Rank | Gene Set | Z-score |
---|---|---|
1 | positive regulation of gamma-delta T cell activation (GO:0046645) | 4.96686593 |
2 | tolerance induction (GO:0002507) | 4.67968944 |
3 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 4.40287152 |
4 | behavioral response to nicotine (GO:0035095) | 4.33115039 |
5 | histone H3-K4 trimethylation (GO:0080182) | 4.23419935 |
6 | fucose catabolic process (GO:0019317) | 4.00573770 |
7 | L-fucose metabolic process (GO:0042354) | 4.00573770 |
8 | L-fucose catabolic process (GO:0042355) | 4.00573770 |
9 | activated T cell proliferation (GO:0050798) | 3.98386526 |
10 | negative regulation of cell killing (GO:0031342) | 3.95946663 |
11 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 3.95946663 |
12 | sulfation (GO:0051923) | 3.93138136 |
13 | cellular response to exogenous dsRNA (GO:0071360) | 3.86720862 |
14 | G-protein coupled receptor internalization (GO:0002031) | 3.74624438 |
15 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.57431379 |
16 | negative regulation of granulocyte differentiation (GO:0030853) | 3.54469545 |
17 | histone H3-K36 demethylation (GO:0070544) | 3.53704562 |
18 | positive regulation of defense response to virus by host (GO:0002230) | 3.53092449 |
19 | cellular response to ATP (GO:0071318) | 3.49941131 |
20 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 3.47078068 |
21 | regulation of gamma-delta T cell activation (GO:0046643) | 3.39935811 |
22 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 3.38422593 |
23 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 3.37046299 |
24 | regulation of translation, ncRNA-mediated (GO:0045974) | 3.37046299 |
25 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 3.37046299 |
26 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.33253138 |
27 | modulation by virus of host process (GO:0019054) | 3.33074388 |
28 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.28366470 |
29 | regulation of histone H3-K27 methylation (GO:0061085) | 3.24314473 |
30 | superoxide anion generation (GO:0042554) | 3.21541896 |
31 | peptidyl-lysine trimethylation (GO:0018023) | 3.20252959 |
32 | mature B cell differentiation (GO:0002335) | 3.19881321 |
33 | histone H3-K4 methylation (GO:0051568) | 3.14591979 |
34 | positive regulation of granulocyte differentiation (GO:0030854) | 3.09694203 |
35 | positive regulation of CREB transcription factor activity (GO:0032793) | 3.09660424 |
36 | detection of chemical stimulus involved in sensory perception of bitter taste (GO:0001580) | 3.07938088 |
37 | modulation by symbiont of host cellular process (GO:0044068) | 3.06327211 |
38 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 3.06233438 |
39 | regulation of alpha-beta T cell proliferation (GO:0046640) | 3.02204147 |
40 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 3.01611875 |
41 | cellular response to interleukin-15 (GO:0071350) | 3.01217089 |
42 | germinal center formation (GO:0002467) | 3.00694218 |
43 | negative regulation of T cell mediated immunity (GO:0002710) | 2.98683723 |
44 | positive thymic T cell selection (GO:0045059) | 2.97969235 |
45 | kynurenine metabolic process (GO:0070189) | 2.95603717 |
46 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla | 2.95186969 |
47 | positive regulation of humoral immune response (GO:0002922) | 2.93214085 |
48 | regulation of T cell mediated cytotoxicity (GO:0001914) | 2.92992131 |
49 | detection of bacterium (GO:0016045) | 2.92478564 |
50 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 2.92106370 |
51 | DNA deamination (GO:0045006) | 2.91697074 |
52 | histone H3-K9 demethylation (GO:0033169) | 2.89897542 |
53 | indolalkylamine metabolic process (GO:0006586) | 2.89539000 |
54 | regulation of gamma-delta T cell differentiation (GO:0045586) | 2.89280204 |
55 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 2.89268780 |
56 | positive regulation of antigen processing and presentation (GO:0002579) | 2.87313530 |
57 | regulation of regulatory T cell differentiation (GO:0045589) | 2.85013915 |
58 | detection of other organism (GO:0098543) | 2.83825514 |
59 | histone lysine demethylation (GO:0070076) | 2.81560681 |
60 | tryptophan metabolic process (GO:0006568) | 2.81466773 |
61 | positive regulation of cellular amide metabolic process (GO:0034250) | 2.76225936 |
62 | B cell receptor signaling pathway (GO:0050853) | 2.73729775 |
63 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.73236623 |
64 | regulation of memory T cell differentiation (GO:0043380) | 2.73008129 |
65 | mast cell activation involved in immune response (GO:0002279) | 2.72853262 |
66 | mast cell degranulation (GO:0043303) | 2.72853262 |
67 | regulation of granulocyte differentiation (GO:0030852) | 2.72704876 |
68 | detection of chemical stimulus involved in sensory perception of taste (GO:0050912) | 2.70814468 |
69 | mast cell activation (GO:0045576) | 2.70319948 |
70 | phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092) | 2.69551940 |
71 | B cell homeostasis (GO:0001782) | 2.67258402 |
72 | positive regulation of fatty acid beta-oxidation (GO:0032000) | 2.67131389 |
73 | amino sugar catabolic process (GO:0046348) | 2.66699949 |
74 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.66663884 |
75 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 2.66031219 |
76 | DNA damage response, signal transduction resulting in transcription (GO:0042772) | 2.65869269 |
77 | regulation of defense response to virus by host (GO:0050691) | 2.65251205 |
78 | regulation of MHC class I biosynthetic process (GO:0045343) | 2.65074056 |
79 | meiotic chromosome segregation (GO:0045132) | 2.64907113 |
80 | response to peptidoglycan (GO:0032494) | 2.64316488 |
81 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 2.63409009 |
82 | histone demethylation (GO:0016577) | 2.63121249 |
83 | alpha-beta T cell differentiation (GO:0046632) | 2.63041718 |
84 | response to interleukin-15 (GO:0070672) | 2.61617330 |
85 | cytidine deamination (GO:0009972) | 2.61102127 |
86 | cytidine metabolic process (GO:0046087) | 2.61102127 |
87 | cytidine catabolic process (GO:0006216) | 2.61102127 |
88 | regulation of isotype switching to IgG isotypes (GO:0048302) | 2.60442005 |
89 | positive regulation of calcium-mediated signaling (GO:0050850) | 2.59357734 |
90 | 3-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427) | 2.59045052 |
91 | purine ribonucleoside bisphosphate metabolic process (GO:0034035) | 2.59045052 |
92 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 2.58844845 |
93 | positive T cell selection (GO:0043368) | 2.57932233 |
94 | energy homeostasis (GO:0097009) | 2.57731598 |
95 | negative regulation of T-helper cell differentiation (GO:0045623) | 2.57722504 |
96 | negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371) | 2.57722504 |
97 | response to muramyl dipeptide (GO:0032495) | 2.55737598 |
98 | positive regulation of interleukin-1 beta secretion (GO:0050718) | 2.55509485 |
99 | purinergic nucleotide receptor signaling pathway (GO:0035590) | 2.55354184 |
100 | interferon-gamma secretion (GO:0072643) | 2.54808252 |
101 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 2.54082622 |
102 | regulation of antigen processing and presentation (GO:0002577) | 2.53753909 |
103 | positive regulation of fatty acid oxidation (GO:0046321) | 2.53731507 |
104 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 2.51911504 |
105 | leukocyte aggregation (GO:0070486) | 2.51396554 |
106 | NIK/NF-kappaB signaling (GO:0038061) | 2.51341246 |
107 | female gonad development (GO:0008585) | 2.51308507 |
108 | negative T cell selection (GO:0043383) | 2.50223049 |
109 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 2.50010826 |
110 | thymic T cell selection (GO:0045061) | 2.49724301 |
111 | negative thymic T cell selection (GO:0045060) | 2.49578457 |
112 | positive regulation of cholesterol efflux (GO:0010875) | 2.48883711 |
113 | detection of chemical stimulus involved in sensory perception (GO:0050907) | 2.48635058 |
114 | androgen biosynthetic process (GO:0006702) | 2.48350005 |
115 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 2.47899038 |
116 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 2.47738497 |
117 | positive regulation of T-helper 1 type immune response (GO:0002827) | 2.46902689 |
118 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 2.46507559 |
119 | regulation of natural killer cell mediated immunity (GO:0002715) | 2.46507559 |
120 | interkinetic nuclear migration (GO:0022027) | 2.45875788 |
121 | antigen receptor-mediated signaling pathway (GO:0050851) | 2.45789086 |
122 | interferon-gamma production (GO:0032609) | 2.45188099 |
123 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 2.44532499 |
124 | positive regulation of interferon-alpha production (GO:0032727) | 2.43932297 |
125 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 2.43904647 |
126 | regulation of syncytium formation by plasma membrane fusion (GO:0060142) | 2.43534205 |
127 | poly(A)+ mRNA export from nucleus (GO:0016973) | 2.42813016 |
128 | regulation of T cell receptor signaling pathway (GO:0050856) | 2.42615175 |
129 | regulation of T-helper 1 type immune response (GO:0002825) | 2.42539096 |
130 | positive regulation of interleukin-1 secretion (GO:0050716) | 2.42371107 |
131 | defense response to protozoan (GO:0042832) | 2.42110841 |
132 | NAD biosynthetic process (GO:0009435) | 2.42079103 |
133 | regulation of platelet aggregation (GO:0090330) | 2.41475877 |
134 | positive regulation of cAMP-mediated signaling (GO:0043950) | 2.41203098 |
135 | negative regulation of nitric oxide biosynthetic process (GO:0045019) | 2.40818621 |
136 | negative regulation of cAMP-mediated signaling (GO:0043951) | 2.40719288 |
137 | indole-containing compound catabolic process (GO:0042436) | 2.40675715 |
138 | indolalkylamine catabolic process (GO:0046218) | 2.40675715 |
139 | tryptophan catabolic process (GO:0006569) | 2.40675715 |
140 | Peyers patch development (GO:0048541) | 2.40541418 |
141 | mucosal-associated lymphoid tissue development (GO:0048537) | 2.40541418 |
142 | T cell selection (GO:0045058) | 2.40504090 |
143 | detection of molecule of bacterial origin (GO:0032490) | 2.40172566 |
144 | regulation of B cell differentiation (GO:0045577) | 2.40007594 |
145 | protein K48-linked deubiquitination (GO:0071108) | 2.39942204 |
146 | replicative senescence (GO:0090399) | 2.39735493 |
147 | regulation of interleukin-1 beta secretion (GO:0050706) | 2.37939335 |
148 | regulation of cell killing (GO:0031341) | 2.37573432 |
149 | regulation of interferon-alpha production (GO:0032647) | 2.37295589 |
150 | antigen processing and presentation of endogenous antigen (GO:0019883) | 2.34780507 |
151 | negative regulation of keratinocyte proliferation (GO:0010839) | 2.33915974 |
152 | oligosaccharide catabolic process (GO:0009313) | 2.33516699 |
153 | sulfate transmembrane transport (GO:1902358) | 2.30854723 |
154 | B cell differentiation (GO:0030183) | 2.29646866 |
155 | sulfate transport (GO:0008272) | 2.29395668 |
156 | positive regulation of B cell differentiation (GO:0045579) | 2.28368424 |
157 | left/right axis specification (GO:0070986) | 2.27844482 |
158 | DNA integration (GO:0015074) | 2.27790326 |
159 | mature B cell differentiation involved in immune response (GO:0002313) | 2.27624123 |
160 | histone H4-K12 acetylation (GO:0043983) | 2.26771797 |
161 | cellular biogenic amine catabolic process (GO:0042402) | 2.26009159 |
162 | amine catabolic process (GO:0009310) | 2.26009159 |
163 | detection of external biotic stimulus (GO:0098581) | 2.25161484 |
164 | response to host immune response (GO:0052572) | 2.24157468 |
165 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 2.24157468 |
166 | histone H3-K9 methylation (GO:0051567) | 2.23574697 |
167 | T cell migration (GO:0072678) | 2.22887992 |
168 | histone H3-K9 modification (GO:0061647) | 2.22656139 |
169 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 2.21695054 |
170 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 2.21695054 |
171 | modulation by symbiont of host immune response (GO:0052553) | 2.21695054 |
172 | positive regulation by symbiont of host defense response (GO:0052509) | 2.21695054 |
173 | modulation by symbiont of host defense response (GO:0052031) | 2.21695054 |
174 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 2.21695054 |
175 | regulation of germinal center formation (GO:0002634) | 2.21502399 |
Rank | Gene Set | Z-score |
---|---|---|
1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 3.13531876 |
2 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.84613759 |
3 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.65914127 |
4 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 2.55923735 |
5 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 2.55155990 |
6 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 2.51973848 |
7 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 2.50545026 |
8 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.44586541 |
9 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 2.37792543 |
10 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.35246609 |
11 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.34340779 |
12 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.23598998 |
13 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.20841894 |
14 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.18955194 |
15 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.09863625 |
16 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 2.08145218 |
17 | * SCL_19346495_ChIP-Seq_HPC-7_Human | 1.99800197 |
18 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.95775747 |
19 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.89527814 |
20 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.84979412 |
21 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.82931242 |
22 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.82728348 |
23 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.82574278 |
24 | * KAP1_22055183_ChIP-Seq_ESCs_Mouse | 1.81243650 |
25 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.80554886 |
26 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 1.77059843 |
27 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.76923535 |
28 | MAF_26560356_Chip-Seq_TH1_Human | 1.76714886 |
29 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.75878754 |
30 | UTX_26944678_Chip-Seq_JUKART_Human | 1.73624999 |
31 | NMYC_18555785_Chip-Seq_ESCs_Mouse | 1.71248182 |
32 | MAF_26560356_Chip-Seq_TH2_Human | 1.67562095 |
33 | * CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.65597968 |
34 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.65201253 |
35 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.64434725 |
36 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.64264319 |
37 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.62016970 |
38 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.61664521 |
39 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.61574651 |
40 | * OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.60801338 |
41 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.60676080 |
42 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 1.60279527 |
43 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.57358868 |
44 | GATA3_26560356_Chip-Seq_TH2_Human | 1.57073836 |
45 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.56780473 |
46 | MYC_22102868_ChIP-Seq_BL_Human | 1.56375781 |
47 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.55810026 |
48 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.55687400 |
49 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 1.54154094 |
50 | ESRRB_18555785_Chip-Seq_ESCs_Mouse | 1.53247237 |
51 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 1.52765737 |
52 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.52236001 |
53 | ZFX_18555785_Chip-Seq_ESCs_Mouse | 1.49357502 |
54 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.49254853 |
55 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.48761611 |
56 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.47254494 |
57 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.46569674 |
58 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.46377669 |
59 | PU1_27457419_Chip-Seq_LIVER_Mouse | 1.46198725 |
60 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 1.46071060 |
61 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.45724672 |
62 | P300_18555785_Chip-Seq_ESCs_Mouse | 1.45305793 |
63 | * SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.45134504 |
64 | CMYC_18555785_Chip-Seq_ESCs_Mouse | 1.44458905 |
65 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.44180788 |
66 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.42709924 |
67 | KLF4_18555785_Chip-Seq_ESCs_Mouse | 1.41615041 |
68 | CTCF_18555785_Chip-Seq_ESCs_Mouse | 1.40606800 |
69 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.40185996 |
70 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 1.39692668 |
71 | * CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.39293126 |
72 | ERA_21632823_ChIP-Seq_H3396_Human | 1.38235630 |
73 | SMAD1_18555785_Chip-Seq_ESCs_Mouse | 1.35190396 |
74 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.34379668 |
75 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.34037398 |
76 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.33985911 |
77 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.33746886 |
78 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.32809588 |
79 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.31685567 |
80 | * ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.30281207 |
81 | P68_20966046_ChIP-Seq_HELA_Human | 1.29107372 |
82 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.28187161 |
83 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.26357240 |
84 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.24687092 |
85 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.24186864 |
86 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.23239931 |
87 | VDR_22108803_ChIP-Seq_LS180_Human | 1.22785455 |
88 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.22489696 |
89 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.20689471 |
90 | P300_27268052_Chip-Seq_Bcells_Human | 1.20631368 |
91 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.18657441 |
92 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.17936830 |
93 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.17086074 |
94 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.16526478 |
95 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.16526478 |
96 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.16419621 |
97 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.16186633 |
98 | * EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.14886651 |
99 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.14311619 |
100 | PHF8_20622854_ChIP-Seq_HELA_Human | 1.12958370 |
101 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.10835042 |
102 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.10492612 |
103 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 1.09260054 |
104 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.09046958 |
105 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.08578904 |
106 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.08229954 |
107 | SMRT_27268052_Chip-Seq_Bcells_Human | 1.06365187 |
108 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.05648270 |
109 | GATA1_22025678_ChIP-Seq_K562_Human | 1.05343291 |
110 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.05180937 |
111 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.04354056 |
112 | * STAT1_17558387_ChIP-Seq_HELA_Human | 1.03245545 |
113 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.03078854 |
114 | MYB_26560356_Chip-Seq_TH1_Human | 1.02057894 |
115 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.01774509 |
116 | * GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.01126175 |
117 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.00718353 |
118 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.00174642 |
119 | TBL1_22424771_ChIP-Seq_293T_Human | 0.99657207 |
120 | OCT4_20526341_ChIP-Seq_ESCs_Human | 0.98999784 |
121 | * GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.98720490 |
122 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.98703688 |
123 | KDM2B_26808549_Chip-Seq_REH_Human | 0.98492237 |
124 | OCT4_19829295_ChIP-Seq_ESCs_Human | 0.98193160 |
125 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.97616437 |
126 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.96917605 |
127 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 0.96858186 |
128 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 0.96588275 |
129 | * BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.96274629 |
130 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 0.95080835 |
131 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.94809810 |
132 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.93958946 |
133 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 0.93952514 |
134 | KDM2B_26808549_Chip-Seq_DND41_Human | 0.93915553 |
135 | REST_21632747_ChIP-Seq_MESCs_Mouse | 0.93839119 |
136 | VDR_24787735_ChIP-Seq_THP-1_Human | 0.93717383 |
137 | RAC3_21632823_ChIP-Seq_H3396_Human | 0.92859757 |
138 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.92617087 |
139 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.91498801 |
140 | TCF7_22412390_ChIP-Seq_EML_Mouse | 0.91233905 |
141 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 0.89739063 |
142 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.88984477 |
143 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.88892727 |
144 | GF1_26923725_Chip-Seq_HPCs_Mouse | 0.88797649 |
145 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.88745032 |
146 | TP53_16413492_ChIP-PET_HCT116_Human | 0.88470356 |
147 | AR_21572438_ChIP-Seq_LNCaP_Human | 0.87947046 |
148 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 0.87916079 |
149 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 0.87613597 |
150 | * FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.87046694 |
151 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.86827616 |
152 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 0.86402102 |
153 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.86369858 |
154 | MYB_26560356_Chip-Seq_TH2_Human | 0.86155623 |
155 | CTCF_21964334_ChIP-Seq_BJAB-B_Human | 0.85536108 |
156 | HNFA_21074721_ChIP-Seq_CACO-2_Human | 0.85286014 |
157 | NFYA_21822215_ChIP-Seq_K562_Human | 0.84759220 |
158 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 0.84695145 |
159 | P63_20808887_ChIP-Seq_KERATINOCYTES_Human | 0.84295293 |
160 | GATA1_19941826_ChIP-Seq_K562_Human | 0.83668489 |
161 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.81826861 |
162 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.81582826 |
163 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.80876937 |
164 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.80876937 |
165 | * EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.80144757 |
166 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 0.79630579 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0001986_abnormal_taste_sensitivity | 3.97449932 |
2 | MP0000569_abnormal_digit_pigmentation | 3.38851050 |
3 | MP0004381_abnormal_hair_follicle | 3.10209794 |
4 | MP0001835_abnormal_antigen_presentation | 2.94526676 |
5 | MP0005174_abnormal_tail_pigmentation | 2.69288451 |
6 | MP0006292_abnormal_olfactory_placode | 2.61384795 |
7 | MP0001800_abnormal_humoral_immune | 2.52394365 |
8 | MP0001790_abnormal_immune_system | 2.37795190 |
9 | MP0005387_immune_system_phenotype | 2.37795190 |
10 | MP0002277_abnormal_respiratory_mucosa | 2.36398611 |
11 | MP0005671_abnormal_response_to | 2.21419432 |
12 | MP0001188_hyperpigmentation | 2.20605424 |
13 | MP0002396_abnormal_hematopoietic_system | 2.09820714 |
14 | MP0002254_reproductive_system_inflammat | 2.05801861 |
15 | MP0002102_abnormal_ear_morphology | 2.04959479 |
16 | MP0000015_abnormal_ear_pigmentation | 1.93787656 |
17 | MP0002452_abnormal_antigen_presenting | 1.91988325 |
18 | MP0002723_abnormal_immune_serum | 1.90427948 |
19 | MP0003763_abnormal_thymus_physiology | 1.86242117 |
20 | MP0005670_abnormal_white_adipose | 1.84140475 |
21 | MP0004130_abnormal_muscle_cell | 1.82434816 |
22 | MP0003136_yellow_coat_color | 1.78433120 |
23 | MP0005365_abnormal_bile_salt | 1.76882938 |
24 | MP0008872_abnormal_physiological_respon | 1.75825550 |
25 | MP0005451_abnormal_body_composition | 1.73290577 |
26 | MP0005000_abnormal_immune_tolerance | 1.72086804 |
27 | MP0009764_decreased_sensitivity_to | 1.69800540 |
28 | MP0008995_early_reproductive_senescence | 1.68157289 |
29 | MP0008058_abnormal_DNA_repair | 1.65616682 |
30 | MP0003787_abnormal_imprinting | 1.62849411 |
31 | MP0005464_abnormal_platelet_physiology | 1.62455779 |
32 | MP0005025_abnormal_response_to | 1.62445226 |
33 | MP0003195_calcinosis | 1.61696936 |
34 | MP0002420_abnormal_adaptive_immunity | 1.61421148 |
35 | MP0002653_abnormal_ependyma_morphology | 1.61416119 |
36 | MP0002419_abnormal_innate_immunity | 1.61358339 |
37 | MP0001819_abnormal_immune_cell | 1.60745623 |
38 | MP0000566_synostosis | 1.60634549 |
39 | MP0003866_abnormal_defecation | 1.60369698 |
40 | MP0005645_abnormal_hypothalamus_physiol | 1.59532319 |
41 | MP0000685_abnormal_immune_system | 1.58187032 |
42 | MP0008057_abnormal_DNA_replication | 1.56492840 |
43 | MP0002163_abnormal_gland_morphology | 1.55595300 |
44 | MP0000383_abnormal_hair_follicle | 1.54871226 |
45 | MP0003646_muscle_fatigue | 1.53495298 |
46 | MP0005083_abnormal_biliary_tract | 1.49637865 |
47 | MP0004019_abnormal_vitamin_homeostasis | 1.49231012 |
48 | MP0002933_joint_inflammation | 1.48509192 |
49 | MP0005310_abnormal_salivary_gland | 1.48064803 |
50 | MP0001968_abnormal_touch/_nociception | 1.47896992 |
51 | MP0002876_abnormal_thyroid_physiology | 1.46194069 |
52 | MP0000579_abnormal_nail_morphology | 1.44543780 |
53 | MP0002928_abnormal_bile_duct | 1.41378166 |
54 | MP0002148_abnormal_hypersensitivity_rea | 1.39621730 |
55 | MP0000716_abnormal_immune_system | 1.39214719 |
56 | MP0001873_stomach_inflammation | 1.36930205 |
57 | MP0003436_decreased_susceptibility_to | 1.36738654 |
58 | MP0005075_abnormal_melanosome_morpholog | 1.35653275 |
59 | MP0000371_diluted_coat_color | 1.35130244 |
60 | MP0009785_altered_susceptibility_to | 1.34500175 |
61 | MP0008877_abnormal_DNA_methylation | 1.33521808 |
62 | MP0002398_abnormal_bone_marrow | 1.33388756 |
63 | MP0005423_abnormal_somatic_nervous | 1.31411200 |
64 | MP0004043_abnormal_pH_regulation | 1.31402472 |
65 | MP0004142_abnormal_muscle_tone | 1.27886611 |
66 | MP0003252_abnormal_bile_duct | 1.24327669 |
67 | MP0002638_abnormal_pupillary_reflex | 1.23950797 |
68 | MP0003183_abnormal_peptide_metabolism | 1.23627722 |
69 | MP0002095_abnormal_skin_pigmentation | 1.20386671 |
70 | MP0005360_urolithiasis | 1.18633977 |
71 | MP0010155_abnormal_intestine_physiology | 1.18350891 |
72 | MP0000689_abnormal_spleen_morphology | 1.17993482 |
73 | MP0002006_tumorigenesis | 1.17953198 |
74 | MP0005647_abnormal_sex_gland | 1.16400839 |
75 | MP0002138_abnormal_hepatobiliary_system | 1.14935096 |
76 | MP0003868_abnormal_feces_composition | 1.14854803 |
77 | MP0002166_altered_tumor_susceptibility | 1.14404103 |
78 | MP0001346_abnormal_lacrimal_gland | 1.11640409 |
79 | MP0008260_abnormal_autophagy | 1.11108019 |
80 | MP0003941_abnormal_skin_development | 1.10372251 |
81 | MP0005389_reproductive_system_phenotype | 1.10196299 |
82 | MP0000490_abnormal_crypts_of | 1.08931611 |
83 | MP0003045_fibrosis | 1.06534997 |
84 | MP0001485_abnormal_pinna_reflex | 1.04308889 |
85 | MP0001845_abnormal_inflammatory_respons | 1.03131963 |
86 | MP0002160_abnormal_reproductive_system | 1.03111650 |
87 | MP0002722_abnormal_immune_system | 1.02393535 |
88 | MP0005085_abnormal_gallbladder_physiolo | 1.02131558 |
89 | MP0004742_abnormal_vestibular_system | 1.00527412 |
90 | MP0003303_peritoneal_inflammation | 0.99386763 |
91 | MP0009745_abnormal_behavioral_response | 0.99223755 |
92 | MP0006082_CNS_inflammation | 0.98960849 |
93 | MP0005379_endocrine/exocrine_gland_phen | 0.98073207 |
94 | MP0002429_abnormal_blood_cell | 0.97936934 |
95 | MP0001501_abnormal_sleep_pattern | 0.97878662 |
96 | MP0003111_abnormal_nucleus_morphology | 0.97557173 |
97 | MP0001765_abnormal_ion_homeostasis | 0.96636437 |
98 | MP0009278_abnormal_bone_marrow | 0.95987250 |
99 | MP0003724_increased_susceptibility_to | 0.95351034 |
100 | MP0004808_abnormal_hematopoietic_stem | 0.94850030 |
101 | MP0000703_abnormal_thymus_morphology | 0.94543809 |
102 | MP0004947_skin_inflammation | 0.92872187 |
103 | MP0001663_abnormal_digestive_system | 0.91832108 |
104 | MP0005448_abnormal_energy_balance | 0.89437087 |
105 | MP0002075_abnormal_coat/hair_pigmentati | 0.89052371 |
106 | MP0005409_darkened_coat_color | 0.88889800 |
107 | MP0004145_abnormal_muscle_electrophysio | 0.87683529 |
108 | MP0001186_pigmentation_phenotype | 0.85951136 |
109 | MP0003172_abnormal_lysosome_physiology | 0.85883778 |
110 | MP0004885_abnormal_endolymph | 0.85371476 |
111 | MP0009046_muscle_twitch | 0.85357616 |
112 | MP0001502_abnormal_circadian_rhythm | 0.85277553 |
113 | MP0004134_abnormal_chest_morphology | 0.84925048 |
114 | MP0000631_abnormal_neuroendocrine_gland | 0.84624335 |
115 | MP0002064_seizures | 0.83416480 |
116 | MP0009333_abnormal_splenocyte_physiolog | 0.82974689 |
117 | MP0008961_abnormal_basal_metabolism | 0.80716672 |
118 | MP0002405_respiratory_system_inflammati | 0.80525587 |
119 | MP0002693_abnormal_pancreas_physiology | 0.79142876 |
120 | MP0008469_abnormal_protein_level | 0.78102101 |
121 | MP0001919_abnormal_reproductive_system | 0.77960922 |
122 | MP0001533_abnormal_skeleton_physiology | 0.77932449 |
123 | MP0005551_abnormal_eye_electrophysiolog | 0.77795159 |
124 | MP0005397_hematopoietic_system_phenotyp | 0.76621479 |
125 | MP0001545_abnormal_hematopoietic_system | 0.76621479 |
126 | MP0005257_abnormal_intraocular_pressure | 0.75634810 |
127 | MP0002272_abnormal_nervous_system | 0.75606798 |
128 | MP0002136_abnormal_kidney_physiology | 0.75076610 |
129 | MP0008875_abnormal_xenobiotic_pharmacok | 0.74504540 |
130 | MP0005646_abnormal_pituitary_gland | 0.74432184 |
131 | MP0002009_preneoplasia | 0.73143938 |
132 | MP0010678_abnormal_skin_adnexa | 0.73023407 |
133 | MP0001970_abnormal_pain_threshold | 0.72345428 |
134 | MP0010329_abnormal_lipoprotein_level | 0.72230626 |
135 | MP0000465_gastrointestinal_hemorrhage | 0.71475936 |
136 | MP0001119_abnormal_female_reproductive | 0.71165700 |
137 | MP0000470_abnormal_stomach_morphology | 0.70850596 |
138 | MP0005377_hearing/vestibular/ear_phenot | 0.70051960 |
139 | MP0003878_abnormal_ear_physiology | 0.70051960 |
140 | MP0000427_abnormal_hair_cycle | 0.68595076 |
141 | MP0002735_abnormal_chemical_nociception | 0.68391917 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 5.98200659 |
2 | Chromsome breakage (HP:0040012) | 5.29581691 |
3 | Genetic anticipation (HP:0003743) | 4.60498699 |
4 | Prostate neoplasm (HP:0100787) | 4.40974711 |
5 | Congenital stationary night blindness (HP:0007642) | 3.82557317 |
6 | Pancreatic cysts (HP:0001737) | 3.60119149 |
7 | Abnormality of the fingertips (HP:0001211) | 3.46369237 |
8 | Agammaglobulinemia (HP:0004432) | 3.36059471 |
9 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.26336317 |
10 | Recurrent cutaneous fungal infections (HP:0011370) | 3.24237934 |
11 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.24237934 |
12 | Progressive cerebellar ataxia (HP:0002073) | 3.23863571 |
13 | Duplicated collecting system (HP:0000081) | 3.11318615 |
14 | IgG deficiency (HP:0004315) | 3.05425897 |
15 | Abnormality of DNA repair (HP:0003254) | 3.03147366 |
16 | Pendular nystagmus (HP:0012043) | 3.00833682 |
17 | Clubbing of toes (HP:0100760) | 3.00696776 |
18 | Pancreatic fibrosis (HP:0100732) | 2.88807689 |
19 | Abnormality of the renal collecting system (HP:0004742) | 2.86520278 |
20 | Abnormality of the prostate (HP:0008775) | 2.85209892 |
21 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.85150874 |
22 | Severe combined immunodeficiency (HP:0004430) | 2.79583421 |
23 | Panhypogammaglobulinemia (HP:0003139) | 2.79227188 |
24 | Abnormality of midbrain morphology (HP:0002418) | 2.76706496 |
25 | Molar tooth sign on MRI (HP:0002419) | 2.76706496 |
26 | Recurrent fungal infections (HP:0002841) | 2.75447423 |
27 | Colitis (HP:0002583) | 2.74525239 |
28 | True hermaphroditism (HP:0010459) | 2.73476685 |
29 | Lip pit (HP:0100267) | 2.72679418 |
30 | Recurrent sinusitis (HP:0011108) | 2.70068272 |
31 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.64215619 |
32 | Abolished electroretinogram (ERG) (HP:0000550) | 2.63204345 |
33 | Ectopic kidney (HP:0000086) | 2.60714005 |
34 | Inflammation of the large intestine (HP:0002037) | 2.58383177 |
35 | Cystic liver disease (HP:0006706) | 2.57776275 |
36 | Joint hemorrhage (HP:0005261) | 2.57344419 |
37 | Decreased central vision (HP:0007663) | 2.55297481 |
38 | Recurrent abscess formation (HP:0002722) | 2.54988281 |
39 | Recurrent bacterial skin infections (HP:0005406) | 2.52246824 |
40 | Hemiplegia (HP:0002301) | 2.51997104 |
41 | Stomach cancer (HP:0012126) | 2.49913199 |
42 | Abnormality of T cell number (HP:0011839) | 2.49688220 |
43 | Abnormality of the preputium (HP:0100587) | 2.48867605 |
44 | Clumsiness (HP:0002312) | 2.46293303 |
45 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 2.45851490 |
46 | Decreased circulating renin level (HP:0003351) | 2.43758121 |
47 | T lymphocytopenia (HP:0005403) | 2.43100033 |
48 | Abnormality of T cells (HP:0002843) | 2.42579913 |
49 | Nephronophthisis (HP:0000090) | 2.40958642 |
50 | Chronic diarrhea (HP:0002028) | 2.40831876 |
51 | Prolonged bleeding time (HP:0003010) | 2.40245199 |
52 | Abnormality of the renal cortex (HP:0011035) | 2.39351000 |
53 | Eczematoid dermatitis (HP:0000976) | 2.38771015 |
54 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.38511686 |
55 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.36740958 |
56 | Impaired smooth pursuit (HP:0007772) | 2.36371648 |
57 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.35763145 |
58 | Absent/shortened dynein arms (HP:0200106) | 2.35763145 |
59 | Cheilitis (HP:0100825) | 2.35650719 |
60 | Acute lymphatic leukemia (HP:0006721) | 2.35465496 |
61 | Gaze-evoked nystagmus (HP:0000640) | 2.35273169 |
62 | Recurrent skin infections (HP:0001581) | 2.34957516 |
63 | Asplenia (HP:0001746) | 2.31524553 |
64 | IgM deficiency (HP:0002850) | 2.29479463 |
65 | Anal stenosis (HP:0002025) | 2.28117252 |
66 | Meckel diverticulum (HP:0002245) | 2.28113499 |
67 | Abnormality of chromosome stability (HP:0003220) | 2.27621990 |
68 | Recurrent viral infections (HP:0004429) | 2.27057386 |
69 | Febrile seizures (HP:0002373) | 2.25867915 |
70 | Attenuation of retinal blood vessels (HP:0007843) | 2.25866850 |
71 | Orchitis (HP:0100796) | 2.25505742 |
72 | Meningitis (HP:0001287) | 2.25486780 |
73 | Recurrent bronchitis (HP:0002837) | 2.25244126 |
74 | Abnormality of the ileum (HP:0001549) | 2.25139109 |
75 | Abnormality of binocular vision (HP:0011514) | 2.22850967 |
76 | Diplopia (HP:0000651) | 2.22850967 |
77 | Abnormality of T cell physiology (HP:0011840) | 2.21237078 |
78 | Gastrointestinal inflammation (HP:0004386) | 2.20771734 |
79 | Leukopenia (HP:0001882) | 2.19332777 |
80 | Gingival bleeding (HP:0000225) | 2.18805145 |
81 | Abnormality of B cell number (HP:0010975) | 2.18240584 |
82 | Abnormality of eosinophils (HP:0001879) | 2.16593957 |
83 | Vasculitis (HP:0002633) | 2.15471201 |
84 | Abnormality of the renal medulla (HP:0100957) | 2.15306535 |
85 | Gastrointestinal infarctions (HP:0005244) | 2.14257699 |
86 | Upper limb muscle weakness (HP:0003484) | 2.13654155 |
87 | Autoimmune thrombocytopenia (HP:0001973) | 2.12474312 |
88 | Abnormality of the carotid arteries (HP:0005344) | 2.12092731 |
89 | Mediastinal lymphadenopathy (HP:0100721) | 2.11324083 |
90 | Septo-optic dysplasia (HP:0100842) | 2.10933888 |
91 | Gingivitis (HP:0000230) | 2.09886117 |
92 | Hyperventilation (HP:0002883) | 2.07252336 |
93 | Pustule (HP:0200039) | 2.05569381 |
94 | Abnormal drinking behavior (HP:0030082) | 2.04703774 |
95 | Polydipsia (HP:0001959) | 2.04703774 |
96 | Hypochromic anemia (HP:0001931) | 2.04091122 |
97 | Severe visual impairment (HP:0001141) | 2.03756558 |
98 | Obstructive lung disease (HP:0006536) | 2.02469807 |
99 | Chronic obstructive pulmonary disease (HP:0006510) | 2.02469807 |
100 | Progressive inability to walk (HP:0002505) | 1.99056233 |
101 | Bony spicule pigmentary retinopathy (HP:0007737) | 1.99011465 |
102 | Tubular atrophy (HP:0000092) | 1.97925269 |
103 | Retrobulbar optic neuritis (HP:0100654) | 1.97097538 |
104 | Optic neuritis (HP:0100653) | 1.97097538 |
105 | Encephalitis (HP:0002383) | 1.96642171 |
106 | Ectropion (HP:0000656) | 1.96523626 |
107 | Furrowed tongue (HP:0000221) | 1.94779384 |
108 | Abnormality of ocular smooth pursuit (HP:0000617) | 1.93656431 |
109 | Inability to walk (HP:0002540) | 1.92979463 |
110 | Congenital sensorineural hearing impairment (HP:0008527) | 1.92917367 |
111 | Protruding tongue (HP:0010808) | 1.91884892 |
112 | Lymphopenia (HP:0001888) | 1.91710084 |
113 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 1.90896839 |
114 | Visual hallucinations (HP:0002367) | 1.90497434 |
115 | Periodontitis (HP:0000704) | 1.90088561 |
116 | Reticulocytopenia (HP:0001896) | 1.88306528 |
117 | Aplasia/Hypoplasia of the patella (HP:0006498) | 1.85428558 |
118 | Epistaxis (HP:0000421) | 1.84914702 |
119 | Chronic hepatic failure (HP:0100626) | 1.84608757 |
120 | Hemoptysis (HP:0002105) | 1.84481789 |
121 | Autoimmune hemolytic anemia (HP:0001890) | 1.83246639 |
122 | Keratoconus (HP:0000563) | 1.82477335 |
123 | Increased corneal curvature (HP:0100692) | 1.82477335 |
124 | IgA deficiency (HP:0002720) | 1.82244255 |
125 | Gastrointestinal stroma tumor (HP:0100723) | 1.82044971 |
126 | Abnormality of the nasal septum (HP:0000419) | 1.80716328 |
127 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 1.80395705 |
128 | Combined immunodeficiency (HP:0005387) | 1.80295180 |
129 | Concave nail (HP:0001598) | 1.80055870 |
130 | Myocardial infarction (HP:0001658) | 1.79546977 |
131 | Granulocytopenia (HP:0001913) | 1.78049766 |
132 | Tetany (HP:0001281) | 1.76826668 |
133 | Osteomalacia (HP:0002749) | 1.76475773 |
134 | Abnormality of male internal genitalia (HP:0000022) | 1.75939414 |
135 | Patellar aplasia (HP:0006443) | 1.75740254 |
136 | Eosinophilia (HP:0001880) | 1.74964791 |
137 | Leukocytosis (HP:0001974) | 1.74903323 |
138 | Hypoplasia of the thymus (HP:0000778) | 1.74574642 |
139 | Bile duct proliferation (HP:0001408) | 1.74002703 |
140 | Abnormal biliary tract physiology (HP:0012439) | 1.74002703 |
141 | Confusion (HP:0001289) | 1.73842596 |
142 | Tented upper lip vermilion (HP:0010804) | 1.73801237 |
143 | Oligodactyly (hands) (HP:0001180) | 1.71745613 |
144 | Abnormality of pyrimidine metabolism (HP:0004353) | 1.71593840 |
145 | Thyroiditis (HP:0100646) | 1.71155199 |
146 | Renal cortical cysts (HP:0000803) | 1.70919625 |
147 | Fair hair (HP:0002286) | 1.69317187 |
148 | Generalized hypopigmentation of hair (HP:0011358) | 1.68610398 |
149 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.66664897 |
150 | Abnormality of the hepatic vasculature (HP:0006707) | 1.65064996 |
151 | Increased IgE level (HP:0003212) | 1.64761978 |
152 | Menorrhagia (HP:0000132) | 1.63184595 |
153 | Recurrent pneumonia (HP:0006532) | 1.62479613 |
154 | Anal atresia (HP:0002023) | 1.62465153 |
155 | Chronic otitis media (HP:0000389) | 1.61881315 |
156 | Stomatitis (HP:0010280) | 1.61630024 |
157 | Myelodysplasia (HP:0002863) | 1.60379605 |
158 | Anomalous pulmonary venous return (HP:0010772) | 1.59441352 |
159 | Pulmonary infiltrates (HP:0002113) | 1.58261838 |
160 | Myositis (HP:0100614) | 1.58162019 |
161 | Acute myeloid leukemia (HP:0004808) | 1.58134196 |
162 | Distal lower limb muscle weakness (HP:0009053) | 1.57766470 |
163 | Prolonged partial thromboplastin time (HP:0003645) | 1.56605116 |
164 | Abnormality of the intervertebral disk (HP:0005108) | 1.55977457 |
165 | Albinism (HP:0001022) | 1.54158914 |
166 | Elfin facies (HP:0004428) | 1.52947656 |
Rank | Gene Set | Z-score |
---|---|---|
1 | IRAK3 | 4.10696843 |
2 | INSRR | 3.00409701 |
3 | MAP4K1 | 2.90206705 |
4 | TXK | 2.66031037 |
5 | TAOK3 | 2.31203974 |
6 | IRAK4 | 2.29244953 |
7 | CDK12 | 2.25879933 |
8 | MAP3K14 | 2.10190810 |
9 | GRK6 | 2.05649494 |
10 | MAP3K13 | 2.00931795 |
11 | EIF2AK2 | 1.99314590 |
12 | ACVR1B | 1.95487971 |
13 | LATS1 | 1.95148087 |
14 | BRD4 | 1.94179654 |
15 | BLK | 1.91420311 |
16 | JAK1 | 1.84980767 |
17 | FGFR4 | 1.83597135 |
18 | JAK3 | 1.81631796 |
19 | TNK2 | 1.80993414 |
20 | IKBKE | 1.79381095 |
21 | WNK4 | 1.78374642 |
22 | CAMK1D | 1.75570161 |
23 | CAMKK2 | 1.67484216 |
24 | TNIK | 1.65364580 |
25 | TYK2 | 1.63369702 |
26 | GRK1 | 1.61936683 |
27 | CAMKK1 | 1.61068214 |
28 | IKBKB | 1.60369480 |
29 | SIK2 | 1.59029164 |
30 | CAMK1G | 1.56236312 |
31 | TEC | 1.52413917 |
32 | BMPR1B | 1.52202640 |
33 | KIT | 1.48986951 |
34 | ZAK | 1.48113594 |
35 | IRAK1 | 1.43327355 |
36 | MAP2K6 | 1.39002516 |
37 | MST1R | 1.38420354 |
38 | NLK | 1.31193749 |
39 | DAPK2 | 1.24402848 |
40 | ADRBK2 | 1.21007825 |
41 | BTK | 1.17427236 |
42 | IRAK2 | 1.17132774 |
43 | CASK | 1.13545970 |
44 | CDK3 | 1.12900093 |
45 | TGFBR2 | 1.12681502 |
46 | CHUK | 1.10012281 |
47 | HCK | 1.09995383 |
48 | PRKCQ | 1.07914772 |
49 | PKN1 | 1.07899113 |
50 | RIPK4 | 1.07299614 |
51 | PRKD2 | 1.06959508 |
52 | YES1 | 1.02479274 |
53 | PRKCH | 1.01621608 |
54 | NTRK2 | 0.93892558 |
55 | TRIB3 | 0.92716864 |
56 | STK38 | 0.91677296 |
57 | MAP3K6 | 0.91376732 |
58 | PRKAA2 | 0.90706603 |
59 | FGFR3 | 0.90329230 |
60 | EPHA3 | 0.89421913 |
61 | SYK | 0.88771856 |
62 | NEK6 | 0.88469244 |
63 | CSF1R | 0.87280482 |
64 | MAP2K3 | 0.86935914 |
65 | MARK2 | 0.86798362 |
66 | MAPK13 | 0.85252846 |
67 | RPS6KA6 | 0.84242034 |
68 | LYN | 0.82408601 |
69 | PIK3CG | 0.82215037 |
70 | PTK2B | 0.81322451 |
71 | PASK | 0.81011894 |
72 | MARK3 | 0.80807585 |
73 | MAP3K11 | 0.78840849 |
74 | SRPK1 | 0.78349546 |
75 | CDK9 | 0.77808224 |
76 | PINK1 | 0.77706617 |
77 | ITK | 0.76175378 |
78 | LCK | 0.75039781 |
79 | SGK2 | 0.74238951 |
80 | ADRBK1 | 0.73702677 |
81 | PRPF4B | 0.72504703 |
82 | MAP4K2 | 0.72216219 |
83 | WNK1 | 0.71916760 |
84 | FES | 0.71628983 |
85 | STK11 | 0.71618033 |
86 | DYRK3 | 0.71578126 |
87 | TYRO3 | 0.71432987 |
88 | ZAP70 | 0.71237631 |
89 | FGFR2 | 0.71236900 |
90 | CDC42BPA | 0.70874032 |
91 | TLK1 | 0.70416122 |
92 | MAP2K2 | 0.69393903 |
93 | HIPK2 | 0.69194402 |
94 | MARK1 | 0.69105911 |
95 | PDK1 | 0.69065863 |
96 | MAPKAPK3 | 0.66501456 |
97 | CAMK1 | 0.65509059 |
98 | ATR | 0.64042892 |
99 | MAPK7 | 0.63960295 |
100 | MAPK12 | 0.63060746 |
101 | CSK | 0.62534761 |
102 | MAP3K7 | 0.61266277 |
103 | FRK | 0.61058883 |
104 | MKNK2 | 0.60952384 |
105 | MAPK11 | 0.60242193 |
106 | JAK2 | 0.60171170 |
107 | MELK | 0.59249092 |
108 | STK38L | 0.58956676 |
109 | TBK1 | 0.58830310 |
110 | NUAK1 | 0.58547227 |
111 | PIM1 | 0.57907930 |
112 | EPHB1 | 0.57769658 |
113 | SIK1 | 0.56392234 |
114 | PLK4 | 0.56364839 |
115 | STK4 | 0.55858645 |
116 | RPS6KA5 | 0.54140751 |
117 | OXSR1 | 0.51913522 |
118 | CLK1 | 0.51727759 |
119 | SGK3 | 0.51365844 |
120 | ABL1 | 0.48762846 |
121 | SGK1 | 0.48670990 |
122 | SGK223 | 0.47681781 |
123 | SGK494 | 0.47681781 |
124 | RPS6KC1 | 0.46240353 |
125 | RPS6KL1 | 0.46240353 |
126 | CAMK4 | 0.45684383 |
127 | ERBB2 | 0.44015545 |
128 | CDK7 | 0.43929300 |
129 | PRKAA1 | 0.40552236 |
130 | TRPM7 | 0.39857504 |
131 | PRKCI | 0.38408554 |
132 | PDGFRB | 0.37847043 |
133 | PIK3CA | 0.36713743 |
134 | GRK7 | 0.36176578 |
135 | MAPKAPK5 | 0.36077849 |
136 | MAP3K1 | 0.35808215 |
137 | BMX | 0.35801887 |
138 | NEK2 | 0.35719315 |
139 | FLT3 | 0.35110114 |
140 | MAPK15 | 0.34783003 |
141 | EPHA2 | 0.34312417 |
142 | CHEK2 | 0.34300291 |
143 | MAPK3 | 0.32097283 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.82054982 |
2 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.53750815 |
3 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 2.32676446 |
4 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.27094534 |
5 | ABC transporters_Homo sapiens_hsa02010 | 2.13422545 |
6 | Lysine degradation_Homo sapiens_hsa00310 | 2.06736948 |
7 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.01904244 |
8 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.94958219 |
9 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 1.84088615 |
10 | Other glycan degradation_Homo sapiens_hsa00511 | 1.80715509 |
11 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.79168811 |
12 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.75150225 |
13 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.71325822 |
14 | Phototransduction_Homo sapiens_hsa04744 | 1.64997298 |
15 | Measles_Homo sapiens_hsa05162 | 1.58906151 |
16 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.58376056 |
17 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.56530614 |
18 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.51169143 |
19 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.50516605 |
20 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.44525449 |
21 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.41081847 |
22 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.36464483 |
23 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.34323289 |
24 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.33437629 |
25 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.29090601 |
26 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.29082933 |
27 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.28342625 |
28 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.27622588 |
29 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.24948333 |
30 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.24816250 |
31 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.22198353 |
32 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.21850103 |
33 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 1.20787720 |
34 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.19655088 |
35 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.19620618 |
36 | Leishmaniasis_Homo sapiens_hsa05140 | 1.17600043 |
37 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.09788867 |
38 | Retinol metabolism_Homo sapiens_hsa00830 | 1.08508183 |
39 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 1.06462773 |
40 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.06316792 |
41 | Nicotine addiction_Homo sapiens_hsa05033 | 1.06049872 |
42 | Influenza A_Homo sapiens_hsa05164 | 1.03600809 |
43 | Allograft rejection_Homo sapiens_hsa05330 | 1.03263873 |
44 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.99020197 |
45 | Histidine metabolism_Homo sapiens_hsa00340 | 0.98146170 |
46 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.97762880 |
47 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.96430091 |
48 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.96291886 |
49 | Sulfur relay system_Homo sapiens_hsa04122 | 0.95989924 |
50 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.94781549 |
51 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.94029757 |
52 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.93677496 |
53 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.92571792 |
54 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.91752612 |
55 | Homologous recombination_Homo sapiens_hsa03440 | 0.91137305 |
56 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.88354417 |
57 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.86510988 |
58 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.85932050 |
59 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.85629692 |
60 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.83177771 |
61 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.81463409 |
62 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.81020189 |
63 | Asthma_Homo sapiens_hsa05310 | 0.78587146 |
64 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.77211403 |
65 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.76737765 |
66 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.76587276 |
67 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.76483093 |
68 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.75614602 |
69 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.74651037 |
70 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.74422428 |
71 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.72669997 |
72 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.71777231 |
73 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.70963869 |
74 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.70935890 |
75 | Taste transduction_Homo sapiens_hsa04742 | 0.70827757 |
76 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.70235797 |
77 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.67720916 |
78 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.67427262 |
79 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.66955653 |
80 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.65316137 |
81 | Hepatitis C_Homo sapiens_hsa05160 | 0.65035878 |
82 | Malaria_Homo sapiens_hsa05144 | 0.64871035 |
83 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.64451995 |
84 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.63977504 |
85 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.62450906 |
86 | Tuberculosis_Homo sapiens_hsa05152 | 0.59657364 |
87 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.58536403 |
88 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.56480187 |
89 | Circadian entrainment_Homo sapiens_hsa04713 | 0.55261560 |
90 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.54753018 |
91 | Olfactory transduction_Homo sapiens_hsa04740 | 0.54274023 |
92 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.54139227 |
93 | Insulin secretion_Homo sapiens_hsa04911 | 0.53608365 |
94 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.53472679 |
95 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.53059493 |
96 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.52410228 |
97 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.52378204 |
98 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.51839382 |
99 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.51791062 |
100 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.50925326 |
101 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.50818312 |
102 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.50060428 |
103 | Hepatitis B_Homo sapiens_hsa05161 | 0.49449577 |
104 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.49143068 |
105 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.49059796 |
106 | Salivary secretion_Homo sapiens_hsa04970 | 0.47798275 |
107 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.47152691 |
108 | Apoptosis_Homo sapiens_hsa04210 | 0.47068212 |
109 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.46516442 |
110 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.46303672 |
111 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.46099870 |
112 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.44234719 |
113 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.43279601 |
114 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.42654432 |
115 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.41968308 |
116 | Viral myocarditis_Homo sapiens_hsa05416 | 0.41955539 |
117 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.41651228 |
118 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.41590647 |
119 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.41183899 |
120 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.40862169 |
121 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.40613291 |
122 | Morphine addiction_Homo sapiens_hsa05032 | 0.40368533 |
123 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.40344673 |
124 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.40099690 |
125 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.39835910 |
126 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.39808993 |
127 | Peroxisome_Homo sapiens_hsa04146 | 0.39752955 |
128 | Insulin resistance_Homo sapiens_hsa04931 | 0.39404327 |
129 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.38576192 |
130 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.36934213 |
131 | Platelet activation_Homo sapiens_hsa04611 | 0.35139081 |