Rank | Gene Set | Z-score |
---|---|---|
1 | * keratinization (GO:0031424) | 9.89062566 |
2 | * establishment of skin barrier (GO:0061436) | 7.57507224 |
3 | * regulation of water loss via skin (GO:0033561) | 7.50325587 |
4 | intermediate filament organization (GO:0045109) | 7.35624630 |
5 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 6.39277651 |
6 | interferon-gamma secretion (GO:0072643) | 6.01157923 |
7 | surfactant homeostasis (GO:0043129) | 5.79541775 |
8 | keratinocyte differentiation (GO:0030216) | 5.54716211 |
9 | gap junction assembly (GO:0016264) | 5.41824366 |
10 | intestinal epithelial cell development (GO:0060576) | 5.39833039 |
11 | peptide cross-linking (GO:0018149) | 5.25671822 |
12 | negative regulation of macroautophagy (GO:0016242) | 5.04179628 |
13 | epidermis development (GO:0008544) | 4.95824242 |
14 | * multicellular organismal water homeostasis (GO:0050891) | 4.79961584 |
15 | chemical homeostasis within a tissue (GO:0048875) | 4.73958705 |
16 | skin morphogenesis (GO:0043589) | 4.68257817 |
17 | establishment of tissue polarity (GO:0007164) | 4.61747121 |
18 | establishment of planar polarity (GO:0001736) | 4.61747121 |
19 | intermediate filament cytoskeleton organization (GO:0045104) | 4.56096754 |
20 | epidermal cell differentiation (GO:0009913) | 4.45424091 |
21 | intermediate filament-based process (GO:0045103) | 4.45181936 |
22 | polarized epithelial cell differentiation (GO:0030859) | 4.39805826 |
23 | positive regulation of keratinocyte differentiation (GO:0045618) | 4.30381018 |
24 | epithelial cell differentiation involved in prostate gland development (GO:0060742) | 4.22370963 |
25 | * negative regulation of keratinocyte proliferation (GO:0010839) | 4.18378524 |
26 | ectoderm development (GO:0007398) | 4.15960187 |
27 | epithelial cell-cell adhesion (GO:0090136) | 4.14738184 |
28 | cell-substrate junction assembly (GO:0007044) | 4.14700880 |
29 | * regulation of keratinocyte proliferation (GO:0010837) | 4.13878259 |
30 | lung-associated mesenchyme development (GO:0060484) | 4.12312610 |
31 | ribosome assembly (GO:0042255) | 4.07066030 |
32 | * water homeostasis (GO:0030104) | 3.95032053 |
33 | positive regulation of hair cycle (GO:0042635) | 3.92230124 |
34 | positive regulation of hair follicle development (GO:0051798) | 3.92230124 |
35 | protein localization to endosome (GO:0036010) | 3.88276472 |
36 | dichotomous subdivision of an epithelial terminal unit (GO:0060600) | 3.85555545 |
37 | regulation of hair follicle development (GO:0051797) | 3.80848624 |
38 | adhesion of symbiont to host cell (GO:0044650) | 3.68244229 |
39 | virion attachment to host cell (GO:0019062) | 3.68244229 |
40 | cell adhesion mediated by integrin (GO:0033627) | 3.66772064 |
41 | negative regulation of chondrocyte differentiation (GO:0032331) | 3.62038281 |
42 | trophectodermal cell differentiation (GO:0001829) | 3.61775614 |
43 | * positive regulation of epidermal cell differentiation (GO:0045606) | 3.48740709 |
44 | lateral sprouting from an epithelium (GO:0060601) | 3.43267717 |
45 | long-chain fatty acid biosynthetic process (GO:0042759) | 3.40464952 |
46 | maturation of SSU-rRNA (GO:0030490) | 3.38745499 |
47 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 3.38458225 |
48 | cell junction assembly (GO:0034329) | 3.35755748 |
49 | hypotonic response (GO:0006971) | 3.33933734 |
50 | negative regulation of cell fate specification (GO:0009996) | 3.31063622 |
51 | keratinocyte proliferation (GO:0043616) | 3.27527179 |
52 | epithelium development (GO:0060429) | 3.27473668 |
53 | formation of translation preinitiation complex (GO:0001731) | 3.26476608 |
54 | cell junction organization (GO:0034330) | 3.25732677 |
55 | regulation of cardioblast differentiation (GO:0051890) | 3.24957025 |
56 | regulation of Wnt signaling pathway involved in heart development (GO:0003307) | 3.24002013 |
57 | regulation of keratinocyte differentiation (GO:0045616) | 3.23522956 |
58 | ribosomal small subunit biogenesis (GO:0042274) | 3.20713815 |
59 | skin development (GO:0043588) | 3.19197927 |
60 | purine nucleobase biosynthetic process (GO:0009113) | 3.17249386 |
61 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 3.15527891 |
62 | * regulation of epidermis development (GO:0045682) | 3.12419012 |
63 | atrioventricular valve morphogenesis (GO:0003181) | 3.11753383 |
64 | ribosomal large subunit biogenesis (GO:0042273) | 3.07729452 |
65 | hair follicle morphogenesis (GO:0031069) | 3.06936271 |
66 | negative regulation of epidermal growth factor-activated receptor activity (GO:0007175) | 3.05826179 |
67 | cytidine deamination (GO:0009972) | 3.02404936 |
68 | cytidine metabolic process (GO:0046087) | 3.02404936 |
69 | cytidine catabolic process (GO:0006216) | 3.02404936 |
70 | ventricular cardiac muscle cell action potential (GO:0086005) | 2.99657181 |
71 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 2.99368098 |
72 | lipoxygenase pathway (GO:0019372) | 2.95875439 |
73 | * keratinocyte development (GO:0003334) | 2.95675781 |
74 | cell-substrate adherens junction assembly (GO:0007045) | 2.95472668 |
75 | focal adhesion assembly (GO:0048041) | 2.95472668 |
76 | activation of Rac GTPase activity (GO:0032863) | 2.95310068 |
77 | * positive regulation of epidermis development (GO:0045684) | 2.95125075 |
78 | nucleobase biosynthetic process (GO:0046112) | 2.92772602 |
79 | negative regulation of T cell differentiation in thymus (GO:0033085) | 2.91173510 |
80 | eyelid development in camera-type eye (GO:0061029) | 2.89065866 |
81 | positive regulation of monocyte chemotaxis (GO:0090026) | 2.88578800 |
82 | renal filtration (GO:0097205) | 2.88180039 |
83 | wound healing, spreading of epidermal cells (GO:0035313) | 2.83686614 |
84 | adhesion of symbiont to host (GO:0044406) | 2.83580370 |
85 | L-serine transport (GO:0015825) | 2.83258324 |
86 | regulation of chemokine secretion (GO:0090196) | 2.81398366 |
87 | viral transcription (GO:0019083) | 2.80654101 |
88 | regulation of heart rate by cardiac conduction (GO:0086091) | 2.79288993 |
89 | negative regulation of epidermis development (GO:0045683) | 2.78547994 |
90 | translational initiation (GO:0006413) | 2.76425848 |
91 | endodermal cell differentiation (GO:0035987) | 2.76078177 |
92 | regulation of epidermal growth factor-activated receptor activity (GO:0007176) | 2.75742966 |
93 | mammary gland epithelial cell proliferation (GO:0033598) | 2.75032476 |
94 | negative regulation of interferon-gamma production (GO:0032689) | 2.74427680 |
95 | translational termination (GO:0006415) | 2.73848646 |
96 | protein neddylation (GO:0045116) | 2.73661322 |
97 | cell communication involved in cardiac conduction (GO:0086065) | 2.70242848 |
98 | positive regulation of T cell differentiation in thymus (GO:0033089) | 2.68734404 |
99 | regulation of endothelial cell chemotaxis (GO:2001026) | 2.67515429 |
100 | linoleic acid metabolic process (GO:0043651) | 2.65641393 |
101 | ribonucleoprotein complex biogenesis (GO:0022613) | 2.65334136 |
102 | morphogenesis of embryonic epithelium (GO:0016331) | 2.64877381 |
103 | mitotic G2 DNA damage checkpoint (GO:0007095) | 2.63432450 |
104 | regulation of hair cycle (GO:0042634) | 2.63420481 |
105 | negative regulation of stem cell proliferation (GO:2000647) | 2.63080329 |
106 | mitotic G1 DNA damage checkpoint (GO:0031571) | 2.61929697 |
107 | regulation of autophagic vacuole assembly (GO:2000785) | 2.61580970 |
108 | positive regulation of Cdc42 GTPase activity (GO:0043089) | 2.61008861 |
109 | phosphatidylserine acyl-chain remodeling (GO:0036150) | 2.60922598 |
110 | adherens junction organization (GO:0034332) | 2.59966628 |
111 | wound healing (GO:0042060) | 2.59865383 |
112 | regulation of translational termination (GO:0006449) | 2.58666740 |
113 | adherens junction assembly (GO:0034333) | 2.57962536 |
114 | folic acid transport (GO:0015884) | 2.57333200 |
115 | membrane tubulation (GO:0097320) | 2.56643791 |
116 | epithelial cell proliferation (GO:0050673) | 2.56222187 |
117 | cellular component disassembly involved in execution phase of apoptosis (GO:0006921) | 2.53489532 |
118 | COPI coating of Golgi vesicle (GO:0048205) | 2.53256059 |
119 | Golgi transport vesicle coating (GO:0048200) | 2.53256059 |
120 | cell-cell junction assembly (GO:0007043) | 2.52193710 |
121 | membrane raft organization (GO:0031579) | 2.50998708 |
122 | cell differentiation involved in embryonic placenta development (GO:0060706) | 2.50743803 |
123 | negative regulation of cell fate commitment (GO:0010454) | 2.49657510 |
124 | proteasome assembly (GO:0043248) | 2.49193116 |
125 | tight junction assembly (GO:0070830) | 2.48293469 |
126 | hair cycle process (GO:0022405) | 2.47413608 |
127 | molting cycle process (GO:0022404) | 2.47413608 |
128 | mitotic metaphase plate congression (GO:0007080) | 2.46984174 |
129 | negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665) | 2.46788703 |
130 | negative regulation of cartilage development (GO:0061037) | 2.46349042 |
131 | regulation of gene silencing by miRNA (GO:0060964) | 2.46001544 |
132 | regulation of gene silencing by RNA (GO:0060966) | 2.46001544 |
133 | regulation of posttranscriptional gene silencing (GO:0060147) | 2.46001544 |
134 | regulation of vitamin metabolic process (GO:0030656) | 2.45996565 |
135 | gland morphogenesis (GO:0022612) | 2.45675450 |
136 | cardiac right ventricle morphogenesis (GO:0003215) | 2.44084145 |
137 | branching involved in labyrinthine layer morphogenesis (GO:0060670) | 2.43676210 |
138 | ribosome biogenesis (GO:0042254) | 2.43326371 |
139 | blastocyst development (GO:0001824) | 2.41864786 |
140 | mesodermal cell differentiation (GO:0048333) | 2.40899208 |
141 | viral life cycle (GO:0019058) | 2.40710538 |
142 | chondrocyte proliferation (GO:0035988) | 2.40250775 |
143 | translational elongation (GO:0006414) | 2.38843105 |
144 | * regulation of epidermal cell differentiation (GO:0045604) | 2.38115793 |
145 | vitamin transmembrane transport (GO:0035461) | 2.36334082 |
146 | regulation of transforming growth factor beta2 production (GO:0032909) | 2.34841850 |
147 | regulation of G0 to G1 transition (GO:0070316) | 2.34088685 |
148 | negative regulation of epidermal cell differentiation (GO:0045605) | 2.33541921 |
149 | branching involved in mammary gland duct morphogenesis (GO:0060444) | 2.33179479 |
150 | hair cycle (GO:0042633) | 13.6145462 |
151 | molting cycle (GO:0042303) | 13.6145462 |
152 | hemidesmosome assembly (GO:0031581) | 12.0735508 |
153 | desmosome organization (GO:0002934) | 10.9612566 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 3.99795980 |
2 | ZNF263_19887448_ChIP-Seq_K562_Human | 2.66732372 |
3 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.66452975 |
4 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.62550574 |
5 | * SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 2.37386600 |
6 | E2F7_22180533_ChIP-Seq_HELA_Human | 2.29792195 |
7 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 2.27864683 |
8 | * P63_26484246_Chip-Seq_KERATINOCYTES_Human | 2.22438083 |
9 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.01866220 |
10 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 2.00780480 |
11 | * TP63_17297297_ChIP-ChIP_HaCaT_Human | 12.7635834 |
12 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.92080031 |
13 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.89309277 |
14 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.86705595 |
15 | * SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.82393746 |
16 | * SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.82393746 |
17 | * ATF3_27146783_Chip-Seq_COLON_Human | 1.79722700 |
18 | * KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.77265161 |
19 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.76413392 |
20 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.74380560 |
21 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.68534197 |
22 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 1.68379564 |
23 | * RACK7_27058665_Chip-Seq_MCF-7_Human | 1.68061973 |
24 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.65041100 |
25 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.63641043 |
26 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.58607564 |
27 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.57106695 |
28 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.55981342 |
29 | * KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.54484215 |
30 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.52272993 |
31 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.52272993 |
32 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.52272993 |
33 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.49311923 |
34 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.48636751 |
35 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.48449557 |
36 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.45569792 |
37 | * TP63_23658742_ChIP-Seq_EP156T_Human | 1.44467297 |
38 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.44172497 |
39 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.41250100 |
40 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.38220027 |
41 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.35417137 |
42 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.34490711 |
43 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.33319432 |
44 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 1.32764957 |
45 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 1.30906311 |
46 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.28932276 |
47 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.27155571 |
48 | * GATA6_25053715_ChIP-Seq_YYC3_Human | 1.26615057 |
49 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.24647617 |
50 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.23724931 |
51 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.22961259 |
52 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.21883895 |
53 | * NANOG_18692474_ChIP-Seq_MEFs_Mouse | 1.21455093 |
54 | EOMES_20176728_ChIP-ChIP_TSCs_Mouse | 1.20380821 |
55 | * ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.18074591 |
56 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.18020372 |
57 | * ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.16570901 |
58 | GATA4_25053715_ChIP-Seq_YYC3_Human | 1.13543445 |
59 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.11694467 |
60 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.10590716 |
61 | * TP63_22573176_ChIP-Seq_HFKS_Human | 1.10307903 |
62 | * OCT4_18692474_ChIP-Seq_MEFs_Mouse | 1.10003264 |
63 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 1.09218983 |
64 | * SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 1.07514656 |
65 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 1.06815888 |
66 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.06806968 |
67 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.06230487 |
68 | * KLF5_25053715_ChIP-Seq_YYC3_Human | 1.05238853 |
69 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.04713577 |
70 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.04278704 |
71 | * UBF1/2_26484160_Chip-Seq_HMECs_Human | 1.04277381 |
72 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.04173268 |
73 | * JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.03427607 |
74 | GATA3_24758297_ChIP-Seq_MCF-7_Human | 1.03221616 |
75 | * XRN2_22483619_ChIP-Seq_HELA_Human | 1.02786040 |
76 | P68_20966046_ChIP-Seq_HELA_Human | 1.01451115 |
77 | CTCF_20526341_ChIP-Seq_ESCs_Human | 1.01370843 |
78 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.00997131 |
79 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.99182810 |
80 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 0.99181335 |
81 | * BCOR_27268052_Chip-Seq_Bcells_Human | 0.99082277 |
82 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 0.98933153 |
83 | * HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.98577297 |
84 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 0.98366780 |
85 | * E2F1_20622854_ChIP-Seq_HELA_Human | 0.97809740 |
86 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.97662479 |
87 | TP53_22127205_ChIP-Seq_IMR90_Human | 0.97035799 |
88 | SOX2_20726797_ChIP-Seq_SW620_Human | 0.96624647 |
89 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 0.95756562 |
90 | TCF3_18692474_ChIP-Seq_MESCs_Mouse | 0.95484373 |
91 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 0.91921028 |
92 | CLOCK_20551151_ChIP-Seq_293T_Human | 0.91813642 |
93 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.91687445 |
94 | * JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.91605765 |
95 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.90634536 |
96 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.89854194 |
97 | * SA1_27219007_Chip-Seq_ERYTHROID_Human | 0.89265708 |
98 | CJUN_26792858_Chip-Seq_BT549_Human | 0.87832822 |
99 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 0.86225142 |
100 | PHF8_20622854_ChIP-Seq_HELA_Human | 0.86033984 |
101 | * CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 0.85674510 |
102 | SMC4_20622854_ChIP-Seq_HELA_Human | 0.85251543 |
103 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 0.84703797 |
104 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 0.84136558 |
105 | NANOG_18347094_ChIP-ChIP_MESCs_Mouse | 0.83818700 |
106 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.83085409 |
107 | * NANOG_18692474_ChIP-Seq_MESCs_Mouse | 0.83054804 |
108 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.82746308 |
109 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.82074998 |
110 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 0.81549323 |
111 | * CTCF_27219007_Chip-Seq_Bcells_Human | 0.81390502 |
112 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.80726592 |
113 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 0.79073360 |
114 | * P300_27058665_Chip-Seq_ZR-75-30cells_Human | 0.78666078 |
115 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.78627225 |
116 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.78492477 |
117 | * CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 0.78273355 |
118 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.77812622 |
119 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.75232875 |
120 | GATA3_20176728_ChIP-ChIP_TSCs_Mouse | 0.75100889 |
121 | * TCF4_18268006_ChIP-ChIP_LS174T_Human | 0.73766647 |
122 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.73274496 |
123 | * KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 0.72854512 |
124 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 0.72444097 |
125 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 0.72444097 |
126 | * KDM2B_26808549_Chip-Seq_SUP-B15_Human | 0.71419963 |
127 | TP53_18474530_ChIP-ChIP_U2OS_Human | 0.70744350 |
128 | P63_20808887_ChIP-Seq_KERATINOCYTES_Human | 0.67123657 |
129 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 0.66674491 |
130 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 0.66563478 |
131 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.66120220 |
132 | CREB1_26743006_Chip-Seq_LNCaP_Human | 0.64453220 |
133 | * KDM2B_26808549_Chip-Seq_K562_Human | 0.63207296 |
134 | * CHD1_26751641_Chip-Seq_LNCaP_Human | 0.61995829 |
135 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.61626972 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0010234_abnormal_vibrissa_follicle | 6.25729360 |
2 | MP0002796_impaired_skin_barrier | 5.80597825 |
3 | MP0000579_abnormal_nail_morphology | 5.16705243 |
4 | MP0005275_abnormal_skin_tensile | 4.03729680 |
5 | MP0005501_abnormal_skin_physiology | 3.71592761 |
6 | MP0002098_abnormal_vibrissa_morphology | 3.68973743 |
7 | MP0000383_abnormal_hair_follicle | 3.64054231 |
8 | MP0010678_abnormal_skin_adnexa | 3.54508130 |
9 | MP0002254_reproductive_system_inflammat | 3.41058355 |
10 | MP0003941_abnormal_skin_development | 3.23228423 |
11 | * MP0001216_abnormal_epidermal_layer | 2.94712888 |
12 | MP0000647_abnormal_sebaceous_gland | 2.94260083 |
13 | MP0000467_abnormal_esophagus_morphology | 2.93169544 |
14 | MP0003705_abnormal_hypodermis_morpholog | 2.91993183 |
15 | MP0003453_abnormal_keratinocyte_physiol | 2.76889202 |
16 | MP0002060_abnormal_skin_morphology | 2.64494818 |
17 | MP0004381_abnormal_hair_follicle | 2.45872328 |
18 | * MP0000377_abnormal_hair_follicle | 2.42342744 |
19 | * MP0000762_abnormal_tongue_morphology | 2.23050937 |
20 | MP0010771_integument_phenotype | 2.21361360 |
21 | MP0004947_skin_inflammation | 2.17733573 |
22 | MP0003693_abnormal_embryo_hatching | 2.09711597 |
23 | MP0000427_abnormal_hair_cycle | 2.06177067 |
24 | MP0001849_ear_inflammation | 1.85439745 |
25 | MP0010352_gastrointestinal_tract_polyps | 1.81147456 |
26 | * MP0003566_abnormal_cell_adhesion | 1.76354838 |
27 | MP0003283_abnormal_digestive_organ | 1.65283946 |
28 | MP0000678_abnormal_parathyroid_gland | 1.58644871 |
29 | MP0004264_abnormal_extraembryonic_tissu | 1.56373423 |
30 | MP0004957_abnormal_blastocyst_morpholog | 1.54077732 |
31 | * MP0009931_abnormal_skin_appearance | 1.43171000 |
32 | * MP0000367_abnormal_coat/_hair | 1.41476164 |
33 | MP0000462_abnormal_digestive_system | 1.35773506 |
34 | MP0004782_abnormal_surfactant_physiolog | 1.34710738 |
35 | MP0010030_abnormal_orbit_morphology | 1.32994807 |
36 | MP0002877_abnormal_melanocyte_morpholog | 1.31790822 |
37 | MP0001243_abnormal_dermal_layer | 1.31715046 |
38 | MP0009379_abnormal_foot_pigmentation | 1.29454086 |
39 | MP0005023_abnormal_wound_healing | 1.23743893 |
40 | MP0003878_abnormal_ear_physiology | 1.22023802 |
41 | MP0005377_hearing/vestibular/ear_phenot | 1.22023802 |
42 | MP0000537_abnormal_urethra_morphology | 1.22015952 |
43 | MP0003111_abnormal_nucleus_morphology | 1.21425828 |
44 | MP0004185_abnormal_adipocyte_glucose | 1.18424706 |
45 | MP0001346_abnormal_lacrimal_gland | 1.16266753 |
46 | MP0005451_abnormal_body_composition | 1.16156889 |
47 | * MP0001191_abnormal_skin_condition | 1.12718038 |
48 | MP0000566_synostosis | 1.09117937 |
49 | MP0004885_abnormal_endolymph | 1.05086459 |
50 | MP0008789_abnormal_olfactory_epithelium | 1.02514311 |
51 | MP0004019_abnormal_vitamin_homeostasis | 0.95749721 |
52 | MP0005076_abnormal_cell_differentiation | 0.94345266 |
53 | MP0003718_maternal_effect | 0.94323299 |
54 | * MP0000627_abnormal_mammary_gland | 0.85505486 |
55 | MP0001851_eye_inflammation | 0.84350027 |
56 | * MP0003755_abnormal_palate_morphology | 0.83798469 |
57 | MP0005257_abnormal_intraocular_pressure | 0.83484249 |
58 | MP0002282_abnormal_trachea_morphology | 0.83175306 |
59 | MP0004272_abnormal_basement_membrane | 0.82538655 |
60 | MP0009840_abnormal_foam_cell | 0.82097589 |
61 | * MP0002111_abnormal_tail_morphology | 0.81424599 |
62 | MP0001730_embryonic_growth_arrest | 0.80690905 |
63 | MP0000858_altered_metastatic_potential | 0.79930604 |
64 | MP0009780_abnormal_chondrocyte_physiolo | 0.77095861 |
65 | MP0008932_abnormal_embryonic_tissue | 0.76999511 |
66 | MP0005360_urolithiasis | 0.73591000 |
67 | MP0000516_abnormal_urinary_system | 0.73005666 |
68 | MP0005367_renal/urinary_system_phenotyp | 0.73005666 |
69 | MP0003077_abnormal_cell_cycle | 0.69628590 |
70 | MP0005394_taste/olfaction_phenotype | 0.68365382 |
71 | MP0005499_abnormal_olfactory_system | 0.68365382 |
72 | MP0000750_abnormal_muscle_regeneration | 0.65958813 |
73 | MP0008007_abnormal_cellular_replicative | 0.65832976 |
74 | * MP0000350_abnormal_cell_proliferation | 0.65628164 |
75 | MP0000465_gastrointestinal_hemorrhage | 0.64533003 |
76 | MP0000613_abnormal_salivary_gland | 0.63894001 |
77 | MP0004197_abnormal_fetal_growth/weight/ | 0.63582982 |
78 | MP0003786_premature_aging | 0.63363018 |
79 | MP0000538_abnormal_urinary_bladder | 0.63324771 |
80 | MP0003806_abnormal_nucleotide_metabolis | 0.63074635 |
81 | MP0002095_abnormal_skin_pigmentation | 0.62185313 |
82 | * MP0001340_abnormal_eyelid_morphology | 0.60997491 |
83 | MP0008260_abnormal_autophagy | 0.60594571 |
84 | MP0001542_abnormal_bone_strength | 0.59977620 |
85 | MP0003866_abnormal_defecation | 0.59209397 |
86 | MP0005508_abnormal_skeleton_morphology | 0.59102098 |
87 | MP0000470_abnormal_stomach_morphology | 0.57958915 |
88 | MP0002086_abnormal_extraembryonic_tissu | 0.57380512 |
89 | MP0010094_abnormal_chromosome_stability | 0.57032620 |
90 | MP0001188_hyperpigmentation | 0.56530804 |
91 | * MP0000477_abnormal_intestine_morphology | 0.56296833 |
92 | MP0001784_abnormal_fluid_regulation | 0.55395797 |
93 | MP0002089_abnormal_postnatal_growth/wei | 0.54788790 |
94 | MP0003950_abnormal_plasma_membrane | 0.54358922 |
95 | MP0000490_abnormal_crypts_of | 0.53637533 |
96 | MP0001756_abnormal_urination | 0.53286488 |
97 | MP0003191_abnormal_cellular_cholesterol | 0.51458981 |
98 | MP0005380_embryogenesis_phenotype | 0.50893129 |
99 | MP0001672_abnormal_embryogenesis/_devel | 0.50893129 |
100 | MP0000003_abnormal_adipose_tissue | 0.50699184 |
101 | * MP0003937_abnormal_limbs/digits/tail_de | 0.50440723 |
102 | MP0005193_abnormal_anterior_eye | 0.49740775 |
103 | * MP0000432_abnormal_head_morphology | 0.49633648 |
104 | MP0005409_darkened_coat_color | 0.49339958 |
105 | * MP0002084_abnormal_developmental_patter | 0.46494842 |
106 | MP0010155_abnormal_intestine_physiology | 0.46264770 |
107 | * MP0002234_abnormal_pharynx_morphology | 0.46180828 |
108 | MP0002896_abnormal_bone_mineralization | 0.45923981 |
109 | MP0003045_fibrosis | 0.44243642 |
110 | MP0000733_abnormal_muscle_development | 0.44142565 |
111 | MP0000428_abnormal_craniofacial_morphol | 0.43488267 |
112 | * MP0009053_abnormal_anal_canal | 0.42982456 |
113 | MP0001299_abnormal_eye_distance/ | 0.42356980 |
114 | MP0005197_abnormal_uvea_morphology | 0.42146635 |
115 | MP0002088_abnormal_embryonic_growth/wei | 0.42092980 |
116 | * MP0002085_abnormal_embryonic_tissue | 0.41974750 |
117 | MP0003119_abnormal_digestive_system | 0.41697449 |
118 | MP0003091_abnormal_cell_migration | 0.41477750 |
119 | MP0003385_abnormal_body_wall | 0.41299095 |
120 | MP0001697_abnormal_embryo_size | 0.41190099 |
121 | MP0003984_embryonic_growth_retardation | 0.41072287 |
122 | MP0003329_amyloid_beta_deposits | 0.40515579 |
123 | MP0005375_adipose_tissue_phenotype | 0.39736819 |
124 | MP0005248_abnormal_Harderian_gland | 0.39543707 |
125 | MP0003638_abnormal_response/metabolism_ | 0.36639568 |
126 | MP0004043_abnormal_pH_regulation | 0.35854680 |
127 | * MP0002177_abnormal_outer_ear | 0.35497160 |
128 | MP0004858_abnormal_nervous_system | 0.34640362 |
129 | MP0001765_abnormal_ion_homeostasis | 0.33899854 |
130 | MP0005666_abnormal_adipose_tissue | 0.31688121 |
131 | MP0005083_abnormal_biliary_tract | 0.30410571 |
132 | MP0005075_abnormal_melanosome_morpholog | 0.30015432 |
133 | * MP0005621_abnormal_cell_physiology | 0.27167259 |
134 | MP0000013_abnormal_adipose_tissue | 0.26763264 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Fragile nails (HP:0001808) | 7.64543701 |
2 | Milia (HP:0001056) | 7.14757021 |
3 | Abnormality of nail color (HP:0100643) | 7.07429563 |
4 | Onycholysis (HP:0001806) | 6.61146895 |
5 | Plantar hyperkeratosis (HP:0007556) | 6.49212967 |
6 | Hypotrichosis (HP:0001006) | 6.38484037 |
7 | Pili torti (HP:0003777) | 6.21463936 |
8 | Thick nail (HP:0001805) | 6.18371394 |
9 | Woolly hair (HP:0002224) | 6.10137121 |
10 | Nail dystrophy (HP:0008404) | 5.50880742 |
11 | Palmoplantar hyperkeratosis (HP:0000972) | 5.37671201 |
12 | Palmar hyperkeratosis (HP:0010765) | 5.15771480 |
13 | Alopecia of scalp (HP:0002293) | 5.14331066 |
14 | Right ventricular cardiomyopathy (HP:0011663) | 4.68313022 |
15 | Ridged nail (HP:0001807) | 4.57976025 |
16 | Atrophic scars (HP:0001075) | 4.32272629 |
17 | Abnormal blistering of the skin (HP:0008066) | 4.17791074 |
18 | Oral leukoplakia (HP:0002745) | 4.02522400 |
19 | Increased IgE level (HP:0003212) | 4.02506502 |
20 | Congenital ichthyosiform erythroderma (HP:0007431) | 3.71437545 |
21 | Sparse eyelashes (HP:0000653) | 3.51179321 |
22 | Abnormal hair laboratory examination (HP:0003328) | 3.50833250 |
23 | Abnormality of the axillary hair (HP:0100134) | 3.40007620 |
24 | Abnormality of secondary sexual hair (HP:0009888) | 3.40007620 |
25 | Erythroderma (HP:0001019) | 3.27548371 |
26 | Abnormality of the salivary glands (HP:0010286) | 3.10777397 |
27 | Abnormality of placental membranes (HP:0011409) | 3.06038277 |
28 | Amniotic constriction ring (HP:0009775) | 3.06038277 |
29 | Blepharitis (HP:0000498) | 3.02538019 |
30 | Erythema (HP:0010783) | 2.97604995 |
31 | Pterygium (HP:0001059) | 2.95534133 |
32 | Follicular hyperkeratosis (HP:0007502) | 2.92402911 |
33 | Posterior subcapsular cataract (HP:0007787) | 2.86199832 |
34 | Breast hypoplasia (HP:0003187) | 2.83808766 |
35 | Popliteal pterygium (HP:0009756) | 2.81303041 |
36 | Brittle hair (HP:0002299) | 2.75319125 |
37 | Hypoplastic labia majora (HP:0000059) | 2.68154801 |
38 | Anonychia (HP:0001798) | 2.67691900 |
39 | Natal tooth (HP:0000695) | 2.62271088 |
40 | Dry hair (HP:0011359) | 2.60719319 |
41 | Fatigable weakness (HP:0003473) | 2.53106782 |
42 | Abnormality of the neuromuscular junction (HP:0003398) | 2.53106782 |
43 | Lip pit (HP:0100267) | 2.51874033 |
44 | Aplasia cutis congenita (HP:0001057) | 2.51115689 |
45 | Slow-growing hair (HP:0002217) | 2.49713569 |
46 | Abnormality of hair growth rate (HP:0011363) | 2.49713569 |
47 | Ankyloglossia (HP:0010296) | 2.48747638 |
48 | Oligodontia (HP:0000677) | 2.48499672 |
49 | Curly hair (HP:0002212) | 2.47416939 |
50 | Breech presentation (HP:0001623) | 2.46095896 |
51 | Flat acetabular roof (HP:0003180) | 2.43120259 |
52 | Abnormality of the labia majora (HP:0012881) | 2.41906116 |
53 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 2.41845680 |
54 | Neonatal short-limb short stature (HP:0008921) | 2.38112601 |
55 | Symphalangism affecting the phalanges of the hand (HP:0009773) | 2.37502992 |
56 | Palmoplantar keratoderma (HP:0000982) | 2.34533201 |
57 | Ectropion (HP:0000656) | 2.32587609 |
58 | Esophageal atresia (HP:0002032) | 2.27848283 |
59 | Hypohidrosis (HP:0000966) | 2.26968038 |
60 | Trismus (HP:0000211) | 2.25837560 |
61 | Flat capital femoral epiphysis (HP:0003370) | 2.24839342 |
62 | Irregular epiphyses (HP:0010582) | 2.23523705 |
63 | Concave nail (HP:0001598) | 2.22706435 |
64 | Advanced eruption of teeth (HP:0006288) | 2.20786165 |
65 | Down-sloping shoulders (HP:0200021) | 2.20354095 |
66 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 2.20060815 |
67 | Fragile skin (HP:0001030) | 2.14150655 |
68 | Ventricular tachycardia (HP:0004756) | 2.11602985 |
69 | Parakeratosis (HP:0001036) | 2.06266959 |
70 | Absent hair (HP:0002298) | 2.05332339 |
71 | Abnormality of the fingernails (HP:0001231) | 2.05326040 |
72 | Abnormality of the distal phalanges of the toes (HP:0010182) | 2.04292685 |
73 | Amelogenesis imperfecta (HP:0000705) | 2.04205393 |
74 | Corneal erosion (HP:0200020) | 2.04017414 |
75 | Axonal loss (HP:0003447) | 2.03841972 |
76 | Hypoplasia of dental enamel (HP:0006297) | 2.01567612 |
77 | Multifactorial inheritance (HP:0001426) | 2.01563190 |
78 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 2.00507964 |
79 | Congenital, generalized hypertrichosis (HP:0004540) | 2.00009829 |
80 | Abnormality of oral frenula (HP:0000190) | 1.98436619 |
81 | Hyperhidrosis (HP:0000975) | 1.98350617 |
82 | Absent phalangeal crease (HP:0006109) | 1.97184057 |
83 | Dehydration (HP:0001944) | 1.96656161 |
84 | Selective tooth agenesis (HP:0001592) | 1.95456274 |
85 | Distal lower limb muscle weakness (HP:0009053) | 1.95281364 |
86 | Sparse scalp hair (HP:0002209) | 1.91172672 |
87 | Corneal dystrophy (HP:0001131) | 1.90857576 |
88 | Ventricular fibrillation (HP:0001663) | 1.88428684 |
89 | Septate vagina (HP:0001153) | 1.88110745 |
90 | Pustule (HP:0200039) | 1.84237733 |
91 | Hypodontia (HP:0000668) | 1.82367418 |
92 | Abnormality of the 1st metacarpal (HP:0010009) | 1.82002534 |
93 | Increased connective tissue (HP:0009025) | 1.81911725 |
94 | Xerostomia (HP:0000217) | 1.79143886 |
95 | Autoamputation (HP:0001218) | 1.76524526 |
96 | Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173) | 1.76401155 |
97 | Subcapsular cataract (HP:0000523) | 1.74416556 |
98 | Rough bone trabeculation (HP:0100670) | 1.73668776 |
99 | Carious teeth (HP:0000670) | 1.73012833 |
100 | Spinal cord compression (HP:0002176) | 1.72935554 |
101 | Nasolacrimal duct obstruction (HP:0000579) | 1.72263364 |
102 | Abnormal vertebral ossification (HP:0100569) | 1.72034618 |
103 | Abnormality of permanent molar morphology (HP:0011071) | 1.70185681 |
104 | Abnormality of the dental root (HP:0006486) | 1.70185681 |
105 | Taurodontia (HP:0000679) | 1.70185681 |
106 | Acanthosis nigricans (HP:0000956) | 1.69319545 |
107 | Epidermoid cyst (HP:0200040) | 1.68975847 |
108 | Skin ulcer (HP:0200042) | 1.67652855 |
109 | Squamous cell carcinoma (HP:0002860) | 1.67568411 |
110 | Muscle fiber splitting (HP:0003555) | 1.64917425 |
111 | Myopathic facies (HP:0002058) | 1.64823328 |
112 | Short phalanx of the thumb (HP:0009660) | 1.64778069 |
113 | Premature rupture of membranes (HP:0001788) | 1.63667371 |
114 | Split foot (HP:0001839) | 1.63608263 |
115 | Carpal bone hypoplasia (HP:0001498) | 1.63358135 |
116 | Neonatal onset (HP:0003623) | 1.63072101 |
117 | Cheilitis (HP:0100825) | 1.62938193 |
118 | Abnormality of the middle phalanges of the toes (HP:0010183) | 1.62889427 |
119 | Cupped ribs (HP:0000887) | 1.62384061 |
120 | Abnormality of the 2nd finger (HP:0004100) | 1.62316947 |
121 | Short middle phalanx of finger (HP:0005819) | 1.60942031 |
122 | Laryngomalacia (HP:0001601) | 1.59803905 |
123 | Labial hypoplasia (HP:0000066) | 1.58361816 |
124 | Abnormality of the umbilical cord (HP:0010881) | 1.57930581 |
125 | Areflexia of lower limbs (HP:0002522) | 1.57773287 |
126 | Absent eyelashes (HP:0000561) | 1.57071894 |
127 | Biliary tract neoplasm (HP:0100574) | 1.56808755 |
128 | Abnormal finger flexion creases (HP:0006143) | 1.56236086 |
129 | Abnormality of the gastric mucosa (HP:0004295) | 1.55643608 |
130 | Abnormality of molar (HP:0011077) | 1.55109982 |
131 | Abnormality of molar morphology (HP:0011070) | 1.55109982 |
132 | Conjunctival hamartoma (HP:0100780) | 1.55054870 |
133 | Short nail (HP:0001799) | 1.54451435 |
134 | Vertebral clefting (HP:0008428) | 1.53946096 |
135 | Stillbirth (HP:0003826) | 1.53058822 |
136 | Hypoplastic female external genitalia (HP:0012815) | 1.50776957 |
137 | Abnormality of the dental pulp (HP:0006479) | 1.45576161 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EPHA2 | 6.87361181 |
2 | TAOK3 | 6.26280873 |
3 | EPHB2 | 3.56772709 |
4 | MAP3K3 | 3.12473021 |
5 | MST1R | 2.86977759 |
6 | BUB1 | 2.84979921 |
7 | SIK1 | 2.69807773 |
8 | TSSK6 | 2.52683647 |
9 | WEE1 | 2.41431787 |
10 | NME1 | 2.24471349 |
11 | TGFBR1 | 2.19723816 |
12 | RPS6KB2 | 2.17802772 |
13 | TAOK1 | 2.13417172 |
14 | NTRK1 | 2.07179470 |
15 | MAPKAPK3 | 1.93376577 |
16 | FER | 1.92459150 |
17 | MAP2K2 | 1.86591995 |
18 | RIPK1 | 1.86424628 |
19 | MAP3K6 | 1.86408747 |
20 | MST4 | 1.85380599 |
21 | SMG1 | 1.81061807 |
22 | LATS1 | 1.69216824 |
23 | NEK1 | 1.59251013 |
24 | PIM2 | 1.58870132 |
25 | LMTK2 | 1.50608666 |
26 | MAP3K2 | 1.48044842 |
27 | ZAK | 1.39988621 |
28 | PDGFRA | 1.38312680 |
29 | RPS6KA4 | 1.38066692 |
30 | MAP3K12 | 1.34820722 |
31 | FLT3 | 1.32454401 |
32 | PBK | 1.30759617 |
33 | PRKCI | 1.27156397 |
34 | TTK | 1.23446917 |
35 | STK10 | 1.18681424 |
36 | MET | 1.17709222 |
37 | STK38L | 1.15011649 |
38 | MAP3K11 | 1.14846548 |
39 | LATS2 | 1.13581808 |
40 | MAP3K8 | 1.09312040 |
41 | PLK4 | 1.08498244 |
42 | EPHA3 | 1.06715557 |
43 | AURKB | 1.06664068 |
44 | AKT3 | 1.04427745 |
45 | EPHB1 | 1.00590884 |
46 | KSR2 | 0.99786398 |
47 | PTK2 | 0.98609740 |
48 | TRIB3 | 0.97324537 |
49 | PIK3CA | 0.91826222 |
50 | EEF2K | 0.88360060 |
51 | ALK | 0.84000597 |
52 | TRPM7 | 0.82690838 |
53 | FGFR4 | 0.81761181 |
54 | TESK1 | 0.80687274 |
55 | MAP3K9 | 0.78688869 |
56 | PAK4 | 0.78624255 |
57 | PLK1 | 0.78049999 |
58 | ERN1 | 0.77413020 |
59 | TTN | 0.77254409 |
60 | PTK6 | 0.72340892 |
61 | STK24 | 0.72159325 |
62 | NEK2 | 0.72106121 |
63 | LRRK2 | 0.70804313 |
64 | MAP2K1 | 0.70331232 |
65 | ILK | 0.67904354 |
66 | PLK3 | 0.67595642 |
67 | PRPF4B | 0.66533846 |
68 | STK38 | 0.63082204 |
69 | FGFR1 | 0.62723107 |
70 | PRKD2 | 0.62373478 |
71 | MAPKAPK2 | 0.61818131 |
72 | PKN2 | 0.61448242 |
73 | PNCK | 0.61420480 |
74 | TESK2 | 0.60009127 |
75 | STK3 | 0.59854132 |
76 | PIK3CG | 0.59466896 |
77 | CDK7 | 0.59324783 |
78 | TGFBR2 | 0.58305001 |
79 | CDK6 | 0.58089627 |
80 | DYRK3 | 0.57109871 |
81 | RPS6KA2 | 0.56861642 |
82 | MAP3K13 | 0.56746860 |
83 | RAF1 | 0.56036586 |
84 | ERBB4 | 0.55653671 |
85 | ABL2 | 0.54415365 |
86 | PDK2 | 0.53722050 |
87 | NME2 | 0.52413579 |
88 | MAP3K1 | 0.52169119 |
89 | MTOR | 0.51446134 |
90 | MAP2K3 | 0.49099840 |
91 | MOS | 0.48156176 |
92 | PAK1 | 0.47793512 |
93 | CDK12 | 0.46422855 |
94 | ROCK2 | 0.46403642 |
95 | SIK3 | 0.45583475 |
96 | GRK6 | 0.45525440 |
97 | DDR2 | 0.44681692 |
98 | ARAF | 0.44437486 |
99 | AURKA | 0.44328783 |
100 | RPS6KA1 | 0.43309412 |
101 | PDGFRB | 0.42937347 |
102 | ERBB2 | 0.40465968 |
103 | SRPK1 | 0.39905039 |
104 | NEK6 | 0.39792968 |
105 | CSNK1E | 0.38931212 |
106 | MAP2K6 | 0.37951301 |
107 | NLK | 0.33944764 |
108 | BRSK2 | 0.32875112 |
109 | RET | 0.32519818 |
110 | IKBKB | 0.32194127 |
111 | GSK3A | 0.32140689 |
112 | KSR1 | 0.31919143 |
113 | EIF2AK1 | 0.31457443 |
114 | CDC42BPA | 0.30733759 |
115 | ICK | 0.30447849 |
116 | SGK223 | 0.30247979 |
117 | SGK494 | 0.30247979 |
118 | DMPK | 0.29230439 |
119 | DYRK2 | 0.28988084 |
120 | BRAF | 0.27807808 |
121 | PIM1 | 0.25941640 |
122 | IRAK3 | 0.24465859 |
123 | MELK | 0.23893805 |
124 | BMX | 0.23218470 |
125 | JAK3 | 0.22896056 |
126 | CHUK | 0.22760161 |
127 | CHEK1 | 0.22622303 |
128 | CDK4 | 0.22310008 |
129 | AKT2 | 0.20328953 |
130 | TAOK2 | 0.20069824 |
131 | PRKG2 | 0.19389678 |
132 | PAK2 | 0.19317641 |
133 | MAPKAPK5 | 0.19083832 |
134 | RPS6KB1 | 0.18582403 |
135 | CDK9 | 0.18437810 |
136 | ADRBK1 | 0.18045649 |
137 | RPS6KC1 | 0.17480544 |
138 | RPS6KL1 | 0.17480544 |
139 | MKNK1 | 0.16887502 |
140 | CAMK2G | 0.16166421 |
141 | CSNK2A1 | 0.15920658 |
142 | TYK2 | 0.15715662 |
143 | ROCK1 | 0.15448020 |
144 | PRKCD | 0.14502861 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Proteasome_Homo sapiens_hsa03050 | 3.22825988 |
2 | RNA polymerase_Homo sapiens_hsa03020 | 3.10911885 |
3 | Ribosome_Homo sapiens_hsa03010 | 2.99736919 |
4 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.86354943 |
5 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 2.43136671 |
6 | Basal cell carcinoma_Homo sapiens_hsa05217 | 2.20612586 |
7 | RNA transport_Homo sapiens_hsa03013 | 2.12849035 |
8 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.93920163 |
9 | Tight junction_Homo sapiens_hsa04530 | 1.92349934 |
10 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.87963253 |
11 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.86109643 |
12 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.68185786 |
13 | Mineral absorption_Homo sapiens_hsa04978 | 1.67529603 |
14 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.65359691 |
15 | ECM-receptor interaction_Homo sapiens_hsa04512 | 1.64230061 |
16 | * p53 signaling pathway_Homo sapiens_hsa04115 | 1.64134935 |
17 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.62581496 |
18 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 1.61684502 |
19 | ErbB signaling pathway_Homo sapiens_hsa04012 | 1.61672355 |
20 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.59554834 |
21 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.59363529 |
22 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.55965871 |
23 | Adherens junction_Homo sapiens_hsa04520 | 1.53616695 |
24 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.51445485 |
25 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.50861567 |
26 | Spliceosome_Homo sapiens_hsa03040 | 1.50087775 |
27 | GnRH signaling pathway_Homo sapiens_hsa04912 | 1.46219128 |
28 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.45904559 |
29 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.43932356 |
30 | Bladder cancer_Homo sapiens_hsa05219 | 1.42508189 |
31 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.41569068 |
32 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.41510699 |
33 | Axon guidance_Homo sapiens_hsa04360 | 1.31866584 |
34 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.31699426 |
35 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.28728016 |
36 | * Cell cycle_Homo sapiens_hsa04110 | 1.28126480 |
37 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.27194078 |
38 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 1.27009412 |
39 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.26383211 |
40 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.23969344 |
41 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.22076067 |
42 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 1.20429779 |
43 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.19751953 |
44 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.19269245 |
45 | Glioma_Homo sapiens_hsa05214 | 1.18925020 |
46 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.18628949 |
47 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.18444126 |
48 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.15206034 |
49 | Thyroid cancer_Homo sapiens_hsa05216 | 1.15061635 |
50 | DNA replication_Homo sapiens_hsa03030 | 1.10351963 |
51 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.08638876 |
52 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.07968651 |
53 | Apoptosis_Homo sapiens_hsa04210 | 1.04977760 |
54 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.04250797 |
55 | Prion diseases_Homo sapiens_hsa05020 | 1.03211663 |
56 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.01543661 |
57 | Insulin signaling pathway_Homo sapiens_hsa04910 | 1.00983685 |
58 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.00195841 |
59 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.99032679 |
60 | Salmonella infection_Homo sapiens_hsa05132 | 0.98846627 |
61 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.98703923 |
62 | Sulfur relay system_Homo sapiens_hsa04122 | 0.98410419 |
63 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.97393115 |
64 | Amoebiasis_Homo sapiens_hsa05146 | 0.94478934 |
65 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.92275649 |
66 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.91454462 |
67 | Hepatitis C_Homo sapiens_hsa05160 | 0.86142330 |
68 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.85966649 |
69 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.85490048 |
70 | HTLV-I infection_Homo sapiens_hsa05166 | 0.82164303 |
71 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.81385284 |
72 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.81036935 |
73 | Mismatch repair_Homo sapiens_hsa03430 | 0.79841154 |
74 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.78904856 |
75 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.78462013 |
76 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.78206192 |
77 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.78089991 |
78 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.77468055 |
79 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.77050128 |
80 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.75722507 |
81 | Pathways in cancer_Homo sapiens_hsa05200 | 0.74438048 |
82 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.71341796 |
83 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.70961119 |
84 | Endometrial cancer_Homo sapiens_hsa05213 | 0.70276763 |
85 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.69953765 |
86 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.68812651 |
87 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.68735232 |
88 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.68595336 |
89 | Focal adhesion_Homo sapiens_hsa04510 | 0.68231839 |
90 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.67473030 |
91 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.67471289 |
92 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.66150699 |
93 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.65244447 |
94 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.64080342 |
95 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.63992057 |
96 | Base excision repair_Homo sapiens_hsa03410 | 0.63776860 |
97 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.62706244 |
98 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.61842849 |
99 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.61220768 |
100 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.60143927 |
101 | Renin secretion_Homo sapiens_hsa04924 | 0.58347472 |
102 | Long-term depression_Homo sapiens_hsa04730 | 0.58019828 |
103 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.56701879 |
104 | Legionellosis_Homo sapiens_hsa05134 | 0.56605326 |
105 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.56502420 |
106 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.55955524 |
107 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.55045128 |
108 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.53802332 |
109 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.53343765 |
110 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.52872175 |
111 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.52410464 |
112 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.50734855 |
113 | Histidine metabolism_Homo sapiens_hsa00340 | 0.50573862 |
114 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.49482830 |
115 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.49100853 |
116 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.49089097 |
117 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.47722716 |
118 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.47644863 |
119 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.46183239 |
120 | Galactose metabolism_Homo sapiens_hsa00052 | 0.45950794 |
121 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.45720911 |
122 | Shigellosis_Homo sapiens_hsa05131 | 0.45544197 |
123 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.45263598 |
124 | Purine metabolism_Homo sapiens_hsa00230 | 0.44941019 |
125 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.44886287 |
126 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.44787460 |
127 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.44566502 |
128 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.44005721 |
129 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.43376396 |
130 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.42662474 |
131 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.42125367 |
132 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.41968782 |
133 | Prostate cancer_Homo sapiens_hsa05215 | 0.41877341 |
134 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.41668416 |
135 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.41562021 |
136 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.41019410 |
137 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.40703943 |
138 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.40678749 |
139 | Pertussis_Homo sapiens_hsa05133 | 0.40090853 |
140 | Influenza A_Homo sapiens_hsa05164 | 0.39584192 |
141 | Melanogenesis_Homo sapiens_hsa04916 | 0.39474712 |
142 | Melanoma_Homo sapiens_hsa05218 | 0.37845583 |
143 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.37142439 |
144 | Homologous recombination_Homo sapiens_hsa03440 | 0.31691143 |
145 | Endocytosis_Homo sapiens_hsa04144 | 0.31203975 |
146 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.30729314 |
147 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.29277127 |