SGSM1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)6.28954110
2synaptic vesicle maturation (GO:0016188)6.00188625
3positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.92402053
4locomotory exploration behavior (GO:0035641)5.45496779
5synaptic vesicle exocytosis (GO:0016079)5.27915166
6regulation of synaptic vesicle exocytosis (GO:2000300)5.03368543
7glutamate secretion (GO:0014047)4.93262532
8neuromuscular process controlling posture (GO:0050884)4.87872975
9positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.85719777
10synaptic vesicle docking involved in exocytosis (GO:0016081)4.72759742
11vocalization behavior (GO:0071625)4.65414314
12neurotransmitter secretion (GO:0007269)4.49398823
13regulation of synaptic vesicle transport (GO:1902803)4.47003395
14regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.39961088
15behavioral response to nicotine (GO:0035095)4.28208730
16regulation of neuronal synaptic plasticity (GO:0048168)4.20458253
17synaptic vesicle endocytosis (GO:0048488)4.18409450
18regulation of glutamate receptor signaling pathway (GO:1900449)4.17732073
19gamma-aminobutyric acid transport (GO:0015812)4.15521867
20neuronal action potential propagation (GO:0019227)4.14603869
21regulation of respiratory gaseous exchange by neurological system process (GO:0002087)4.02440844
22regulation of long-term neuronal synaptic plasticity (GO:0048169)3.99289009
23ionotropic glutamate receptor signaling pathway (GO:0035235)3.98830088
24neuron cell-cell adhesion (GO:0007158)3.96884561
25exploration behavior (GO:0035640)3.94532495
26negative regulation of synaptic transmission, GABAergic (GO:0032229)3.89921122
27proline transport (GO:0015824)3.88927496
28protein localization to synapse (GO:0035418)3.88827966
29positive regulation of synaptic transmission, GABAergic (GO:0032230)3.82027273
30glycine transport (GO:0015816)3.81720332
31neuromuscular process controlling balance (GO:0050885)3.78398089
32synaptic transmission, glutamatergic (GO:0035249)3.74237244
33activation of protein kinase A activity (GO:0034199)3.71894036
34neurotransmitter transport (GO:0006836)3.71620166
35layer formation in cerebral cortex (GO:0021819)3.70228363
36central nervous system myelination (GO:0022010)3.59373772
37axon ensheathment in central nervous system (GO:0032291)3.59373772
38dendritic spine morphogenesis (GO:0060997)3.56129522
39startle response (GO:0001964)3.55972415
40cerebellar Purkinje cell differentiation (GO:0021702)3.52628326
41regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.52215408
42regulation of cAMP-dependent protein kinase activity (GO:2000479)3.50086738
43membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.48185291
44cellular potassium ion homeostasis (GO:0030007)3.42598998
45regulation of respiratory system process (GO:0044065)3.41941893
46long-term memory (GO:0007616)3.41764831
47neuron-neuron synaptic transmission (GO:0007270)3.40408440
48glutamate receptor signaling pathway (GO:0007215)3.40357548
49regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.40045065
50regulation of neurotransmitter levels (GO:0001505)3.36949679
51regulation of synapse structural plasticity (GO:0051823)3.36666766
52regulation of excitatory postsynaptic membrane potential (GO:0060079)3.36059567
53positive regulation of membrane potential (GO:0045838)3.34027234
54regulation of neurotransmitter secretion (GO:0046928)3.33857523
55cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.31290458
56pyrimidine nucleobase catabolic process (GO:0006208)3.29099125
57cell migration in hindbrain (GO:0021535)3.29093936
58sodium ion export (GO:0071436)3.26477547
59neuromuscular process (GO:0050905)3.24942217
60nucleobase catabolic process (GO:0046113)3.24796182
61response to pheromone (GO:0019236)3.24662546
62regulation of vesicle fusion (GO:0031338)3.24218419
63regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.24170149
64regulation of postsynaptic membrane potential (GO:0060078)3.22134431
65presynaptic membrane assembly (GO:0097105)3.22106240
66regulation of calcium ion-dependent exocytosis (GO:0017158)3.21255644
67negative regulation of cytosolic calcium ion concentration (GO:0051481)3.20669962
68regulation of synaptic plasticity (GO:0048167)3.18308544
69neurotransmitter-gated ion channel clustering (GO:0072578)3.16618564
70presynaptic membrane organization (GO:0097090)3.14980625
71positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.14157546
72cellular ketone body metabolic process (GO:0046950)3.13935936
73transmission of nerve impulse (GO:0019226)3.13487943
74regulation of neurotransmitter transport (GO:0051588)3.11577595
75positive regulation of dendritic spine morphogenesis (GO:0061003)3.10845378
76neuronal ion channel clustering (GO:0045161)3.10791766
77regulation of respiratory gaseous exchange (GO:0043576)3.10289614
78cerebellar Purkinje cell layer development (GO:0021680)3.09969255
79protein localization to cilium (GO:0061512)3.06764341
80neuronal action potential (GO:0019228)3.04868200
81G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.03782436
82cell communication by electrical coupling (GO:0010644)3.03198693
83L-fucose catabolic process (GO:0042355)3.03049716
84fucose catabolic process (GO:0019317)3.03049716
85L-fucose metabolic process (GO:0042354)3.03049716
86chemosensory behavior (GO:0007635)3.01336947
87postsynaptic membrane organization (GO:0001941)3.00358076
88regulation of neurotransmitter uptake (GO:0051580)2.99330450
89auditory behavior (GO:0031223)2.98690122
90membrane depolarization during action potential (GO:0086010)2.96266223
91serotonin metabolic process (GO:0042428)2.96211717
92establishment of synaptic vesicle localization (GO:0097480)2.96097758
93synaptic vesicle transport (GO:0048489)2.96097758
94vesicle transport along microtubule (GO:0047496)2.92870645
95signal release (GO:0023061)2.92706183
96positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.92367120
97proline biosynthetic process (GO:0006561)2.89752934
98negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.88121241
99dendrite morphogenesis (GO:0048813)2.86742052
100detection of calcium ion (GO:0005513)2.86578013
101epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.85464384
102membrane hyperpolarization (GO:0060081)2.85037565
103neuron recognition (GO:0008038)2.84595551
104response to auditory stimulus (GO:0010996)2.84140483
105regulation of dendritic spine morphogenesis (GO:0061001)2.82266975
106primary amino compound metabolic process (GO:1901160)2.82266566
107gamma-aminobutyric acid signaling pathway (GO:0007214)2.81263687
108membrane depolarization (GO:0051899)2.81192046
109innervation (GO:0060384)2.80703992
110positive regulation of exocytosis (GO:0045921)2.79546363
111positive regulation of neurotransmitter transport (GO:0051590)2.78434758
112regulation of synaptic transmission, glutamatergic (GO:0051966)2.78342835
113regulation of synaptic transmission (GO:0050804)2.78085177
114organelle transport along microtubule (GO:0072384)2.78015697
115regulation of exocytosis (GO:0017157)2.77230779
116regulation of synaptic transmission, GABAergic (GO:0032228)2.77075378
117neuromuscular synaptic transmission (GO:0007274)2.76739200
118positive regulation of dendritic spine development (GO:0060999)2.75529363
119ketone body metabolic process (GO:1902224)2.75429013
120synaptic transmission (GO:0007268)2.75280172
121positive regulation of synapse maturation (GO:0090129)2.75167573
122long-term synaptic potentiation (GO:0060291)2.73722254
123dendritic spine organization (GO:0097061)2.72991564
124glycosphingolipid biosynthetic process (GO:0006688)2.72795065
125prepulse inhibition (GO:0060134)2.72248706
126cellular potassium ion transport (GO:0071804)2.71237771
127potassium ion transmembrane transport (GO:0071805)2.71237771
128insulin secretion (GO:0030073)2.70264133
129protein polyglutamylation (GO:0018095)2.67520061
130calcium ion-dependent exocytosis (GO:0017156)2.66774403
131synapse assembly (GO:0007416)2.65510364
132regulation of cilium movement (GO:0003352)2.64753816
133action potential (GO:0001508)2.64605736
134regulation of action potential (GO:0098900)2.63967127
135detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)2.62807126
136glycerophospholipid catabolic process (GO:0046475)2.62196315
137reflex (GO:0060004)2.61195308
138cyclic nucleotide catabolic process (GO:0009214)2.60120565
139multicellular organismal signaling (GO:0035637)2.59829171
140cAMP catabolic process (GO:0006198)2.59120592
141potassium ion transport (GO:0006813)2.56442825
142adult walking behavior (GO:0007628)2.56272002
143detection of light stimulus involved in sensory perception (GO:0050962)2.55179938
144detection of light stimulus involved in visual perception (GO:0050908)2.55179938
145axoneme assembly (GO:0035082)2.54965772
146atrial cardiac muscle cell action potential (GO:0086014)2.53586830
147regulation of microtubule-based movement (GO:0060632)2.53037821
148potassium ion import (GO:0010107)2.50384565

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.22411461
2* REST_21632747_ChIP-Seq_MESCs_Mouse3.10487213
3EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.79792408
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.75137183
5* RARB_27405468_Chip-Seq_BRAIN_Mouse2.66824134
6SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.63113343
7REST_18959480_ChIP-ChIP_MESCs_Mouse2.62325579
8GBX2_23144817_ChIP-Seq_PC3_Human2.61541521
9JARID2_20064375_ChIP-Seq_MESCs_Mouse2.56746979
10CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.54093384
11DROSHA_22980978_ChIP-Seq_HELA_Human2.52548487
12JARID2_20075857_ChIP-Seq_MESCs_Mouse2.47505989
13ERG_21242973_ChIP-ChIP_JURKAT_Human2.45406439
14EZH2_18974828_ChIP-Seq_MESCs_Mouse2.37078365
15RNF2_18974828_ChIP-Seq_MESCs_Mouse2.37078365
16ZFP57_27257070_Chip-Seq_ESCs_Mouse2.36673427
17SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.36568870
18MTF2_20144788_ChIP-Seq_MESCs_Mouse2.29336353
19NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.25570863
20EZH2_27304074_Chip-Seq_ESCs_Mouse2.22551343
21SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.19682300
22SUZ12_27294783_Chip-Seq_ESCs_Mouse2.18087049
23VDR_22108803_ChIP-Seq_LS180_Human2.16470296
24SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.11515196
25GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.10428697
26SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.09442652
27IKZF1_21737484_ChIP-ChIP_HCT116_Human2.08940952
28* EZH2_27294783_Chip-Seq_ESCs_Mouse2.06735099
29RNF2_27304074_Chip-Seq_ESCs_Mouse2.06506611
30TAF15_26573619_Chip-Seq_HEK293_Human1.93102922
31* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.90682980
32POU3F2_20337985_ChIP-ChIP_501MEL_Human1.88846233
33EED_16625203_ChIP-ChIP_MESCs_Mouse1.88557481
34TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.85160213
35FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.85115356
36P300_19829295_ChIP-Seq_ESCs_Human1.79171568
37SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.75370497
38GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.74630485
39MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.73156765
40FLI1_27457419_Chip-Seq_LIVER_Mouse1.70921516
41ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.65314838
42RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.59328898
43ZFP281_18757296_ChIP-ChIP_E14_Mouse1.58927712
44FUS_26573619_Chip-Seq_HEK293_Human1.57481389
45PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.54169344
46ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.53661805
47KDM2B_26808549_Chip-Seq_K562_Human1.51179296
48AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.49589735
49PIAS1_25552417_ChIP-Seq_VCAP_Human1.48895152
50DNAJC2_21179169_ChIP-ChIP_NT2_Human1.44836852
51BCAT_22108803_ChIP-Seq_LS180_Human1.39004263
52PCGF2_27294783_Chip-Seq_ESCs_Mouse1.38986971
53RING1B_27294783_Chip-Seq_NPCs_Mouse1.38477763
54ER_23166858_ChIP-Seq_MCF-7_Human1.37248679
55RING1B_27294783_Chip-Seq_ESCs_Mouse1.36666514
56TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.34162507
57POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.34162507
58CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.33501183
59SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.31435415
60NR3C1_21868756_ChIP-Seq_MCF10A_Human1.31348821
61MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.31113217
62ZFP281_27345836_Chip-Seq_ESCs_Mouse1.31086697
63TOP2B_26459242_ChIP-Seq_MCF-7_Human1.30955045
64TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.29424366
65TET1_21490601_ChIP-Seq_MESCs_Mouse1.28407180
66EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.28157568
67UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.27901384
68ZNF274_21170338_ChIP-Seq_K562_Hela1.27092979
69CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.25696663
70CBP_20019798_ChIP-Seq_JUKART_Human1.25454448
71IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.25454448
72AR_21572438_ChIP-Seq_LNCaP_Human1.24337872
73BMI1_23680149_ChIP-Seq_NPCS_Mouse1.23737220
74ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.22731945
75CTBP2_25329375_ChIP-Seq_LNCAP_Human1.21896315
76SALL1_21062744_ChIP-ChIP_HESCs_Human1.21435220
77CTCF_27219007_Chip-Seq_Bcells_Human1.21173296
78RUNX2_22187159_ChIP-Seq_PCA_Human1.20040353
79OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.19849428
80* TP53_22573176_ChIP-Seq_HFKS_Human1.19765417
81EWS_26573619_Chip-Seq_HEK293_Human1.18066340
82SMAD4_21799915_ChIP-Seq_A2780_Human1.17725685
83AR_19668381_ChIP-Seq_PC3_Human1.17518310
84EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.16463419
85TCF4_22108803_ChIP-Seq_LS180_Human1.16190836
86MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.15902817
87WT1_25993318_ChIP-Seq_PODOCYTE_Human1.15396166
88* OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.14668249
89SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.12840943
90PRDM14_20953172_ChIP-Seq_ESCs_Human1.11843421
91ETV2_25802403_ChIP-Seq_MESCs_Mouse1.09737521
92LXR_22292898_ChIP-Seq_THP-1_Human1.09233153
93STAT3_23295773_ChIP-Seq_U87_Human1.08911176
94SMAD4_21741376_ChIP-Seq_EPCs_Human1.08456410
95SOX2_21211035_ChIP-Seq_LN229_Gbm1.08192082
96CTBP1_25329375_ChIP-Seq_LNCAP_Human1.07713512
97SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.07463101
98RNF2_27304074_Chip-Seq_NSC_Mouse1.06403872
99NANOG_18555785_Chip-Seq_ESCs_Mouse1.06064601
100SOX2_19829295_ChIP-Seq_ESCs_Human1.05520131
101NANOG_19829295_ChIP-Seq_ESCs_Human1.05520131
102SUZ12_27294783_Chip-Seq_NPCs_Mouse1.05152229
103TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.04805709
104FLI1_21867929_ChIP-Seq_TH2_Mouse1.04614749
105TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.04356495
106KLF5_20875108_ChIP-Seq_MESCs_Mouse1.03471369
107PCGF2_27294783_Chip-Seq_NPCs_Mouse1.03252229
108GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.01812162
109GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.01399746
110P53_22127205_ChIP-Seq_FIBROBLAST_Human1.00417660
111YAP1_20516196_ChIP-Seq_MESCs_Mouse0.99233773
112EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.98851320
113EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.98821878
114TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.98203822
115PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.98181251
116TP53_20018659_ChIP-ChIP_R1E_Mouse0.97392006
117* SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.96639039
118NR3C1_23031785_ChIP-Seq_PC12_Mouse0.93550116
119SMC4_20622854_ChIP-Seq_HELA_Human0.91787101
120MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.91195503
121SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.90249823
122TCF4_23295773_ChIP-Seq_U87_Human0.89719699
123SMAD3_21741376_ChIP-Seq_ESCs_Human0.89642513
124CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.89565843
125RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.89161116
126OCT4_19829295_ChIP-Seq_ESCs_Human0.88939261
127WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.88496441
128STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.85620920
129DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.85466995
130KDM2B_26808549_Chip-Seq_SUP-B15_Human0.84140860
131POU5F1_16518401_ChIP-PET_MESCs_Mouse0.83673280
132SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.83340965
133CBX2_27304074_Chip-Seq_ESCs_Mouse0.82858283
134PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.82056884
135* KLF4_19829295_ChIP-Seq_ESCs_Human0.81547889
136SOX2_18358816_ChIP-ChIP_MESCs_Mouse0.81357045
137TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.80991628
138SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.79636383
139LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.79140763
140SMAD3_21741376_ChIP-Seq_HESCs_Human0.78701911
141SMAD4_21741376_ChIP-Seq_HESCs_Human0.78517103
142ZNF217_24962896_ChIP-Seq_MCF-7_Human0.77882515
143AR_25329375_ChIP-Seq_VCAP_Human0.77496731
144PRDM14_21183938_ChIP-Seq_MESCs_Mouse0.77383685
145SMAD3_21741376_ChIP-Seq_EPCs_Human0.77217325
146TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.76501795
147TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.76236747
148IGF1R_20145208_ChIP-Seq_DFB_Human0.76020431

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.70766506
2MP0003635_abnormal_synaptic_transmissio3.73022812
3MP0003880_abnormal_central_pattern3.64508434
4MP0004270_analgesia3.41234686
5MP0009046_muscle_twitch3.12514641
6MP0002063_abnormal_learning/memory/cond2.98605891
7MP0009745_abnormal_behavioral_response2.96293877
8MP0002064_seizures2.93459989
9MP0003283_abnormal_digestive_organ2.92546525
10MP0005423_abnormal_somatic_nervous2.81053740
11MP0002572_abnormal_emotion/affect_behav2.71893313
12MP0005645_abnormal_hypothalamus_physiol2.57372873
13MP0001968_abnormal_touch/_nociception2.49275805
14MP0002272_abnormal_nervous_system2.45183137
15MP0002734_abnormal_mechanical_nocicepti2.39206337
16MP0002733_abnormal_thermal_nociception2.33215290
17MP0002909_abnormal_adrenal_gland2.27913687
18MP0002822_catalepsy2.18503913
19MP0001486_abnormal_startle_reflex2.12435826
20MP0001501_abnormal_sleep_pattern2.11641673
21MP0001970_abnormal_pain_threshold2.09330064
22MP0005646_abnormal_pituitary_gland2.05487170
23MP0009780_abnormal_chondrocyte_physiolo1.93878514
24MP0003122_maternal_imprinting1.91890799
25MP0008569_lethality_at_weaning1.82911346
26MP0002067_abnormal_sensory_capabilities1.82155072
27MP0002837_dystrophic_cardiac_calcinosis1.81314453
28MP0001440_abnormal_grooming_behavior1.80814418
29MP0000955_abnormal_spinal_cord1.80278216
30MP0003787_abnormal_imprinting1.75678557
31MP0002184_abnormal_innervation1.72664102
32MP0004811_abnormal_neuron_physiology1.71564345
33MP0002736_abnormal_nociception_after1.71498948
34MP0003195_calcinosis1.70706048
35MP0002557_abnormal_social/conspecific_i1.66136682
36MP0002735_abnormal_chemical_nociception1.62888314
37MP0001502_abnormal_circadian_rhythm1.60991549
38MP0004858_abnormal_nervous_system1.60887890
39MP0004924_abnormal_behavior1.60830736
40MP0005386_behavior/neurological_phenoty1.60830736
41MP0002876_abnormal_thyroid_physiology1.53356573
42MP0004142_abnormal_muscle_tone1.51233523
43MP0000778_abnormal_nervous_system1.47311552
44MP0006072_abnormal_retinal_apoptosis1.46541079
45MP0005171_absent_coat_pigmentation1.46079413
46MP0004885_abnormal_endolymph1.44737184
47MP0000013_abnormal_adipose_tissue1.44179228
48MP0004233_abnormal_muscle_weight1.43755276
49MP0002066_abnormal_motor_capabilities/c1.41931821
50MP0003633_abnormal_nervous_system1.38745599
51MP0006276_abnormal_autonomic_nervous1.38397373
52MP0003329_amyloid_beta_deposits1.38289528
53MP0002882_abnormal_neuron_morphology1.37770212
54MP0000569_abnormal_digit_pigmentation1.37580723
55MP0003172_abnormal_lysosome_physiology1.34520667
56MP0003879_abnormal_hair_cell1.33168544
57MP0001986_abnormal_taste_sensitivity1.31393354
58MP0002653_abnormal_ependyma_morphology1.22439216
59MP0010386_abnormal_urinary_bladder1.21050291
60MP0004145_abnormal_muscle_electrophysio1.12720426
61MP0003631_nervous_system_phenotype1.10879959
62MP0008877_abnormal_DNA_methylation1.08009342
63MP0004147_increased_porphyrin_level1.07945502
64MP0002152_abnormal_brain_morphology1.06909961
65MP0001984_abnormal_olfaction1.06652050
66MP0008961_abnormal_basal_metabolism1.05175673
67MP0006292_abnormal_olfactory_placode1.05064868
68MP0002638_abnormal_pupillary_reflex1.00735278
69MP0000631_abnormal_neuroendocrine_gland0.99462909
70MP0002229_neurodegeneration0.98065200
71MP0004043_abnormal_pH_regulation0.98007077
72MP0001905_abnormal_dopamine_level0.97722228
73MP0005379_endocrine/exocrine_gland_phen0.97292087
74MP0002069_abnormal_eating/drinking_beha0.96153338
75MP0008875_abnormal_xenobiotic_pharmacok0.96001794
76MP0000639_abnormal_adrenal_gland0.95490437
77MP0002102_abnormal_ear_morphology0.94659846
78MP0000427_abnormal_hair_cycle0.93934805
79MP0001529_abnormal_vocalization0.93213675
80MP0003634_abnormal_glial_cell0.92682006
81MP0004215_abnormal_myocardial_fiber0.91191746
82MP0004133_heterotaxia0.90380298
83MP0003119_abnormal_digestive_system0.87232548
84MP0002928_abnormal_bile_duct0.84126568
85MP0002693_abnormal_pancreas_physiology0.81517286
86MP0003890_abnormal_embryonic-extraembry0.81381496
87MP0008872_abnormal_physiological_respon0.80424452
88MP0004085_abnormal_heartbeat0.79311417
89MP0001485_abnormal_pinna_reflex0.77766370
90MP0008874_decreased_physiological_sensi0.77407776
91MP0001944_abnormal_pancreas_morphology0.76545343
92MP0002163_abnormal_gland_morphology0.76422249
93MP0005535_abnormal_body_temperature0.75958295
94MP0003690_abnormal_glial_cell0.75938497
95MP0000026_abnormal_inner_ear0.75698922
96MP0005167_abnormal_blood-brain_barrier0.75487947
97MP0003045_fibrosis0.74812902
98MP0005195_abnormal_posterior_eye0.74299250
99MP0003137_abnormal_impulse_conducting0.74039527
100MP0003632_abnormal_nervous_system0.73702675
101MP0002160_abnormal_reproductive_system0.73450327
102MP0003123_paternal_imprinting0.73138716
103MP0003136_yellow_coat_color0.73035813
104MP0001963_abnormal_hearing_physiology0.72185236
105MP0003075_altered_response_to0.71255430
106MP0005253_abnormal_eye_physiology0.71251604
107MP0002752_abnormal_somatic_nervous0.70535843
108MP0002938_white_spotting0.69441830
109MP0002751_abnormal_autonomic_nervous0.69437301
110MP0001188_hyperpigmentation0.68430644
111MP0002090_abnormal_vision0.68365215
112MP0000462_abnormal_digestive_system0.68252999
113MP0005551_abnormal_eye_electrophysiolog0.67904271
114MP0003953_abnormal_hormone_level0.67068707
115MP0003121_genomic_imprinting0.65529730
116MP0000751_myopathy0.64848825
117MP0004130_abnormal_muscle_cell0.64380316
118MP0001943_abnormal_respiration0.63521598
119MP0010769_abnormal_survival0.62990097
120MP0010768_mortality/aging0.61646023
121MP0005394_taste/olfaction_phenotype0.61169709
122MP0005499_abnormal_olfactory_system0.61169709
123MP0004742_abnormal_vestibular_system0.61134290

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)5.97651002
2Myokymia (HP:0002411)5.90283455
3Visual hallucinations (HP:0002367)5.18847761
4Focal seizures (HP:0007359)4.56555036
5Atonic seizures (HP:0010819)4.42173622
6Epileptic encephalopathy (HP:0200134)4.18440881
7Febrile seizures (HP:0002373)4.10092724
8Hyperventilation (HP:0002883)3.91941038
9Elevated circulating parathyroid hormone (PTH) level (HP:0003165)3.71490169
10Absence seizures (HP:0002121)3.68441032
11Action tremor (HP:0002345)3.67960170
12Progressive cerebellar ataxia (HP:0002073)3.65381229
13Pancreatic cysts (HP:0001737)3.60477203
14Abnormality of midbrain morphology (HP:0002418)3.49584700
15Molar tooth sign on MRI (HP:0002419)3.49584700
16Pancreatic fibrosis (HP:0100732)3.45011141
17Annular pancreas (HP:0001734)3.41739698
18True hermaphroditism (HP:0010459)3.38312314
19Generalized tonic-clonic seizures (HP:0002069)3.25525504
20Dialeptic seizures (HP:0011146)3.25042451
21Nephronophthisis (HP:0000090)3.21742495
22Supranuclear gaze palsy (HP:0000605)3.16387870
23Ankle clonus (HP:0011448)3.15573813
24Congenital stationary night blindness (HP:0007642)3.07399856
25Papilledema (HP:0001085)3.05564228
26Depression (HP:0000716)2.96305978
27Dysdiadochokinesis (HP:0002075)2.96016741
28Medial flaring of the eyebrow (HP:0010747)2.85894256
29Abnormality of the lower motor neuron (HP:0002366)2.81333246
30Type II lissencephaly (HP:0007260)2.75228707
31Pheochromocytoma (HP:0002666)2.74163595
32Abnormality of the renal medulla (HP:0100957)2.72921871
33Turricephaly (HP:0000262)2.68853430
34Agitation (HP:0000713)2.68327476
35Abnormality of the renal cortex (HP:0011035)2.65815700
36Anxiety (HP:0000739)2.65373823
37Gaze-evoked nystagmus (HP:0000640)2.65294692
38Cystic liver disease (HP:0006706)2.64675483
39Dysmetria (HP:0001310)2.64006852
40Abnormal eating behavior (HP:0100738)2.63763497
41Hypercortisolism (HP:0001578)2.63542976
42Postural instability (HP:0002172)2.62560809
43Gait imbalance (HP:0002141)2.61371451
44Impaired smooth pursuit (HP:0007772)2.59271638
45Broad-based gait (HP:0002136)2.56858651
46Abnormal drinking behavior (HP:0030082)2.56120454
47Polydipsia (HP:0001959)2.56120454
48Failure to thrive in infancy (HP:0001531)2.55056144
49EEG with generalized epileptiform discharges (HP:0011198)2.49997963
50Epileptiform EEG discharges (HP:0011182)2.49444320
51Hemiparesis (HP:0001269)2.49419579
52Limb dystonia (HP:0002451)2.49227855
53Poor eye contact (HP:0000817)2.47847629
54Genetic anticipation (HP:0003743)2.47105947
55Ketoacidosis (HP:0001993)2.46591685
56Intention tremor (HP:0002080)2.45212807
57Hypsarrhythmia (HP:0002521)2.44834713
58Ventricular fibrillation (HP:0001663)2.44298006
59Urinary bladder sphincter dysfunction (HP:0002839)2.36080988
60Abnormality of calcium-phosphate metabolism (HP:0100530)2.33555388
61Truncal ataxia (HP:0002078)2.33064051
62Absent speech (HP:0001344)2.32986195
63Fetal akinesia sequence (HP:0001989)2.30249731
64Mutism (HP:0002300)2.28645563
65Hyperparathyroidism (HP:0000843)2.27335947
66Abnormal social behavior (HP:0012433)2.26497447
67Impaired social interactions (HP:0000735)2.26497447
68Amblyopia (HP:0000646)2.25669448
69Impaired vibration sensation in the lower limbs (HP:0002166)2.24805674
70Attenuation of retinal blood vessels (HP:0007843)2.24006559
71Inability to walk (HP:0002540)2.21604021
72Hemiplegia (HP:0002301)2.21302997
73Congenital primary aphakia (HP:0007707)2.21154248
74Neuroendocrine neoplasm (HP:0100634)2.21126627
75Chronic hepatic failure (HP:0100626)2.19423556
76Bradykinesia (HP:0002067)2.19407215
77Large for gestational age (HP:0001520)2.18198995
78Postural tremor (HP:0002174)2.17766153
79Abnormal rod and cone electroretinograms (HP:0008323)2.17243092
80Menstrual irregularities (HP:0000858)2.16593991
81Protruding tongue (HP:0010808)2.16006920
82Hypothermia (HP:0002045)2.15542770
83Growth hormone excess (HP:0000845)2.14710317
84Abnormality of ocular smooth pursuit (HP:0000617)2.12830430
85Spastic gait (HP:0002064)2.12596143
86Intestinal atresia (HP:0011100)2.11617995
87Clonus (HP:0002169)2.11406796
88Status epilepticus (HP:0002133)2.11179166
89Tubular atrophy (HP:0000092)2.10791240
90Lissencephaly (HP:0001339)2.10122043
91Torticollis (HP:0000473)2.07941859
92Optic nerve hypoplasia (HP:0000609)2.05347834
93Ketosis (HP:0001946)2.03787092
94Obstructive sleep apnea (HP:0002870)2.02714028
95Nephrogenic diabetes insipidus (HP:0009806)2.02507114
96Pendular nystagmus (HP:0012043)2.01568586
97Urinary glycosaminoglycan excretion (HP:0003541)2.01154247
98Mucopolysacchariduria (HP:0008155)2.01154247
99Spastic tetraplegia (HP:0002510)1.99457205
100Anteriorly placed anus (HP:0001545)1.98947678
101Sclerocornea (HP:0000647)1.98668775
102Polyuria (HP:0000103)1.98311887
103Renal cortical cysts (HP:0000803)1.96267330
104Alacrima (HP:0000522)1.96168624
105Scanning speech (HP:0002168)1.96031956
106Neoplasm of the heart (HP:0100544)1.95548136
107Abolished electroretinogram (ERG) (HP:0000550)1.95294845
108Abnormality of polysaccharide metabolism (HP:0011012)1.94361987
109Abnormality of glycosaminoglycan metabolism (HP:0004371)1.94361987
110Abnormality of mucopolysaccharide metabolism (HP:0011020)1.94361987
111Short chin (HP:0000331)1.93800625
112Narrow nasal bridge (HP:0000446)1.93170704
113Insomnia (HP:0100785)1.92934513
114Progressive inability to walk (HP:0002505)1.92377709
115Abnormality of the labia minora (HP:0012880)1.91019269
116Hypomagnesemia (HP:0002917)1.90311989
117Pancreatic islet-cell hyperplasia (HP:0004510)1.89985055
118Focal dystonia (HP:0004373)1.89439114
119Abnormality of the periventricular white matter (HP:0002518)1.89155829
120Genital tract atresia (HP:0001827)1.89052991
121Diplopia (HP:0000651)1.88341351
122Abnormality of binocular vision (HP:0011514)1.88341351
123Excessive salivation (HP:0003781)1.87022816
124Drooling (HP:0002307)1.87022816
125Hyperinsulinemic hypoglycemia (HP:0000825)1.86642953
126Abnormal EKG (HP:0003115)1.86544791
127Vaginal atresia (HP:0000148)1.86532073
128Dysautonomia (HP:0002459)1.85719721
129Anencephaly (HP:0002323)1.84811161
130Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.83350632
131Male infertility (HP:0003251)1.83016709
132Orthostatic hypotension (HP:0001278)1.82887381
133Prolonged QT interval (HP:0001657)1.82844243
134Specific learning disability (HP:0001328)1.81816292
135Pachygyria (HP:0001302)1.81411734
136Furrowed tongue (HP:0000221)1.81091191
137Generalized myoclonic seizures (HP:0002123)1.80059857
138Concave nail (HP:0001598)1.79632589
139Dynein arm defect of respiratory motile cilia (HP:0012255)1.79389850
140Absent/shortened dynein arms (HP:0200106)1.79389850
141Neurofibrillary tangles (HP:0002185)1.78705144
142Megalencephaly (HP:0001355)1.77836981
143Dysostosis multiplex (HP:0000943)1.76932281
144Hypoventilation (HP:0002791)1.76913641
145Lower limb muscle weakness (HP:0007340)1.76571022
146Dysmetric saccades (HP:0000641)1.75245526
147Polyphagia (HP:0002591)1.74543928
148Male pseudohermaphroditism (HP:0000037)1.73681191
149Psychosis (HP:0000709)1.73634390
150Abnormal respiratory motile cilium morphology (HP:0005938)1.73464097
151Abnormal respiratory epithelium morphology (HP:0012253)1.73464097
152Cortical visual impairment (HP:0100704)1.72719387
153Hypoglycemic coma (HP:0001325)1.72171315
154Aplasia/Hypoplasia of the tongue (HP:0010295)1.71228979
155Severe muscular hypotonia (HP:0006829)1.69770374
156Oligodactyly (hands) (HP:0001180)1.69513601
157Tachypnea (HP:0002789)1.69461077
158Abnormality of macular pigmentation (HP:0008002)1.68210145
159Decreased central vision (HP:0007663)1.67974963
160Muscular hypotonia of the trunk (HP:0008936)1.67580221
161Occipital encephalocele (HP:0002085)1.67551007

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK5.01635045
2NTRK34.10745542
3MAP3K93.84548566
4MAPK152.72482658
5EPHA42.61305745
6UHMK12.61141701
7ICK2.44665486
8MARK12.42056713
9MAP3K42.37964263
10PINK12.28599895
11PRKD32.20973356
12NTRK12.15585256
13DAPK12.12290557
14NTRK22.11721395
15TYRO32.10625026
16PAK62.04890065
17ADRBK22.04560830
18MINK12.03198601
19MAP4K21.98991124
20DDR21.98305819
21MAP3K61.93645955
22MAP2K71.88612426
23DAPK21.81192790
24GRK11.73946718
25WNK41.63727791
26KSR21.62541949
27BMPR1B1.61909795
28CAMKK11.48988671
29PRPF4B1.43095742
30STK381.38253551
31PRKD21.36556625
32CDC42BPA1.36336135
33MAP2K41.35474373
34CDK51.34078946
35MAP3K121.31252245
36STK391.24232140
37FGFR21.24206786
38ACVR1B1.23182360
39PHKG11.22456133
40PHKG21.22456133
41MAP3K21.19130181
42TAOK31.17766116
43CASK1.15363402
44CDK191.14740558
45GRK51.14479246
46PDGFRA1.14471245
47AKT31.13920221
48DYRK21.12744837
49LATS21.11658273
50HIPK21.10600927
51CAMKK21.10232408
52ARAF1.09544858
53TNIK1.08152140
54FGR1.06583767
55INSRR1.03623736
56ZAK1.02405693
57WNK30.98234809
58PRKCG0.96751077
59MATK0.96469317
60ALK0.95407634
61CAMK2A0.94416838
62PRKCH0.93491718
63SIK20.92664208
64MAP3K110.92269351
65NUAK10.90890309
66MAPK130.89242691
67CAMK2B0.86794460
68MAP3K10.84907821
69TAOK10.84109212
70TNK20.82055888
71BMX0.79515482
72PTK2B0.79468622
73CDK150.78631304
74MARK20.78076852
75STK110.77296991
76KSR10.77270425
77CDK180.77067500
78CSNK1G30.76625029
79CSNK1G10.76294627
80PNCK0.72111922
81SGK2230.71328373
82SGK4940.71328373
83MAP2K60.71299517
84CDK11A0.70165285
85CAMK10.69737072
86CDK140.69298134
87SGK10.68436876
88DYRK1B0.68248090
89PKN10.67971176
90ADRBK10.66725053
91SGK30.66413539
92MKNK20.65744333
93CAMK2G0.65470781
94PAK30.64742294
95RAF10.64719408
96CAMK2D0.61893253
97SCYL20.61367964
98MAP3K130.60086373
99CSNK1A1L0.59265571
100PLK20.58526564
101WNK10.57878306
102RET0.57244185
103SGK20.56508609
104TLK10.56094601
105MAPK100.56090931
106FES0.56037945
107BCR0.55366390
108RIPK10.54787835
109PRKACA0.54495003
110RPS6KA30.54473422
111TIE10.54068527
112CSNK1G20.52563944
113LIMK10.52333579
114STK38L0.52040894
115PRKAA10.49310147
116TXK0.47191796
117CAMK1G0.46285520
118BRSK10.46249072
119NEK60.46112264
120PRKCA0.44628574
121CSNK1A10.43359064
122DYRK1A0.42882246
123PRKCZ0.42568313
124EPHA30.42537990
125OXSR10.42327427
126PRKG10.42262190
127RIPK40.41073381
128LMTK20.40733600
129PRKCQ0.40651510
130ERBB30.39820183
131RPS6KB10.39209839
132TRIM280.39085057
133CSNK1D0.38802751
134FER0.38260945
135CAMK40.38167495
136PTK20.38048545
137PRKCI0.36046240
138YES10.35246957
139ERBB20.33536167
140PRKCE0.32972630
141BCKDK0.32602972
142MUSK0.29804185
143CSNK1E0.29632697
144PRKACB0.25687073
145PRKCB0.25351754

Predicted pathways (KEGG)

RankGene SetZ-score
1Synaptic vesicle cycle_Homo sapiens_hsa047213.40498146
2Nicotine addiction_Homo sapiens_hsa050333.37901918
3GABAergic synapse_Homo sapiens_hsa047272.82607691
4Insulin secretion_Homo sapiens_hsa049112.67646233
5Olfactory transduction_Homo sapiens_hsa047402.54640217
6Amphetamine addiction_Homo sapiens_hsa050312.51551114
7Circadian entrainment_Homo sapiens_hsa047132.50888751
8Glutamatergic synapse_Homo sapiens_hsa047242.38049000
9Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.37814088
10Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.36647200
11Morphine addiction_Homo sapiens_hsa050322.33797437
12Long-term potentiation_Homo sapiens_hsa047202.29118710
13Dopaminergic synapse_Homo sapiens_hsa047282.10012054
14Butanoate metabolism_Homo sapiens_hsa006502.08511120
15Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.03359854
16Cocaine addiction_Homo sapiens_hsa050301.94789883
17Maturity onset diabetes of the young_Homo sapiens_hsa049501.92574469
18Salivary secretion_Homo sapiens_hsa049701.90616020
19Taste transduction_Homo sapiens_hsa047421.89035133
20Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.86378554
21Aldosterone synthesis and secretion_Homo sapiens_hsa049251.78044143
22Cholinergic synapse_Homo sapiens_hsa047251.74979275
23Gastric acid secretion_Homo sapiens_hsa049711.71579475
24Long-term depression_Homo sapiens_hsa047301.67163607
25Linoleic acid metabolism_Homo sapiens_hsa005911.64501504
26Type II diabetes mellitus_Homo sapiens_hsa049301.62355083
27Serotonergic synapse_Homo sapiens_hsa047261.62192524
28alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.56320723
29Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.47749677
30Gap junction_Homo sapiens_hsa045401.46453337
31GnRH signaling pathway_Homo sapiens_hsa049121.41906329
32Oxidative phosphorylation_Homo sapiens_hsa001901.41668590
33Renin secretion_Homo sapiens_hsa049241.40103350
34Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.39667664
35Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.35410821
36Circadian rhythm_Homo sapiens_hsa047101.34916549
37Oxytocin signaling pathway_Homo sapiens_hsa049211.34470403
38Ether lipid metabolism_Homo sapiens_hsa005651.34174443
39Collecting duct acid secretion_Homo sapiens_hsa049661.30533698
40Estrogen signaling pathway_Homo sapiens_hsa049151.27775944
41Calcium signaling pathway_Homo sapiens_hsa040201.27629485
42Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.27170271
43Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.26981556
44Fatty acid biosynthesis_Homo sapiens_hsa000611.26507805
45Tryptophan metabolism_Homo sapiens_hsa003801.24811098
46Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.23639535
47Vibrio cholerae infection_Homo sapiens_hsa051101.23336987
48cAMP signaling pathway_Homo sapiens_hsa040241.19754807
49Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.13457311
50Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.09554721
51Phosphatidylinositol signaling system_Homo sapiens_hsa040701.09032530
52Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.08416791
53Dorso-ventral axis formation_Homo sapiens_hsa043201.05696676
54Oocyte meiosis_Homo sapiens_hsa041141.04642229
55Pancreatic secretion_Homo sapiens_hsa049721.03901143
56ErbB signaling pathway_Homo sapiens_hsa040121.01781939
57Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.00119049
58Melanogenesis_Homo sapiens_hsa049160.99996852
59Type I diabetes mellitus_Homo sapiens_hsa049400.99418391
60Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.98767534
61Selenocompound metabolism_Homo sapiens_hsa004500.98609702
62mTOR signaling pathway_Homo sapiens_hsa041500.98042092
63Protein export_Homo sapiens_hsa030600.97907776
64Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.94423591
65Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.94147220
66Vitamin B6 metabolism_Homo sapiens_hsa007500.94054727
67ABC transporters_Homo sapiens_hsa020100.92609707
68Thyroid hormone synthesis_Homo sapiens_hsa049180.90758507
69beta-Alanine metabolism_Homo sapiens_hsa004100.89279562
70Parkinsons disease_Homo sapiens_hsa050120.89086936
71Carbohydrate digestion and absorption_Homo sapiens_hsa049730.87459397
72Alzheimers disease_Homo sapiens_hsa050100.84676644
73Nitrogen metabolism_Homo sapiens_hsa009100.84661796
74Vascular smooth muscle contraction_Homo sapiens_hsa042700.84264771
75cGMP-PKG signaling pathway_Homo sapiens_hsa040220.84222899
76Longevity regulating pathway - mammal_Homo sapiens_hsa042110.80810142
77Glioma_Homo sapiens_hsa052140.80201574
78Propanoate metabolism_Homo sapiens_hsa006400.76653223
79Caffeine metabolism_Homo sapiens_hsa002320.75204511
80Axon guidance_Homo sapiens_hsa043600.74748705
81Choline metabolism in cancer_Homo sapiens_hsa052310.73879526
82Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.73499502
83MAPK signaling pathway_Homo sapiens_hsa040100.73016926
84Hedgehog signaling pathway_Homo sapiens_hsa043400.71227119
85Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.71175621
86Primary bile acid biosynthesis_Homo sapiens_hsa001200.68794487
87Phospholipase D signaling pathway_Homo sapiens_hsa040720.68727216
88Peroxisome_Homo sapiens_hsa041460.66965806
89Wnt signaling pathway_Homo sapiens_hsa043100.66180406
90Glucagon signaling pathway_Homo sapiens_hsa049220.65871404
91Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.65817789
92Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.64877337
93Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.64042412
94Histidine metabolism_Homo sapiens_hsa003400.62954303
95Cardiac muscle contraction_Homo sapiens_hsa042600.57647168
96Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.57509180
97Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.56304047
98VEGF signaling pathway_Homo sapiens_hsa043700.55387372
99Insulin signaling pathway_Homo sapiens_hsa049100.54733494
100Endocytosis_Homo sapiens_hsa041440.54487460
101Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.52260615
102Alcoholism_Homo sapiens_hsa050340.51533542
103Thyroid hormone signaling pathway_Homo sapiens_hsa049190.51499248
104Arachidonic acid metabolism_Homo sapiens_hsa005900.50832853
105Ras signaling pathway_Homo sapiens_hsa040140.50776119
106Huntingtons disease_Homo sapiens_hsa050160.50774856
107Steroid hormone biosynthesis_Homo sapiens_hsa001400.49600751
108Prion diseases_Homo sapiens_hsa050200.47921201
109Neurotrophin signaling pathway_Homo sapiens_hsa047220.47587766
110Ovarian steroidogenesis_Homo sapiens_hsa049130.47472086
111Bile secretion_Homo sapiens_hsa049760.47293442
112Dilated cardiomyopathy_Homo sapiens_hsa054140.46682760
113Inositol phosphate metabolism_Homo sapiens_hsa005620.46626497
114Glycerolipid metabolism_Homo sapiens_hsa005610.46224865
115Hippo signaling pathway_Homo sapiens_hsa043900.43559349
116Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.43125561
117Phototransduction_Homo sapiens_hsa047440.41685147
118Endometrial cancer_Homo sapiens_hsa052130.41155600
119Rap1 signaling pathway_Homo sapiens_hsa040150.39753078
120Sphingolipid signaling pathway_Homo sapiens_hsa040710.39466580
121Arginine and proline metabolism_Homo sapiens_hsa003300.39455136
122Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.38326428
123Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.36863141
124Glycerophospholipid metabolism_Homo sapiens_hsa005640.36805384
125SNARE interactions in vesicular transport_Homo sapiens_hsa041300.36801657
126Fatty acid metabolism_Homo sapiens_hsa012120.36449102
127Basal transcription factors_Homo sapiens_hsa030220.35149538
128Prolactin signaling pathway_Homo sapiens_hsa049170.33538280
129Sulfur metabolism_Homo sapiens_hsa009200.33512708
130Chemical carcinogenesis_Homo sapiens_hsa052040.32301710
131Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.32226449
132Metabolic pathways_Homo sapiens_hsa011000.30084429
133Tight junction_Homo sapiens_hsa045300.29661689
134Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.27851086
135Mineral absorption_Homo sapiens_hsa049780.26883099
136Regulation of autophagy_Homo sapiens_hsa041400.26772322
137Lysosome_Homo sapiens_hsa041420.26588607

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