SF3A3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20. Alternative splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA strand elongation involved in DNA replication (GO:0006271)5.00634358
2DNA strand elongation (GO:0022616)4.77992986
3DNA unwinding involved in DNA replication (GO:0006268)4.70151818
4telomere maintenance via semi-conservative replication (GO:0032201)4.69968440
5ribosomal small subunit assembly (GO:0000028)4.61063665
6DNA replication initiation (GO:0006270)4.55921866
7DNA replication checkpoint (GO:0000076)4.35478452
8telomere maintenance via recombination (GO:0000722)4.26206876
9protein localization to kinetochore (GO:0034501)4.19374897
10maturation of SSU-rRNA (GO:0030490)4.16282254
11formation of translation preinitiation complex (GO:0001731)4.12818465
12mitotic recombination (GO:0006312)4.08021480
13nucleobase biosynthetic process (GO:0046112)3.92781421
14CENP-A containing nucleosome assembly (GO:0034080)3.84140972
15chromatin remodeling at centromere (GO:0031055)3.82321768
16establishment of viral latency (GO:0019043)3.80400729
17mitotic metaphase plate congression (GO:0007080)3.79441816
18telomere maintenance via telomere lengthening (GO:0010833)3.78468858
19DNA replication-dependent nucleosome assembly (GO:0006335)3.78110931
20DNA replication-dependent nucleosome organization (GO:0034723)3.78110931
21nucleotide-excision repair, DNA gap filling (GO:0006297)3.77967831
22DNA ligation (GO:0006266)3.77517893
23viral transcription (GO:0019083)3.77020011
24ribosomal small subunit biogenesis (GO:0042274)3.73002401
25translational termination (GO:0006415)3.71954441
26regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.71199336
27kinetochore organization (GO:0051383)3.69626603
28purine nucleobase biosynthetic process (GO:0009113)3.69373931
29DNA deamination (GO:0045006)3.62555819
30mitotic nuclear envelope disassembly (GO:0007077)3.59319163
31double-strand break repair via nonhomologous end joining (GO:0006303)3.57298097
32non-recombinational repair (GO:0000726)3.57298097
33ribosomal large subunit biogenesis (GO:0042273)3.56364708
34IMP biosynthetic process (GO:0006188)3.54478072
35ribonucleoprotein complex biogenesis (GO:0022613)3.53611513
36DNA replication-independent nucleosome organization (GO:0034724)3.53466386
37DNA replication-independent nucleosome assembly (GO:0006336)3.53466386
38ribosome biogenesis (GO:0042254)3.50906077
39somatic diversification of immune receptors via somatic mutation (GO:0002566)3.50771976
40somatic hypermutation of immunoglobulin genes (GO:0016446)3.50771976
41pore complex assembly (GO:0046931)3.50649825
42protein localization to chromosome, centromeric region (GO:0071459)3.48553504
43negative regulation of ligase activity (GO:0051352)3.46839672
44negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.46839672
45translational initiation (GO:0006413)3.41994101
46translational elongation (GO:0006414)3.40870788
47metaphase plate congression (GO:0051310)3.40667789
48tRNA aminoacylation for protein translation (GO:0006418)3.40106274
49ribosome assembly (GO:0042255)3.40069564
50DNA topological change (GO:0006265)3.39740198
51nuclear pore organization (GO:0006999)3.39357286
52kinetochore assembly (GO:0051382)3.37251273
53spliceosomal snRNP assembly (GO:0000387)3.37039084
54viral mRNA export from host cell nucleus (GO:0046784)3.36035408
55regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.35947748
56tRNA aminoacylation (GO:0043039)3.35610769
57amino acid activation (GO:0043038)3.35610769
58rRNA processing (GO:0006364)3.32568922
59negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.32444557
60mitotic spindle checkpoint (GO:0071174)3.31691504
61membrane disassembly (GO:0030397)3.30005522
62nuclear envelope disassembly (GO:0051081)3.30005522
63regulation of translational fidelity (GO:0006450)3.28259177
64regulation of chromosome segregation (GO:0051983)3.25998423
65establishment of integrated proviral latency (GO:0075713)3.25686195
66nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.25471803
67folic acid-containing compound biosynthetic process (GO:0009396)3.24759744
68mitotic sister chromatid segregation (GO:0000070)3.24280254
69rRNA metabolic process (GO:0016072)3.22018259
70attachment of spindle microtubules to kinetochore (GO:0008608)3.21898796
71SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.21794677
72maturation of 5.8S rRNA (GO:0000460)3.20679800
73histone exchange (GO:0043486)3.20611677
74nuclear pore complex assembly (GO:0051292)3.15983299
75transcription-coupled nucleotide-excision repair (GO:0006283)3.15912486
76spliceosomal complex assembly (GO:0000245)3.14220817
77regulation of nuclear cell cycle DNA replication (GO:0033262)3.13763390
78cotranslational protein targeting to membrane (GO:0006613)3.13654138
79negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.12651868
80regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.12279959
81regulation of mitotic metaphase/anaphase transition (GO:0030071)3.12279959
82IMP metabolic process (GO:0046040)3.12154770
83positive regulation of chromosome segregation (GO:0051984)3.11836467
84protein targeting to ER (GO:0045047)3.11505821
85mismatch repair (GO:0006298)3.11449527
86establishment of chromosome localization (GO:0051303)3.11401822
87regulation of centriole replication (GO:0046599)3.10835933
88DNA catabolic process, exonucleolytic (GO:0000738)3.10759685
89DNA duplex unwinding (GO:0032508)3.10000584
90deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.09868518
91proteasome assembly (GO:0043248)3.09823217
92DNA geometric change (GO:0032392)3.09607530
93anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.09423639
94regulation of mitotic spindle checkpoint (GO:1903504)3.09354757
95regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.09354757
96regulation of mitochondrial translation (GO:0070129)3.08990707
97rRNA modification (GO:0000154)3.05887068
98regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.05738186
99regulation of mitotic sister chromatid separation (GO:0010965)3.05252531
100regulation of mitotic sister chromatid segregation (GO:0033047)3.05252531
101regulation of sister chromatid segregation (GO:0033045)3.05252531
102chromosome segregation (GO:0007059)3.04632351
103positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.04096493
104regulation of double-strand break repair via homologous recombination (GO:0010569)3.03902784
105pseudouridine synthesis (GO:0001522)3.02812312
106negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.02713809
107mitotic sister chromatid cohesion (GO:0007064)3.01782061
108negative regulation of chromosome segregation (GO:0051985)3.01181766
109meiotic chromosome segregation (GO:0045132)3.00894783
110mitotic chromosome condensation (GO:0007076)3.00777051
111telomere organization (GO:0032200)2.99956161
112positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.99019956
113telomere maintenance (GO:0000723)2.98802537
114negative regulation of mitotic sister chromatid separation (GO:2000816)2.98199629
115negative regulation of mitotic sister chromatid segregation (GO:0033048)2.98199629
116negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.98199629
117negative regulation of sister chromatid segregation (GO:0033046)2.98199629
118sister chromatid segregation (GO:0000819)2.98198250
119base-excision repair (GO:0006284)2.97951088
120positive regulation of histone H3-K4 methylation (GO:0051571)2.97925497
121* RNA splicing, via transesterification reactions (GO:0000375)2.97533952
122* mRNA splicing, via spliceosome (GO:0000398)2.97024534
123* RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.97024534
124G1/S transition of mitotic cell cycle (GO:0000082)2.96562664
125cell cycle G1/S phase transition (GO:0044843)2.96562664
126spindle checkpoint (GO:0031577)2.95982611
127cellular protein complex disassembly (GO:0043624)2.95622296
128viral life cycle (GO:0019058)2.95191629
129spindle assembly checkpoint (GO:0071173)2.94649087
130regulation of spindle organization (GO:0090224)2.94644716
131establishment of protein localization to endoplasmic reticulum (GO:0072599)2.93596931
132mitotic spindle assembly checkpoint (GO:0007094)2.91305789
133negative regulation of RNA splicing (GO:0033119)2.91024667
134protein localization to endoplasmic reticulum (GO:0070972)2.90922730

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.04790664
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.37498602
3FOXM1_23109430_ChIP-Seq_U2OS_Human3.83659958
4E2F4_17652178_ChIP-ChIP_JURKAT_Human3.81052744
5EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.58111627
6* KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.30869068
7FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.19297981
8* EST1_17652178_ChIP-ChIP_JURKAT_Human3.15180450
9MYC_19079543_ChIP-ChIP_MESCs_Mouse3.00903292
10* GABP_17652178_ChIP-ChIP_JURKAT_Human2.94576230
11MYC_19030024_ChIP-ChIP_MESCs_Mouse2.86772305
12* JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.85872274
13MYC_18358816_ChIP-ChIP_MESCs_Mouse2.84399520
14* ETS1_20019798_ChIP-Seq_JURKAT_Human2.81508550
15CREB1_15753290_ChIP-ChIP_HEK293T_Human2.61251084
16HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.60194078
17CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.39739647
18NELFA_20434984_ChIP-Seq_ESCs_Mouse2.39387865
19MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.38146324
20* XRN2_22483619_ChIP-Seq_HELA_Human2.37569927
21NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.35494577
22* VDR_23849224_ChIP-Seq_CD4+_Human2.28127820
23ELF1_17652178_ChIP-ChIP_JURKAT_Human2.22189124
24MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.05281912
25* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.03193202
26* FOXP3_21729870_ChIP-Seq_TREG_Human2.02630919
27E2F1_21310950_ChIP-Seq_MCF-7_Human2.01322244
28AR_21909140_ChIP-Seq_LNCAP_Human1.99708448
29* DCP1A_22483619_ChIP-Seq_HELA_Human1.98375971
30THAP11_20581084_ChIP-Seq_MESCs_Mouse1.92410238
31* TTF2_22483619_ChIP-Seq_HELA_Human1.90718482
32EGR1_19374776_ChIP-ChIP_THP-1_Human1.88659828
33* GABP_19822575_ChIP-Seq_HepG2_Human1.85574506
34* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.84899210
35MYCN_18555785_ChIP-Seq_MESCs_Mouse1.83967799
36SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.83640686
37* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.78136906
38ELK1_19687146_ChIP-ChIP_HELA_Human1.77752058
39POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.76141421
40* KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.75730950
41PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.74155341
42NANOG_18555785_ChIP-Seq_MESCs_Mouse1.68428543
43E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.67869320
44YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.67575530
45FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.64838037
46* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.60164732
47CIITA_25753668_ChIP-Seq_RAJI_Human1.60139682
48YY1_21170310_ChIP-Seq_MESCs_Mouse1.58670754
49ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.58211977
50HOXB4_20404135_ChIP-ChIP_EML_Mouse1.56688224
51* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.53123296
52MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.52241431
53MYC_22102868_ChIP-Seq_BL_Human1.47360854
54TP63_19390658_ChIP-ChIP_HaCaT_Human1.46086640
55CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.45640359
56SRF_21415370_ChIP-Seq_HL-1_Mouse1.43192437
57CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.38212560
58CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.37852193
59* KDM5A_27292631_Chip-Seq_BREAST_Human1.37159774
60ERG_20887958_ChIP-Seq_HPC-7_Mouse1.32271869
61* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.31495108
62* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.31294702
63POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.26192369
64ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.24784893
65PADI4_21655091_ChIP-ChIP_MCF-7_Human1.24006324
66PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.18758056
67SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.16579495
68SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.16285994
69SOX2_18555785_ChIP-Seq_MESCs_Mouse1.16194152
70PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.14175552
71NOTCH1_21737748_ChIP-Seq_TLL_Human1.13249443
72* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.12980746
73POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.12487004
74KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.11894930
75KLF4_18555785_ChIP-Seq_MESCs_Mouse1.10469444
76TFEB_21752829_ChIP-Seq_HELA_Human1.10306480
77STAT3_1855785_ChIP-Seq_MESCs_Mouse1.08662792
78DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.04107496
79HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.03889970
80* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.01790282
81CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.00248518
82MYC_18940864_ChIP-ChIP_HL60_Human0.99428064
83RBPJ_22232070_ChIP-Seq_NCS_Mouse0.98155847
84GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.96691282
85SPI1_23547873_ChIP-Seq_NB4_Human0.95626186
86BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.94245829
87CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.93054764
88CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.92019455
89CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.91769690
90HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.91693704
91* ELK1_22589737_ChIP-Seq_MCF10A_Human0.90684744
92VDR_21846776_ChIP-Seq_THP-1_Human0.90536596
93SOX17_20123909_ChIP-Seq_XEN_Mouse0.90175224
94NANOG_16153702_ChIP-ChIP_HESCs_Human0.88624080
95KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.87286036
96NANOG_21062744_ChIP-ChIP_HESCs_Human0.84463700
97CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.84072938
98CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.83671704
99HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.79754659
100SALL1_21062744_ChIP-ChIP_HESCs_Human0.79631576
101SOX2_16153702_ChIP-ChIP_HESCs_Human0.79371006
102TCF3_18692474_ChIP-Seq_MEFs_Mouse0.77316619
103DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.76174328
104TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.73824569
105ESR1_15608294_ChIP-ChIP_MCF-7_Human0.71957016
106OCT4_18692474_ChIP-Seq_MEFs_Mouse0.71461704
107SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.70982699
108ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.70256377
109TBX5_21415370_ChIP-Seq_HL-1_Mouse0.65554004
110TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.65447571
111SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.64667121

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.19934221
2MP0010094_abnormal_chromosome_stability4.84115738
3MP0008057_abnormal_DNA_replication4.46834681
4MP0003111_abnormal_nucleus_morphology4.28289951
5MP0004957_abnormal_blastocyst_morpholog4.20094919
6MP0003077_abnormal_cell_cycle4.01754882
7MP0008058_abnormal_DNA_repair3.56019341
8MP0008007_abnormal_cellular_replicative2.89591005
9MP0008932_abnormal_embryonic_tissue2.68216247
10MP0003123_paternal_imprinting2.62585308
11MP0008877_abnormal_DNA_methylation2.36967903
12MP0009697_abnormal_copulation2.34395197
13MP0002396_abnormal_hematopoietic_system2.26374928
14MP0001730_embryonic_growth_arrest2.20653903
15MP0003786_premature_aging2.20184941
16MP0000350_abnormal_cell_proliferation2.16685406
17MP0006035_abnormal_mitochondrial_morpho2.03700138
18MP0010352_gastrointestinal_tract_polyps1.81736441
19MP0010307_abnormal_tumor_latency1.79284552
20MP0000490_abnormal_crypts_of1.77936171
21MP0003121_genomic_imprinting1.73017750
22MP0004808_abnormal_hematopoietic_stem1.63982658
23MP0001697_abnormal_embryo_size1.63402897
24MP0001672_abnormal_embryogenesis/_devel1.63247544
25MP0005380_embryogenesis_phenotype1.63247544
26MP0010030_abnormal_orbit_morphology1.63215184
27MP0006036_abnormal_mitochondrial_physio1.60997816
28MP0002080_prenatal_lethality1.48823181
29MP0002085_abnormal_embryonic_tissue1.47090091
30MP0000313_abnormal_cell_death1.46371503
31MP0003984_embryonic_growth_retardation1.45619436
32MP0006292_abnormal_olfactory_placode1.43477912
33MP0002088_abnormal_embryonic_growth/wei1.42582770
34MP0002019_abnormal_tumor_incidence1.40537085
35MP0000537_abnormal_urethra_morphology1.40293890
36MP0003890_abnormal_embryonic-extraembry1.40084982
37MP0003718_maternal_effect1.38711861
38MP0002084_abnormal_developmental_patter1.36357240
39MP0003567_abnormal_fetal_cardiomyocyte1.32759401
40MP0009333_abnormal_splenocyte_physiolog1.32338172
41MP0004197_abnormal_fetal_growth/weight/1.30159981
42MP0003763_abnormal_thymus_physiology1.27441458
43MP0002086_abnormal_extraembryonic_tissu1.26652246
44MP0002210_abnormal_sex_determination1.24198839
45MP0001293_anophthalmia1.23791590
46MP0000703_abnormal_thymus_morphology1.19760725
47MP0005397_hematopoietic_system_phenotyp1.16848433
48MP0001545_abnormal_hematopoietic_system1.16848433
49MP0002398_abnormal_bone_marrow1.13601070
50MP0003806_abnormal_nucleotide_metabolis1.10167744
51MP0003315_abnormal_perineum_morphology1.09857092
52MP0001145_abnormal_male_reproductive1.07717410
53MP0004133_heterotaxia1.06589783
54MP0002722_abnormal_immune_system1.05424903
55MP0006072_abnormal_retinal_apoptosis1.01040994
56MP0001661_extended_life_span0.99354709
57MP0000689_abnormal_spleen_morphology0.99098599
58MP0005076_abnormal_cell_differentiation0.96261060
59MP0001929_abnormal_gametogenesis0.95159631
60MP0003119_abnormal_digestive_system0.93695066
61MP0000653_abnormal_sex_gland0.92183520
62MP0002938_white_spotting0.90654891
63MP0000372_irregular_coat_pigmentation0.89180535
64MP0002429_abnormal_blood_cell0.89106490
65MP0000358_abnormal_cell_content/0.89017383
66MP0006054_spinal_hemorrhage0.88483450
67MP0002160_abnormal_reproductive_system0.87530195
68MP0001529_abnormal_vocalization0.86798492
69MP0005395_other_phenotype0.84381732
70MP0002132_abnormal_respiratory_system0.83356587
71MP0000858_altered_metastatic_potential0.82130832
72MP0001119_abnormal_female_reproductive0.80903798
73MP0003699_abnormal_female_reproductive0.80473413
74MP0005384_cellular_phenotype0.79459433
75MP0009278_abnormal_bone_marrow0.79087410
76MP0002111_abnormal_tail_morphology0.78257040
77MP0001727_abnormal_embryo_implantation0.77226088
78MP0005499_abnormal_olfactory_system0.76938333
79MP0005394_taste/olfaction_phenotype0.76938333
80MP0000716_abnormal_immune_system0.75559033
81MP0002697_abnormal_eye_size0.74434316
82MP0003186_abnormal_redox_activity0.74341448
83MP0002102_abnormal_ear_morphology0.73607647
84MP0004147_increased_porphyrin_level0.73532422
85MP0002161_abnormal_fertility/fecundity0.73179344
86MP0005389_reproductive_system_phenotype0.72939020
87MP0009703_decreased_birth_body0.72869904
88MP0003937_abnormal_limbs/digits/tail_de0.72534825
89MP0005075_abnormal_melanosome_morpholog0.72486056
90MP0003941_abnormal_skin_development0.72391336
91MP0003950_abnormal_plasma_membrane0.70050348
92MP0005621_abnormal_cell_physiology0.69575999
93MP0008789_abnormal_olfactory_epithelium0.68389561
94MP0003698_abnormal_male_reproductive0.67880354
95MP0004233_abnormal_muscle_weight0.67394563
96MP0000049_abnormal_middle_ear0.67226073
97MP0009053_abnormal_anal_canal0.66927294
98MP0000465_gastrointestinal_hemorrhage0.66814518
99MP0003943_abnormal_hepatobiliary_system0.65509430
100MP0005501_abnormal_skin_physiology0.65200163
101MP0001346_abnormal_lacrimal_gland0.65189619
102MP0002095_abnormal_skin_pigmentation0.64977539
103MP0002877_abnormal_melanocyte_morpholog0.64527527
104MP0009379_abnormal_foot_pigmentation0.63898936
105MP0002653_abnormal_ependyma_morphology0.63345355
106MP0001286_abnormal_eye_development0.63294592
107MP0005023_abnormal_wound_healing0.63069150
108MP0001835_abnormal_antigen_presentation0.62396061
109MP0008995_early_reproductive_senescence0.61847533
110MP0001881_abnormal_mammary_gland0.61800035
111MP0009672_abnormal_birth_weight0.61767955
112MP0005174_abnormal_tail_pigmentation0.61255564
113MP0001800_abnormal_humoral_immune0.60159404
114MP0000428_abnormal_craniofacial_morphol0.59698039
115MP0002075_abnormal_coat/hair_pigmentati0.59657372
116MP0002420_abnormal_adaptive_immunity0.59113195
117MP0002234_abnormal_pharynx_morphology0.58820241
118MP0001915_intracranial_hemorrhage0.58509884
119MP0002233_abnormal_nose_morphology0.58141422
120MP0000678_abnormal_parathyroid_gland0.58017899
121MP0001819_abnormal_immune_cell0.57960502
122MP0001853_heart_inflammation0.57018770
123MP0000477_abnormal_intestine_morphology0.56228722
124MP0002452_abnormal_antigen_presenting0.56037106
125MP0008770_decreased_survivor_rate0.55298968
126MP0003221_abnormal_cardiomyocyte_apopto0.55122318
127MP0005408_hypopigmentation0.55005506
128MP0000647_abnormal_sebaceous_gland0.53329153
129MP0003861_abnormal_nervous_system0.50958593
130MP0002092_abnormal_eye_morphology0.50729264
131MP0001764_abnormal_homeostasis0.48897858
132MP0005391_vision/eye_phenotype0.48782052
133MP0003646_muscle_fatigue0.47067238
134MP0002269_muscular_atrophy0.44551395
135MP0003656_abnormal_erythrocyte_physiolo0.44005946

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)4.77798689
2Reticulocytopenia (HP:0001896)4.58890272
3Abnormality of cells of the erythroid lineage (HP:0012130)3.83722049
4Chromsome breakage (HP:0040012)3.79854107
5Chromosomal breakage induced by crosslinking agents (HP:0003221)3.68462509
6Breast hypoplasia (HP:0003187)3.59380289
7Abnormal number of erythroid precursors (HP:0012131)3.59346643
8Selective tooth agenesis (HP:0001592)3.54148872
9Colon cancer (HP:0003003)3.48786849
10Patellar aplasia (HP:0006443)3.47400096
11Increased serum pyruvate (HP:0003542)3.41594990
12Microvesicular hepatic steatosis (HP:0001414)3.39974125
13Abnormality of glycolysis (HP:0004366)3.32739874
14Meckel diverticulum (HP:0002245)3.30073311
15Multiple enchondromatosis (HP:0005701)3.28238759
16Abnormality of chromosome stability (HP:0003220)3.27961193
17Aplasia/Hypoplasia of the patella (HP:0006498)3.26384397
18Abnormality of the ileum (HP:0001549)3.21201866
19Abnormality of the preputium (HP:0100587)3.20887685
20Oral leukoplakia (HP:0002745)3.08537681
21Aplasia/Hypoplasia of the uvula (HP:0010293)3.07391909
22Medulloblastoma (HP:0002885)3.05964266
23Abnormality of the anterior horn cell (HP:0006802)3.05137541
24Degeneration of anterior horn cells (HP:0002398)3.05137541
25Rough bone trabeculation (HP:0100670)2.89390631
26Acute necrotizing encephalopathy (HP:0006965)2.89005058
2711 pairs of ribs (HP:0000878)2.87784139
28Ependymoma (HP:0002888)2.85168080
29Absent thumb (HP:0009777)2.84673171
30Carpal bone hypoplasia (HP:0001498)2.81902192
31Myelodysplasia (HP:0002863)2.80772521
32Increased hepatocellular lipid droplets (HP:0006565)2.77363485
33Agnosia (HP:0010524)2.76998597
34Aplastic anemia (HP:0001915)2.76946257
35Absent radius (HP:0003974)2.76526514
36Acute encephalopathy (HP:0006846)2.73610438
37Macrocytic anemia (HP:0001972)2.73593268
38Pallor (HP:0000980)2.73172628
39Abnormal mitochondria in muscle tissue (HP:0008316)2.72449897
40Increased CSF lactate (HP:0002490)2.68680042
41Small intestinal stenosis (HP:0012848)2.65452128
42Duodenal stenosis (HP:0100867)2.65452128
43Impulsivity (HP:0100710)2.54049086
44Absent forearm bone (HP:0003953)2.53653001
45Aplasia involving forearm bones (HP:0009822)2.53653001
46Cortical dysplasia (HP:0002539)2.53252543
47Abnormal gallbladder physiology (HP:0012438)2.53145749
48Cholecystitis (HP:0001082)2.53145749
49Premature graying of hair (HP:0002216)2.52837035
50Bone marrow hypocellularity (HP:0005528)2.51891325
51Abnormal number of incisors (HP:0011064)2.50678432
52Increased serum lactate (HP:0002151)2.50665435
53Supernumerary spleens (HP:0009799)2.50147850
54Abnormality of the labia minora (HP:0012880)2.47259119
55Lipid accumulation in hepatocytes (HP:0006561)2.45236724
56Neoplasm of the pancreas (HP:0002894)2.43733548
57Cerebral hypomyelination (HP:0006808)2.41399643
58Hepatocellular necrosis (HP:0001404)2.38920857
59Mitochondrial inheritance (HP:0001427)2.37926592
60Sloping forehead (HP:0000340)2.34545398
61Abnormal lung lobation (HP:0002101)2.34381760
62Microretrognathia (HP:0000308)2.28335340
63Basal cell carcinoma (HP:0002671)2.28321221
64Rhabdomyosarcoma (HP:0002859)2.28206507
65Abnormality of the pons (HP:0007361)2.28188666
66Cerebral edema (HP:0002181)2.27126260
67Triphalangeal thumb (HP:0001199)2.26199626
68Cellular immunodeficiency (HP:0005374)2.25291748
69Progressive muscle weakness (HP:0003323)2.24970736
70Atresia of the external auditory canal (HP:0000413)2.23445262
71Hypoplasia of the capital femoral epiphysis (HP:0003090)2.22867140
72Tracheoesophageal fistula (HP:0002575)2.22145710
73Abnormality of the duodenum (HP:0002246)2.19236121
74Progressive macrocephaly (HP:0004481)2.19147150
75Aplasia/Hypoplasia of the sacrum (HP:0008517)2.16109254
76Abnormality of methionine metabolism (HP:0010901)2.15693597
77Trismus (HP:0000211)2.15604351
78Thrombocytosis (HP:0001894)2.15027987
79Cleft eyelid (HP:0000625)2.14506374
80Duplicated collecting system (HP:0000081)2.14386227
81Hepatic necrosis (HP:0002605)2.10888044
82Postnatal microcephaly (HP:0005484)2.10620813
83Lymphoma (HP:0002665)2.09774703
84Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.09538536
85Proximal placement of thumb (HP:0009623)2.08327426
86Ectopic kidney (HP:0000086)2.08112456
87Abnormal protein glycosylation (HP:0012346)2.06170178
88Abnormal glycosylation (HP:0012345)2.06170178
89Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.06170178
90Abnormal protein N-linked glycosylation (HP:0012347)2.06170178
91Lactic acidosis (HP:0003128)2.05961006
92Progressive external ophthalmoplegia (HP:0000590)2.05461766
93Volvulus (HP:0002580)2.04950756
94Horseshoe kidney (HP:0000085)2.04246861
95Asplenia (HP:0001746)2.03981797
96Abnormality of cochlea (HP:0000375)2.03640552
97Abnormal trabecular bone morphology (HP:0100671)2.02790296
98Deviation of the thumb (HP:0009603)2.00845602
99Abnormality of the carotid arteries (HP:0005344)2.00211714
100Amaurosis fugax (HP:0100576)1.99228712
101Increased nuchal translucency (HP:0010880)1.98875910
102Hypoplasia of the pons (HP:0012110)1.98777848
103Abnormality of the renal collecting system (HP:0004742)1.97344138
104Exercise intolerance (HP:0003546)1.97343811
105IgM deficiency (HP:0002850)1.96412801
106Premature ovarian failure (HP:0008209)1.95550499
107Squamous cell carcinoma (HP:0002860)1.94349979
108Missing ribs (HP:0000921)1.92858822
109Abnormality of alanine metabolism (HP:0010916)1.92704344
110Hyperalaninemia (HP:0003348)1.92704344
111Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.92704344
112Pancytopenia (HP:0001876)1.91172454
113Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.89360365
114Decreased activity of mitochondrial respiratory chain (HP:0008972)1.89360365
115Irregular epiphyses (HP:0010582)1.89010674
116Short thumb (HP:0009778)1.88997055
117Respiratory difficulties (HP:0002880)1.88774661
118Aplasia/Hypoplasia of the spleen (HP:0010451)1.88210602
119Type I transferrin isoform profile (HP:0003642)1.87583850
120Choanal atresia (HP:0000453)1.87491976
121Secondary amenorrhea (HP:0000869)1.85812639
122Clubbing of toes (HP:0100760)1.84928755
123Nephroblastoma (Wilms tumor) (HP:0002667)1.84769143
124CNS hypomyelination (HP:0003429)1.80793608
125Abdominal situs inversus (HP:0003363)1.80108169
126Abnormality of abdominal situs (HP:0011620)1.80108169
127Increased intramyocellular lipid droplets (HP:0012240)1.79431661
128Prominent nose (HP:0000448)1.78792241
129Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.77404170
130Absent epiphyses (HP:0010577)1.77404170
131Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.76693384
132Cafe-au-lait spot (HP:0000957)1.75580054
133Glossoptosis (HP:0000162)1.75458068
134Spastic diplegia (HP:0001264)1.75307767
135Abnormality of DNA repair (HP:0003254)1.74843048
136Hypoplasia of the radius (HP:0002984)1.74356025
137Facial cleft (HP:0002006)1.74226894
138Megaloblastic anemia (HP:0001889)1.74154884
139Aplasia/Hypoplasia of the sternum (HP:0006714)1.73710942
140Slender long bone (HP:0003100)1.73049631
141Embryonal renal neoplasm (HP:0011794)1.70859876
142Glioma (HP:0009733)1.70616726
143Muscle fiber atrophy (HP:0100295)1.70218383
144Neoplasm of the colon (HP:0100273)1.69768471

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.60697050
2CDC74.40540846
3WEE14.20541213
4VRK23.13197680
5EIF2AK13.04257753
6PLK42.74204155
7SRPK12.65698085
8TSSK62.50499118
9NEK22.45196720
10ACVR1B2.29505899
11PASK2.29295869
12TTK2.21694105
13MKNK12.21399226
14STK162.14047565
15VRK12.10824339
16PLK12.05438314
17NME21.93473905
18EIF2AK31.87954756
19TLK11.87314310
20ATR1.86256633
21BRSK21.85477407
22NEK11.84027924
23TGFBR11.81560349
24TRIM281.75709397
25AURKB1.73756649
26CDK71.72605416
27RPS6KB21.70079710
28PLK31.63962239
29DYRK31.53939656
30CCNB11.43980213
31PDK21.40394863
32MKNK21.39170874
33TESK21.39119770
34CHEK21.37514084
35RPS6KA41.27704046
36STK101.25216275
37CHEK11.23557919
38PBK1.20169156
39AURKA1.19282389
40MAP3K81.17727647
41EEF2K1.16507857
42BRSK11.15524363
43TAF11.15206745
44PAK41.12967232
45NUAK11.12448715
46CDK41.11745601
47CDK121.11057818
48ZAK1.04122950
49MAP4K11.03788634
50STK41.00454713
51EIF2AK21.00277588
52CDK80.98142506
53SCYL20.94399421
54BCKDK0.92160514
55ATM0.89095611
56PIM10.85340709
57EPHA20.83990702
58CDK20.83104041
59PIM20.78706275
60FLT30.75924901
61CSNK2A10.75582197
62CSNK2A20.74654536
63SMG10.70910248
64MAP3K100.69118705
65YES10.68134722
66MAPKAPK50.67702431
67BRD40.66929312
68TESK10.66640963
69BMPR1B0.65653507
70CDK10.64705606
71CSNK1G30.64627212
72CSNK1G10.63890513
73CLK10.62781808
74MELK0.61912872
75PNCK0.61534343
76CDK90.58701894
77PAK10.57679110
78RPS6KA50.57656410
79LRRK20.55156683
80MST40.53877689
81DYRK20.52099935
82KDR0.51893202
83CDK60.50631142
84BTK0.50041714
85CDK190.49898888
86MAP3K110.49525121
87TXK0.48382195
88BCR0.46250686
89CSNK1A1L0.46151936
90ALK0.44320316
91WNK30.43625406
92ERBB40.43068227
93TNIK0.42480285
94RAF10.41372042
95KIT0.41038363
96MAP2K30.39202078
97PLK20.37532164
98STK30.36880442
99CSF1R0.36684330
100AKT20.36548159
101WNK40.35729595
102BRAF0.35630558
103TAOK20.33899544
104CSNK1G20.33734919
105ZAP700.32075752
106IRAK40.31952541
107TIE10.31456241
108PRKDC0.30611785
109LYN0.29724191
110PRKCI0.29209226
111CDK11A0.28595120
112CDK180.28248400
113TEC0.27772850
114CSNK1E0.27402831
115FGFR10.26990016
116JAK30.26099837
117DAPK10.25426228
118CDK150.25294837
119NEK60.24177694
120CDK140.24061348
121STK38L0.23912818
122NME10.23723270
123MTOR0.23056791
124LIMK10.20443000
125ERBB30.20169570
126MAPKAPK30.19983942
127MAPK140.19978525
128CHUK0.19668049

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030305.09891889
2Mismatch repair_Homo sapiens_hsa034304.45317776
3Ribosome_Homo sapiens_hsa030103.58418022
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.56514485
5* Spliceosome_Homo sapiens_hsa030403.45660463
6Proteasome_Homo sapiens_hsa030503.40761635
7Base excision repair_Homo sapiens_hsa034103.24660195
8RNA polymerase_Homo sapiens_hsa030203.12850858
9Homologous recombination_Homo sapiens_hsa034403.12393149
10RNA transport_Homo sapiens_hsa030133.05776688
11Nucleotide excision repair_Homo sapiens_hsa034202.95925059
12Cell cycle_Homo sapiens_hsa041102.70396880
13Pyrimidine metabolism_Homo sapiens_hsa002402.45089275
14One carbon pool by folate_Homo sapiens_hsa006702.44564451
15Fanconi anemia pathway_Homo sapiens_hsa034602.36520016
16Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.29872345
17Non-homologous end-joining_Homo sapiens_hsa034502.22442517
18RNA degradation_Homo sapiens_hsa030181.96253178
19Basal transcription factors_Homo sapiens_hsa030221.94958494
20Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.82555603
21mRNA surveillance pathway_Homo sapiens_hsa030151.80459693
22p53 signaling pathway_Homo sapiens_hsa041151.56249461
232-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.42467347
24Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.41676846
25Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.31706036
26Purine metabolism_Homo sapiens_hsa002301.30131185
27Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.29493252
28Pyruvate metabolism_Homo sapiens_hsa006201.28249641
29Epstein-Barr virus infection_Homo sapiens_hsa051691.25276155
30Systemic lupus erythematosus_Homo sapiens_hsa053221.20479974
31Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.16770385
32Protein export_Homo sapiens_hsa030601.08680984
33Propanoate metabolism_Homo sapiens_hsa006401.05628659
34Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.04989735
35Herpes simplex infection_Homo sapiens_hsa051681.02131984
36Fatty acid elongation_Homo sapiens_hsa000621.00248918
37Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.95828293
38Antigen processing and presentation_Homo sapiens_hsa046120.95405445
39Viral carcinogenesis_Homo sapiens_hsa052030.94472826
40Oocyte meiosis_Homo sapiens_hsa041140.86645174
41Steroid biosynthesis_Homo sapiens_hsa001000.86434243
42Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.80566998
43HTLV-I infection_Homo sapiens_hsa051660.75761365
44Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.75500249
45Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.74371911
46Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.73377447
47Legionellosis_Homo sapiens_hsa051340.72019065
48Pentose phosphate pathway_Homo sapiens_hsa000300.70262920
49Primary immunodeficiency_Homo sapiens_hsa053400.68411644
50Folate biosynthesis_Homo sapiens_hsa007900.68349486
51Alzheimers disease_Homo sapiens_hsa050100.64849985
52Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.63880792
53Cysteine and methionine metabolism_Homo sapiens_hsa002700.61914569
54Drug metabolism - other enzymes_Homo sapiens_hsa009830.60444465
55Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.57542346
56Transcriptional misregulation in cancer_Homo sapiens_hsa052020.56764748
57Huntingtons disease_Homo sapiens_hsa050160.55936277
58Biosynthesis of amino acids_Homo sapiens_hsa012300.55827933
59Measles_Homo sapiens_hsa051620.52164270
60Selenocompound metabolism_Homo sapiens_hsa004500.51939354
61MicroRNAs in cancer_Homo sapiens_hsa052060.51065663
62Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.49778005
63Cyanoamino acid metabolism_Homo sapiens_hsa004600.49483053
64N-Glycan biosynthesis_Homo sapiens_hsa005100.49034766
65Thyroid cancer_Homo sapiens_hsa052160.48290901
66Shigellosis_Homo sapiens_hsa051310.48199877
67Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.47191363
68NF-kappa B signaling pathway_Homo sapiens_hsa040640.46684191
69Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.45839472
70Vitamin B6 metabolism_Homo sapiens_hsa007500.44093793
71Alcoholism_Homo sapiens_hsa050340.42157505
72Glutathione metabolism_Homo sapiens_hsa004800.42020152
73Apoptosis_Homo sapiens_hsa042100.41574698
74Basal cell carcinoma_Homo sapiens_hsa052170.40687732
75Small cell lung cancer_Homo sapiens_hsa052220.39954609
76Lysine degradation_Homo sapiens_hsa003100.39504554
77Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.39185010
78TGF-beta signaling pathway_Homo sapiens_hsa043500.38266376
79Hepatitis B_Homo sapiens_hsa051610.38031394
80Colorectal cancer_Homo sapiens_hsa052100.36490296
81Parkinsons disease_Homo sapiens_hsa050120.36221205
82Hippo signaling pathway_Homo sapiens_hsa043900.36172079
83Notch signaling pathway_Homo sapiens_hsa043300.35497245
84Hematopoietic cell lineage_Homo sapiens_hsa046400.35076415
85Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.34139496
86Fatty acid metabolism_Homo sapiens_hsa012120.33924232
87Influenza A_Homo sapiens_hsa051640.33729188
88Intestinal immune network for IgA production_Homo sapiens_hsa046720.33422138
89Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.33084491
90Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.31998763
91Allograft rejection_Homo sapiens_hsa053300.31757788
92NOD-like receptor signaling pathway_Homo sapiens_hsa046210.31290962
93RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.30777914
94Sulfur relay system_Homo sapiens_hsa041220.28728851
95Arginine and proline metabolism_Homo sapiens_hsa003300.28023356
96Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.26570479
97Graft-versus-host disease_Homo sapiens_hsa053320.23539811
98Pathways in cancer_Homo sapiens_hsa052000.23245359
99Viral myocarditis_Homo sapiens_hsa054160.21906508
100Fructose and mannose metabolism_Homo sapiens_hsa000510.21165547
101Central carbon metabolism in cancer_Homo sapiens_hsa052300.20496389
102Oxidative phosphorylation_Homo sapiens_hsa001900.18723728
103HIF-1 signaling pathway_Homo sapiens_hsa040660.18325415
104Hedgehog signaling pathway_Homo sapiens_hsa043400.18297578
105Autoimmune thyroid disease_Homo sapiens_hsa053200.17721890
106Carbon metabolism_Homo sapiens_hsa012000.17423777
107Peroxisome_Homo sapiens_hsa041460.16480148
108Arachidonic acid metabolism_Homo sapiens_hsa005900.16379184
109Asthma_Homo sapiens_hsa053100.15544141
110Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.15364056
111Sulfur metabolism_Homo sapiens_hsa009200.15251347
112Metabolic pathways_Homo sapiens_hsa011000.14789316
113Regulation of autophagy_Homo sapiens_hsa041400.14158488
114Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.14054293
115Leishmaniasis_Homo sapiens_hsa051400.13192329
116Chronic myeloid leukemia_Homo sapiens_hsa052200.12781576
117Galactose metabolism_Homo sapiens_hsa000520.12430196
118Type I diabetes mellitus_Homo sapiens_hsa049400.12096647
119Bladder cancer_Homo sapiens_hsa052190.10360443
120Renin-angiotensin system_Homo sapiens_hsa046140.10029135
121Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.09952104
122Adherens junction_Homo sapiens_hsa045200.09734035
123Wnt signaling pathway_Homo sapiens_hsa043100.09641196
124Acute myeloid leukemia_Homo sapiens_hsa052210.09581524
125Butanoate metabolism_Homo sapiens_hsa006500.06824354
126Arginine biosynthesis_Homo sapiens_hsa002200.06038228
127Pentose and glucuronate interconversions_Homo sapiens_hsa000400.03697321
128Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.00438499
129Cardiac muscle contraction_Homo sapiens_hsa04260-0.0044078

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