SH3PXD2A

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1protein heterotrimerization (GO:0070208)5.75167351
2collagen fibril organization (GO:0030199)4.87554785
3regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)4.23941217
4low-density lipoprotein particle clearance (GO:0034383)4.16803274
5plasma membrane repair (GO:0001778)4.05893193
6positive regulation of fatty acid beta-oxidation (GO:0032000)4.01777527
7insulin-like growth factor receptor signaling pathway (GO:0048009)3.96446943
8desmosome organization (GO:0002934)3.84313134
9cell migration involved in heart development (GO:0060973)3.83437813
10bone trabecula formation (GO:0060346)3.82930566
11endodermal cell differentiation (GO:0035987)3.82480160
12chondrocyte proliferation (GO:0035988)3.81829448
13negative regulation of fatty acid transport (GO:2000192)3.75912775
14white fat cell differentiation (GO:0050872)3.69869871
15neuron projection extension involved in neuron projection guidance (GO:1902284)3.67768647
16axon extension involved in axon guidance (GO:0048846)3.67768647
17skin morphogenesis (GO:0043589)3.60266782
18hemidesmosome assembly (GO:0031581)3.54226033
19positive regulation of fatty acid oxidation (GO:0046321)3.53648236
20collagen metabolic process (GO:0032963)3.48304765
21collagen catabolic process (GO:0030574)3.43699071
22regulation of fatty acid beta-oxidation (GO:0031998)3.41204226
23regulation of sequestering of triglyceride (GO:0010889)3.37958662
24extracellular matrix assembly (GO:0085029)3.37129548
25vascular endothelial growth factor signaling pathway (GO:0038084)3.35689085
26multicellular organismal macromolecule metabolic process (GO:0044259)3.35434289
27basement membrane organization (GO:0071711)3.35109205
28cellular response to vitamin (GO:0071295)3.34413254
29sequestering of extracellular ligand from receptor (GO:0035581)3.34372900
30positive regulation of glycogen biosynthetic process (GO:0045725)3.33523790
31regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.32979289
32retina vasculature morphogenesis in camera-type eye (GO:0061299)3.29631516
33apoptotic cell clearance (GO:0043277)3.25013360
34multicellular organismal metabolic process (GO:0044236)3.23640003
35multicellular organismal catabolic process (GO:0044243)3.17774564
36mesenchymal-epithelial cell signaling (GO:0060638)3.17605400
37planar cell polarity pathway involved in neural tube closure (GO:0090179)3.14011938
38cell-substrate junction assembly (GO:0007044)3.11974677
39extracellular fibril organization (GO:0043206)3.08077990
40kidney mesenchyme development (GO:0072074)3.06747257
41cell adhesion mediated by integrin (GO:0033627)3.06606481
42endocardial cushion development (GO:0003197)3.06144815
43regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 3.05115222
44regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.04270909
45extracellular matrix disassembly (GO:0022617)3.03305177
46hippo signaling (GO:0035329)3.02857467
47positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.99825189
48cell-substrate adherens junction assembly (GO:0007045)2.98911939
49focal adhesion assembly (GO:0048041)2.98911939
50cartilage development involved in endochondral bone morphogenesis (GO:0060351)2.98477869
51atrioventricular valve morphogenesis (GO:0003181)2.92750609
52regulation of fatty acid oxidation (GO:0046320)2.92567303
53negative regulation of chondrocyte differentiation (GO:0032331)2.92167996
54growth hormone receptor signaling pathway (GO:0060396)2.91919197
55cell migration involved in sprouting angiogenesis (GO:0002042)2.91807683
56negative regulation of cartilage development (GO:0061037)2.84899280
57positive regulation of endothelial cell apoptotic process (GO:2000353)2.84145756
58hypotonic response (GO:0006971)2.83476733
59craniofacial suture morphogenesis (GO:0097094)2.82519220
60positive regulation of glycogen metabolic process (GO:0070875)2.81941130
61negative regulation of smooth muscle cell migration (GO:0014912)2.81519648
62regulation of glucose import in response to insulin stimulus (GO:2001273)2.80817663
63type B pancreatic cell proliferation (GO:0044342)2.80051348
64Golgi transport vesicle coating (GO:0048200)2.76667851
65COPI coating of Golgi vesicle (GO:0048205)2.76667851
66positive regulation of histone deacetylation (GO:0031065)2.74409278
67synaptic vesicle docking involved in exocytosis (GO:0016081)2.72929894
68renal filtration (GO:0097205)2.72434126
69adhesion of symbiont to host cell (GO:0044650)2.71955073
70virion attachment to host cell (GO:0019062)2.71955073
71stress fiber assembly (GO:0043149)2.70456975
72glomerular filtration (GO:0003094)2.70289350
73embryonic retina morphogenesis in camera-type eye (GO:0060059)2.69810207
74positive regulation of cellular response to insulin stimulus (GO:1900078)2.69448732
75fibril organization (GO:0097435)2.69296803
76brown fat cell differentiation (GO:0050873)2.69141681
77outer ear morphogenesis (GO:0042473)2.68414838
78epithelial cell-cell adhesion (GO:0090136)2.68186527
79protein retention in ER lumen (GO:0006621)2.66698000
80regulation of tight junction assembly (GO:2000810)2.66300205
81carnitine shuttle (GO:0006853)2.65557895
82fatty acid transmembrane transport (GO:1902001)2.65467678
83adherens junction assembly (GO:0034333)2.64440927
84triglyceride catabolic process (GO:0019433)2.63503941
85regulation of cholesterol storage (GO:0010885)2.59286717
86cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.58790099
87protein localization to endosome (GO:0036010)2.58309041
88semaphorin-plexin signaling pathway (GO:0071526)2.58024664
89negative regulation of catenin import into nucleus (GO:0035414)2.57828282
90protein localization to cell surface (GO:0034394)2.57050957
91chondrocyte development (GO:0002063)2.56830584
92regulation of extracellular matrix disassembly (GO:0010715)2.56470829
93cellular response to vitamin D (GO:0071305)2.56078177
94adhesion of symbiont to host (GO:0044406)2.55685544
95maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.54070827
96negative regulation of macrophage derived foam cell differentiation (GO:0010745)2.53934258
97positive regulation of p38MAPK cascade (GO:1900745)2.53291251
98endothelial cell chemotaxis (GO:0035767)2.52902932
99valine metabolic process (GO:0006573)2.52183151
100positive regulation of mesenchymal cell proliferation (GO:0002053)2.52171212
101lipid particle organization (GO:0034389)2.51988013
102smooth muscle tissue development (GO:0048745)2.50350025
103glomerular basement membrane development (GO:0032836)2.50341864
104cellular response to growth hormone stimulus (GO:0071378)2.50152283
105cardiac myofibril assembly (GO:0055003)2.49915755
106extracellular matrix organization (GO:0030198)2.49424056
107positive regulation of blood vessel endothelial cell migration (GO:0043536)2.48675419
108Wnt signaling pathway, planar cell polarity pathway (GO:0060071)2.48381706
109negative regulation of cell size (GO:0045792)2.48336257
110extracellular structure organization (GO:0043062)2.48306786
111venous blood vessel morphogenesis (GO:0048845)2.48296728
112positive regulation of glucose import (GO:0046326)2.48091056
113substrate-dependent cell migration (GO:0006929)2.48012627
114regulation of p38MAPK cascade (GO:1900744)2.46830934
115acylglycerol catabolic process (GO:0046464)2.46697661
116neutral lipid catabolic process (GO:0046461)2.46697661
117endocytic recycling (GO:0032456)2.46585243
118vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.46121265
119regulation of axon extension involved in axon guidance (GO:0048841)2.45807966
120protein carboxylation (GO:0018214)2.44143885
121peptidyl-glutamic acid carboxylation (GO:0017187)2.44143885
122heart morphogenesis (GO:0003007)2.42176254
123cytoskeletal anchoring at plasma membrane (GO:0007016)2.41975330
124cardiac muscle cell proliferation (GO:0060038)2.41008525
125protein hydroxylation (GO:0018126)2.40944455
126epoxygenase P450 pathway (GO:0019373)2.40677519
127dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.40305888
128endothelial cell morphogenesis (GO:0001886)2.39283232
129blood vessel endothelial cell migration (GO:0043534)2.39035882
130trabecula formation (GO:0060343)2.39015241
131activation of signaling protein activity involved in unfolded protein response (GO:0006987)2.38862032
132regulation of establishment of planar polarity (GO:0090175)2.38684637
133barbed-end actin filament capping (GO:0051016)2.38654521
134gastrulation with mouth forming second (GO:0001702)2.38363439
135metanephric mesenchyme development (GO:0072075)2.37171046
136polarized epithelial cell differentiation (GO:0030859)2.37155811
137pericardium development (GO:0060039)2.36336323
138paraxial mesoderm development (GO:0048339)2.36006803
139regulation of plasminogen activation (GO:0010755)2.35781326
140branching involved in salivary gland morphogenesis (GO:0060445)2.35517387
141substrate adhesion-dependent cell spreading (GO:0034446)2.32925823
142surfactant homeostasis (GO:0043129)2.31335415
143regulation of early endosome to late endosome transport (GO:2000641)2.30738531
144actin filament depolymerization (GO:0030042)2.26993187
145peptide cross-linking (GO:0018149)2.26853886
146peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)2.24046420
147positive regulation of osteoblast proliferation (GO:0033690)2.22278482
148cochlea morphogenesis (GO:0090103)2.21425100
149positive regulation of fibroblast migration (GO:0010763)2.20742402
150muscle cell migration (GO:0014812)2.18282206
151wound healing, spreading of epidermal cells (GO:0035313)2.18086452
152keratinocyte proliferation (GO:0043616)2.17896521
153protein targeting to plasma membrane (GO:0072661)2.17636964
154neurological system process involved in regulation of systemic arterial blood pressure (GO:0001976)2.16800233
155negative regulation of axon extension involved in axon guidance (GO:0048843)2.14883210

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human5.33816567
2PPARG_19300518_ChIP-PET_3T3-L1_Mouse5.00077073
3TRIM28_21343339_ChIP-Seq_HEK293_Human3.96995220
4RARG_19884340_ChIP-ChIP_MEFs_Mouse3.32738938
5CLOCK_20551151_ChIP-Seq_293T_Human3.23919564
6NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.94095549
7* TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.63489147
8* ESR1_22446102_ChIP-Seq_UTERUS_Mouse2.33769296
9* TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human2.28023342
10RUNX2_24764292_ChIP-Seq_MC3T3_Mouse2.12617109
11PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.06192298
12THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.02195097
13STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.00163315
14EP300_21415370_ChIP-Seq_HL-1_Mouse1.94946089
15* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.94394124
16CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.92134630
17* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.87902042
18ESR2_21235772_ChIP-Seq_MCF-7_Human1.75621856
19* CJUN_26792858_Chip-Seq_BT549_Human1.71988856
20CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.70655246
21* NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.69072887
22PPAR_26484153_Chip-Seq_NCI-H1993_Human1.67213230
23SOX9_24532713_ChIP-Seq_HFSC_Mouse1.67198561
24WT1_19549856_ChIP-ChIP_CCG9911_Human1.64022594
25HIF1A_21447827_ChIP-Seq_MCF-7_Human1.63641471
26EED_16625203_ChIP-ChIP_MESCs_Mouse1.62519893
27STAT6_21828071_ChIP-Seq_BEAS2B_Human1.61180223
28TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.60980388
29* TBX20_22328084_ChIP-Seq_HEART_Mouse1.60151287
30* TBX20_22080862_ChIP-Seq_HEART_Mouse1.60151287
31* LXR_22158963_ChIP-Seq_LIVER_Mouse1.60076831
32P300_27058665_Chip-Seq_ZR-75-30cells_Human1.59851317
33ESR1_21235772_ChIP-Seq_MCF-7_Human1.57058197
34SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.54828574
35ELK3_25401928_ChIP-Seq_HUVEC_Human1.54667116
36SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.54208451
37* BRD4_25478319_ChIP-Seq_HGPS_Human1.54064466
38ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.52896317
39ZNF263_19887448_ChIP-Seq_K562_Human1.52244518
40FOXO3_23340844_ChIP-Seq_DLD1_Human1.51781223
41JARID2_20075857_ChIP-Seq_MESCs_Mouse1.51097921
42ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.49820283
43* RXR_22158963_ChIP-Seq_LIVER_Mouse1.48642972
44* DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.48199707
45KDM2B_26808549_Chip-Seq_SUP-B15_Human1.47848000
46MTF2_20144788_ChIP-Seq_MESCs_Mouse1.47127864
47SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.46918835
48* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.46206707
49ERG_21242973_ChIP-ChIP_JURKAT_Human1.43464472
50ESR1_20079471_ChIP-ChIP_T-47D_Human1.42715884
51ZNF217_24962896_ChIP-Seq_MCF-7_Human1.41989860
52MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.41760339
53KDM2B_26808549_Chip-Seq_K562_Human1.40438251
54SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.38866476
55EGR1_19374776_ChIP-ChIP_THP-1_Human1.38852895
56SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.38347892
57* DROSHA_22980978_ChIP-Seq_HELA_Human1.38279739
58TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.35856309
59TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.35209440
60SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.34890387
61SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.34095419
62NRF2_20460467_ChIP-Seq_MEFs_Mouse1.32504732
63NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.32504732
64PPARA_22158963_ChIP-Seq_LIVER_Mouse1.31008418
65* ISL1_27105846_Chip-Seq_CPCs_Mouse1.30598079
66RNF2_27304074_Chip-Seq_ESCs_Mouse1.28810979
67CDX2_19796622_ChIP-Seq_MESCs_Mouse1.28634071
68FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human1.27439324
69PPARG_20176806_ChIP-Seq_3T3-L1_Mouse1.26247484
70KDM2B_26808549_Chip-Seq_DND41_Human1.26076594
71* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.24249557
72RACK7_27058665_Chip-Seq_MCF-7_Human1.23076386
73BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.21375742
74* SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.20105970
75* SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.20105970
76ATF3_27146783_Chip-Seq_COLON_Human1.19089238
77* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.18992475
78* SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.18695671
79NFIB_24661679_ChIP-Seq_LUNG_Mouse1.18390305
80* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.16408194
81EZH2_27304074_Chip-Seq_ESCs_Mouse1.15660718
82ZFP281_27345836_Chip-Seq_ESCs_Mouse1.15444515
83* RNF2_18974828_ChIP-Seq_MESCs_Mouse1.14990159
84* EZH2_18974828_ChIP-Seq_MESCs_Mouse1.14990159
85* UBF1/2_26484160_Chip-Seq_HMECs_Human1.14772208
86GATA2_21666600_ChIP-Seq_HMVEC_Human1.14362736
87EZH2_27294783_Chip-Seq_ESCs_Mouse1.12084806
88TP53_20018659_ChIP-ChIP_R1E_Mouse1.10618805
89KDM2B_26808549_Chip-Seq_JURKAT_Human1.10078257
90* JARID2_20064375_ChIP-Seq_MESCs_Mouse1.10060423
91* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.09341687
92CTCF_27219007_Chip-Seq_Bcells_Human1.08751321
93SUZ12_27294783_Chip-Seq_ESCs_Mouse1.07501797
94SMAD_19615063_ChIP-ChIP_OVARY_Human1.07185915
95* FOXA2_19822575_ChIP-Seq_HepG2_Human1.06330788
96ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.06195554
97AHR_22903824_ChIP-Seq_MCF-7_Human1.05824031
98KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.05782755
99LXR_22292898_ChIP-Seq_THP-1_Human1.04375106
100* UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.03596150
101TP53_16413492_ChIP-PET_HCT116_Human1.03321174
102DNAJC2_21179169_ChIP-ChIP_NT2_Human1.02794295
103* SMC3_22415368_ChIP-Seq_MEFs_Mouse1.02570684
104ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.02553304
105CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.01860661
106RUNX1_27514584_Chip-Seq_MCF-7_Human1.01151556
107* SMC1_22415368_ChIP-Seq_MEFs_Mouse1.01029366
108TET1_21490601_ChIP-Seq_MESCs_Mouse1.00563222
109PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.00336104
110ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.00216152
111HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse0.99109203
112* JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.98350791
113PHC1_16625203_ChIP-ChIP_MESCs_Mouse0.97311059
114FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.96081587
115EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.95713976
116TP53_23651856_ChIP-Seq_MEFs_Mouse0.95566991
117* PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.95555053
118ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.94811994
119* CTNNB1_20460455_ChIP-Seq_HCT116_Human0.94303186
120P63_26484246_Chip-Seq_KERATINOCYTES_Human0.94242310
121TCF7_22412390_ChIP-Seq_EML_Mouse0.93871702
122SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.93598468
123TP53_22127205_ChIP-Seq_IMR90_Human0.93592795
124SALL4_18804426_ChIP-ChIP_XEN_Mouse0.93472051
125* JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.92960597
126TP53_18474530_ChIP-ChIP_U2OS_Human0.92462285
127CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.92395861

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen6.73886271
2MP0005275_abnormal_skin_tensile4.79667544
3MP0003705_abnormal_hypodermis_morpholog4.16771841
4MP0005503_abnormal_tendon_morphology3.40665098
5MP0004272_abnormal_basement_membrane3.11962561
6MP0005670_abnormal_white_adipose2.64066433
7MP0003279_aneurysm2.54323092
8MP0005409_darkened_coat_color2.51627018
9MP0004185_abnormal_adipocyte_glucose2.42045472
10MP0000013_abnormal_adipose_tissue2.24801521
11MP0005666_abnormal_adipose_tissue2.23893557
12MP0002837_dystrophic_cardiac_calcinosis2.22912751
13MP0005623_abnormal_meninges_morphology2.20002657
14MP0003566_abnormal_cell_adhesion2.07660936
15MP0002060_abnormal_skin_morphology2.06079392
16MP0004130_abnormal_muscle_cell2.02550658
17MP0005375_adipose_tissue_phenotype1.97323148
18MP0000003_abnormal_adipose_tissue1.92108409
19MP0002877_abnormal_melanocyte_morpholog1.91804638
20MP0001958_emphysema1.90378546
21MP0000751_myopathy1.81720082
22MP0003045_fibrosis1.80933103
23MP0010352_gastrointestinal_tract_polyps1.66310966
24MP0002896_abnormal_bone_mineralization1.63340602
25MP0000733_abnormal_muscle_development1.63188716
26MP0002108_abnormal_muscle_morphology1.59206930
27MP0005508_abnormal_skeleton_morphology1.58756538
28MP0005076_abnormal_cell_differentiation1.58740911
29MP0005257_abnormal_intraocular_pressure1.58611961
30MP0003283_abnormal_digestive_organ1.56307800
31MP0009384_cardiac_valve_regurgitation1.55368244
32MP0006054_spinal_hemorrhage1.52986115
33MP0005171_absent_coat_pigmentation1.47277853
34MP0009780_abnormal_chondrocyte_physiolo1.46438501
35MP0010030_abnormal_orbit_morphology1.46332435
36MP0001299_abnormal_eye_distance/1.45199771
37MP0004858_abnormal_nervous_system1.43950764
38MP0001542_abnormal_bone_strength1.37724821
39MP0003091_abnormal_cell_migration1.34898312
40MP0000750_abnormal_muscle_regeneration1.33529318
41MP0005023_abnormal_wound_healing1.32984688
42MP0003385_abnormal_body_wall1.32797880
43MP0004087_abnormal_muscle_fiber1.29579316
44MP0003950_abnormal_plasma_membrane1.27892283
45MP0002168_other_aberrant_phenotype1.27018498
46MP0009250_abnormal_appendicular_skeleto1.25675719
47MP0009053_abnormal_anal_canal1.21746553
48MP0000428_abnormal_craniofacial_morphol1.19674495
49MP0004084_abnormal_cardiac_muscle1.18841903
50MP0000467_abnormal_esophagus_morphology1.18757975
51MP0002295_abnormal_pulmonary_circulatio1.17971167
52MP0001243_abnormal_dermal_layer1.15981547
53MP0010368_abnormal_lymphatic_system1.11424617
54MP0002971_abnormal_brown_adipose1.10789334
55MP0006138_congestive_heart_failure1.08648069
56MP0003453_abnormal_keratinocyte_physiol1.08379608
57MP0000767_abnormal_smooth_muscle1.07983999
58MP0000759_abnormal_skeletal_muscle1.06618475
59MP0010234_abnormal_vibrissa_follicle1.06488281
60MP0003942_abnormal_urinary_system1.04334029
61MP0002089_abnormal_postnatal_growth/wei1.01897366
62MP0001849_ear_inflammation1.01146740
63MP0003300_gastrointestinal_ulcer0.99614188
64MP0000534_abnormal_ureter_morphology0.99459410
65MP0010630_abnormal_cardiac_muscle0.99248848
66MP0000163_abnormal_cartilage_morphology0.97395513
67MP0002115_abnormal_skeleton_extremities0.96074645
68MP0003115_abnormal_respiratory_system0.96060401
69MP0009115_abnormal_fat_cell0.94881409
70MP0005595_abnormal_vascular_smooth0.93368840
71MP0000749_muscle_degeneration0.93028159
72MP0002254_reproductive_system_inflammat0.93016793
73MP0002234_abnormal_pharynx_morphology0.91660314
74MP0002796_impaired_skin_barrier0.89777893
75MP0005330_cardiomyopathy0.89508114
76MP0008775_abnormal_heart_ventricle0.89010968
77MP0003935_abnormal_craniofacial_develop0.88364671
78MP0001348_abnormal_lacrimal_gland0.86016013
79MP0002932_abnormal_joint_morphology0.84177739
80MP0001879_abnormal_lymphatic_vessel0.82841384
81MP0000579_abnormal_nail_morphology0.82834993
82MP0000462_abnormal_digestive_system0.81764237
83MP0010771_integument_phenotype0.81723114
84MP0001661_extended_life_span0.81388773
85MP0005334_abnormal_fat_pad0.80838880
86MP0005248_abnormal_Harderian_gland0.79888235
87MP0004134_abnormal_chest_morphology0.79647093
88MP0000537_abnormal_urethra_morphology0.79551139
89MP0005369_muscle_phenotype0.78940642
90MP0003941_abnormal_skin_development0.78389452
91MP0000747_muscle_weakness0.78184749
92MP0005620_abnormal_muscle_contractility0.78167940
93MP0005385_cardiovascular_system_phenoty0.78065285
94MP0001544_abnormal_cardiovascular_syste0.78065285
95MP0004233_abnormal_muscle_weight0.77882761
96MP0002269_muscular_atrophy0.77764059
97MP0003329_amyloid_beta_deposits0.77268435
98MP0003252_abnormal_bile_duct0.76926343
99MP0002282_abnormal_trachea_morphology0.76305723
100MP0002128_abnormal_blood_circulation0.76124316
101MP0003755_abnormal_palate_morphology0.75997934
102MP0004036_abnormal_muscle_relaxation0.74758785
103MP0002970_abnormal_white_adipose0.74596328
104MP0002249_abnormal_larynx_morphology0.74455565
105MP0005390_skeleton_phenotype0.73654557
106MP0000432_abnormal_head_morphology0.72610478
107MP0005388_respiratory_system_phenotype0.72286313
108MP0002133_abnormal_respiratory_system0.72286313
109MP0000762_abnormal_tongue_morphology0.72278148
110MP0002972_abnormal_cardiac_muscle0.72000003
111MP0002998_abnormal_bone_remodeling0.71918251
112MP0002925_abnormal_cardiovascular_devel0.71274028
113MP0001614_abnormal_blood_vessel0.70585116
114MP0010386_abnormal_urinary_bladder0.69696540
115MP0003828_pulmonary_edema0.69638180
116MP0003959_abnormal_lean_body0.69628171
117MP0002113_abnormal_skeleton_development0.69323897
118MP0001915_intracranial_hemorrhage0.67170959
119MP0005058_abnormal_lysosome_morphology0.66465582
120MP0001216_abnormal_epidermal_layer0.65110956
121MP0005501_abnormal_skin_physiology0.64414176
122MP0004859_abnormal_synaptic_plasticity0.63522816
123MP0002933_joint_inflammation0.63467083
124MP0009840_abnormal_foam_cell0.61404127
125MP0005164_abnormal_response_to0.61043380
126MP0000566_synostosis0.59592055

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)6.39646329
2Premature rupture of membranes (HP:0001788)6.03041781
3Ankle contracture (HP:0006466)4.97367299
4Shallow orbits (HP:0000586)4.43336808
5Atrophic scars (HP:0001075)4.38135983
6Broad metatarsal (HP:0001783)4.34655791
7Type 1 muscle fiber predominance (HP:0003803)4.33751793
8Cerebral aneurysm (HP:0004944)4.21571781
9Aortic dissection (HP:0002647)3.99253759
10Increased connective tissue (HP:0009025)3.81994304
11Follicular hyperkeratosis (HP:0007502)3.69801060
12Fragile skin (HP:0001030)3.61986609
13Peritonitis (HP:0002586)3.58026342
14Bladder diverticulum (HP:0000015)3.41537036
15Mitral valve prolapse (HP:0001634)3.35613893
16Arterial tortuosity (HP:0005116)3.35156737
17Spinal rigidity (HP:0003306)3.31336540
18Soft skin (HP:0000977)3.30686821
19Cervical subluxation (HP:0003308)3.18603478
20Dilatation of the ascending aorta (HP:0005111)3.17687310
21Mildly elevated creatine phosphokinase (HP:0008180)3.13287724
22Increased variability in muscle fiber diameter (HP:0003557)3.10184963
23Aortic aneurysm (HP:0004942)3.03933125
24Slender build (HP:0001533)2.99467679
25Genu recurvatum (HP:0002816)2.86823506
26Blue sclerae (HP:0000592)2.69442860
27Abnormality of skeletal muscle fiber size (HP:0012084)2.69166763
28Aneurysm (HP:0002617)2.60139578
29Neonatal short-limb short stature (HP:0008921)2.57897409
30Bowel diverticulosis (HP:0005222)2.55537832
31Abnormality of dentin (HP:0010299)2.48529253
32Wrist flexion contracture (HP:0001239)2.43159128
33Hyperextensible skin (HP:0000974)2.42019757
34Natal tooth (HP:0000695)2.41438198
35Obstructive sleep apnea (HP:0002870)2.41132551
36Short 4th metacarpal (HP:0010044)2.39629651
37Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.39629651
38Hyporeflexia of lower limbs (HP:0002600)2.39238941
39Wormian bones (HP:0002645)2.38968521
40Buphthalmos (HP:0000557)2.30974262
41Difficulty running (HP:0009046)2.30621555
42Deviation of the hallux (HP:0010051)2.29693562
43Right ventricular cardiomyopathy (HP:0011663)2.25906592
44Turricephaly (HP:0000262)2.24215987
45Infantile muscular hypotonia (HP:0008947)2.23706316
46Mitral regurgitation (HP:0001653)2.23464466
47Spondylolisthesis (HP:0003302)2.23381428
48Abnormality of the 4th metacarpal (HP:0010012)2.22872098
49Muscle fiber splitting (HP:0003555)2.21016491
50Wide anterior fontanel (HP:0000260)2.18441142
51Mild short stature (HP:0003502)2.18051572
52Hallux valgus (HP:0001822)2.16965840
53Acanthosis nigricans (HP:0000956)2.14063240
54Scapular winging (HP:0003691)2.13698344
55Elbow flexion contracture (HP:0002987)2.13447055
56Ectopia lentis (HP:0001083)2.12329691
57Ulnar bowing (HP:0003031)2.12112731
58Aortic regurgitation (HP:0001659)2.11973949
59Osteolytic defects of the hand bones (HP:0009699)2.11880841
60Osteolytic defects of the phalanges of the hand (HP:0009771)2.11880841
61Hypoplastic ischia (HP:0003175)2.10280063
62Enlarged penis (HP:0000040)2.09945509
63Joint laxity (HP:0001388)2.09534767
64Striae distensae (HP:0001065)2.08392709
65Overgrowth (HP:0001548)2.08330627
66Lymphangioma (HP:0100764)2.03636639
67Camptodactyly of toe (HP:0001836)2.02287916
68Advanced eruption of teeth (HP:0006288)2.01497465
69Venous abnormality (HP:0002624)2.01203572
70Mitral stenosis (HP:0001718)1.99665270
71Bell-shaped thorax (HP:0001591)1.97879633
72Ulnar deviation of the wrist (HP:0003049)1.97673128
73Difficulty climbing stairs (HP:0003551)1.95998428
74Joint stiffness (HP:0001387)1.95787386
75Thin bony cortex (HP:0002753)1.94201800
76Mesomelia (HP:0003027)1.93965666
77Biconcave vertebral bodies (HP:0004586)1.93784580
78Round ear (HP:0100830)1.93771747
79Alopecia of scalp (HP:0002293)1.90964192
80Asymmetry of the thorax (HP:0001555)1.90094367
81Limited hip movement (HP:0008800)1.90011730
82Abnormality of the ischium (HP:0003174)1.89894493
83Tibial bowing (HP:0002982)1.87827680
84Vertebral compression fractures (HP:0002953)1.85891339
85Hypoplasia of the iris (HP:0007676)1.85788266
86Abnormal delivery (HP:0001787)1.85388843
87Knee flexion contracture (HP:0006380)1.82865032
88Congenital glaucoma (HP:0001087)1.81865411
89Calcaneovalgus deformity (HP:0001848)1.81561752
90Exostoses (HP:0100777)1.81368651
91Long toe (HP:0010511)1.81151568
92Coronal craniosynostosis (HP:0004440)1.80852337
93Upper limb amyotrophy (HP:0009129)1.79761867
94Distal upper limb amyotrophy (HP:0007149)1.79761867
95Venous insufficiency (HP:0005293)1.79624858
96Vascular tortuosity (HP:0004948)1.78909627
97Aplasia of the musculature (HP:0100854)1.77639091
98Hyperacusis (HP:0010780)1.77363691
99Osteoarthritis (HP:0002758)1.77345625
100Insulin-resistant diabetes mellitus (HP:0000831)1.77119506
101Abnormality of the acetabulum (HP:0003170)1.77049589
102Broad face (HP:0000283)1.76925752
103Abnormality of nail color (HP:0100643)1.76501550
104Rectal prolapse (HP:0002035)1.76212722
105Bronchomalacia (HP:0002780)1.75519427
106Popliteal pterygium (HP:0009756)1.75502380
107Broad ribs (HP:0000885)1.75237512
108Cardiovascular calcification (HP:0011915)1.75085480
109Milia (HP:0001056)1.74069322
110Protruding ear (HP:0000411)1.71732410
111Hip contracture (HP:0003273)1.71704779
112Inguinal hernia (HP:0000023)1.71463304
113Disproportionate tall stature (HP:0001519)1.71288102
114Broad long bones (HP:0005622)1.71036819
115Generalized amyotrophy (HP:0003700)1.70860521
116Bowed forearm bones (HP:0003956)1.70330198
117Bowing of the arm (HP:0006488)1.70330198
118Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.69237322
119Oligomenorrhea (HP:0000876)1.68634792
120Tarsal synostosis (HP:0008368)1.67356603
121Hypoventilation (HP:0002791)1.67263040
122Pterygium (HP:0001059)1.65915884
123Deformed tarsal bones (HP:0008119)1.65693374
124Abnormality of carpal bone ossification (HP:0006257)1.63817701
125Breech presentation (HP:0001623)1.63403076
126Coxa vara (HP:0002812)1.61360442
127Abnormal ossification of hand bones (HP:0005921)1.60827558
128Thin ribs (HP:0000883)1.60804593
129Achilles tendon contracture (HP:0001771)1.60393378
130Morphological abnormality of the middle ear (HP:0008609)1.59433405
131Aortic valve stenosis (HP:0001650)1.59009448
132Distal lower limb amyotrophy (HP:0008944)1.58174495
133Plantar hyperkeratosis (HP:0007556)1.57976563
134Onycholysis (HP:0001806)1.57295221

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB35.03140912
2SIK13.54633317
3DDR23.53191436
4TTN3.29506040
5PDGFRA3.26447459
6LATS13.24570020
7PKN23.05403006
8CAMK1D2.61059953
9RIPK12.59313964
10ERN12.40759787
11AKT32.21701243
12CAMK1G2.09455649
13LATS21.89239808
14FGFR21.73150555
15PRPF4B1.69100038
16EPHB21.68335498
17PTK61.66974382
18MAP3K101.49502393
19FER1.48241410
20DMPK1.46714452
21PTK21.38985503
22EPHA31.38351569
23FRK1.38084757
24PAK21.36959096
25PDGFRB1.34828446
26INSRR1.34609868
27BMX1.32790330
28TGFBR21.31024924
29MTOR1.30013496
30EEF2K1.28731253
31PRKD31.26454383
32FGFR11.23742519
33FGFR41.16990032
34MAP3K61.16201777
35FGFR31.14914659
36CDK121.09961490
37RET1.09677480
38STK31.09473724
39MET1.06743989
40LMTK21.02001703
41PAK31.01363966
42FLT31.00514179
43PIK3CA0.99483841
44LRRK20.94526842
45PRKCH0.94230444
46EPHB10.92067298
47MAPK70.91823644
48TESK10.90768578
49JAK10.90379942
50CDK60.88660810
51ICK0.86242870
52TRPM70.85645656
53PDK40.85332131
54PDK30.85332131
55MAP2K10.84622126
56SMG10.82069093
57PAK40.82028962
58MARK10.81201243
59PRKD10.80224099
60PRKD20.79987777
61ROCK10.79456775
62CDC42BPA0.74976761
63ILK0.73779610
64MAP3K20.72781058
65NEK90.72675915
66BCKDK0.72321962
67PTK2B0.71964303
68PRKAA20.69240995
69MAPK120.69042037
70PDPK10.68660047
71NTRK10.66709291
72MST1R0.63215301
73MAP3K70.63152162
74MAP3K30.61555234
75PIM20.60031979
76RPS6KC10.59825460
77RPS6KL10.59825460
78CDK90.58767428
79SGK30.56792329
80SGK4940.56763817
81SGK2230.56763817
82KIT0.56748733
83MARK20.56300159
84SCYL20.56075567
85WNK10.55549037
86MAPK150.55382169
87ABL20.55016367
88STK38L0.53236585
89MAPK110.52927480
90MAP3K130.51623004
91ARAF0.50983822
92INSR0.50324588
93PRKAA10.49967397
94DYRK1B0.48842095
95LIMK10.48688102
96ADRBK10.48553735
97GSK3A0.47735850
98MOS0.47063361
99HIPK20.45802171
100TIE10.45588952
101RPS6KA60.45325945
102PAK60.45092304
103TGFBR10.44805911
104MYLK0.44784088
105STK380.44655753
106PIK3CG0.43499272
107PRKG20.43462078
108EPHA20.43264206
109MELK0.41705852
110CAMK10.41097450
111NTRK30.40721894
112PHKG20.38470977
113PHKG10.38470977
114RPS6KA20.37988479
115TYRO30.37083483
116IGF1R0.36701979
117MAPK40.36444360
118KSR20.36314175
119SIK20.35633485
120MAPK100.35027042
121MAP3K10.34970806
122OBSCN0.34453036
123ROCK20.34129014
124CAMKK10.33745183
125MAP2K30.33395149
126RPS6KA40.32873356
127* SRC0.31870628
128PDK20.30948532
129ERBB20.30926662
130ALK0.30823103
131JAK20.28326691
132TAOK10.28309762
133MAPKAPK30.28250069

Predicted pathways (KEGG)

RankGene SetZ-score
1ECM-receptor interaction_Homo sapiens_hsa045123.24216634
2Focal adhesion_Homo sapiens_hsa045102.40023956
3Regulation of lipolysis in adipocytes_Homo sapiens_hsa049232.36252443
4Protein digestion and absorption_Homo sapiens_hsa049742.04956557
5PPAR signaling pathway_Homo sapiens_hsa033202.04656466
6Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.95923123
7Proteoglycans in cancer_Homo sapiens_hsa052051.83365815
8Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.82609088
9Dilated cardiomyopathy_Homo sapiens_hsa054141.80673256
10Adherens junction_Homo sapiens_hsa045201.75917230
11Amoebiasis_Homo sapiens_hsa051461.73995525
12Fatty acid biosynthesis_Homo sapiens_hsa000611.73115059
13Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.66394605
14Fatty acid degradation_Homo sapiens_hsa000711.61206233
15Fatty acid metabolism_Homo sapiens_hsa012121.60441554
16Glycosaminoglycan degradation_Homo sapiens_hsa005311.60098272
17Propanoate metabolism_Homo sapiens_hsa006401.55275067
18Insulin resistance_Homo sapiens_hsa049311.53563488
19Basal cell carcinoma_Homo sapiens_hsa052171.51973933
20Small cell lung cancer_Homo sapiens_hsa052221.51147407
21Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.49188091
22Adipocytokine signaling pathway_Homo sapiens_hsa049201.47213108
23Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.46183315
24AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.43029579
252-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.41951844
26AMPK signaling pathway_Homo sapiens_hsa041521.41674055
27Bladder cancer_Homo sapiens_hsa052191.39127109
28Chronic myeloid leukemia_Homo sapiens_hsa052201.32331374
29Prion diseases_Homo sapiens_hsa050201.24886845
30Other glycan degradation_Homo sapiens_hsa005111.23395924
31Nitrogen metabolism_Homo sapiens_hsa009101.22571620
32Hedgehog signaling pathway_Homo sapiens_hsa043401.22460945
33Insulin signaling pathway_Homo sapiens_hsa049101.19628216
34Lysine degradation_Homo sapiens_hsa003101.19350458
35Type II diabetes mellitus_Homo sapiens_hsa049301.19266782
36Hippo signaling pathway_Homo sapiens_hsa043901.19118555
37Longevity regulating pathway - mammal_Homo sapiens_hsa042111.17861612
38mTOR signaling pathway_Homo sapiens_hsa041501.17155814
39Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.16455003
40MicroRNAs in cancer_Homo sapiens_hsa052061.14246863
41Central carbon metabolism in cancer_Homo sapiens_hsa052301.13009717
42PI3K-Akt signaling pathway_Homo sapiens_hsa041511.10720705
43TGF-beta signaling pathway_Homo sapiens_hsa043501.08193664
44Glioma_Homo sapiens_hsa052141.07665170
45Glucagon signaling pathway_Homo sapiens_hsa049221.06470450
46Phospholipase D signaling pathway_Homo sapiens_hsa040721.04656414
47Melanoma_Homo sapiens_hsa052181.04443456
48Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.02389332
49Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.01247085
50Long-term potentiation_Homo sapiens_hsa047200.97018690
51Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.96843677
52Viral myocarditis_Homo sapiens_hsa054160.91357215
53Prostate cancer_Homo sapiens_hsa052150.90807635
54Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.90395605
55Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.87818703
56Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.83041692
57Tight junction_Homo sapiens_hsa045300.82606131
58Pathways in cancer_Homo sapiens_hsa052000.82323691
59Glycerolipid metabolism_Homo sapiens_hsa005610.82270746
60Endometrial cancer_Homo sapiens_hsa052130.81955986
61Regulation of actin cytoskeleton_Homo sapiens_hsa048100.80475316
62Pancreatic cancer_Homo sapiens_hsa052120.79941857
63Thyroid hormone signaling pathway_Homo sapiens_hsa049190.79784236
64Estrogen signaling pathway_Homo sapiens_hsa049150.79461080
65ErbB signaling pathway_Homo sapiens_hsa040120.77880100
66Toxoplasmosis_Homo sapiens_hsa051450.77729880
67Platelet activation_Homo sapiens_hsa046110.76372441
68Oxytocin signaling pathway_Homo sapiens_hsa049210.76341889
69Calcium signaling pathway_Homo sapiens_hsa040200.76198169
70Phosphatidylinositol signaling system_Homo sapiens_hsa040700.75568180
71cGMP-PKG signaling pathway_Homo sapiens_hsa040220.75511010
72Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.75437701
73Gastric acid secretion_Homo sapiens_hsa049710.74629721
74Melanogenesis_Homo sapiens_hsa049160.74140208
75Renal cell carcinoma_Homo sapiens_hsa052110.72786900
76Fat digestion and absorption_Homo sapiens_hsa049750.72034857
77Leukocyte transendothelial migration_Homo sapiens_hsa046700.71584689
78Notch signaling pathway_Homo sapiens_hsa043300.70530526
79Circadian rhythm_Homo sapiens_hsa047100.69763697
80Cocaine addiction_Homo sapiens_hsa050300.69560869
81Rap1 signaling pathway_Homo sapiens_hsa040150.69363207
82Wnt signaling pathway_Homo sapiens_hsa043100.69283045
83Inositol phosphate metabolism_Homo sapiens_hsa005620.68058180
84Arginine biosynthesis_Homo sapiens_hsa002200.67004632
85Thyroid cancer_Homo sapiens_hsa052160.66631626
86Tryptophan metabolism_Homo sapiens_hsa003800.66212655
87cAMP signaling pathway_Homo sapiens_hsa040240.65089146
88Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.64973858
89Insulin secretion_Homo sapiens_hsa049110.64436860
90Endocytosis_Homo sapiens_hsa041440.64427475
91Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.63015298
92Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.62424218
93FoxO signaling pathway_Homo sapiens_hsa040680.62175897
94Cholinergic synapse_Homo sapiens_hsa047250.61572078
95HIF-1 signaling pathway_Homo sapiens_hsa040660.61525439
96Renin secretion_Homo sapiens_hsa049240.61262542
97Choline metabolism in cancer_Homo sapiens_hsa052310.61183441
98MAPK signaling pathway_Homo sapiens_hsa040100.61126279
99Neurotrophin signaling pathway_Homo sapiens_hsa047220.59130802
100Ras signaling pathway_Homo sapiens_hsa040140.58341154
101VEGF signaling pathway_Homo sapiens_hsa043700.57453137
102Salivary secretion_Homo sapiens_hsa049700.57415910
103Non-small cell lung cancer_Homo sapiens_hsa052230.56920952
104Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.55733699
105GnRH signaling pathway_Homo sapiens_hsa049120.55713743
106Aldosterone synthesis and secretion_Homo sapiens_hsa049250.55522792
107Acute myeloid leukemia_Homo sapiens_hsa052210.55071451
108Vascular smooth muscle contraction_Homo sapiens_hsa042700.55006084
109Ovarian steroidogenesis_Homo sapiens_hsa049130.54971544
110Carbon metabolism_Homo sapiens_hsa012000.54609364
111Axon guidance_Homo sapiens_hsa043600.52291991
112Dorso-ventral axis formation_Homo sapiens_hsa043200.52168724
113Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.51977793
114Caffeine metabolism_Homo sapiens_hsa002320.51090106
115Pyruvate metabolism_Homo sapiens_hsa006200.50446883
116Thyroid hormone synthesis_Homo sapiens_hsa049180.49567488
117Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.48692926
118Complement and coagulation cascades_Homo sapiens_hsa046100.48476586
119beta-Alanine metabolism_Homo sapiens_hsa004100.47492988
120HTLV-I infection_Homo sapiens_hsa051660.46380668
121Starch and sucrose metabolism_Homo sapiens_hsa005000.46160813
122Malaria_Homo sapiens_hsa051440.45642222
123Phenylalanine metabolism_Homo sapiens_hsa003600.45102727
124Prolactin signaling pathway_Homo sapiens_hsa049170.44485767
125Bile secretion_Homo sapiens_hsa049760.44380343
126Gap junction_Homo sapiens_hsa045400.43821403

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