0019083) | 3.08224839 |
73 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.08063140 |
74 | negative regulation of chromosome segregation (GO:0051985) | 3.06081318 |
75 | regulation of mammary gland epithelial cell proliferation (GO:0033599) | 3.03821665 |
76 | translational termination (GO:0006415) | 3.03286484 |
77 | nuclear envelope organization (GO:0006998) | 3.01681505 |
78 | apoptotic process involved in morphogenesis (GO:0060561) | 3.01239645 |
79 | paraxial mesoderm development (GO:0048339) | 3.01071396 |
80 | translesion synthesis (GO:0019985) | 2.99449825 |
81 | regulation of chromosome segregation (GO:0051983) | 2.98314393 |
82 | IMP metabolic process (GO:0046040) | 2.98092247 |
83 | attachment of spindle microtubules to kinetochore (GO:0008608) | 2.97561127 |
84 | establishment of chromosome localization (GO:0051303) | 2.97239524 |
85 | spindle assembly checkpoint (GO:0071173) | 2.96884957 |
86 | DNA conformation change (GO:0071103) | 2.96658578 |
87 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 2.96472511 |
88 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 2.96472511 |
89 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 2.96472511 |
90 | negative regulation of sister chromatid segregation (GO:0033046) | 2.96472511 |
91 | mitotic spindle assembly checkpoint (GO:0007094) | 2.96241262 |
92 | DNA replication-independent nucleosome organization (GO:0034724) | 2.94789500 |
93 | DNA replication-independent nucleosome assembly (GO:0006336) | 2.94789500 |
94 | chromatin assembly or disassembly (GO:0006333) | 2.94718548 |
95 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 2.94424282 |
96 | peptidyl-arginine methylation (GO:0018216) | 2.94098451 |
97 | peptidyl-arginine N-methylation (GO:0035246) | 2.94098451 |
98 | histone arginine methylation (GO:0034969) | 2.93090911 |
99 | protein localization to chromosome (GO:0034502) | 2.92641958 |
100 | histone H3-K36 demethylation (GO:0070544) | 2.92471766 |
101 | cellular response to interleukin-4 (GO:0071353) | 2.92088691 |
102 | chromatin assembly (GO:0031497) | 2.91708216 |
103 | DNA topological change (GO:0006265) | 2.90091735 |
104 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.90088301 |
105 | translational initiation (GO:0006413) | 2.89972967 |
106 | ribosomal large subunit biogenesis (GO:0042273) | 2.89750638 |
107 | ribosome biogenesis (GO:0042254) | 2.89575816 |
108 | spliceosomal snRNP assembly (GO:0000387) | 2.88589288 |
109 | regulation of mitotic spindle organization (GO:0060236) | 2.88483355 |
110 | ribosome assembly (GO:0042255) | 2.88261298 |
111 | protein-DNA complex disassembly (GO:0032986) | 2.87785092 |
112 | nucleosome disassembly (GO:0006337) | 2.87785092 |
113 | alternative mRNA splicing, via spliceosome (GO:0000380) | 2.87537396 |
114 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 2.87389356 |
115 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 2.87385390 |
116 | spindle checkpoint (GO:0031577) | 2.87136781 |
117 | chromosome condensation (GO:0030261) | 2.87055663 |
118 | histone H4-K12 acetylation (GO:0043983) | 2.86869083 |
119 | mitotic spindle checkpoint (GO:0071174) | 2.85896397 |
120 | ATP-dependent chromatin remodeling (GO:0043044) | 2.85124515 |
121 | modulation by virus of host process (GO:0019054) | 2.82940399 |
122 | protein export from nucleus (GO:0006611) | 2.78759750 |
123 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 2.78491171 |
124 | negative regulation of cell killing (GO:0031342) | 2.78491171 |
125 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 2.77050856 |
126 | trophectodermal cell differentiation (GO:0001829) | 2.75061538 |
127 | protein complex localization (GO:0031503) | 2.72299926 |
128 | embryonic process involved in female pregnancy (GO:0060136) | 2.71881347 |
129 | cellular protein complex localization (GO:0034629) | 2.68130486 |
130 | cellular response to epidermal growth factor stimulus (GO:0071364) | 2.67646021 |
131 | cellular hyperosmotic response (GO:0071474) | 2.66947239 |
132 | adherens junction assembly (GO:0034333) | 2.65555507 |
133 | negative thymic T cell selection (GO:0045060) | 2.65323331 |
134 | response to interleukin-4 (GO:0070670) | 2.64070740 |
135 | antigen processing and presentation of endogenous antigen (GO:0019883) | 2.62130244 |
136 | glucocorticoid receptor signaling pathway (GO:0042921) | 2.61560161 |
137 | modulation by symbiont of host cellular process (GO:0044068) | 2.61400266 |
138 | regulation of early endosome to late endosome transport (GO:2000641) | 2.59718515 |
139 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 2.59167181 |
140 | positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling | 2.57291008 |
141 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 2.55732059 |
142 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 2.55732059 |
143 | modulation by symbiont of host immune response (GO:0052553) | 2.55732059 |
144 | positive regulation by symbiont of host defense response (GO:0052509) | 2.55732059 |
145 | modulation by symbiont of host defense response (GO:0052031) | 2.55732059 |
146 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 2.55732059 |
147 | NIK/NF-kappaB signaling (GO:0038061) | 2.55562185 |
148 | regulation of mRNA stability (GO:0043488) | 2.54863693 |
149 | focal adhesion assembly (GO:0048041) | 2.52994365 |
150 | cell-substrate adherens junction assembly (GO:0007045) | 2.52994365 |
151 | T cell selection (GO:0045058) | 2.52167644 |
152 | regulation of gamma-delta T cell differentiation (GO:0045586) | 2.51479213 |
153 | pentose-phosphate shunt (GO:0006098) | 2.51298123 |
154 | response to muramyl dipeptide (GO:0032495) | 2.50427059 |
155 | regulation of RNA stability (GO:0043487) | 2.49986962 |
156 | regulation of translational termination (GO:0006449) | 2.49692144 |
157 | protein localization to endosome (GO:0036010) | 2.48783696 |
158 | Golgi transport vesicle coating (GO:0048200) | 2.48509815 |
159 | COPI coating of Golgi vesicle (GO:0048205) | 2.48509815 |
160 | negative T cell selection (GO:0043383) | 2.46639997 |
161 | regulation of type I interferon-mediated signaling pathway (GO:0060338) | 2.46359874 |
162 | regulation of gamma-delta T cell activation (GO:0046643) | 2.45868918 |
163 | leukocyte aggregation (GO:0070486) | 2.45195511 |
164 | activation of Rac GTPase activity (GO:0032863) | 2.44419114 |
165 | response to laminar fluid shear stress (GO:0034616) | 2.43967959 |
166 | maternal placenta development (GO:0001893) | 2.43113731 |
167 | DNA packaging (GO:0006323) | 2.41456741 |
168 | positive regulation of gene expression, epigenetic (GO:0045815) | 2.40810955 |
169 | positive regulation by host of viral transcription (GO:0043923) | 2.39461601 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 9.22612462 |
2 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 5.32679383 |
3 | * MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.89410862 |
4 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.75834661 |
5 | * EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.43948434 |
6 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 3.43013171 |
7 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 3.08929549 |
8 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.93304820 |
9 | MYC_22102868_ChIP-Seq_BL_Human | 2.69116124 |
10 | * MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.56266810 |
11 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.35795209 |
12 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.35389609 |
13 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.33873427 |
14 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 2.14022650 |
15 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.13287698 |
16 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.10215582 |
17 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 2.08313796 |
18 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.06518575 |
19 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 2.06348628 |
20 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.06163468 |
21 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 2.05893767 |
22 | CIITA_25753668_ChIP-Seq_RAJI_Human | 2.04714216 |
23 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.99943702 |
24 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.98430838 |
25 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.95463659 |
26 | * MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.90161878 |
27 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.87572379 |
28 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.83789361 |
29 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.81807658 |
30 | MAF_26560356_Chip-Seq_TH1_Human | 1.81367417 |
31 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.78916975 |
32 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.72543914 |
33 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.71288967 |
34 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.69916748 |
35 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.68203093 |
36 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.68050787 |
37 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.67279567 |
38 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.66160518 |
39 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.66048081 |
40 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.64821489 |
41 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.64037243 |
42 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.61805209 |
43 | * THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.61423830 |
44 | * YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.59666899 |
45 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.59219754 |
46 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.57898136 |
47 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.57329793 |
48 | * VDR_23849224_ChIP-Seq_CD4+_Human | 1.55328656 |
49 | * GABP_19822575_ChIP-Seq_HepG2_Human | 1.53673007 |
50 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.53610274 |
51 | MAF_26560356_Chip-Seq_TH2_Human | 1.53567898 |
52 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.51067644 |
53 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.49009900 |
54 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.48766902 |
55 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.47969857 |
56 | * ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.44316084 |
57 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.44151851 |
58 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.44080350 |
59 | * EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.43981210 |
60 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.43092323 |
61 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.41913090 |
62 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.41849456 |
63 | NCOR1_26117541_ChIP-Seq_K562_Human | 1.41663804 |
64 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.41046722 |
65 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.40227446 |
66 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.37104476 |
67 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.36709430 |
68 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.36438186 |
69 | * TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.33478935 |
70 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.32350691 |
71 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.32226611 |
72 | KDM2B_26808549_Chip-Seq_K562_Human | 1.32173738 |
73 | * KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.30124827 |
74 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.30086194 |
75 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.29326677 |
76 | * SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.26559333 |
77 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.26418639 |
78 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 1.26180344 |
79 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.25784594 |
80 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.25193704 |
81 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.24905681 |
82 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.22205286 |
83 | * GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.21760011 |
84 | P68_20966046_ChIP-Seq_HELA_Human | 1.21246840 |
85 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.20107001 |
86 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.19915436 |
87 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.19793095 |
88 | * POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.18381856 |
89 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.18143407 |
90 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.18088495 |
91 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.16199835 |
92 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.16002282 |
93 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.15463191 |
94 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.14879093 |
95 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.14003313 |
96 | MYB_26560356_Chip-Seq_TH1_Human | 1.13874952 |
97 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.13461732 |
98 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.13161297 |
99 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.12743155 |
100 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.12620807 |
101 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.12133126 |
102 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.11008942 |
103 | * TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.10796425 |
104 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.10716049 |
105 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.10537814 |
106 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.09902606 |
107 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.09336027 |
108 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.09336027 |
109 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.09336027 |
110 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.08538073 |
111 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.08293472 |
112 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.08255518 |
113 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.07536711 |
114 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.06156224 |
115 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.05661272 |
116 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.04589973 |
117 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.04403476 |
118 | * ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.04348191 |
119 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.04229267 |
120 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.03515075 |
121 | * SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.03083215 |
122 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.02412477 |
123 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.01319234 |
124 | MYB_26560356_Chip-Seq_TH2_Human | 1.01043161 |
125 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.00622005 |
126 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.00187986 |
127 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.99794650 |
128 | SMC4_20622854_ChIP-Seq_HELA_Human | 0.99718770 |
129 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 0.98807184 |
130 | ELK1_19687146_ChIP-ChIP_HELA_Human | 0.98692491 |
131 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 0.98457701 |
132 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.98401657 |
133 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 0.97981495 |
134 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 0.97542279 |
135 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 0.97140518 |
136 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 0.97131943 |
137 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 0.96511436 |
138 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.96168640 |
139 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 0.95907662 |
140 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 0.95380321 |
141 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 0.95122046 |
142 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 0.94250731 |
143 | UTX_26944678_Chip-Seq_JUKART_Human | 0.93920224 |
144 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 0.93617835 |
145 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.93307025 |
146 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.92757759 |
147 | KDM2B_26808549_Chip-Seq_DND41_Human | 0.91573462 |
148 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 0.90015045 |
149 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 0.87820590 |
150 | TCF3_18692474_ChIP-Seq_MESCs_Mouse | 0.87764103 |
151 | CHD1_26751641_Chip-Seq_LNCaP_Human | 0.86423296 |
152 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 0.85939806 |
153 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 0.85695682 |
154 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 0.85669067 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0010094_abnormal_chromosome_stability | 4.05661764 |
2 | MP0003111_abnormal_nucleus_morphology | 4.00817666 |
3 | MP0003693_abnormal_embryo_hatching | 3.93027309 |
4 | MP0004957_abnormal_blastocyst_morpholog | 3.73054649 |
5 | MP0003077_abnormal_cell_cycle | 3.65443590 |
6 | MP0008057_abnormal_DNA_replication | 3.44752042 |
7 | MP0003123_paternal_imprinting | 2.87765109 |
8 | MP0005451_abnormal_body_composition | 2.77158383 |
9 | MP0008007_abnormal_cellular_replicative | 2.47299604 |
10 | MP0002877_abnormal_melanocyte_morpholog | 2.45397170 |
11 | MP0008058_abnormal_DNA_repair | 2.45202884 |
12 | MP0001730_embryonic_growth_arrest | 2.44201379 |
13 | MP0003303_peritoneal_inflammation | 2.41394326 |
14 | MP0000350_abnormal_cell_proliferation | 2.36775834 |
15 | MP0008932_abnormal_embryonic_tissue | 2.28982683 |
16 | MP0010030_abnormal_orbit_morphology | 2.28073146 |
17 | MP0010352_gastrointestinal_tract_polyps | 2.26812947 |
18 | MP0003436_decreased_susceptibility_to | 2.16874295 |
19 | MP0005076_abnormal_cell_differentiation | 2.01337648 |
20 | MP0001672_abnormal_embryogenesis/_devel | 2.01162852 |
21 | MP0005380_embryogenesis_phenotype | 2.01162852 |
22 | MP0003300_gastrointestinal_ulcer | 1.99960700 |
23 | MP0002085_abnormal_embryonic_tissue | 1.94945983 |
24 | MP0002084_abnormal_developmental_patter | 1.93165001 |
25 | MP0008877_abnormal_DNA_methylation | 1.92665057 |
26 | MP0003121_genomic_imprinting | 1.91349893 |
27 | MP0002396_abnormal_hematopoietic_system | 1.91348463 |
28 | MP0001697_abnormal_embryo_size | 1.90172827 |
29 | MP0008260_abnormal_autophagy | 1.90085403 |
30 | MP0004197_abnormal_fetal_growth/weight/ | 1.88269463 |
31 | MP0004185_abnormal_adipocyte_glucose | 1.86123965 |
32 | MP0003984_embryonic_growth_retardation | 1.83659833 |
33 | MP0000537_abnormal_urethra_morphology | 1.83510096 |
34 | MP0002088_abnormal_embryonic_growth/wei | 1.81623495 |
35 | MP0010307_abnormal_tumor_latency | 1.81378442 |
36 | MP0003890_abnormal_embryonic-extraembry | 1.79666122 |
37 | MP0004808_abnormal_hematopoietic_stem | 1.71744730 |
38 | MP0003283_abnormal_digestive_organ | 1.71210551 |
39 | MP0002796_impaired_skin_barrier | 1.67794452 |
40 | MP0002080_prenatal_lethality | 1.66766680 |
41 | MP0000678_abnormal_parathyroid_gland | 1.64844702 |
42 | MP0003119_abnormal_digestive_system | 1.64734635 |
43 | MP0004947_skin_inflammation | 1.64039996 |
44 | MP0002086_abnormal_extraembryonic_tissu | 1.62599538 |
45 | MP0001348_abnormal_lacrimal_gland | 1.59480620 |
46 | MP0009278_abnormal_bone_marrow | 1.57883401 |
47 | MP0009053_abnormal_anal_canal | 1.55598263 |
48 | MP0003091_abnormal_cell_migration | 1.52182975 |
49 | MP0003453_abnormal_keratinocyte_physiol | 1.51930442 |
50 | MP0001293_anophthalmia | 1.50558193 |
51 | MP0002009_preneoplasia | 1.50468761 |
52 | MP0000490_abnormal_crypts_of | 1.48641108 |
53 | MP0003567_abnormal_fetal_cardiomyocyte | 1.41913624 |
54 | MP0001835_abnormal_antigen_presentation | 1.40373011 |
55 | MP0001849_ear_inflammation | 1.40219767 |
56 | MP0000685_abnormal_immune_system | 1.39843452 |
57 | MP0000858_altered_metastatic_potential | 1.38944210 |
58 | MP0002653_abnormal_ependyma_morphology | 1.38383655 |
59 | MP0003786_premature_aging | 1.37007834 |
60 | MP0003172_abnormal_lysosome_physiology | 1.36293147 |
61 | MP0004381_abnormal_hair_follicle | 1.34080624 |
62 | MP0000313_abnormal_cell_death | 1.33977376 |
63 | MP0004133_heterotaxia | 1.30965762 |
64 | MP0004858_abnormal_nervous_system | 1.30392526 |
65 | MP0005623_abnormal_meninges_morphology | 1.29772308 |
66 | MP0005000_abnormal_immune_tolerance | 1.27811775 |
67 | MP0001800_abnormal_humoral_immune | 1.27400702 |
68 | MP0003705_abnormal_hypodermis_morpholog | 1.26743659 |
69 | MP0002420_abnormal_adaptive_immunity | 1.24962177 |
70 | MP0002429_abnormal_blood_cell | 1.24877309 |
71 | MP0005666_abnormal_adipose_tissue | 1.23683462 |
72 | MP0001819_abnormal_immune_cell | 1.22846636 |
73 | MP0000716_abnormal_immune_system | 1.21944873 |
74 | MP0005501_abnormal_skin_physiology | 1.21218444 |
75 | MP0000703_abnormal_thymus_morphology | 1.20547726 |
76 | MP0005387_immune_system_phenotype | 1.20062862 |
77 | MP0001790_abnormal_immune_system | 1.20062862 |
78 | MP0000428_abnormal_craniofacial_morphol | 1.17656297 |
79 | MP0005058_abnormal_lysosome_morphology | 1.16613699 |
80 | MP0002019_abnormal_tumor_incidence | 1.16237916 |
81 | MP0000689_abnormal_spleen_morphology | 1.11534837 |
82 | MP0005409_darkened_coat_color | 1.11374105 |
83 | MP0003941_abnormal_skin_development | 1.10830662 |
84 | MP0005025_abnormal_response_to | 1.09695293 |
85 | MP0000733_abnormal_muscle_development | 1.09496508 |
86 | MP0002723_abnormal_immune_serum | 1.09008640 |
87 | MP0005464_abnormal_platelet_physiology | 1.07830862 |
88 | MP0002452_abnormal_antigen_presenting | 1.07676619 |
89 | MP0003115_abnormal_respiratory_system | 1.06986336 |
90 | MP0001873_stomach_inflammation | 1.06924151 |
91 | MP0005671_abnormal_response_to | 1.06552335 |
92 | MP0002111_abnormal_tail_morphology | 1.06523947 |
93 | MP0002405_respiratory_system_inflammati | 1.04806754 |
94 | MP0003315_abnormal_perineum_morphology | 1.03481829 |
95 | MP0009672_abnormal_birth_weight | 1.03360703 |
96 | MP0001851_eye_inflammation | 1.03056730 |
97 | MP0002419_abnormal_innate_immunity | 1.02922991 |
98 | MP0002166_altered_tumor_susceptibility | 1.02529995 |
99 | MP0003861_abnormal_nervous_system | 1.02234136 |
100 | MP0003937_abnormal_limbs/digits/tail_de | 1.01916146 |
101 | MP0002132_abnormal_respiratory_system | 1.01741829 |
102 | MP0001545_abnormal_hematopoietic_system | 0.99606084 |
103 | MP0005397_hematopoietic_system_phenotyp | 0.99606084 |
104 | MP0003935_abnormal_craniofacial_develop | 0.98481197 |
105 | MP0004264_abnormal_extraembryonic_tissu | 0.98322540 |
106 | MP0002210_abnormal_sex_determination | 0.97132587 |
107 | MP0003122_maternal_imprinting | 0.96944301 |
108 | MP0009703_decreased_birth_body | 0.94688235 |
109 | MP0010234_abnormal_vibrissa_follicle | 0.94552424 |
110 | MP0002092_abnormal_eye_morphology | 0.93965518 |
111 | MP0004233_abnormal_muscle_weight | 0.93470117 |
112 | MP0002932_abnormal_joint_morphology | 0.91803949 |
113 | MP0008961_abnormal_basal_metabolism | 0.91516341 |
114 | MP0002697_abnormal_eye_size | 0.90718528 |
115 | MP0010630_abnormal_cardiac_muscle | 0.89238704 |
116 | MP0003828_pulmonary_edema | 0.88910410 |
117 | MP0001145_abnormal_male_reproductive | 0.88898348 |
118 | MP0001346_abnormal_lacrimal_gland | 0.88602111 |
119 | MP0001915_intracranial_hemorrhage | 0.88416906 |
120 | MP0000432_abnormal_head_morphology | 0.87594700 |
121 | MP0000049_abnormal_middle_ear | 0.87160365 |
122 | MP0003763_abnormal_thymus_physiology | 0.86889799 |
123 | MP0002398_abnormal_bone_marrow | 0.86533292 |
124 | MP0005375_adipose_tissue_phenotype | 0.86389490 |
125 | MP0009333_abnormal_splenocyte_physiolog | 0.85674976 |
126 | MP0005023_abnormal_wound_healing | 0.85633860 |
127 | MP0002925_abnormal_cardiovascular_devel | 0.85417306 |
128 | MP0010155_abnormal_intestine_physiology | 0.84656735 |
129 | MP0001286_abnormal_eye_development | 0.84527631 |
130 | MP0003566_abnormal_cell_adhesion | 0.83456403 |
131 | MP0002089_abnormal_postnatal_growth/wei | 0.83127315 |
132 | MP0003385_abnormal_body_wall | 0.80758024 |
133 | MP0002722_abnormal_immune_system | 0.80268519 |
134 | MP0003942_abnormal_urinary_system | 0.79269633 |
135 | MP0002116_abnormal_craniofacial_bone | 0.78329964 |
136 | MP0008789_abnormal_olfactory_epithelium | 0.76755315 |
137 | MP0003787_abnormal_imprinting | 0.75129276 |
138 | MP0003755_abnormal_palate_morphology | 0.73910075 |
139 | MP0008770_decreased_survivor_rate | 0.73841524 |
140 | MP0002114_abnormal_axial_skeleton | 0.73418604 |
141 | MP0003943_abnormal_hepatobiliary_system | 0.72564896 |
142 | MP0006292_abnormal_olfactory_placode | 0.71892452 |
143 | MP0002282_abnormal_trachea_morphology | 0.71685053 |
144 | MP0005384_cellular_phenotype | 0.71232384 |
145 | MP0005621_abnormal_cell_physiology | 0.70861654 |
146 | MP0001929_abnormal_gametogenesis | 0.69135576 |
147 | MP0000653_abnormal_sex_gland | 0.68317178 |
148 | MP0002075_abnormal_coat/hair_pigmentati | 0.67820276 |
149 | MP0005394_taste/olfaction_phenotype | 0.67349055 |
150 | MP0005499_abnormal_olfactory_system | 0.67349055 |
151 | MP0002938_white_spotting | 0.66995171 |
152 | MP0002102_abnormal_ear_morphology | 0.66427959 |
153 | MP0002081_perinatal_lethality | 0.66102768 |
154 | MP0002249_abnormal_larynx_morphology | 0.66058043 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Ependymoma (HP:0002888) | 3.67827402 |
2 | Selective tooth agenesis (HP:0001592) | 3.26398675 |
3 | Colon cancer (HP:0003003) | 3.19529995 |
4 | Medulloblastoma (HP:0002885) | 3.19497121 |
5 | Increased nuchal translucency (HP:0010880) | 3.13091224 |
6 | Abnormal number of incisors (HP:0011064) | 3.12343170 |
7 | Reticulocytopenia (HP:0001896) | 3.11715043 |
8 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.99731199 |
9 | Short 4th metacarpal (HP:0010044) | 2.99731199 |
10 | Patellar aplasia (HP:0006443) | 2.94434805 |
11 | Renal duplication (HP:0000075) | 2.93377171 |
12 | Hyperacusis (HP:0010780) | 2.91154293 |
13 | Urethral obstruction (HP:0000796) | 2.86628140 |
14 | Obstructive sleep apnea (HP:0002870) | 2.79472560 |
15 | Birth length less than 3rd percentile (HP:0003561) | 2.78995150 |
16 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.76844722 |
17 | Abnormality of the astrocytes (HP:0100707) | 2.68203736 |
18 | Astrocytoma (HP:0009592) | 2.68203736 |
19 | Abnormality of the labia minora (HP:0012880) | 2.63913882 |
20 | Increased connective tissue (HP:0009025) | 2.63219470 |
21 | Degeneration of anterior horn cells (HP:0002398) | 2.58309765 |
22 | Abnormality of the anterior horn cell (HP:0006802) | 2.58309765 |
23 | Progressive muscle weakness (HP:0003323) | 2.58186895 |
24 | Eczematoid dermatitis (HP:0000976) | 2.56767492 |
25 | Insomnia (HP:0100785) | 2.56448357 |
26 | Overlapping toe (HP:0001845) | 2.55194085 |
27 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 2.54077821 |
28 | Long palpebral fissure (HP:0000637) | 2.53541814 |
29 | Proximal placement of thumb (HP:0009623) | 2.52575723 |
30 | Chromsome breakage (HP:0040012) | 2.51109886 |
31 | Cellulitis (HP:0100658) | 2.48367537 |
32 | Deviation of the thumb (HP:0009603) | 2.47270014 |
33 | Deep palmar crease (HP:0006191) | 2.46573205 |
34 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.46458094 |
35 | Basal cell carcinoma (HP:0002671) | 2.44388945 |
36 | Disproportionate tall stature (HP:0001519) | 2.43570120 |
37 | Missing ribs (HP:0000921) | 2.43122362 |
38 | Rhabdomyosarcoma (HP:0002859) | 2.42337789 |
39 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 2.37326971 |
40 | Progressive external ophthalmoplegia (HP:0000590) | 2.36818847 |
41 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 2.36813681 |
42 | Absent thumb (HP:0009777) | 2.35870351 |
43 | Neoplasm of striated muscle (HP:0009728) | 2.34085110 |
44 | 11 pairs of ribs (HP:0000878) | 2.33230498 |
45 | Dysmetric saccades (HP:0000641) | 2.32498706 |
46 | Glioma (HP:0009733) | 2.30827958 |
47 | Meckel diverticulum (HP:0002245) | 2.30396561 |
48 | Abnormality of the phalanges of the hallux (HP:0010057) | 2.28644787 |
49 | Long eyelashes (HP:0000527) | 2.28269070 |
50 | Abnormality of the ileum (HP:0001549) | 2.26890875 |
51 | Ectopic kidney (HP:0000086) | 2.26412757 |
52 | Volvulus (HP:0002580) | 2.25808345 |
53 | Abnormality of oral frenula (HP:0000190) | 2.25550393 |
54 | Segmental peripheral demyelination/remyelination (HP:0003481) | 2.24814831 |
55 | Oral leukoplakia (HP:0002745) | 2.24093121 |
56 | Increased IgE level (HP:0003212) | 2.23615650 |
57 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.23431520 |
58 | Slow saccadic eye movements (HP:0000514) | 2.23088386 |
59 | Absent radius (HP:0003974) | 2.22932581 |
60 | Abdominal situs inversus (HP:0003363) | 2.22455279 |
61 | Abnormality of abdominal situs (HP:0011620) | 2.22455279 |
62 | Broad face (HP:0000283) | 2.21922398 |
63 | Abnormality of chromosome stability (HP:0003220) | 2.21261328 |
64 | Facial hemangioma (HP:0000329) | 2.19414179 |
65 | Ankyloglossia (HP:0010296) | 2.17741700 |
66 | Atresia of the external auditory canal (HP:0000413) | 2.17589356 |
67 | Breast hypoplasia (HP:0003187) | 2.16105349 |
68 | Duodenal stenosis (HP:0100867) | 2.14455042 |
69 | Small intestinal stenosis (HP:0012848) | 2.14455042 |
70 | Fatigue (HP:0012378) | 2.14318427 |
71 | Abnormality of the 4th metacarpal (HP:0010012) | 2.14142516 |
72 | Distal lower limb amyotrophy (HP:0008944) | 2.11907422 |
73 | Peripheral hypomyelination (HP:0007182) | 2.11830358 |
74 | Broad distal phalanx of finger (HP:0009836) | 2.10949343 |
75 | Myelodysplasia (HP:0002863) | 2.10748745 |
76 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.10662042 |
77 | Neoplasm of the pancreas (HP:0002894) | 2.10500914 |
78 | Aplasia involving forearm bones (HP:0009822) | 2.08496915 |
79 | Absent forearm bone (HP:0003953) | 2.08496915 |
80 | Neoplasm of the oral cavity (HP:0100649) | 2.08057990 |
81 | Impulsivity (HP:0100710) | 2.07644785 |
82 | Dislocated radial head (HP:0003083) | 2.05651925 |
83 | Ulnar bowing (HP:0003031) | 2.05021563 |
84 | High anterior hairline (HP:0009890) | 2.04843075 |
85 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 2.04421077 |
86 | Recurrent viral infections (HP:0004429) | 2.04386646 |
87 | Metaphyseal cupping (HP:0003021) | 2.03776319 |
88 | Trigonocephaly (HP:0000243) | 2.03501212 |
89 | Achilles tendon contracture (HP:0001771) | 2.02978872 |
90 | Abnormality of the preputium (HP:0100587) | 2.00990701 |
91 | Abnormality of the carotid arteries (HP:0005344) | 1.99578786 |
92 | Bowel incontinence (HP:0002607) | 1.99106504 |
93 | Spinal cord lesions (HP:0100561) | 1.98888836 |
94 | Syringomyelia (HP:0003396) | 1.98888836 |
95 | Rib fusion (HP:0000902) | 1.98564981 |
96 | Cafe-au-lait spot (HP:0000957) | 1.97626839 |
97 | Malignant gastrointestinal tract tumors (HP:0006749) | 1.97483495 |
98 | Gastrointestinal carcinoma (HP:0002672) | 1.97483495 |
99 | Prominent nose (HP:0000448) | 1.97088172 |
100 | Gastrointestinal inflammation (HP:0004386) | 1.96526800 |
101 | Patellar dislocation (HP:0002999) | 1.96378509 |
102 | Broad palm (HP:0001169) | 1.95487070 |
103 | High pitched voice (HP:0001620) | 1.95161844 |
104 | Abnormal lung lobation (HP:0002101) | 1.94495871 |
105 | Abnormal number of erythroid precursors (HP:0012131) | 1.93925771 |
106 | Tracheoesophageal fistula (HP:0002575) | 1.93852991 |
107 | Elfin facies (HP:0004428) | 1.93076950 |
108 | Abnormal gallbladder physiology (HP:0012438) | 1.93026773 |
109 | Cholecystitis (HP:0001082) | 1.93026773 |
110 | Renovascular hypertension (HP:0100817) | 1.91909188 |
111 | Abnormal large intestine physiology (HP:0012700) | 1.91249855 |
112 | Abnormality of the fingertips (HP:0001211) | 1.90229908 |
113 | Overriding aorta (HP:0002623) | 1.90130612 |
114 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 1.90026924 |
115 | Recurrent abscess formation (HP:0002722) | 1.89532171 |
116 | Skull defect (HP:0001362) | 1.88870857 |
117 | Obstructive lung disease (HP:0006536) | 1.88650178 |
118 | Chronic obstructive pulmonary disease (HP:0006510) | 1.88650178 |
119 | Flat acetabular roof (HP:0003180) | 1.87942247 |
120 | Gastrointestinal stroma tumor (HP:0100723) | 1.87750138 |
121 | Abnormality of the radial head (HP:0003995) | 1.87454166 |
122 | Abnormality of skeletal muscle fiber size (HP:0012084) | 1.87109269 |
123 | Colitis (HP:0002583) | 1.86713327 |
124 | Carpal bone hypoplasia (HP:0001498) | 1.85519668 |
125 | Skin tags (HP:0010609) | 1.84950651 |
126 | Abnormality of the thoracic spine (HP:0100711) | 1.83665965 |
127 | Increased variability in muscle fiber diameter (HP:0003557) | 1.83270571 |
128 | Broad thumb (HP:0011304) | 1.82814304 |
129 | Reticulocytosis (HP:0001923) | 1.82721363 |
130 | Hypertensive crisis (HP:0100735) | 1.81941483 |
131 | Supernumerary bones of the axial skeleton (HP:0009144) | 1.81748603 |
132 | Squamous cell carcinoma (HP:0002860) | 1.81215658 |
133 | Megalocornea (HP:0000485) | 1.80741003 |
134 | Supernumerary ribs (HP:0005815) | 1.80223312 |
135 | Agnosia (HP:0010524) | 1.79722657 |
136 | Abnormality of the duodenum (HP:0002246) | 1.79314166 |
137 | Abnormality of the salivary glands (HP:0010286) | 1.76869520 |
138 | Preauricular skin tag (HP:0000384) | 1.76293034 |
139 | Aplasia/Hypoplasia of the thymus (HP:0010515) | 1.76242036 |
140 | Pointed chin (HP:0000307) | 1.76180116 |
141 | Angiofibromas (HP:0010615) | 1.75445817 |
142 | Adenoma sebaceum (HP:0009720) | 1.75445817 |
143 | Cutis marmorata (HP:0000965) | 1.75342737 |
144 | Persistence of primary teeth (HP:0006335) | 1.75137274 |
145 | Abnormality of the columella (HP:0009929) | 1.74523821 |
146 | Pelvic girdle muscle weakness (HP:0003749) | 1.73731271 |
147 | Abnormality of the Achilles tendon (HP:0005109) | 1.73456972 |
148 | Truncus arteriosus (HP:0001660) | 1.73283999 |
149 | Abnormality of the calcaneus (HP:0008364) | 1.72515526 |
150 | Supernumerary spleens (HP:0009799) | 1.72475331 |
151 | Abnormality of the distal phalanges of the toes (HP:0010182) | 1.71799819 |
152 | Ragged-red muscle fibers (HP:0003200) | 1.71703728 |
153 | Aplasia/hypoplasia of the humerus (HP:0006507) | 1.71554007 |
154 | Seborrheic dermatitis (HP:0001051) | 1.70998131 |
155 | Viral hepatitis (HP:0006562) | 1.70981354 |
156 | Meningitis (HP:0001287) | 1.70863611 |
157 | Broad alveolar ridges (HP:0000187) | 1.70732264 |
158 | Trismus (HP:0000211) | 1.70429664 |
159 | Flat cornea (HP:0007720) | 1.69315912 |
160 | Agammaglobulinemia (HP:0004432) | 1.69234474 |
161 | Recurrent bacterial skin infections (HP:0005406) | 1.68456012 |
162 | Bowel diverticulosis (HP:0005222) | 1.68427767 |
163 | Thoracic kyphosis (HP:0002942) | 1.68147589 |
164 | Pseudobulbar signs (HP:0002200) | 1.67020513 |
165 | Esophageal atresia (HP:0002032) | 1.66884835 |
166 | Polygenic inheritance (HP:0010982) | 1.63927236 |
167 | Abnormality of macrophages (HP:0004311) | 1.63880496 |
168 | Progressive hearing impairment (HP:0001730) | 1.60176731 |
169 | Inflammation of the large intestine (HP:0002037) | 1.59087718 |
170 | Abnormality of reticulocytes (HP:0004312) | 1.59047024 |
171 | Difficulty climbing stairs (HP:0003551) | 1.56528239 |
172 | Mediastinal lymphadenopathy (HP:0100721) | 1.56412627 |
173 | Arnold-Chiari malformation (HP:0002308) | 1.55685399 |
174 | Genu recurvatum (HP:0002816) | 1.55286409 |
175 | Premature skin wrinkling (HP:0100678) | 1.53427635 |
176 | Gingivitis (HP:0000230) | 1.53342631 |
177 | Self-mutilation (HP:0000742) | 1.52539941 |
178 | Protrusio acetabuli (HP:0003179) | 1.52447144 |
179 | Sparse lateral eyebrow (HP:0005338) | 1.52237193 |
180 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 1.50712174 |
181 | Annular pancreas (HP:0001734) | 1.50507058 |
182 | Emphysema (HP:0002097) | 1.50305782 |
183 | Obsessive-compulsive behavior (HP:0000722) | 1.48871949 |
184 | Vertebral compression fractures (HP:0002953) | 1.48221298 |
185 | Cerebral aneurysm (HP:0004944) | 1.48160142 |
Rank | Gene Set | Z-score |
---|---|---|
1 | CDC7 | 4.23512181 |
2 | CDK12 | 4.18186849 |
3 | PRPF4B | 3.92541335 |
4 | SMG1 | 3.88601588 |
5 | EEF2K | 3.35812161 |
6 | BUB1 | 3.28276675 |
7 | WEE1 | 3.06763404 |
8 | NEK2 | 2.86340973 |
9 | NEK1 | 2.79029910 |
10 | MAP3K10 | 2.72013320 |
11 | TTK | 2.50115157 |
12 | TSSK6 | 2.33243568 |
13 | BRD4 | 2.13961060 |
14 | PASK | 2.07292408 |
15 | STK10 | 1.99639471 |
16 | ERN1 | 1.99144303 |
17 | MAP3K13 | 1.92713097 |
18 | RIPK4 | 1.89980323 |
19 | CDK7 | 1.89630576 |
20 | SIK1 | 1.86843643 |
21 | RPS6KB2 | 1.83768336 |
22 | PLK1 | 1.79541374 |
23 | MKNK1 | 1.75374631 |
24 | PKN2 | 1.73957070 |
25 | ATR | 1.72410441 |
26 | CDK4 | 1.70896974 |
27 | FGFR4 | 1.63465593 |
28 | KSR2 | 1.61683883 |
29 | TRIB3 | 1.60977395 |
30 | SRPK1 | 1.56303411 |
31 | ALK | 1.49193353 |
32 | IRAK3 | 1.45672221 |
33 | CHEK1 | 1.45536012 |
34 | TESK2 | 1.42310409 |
35 | TAOK1 | 1.42220080 |
36 | BRSK2 | 1.40984060 |
37 | AURKB | 1.40747667 |
38 | MAP3K8 | 1.38998232 |
39 | TGFBR1 | 1.38315609 |
40 | CHEK2 | 1.34983278 |
41 | MKNK2 | 1.34511625 |
42 | SCYL2 | 1.33968170 |
43 | BRSK1 | 1.31043789 |
44 | DYRK3 | 1.29190271 |
45 | PLK3 | 1.28521445 |
46 | PAK4 | 1.23220822 |
47 | AURKA | 1.12568939 |
48 | MAP3K1 | 1.10254651 |
49 | ICK | 1.10182592 |
50 | EIF2AK1 | 1.09097181 |
51 | NME2 | 1.08649665 |
52 | RPS6KA4 | 1.07798814 |
53 | CDK2 | 1.07211206 |
54 | MAP3K3 | 1.06166589 |
55 | MTOR | 1.05589504 |
56 | MAP3K14 | 1.03641078 |
57 | FES | 1.03335921 |
58 | RIPK1 | 1.02164463 |
59 | MAP3K9 | 1.01788506 |
60 | IRAK4 | 1.01385482 |
61 | CDK6 | 1.01055018 |
62 | MELK | 0.99731784 |
63 | PLK4 | 0.97725674 |
64 | ATM | 0.97658565 |
65 | EPHB1 | 0.96174513 |
66 | TYRO3 | 0.95080802 |
67 | MAP4K1 | 0.93586404 |
68 | CLK1 | 0.92983375 |
69 | MARK2 | 0.92807282 |
70 | TLK1 | 0.91815582 |
71 | PDGFRA | 0.91404892 |
72 | LRRK2 | 0.89194477 |
73 | EPHA2 | 0.87926128 |
74 | HIPK2 | 0.85666040 |
75 | LATS2 | 0.85230407 |
76 | STK4 | 0.79962641 |
77 | CDK1 | 0.79502730 |
78 | PRKD3 | 0.78924886 |
79 | CDK8 | 0.76365095 |
80 | TYK2 | 0.76315098 |
81 | SIK3 | 0.75329629 |
82 | ACVR1B | 0.74276983 |
83 | PRKD2 | 0.74044407 |
84 | PIM1 | 0.73857034 |
85 | IRAK2 | 0.73529653 |
86 | CAMK1D | 0.72054951 |
87 | FGFR1 | 0.71630355 |
88 | CSK | 0.69160312 |
89 | ZAP70 | 0.67709333 |
90 | MAPK11 | 0.67650825 |
91 | PTK6 | 0.67599957 |
92 | KSR1 | 0.65959747 |
93 | BMX | 0.65854938 |
94 | CDC42BPA | 0.65604792 |
95 | AKT2 | 0.62949806 |
96 | UHMK1 | 0.62771680 |
97 | PAK1 | 0.62326723 |
98 | JAK3 | 0.62079185 |
99 | PAK2 | 0.60783476 |
100 | PDPK1 | 0.60525032 |
101 | BRAF | 0.60006023 |
102 | VRK1 | 0.59761476 |
103 | MAP2K2 | 0.58347788 |
104 | CDK9 | 0.56603263 |
105 | PNCK | 0.56379481 |
106 | ARAF | 0.56302916 |
107 | CSNK2A2 | 0.53638955 |
108 | MAP2K3 | 0.53570548 |
109 | HCK | 0.53465969 |
110 | CSNK1E | 0.51567558 |
111 | PRKCI | 0.48364297 |
112 | CAMK1G | 0.47220310 |
113 | VRK2 | 0.45461639 |
114 | PRKDC | 0.45408497 |
115 | MAPK14 | 0.45298522 |
116 | PDK1 | 0.44325595 |
117 | RPS6KA2 | 0.44098880 |
118 | RAF1 | 0.43417974 |
119 | STK3 | 0.42976007 |
120 | GRK6 | 0.42908313 |
121 | FGFR3 | 0.42375623 |
122 | SIK2 | 0.41863467 |
123 | CCNB1 | 0.41254139 |
124 | TAOK2 | 0.40447539 |
125 | MARK3 | 0.39438095 |
126 | RPS6KC1 | 0.39163196 |
127 | RPS6KL1 | 0.39163196 |
128 | MOS | 0.38844116 |
129 | RPS6KA1 | 0.38815517 |
130 | PRKCH | 0.38804357 |
131 | TTN | 0.38396440 |
132 | CSNK2A1 | 0.37548687 |
133 | MAP3K7 | 0.37378849 |
134 | RET | 0.37039999 |
135 | AKT1 | 0.36245746 |
136 | TNK2 | 0.36239173 |
137 | MAP3K2 | 0.35474377 |
138 | CSNK1D | 0.35307977 |
139 | TESK1 | 0.35148719 |
140 | FLT3 | 0.34940246 |
141 | MAPK10 | 0.34864706 |
142 | ILK | 0.34101915 |
143 | GSK3B | 0.32994024 |
144 | RPS6KA6 | 0.30614646 |
145 | MAPK1 | 0.29842336 |
146 | CDK11A | 0.29067953 |
147 | LATS1 | 0.27803041 |
148 | MAPKAPK2 | 0.27624161 |
149 | MAP3K11 | 0.27158033 |
150 | CHUK | 0.26058625 |
151 | BTK | 0.25986435 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DNA replication_Homo sapiens_hsa03030 | 4.47889209 |
2 | Mismatch repair_Homo sapiens_hsa03430 | 3.81068038 |
3 | * Spliceosome_Homo sapiens_hsa03040 | 3.49133004 |
4 | RNA transport_Homo sapiens_hsa03013 | 3.19894923 |
5 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.09943004 |
6 | Base excision repair_Homo sapiens_hsa03410 | 3.00682591 |
7 | Cell cycle_Homo sapiens_hsa04110 | 2.90363271 |
8 | Homologous recombination_Homo sapiens_hsa03440 | 2.57135643 |
9 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.55587159 |
10 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.54304658 |
11 | Ribosome_Homo sapiens_hsa03010 | 2.42294733 |
12 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.41721339 |
13 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 2.36879060 |
14 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 2.14035028 |
15 | RNA polymerase_Homo sapiens_hsa03020 | 2.12535957 |
16 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.00318719 |
17 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.73326782 |
18 | RNA degradation_Homo sapiens_hsa03018 | 1.69919744 |
19 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.68810982 |
20 | Basal transcription factors_Homo sapiens_hsa03022 | 1.51429946 |
21 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.49477378 |
22 | Proteasome_Homo sapiens_hsa03050 | 1.41000957 |
23 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.36334314 |
24 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.34929840 |
25 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.30309946 |
26 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.29569180 |
27 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.27840468 |
28 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.27094698 |
29 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.23169128 |
30 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.22850513 |
31 | Viral carcinogenesis_Homo sapiens_hsa05203 | 1.18723360 |
32 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.18166210 |
33 | HTLV-I infection_Homo sapiens_hsa05166 | 1.17571859 |
34 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.15088206 |
35 | Leishmaniasis_Homo sapiens_hsa05140 | 1.14583518 |
36 | Prion diseases_Homo sapiens_hsa05020 | 1.10307500 |
37 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.09493724 |
38 | Colorectal cancer_Homo sapiens_hsa05210 | 1.08291160 |
39 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.06370141 |
40 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 1.04083858 |
41 | Thyroid cancer_Homo sapiens_hsa05216 | 1.01438129 |
42 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.94495179 |
43 | Other glycan degradation_Homo sapiens_hsa00511 | 0.94291377 |
44 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.93853310 |
45 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.92988887 |
46 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.92898391 |
47 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.92876499 |
48 | Hepatitis C_Homo sapiens_hsa05160 | 0.87234199 |
49 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.86863937 |
50 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.86124452 |
51 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.85586887 |
52 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.82060440 |
53 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.82000015 |
54 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.80554194 |
55 | Adherens junction_Homo sapiens_hsa04520 | 0.79859445 |
56 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.79527267 |
57 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.78446774 |
58 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.77721596 |
59 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.77709664 |
60 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.77395641 |
61 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.76967496 |
62 | Endometrial cancer_Homo sapiens_hsa05213 | 0.76436446 |
63 | Purine metabolism_Homo sapiens_hsa00230 | 0.75782111 |
64 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.75211717 |
65 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.74753419 |
66 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.74741038 |
67 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.74310497 |
68 | Lysine degradation_Homo sapiens_hsa00310 | 0.72313847 |
69 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.69562661 |
70 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.69176393 |
71 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.68665724 |
72 | Bladder cancer_Homo sapiens_hsa05219 | 0.67762037 |
73 | Hepatitis B_Homo sapiens_hsa05161 | 0.66134304 |
74 | Long-term potentiation_Homo sapiens_hsa04720 | 0.65999817 |
75 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.65367436 |
76 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.65250771 |
77 | Pathways in cancer_Homo sapiens_hsa05200 | 0.64253192 |
78 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.62854849 |
79 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.62355295 |
80 | Viral myocarditis_Homo sapiens_hsa05416 | 0.61781162 |
81 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.61565241 |
82 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.61457693 |
83 | Shigellosis_Homo sapiens_hsa05131 | 0.61171879 |
84 | Endocytosis_Homo sapiens_hsa04144 | 0.59980469 |
85 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.59206920 |
86 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.58462502 |
87 | Tuberculosis_Homo sapiens_hsa05152 | 0.57649832 |
88 | Apoptosis_Homo sapiens_hsa04210 | 0.57393458 |
89 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.57036829 |
90 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.56826103 |
91 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.56652131 |
92 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.56316698 |
93 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.56281225 |
94 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.54967346 |
95 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.54838713 |
96 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.54669459 |
97 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.54050140 |
98 | Prostate cancer_Homo sapiens_hsa05215 | 0.53415310 |
99 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.51441084 |
100 | Platelet activation_Homo sapiens_hsa04611 | 0.51069405 |
101 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.50337547 |
102 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.45591420 |
103 | Alcoholism_Homo sapiens_hsa05034 | 0.45408207 |
104 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.44948184 |
105 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.43240069 |
106 | Glioma_Homo sapiens_hsa05214 | 0.42659500 |
107 | Legionellosis_Homo sapiens_hsa05134 | 0.42488987 |
108 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.42070733 |
109 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.41769152 |
110 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 0.40952860 |
111 | Tight junction_Homo sapiens_hsa04530 | 0.40811799 |
112 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.40591533 |
113 | Melanoma_Homo sapiens_hsa05218 | 0.39374069 |
114 | Measles_Homo sapiens_hsa05162 | 0.37807209 |
115 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.37558692 |
116 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.36610303 |
117 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.34717728 |
118 | Focal adhesion_Homo sapiens_hsa04510 | 0.33607087 |
119 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.32040271 |
120 | Influenza A_Homo sapiens_hsa05164 | 0.31611358 |
121 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.30552831 |
122 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.28247967 |
123 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.27706501 |
124 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.25491000 |
125 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.25299597 |
126 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.25225662 |
127 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.25214283 |
128 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.23454605 |
129 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.22388935 |
130 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.22230084 |
131 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.21998845 |