SGF29

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: CCDC101 is a subunit of 2 histone acetyltransferase complexes: the ADA2A (TADA2A; MIM 602276)-containing (ATAC) complex and the SPT3 (SUPT3H; MIM 602947)-TAF9 (MIM 600822)-GCN5 (KAT2A; MIM 602301)/PCAF (KAT2B; MIM 602303) acetylase (STAGA) complex. Both of these complexes contain either GCN5 or PCAF, which are paralogous acetyltransferases (Wang et al., 2008 [PubMed 18838386]). NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)6.21847323
2DNA deamination (GO:0045006)5.86253536
3maturation of SSU-rRNA (GO:0030490)5.23374803
4telomere maintenance via semi-conservative replication (GO:0032201)4.96673451
5DNA strand elongation involved in DNA replication (GO:0006271)4.83587318
6viral transcription (GO:0019083)4.63684268
7DNA strand elongation (GO:0022616)4.63315813
8ribosomal small subunit biogenesis (GO:0042274)4.59223020
9translational termination (GO:0006415)4.52206788
10telomere maintenance via recombination (GO:0000722)4.40827833
11positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)4.22745876
12ribosomal large subunit biogenesis (GO:0042273)4.15924857
13translational elongation (GO:0006414)4.11568040
14negative T cell selection (GO:0043383)4.08064145
15SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.06189522
16DNA replication checkpoint (GO:0000076)3.98991536
17formation of translation preinitiation complex (GO:0001731)3.98222267
18mitotic recombination (GO:0006312)3.97600946
19DNA replication initiation (GO:0006270)3.97016213
20cotranslational protein targeting to membrane (GO:0006613)3.96574042
21protein targeting to ER (GO:0045047)3.93225137
22telomere maintenance via telomere lengthening (GO:0010833)3.87302481
23translational initiation (GO:0006413)3.83107165
24nucleobase biosynthetic process (GO:0046112)3.79911007
25ribonucleoprotein complex biogenesis (GO:0022613)3.77060498
26nucleotide-excision repair, DNA gap filling (GO:0006297)3.75168566
27protein localization to endoplasmic reticulum (GO:0070972)3.74377218
28purine nucleobase biosynthetic process (GO:0009113)3.71332761
29establishment of protein localization to endoplasmic reticulum (GO:0072599)3.71072376
30purine deoxyribonucleotide catabolic process (GO:0009155)3.68354180
31nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.65935926
32proteasome assembly (GO:0043248)3.64438410
33deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.63810542
34pseudouridine synthesis (GO:0001522)3.60014905
35negative thymic T cell selection (GO:0045060)3.59896854
36cellular protein complex disassembly (GO:0043624)3.56997506
37protein complex biogenesis (GO:0070271)3.54120171
38rRNA processing (GO:0006364)3.53594385
39viral life cycle (GO:0019058)3.51795008
40rRNA modification (GO:0000154)3.51072839
41CENP-A containing nucleosome assembly (GO:0034080)3.50820470
42chromatin remodeling at centromere (GO:0031055)3.47905618
43rRNA metabolic process (GO:0016072)3.43557505
44cytochrome complex assembly (GO:0017004)3.43515667
45antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.42842460
46transcription-coupled nucleotide-excision repair (GO:0006283)3.41386029
47mitochondrial respiratory chain complex I assembly (GO:0032981)3.40419538
48NADH dehydrogenase complex assembly (GO:0010257)3.40419538
49mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.40419538
50positive regulation of gamma-delta T cell activation (GO:0046645)3.38102860
51peptidyl-histidine modification (GO:0018202)3.37175430
52translation (GO:0006412)3.35851339
53ribosome biogenesis (GO:0042254)3.33390962
54cellular response to interferon-beta (GO:0035458)3.32088905
55respiratory chain complex IV assembly (GO:0008535)3.29681244
56transcription elongation from RNA polymerase III promoter (GO:0006385)3.28479886
57termination of RNA polymerase III transcription (GO:0006386)3.28479886
58negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.23654966
59negative regulation of cell killing (GO:0031342)3.23654966
60protein complex disassembly (GO:0043241)3.22832525
61response to interferon-beta (GO:0035456)3.20909068
62mitotic metaphase plate congression (GO:0007080)3.20641377
63negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.19205377
64spliceosomal snRNP assembly (GO:0000387)3.18544538
65mitochondrial respiratory chain complex assembly (GO:0033108)3.17656874
66deoxyribonucleoside triphosphate metabolic process (GO:0009200)3.17457890
67DNA unwinding involved in DNA replication (GO:0006268)3.15981592
68NIK/NF-kappaB signaling (GO:0038061)3.15962149
69tolerance induction (GO:0002507)3.13413834
70cellular component biogenesis (GO:0044085)3.13387213
71regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.12839134
72IMP biosynthetic process (GO:0006188)3.12168733
73maturation of 5.8S rRNA (GO:0000460)3.11257016
74meiotic chromosome segregation (GO:0045132)3.11203537
75regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.10941073
76macromolecular complex disassembly (GO:0032984)3.08946819
77attachment of spindle microtubules to kinetochore (GO:0008608)3.08928709
78viral mRNA export from host cell nucleus (GO:0046784)3.08398784
79anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.07460665
80RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.07329761
81tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.07329761
82termination of RNA polymerase I transcription (GO:0006363)3.06889144
83exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.06785817
84transcription elongation from RNA polymerase I promoter (GO:0006362)3.05674116
85deoxyribonucleotide catabolic process (GO:0009264)3.05483543
86kinetochore organization (GO:0051383)3.04387136
87cellular response to interleukin-15 (GO:0071350)3.04313678
88positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.03612503
89DNA replication-independent nucleosome assembly (GO:0006336)3.03082259
90DNA replication-independent nucleosome organization (GO:0034724)3.03082259
91nuclear-transcribed mRNA catabolic process (GO:0000956)3.00987745
927-methylguanosine mRNA capping (GO:0006370)3.00486132
93protein localization to kinetochore (GO:0034501)3.00396835
94piRNA metabolic process (GO:0034587)2.99822382
95purine deoxyribonucleotide metabolic process (GO:0009151)2.99288435
96RNA capping (GO:0036260)2.98689991
977-methylguanosine RNA capping (GO:0009452)2.98689991
98iron-sulfur cluster assembly (GO:0016226)2.98128627
99metallo-sulfur cluster assembly (GO:0031163)2.98128627
100protein deneddylation (GO:0000338)2.97910686
101negative regulation of ligase activity (GO:0051352)2.95826124
102negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.95826124
103purine deoxyribonucleoside triphosphate metabolic process (GO:0009215)2.95529116
104nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.94366437
105mast cell activation involved in immune response (GO:0002279)2.94297905
106mast cell degranulation (GO:0043303)2.94297905
107histone exchange (GO:0043486)2.94039735
108protein localization to chromosome, centromeric region (GO:0071459)2.93170214
109deoxyribose phosphate catabolic process (GO:0046386)2.92342694
110rRNA methylation (GO:0031167)2.91686958
111telomere maintenance (GO:0000723)2.90976080
112L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.90165519
113cell wall macromolecule metabolic process (GO:0044036)2.89659319
114telomere organization (GO:0032200)2.89110505
115transcription from RNA polymerase I promoter (GO:0006360)2.89053141
116mitotic nuclear envelope disassembly (GO:0007077)2.88293437
117IMP metabolic process (GO:0046040)2.85888893
118mRNA catabolic process (GO:0006402)2.85857484
119negative regulation of mast cell activation (GO:0033004)2.84454301
120G1/S transition of mitotic cell cycle (GO:0000082)2.84164149
121cell cycle G1/S phase transition (GO:0044843)2.84164149
122cullin deneddylation (GO:0010388)2.82665821
123RNA catabolic process (GO:0006401)2.81937808
124metaphase plate congression (GO:0051310)2.81064775
125DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.80792981
126mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.79362086
127kinetochore assembly (GO:0051382)2.78426098
128negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)2.78318606
129positive regulation of alpha-beta T cell proliferation (GO:0046641)2.78237050
130maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.77897605
131intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.76999300
132signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.76999300
133regulation of nuclear cell cycle DNA replication (GO:0033262)2.76775762
134mast cell activation (GO:0045576)2.76043792
135signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.75627862
136signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.75627862
137signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.75627862
138ribosome assembly (GO:0042255)2.73005238
139pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.72307947
140chaperone-mediated protein transport (GO:0072321)2.72212861
141positive T cell selection (GO:0043368)2.71864013
142mismatch repair (GO:0006298)2.71206421
143positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.69577607
144ATP synthesis coupled proton transport (GO:0015986)2.68156435
145energy coupled proton transport, down electrochemical gradient (GO:0015985)2.68156435
146RNA destabilization (GO:0050779)2.68024260
147regulation of gamma-delta T cell activation (GO:0046643)2.67903192
148regulation of gamma-delta T cell differentiation (GO:0045586)2.67886669
1492-deoxyribonucleotide metabolic process (GO:0009394)2.67378118
150positive regulation of megakaryocyte differentiation (GO:0045654)2.65978309
151positive regulation of protein homooligomerization (GO:0032464)2.64707679
152ubiquinone biosynthetic process (GO:0006744)2.64243336
153positive regulation of chemokine secretion (GO:0090197)2.64119069
154base-excision repair, AP site formation (GO:0006285)2.62220429
155regulation of B cell receptor signaling pathway (GO:0050855)2.61921675
156Arp2/3 complex-mediated actin nucleation (GO:0034314)2.59751609
157response to interleukin-15 (GO:0070672)2.55478549
158establishment of protein localization to mitochondrial membrane (GO:0090151)2.54529630
159male meiosis I (GO:0007141)2.53471337
160regulation of mitochondrial translation (GO:0070129)2.53251397
161response to pheromone (GO:0019236)2.52813053
162T cell selection (GO:0045058)2.52558834
163deoxyribose phosphate metabolic process (GO:0019692)2.52091143
164mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.51982695
165regulation of alpha-beta T cell proliferation (GO:0046640)2.51953788
166negative regulation of B cell apoptotic process (GO:0002903)2.50428664
167positive regulation of hematopoietic progenitor cell differentiation (GO:1901534)2.48523464
168sperm motility (GO:0030317)2.47197861
169thymic T cell selection (GO:0045061)2.46277727
170mannosylation (GO:0097502)2.43829403
171respiratory electron transport chain (GO:0022904)2.43429902
172multicellular organism reproduction (GO:0032504)2.42679411
173electron transport chain (GO:0022900)2.42656442
174T cell migration (GO:0072678)2.40679855
175regulation of T cell receptor signaling pathway (GO:0050856)2.38248679
176dendritic cell chemotaxis (GO:0002407)2.37209208
177meiosis I (GO:0007127)2.35559235
178negative regulation of phagocytosis (GO:0050765)2.35123979
179protein targeting to mitochondrion (GO:0006626)2.34917936
180regulation of interleukin-1 beta secretion (GO:0050706)2.34855377
181regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.32624496
182positive thymic T cell selection (GO:0045059)2.32487953
183pyrimidine nucleotide catabolic process (GO:0006244)2.31824650
184negative regulation of DNA-templated transcription, elongation (GO:0032785)2.30427310
185regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.30201117
186positive regulation of interleukin-1 beta secretion (GO:0050718)2.29528296
187activated T cell proliferation (GO:0050798)2.29225046
188glucosamine-containing compound catabolic process (GO:1901072)2.28404498
189cytokine biosynthetic process (GO:0042089)2.28183608

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.79917542
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.13088436
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.69322463
4EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.64762624
5JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.35600695
6EST1_17652178_ChIP-ChIP_JURKAT_Human3.27095507
7GABP_17652178_ChIP-ChIP_JURKAT_Human3.25721375
8NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.12491585
9ETS1_20019798_ChIP-Seq_JURKAT_Human3.06774315
10E2F4_17652178_ChIP-ChIP_JURKAT_Human3.02527106
11MYC_18358816_ChIP-ChIP_MESCs_Mouse2.96683433
12MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.84712726
13CREB1_15753290_ChIP-ChIP_HEK293T_Human2.82179459
14FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.81432786
15BP1_19119308_ChIP-ChIP_Hs578T_Human2.73630572
16MYC_19030024_ChIP-ChIP_MESCs_Mouse2.68330634
17HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.66386583
18MYC_19079543_ChIP-ChIP_MESCs_Mouse2.64895094
19TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.57832949
20FOXM1_23109430_ChIP-Seq_U2OS_Human2.50168517
21ELF1_17652178_ChIP-ChIP_JURKAT_Human2.44323089
22VDR_23849224_ChIP-Seq_CD4+_Human2.42824876
23XRN2_22483619_ChIP-Seq_HELA_Human2.31820893
24FOXP3_21729870_ChIP-Seq_TREG_Human2.24193753
25SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.23947896
26HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.22399819
27CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.17499257
28HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.16999517
29DCP1A_22483619_ChIP-Seq_HELA_Human2.15664749
30SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.10434052
31NELFA_20434984_ChIP-Seq_ESCs_Mouse2.07815766
32E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.03575834
33E2F1_18555785_ChIP-Seq_MESCs_Mouse2.02455783
34GABP_19822575_ChIP-Seq_HepG2_Human1.98491251
35FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.93929256
36TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.91621188
37THAP11_20581084_ChIP-Seq_MESCs_Mouse1.90763535
38SRF_21415370_ChIP-Seq_HL-1_Mouse1.88510864
39MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.83890035
40TTF2_22483619_ChIP-Seq_HELA_Human1.83050956
41FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.81020026
42HOXB4_20404135_ChIP-ChIP_EML_Mouse1.75481748
43YY1_21170310_ChIP-Seq_MESCs_Mouse1.74989687
44PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.74530289
45IRF8_21731497_ChIP-ChIP_J774_Mouse1.73118343
46ELF1_20517297_ChIP-Seq_JURKAT_Human1.71952851
47E2F1_21310950_ChIP-Seq_MCF-7_Human1.67779695
48MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.66982300
49EBNA2_21746931_ChIP-Seq_IB4-LCL_Human1.65637985
50BCL6_27268052_Chip-Seq_Bcells_Human1.65151228
51CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.64266327
52NOTCH1_21737748_ChIP-Seq_TLL_Human1.63373789
53ERG_20887958_ChIP-Seq_HPC-7_Mouse1.62906813
54ZNF274_21170338_ChIP-Seq_K562_Hela1.62414710
55CIITA_25753668_ChIP-Seq_RAJI_Human1.61611209
56STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.59102634
57ELK1_19687146_ChIP-ChIP_HELA_Human1.57662084
58ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.56532842
59YY1_22570637_ChIP-Seq_MALME-3M_Human1.54835617
60MYB_26560356_Chip-Seq_TH2_Human1.54239085
61SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.53501845
62MYCN_18555785_ChIP-Seq_MESCs_Mouse1.52571894
63SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.51739045
64UTX_26944678_Chip-Seq_JUKART_Human1.49627084
65MAF_26560356_Chip-Seq_TH2_Human1.46549144
66POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.46174664
67YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.45054831
68RBPJ_21746931_ChIP-Seq_IB4-LCL_Human1.42811054
69NANOG_18555785_ChIP-Seq_MESCs_Mouse1.39484973
70IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.38793470
71PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.36565790
72ZFX_18555785_ChIP-Seq_MESCs_Mouse1.36313392
73LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.36080682
74AR_21909140_ChIP-Seq_LNCAP_Human1.35840476
75IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.30439259
76RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.29700990
77P68_20966046_ChIP-Seq_HELA_Human1.29297726
78PHF8_20622854_ChIP-Seq_HELA_Human1.29163453
79P300_27268052_Chip-Seq_Bcells_Human1.28747912
80BCOR_27268052_Chip-Seq_Bcells_Human1.27954895
81KDM5A_27292631_Chip-Seq_BREAST_Human1.27832034
82MYC_22102868_ChIP-Seq_BL_Human1.27096090
83ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.26788970
84CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.25746748
85SPI1_23547873_ChIP-Seq_NB4_Human1.24745531
86FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.24020002
87E2F1_20622854_ChIP-Seq_HELA_Human1.23554531
88E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.22698395
89ERA_21632823_ChIP-Seq_H3396_Human1.21772806
90GATA3_26560356_Chip-Seq_TH2_Human1.19734489
91MYB_26560356_Chip-Seq_TH1_Human1.16495958
92RAC3_21632823_ChIP-Seq_H3396_Human1.14480920
93CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.13135033
94NANOG_20526341_ChIP-Seq_ESCs_Human1.12908183
95MAF_26560356_Chip-Seq_TH1_Human1.12480801
96STAT1_20625510_ChIP-Seq_HELA_Human1.09901148
97GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.09759119
98GATA3_27048872_Chip-Seq_THYMUS_Human1.09636118
99IRF1_19129219_ChIP-ChIP_H3396_Human1.08525090
100BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.08276923
101CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.08032950
102FOXP1_21924763_ChIP-Seq_HESCs_Human1.07911815
103VDR_21846776_ChIP-Seq_THP-1_Human1.06102312
104E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.05529458
105CTCF_26484167_Chip-Seq_Bcells_Mouse1.04063399
106CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.03902081
107SPI1_20517297_ChIP-Seq_HL60_Human1.02927775
108CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.02091152
109CTCF_20526341_ChIP-Seq_ESCs_Human1.01949284
110ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.01409464
111EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.01224425
112SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.00740302
113RBPJ_22232070_ChIP-Seq_NCS_Mouse1.00197324
114KLF4_18555785_ChIP-Seq_MESCs_Mouse0.99605546
115MYC_18940864_ChIP-ChIP_HL60_Human0.99146449
116PADI4_21655091_ChIP-ChIP_MCF-7_Human0.98177948
117SCL_19346495_ChIP-Seq_HPC-7_Human0.98063831
118MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.95865540
119MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.95551338
120POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.93129956
121CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.91181958
122GATA1_22383799_ChIP-Seq_G1ME_Mouse0.90621009
123SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.87789896
124DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.87033154
125ELK1_22589737_ChIP-Seq_MCF10A_Human0.86922917
126CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.86729156
127FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.86502273
128STAT3_1855785_ChIP-Seq_MESCs_Mouse0.86331130
129CTCF_18555785_ChIP-Seq_MESCs_Mouse0.86075491
130TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.85060057
131TFEB_21752829_ChIP-Seq_HELA_Human0.84542345
132GATA2_22383799_ChIP-Seq_G1ME_Mouse0.84035668
133CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.79191923
134IRF8_22096565_ChIP-ChIP_GC-B_Human0.78222473
135STAT4_19710469_ChIP-ChIP_TH1__Mouse0.77633802
136PU.1_20513432_ChIP-Seq_Bcells_Mouse0.77375360
137KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.76653095
138TP63_19390658_ChIP-ChIP_HaCaT_Human0.76110958
139HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.75594436

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.43840815
2MP0010094_abnormal_chromosome_stability4.33714595
3MP0004957_abnormal_blastocyst_morpholog3.94302267
4MP0003111_abnormal_nucleus_morphology3.62832634
5MP0003077_abnormal_cell_cycle3.56399194
6MP0008057_abnormal_DNA_replication3.54820064
7MP0008058_abnormal_DNA_repair3.51338285
8MP0002396_abnormal_hematopoietic_system3.00068327
9MP0008877_abnormal_DNA_methylation2.74884266
10MP0008007_abnormal_cellular_replicative2.50716646
11MP0005451_abnormal_body_composition2.42785644
12MP0008932_abnormal_embryonic_tissue2.22085260
13MP0002163_abnormal_gland_morphology2.19305622
14MP0000490_abnormal_crypts_of2.18023276
15MP0005410_abnormal_fertilization2.07919135
16MP0003763_abnormal_thymus_physiology2.06416926
17MP0003786_premature_aging2.02010147
18MP0004808_abnormal_hematopoietic_stem1.97385508
19MP0006036_abnormal_mitochondrial_physio1.95603257
20MP0001790_abnormal_immune_system1.87028917
21MP0005387_immune_system_phenotype1.87028917
22MP0009379_abnormal_foot_pigmentation1.84943368
23MP0009333_abnormal_splenocyte_physiolog1.84653704
24MP0003718_maternal_effect1.82573176
25MP0005377_hearing/vestibular/ear_phenot1.79973037
26MP0003878_abnormal_ear_physiology1.79973037
27MP0001545_abnormal_hematopoietic_system1.78095787
28MP0005397_hematopoietic_system_phenotyp1.78095787
29MP0001929_abnormal_gametogenesis1.76499032
30MP0009697_abnormal_copulation1.76354888
31MP0006292_abnormal_olfactory_placode1.72267251
32MP0003787_abnormal_imprinting1.71315224
33MP0005379_endocrine/exocrine_gland_phen1.68132785
34MP0002398_abnormal_bone_marrow1.61215361
35MP0001348_abnormal_lacrimal_gland1.60827029
36MP0002132_abnormal_respiratory_system1.59953503
37MP0002210_abnormal_sex_determination1.57507776
38MP0000689_abnormal_spleen_morphology1.53753396
39MP0002138_abnormal_hepatobiliary_system1.53493477
40MP0000372_irregular_coat_pigmentation1.50455413
41MP0000350_abnormal_cell_proliferation1.50278543
42MP0001764_abnormal_homeostasis1.50192307
43MP0004147_increased_porphyrin_level1.49481791
44MP0005671_abnormal_response_to1.49413092
45MP0005075_abnormal_melanosome_morpholog1.48760607
46MP0002019_abnormal_tumor_incidence1.48672797
47MP0001730_embryonic_growth_arrest1.47796330
48MP0009785_altered_susceptibility_to1.47732235
49MP0001986_abnormal_taste_sensitivity1.47483817
50MP0003806_abnormal_nucleotide_metabolis1.47429353
51MP0006082_CNS_inflammation1.46523538
52MP0001835_abnormal_antigen_presentation1.44904951
53MP0002722_abnormal_immune_system1.44001253
54MP0002102_abnormal_ear_morphology1.43164740
55MP0000313_abnormal_cell_death1.41675595
56MP0003123_paternal_imprinting1.41453751
57MP0003011_delayed_dark_adaptation1.39480183
58MP0003186_abnormal_redox_activity1.33085345
59MP0002429_abnormal_blood_cell1.31530707
60MP0000703_abnormal_thymus_morphology1.29295593
61MP0001145_abnormal_male_reproductive1.28712336
62MP0002277_abnormal_respiratory_mucosa1.25803856
63MP0001800_abnormal_humoral_immune1.25037669
64MP0000716_abnormal_immune_system1.24363678
65MP0003303_peritoneal_inflammation1.24063778
66MP0000465_gastrointestinal_hemorrhage1.20580586
67MP0000653_abnormal_sex_gland1.20254797
68MP0003698_abnormal_male_reproductive1.17431285
69MP0002420_abnormal_adaptive_immunity1.17027150
70MP0001819_abnormal_immune_cell1.15252188
71MP0005025_abnormal_response_to1.10833971
72MP0003656_abnormal_erythrocyte_physiolo1.10523626
73MP0000358_abnormal_cell_content/1.09893897
74MP0002080_prenatal_lethality1.09603869
75MP0009764_decreased_sensitivity_to1.09445107
76MP0002166_altered_tumor_susceptibility1.09074225
77MP0001873_stomach_inflammation1.09040466
78MP0008872_abnormal_physiological_respon1.08787192
79MP0002723_abnormal_immune_serum1.07913031
80MP0001697_abnormal_embryo_size1.07891676
81MP0002095_abnormal_skin_pigmentation1.06650424
82MP0002452_abnormal_antigen_presenting1.06467761
83MP0010155_abnormal_intestine_physiology1.05982248
84MP0003866_abnormal_defecation1.05755424
85MP0005174_abnormal_tail_pigmentation1.04936810
86MP0008469_abnormal_protein_level1.04551902
87MP0002837_dystrophic_cardiac_calcinosis1.03420210
88MP0001853_heart_inflammation1.03337538
89MP0005084_abnormal_gallbladder_morpholo1.01049179
90MP0001119_abnormal_female_reproductive1.00613262
91MP0005380_embryogenesis_phenotype0.99756801
92MP0001672_abnormal_embryogenesis/_devel0.99756801
93MP0002876_abnormal_thyroid_physiology0.98833273
94MP0005645_abnormal_hypothalamus_physiol0.98808248
95MP0003315_abnormal_perineum_morphology0.98392792
96MP0003567_abnormal_fetal_cardiomyocyte0.97480925
97MP0005646_abnormal_pituitary_gland0.97059429
98MP0006035_abnormal_mitochondrial_morpho0.95883245
99MP0008875_abnormal_xenobiotic_pharmacok0.95476569
100MP0002006_tumorigenesis0.95127339
101MP0001533_abnormal_skeleton_physiology0.94119528
102MP0006054_spinal_hemorrhage0.92739761
103MP0005310_abnormal_salivary_gland0.90615041
104MP0002160_abnormal_reproductive_system0.89387402
105MP0002693_abnormal_pancreas_physiology0.89262715
106MP0009278_abnormal_bone_marrow0.88869644
107MP0005464_abnormal_platelet_physiology0.87838437
108MP0003724_increased_susceptibility_to0.86533686
109MP0002405_respiratory_system_inflammati0.86100212
110MP0000685_abnormal_immune_system0.85104260
111MP0004381_abnormal_hair_follicle0.84522292
112MP0003984_embryonic_growth_retardation0.84518515
113MP0005389_reproductive_system_phenotype0.84341572
114MP0003943_abnormal_hepatobiliary_system0.83507836
115MP0002161_abnormal_fertility/fecundity0.82704446
116MP0003436_decreased_susceptibility_to0.82679806
117MP0005083_abnormal_biliary_tract0.81689594
118MP0002088_abnormal_embryonic_growth/wei0.81599500
119MP0005000_abnormal_immune_tolerance0.80022008
120MP0005266_abnormal_metabolism0.79611226
121MP0002009_preneoplasia0.79545757
122MP0002148_abnormal_hypersensitivity_rea0.78819021
123MP0004142_abnormal_muscle_tone0.78014745
124MP0005551_abnormal_eye_electrophysiolog0.77773795
125MP0003646_muscle_fatigue0.77710141
126MP0009765_abnormal_xenobiotic_induced0.76636916
127MP0001919_abnormal_reproductive_system0.76363696
128MP0001968_abnormal_touch/_nociception0.76219097
129MP0000858_altered_metastatic_potential0.73819859
130MP0004043_abnormal_pH_regulation0.73185240
131MP0005670_abnormal_white_adipose0.71129163
132MP0001845_abnormal_inflammatory_respons0.70969527
133MP0002419_abnormal_innate_immunity0.70581040
134MP0002653_abnormal_ependyma_morphology0.66959619
135MP0003221_abnormal_cardiomyocyte_apopto0.66335513
136MP0010307_abnormal_tumor_latency0.66247542
137MP0008260_abnormal_autophagy0.65653138
138MP0004264_abnormal_extraembryonic_tissu0.65462700
139MP0002086_abnormal_extraembryonic_tissu0.65108867
140MP0008995_early_reproductive_senescence0.65074029
141MP0002254_reproductive_system_inflammat0.63908115

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)5.37505309
2Abnormal number of erythroid precursors (HP:0012131)5.32680475
3Reticulocytopenia (HP:0001896)4.75564412
4Aplastic anemia (HP:0001915)4.73027590
5Birth length less than 3rd percentile (HP:0003561)3.90390756
6Oral leukoplakia (HP:0002745)3.84896865
7Thrombocytosis (HP:0001894)3.81311171
8IgM deficiency (HP:0002850)3.56821416
9Increased IgM level (HP:0003496)3.43539664
10Pallor (HP:0000980)3.28269537
11Macrocytic anemia (HP:0001972)3.27857863
12Stomatitis (HP:0010280)3.27169489
13Abnormality of the heme biosynthetic pathway (HP:0010472)3.25686575
14Hepatocellular necrosis (HP:0001404)3.24928736
15Type 2 muscle fiber atrophy (HP:0003554)3.24164109
16Elevated erythrocyte sedimentation rate (HP:0003565)3.22640927
17Severe visual impairment (HP:0001141)3.22086920
18Muscle fiber atrophy (HP:0100295)3.16664388
19Type I transferrin isoform profile (HP:0003642)3.14223745
20Chromsome breakage (HP:0040012)3.07163951
21Abnormal rod and cone electroretinograms (HP:0008323)3.03788123
22Pancytopenia (HP:0001876)3.01108538
23Decreased activity of mitochondrial respiratory chain (HP:0008972)2.98948306
24Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.98948306
25Hepatic necrosis (HP:0002605)2.97200234
26Abnormality of the preputium (HP:0100587)2.94259776
27Rough bone trabeculation (HP:0100670)2.88340273
28Chromosomal breakage induced by crosslinking agents (HP:0003221)2.77538276
2911 pairs of ribs (HP:0000878)2.76231947
30Abnormal spermatogenesis (HP:0008669)2.76002339
31Mitochondrial inheritance (HP:0001427)2.74719128
32Abnormality of chromosome stability (HP:0003220)2.74658061
33Myelodysplasia (HP:0002863)2.69692017
34Severe combined immunodeficiency (HP:0004430)2.68339253
35Petechiae (HP:0000967)2.67043552
36Increased serum lactate (HP:0002151)2.66589716
37Breast hypoplasia (HP:0003187)2.64875403
38Increased CSF lactate (HP:0002490)2.64540563
39Renal Fanconi syndrome (HP:0001994)2.64327606
40Increased muscle lipid content (HP:0009058)2.62653648
41Acute necrotizing encephalopathy (HP:0006965)2.60665839
42Degeneration of anterior horn cells (HP:0002398)2.58712414
43Abnormality of the anterior horn cell (HP:0006802)2.58712414
443-Methylglutaconic aciduria (HP:0003535)2.58608184
45Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.55454906
46Eosinophilia (HP:0001880)2.52800227
47Abnormal delayed hypersensitivity skin test (HP:0002963)2.52058123
48Meckel diverticulum (HP:0002245)2.51332621
49Abnormality of eosinophils (HP:0001879)2.51172225
50Autoimmune thrombocytopenia (HP:0001973)2.50630975
51Absent rod-and cone-mediated responses on ERG (HP:0007688)2.49393320
52Abnormality of B cell number (HP:0010975)2.49291252
53Granulocytopenia (HP:0001913)2.49290706
54Colon cancer (HP:0003003)2.48813072
55Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.48324472
56Cerebral hypomyelination (HP:0006808)2.47675449
57Reduced antithrombin III activity (HP:0001976)2.45953164
58Abnormal mitochondria in muscle tissue (HP:0008316)2.45609023
59Bone marrow hypocellularity (HP:0005528)2.44451045
60Abnormality of the ileum (HP:0001549)2.43592601
61Aplasia/Hypoplasia of the sacrum (HP:0008517)2.39781993
62Attenuation of retinal blood vessels (HP:0007843)2.39678154
63Absent thumb (HP:0009777)2.38381756
64Carpal bone hypoplasia (HP:0001498)2.37604110
65Recurrent fungal infections (HP:0002841)2.37382452
66Recurrent bronchitis (HP:0002837)2.35732694
67Cerebral palsy (HP:0100021)2.35667618
68Eczematoid dermatitis (HP:0000976)2.34974113
69Myositis (HP:0100614)2.33271503
70Abnormality of T cell number (HP:0011839)2.32153470
71Impulsivity (HP:0100710)2.31745947
72Patellar aplasia (HP:0006443)2.31465421
73Autoimmune hemolytic anemia (HP:0001890)2.29787482
74Abnormal glycosylation (HP:0012345)2.29088373
75Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.29088373
76Abnormal protein N-linked glycosylation (HP:0012347)2.29088373
77Abnormal protein glycosylation (HP:0012346)2.29088373
78Optic disc pallor (HP:0000543)2.28716006
79Cerebral edema (HP:0002181)2.28457283
80Microvesicular hepatic steatosis (HP:0001414)2.28094432
81Respiratory failure (HP:0002878)2.25857286
82Prostate neoplasm (HP:0100787)2.22880048
83Dicarboxylic aciduria (HP:0003215)2.21476857
84Abnormality of dicarboxylic acid metabolism (HP:0010995)2.21476857
85Premature ovarian failure (HP:0008209)2.21474644
86Cellular immunodeficiency (HP:0005374)2.20739846
87Aplasia/Hypoplasia of the uvula (HP:0010293)2.20253474
88Hypochromic anemia (HP:0001931)2.19776623
89Optic neuritis (HP:0100653)2.17286715
90Retrobulbar optic neuritis (HP:0100654)2.17286715
91Respiratory difficulties (HP:0002880)2.17069965
92Increased hepatocellular lipid droplets (HP:0006565)2.16844117
93Microretrognathia (HP:0000308)2.15558830
94Aplasia/Hypoplasia of the patella (HP:0006498)2.15546937
95Congenital stationary night blindness (HP:0007642)2.14728470
96Lactic acidosis (HP:0003128)2.14331007
97Premature graying of hair (HP:0002216)2.13743254
98Lymphoma (HP:0002665)2.13183314
99Renal cortical cysts (HP:0000803)2.12611954
100Stomach cancer (HP:0012126)2.12301741
101Chronic obstructive pulmonary disease (HP:0006510)2.11950689
102Obstructive lung disease (HP:0006536)2.11950689
103Selective tooth agenesis (HP:0001592)2.11609052
104Combined immunodeficiency (HP:0005387)2.10931523
105Exertional dyspnea (HP:0002875)2.09684015
106Cleft eyelid (HP:0000625)2.09306833
107Progressive microcephaly (HP:0000253)2.08565870
108Emotional lability (HP:0000712)2.07455703
109Abnormality of the renal cortex (HP:0011035)2.07171889
110Generalized aminoaciduria (HP:0002909)2.07015770
111Panhypogammaglobulinemia (HP:0003139)2.05949330
112IgG deficiency (HP:0004315)2.05377002
113Neutropenia (HP:0001875)2.05204514
114Duodenal stenosis (HP:0100867)2.04409318
115Small intestinal stenosis (HP:0012848)2.04409318
116B lymphocytopenia (HP:0010976)2.04213416
117Abnormal lung lobation (HP:0002101)2.03303585
118Encephalitis (HP:0002383)2.03267750
119Sloping forehead (HP:0000340)2.02648987
120Acute encephalopathy (HP:0006846)2.01923787
121Vasculitis (HP:0002633)2.01513283
122Ragged-red muscle fibers (HP:0003200)2.00003397
123Pulmonary fibrosis (HP:0002206)1.99906259
124Leukocytosis (HP:0001974)1.99286376
125Exercise intolerance (HP:0003546)1.99025125
126Nephronophthisis (HP:0000090)1.98854205
127Hypoplasia of the capital femoral epiphysis (HP:0003090)1.98536025
128Multiple enchondromatosis (HP:0005701)1.98265298
129Bronchitis (HP:0012387)1.97965023
130Orchitis (HP:0100796)1.97615763
131Sparse eyelashes (HP:0000653)1.97553936
132Decreased electroretinogram (ERG) amplitude (HP:0000654)1.96566179
133Secondary amenorrhea (HP:0000869)1.96420406
134Lipid accumulation in hepatocytes (HP:0006561)1.95876007
135Abnormality of the prostate (HP:0008775)1.95566794
136Medulloblastoma (HP:0002885)1.95044258
137Abnormal trabecular bone morphology (HP:0100671)1.94166688
138T lymphocytopenia (HP:0005403)1.93805655
139Tetany (HP:0001281)1.93663942
140Irregular epiphyses (HP:0010582)1.93590049
141Clubbing of toes (HP:0100760)1.93280022
142Recurrent cutaneous fungal infections (HP:0011370)1.91621720
143Chronic mucocutaneous candidiasis (HP:0002728)1.91621720
144Joint swelling (HP:0001386)1.90830153
145Agnosia (HP:0010524)1.89847647
146Pancreatic cysts (HP:0001737)1.89338670
147Lethargy (HP:0001254)1.88102840
148Abnormality of T cells (HP:0002843)1.87917818
149Triphalangeal thumb (HP:0001199)1.86795347
150Progressive macrocephaly (HP:0004481)1.86125234
151Supernumerary spleens (HP:0009799)1.84405917
152Aplasia/Hypoplasia of the spleen (HP:0010451)1.84368188
153Abnormality of T cell physiology (HP:0011840)1.83221499
154Progressive muscle weakness (HP:0003323)1.83038521
155Asplenia (HP:0001746)1.82705529
156Hypoplasia of the radius (HP:0002984)1.82277581
157Prolonged bleeding time (HP:0003010)1.80416107
158Lymphopenia (HP:0001888)1.79349823
159Methylmalonic aciduria (HP:0012120)1.78806209
160Abnormality of DNA repair (HP:0003254)1.78579990
161Acute hepatic failure (HP:0006554)1.77940703
162Hypochromic microcytic anemia (HP:0004840)1.77326007
163Increased intramyocellular lipid droplets (HP:0012240)1.76776937
164Abnormality of reticulocytes (HP:0004312)1.76143583
165Abnormal respiratory epithelium morphology (HP:0012253)1.75980333
166Abnormal respiratory motile cilium morphology (HP:0005938)1.75980333
167Mediastinal lymphadenopathy (HP:0100721)1.75787884
168Tubulointerstitial nephritis (HP:0001970)1.75206930
169Abnormality of cells of the lymphoid lineage (HP:0012140)1.74734222

Predicted kinase interactions (KEA)

RankGene SetZ-score
1VRK23.98378916
2BUB13.86153349
3WEE13.76245685
4STK163.67620655
5TAOK33.24485455
6EIF2AK13.16939837
7NME23.01326119
8ACVR1B2.71313817
9CDC72.60005979
10CCNB12.47598432
11PLK42.34965435
12GRK62.32259451
13SRPK12.25155436
14VRK12.24630747
15EIF2AK32.13373265
16BRSK22.07193882
17MAP4K22.02147455
18TSSK62.01252024
19NEK21.96579013
20TLK11.93076181
21MAP4K11.85361924
22TTK1.71980834
23TGFBR11.71473713
24DYRK31.67702719
25TESK21.64397223
26TEC1.58191647
27BCKDK1.56754027
28PLK11.54200236
29CDK71.44931292
30BRSK11.44221764
31RIPK41.42030544
32ATR1.41947839
33FES1.40426760
34AURKB1.39345318
35ADRBK21.38861007
36TNK21.36931539
37PIM21.33596059
38MAP2K21.33004883
39WNK41.31706612
40TESK11.30164897
41MAP2K31.24678263
42PASK1.24638239
43MKNK11.24357190
44CHEK21.23977676
45MAPKAPK31.23035530
46GRK11.22806851
47MUSK1.18411269
48STK241.17181397
49CDK81.15263340
50TRIM281.14468554
51ITK1.14231713
52IRAK41.12618302
53CDK191.11082980
54PDK31.11000398
55PDK41.11000398
56KDR1.08343903
57MKNK21.07601663
58BTK1.06866936
59TXK0.98470433
60TAOK10.97331113
61AURKA0.96692021
62KIT0.94243194
63CSNK1G30.93427547
64IRAK30.93092277
65EIF2AK20.92324700
66LIMK10.90715717
67ZAP700.90053905
68RPS6KB20.89884395
69CDK40.89042515
70LCK0.88716318
71TAOK20.87394076
72STK100.87255013
73BCR0.86331434
74PINK10.85089506
75PLK30.82403109
76PIM10.81881464
77RPS6KA40.81447085
78MAP3K60.81370665
79NEK10.80600993
80CSNK2A10.78618097
81MARK30.77943369
82PRKCQ0.77143605
83GRK70.75192759
84MAP2K60.70994091
85MATK0.69808421
86CHEK10.69606352
87MAP3K80.68922512
88MAP3K110.68193319
89TIE10.67313561
90STK40.67082204
91RPS6KA50.66153743
92WNK30.65703689
93CLK10.65617062
94TBK10.65244772
95BMPR1B0.65107830
96CSNK1G20.64472634
97CSNK1G10.63707654
98ERN10.63256135
99CSNK2A20.62676711
100ZAK0.62577068
101ILK0.61866345
102FLT30.60119738
103INSRR0.59808921
104MYLK0.59789526
105SYK0.57537762
106FRK0.57311571
107HCK0.56730813
108CSK0.55324478
109NME10.55098625
110BRAF0.54655566
111PAK10.52575500
112NLK0.52471372
113MAPK110.52417968
114CSNK1A1L0.51121346
115PRKCI0.50742541
116ATM0.50343993
117NUAK10.49224442
118MAPK130.48653066
119MAP3K120.48455075
120PHKG10.47899790
121PHKG20.47899790
122LYN0.47723313
123PAK40.47617879
124IKBKE0.46951549
125CSF1R0.46204331
126SIK30.45812598
127CDK20.44888285
128STK38L0.43820453
129BLK0.42281329
130JAK30.41561048
131LRRK20.41490953
132MST40.38388355
133PDK20.38368790
134RPS6KA10.37620310
135CAMKK20.37297309
136DYRK20.37109482
137MAPKAPK20.35804684
138ARAF0.35715169
139IKBKB0.35129523
140TYK20.34551562
141MAPK40.33370947
142ABL20.33071907
143DAPK10.31206140
144ADRBK10.27560042
145FGR0.26523534
146PRKCD0.25795523
147OBSCN0.25525958

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030305.13324454
2Ribosome_Homo sapiens_hsa030104.36684815
3Mismatch repair_Homo sapiens_hsa034304.35623007
4RNA polymerase_Homo sapiens_hsa030203.36505340
5Proteasome_Homo sapiens_hsa030503.36120741
6Homologous recombination_Homo sapiens_hsa034403.23388468
7Base excision repair_Homo sapiens_hsa034103.21065631
8Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.05767625
9Nucleotide excision repair_Homo sapiens_hsa034202.91295564
10Pyrimidine metabolism_Homo sapiens_hsa002402.81230140
11Spliceosome_Homo sapiens_hsa030402.63361659
12RNA transport_Homo sapiens_hsa030132.39857462
13Basal transcription factors_Homo sapiens_hsa030222.09850459
14Cell cycle_Homo sapiens_hsa041102.09723713
15One carbon pool by folate_Homo sapiens_hsa006702.03893473
16Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.99545523
17Autoimmune thyroid disease_Homo sapiens_hsa053201.98047556
18Fanconi anemia pathway_Homo sapiens_hsa034601.97810541
19Graft-versus-host disease_Homo sapiens_hsa053321.83057912
20RNA degradation_Homo sapiens_hsa030181.76522703
21Type I diabetes mellitus_Homo sapiens_hsa049401.75392697
22Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.68540310
23Non-homologous end-joining_Homo sapiens_hsa034501.67637532
24Phototransduction_Homo sapiens_hsa047441.66935779
25Purine metabolism_Homo sapiens_hsa002301.59267882
26Protein export_Homo sapiens_hsa030601.59013071
27Asthma_Homo sapiens_hsa053101.57247960
28Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.49624493
29Folate biosynthesis_Homo sapiens_hsa007901.35060050
30Vitamin B6 metabolism_Homo sapiens_hsa007501.27727357
31Parkinsons disease_Homo sapiens_hsa050121.21297226
32Caffeine metabolism_Homo sapiens_hsa002321.18304677
33T cell receptor signaling pathway_Homo sapiens_hsa046601.16389394
34Huntingtons disease_Homo sapiens_hsa050161.12770940
35Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.11628609
36Oxidative phosphorylation_Homo sapiens_hsa001901.11242870
37Drug metabolism - other enzymes_Homo sapiens_hsa009831.10211258
38Pentose phosphate pathway_Homo sapiens_hsa000301.07058746
39p53 signaling pathway_Homo sapiens_hsa041151.03522621
40Cysteine and methionine metabolism_Homo sapiens_hsa002701.00635393
41Epstein-Barr virus infection_Homo sapiens_hsa051691.00245260
42mRNA surveillance pathway_Homo sapiens_hsa030150.99516920
43Sulfur relay system_Homo sapiens_hsa041220.98918483
44Primary immunodeficiency_Homo sapiens_hsa053400.98029608
45Rheumatoid arthritis_Homo sapiens_hsa053230.95670952
46Butanoate metabolism_Homo sapiens_hsa006500.95055939
47Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.94690697
48Antigen processing and presentation_Homo sapiens_hsa046120.92716137
49Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.91025424
50Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.90502923
51Herpes simplex infection_Homo sapiens_hsa051680.90353472
52Selenocompound metabolism_Homo sapiens_hsa004500.84029387
53Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.77802197
54Collecting duct acid secretion_Homo sapiens_hsa049660.76086593
55Biosynthesis of amino acids_Homo sapiens_hsa012300.75855562
56Cyanoamino acid metabolism_Homo sapiens_hsa004600.71492656
57Cardiac muscle contraction_Homo sapiens_hsa042600.71150464
58Intestinal immune network for IgA production_Homo sapiens_hsa046720.70550650
59N-Glycan biosynthesis_Homo sapiens_hsa005100.69515152
60Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.68942097
61Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.68919085
62Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.66281229
63Viral myocarditis_Homo sapiens_hsa054160.64730513
64Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.64705114
65Glutathione metabolism_Homo sapiens_hsa004800.62817617
66Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.61971564
67Carbon metabolism_Homo sapiens_hsa012000.61725966
68Systemic lupus erythematosus_Homo sapiens_hsa053220.61258580
69Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.59690559
70African trypanosomiasis_Homo sapiens_hsa051430.58073408
71Staphylococcus aureus infection_Homo sapiens_hsa051500.55926940
72Measles_Homo sapiens_hsa051620.55121736
73Alzheimers disease_Homo sapiens_hsa050100.54933748
74Tryptophan metabolism_Homo sapiens_hsa003800.54423736
75Metabolic pathways_Homo sapiens_hsa011000.54395239
76Fructose and mannose metabolism_Homo sapiens_hsa000510.52992483
77Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.51596308
78RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.51401283
79Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.50748497
80Legionellosis_Homo sapiens_hsa051340.47960334
81Maturity onset diabetes of the young_Homo sapiens_hsa049500.46830142
82Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.46706574
83Osteoclast differentiation_Homo sapiens_hsa043800.46647958
84Fatty acid elongation_Homo sapiens_hsa000620.46075000
85Oocyte meiosis_Homo sapiens_hsa041140.45147519
86Toll-like receptor signaling pathway_Homo sapiens_hsa046200.43242026
87Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.42607790
88Arachidonic acid metabolism_Homo sapiens_hsa005900.42311174
89Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.41425767
90Galactose metabolism_Homo sapiens_hsa000520.39620301
91Chemical carcinogenesis_Homo sapiens_hsa052040.39566753
92Tuberculosis_Homo sapiens_hsa051520.38803584
93Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.35755233
94Hematopoietic cell lineage_Homo sapiens_hsa046400.35654458
95Viral carcinogenesis_Homo sapiens_hsa052030.34995492
96Pyruvate metabolism_Homo sapiens_hsa006200.34918195
97Malaria_Homo sapiens_hsa051440.34808536
98B cell receptor signaling pathway_Homo sapiens_hsa046620.34086249
99Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.33922063
100NF-kappa B signaling pathway_Homo sapiens_hsa040640.32367446
101Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.31471148
102HTLV-I infection_Homo sapiens_hsa051660.30761154
103NOD-like receptor signaling pathway_Homo sapiens_hsa046210.29194572
104Glycerophospholipid metabolism_Homo sapiens_hsa005640.28107159
105Thyroid cancer_Homo sapiens_hsa052160.27004507
106Shigellosis_Homo sapiens_hsa051310.26421151
107Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.26313532
108Regulation of autophagy_Homo sapiens_hsa041400.25666259
109SNARE interactions in vesicular transport_Homo sapiens_hsa041300.24964238
110Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.24733240
111Olfactory transduction_Homo sapiens_hsa047400.23312040
1122-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.21345385
113Transcriptional misregulation in cancer_Homo sapiens_hsa052020.20769294
114Linoleic acid metabolism_Homo sapiens_hsa005910.20027225
115Influenza A_Homo sapiens_hsa051640.19895930
116Apoptosis_Homo sapiens_hsa042100.19460087
117Leishmaniasis_Homo sapiens_hsa051400.19333265
118Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.18682085
119Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.17060024
120Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.16427358
121Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.15739790
122Jak-STAT signaling pathway_Homo sapiens_hsa046300.15652509
123Propanoate metabolism_Homo sapiens_hsa006400.15205413
124Other glycan degradation_Homo sapiens_hsa005110.09812587
125beta-Alanine metabolism_Homo sapiens_hsa004100.09459529
126Hepatitis B_Homo sapiens_hsa051610.08748658
127alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.08614091
128Acute myeloid leukemia_Homo sapiens_hsa052210.08454124
129Allograft rejection_Homo sapiens_hsa053300.08165892
130Peroxisome_Homo sapiens_hsa041460.07457230

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »