SGTB

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)6.09498847
2synaptic vesicle exocytosis (GO:0016079)5.72345387
3synaptic vesicle maturation (GO:0016188)5.68483351
4positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.55498054
5vocalization behavior (GO:0071625)5.48459112
6glutamate secretion (GO:0014047)5.46295246
7positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.40478999
8locomotory exploration behavior (GO:0035641)5.31663548
9regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.15341797
10regulation of synaptic vesicle exocytosis (GO:2000300)5.06783757
11synaptic vesicle docking involved in exocytosis (GO:0016081)4.94336468
12regulation of glutamate receptor signaling pathway (GO:1900449)4.82711577
13protein localization to synapse (GO:0035418)4.82672796
14neuron cell-cell adhesion (GO:0007158)4.74732533
15neuronal action potential propagation (GO:0019227)4.65716794
16ionotropic glutamate receptor signaling pathway (GO:0035235)4.56745339
17regulation of synaptic vesicle transport (GO:1902803)4.51960809
18neurotransmitter secretion (GO:0007269)4.46860638
19regulation of long-term neuronal synaptic plasticity (GO:0048169)4.41338414
20exploration behavior (GO:0035640)4.35410159
21regulation of neuronal synaptic plasticity (GO:0048168)4.32846094
22regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.26722568
23negative regulation of interleukin-12 production (GO:0032695)4.19708039
24neuron-neuron synaptic transmission (GO:0007270)4.14724546
25synaptic transmission, glutamatergic (GO:0035249)4.14321682
26glutamate receptor signaling pathway (GO:0007215)4.14286894
27regulation of synapse structural plasticity (GO:0051823)4.00903602
28layer formation in cerebral cortex (GO:0021819)3.98762159
29neurotransmitter-gated ion channel clustering (GO:0072578)3.96377728
30dendritic spine morphogenesis (GO:0060997)3.90876444
31regulation of excitatory postsynaptic membrane potential (GO:0060079)3.88433491
32positive regulation of heat generation (GO:0031652)3.81357011
33positive regulation of membrane potential (GO:0045838)3.74765867
34long-term memory (GO:0007616)3.74065993
35regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.71920093
36gamma-aminobutyric acid transport (GO:0015812)3.71760887
37membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.71749812
38regulation of postsynaptic membrane potential (GO:0060078)3.71273169
39neurotransmitter transport (GO:0006836)3.68924781
40regulation of synaptic plasticity (GO:0048167)3.65258011
41proline transport (GO:0015824)3.64929137
42long-term synaptic potentiation (GO:0060291)3.62973900
43neuron recognition (GO:0008038)3.61519518
44response to histamine (GO:0034776)3.60806498
45gamma-aminobutyric acid signaling pathway (GO:0007214)3.59514400
46negative regulation of synaptic transmission, GABAergic (GO:0032229)3.57480102
47positive regulation of synapse maturation (GO:0090129)3.55750146
48synaptic vesicle endocytosis (GO:0048488)3.51149265
49regulation of dendritic spine morphogenesis (GO:0061001)3.50300409
50activation of protein kinase A activity (GO:0034199)3.50186508
51cellular potassium ion homeostasis (GO:0030007)3.47835069
52regulation of neurotransmitter secretion (GO:0046928)3.47491685
53positive regulation of gamma-delta T cell activation (GO:0046645)3.47108313
54regulation of fever generation (GO:0031620)3.41051800
55positive regulation of neurotransmitter transport (GO:0051590)3.40464568
56regulation of neurotransmitter levels (GO:0001505)3.40071630
57regulation of synaptic transmission, glutamatergic (GO:0051966)3.37708537
58behavioral response to cocaine (GO:0048148)3.37240109
59axonal fasciculation (GO:0007413)3.35367504
60positive regulation of neurotransmitter secretion (GO:0001956)3.34556465
61transmission of nerve impulse (GO:0019226)3.33132349
62presynaptic membrane assembly (GO:0097105)3.32749137
63postsynaptic membrane organization (GO:0001941)3.32551584
64cerebellar Purkinje cell differentiation (GO:0021702)3.32291096
65G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.28579516
66regulation of vesicle fusion (GO:0031338)3.28157569
67regulation of neurotransmitter transport (GO:0051588)3.25982057
68positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.25379764
69positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.24634295
70negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.21260767
71negative regulation of cell killing (GO:0031342)3.21260767
72L-amino acid import (GO:0043092)3.20222220
73regulation of heat generation (GO:0031650)3.18191663
74neuromuscular process controlling balance (GO:0050885)3.16904958
75positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.15686865
76membrane depolarization (GO:0051899)3.15543320
77membrane hyperpolarization (GO:0060081)3.14949420
78innervation (GO:0060384)3.14228263
79auditory behavior (GO:0031223)3.13507610
80prepulse inhibition (GO:0060134)3.12493094
81presynaptic membrane organization (GO:0097090)3.12177480
82vesicle transport along microtubule (GO:0047496)3.11608486
83behavioral fear response (GO:0001662)3.11184932
84behavioral defense response (GO:0002209)3.11184932
85negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.10700439
86positive regulation of synaptic transmission, GABAergic (GO:0032230)3.09188868
87learning (GO:0007612)3.07463210
88regulation of glutamate secretion (GO:0014048)3.06247612
89intraspecies interaction between organisms (GO:0051703)3.06140447
90social behavior (GO:0035176)3.06140447
91regulation of dendritic spine development (GO:0060998)3.05166904
92positive regulation of synaptic transmission (GO:0050806)3.04948541
93G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.04624622
94synaptic transmission (GO:0007268)3.04191980
95synapse assembly (GO:0007416)3.03627628
96regulation of voltage-gated calcium channel activity (GO:1901385)3.01840014
97regulation of synaptic transmission (GO:0050804)3.01007989
98neuromuscular process controlling posture (GO:0050884)3.00216891
99membrane depolarization during action potential (GO:0086010)2.98382126
100response to auditory stimulus (GO:0010996)2.97446216
101regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.97302088
102mating behavior (GO:0007617)2.97292244
103fear response (GO:0042596)2.97070528
104chemosensory behavior (GO:0007635)2.96379816
105dendritic spine organization (GO:0097061)2.94370522
106sodium ion export (GO:0071436)2.92952594
107macrophage activation involved in immune response (GO:0002281)2.92328260
108regulation of chronic inflammatory response (GO:0002676)2.89679459
109positive regulation of dendritic spine development (GO:0060999)2.89671450
110detection of calcium ion (GO:0005513)2.89666616
111regulation of vitamin D biosynthetic process (GO:0060556)2.88398960
112cellular response to ethanol (GO:0071361)2.83538726
113interferon-gamma production (GO:0032609)2.80419201
114tolerance induction (GO:0002507)2.78034562
115positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.75809827
116positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.73455222
117negative regulation of interleukin-1 beta production (GO:0032691)2.70514339
118negative regulation of T cell mediated immunity (GO:0002710)2.70266991
119negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.66267403
120positive regulation of mast cell activation (GO:0033005)2.51088292
121positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.50024938
122positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.49991330
123lipopolysaccharide-mediated signaling pathway (GO:0031663)2.48987553
124response to peptidoglycan (GO:0032494)2.46772756
125amino acid import (GO:0043090)2.46760387
126nerve growth factor signaling pathway (GO:0038180)2.44575714
127negative regulation of amino acid transport (GO:0051956)2.44331964
128cellular response to ATP (GO:0071318)2.43636535
129microglial cell activation (GO:0001774)2.42200026
130positive regulation of toll-like receptor signaling pathway (GO:0034123)2.42162591
131tryptophan catabolic process (GO:0006569)2.42013286
132indole-containing compound catabolic process (GO:0042436)2.42013286
133indolalkylamine catabolic process (GO:0046218)2.42013286
134negative regulation of interleukin-1 production (GO:0032692)2.41283673
135cellular response to interleukin-15 (GO:0071350)2.41112873
136regulation of B cell receptor signaling pathway (GO:0050855)2.40960540
137alanine transport (GO:0032328)2.40944112
138response to interleukin-15 (GO:0070672)2.40729663
139positive regulation of interleukin-1 beta secretion (GO:0050718)2.38667464
140potassium ion import (GO:0010107)2.38190943
141regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.36623513
142detection of molecule of bacterial origin (GO:0032490)2.36538780
143serotonin metabolic process (GO:0042428)2.36331853
144macrophage activation (GO:0042116)2.34504364
145oligosaccharide catabolic process (GO:0009313)2.31799950
146cAMP catabolic process (GO:0006198)2.31101902
147negative regulation of interleukin-17 production (GO:0032700)2.29587038
148protein K11-linked deubiquitination (GO:0035871)2.29095232
149activated T cell proliferation (GO:0050798)2.28276157
150positive regulation of mast cell degranulation (GO:0043306)2.27055482
151positive regulation of mast cell activation involved in immune response (GO:0033008)2.27055482
152regulation of gamma-delta T cell activation (GO:0046643)2.26728330
153phagosome maturation (GO:0090382)2.26589687
154cyclic nucleotide catabolic process (GO:0009214)2.25283861
155regulation of ARF protein signal transduction (GO:0032012)2.24883169
156regulation of interleukin-1 beta secretion (GO:0050706)2.24560432
157regulation of mononuclear cell migration (GO:0071675)2.23566169
158kynurenine metabolic process (GO:0070189)2.22916271
159myeloid leukocyte mediated immunity (GO:0002444)2.22466804

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.20174010
2GBX2_23144817_ChIP-Seq_PC3_Human3.75045788
3FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.21394993
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.18111527
5IRF8_22096565_ChIP-ChIP_GC-B_Human3.11261566
6SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.08590707
7JARID2_20064375_ChIP-Seq_MESCs_Mouse3.07479166
8STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.95154048
9IRF8_21731497_ChIP-ChIP_J774_Mouse2.84405437
10REST_21632747_ChIP-Seq_MESCs_Mouse2.74563980
11RNF2_18974828_ChIP-Seq_MESCs_Mouse2.71978554
12EZH2_18974828_ChIP-Seq_MESCs_Mouse2.71978554
13SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.66335791
14RARB_27405468_Chip-Seq_BRAIN_Mouse2.63114169
15JARID2_20075857_ChIP-Seq_MESCs_Mouse2.60179375
16SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.49256186
17MTF2_20144788_ChIP-Seq_MESCs_Mouse2.49145659
18SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.48920683
19SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.48227145
20EZH2_27304074_Chip-Seq_ESCs_Mouse2.46887669
21DROSHA_22980978_ChIP-Seq_HELA_Human2.38191465
22EED_16625203_ChIP-ChIP_MESCs_Mouse2.24932794
23IRF8_27001747_Chip-Seq_BMDM_Mouse2.22512920
24REST_18959480_ChIP-ChIP_MESCs_Mouse2.21078999
25SUZ12_27294783_Chip-Seq_ESCs_Mouse2.18845045
26RNF2_27304074_Chip-Seq_ESCs_Mouse2.12169987
27EZH2_27294783_Chip-Seq_ESCs_Mouse2.11707008
28ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.07344692
29Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.03759566
30GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.00129120
31TAF15_26573619_Chip-Seq_HEK293_Human2.00095357
32NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.99346608
33STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.97864197
34CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.94840009
35CTBP2_25329375_ChIP-Seq_LNCAP_Human1.92880007
36IKZF1_21737484_ChIP-ChIP_HCT116_Human1.92097245
37SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.81785957
38CTBP1_25329375_ChIP-Seq_LNCAP_Human1.81387650
39RUNX_20019798_ChIP-Seq_JUKART_Human1.79914098
40AR_21572438_ChIP-Seq_LNCaP_Human1.79878805
41SMAD4_21799915_ChIP-Seq_A2780_Human1.77523725
42VDR_24787735_ChIP-Seq_THP-1_Human1.74744860
43FLI1_27457419_Chip-Seq_LIVER_Mouse1.74348228
44MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.72965828
45SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.71317809
46EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.60067487
47* ZFP57_27257070_Chip-Seq_ESCs_Mouse1.57565760
48PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.52755333
49P300_19829295_ChIP-Seq_ESCs_Human1.52050013
50ERG_21242973_ChIP-ChIP_JURKAT_Human1.51024122
51PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.46445626
52PCGF2_27294783_Chip-Seq_ESCs_Mouse1.44375948
53IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.42456092
54NR3C1_23031785_ChIP-Seq_PC12_Mouse1.42455853
55ZNF274_21170338_ChIP-Seq_K562_Hela1.40916734
56IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.40590698
57SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.39271802
58SMAD3_21741376_ChIP-Seq_EPCs_Human1.38937824
59NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.35913794
60SOX2_21211035_ChIP-Seq_LN229_Gbm1.35144512
61PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.32638737
62TOP2B_26459242_ChIP-Seq_MCF-7_Human1.31929165
63BMI1_23680149_ChIP-Seq_NPCS_Mouse1.31864974
64GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.30144449
65AR_25329375_ChIP-Seq_VCAP_Human1.29443680
66MYB_21317192_ChIP-Seq_ERMYB_Mouse1.29114196
67OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.29084479
68PIAS1_25552417_ChIP-Seq_VCAP_Human1.27843762
69STAT3_23295773_ChIP-Seq_U87_Human1.27700332
70FLI1_21867929_ChIP-Seq_TH2_Mouse1.27534139
71RING1B_27294783_Chip-Seq_ESCs_Mouse1.27088186
72MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.26978716
73RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.26901683
74VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.25717001
75CBX2_27304074_Chip-Seq_ESCs_Mouse1.25348136
76RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.24526839
77TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.22954550
78IGF1R_20145208_ChIP-Seq_DFB_Human1.22489740
79EZH2_27294783_Chip-Seq_NPCs_Mouse1.22085176
80SUZ12_27294783_Chip-Seq_NPCs_Mouse1.22058331
81NANOG_18555785_Chip-Seq_ESCs_Mouse1.21450572
82SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.21426734
83FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.20129008
84CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.20041462
85AR_19668381_ChIP-Seq_PC3_Human1.19476299
86TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.17240285
87RNF2_27304074_Chip-Seq_NSC_Mouse1.16738048
88SMAD_19615063_ChIP-ChIP_OVARY_Human1.16674805
89POU3F2_20337985_ChIP-ChIP_501MEL_Human1.16261531
90FUS_26573619_Chip-Seq_HEK293_Human1.14301898
91CMYC_18555785_Chip-Seq_ESCs_Mouse1.14145526
92NRF2_20460467_ChIP-Seq_MEFs_Mouse1.13578624
93NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.13578624
94TCF4_23295773_ChIP-Seq_U87_Human1.12691921
95ZNF217_24962896_ChIP-Seq_MCF-7_Human1.11857267
96E2F1_18555785_Chip-Seq_ESCs_Mouse1.11029345
97SUZ12_18555785_Chip-Seq_ESCs_Mouse1.10723848
98ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.10580153
99AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.10522084
100MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.09893554
101TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse1.09874669
102ARNT_22903824_ChIP-Seq_MCF-7_Human1.09830557
103RING1B_27294783_Chip-Seq_NPCs_Mouse1.09730529
104P53_22127205_ChIP-Seq_FIBROBLAST_Human1.09632270
105WT1_25993318_ChIP-Seq_PODOCYTE_Human1.09552230
106P53_22387025_ChIP-Seq_ESCs_Mouse1.08774359
107KDM2B_26808549_Chip-Seq_REH_Human1.07314881
108AHR_22903824_ChIP-Seq_MCF-7_Human1.06056785
109YAP1_20516196_ChIP-Seq_MESCs_Mouse1.05523709
110EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.05273867
111NFE2_27457419_Chip-Seq_LIVER_Mouse1.04970478
112CRX_20693478_ChIP-Seq_RETINA_Mouse1.04905104
113CDX2_19796622_ChIP-Seq_MESCs_Mouse1.04684313
114RUNX2_22187159_ChIP-Seq_PCA_Human1.03923074
115PRDM14_20953172_ChIP-Seq_ESCs_Human1.03005879
116EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.02514712
117MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.02511446
118BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.01583776
119UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.01388113
120TP53_16413492_ChIP-PET_HCT116_Human1.00551188
121SMRT_27268052_Chip-Seq_Bcells_Human1.00278533
122VDR_22108803_ChIP-Seq_LS180_Human0.99650663
123SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.99454852
124GATA3_26560356_Chip-Seq_TH2_Human0.98658921
125DNAJC2_21179169_ChIP-ChIP_NT2_Human0.98348519
126NR3C1_21868756_ChIP-Seq_MCF10A_Human0.97896790
127JUN_21703547_ChIP-Seq_K562_Human0.97453000
128* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.96851375
129PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.95906344
130OCT4_21477851_ChIP-Seq_ESCs_Mouse0.95884597
131BCAT_22108803_ChIP-Seq_LS180_Human0.95679015
132SMAD3_21741376_ChIP-Seq_ESCs_Human0.95609935
133PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.95107916
134BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.94300144
135TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.92004618
136POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.92004618
137TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.89282711
138TP53_18474530_ChIP-ChIP_U2OS_Human0.89274729
139CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.89196487
140SMAD4_21741376_ChIP-Seq_HESCs_Human0.88995691
141TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.88890853
142TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.88648189
143ER_23166858_ChIP-Seq_MCF-7_Human0.88579655
144TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.88261403

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.34685880
2MP0003880_abnormal_central_pattern5.15002099
3MP0003635_abnormal_synaptic_transmissio4.17443533
4MP0004270_analgesia3.86621008
5MP0009745_abnormal_behavioral_response3.47412384
6MP0002063_abnormal_learning/memory/cond3.35724413
7MP0002064_seizures3.20487318
8MP0003303_peritoneal_inflammation3.16221717
9MP0009046_muscle_twitch3.08470945
10MP0001968_abnormal_touch/_nociception3.04621064
11MP0002822_catalepsy2.99412843
12MP0002572_abnormal_emotion/affect_behav2.87908996
13MP0002734_abnormal_mechanical_nocicepti2.65064468
14MP0002272_abnormal_nervous_system2.61465595
15MP0005423_abnormal_somatic_nervous2.60743673
16MP0001486_abnormal_startle_reflex2.58796712
17MP0001501_abnormal_sleep_pattern2.34385227
18MP0003172_abnormal_lysosome_physiology2.34321206
19MP0003724_increased_susceptibility_to2.32177563
20MP0002736_abnormal_nociception_after2.25990869
21MP0006082_CNS_inflammation2.25489743
22MP0005671_abnormal_response_to2.21238536
23MP0002148_abnormal_hypersensitivity_rea2.17418424
24MP0002735_abnormal_chemical_nociception2.17397075
25MP0003436_decreased_susceptibility_to2.15518686
26MP0001440_abnormal_grooming_behavior2.14365074
27MP0009780_abnormal_chondrocyte_physiolo2.09474729
28MP0002733_abnormal_thermal_nociception2.06173352
29MP0002067_abnormal_sensory_capabilities1.98003582
30MP0001984_abnormal_olfaction1.96870143
31MP0001970_abnormal_pain_threshold1.96710385
32MP0004510_myositis1.96475543
33MP0005000_abnormal_immune_tolerance1.92608130
34MP0006276_abnormal_autonomic_nervous1.89891010
35MP0002184_abnormal_innervation1.81593660
36MP0005386_behavior/neurological_phenoty1.77519034
37MP0004924_abnormal_behavior1.77519034
38MP0002557_abnormal_social/conspecific_i1.76786379
39MP0008569_lethality_at_weaning1.76648805
40MP0009785_altered_susceptibility_to1.76582114
41MP0000778_abnormal_nervous_system1.74975128
42MP0002909_abnormal_adrenal_gland1.74498820
43MP0005646_abnormal_pituitary_gland1.74296060
44MP0003329_amyloid_beta_deposits1.73639286
45MP0001835_abnormal_antigen_presentation1.73229260
46MP0005167_abnormal_blood-brain_barrier1.72627830
47MP0004811_abnormal_neuron_physiology1.72054431
48MP0004858_abnormal_nervous_system1.70532946
49MP0002419_abnormal_innate_immunity1.65704770
50MP0009764_decreased_sensitivity_to1.65656696
51MP0001529_abnormal_vocalization1.58226071
52MP0008877_abnormal_DNA_methylation1.57533730
53MP0001800_abnormal_humoral_immune1.53279868
54MP0005387_immune_system_phenotype1.52546450
55MP0001790_abnormal_immune_system1.52546450
56MP0003879_abnormal_hair_cell1.51577714
57MP0000955_abnormal_spinal_cord1.50879842
58MP0002452_abnormal_antigen_presenting1.47107667
59MP0002723_abnormal_immune_serum1.46368021
60MP0003787_abnormal_imprinting1.45449086
61MP0001905_abnormal_dopamine_level1.44575936
62MP0002882_abnormal_neuron_morphology1.43727608
63MP0005310_abnormal_salivary_gland1.42740014
64MP0002066_abnormal_motor_capabilities/c1.39986639
65MP0003122_maternal_imprinting1.39734988
66MP0004885_abnormal_endolymph1.39412571
67MP0005058_abnormal_lysosome_morphology1.37440485
68MP0000685_abnormal_immune_system1.36668327
69MP0001188_hyperpigmentation1.35622157
70MP0003195_calcinosis1.32079136
71MP0001533_abnormal_skeleton_physiology1.28954801
72MP0003633_abnormal_nervous_system1.28864184
73MP0005025_abnormal_response_to1.25486221
74MP0001502_abnormal_circadian_rhythm1.25386757
75MP0003300_gastrointestinal_ulcer1.25044821
76MP0005645_abnormal_hypothalamus_physiol1.22835082
77MP0002420_abnormal_adaptive_immunity1.22026460
78MP0001819_abnormal_immune_cell1.22008978
79MP0005551_abnormal_eye_electrophysiolog1.21513628
80MP0004142_abnormal_muscle_tone1.13758438
81MP0000015_abnormal_ear_pigmentation1.09897922
82MP0002152_abnormal_brain_morphology1.09498288
83MP0003631_nervous_system_phenotype1.09239173
84MP0005174_abnormal_tail_pigmentation1.09049365
85MP0008872_abnormal_physiological_respon1.08097199
86MP0000569_abnormal_digit_pigmentation1.07049540
87MP0000343_altered_response_to1.06528600
88MP0000013_abnormal_adipose_tissue1.03877379
89MP0002837_dystrophic_cardiac_calcinosis1.02422615
90MP0002229_neurodegeneration1.02024322
91MP0002998_abnormal_bone_remodeling1.01005850
92MP0010386_abnormal_urinary_bladder1.00817448
93MP0002332_abnormal_exercise_endurance1.00584548
94MP0003183_abnormal_peptide_metabolism0.97449365
95MP0001845_abnormal_inflammatory_respons0.96768163
96MP0002405_respiratory_system_inflammati0.94619051
97MP0000371_diluted_coat_color0.93653216
98MP0005394_taste/olfaction_phenotype0.93191246
99MP0005499_abnormal_olfactory_system0.93191246
100MP0002069_abnormal_eating/drinking_beha0.91499771
101MP0008874_decreased_physiological_sensi0.91169822
102MP0009840_abnormal_foam_cell0.89829816
103MP0002254_reproductive_system_inflammat0.89149325
104MP0003448_altered_tumor_morphology0.87267143
105MP0004145_abnormal_muscle_electrophysio0.87004267
106MP0004742_abnormal_vestibular_system0.86926188
107MP0001177_atelectasis0.86718529
108MP0004947_skin_inflammation0.83930590
109MP0001963_abnormal_hearing_physiology0.82745335
110MP0000751_myopathy0.82534083
111MP0005535_abnormal_body_temperature0.81265300
112MP0004085_abnormal_heartbeat0.80845967
113MP0002752_abnormal_somatic_nervous0.80617817
114MP0000716_abnormal_immune_system0.79542218
115MP0005166_decreased_susceptibility_to0.77940707
116MP0005409_darkened_coat_color0.77246009
117MP0003634_abnormal_glial_cell0.77225098
118MP0003632_abnormal_nervous_system0.75417229
119MP0003646_muscle_fatigue0.75040459
120MP0000631_abnormal_neuroendocrine_gland0.74897805
121MP0004130_abnormal_muscle_cell0.73611349
122MP0003283_abnormal_digestive_organ0.73116916
123MP0001348_abnormal_lacrimal_gland0.72625936
124MP0001485_abnormal_pinna_reflex0.71644074
125MP0008961_abnormal_basal_metabolism0.71176300
126MP0000604_amyloidosis0.70369931
127MP0002876_abnormal_thyroid_physiology0.70253433
128MP0008469_abnormal_protein_level0.69795184
129MP0002638_abnormal_pupillary_reflex0.69365751
130MP0001664_abnormal_digestion0.68588111
131MP0002090_abnormal_vision0.68471426
132MP0001853_heart_inflammation0.67574241
133MP0006072_abnormal_retinal_apoptosis0.65303933
134MP0004484_altered_response_of0.64989802
135MP0004233_abnormal_muscle_weight0.63234663
136MP0003075_altered_response_to0.63195889
137MP0004215_abnormal_myocardial_fiber0.61200526
138MP0005187_abnormal_penis_morphology0.60613080
139MP0001299_abnormal_eye_distance/0.60185864
140MP0000920_abnormal_myelination0.57674854
141MP0001943_abnormal_respiration0.57339841
142MP0003690_abnormal_glial_cell0.57190503
143MP0003861_abnormal_nervous_system0.55493884
144MP0005253_abnormal_eye_physiology0.55103688
145MP0005623_abnormal_meninges_morphology0.55098142
146MP0010769_abnormal_survival0.51629425
147MP0004043_abnormal_pH_regulation0.51554012
148MP0003137_abnormal_impulse_conducting0.51361232
149MP0010770_preweaning_lethality0.50756466

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)8.18894259
2Myokymia (HP:0002411)6.63240799
3Focal seizures (HP:0007359)6.02261896
4Visual hallucinations (HP:0002367)5.29758836
5Atonic seizures (HP:0010819)5.08238283
6Epileptic encephalopathy (HP:0200134)5.07626336
7Abnormality of liposaccharide metabolism (HP:0010968)4.94660359
8Abnormality of glycosphingolipid metabolism (HP:0004343)4.94660359
9Abnormality of glycolipid metabolism (HP:0010969)4.94660359
10Febrile seizures (HP:0002373)4.62465603
11Absence seizures (HP:0002121)4.44397824
12Progressive cerebellar ataxia (HP:0002073)4.33184499
13Dialeptic seizures (HP:0011146)4.07007917
14Hyperventilation (HP:0002883)3.96657697
15Generalized tonic-clonic seizures (HP:0002069)3.94877060
16Broad-based gait (HP:0002136)3.71982761
17Stomatitis (HP:0010280)3.70923386
18Action tremor (HP:0002345)3.65845083
19Retrobulbar optic neuritis (HP:0100654)3.62692858
20Optic neuritis (HP:0100653)3.62692858
21Disinhibition (HP:0000734)3.47028086
22Gaze-evoked nystagmus (HP:0000640)3.40923984
23Poor eye contact (HP:0000817)3.37725502
24Supranuclear gaze palsy (HP:0000605)3.31555148
25Impaired vibration sensation in the lower limbs (HP:0002166)3.29483486
26Increased cerebral lipofuscin (HP:0011813)3.26744782
27Amblyopia (HP:0000646)3.20653044
28Depression (HP:0000716)3.17492094
29Truncal ataxia (HP:0002078)3.16381046
30Orchitis (HP:0100796)3.14107272
31Recurrent bacterial skin infections (HP:0005406)3.13928377
32Ankle clonus (HP:0011448)3.13309382
33Dysdiadochokinesis (HP:0002075)3.11276429
34Anxiety (HP:0000739)3.04088635
35Abnormality of macrophages (HP:0004311)3.03489030
36Abnormal social behavior (HP:0012433)3.00783775
37Impaired social interactions (HP:0000735)3.00783775
38Urinary bladder sphincter dysfunction (HP:0002839)2.99364894
39Dysmetria (HP:0001310)2.93503689
40Dysostosis multiplex (HP:0000943)2.86734279
41Vacuolated lymphocytes (HP:0001922)2.86460951
42Apathy (HP:0000741)2.83953381
43Drooling (HP:0002307)2.79003957
44Excessive salivation (HP:0003781)2.79003957
45Postural instability (HP:0002172)2.78762842
46Impaired smooth pursuit (HP:0007772)2.77227625
47Papilledema (HP:0001085)2.76881172
48Eczematoid dermatitis (HP:0000976)2.74838774
49T lymphocytopenia (HP:0005403)2.74069416
50Abnormal eating behavior (HP:0100738)2.71615796
51Myositis (HP:0100614)2.69235905
52Diminished motivation (HP:0000745)2.68127859
53Genetic anticipation (HP:0003743)2.67906068
54Epileptiform EEG discharges (HP:0011182)2.65544480
55Neuronal loss in central nervous system (HP:0002529)2.65258704
56Limb dystonia (HP:0002451)2.62923564
57Increased neuronal autofluorescent lipopigment (HP:0002074)2.62134491
58Loss of speech (HP:0002371)2.61112035
59Recurrent abscess formation (HP:0002722)2.59125576
60Scanning speech (HP:0002168)2.58646200
61Termporal pattern (HP:0011008)2.58128745
62Insidious onset (HP:0003587)2.58128745
63Cerebral inclusion bodies (HP:0100314)2.56990843
64Pheochromocytoma (HP:0002666)2.55492336
65Urinary urgency (HP:0000012)2.55141059
66Hematochezia (HP:0002573)2.53965917
67Absent speech (HP:0001344)2.52812153
68Progressive inability to walk (HP:0002505)2.50353414
69Global brain atrophy (HP:0002283)2.50221548
70EEG with generalized epileptiform discharges (HP:0011198)2.49941795
71Torticollis (HP:0000473)2.48802122
72Mutism (HP:0002300)2.47881081
73Abnormality of T cell number (HP:0011839)2.47479662
74Agnosia (HP:0010524)2.47034903
75Bradykinesia (HP:0002067)2.46276294
76Abnormality of the lower motor neuron (HP:0002366)2.45823411
77Spastic gait (HP:0002064)2.43513323
78Stereotypic behavior (HP:0000733)2.40057717
79Focal dystonia (HP:0004373)2.39849074
80Hemiparesis (HP:0001269)2.37633127
81Abnormality of ocular smooth pursuit (HP:0000617)2.36656973
82Dysmetric saccades (HP:0000641)2.36376205
83Abnormality of polysaccharide metabolism (HP:0011012)2.36308038
84Abnormality of glycosaminoglycan metabolism (HP:0004371)2.36308038
85Abnormality of mucopolysaccharide metabolism (HP:0011020)2.36308038
86Hypsarrhythmia (HP:0002521)2.36009540
87Neurofibrillary tangles (HP:0002185)2.31422188
88Diplopia (HP:0000651)2.30982355
89Abnormality of binocular vision (HP:0011514)2.30982355
90Impaired vibratory sensation (HP:0002495)2.30204991
91Keratoconjunctivitis (HP:0001096)2.29687303
92Degeneration of the lateral corticospinal tracts (HP:0002314)2.29424739
93Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.29424739
94Inability to walk (HP:0002540)2.27650518
95Memory impairment (HP:0002354)2.26777963
96Mediastinal lymphadenopathy (HP:0100721)2.26735571
97Megalencephaly (HP:0001355)2.24949415
98Autoimmune thrombocytopenia (HP:0001973)2.24936004
99Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.24907648
100Keratoconjunctivitis sicca (HP:0001097)2.24392354
101Abnormality of the corticospinal tract (HP:0002492)2.21993342
102Urinary glycosaminoglycan excretion (HP:0003541)2.21456270
103Mucopolysacchariduria (HP:0008155)2.21456270
104Status epilepticus (HP:0002133)2.19068402
105Generalized myoclonic seizures (HP:0002123)2.17951777
106Neuroendocrine neoplasm (HP:0100634)2.17941920
107Spastic tetraparesis (HP:0001285)2.15909037
108Ocular albinism (HP:0001107)2.13641291
109Craniofacial dystonia (HP:0012179)2.12860434
110Abnormality of the periventricular white matter (HP:0002518)2.12154916
111Fetal akinesia sequence (HP:0001989)2.11594418
112Intention tremor (HP:0002080)2.11550507
113Resting tremor (HP:0002322)2.09993341
114Agitation (HP:0000713)2.07308216
115Pulmonary infiltrates (HP:0002113)2.05971018
116Iris hypopigmentation (HP:0007730)2.05255440
117Elevated erythrocyte sedimentation rate (HP:0003565)2.05230718
118Lower limb muscle weakness (HP:0007340)2.04127764
119Abnormality of the vasculature of the conjunctiva (HP:0008054)2.04100361
120Blue irides (HP:0000635)2.01589127
121Protruding tongue (HP:0010808)1.99919213
122Macroglossia (HP:0000158)1.99885667
123Gait ataxia (HP:0002066)1.99882092
124Delusions (HP:0000746)1.99461501
125Gait imbalance (HP:0002141)1.98864583
126Hemoptysis (HP:0002105)1.98736853
127Hemiplegia (HP:0002301)1.98560212
128Annular pancreas (HP:0001734)1.98437810
129Albinism (HP:0001022)1.95397781
130Abnormality of salivation (HP:0100755)1.93748790
131Incomplete penetrance (HP:0003829)1.92057146
132Polyphagia (HP:0002591)1.89575517
133Ventricular fibrillation (HP:0001663)1.84750125
134Generalized hypopigmentation of hair (HP:0011358)1.83517184
135Central scotoma (HP:0000603)1.81982898
136Retinal dysplasia (HP:0007973)1.81380277
137Episodic fever (HP:0001954)1.80989753
138Specific learning disability (HP:0001328)1.80817203
139Psychosis (HP:0000709)1.80278831
140Dementia (HP:0000726)1.79893020
141Hypoventilation (HP:0002791)1.77405197
142Inappropriate behavior (HP:0000719)1.77002506
143Thickened helices (HP:0000391)1.74324207
144Rigidity (HP:0002063)1.73434249
145Hyperthyroidism (HP:0000836)1.71379140
146Failure to thrive in infancy (HP:0001531)1.69865108
147Neoplasm of the peripheral nervous system (HP:0100007)1.69794475
148Rapidly progressive (HP:0003678)1.69603459
149Lower limb asymmetry (HP:0100559)1.68480434
150Abnormality of saccadic eye movements (HP:0000570)1.67423476
151Amyotrophic lateral sclerosis (HP:0007354)1.66638162
152Congenital primary aphakia (HP:0007707)1.65922799

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA44.59530797
2NTRK34.37132331
3MAP3K93.67471203
4MAP3K43.25396369
5MAP2K72.82663872
6MINK12.67408285
7MARK12.61635962
8DAPK22.60560689
9RIPK42.34754873
10CASK2.28634260
11MAP3K122.23988920
12ACVR1B2.18055696
13PAK62.17599200
14TXK2.17312388
15MAP2K42.03587090
16NTRK12.02955225
17KSR21.99932868
18MAP3K141.95064731
19NTRK21.86038059
20PLK21.79603787
21PRKD31.75215925
22DAPK11.74181068
23GRK71.73238585
24CAMKK11.71624503
25PNCK1.70423924
26KSR11.70332766
27ADRBK21.63547891
28PDK21.62746211
29CDK191.61822134
30TAOK31.59157394
31CDK51.54278536
32GRK51.54110726
33ARAF1.47286459
34IRAK31.39099758
35FRK1.36862697
36MAP4K21.28082998
37PRKCG1.24243560
38TNIK1.24097896
39IRAK41.23209994
40MAP3K21.22106994
41CAMKK21.21835103
42STK381.19091123
43SIK21.18938032
44JAK11.17928806
45IKBKE1.13631342
46MAPK131.13608348
47BLK1.11814212
48IRAK21.10252807
49CAMK2A1.08429571
50FES1.06917123
51TYK21.06382149
52CSK1.05661367
53PRPF4B1.03356516
54BMPR21.01638241
55UHMK11.01566814
56MAP3K131.01470743
57SYK1.00750127
58IKBKB1.00325272
59LATS20.96064288
60OXSR10.95988501
61SGK4940.95896216
62SGK2230.95896216
63TYRO30.92622369
64CDK180.92193322
65MAP3K110.92153182
66IRAK10.90461138
67CDK140.90231682
68CAMK2B0.88534539
69PTK2B0.88483649
70CDK150.88471470
71MATK0.87941894
72MARK30.83292281
73STK110.82889344
74RAF10.82672083
75CAMK10.81756162
76SGK20.81726560
77RET0.81314939
78CDK11A0.76419606
79PAK30.75950867
80CSNK1G20.75817404
81DDR20.75402320
82TAOK10.75084463
83PHKG10.73309496
84PHKG20.73309496
85MAPK120.73164610
86TGFBR20.73042907
87PINK10.72948998
88JAK20.71188407
89SGK10.70723149
90PRKCH0.68574998
91HCK0.67688986
92MOS0.66154431
93SGK30.65867821
94CCNB10.65563905
95DYRK1A0.64588471
96AKT30.62194890
97JAK30.61288550
98PDK10.58657973
99FGR0.57130593
100TBK10.57005455
101SCYL20.56994159
102PDPK10.56225083
103MAPK70.56067798
104BMPR1B0.54465313
105PKN10.54433422
106CAMK2D0.53640948
107CHUK0.53013636
108LYN0.52941425
109LCK0.52710344
110FER0.52580571
111TEC0.52423754
112PRKCE0.52369943
113WNK30.51922285
114MAP2K60.51047986
115NLK0.50421369
116ALK0.50238399
117ZAP700.50156309
118PRKCZ0.50136443
119ITK0.50116235
120MAP3K10.49749047
121CAMK2G0.49636438
122MARK20.49457017
123CAMK1D0.48415360
124BCR0.47730192
125TNK20.46586534
126RPS6KA30.46511539
127LMTK20.46237987
128TRIM280.46086947
129MAP2K10.45610721
130WNK10.44944399
131MAPK100.43601219
132PRKCQ0.43506272
133CAMK1G0.43258848
134NME10.43207109
135NEK60.41950391
136SIK30.41477540
137BRAF0.40770890
138MAP4K10.39291330
139FYN0.39243600
140DAPK30.37941203
141CAMK40.37319911
142MAPKAPK50.36485374
143ROCK20.33822651
144ADRBK10.33377405
145PRKCB0.32806633
146MAP3K60.32779267

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.73049620
2Synaptic vesicle cycle_Homo sapiens_hsa047213.43883000
3Olfactory transduction_Homo sapiens_hsa047403.00713095
4Long-term potentiation_Homo sapiens_hsa047202.78126223
5Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.71935881
6GABAergic synapse_Homo sapiens_hsa047272.69453693
7Circadian entrainment_Homo sapiens_hsa047132.68887470
8Amphetamine addiction_Homo sapiens_hsa050312.62626728
9Glutamatergic synapse_Homo sapiens_hsa047242.54552514
10Morphine addiction_Homo sapiens_hsa050322.52571390
11Dopaminergic synapse_Homo sapiens_hsa047282.31338781
12Salivary secretion_Homo sapiens_hsa049702.18739498
13Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.18671184
14Osteoclast differentiation_Homo sapiens_hsa043802.12662010
15Insulin secretion_Homo sapiens_hsa049112.05955779
16Cholinergic synapse_Homo sapiens_hsa047251.93628318
17NOD-like receptor signaling pathway_Homo sapiens_hsa046211.92071688
18Gastric acid secretion_Homo sapiens_hsa049711.87016136
19Toll-like receptor signaling pathway_Homo sapiens_hsa046201.82972840
20Taste transduction_Homo sapiens_hsa047421.82358149
21Aldosterone synthesis and secretion_Homo sapiens_hsa049251.80015618
22Collecting duct acid secretion_Homo sapiens_hsa049661.77764575
23Renin secretion_Homo sapiens_hsa049241.77022588
24Serotonergic synapse_Homo sapiens_hsa047261.76604423
25Long-term depression_Homo sapiens_hsa047301.73391443
26Cocaine addiction_Homo sapiens_hsa050301.72183979
27Lysosome_Homo sapiens_hsa041421.67395534
28Oxytocin signaling pathway_Homo sapiens_hsa049211.63712257
29Phototransduction_Homo sapiens_hsa047441.62123353
30Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.61796305
31Calcium signaling pathway_Homo sapiens_hsa040201.58741378
32Tuberculosis_Homo sapiens_hsa051521.57730123
33Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.48615761
34Leishmaniasis_Homo sapiens_hsa051401.44738293
35NF-kappa B signaling pathway_Homo sapiens_hsa040641.43706522
36GnRH signaling pathway_Homo sapiens_hsa049121.43455584
37Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.40363684
38TNF signaling pathway_Homo sapiens_hsa046681.38159899
39Gap junction_Homo sapiens_hsa045401.36723536
40T cell receptor signaling pathway_Homo sapiens_hsa046601.30603775
41Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.30193912
42Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.27749440
43Legionellosis_Homo sapiens_hsa051341.27202679
44cAMP signaling pathway_Homo sapiens_hsa040241.24718487
45Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.22837067
46B cell receptor signaling pathway_Homo sapiens_hsa046621.22150909
47RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.21746784
48Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.19593956
49Vibrio cholerae infection_Homo sapiens_hsa051101.17463022
50Phosphatidylinositol signaling system_Homo sapiens_hsa040701.17307081
51Estrogen signaling pathway_Homo sapiens_hsa049151.16290981
52Glioma_Homo sapiens_hsa052141.13188405
53Malaria_Homo sapiens_hsa051441.12289754
54Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.11044733
55Pertussis_Homo sapiens_hsa051331.08850457
56Type II diabetes mellitus_Homo sapiens_hsa049301.06701350
57Melanogenesis_Homo sapiens_hsa049161.05965132
58Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.05911960
59cGMP-PKG signaling pathway_Homo sapiens_hsa040221.05265929
60Phagosome_Homo sapiens_hsa041451.02968532
61Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.02573360
62Axon guidance_Homo sapiens_hsa043601.01902788
63Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.01824377
64Allograft rejection_Homo sapiens_hsa053301.00869421
65Glycosaminoglycan degradation_Homo sapiens_hsa005311.00524782
66ErbB signaling pathway_Homo sapiens_hsa040120.99627089
67Graft-versus-host disease_Homo sapiens_hsa053320.99184802
68Cardiac muscle contraction_Homo sapiens_hsa042600.98767419
69Intestinal immune network for IgA production_Homo sapiens_hsa046720.94934250
70Salmonella infection_Homo sapiens_hsa051320.93590308
71Vascular smooth muscle contraction_Homo sapiens_hsa042700.93482073
72Oocyte meiosis_Homo sapiens_hsa041140.93375657
73Staphylococcus aureus infection_Homo sapiens_hsa051500.89302667
74Other glycan degradation_Homo sapiens_hsa005110.87415591
75Asthma_Homo sapiens_hsa053100.87345874
76Dorso-ventral axis formation_Homo sapiens_hsa043200.85992552
77Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.85150582
78Nitrogen metabolism_Homo sapiens_hsa009100.82804413
79Pancreatic secretion_Homo sapiens_hsa049720.81798115
80Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.80525710
81Toxoplasmosis_Homo sapiens_hsa051450.79710571
82Thyroid hormone synthesis_Homo sapiens_hsa049180.78643318
83Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.75061613
84Phospholipase D signaling pathway_Homo sapiens_hsa040720.71829840
85Measles_Homo sapiens_hsa051620.71812227
86Jak-STAT signaling pathway_Homo sapiens_hsa046300.71717379
87Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.69953460
88Prolactin signaling pathway_Homo sapiens_hsa049170.68595482
89Influenza A_Homo sapiens_hsa051640.68023981
90Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.66664221
91MAPK signaling pathway_Homo sapiens_hsa040100.66259306
92Glucagon signaling pathway_Homo sapiens_hsa049220.65406451
93AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.64780532
94Choline metabolism in cancer_Homo sapiens_hsa052310.64256343
95Alzheimers disease_Homo sapiens_hsa050100.63396099
96Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.63201438
97Dilated cardiomyopathy_Homo sapiens_hsa054140.62745483
98Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.62700249
99Hematopoietic cell lineage_Homo sapiens_hsa046400.61802846
100Autoimmune thyroid disease_Homo sapiens_hsa053200.61308804
101Primary immunodeficiency_Homo sapiens_hsa053400.60501096
102Alcoholism_Homo sapiens_hsa050340.58498071
103VEGF signaling pathway_Homo sapiens_hsa043700.58051663
104Hepatitis B_Homo sapiens_hsa051610.58021913
105Neurotrophin signaling pathway_Homo sapiens_hsa047220.57480703
106Ras signaling pathway_Homo sapiens_hsa040140.56076671
107Ether lipid metabolism_Homo sapiens_hsa005650.55307058
108Rap1 signaling pathway_Homo sapiens_hsa040150.53148272
109Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.52407294
110Type I diabetes mellitus_Homo sapiens_hsa049400.52314935
111Inositol phosphate metabolism_Homo sapiens_hsa005620.51759954
112Oxidative phosphorylation_Homo sapiens_hsa001900.50058238
113Carbohydrate digestion and absorption_Homo sapiens_hsa049730.49890034
114Sphingolipid metabolism_Homo sapiens_hsa006000.49723677
115Sphingolipid signaling pathway_Homo sapiens_hsa040710.48226431
116FoxO signaling pathway_Homo sapiens_hsa040680.47320235
117mTOR signaling pathway_Homo sapiens_hsa041500.47072507
118Circadian rhythm_Homo sapiens_hsa047100.47037320
119Thyroid hormone signaling pathway_Homo sapiens_hsa049190.46376778
120Platelet activation_Homo sapiens_hsa046110.45690776
121African trypanosomiasis_Homo sapiens_hsa051430.45095595
122Wnt signaling pathway_Homo sapiens_hsa043100.42852560
123Prion diseases_Homo sapiens_hsa050200.41897774
124Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.41544025
125Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.40258919
126Endocytosis_Homo sapiens_hsa041440.39296265
127Parkinsons disease_Homo sapiens_hsa050120.38981474
128Non-small cell lung cancer_Homo sapiens_hsa052230.38523884
129Bile secretion_Homo sapiens_hsa049760.37999342
130Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.37256673
131Renal cell carcinoma_Homo sapiens_hsa052110.37139079
132Insulin signaling pathway_Homo sapiens_hsa049100.36799600
133Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.35810009
134Longevity regulating pathway - mammal_Homo sapiens_hsa042110.35675145
135Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.33792068
136Endometrial cancer_Homo sapiens_hsa052130.33460432
137Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.33240803
138Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.32686722
139Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.30144123
140SNARE interactions in vesicular transport_Homo sapiens_hsa041300.29224987
141Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.28691679
142Ovarian steroidogenesis_Homo sapiens_hsa049130.27977916
143Rheumatoid arthritis_Homo sapiens_hsa053230.22753392
144Chemokine signaling pathway_Homo sapiens_hsa040620.22556299

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