SHCBP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1kinetochore organization (GO:0051383)5.00525259
2CENP-A containing nucleosome assembly (GO:0034080)4.98521235
3chromatin remodeling at centromere (GO:0031055)4.83222737
4telomere maintenance via semi-conservative replication (GO:0032201)4.82659456
5DNA strand elongation involved in DNA replication (GO:0006271)4.76246452
6kinetochore assembly (GO:0051382)4.56958065
7DNA strand elongation (GO:0022616)4.55043249
8DNA replication initiation (GO:0006270)4.52475724
9regulation of mitotic spindle organization (GO:0060236)4.49624777
10telomere maintenance via recombination (GO:0000722)4.48426011
11mitotic metaphase plate congression (GO:0007080)4.46264212
12protein localization to kinetochore (GO:0034501)4.43868722
13mitotic sister chromatid cohesion (GO:0007064)4.42197201
14DNA replication checkpoint (GO:0000076)4.34095928
15mitotic recombination (GO:0006312)4.32721480
16establishment of integrated proviral latency (GO:0075713)4.27666287
17DNA replication-independent nucleosome assembly (GO:0006336)4.26710855
18DNA replication-independent nucleosome organization (GO:0034724)4.26710855
19chromosome condensation (GO:0030261)4.25500307
20positive regulation of chromosome segregation (GO:0051984)4.20735232
21attachment of spindle microtubules to kinetochore (GO:0008608)4.06416651
22metaphase plate congression (GO:0051310)4.04836059
23histone exchange (GO:0043486)4.02722405
24telomere maintenance via telomere lengthening (GO:0010833)3.95539652
25protein localization to chromosome, centromeric region (GO:0071459)3.95278407
26meiotic chromosome segregation (GO:0045132)3.90582911
27pore complex assembly (GO:0046931)3.90160786
28establishment of chromosome localization (GO:0051303)3.85377415
29DNA unwinding involved in DNA replication (GO:0006268)3.79747322
30positive regulation of mitotic sister chromatid separation (GO:1901970)3.74571299
31positive regulation of mitotic metaphase/anaphase transition (GO:0045842)3.74571299
32positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)3.74571299
33nucleotide-excision repair, DNA gap filling (GO:0006297)3.73200053
34ribosomal small subunit assembly (GO:0000028)3.72776001
35DNA deamination (GO:0045006)3.71183928
36DNA packaging (GO:0006323)3.70552579
37DNA topological change (GO:0006265)3.69136766
38mitotic sister chromatid segregation (GO:0000070)3.57439469
39maturation of SSU-rRNA (GO:0030490)3.55776309
40regulation of nuclear cell cycle DNA replication (GO:0033262)3.53345970
41regulation of DNA endoreduplication (GO:0032875)3.52481394
42regulation of sister chromatid cohesion (GO:0007063)3.52261029
43mitotic chromosome condensation (GO:0007076)3.50966360
44regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.50811187
45deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.49720458
46spindle checkpoint (GO:0031577)3.49509727
47nucleobase-containing small molecule interconversion (GO:0015949)3.48359666
48proteasome assembly (GO:0043248)3.44012385
49spindle assembly involved in mitosis (GO:0090307)3.43432464
50ribosome assembly (GO:0042255)3.43091251
51regulation of spindle organization (GO:0090224)3.40453269
52regulation of double-strand break repair via homologous recombination (GO:0010569)3.39674099
53mitotic cell cycle (GO:0000278)3.37938330
54negative regulation of mitotic sister chromatid separation (GO:2000816)3.37853919
55negative regulation of mitotic sister chromatid segregation (GO:0033048)3.37853919
56negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.37853919
57negative regulation of sister chromatid segregation (GO:0033046)3.37853919
58DNA replication-dependent nucleosome assembly (GO:0006335)3.37723934
59DNA replication-dependent nucleosome organization (GO:0034723)3.37723934
60nucleobase biosynthetic process (GO:0046112)3.37373671
61non-recombinational repair (GO:0000726)3.36386440
62double-strand break repair via nonhomologous end joining (GO:0006303)3.36386440
63spindle assembly checkpoint (GO:0071173)3.35492187
64negative regulation of chromosome segregation (GO:0051985)3.33792579
65establishment of viral latency (GO:0019043)3.30255876
66folic acid-containing compound biosynthetic process (GO:0009396)3.30140946
67negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.28207397
68sister chromatid segregation (GO:0000819)3.27837078
69purine nucleobase biosynthetic process (GO:0009113)3.27568309
70regulation of mitotic metaphase/anaphase transition (GO:0030071)3.26555306
71mitotic nuclear envelope disassembly (GO:0007077)3.26310775
72DNA conformation change (GO:0071103)3.24939310
73transcription-coupled nucleotide-excision repair (GO:0006283)3.22702250
74mitotic spindle assembly checkpoint (GO:0007094)3.21774355
75microtubule depolymerization (GO:0007019)3.20939177
76telomere maintenance (GO:0000723)3.20728791
77nuclear pore organization (GO:0006999)3.20349951
78deoxyribonucleotide biosynthetic process (GO:0009263)3.19642974
79regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.19357961
80nuclear envelope organization (GO:0006998)3.19149593
81telomere organization (GO:0032200)3.19014737
82ribosome biogenesis (GO:0042254)3.18425425
83ribosomal large subunit biogenesis (GO:0042273)3.18347323
84DNA duplex unwinding (GO:0032508)3.17723785
85IMP biosynthetic process (GO:0006188)3.17068875
86microtubule cytoskeleton organization involved in mitosis (GO:1902850)3.17030337
87regulation of chromosome segregation (GO:0051983)3.16098503
88protein K6-linked ubiquitination (GO:0085020)3.16082844
89mitotic spindle checkpoint (GO:0071174)3.15888192
90anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.15799374
91regulation of sister chromatid segregation (GO:0033045)3.12587882
92regulation of mitotic sister chromatid separation (GO:0010965)3.12587882
93regulation of mitotic sister chromatid segregation (GO:0033047)3.12587882
94mismatch repair (GO:0006298)3.11579367
95formation of translation preinitiation complex (GO:0001731)3.10224880
96DNA ligation (GO:0006266)3.10139311
97ribonucleoprotein complex biogenesis (GO:0022613)3.09662382
98regulation of centriole replication (GO:0046599)3.09622774
99DNA geometric change (GO:0032392)3.09383104
100negative regulation of DNA-dependent DNA replication (GO:2000104)3.08918874
101regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.08918287
102spliceosomal snRNP assembly (GO:0000387)3.08813134
103regulation of centrosome cycle (GO:0046605)3.07346061
104negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.07272885
105nuclear pore complex assembly (GO:0051292)3.05550138
106mitotic spindle organization (GO:0007052)3.04188629
107chromosome segregation (GO:0007059)3.03931789
108regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450913.03913199
109maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.03014486
110mitotic cytokinesis (GO:0000281)3.02895689
111rRNA modification (GO:0000154)3.02271676
112ATP-dependent chromatin remodeling (GO:0043044)3.00857898
113regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.98972375
114positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.97333843
115viral mRNA export from host cell nucleus (GO:0046784)2.97066639
116nuclear envelope disassembly (GO:0051081)2.95384054
117membrane disassembly (GO:0030397)2.95384054
118rRNA processing (GO:0006364)2.93559832
119regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.93234658
120regulation of mitotic spindle checkpoint (GO:1903504)2.93234658
121DNA double-strand break processing (GO:0000729)2.92864323
122chromatin assembly or disassembly (GO:0006333)2.92781812
123G1/S transition of mitotic cell cycle (GO:0000082)2.92532149
124cell cycle G1/S phase transition (GO:0044843)2.92532149
125protein localization to chromosome (GO:0034502)2.91510893
126DNA synthesis involved in DNA repair (GO:0000731)2.91146858
127somatic hypermutation of immunoglobulin genes (GO:0016446)2.89247390

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.58248423
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.94452357
3* E2F4_17652178_ChIP-ChIP_JURKAT_Human4.46484356
4MYC_18555785_ChIP-Seq_MESCs_Mouse4.00769422
5FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.79961006
6KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.74722277
7EST1_17652178_ChIP-ChIP_JURKAT_Human3.14013150
8GABP_17652178_ChIP-ChIP_JURKAT_Human3.01823995
9JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.81099762
10EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.80266996
11MYC_19030024_ChIP-ChIP_MESCs_Mouse2.74731384
12MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.73439530
13MYC_19079543_ChIP-ChIP_MESCs_Mouse2.67414584
14MYC_18358816_ChIP-ChIP_MESCs_Mouse2.62651992
15ETS1_20019798_ChIP-Seq_JURKAT_Human2.62273135
16CREB1_15753290_ChIP-ChIP_HEK293T_Human2.50449788
17HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.47730129
18ELF1_17652178_ChIP-ChIP_JURKAT_Human2.42567959
19MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.37566228
20CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.35963892
21VDR_23849224_ChIP-Seq_CD4+_Human2.31383080
22AR_21909140_ChIP-Seq_LNCAP_Human2.28719270
23MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.27556242
24NELFA_20434984_ChIP-Seq_ESCs_Mouse2.26843023
25NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.17711850
26CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.14766533
27E2F1_21310950_ChIP-Seq_MCF-7_Human2.09169609
28XRN2_22483619_ChIP-Seq_HELA_Human2.09064847
29ELK1_19687146_ChIP-ChIP_HELA_Human2.06852447
30SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.06814398
31FOXP3_21729870_ChIP-Seq_TREG_Human2.04423671
32* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.03852515
33KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.89131221
34* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.88007725
35E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.87616079
36DCP1A_22483619_ChIP-Seq_HELA_Human1.87346751
37HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.86359883
38TTF2_22483619_ChIP-Seq_HELA_Human1.85409906
39PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.80709007
40MYCN_18555785_ChIP-Seq_MESCs_Mouse1.75585753
41FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.74967548
42TP63_19390658_ChIP-ChIP_HaCaT_Human1.72758287
43NANOG_18555785_ChIP-Seq_MESCs_Mouse1.72239068
44SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.71769937
45YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.65457637
46GABP_19822575_ChIP-Seq_HepG2_Human1.65381935
47HOXB4_20404135_ChIP-ChIP_EML_Mouse1.65294201
48TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.63766692
49THAP11_20581084_ChIP-Seq_MESCs_Mouse1.61341906
50SRF_21415370_ChIP-Seq_HL-1_Mouse1.53241921
51ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.52945531
52YY1_21170310_ChIP-Seq_MESCs_Mouse1.49448973
53PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.42628708
54POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.42617383
55DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.42460353
56CIITA_25753668_ChIP-Seq_RAJI_Human1.38955368
57TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.38261752
58POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.36692374
59PADI4_21655091_ChIP-ChIP_MCF-7_Human1.29262387
60FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.27629329
61EGR1_19374776_ChIP-ChIP_THP-1_Human1.24038505
62ERG_20887958_ChIP-Seq_HPC-7_Mouse1.22109669
63SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.21397773
64CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.19813716
65NOTCH1_21737748_ChIP-Seq_TLL_Human1.18537003
66ZFX_18555785_ChIP-Seq_MESCs_Mouse1.18499891
67MYC_18940864_ChIP-ChIP_HL60_Human1.16162262
68* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.14901778
69SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.13889115
70KDM5A_27292631_Chip-Seq_BREAST_Human1.12271188
71RBPJ_22232070_ChIP-Seq_NCS_Mouse1.11585013
72SOX2_18555785_ChIP-Seq_MESCs_Mouse1.11056033
73ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.09401629
74MYC_22102868_ChIP-Seq_BL_Human1.08833902
75* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.08098389
76SALL1_21062744_ChIP-ChIP_HESCs_Human1.05868905
77CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.05835585
78ZNF263_19887448_ChIP-Seq_K562_Human1.02305217
79SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.01029506
80KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.00407248
81PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.98984958
82SPI1_23547873_ChIP-Seq_NB4_Human0.95756131
83CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.94685016
84SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.94535506
85IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.91701682
86ESR1_15608294_ChIP-ChIP_MCF-7_Human0.91329363
87IRF1_19129219_ChIP-ChIP_H3396_Human0.91213593
88CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.89717170
89GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.87136052
90ELK1_22589737_ChIP-Seq_MCF10A_Human0.83350265
91TBX5_21415370_ChIP-Seq_HL-1_Mouse0.81402985
92NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.80490609
93STAT3_1855785_ChIP-Seq_MESCs_Mouse0.78698338
94NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.77928041
95CHD1_26751641_Chip-Seq_LNCaP_Human0.77818979
96TFEB_21752829_ChIP-Seq_HELA_Human0.76778499
97CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.76644228
98* SOX17_20123909_ChIP-Seq_XEN_Mouse0.73939756
99KLF4_18555785_ChIP-Seq_MESCs_Mouse0.73458487
100NANOG_16153702_ChIP-ChIP_HESCs_Human0.72764158
101POU5F1_16153702_ChIP-ChIP_HESCs_Human0.72491030
102IRF8_21731497_ChIP-ChIP_J774_Mouse0.72427299
103CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.72409750
104* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.72131007
105TRIM28_19339689_ChIP-ChIP_MESCs_Mouse0.72011773
106BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.71968577
107NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.70378073
108EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.68511365
109HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.68328665
110CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.66954958
111KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.65640923
112GATA4_21415370_ChIP-Seq_HL-1_Mouse0.64943304
113KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.64178301
114KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.64178301
115KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.64178301
116SOX2_16153702_ChIP-ChIP_HESCs_Human0.62046509
117KAP1_22055183_ChIP-Seq_ESCs_Mouse0.61982918
118POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.61829455
119FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.60963140

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.40165692
2MP0010094_abnormal_chromosome_stability4.92198597
3MP0003111_abnormal_nucleus_morphology4.56468832
4MP0008057_abnormal_DNA_replication4.02719101
5MP0003077_abnormal_cell_cycle3.92637202
6MP0004957_abnormal_blastocyst_morpholog3.87977875
7MP0008058_abnormal_DNA_repair3.85890970
8MP0008007_abnormal_cellular_replicative2.91871574
9MP0002877_abnormal_melanocyte_morpholog2.89435352
10MP0008932_abnormal_embryonic_tissue2.69969000
11MP0008877_abnormal_DNA_methylation2.56802107
12MP0003950_abnormal_plasma_membrane2.47606498
13MP0003786_premature_aging2.24338531
14MP0002396_abnormal_hematopoietic_system2.17629572
15MP0006292_abnormal_olfactory_placode2.08702642
16MP0003705_abnormal_hypodermis_morpholog1.96592686
17MP0003718_maternal_effect1.82528520
18MP0003941_abnormal_skin_development1.73511772
19MP0003123_paternal_imprinting1.72869703
20MP0000350_abnormal_cell_proliferation1.72518383
21MP0003806_abnormal_nucleotide_metabolis1.69741180
22MP0000490_abnormal_crypts_of1.66978852
23MP0005623_abnormal_meninges_morphology1.62479596
24MP0001730_embryonic_growth_arrest1.58462289
25MP0000566_synostosis1.56322848
26MP0010307_abnormal_tumor_latency1.45757486
27MP0002210_abnormal_sex_determination1.45513691
28MP0003315_abnormal_perineum_morphology1.43536234
29MP0004808_abnormal_hematopoietic_stem1.41132658
30MP0000313_abnormal_cell_death1.36700889
31MP0008438_abnormal_cutaneous_collagen1.35325780
32MP0003566_abnormal_cell_adhesion1.33685834
33MP0000358_abnormal_cell_content/1.31721349
34MP0001188_hyperpigmentation1.31250588
35MP0002132_abnormal_respiratory_system1.28578792
36MP0001672_abnormal_embryogenesis/_devel1.26482262
37MP0005380_embryogenesis_phenotype1.26482262
38MP0002019_abnormal_tumor_incidence1.25979630
39MP0003121_genomic_imprinting1.23408574
40MP0001697_abnormal_embryo_size1.21672794
41MP0002102_abnormal_ear_morphology1.19938998
42MP0003763_abnormal_thymus_physiology1.19633025
43MP0001145_abnormal_male_reproductive1.19597505
44MP0004233_abnormal_muscle_weight1.19229316
45MP0002160_abnormal_reproductive_system1.18413254
46MP0005076_abnormal_cell_differentiation1.18411679
47MP0001929_abnormal_gametogenesis1.17029092
48MP0010234_abnormal_vibrissa_follicle1.16536408
49MP0010352_gastrointestinal_tract_polyps1.16076127
50MP0010030_abnormal_orbit_morphology1.15594423
51MP0003136_yellow_coat_color1.15490834
52MP0002085_abnormal_embryonic_tissue1.13901072
53MP0009697_abnormal_copulation1.12923777
54MP0002095_abnormal_skin_pigmentation1.12711289
55MP0005389_reproductive_system_phenotype1.12551510
56MP0009333_abnormal_splenocyte_physiolog1.11943860
57MP0002080_prenatal_lethality1.11817001
58MP0001293_anophthalmia1.10961467
59MP0005408_hypopigmentation1.10005871
60MP0000015_abnormal_ear_pigmentation1.09681873
61MP0001119_abnormal_female_reproductive1.09201119
62MP0000703_abnormal_thymus_morphology1.06858900
63MP0000653_abnormal_sex_gland1.06110459
64MP0003890_abnormal_embryonic-extraembry1.04110013
65MP0005075_abnormal_melanosome_morpholog1.03456567
66MP0005621_abnormal_cell_physiology1.03257157
67MP0002398_abnormal_bone_marrow1.03200477
68MP0003984_embryonic_growth_retardation1.02524195
69MP0005174_abnormal_tail_pigmentation1.01129254
70MP0001986_abnormal_taste_sensitivity1.00986046
71MP0005501_abnormal_skin_physiology1.00669313
72MP0006035_abnormal_mitochondrial_morpho1.00190113
73MP0003567_abnormal_fetal_cardiomyocyte0.99468072
74MP0002277_abnormal_respiratory_mucosa0.98966176
75MP0002088_abnormal_embryonic_growth/wei0.98438413
76MP0002722_abnormal_immune_system0.96161214
77MP0001835_abnormal_antigen_presentation0.95199064
78MP0001661_extended_life_span0.94502349
79MP0002938_white_spotting0.93994891
80MP0005257_abnormal_intraocular_pressure0.93632432
81MP0003937_abnormal_limbs/digits/tail_de0.93284861
82MP0002084_abnormal_developmental_patter0.92944947
83MP0004185_abnormal_adipocyte_glucose0.92637693
84MP0001853_heart_inflammation0.91844365
85MP0000689_abnormal_spleen_morphology0.90787800
86MP0002060_abnormal_skin_morphology0.90420578
87MP0002086_abnormal_extraembryonic_tissu0.89117323
88MP0009379_abnormal_foot_pigmentation0.88732632
89MP0001919_abnormal_reproductive_system0.88361158
90MP0005395_other_phenotype0.87367871
91MP0004133_heterotaxia0.87285407
92MP0009672_abnormal_birth_weight0.86830547
93MP0004197_abnormal_fetal_growth/weight/0.85793943
94MP0003186_abnormal_redox_activity0.85131064
95MP0005171_absent_coat_pigmentation0.84271393
96MP0000372_irregular_coat_pigmentation0.82795735
97MP0005397_hematopoietic_system_phenotyp0.82677542
98MP0001545_abnormal_hematopoietic_system0.82677542
99MP0000858_altered_metastatic_potential0.80724541
100MP0002429_abnormal_blood_cell0.78675088
101MP0005671_abnormal_response_to0.77753836
102MP0001243_abnormal_dermal_layer0.76715074
103MP0000049_abnormal_middle_ear0.75341141
104MP0004381_abnormal_hair_follicle0.74686248
105MP0003699_abnormal_female_reproductive0.73779955
106MP0000716_abnormal_immune_system0.73494729
107MP0001286_abnormal_eye_development0.73362175
108MP0002111_abnormal_tail_morphology0.71805465
109MP0003698_abnormal_male_reproductive0.71257692
110MP0002697_abnormal_eye_size0.70842863
111MP0001186_pigmentation_phenotype0.70021275
112MP0003656_abnormal_erythrocyte_physiolo0.69955629
113MP0003943_abnormal_hepatobiliary_system0.68214818
114MP0002148_abnormal_hypersensitivity_rea0.67911378
115MP0001800_abnormal_humoral_immune0.67689961
116MP0002075_abnormal_coat/hair_pigmentati0.67208138
117MP0005023_abnormal_wound_healing0.67185845
118MP0002452_abnormal_antigen_presenting0.66770125
119MP0002420_abnormal_adaptive_immunity0.66273702
120MP0008995_early_reproductive_senescence0.66222756
121MP0001819_abnormal_immune_cell0.65649313
122MP0003221_abnormal_cardiomyocyte_apopto0.63977022
123MP0001881_abnormal_mammary_gland0.63616282
124MP0002177_abnormal_outer_ear0.63203908
125MP0005451_abnormal_body_composition0.62319973
126MP0004272_abnormal_basement_membrane0.62185988
127MP0000428_abnormal_craniofacial_morphol0.61655527
128MP0002269_muscular_atrophy0.61412785
129MP0001348_abnormal_lacrimal_gland0.61373729
130MP0000627_abnormal_mammary_gland0.61335194
131MP0003787_abnormal_imprinting0.60616408
132MP0006036_abnormal_mitochondrial_physio0.59912076
133MP0009785_altered_susceptibility_to0.59423733
134MP0002006_tumorigenesis0.59233416
135MP0000383_abnormal_hair_follicle0.58371111
136MP0002161_abnormal_fertility/fecundity0.58236368
137MP0002092_abnormal_eye_morphology0.57893249
138MP0000537_abnormal_urethra_morphology0.57584323
139MP0000432_abnormal_head_morphology0.57207968
140MP0002723_abnormal_immune_serum0.56193189
141MP0005384_cellular_phenotype0.55610364
142MP0006054_spinal_hemorrhage0.55559989
143MP0002163_abnormal_gland_morphology0.55558588
144MP0000733_abnormal_muscle_development0.55536965
145MP0001216_abnormal_epidermal_layer0.54846723
146MP0003755_abnormal_palate_morphology0.54815942
147MP0001346_abnormal_lacrimal_gland0.53500710

Predicted human phenotypes

RankGene SetZ-score
1Chromosomal breakage induced by crosslinking agents (HP:0003221)5.46984228
2Chromsome breakage (HP:0040012)5.46726155
3Birth length less than 3rd percentile (HP:0003561)4.46599396
4Reticulocytopenia (HP:0001896)4.22504493
5Meckel diverticulum (HP:0002245)4.00612953
6Abnormality of the preputium (HP:0100587)4.00341398
7Abnormality of chromosome stability (HP:0003220)3.89350731
8Abnormality of the ileum (HP:0001549)3.78549219
9Aplasia/Hypoplasia of the uvula (HP:0010293)3.71823388
10Duplicated collecting system (HP:0000081)3.53603363
11Breast hypoplasia (HP:0003187)3.39247263
12Small intestinal stenosis (HP:0012848)3.27847707
13Duodenal stenosis (HP:0100867)3.27847707
14Abnormality of the renal collecting system (HP:0004742)3.25398306
15Patellar aplasia (HP:0006443)3.08771277
16Ectopic kidney (HP:0000086)2.97637543
17Myelodysplasia (HP:0002863)2.97143694
18Absent thumb (HP:0009777)2.95677995
19Absent radius (HP:0003974)2.93589493
20Abnormal lung lobation (HP:0002101)2.92244795
21Aplasia/Hypoplasia of the patella (HP:0006498)2.88410629
22Clubbing of toes (HP:0100760)2.85801397
23Bone marrow hypocellularity (HP:0005528)2.84409973
24Impulsivity (HP:0100710)2.84252321
25Abnormal number of erythroid precursors (HP:0012131)2.80184733
26Aplastic anemia (HP:0001915)2.74997532
27Abnormality of cells of the erythroid lineage (HP:0012130)2.74159851
28Aplasia involving forearm bones (HP:0009822)2.73830805
29Absent forearm bone (HP:0003953)2.73830805
30Oral leukoplakia (HP:0002745)2.72825394
31Selective tooth agenesis (HP:0001592)2.72394707
32Abnormality of the duodenum (HP:0002246)2.68473115
33Colon cancer (HP:0003003)2.68137108
34Supernumerary spleens (HP:0009799)2.60592233
35Triphalangeal thumb (HP:0001199)2.59610558
36Entropion (HP:0000621)2.59541151
37Sloping forehead (HP:0000340)2.58976007
38Poikiloderma (HP:0001029)2.56931048
39Cafe-au-lait spot (HP:0000957)2.54787971
40Abnormality of DNA repair (HP:0003254)2.54779768
41Premature rupture of membranes (HP:0001788)2.54579834
42Ankle contracture (HP:0006466)2.52399417
43Carpal bone hypoplasia (HP:0001498)2.48167458
4411 pairs of ribs (HP:0000878)2.46749741
45Abnormality of the carotid arteries (HP:0005344)2.46676690
46Nephroblastoma (Wilms tumor) (HP:0002667)2.44096687
47Premature graying of hair (HP:0002216)2.43761327
48Medulloblastoma (HP:0002885)2.43124173
49Proximal placement of thumb (HP:0009623)2.41137757
50Deviation of the thumb (HP:0009603)2.40672261
51Aplasia/Hypoplasia of the sacrum (HP:0008517)2.40139935
52Rough bone trabeculation (HP:0100670)2.38560134
53Abnormality of glycolysis (HP:0004366)2.37422805
54Horseshoe kidney (HP:0000085)2.33307591
55Agnosia (HP:0010524)2.29480591
56Overlapping toe (HP:0001845)2.28161394
57Abnormality of the umbilical cord (HP:0010881)2.28037456
58Embryonal renal neoplasm (HP:0011794)2.27672239
59Pallor (HP:0000980)2.27617790
60Type I transferrin isoform profile (HP:0003642)2.26243462
61Cortical dysplasia (HP:0002539)2.25997347
62Short thumb (HP:0009778)2.23658272
63Ependymoma (HP:0002888)2.21414206
64Tracheoesophageal fistula (HP:0002575)2.21172928
65Progressive muscle weakness (HP:0003323)2.15600163
66Cleft eyelid (HP:0000625)2.13225087
67Cutaneous melanoma (HP:0012056)2.12584854
68Abnormal umbilical cord blood vessels (HP:0011403)2.11585462
69Single umbilical artery (HP:0001195)2.11585462
70Abnormality of the fetal cardiovascular system (HP:0010948)2.11585462
71Secondary amenorrhea (HP:0000869)2.10068055
72Increased serum pyruvate (HP:0003542)2.09205153
73Degeneration of anterior horn cells (HP:0002398)2.07586782
74Abnormality of the anterior horn cell (HP:0006802)2.07586782
75Deep philtrum (HP:0002002)2.07143622
76Choanal atresia (HP:0000453)2.07039622
77Macrocytic anemia (HP:0001972)2.04371649
78Pancytopenia (HP:0001876)2.03622096
79Type 2 muscle fiber atrophy (HP:0003554)2.02550773
80Microglossia (HP:0000171)2.01011473
81Abnormal number of incisors (HP:0011064)2.00039098
82Trismus (HP:0000211)1.98492744
83Neoplasm of the pancreas (HP:0002894)1.97618492
84Lymphoma (HP:0002665)1.93720607
85Multiple enchondromatosis (HP:0005701)1.93662476
86Abnormal trabecular bone morphology (HP:0100671)1.92398370
87Abnormal spermatogenesis (HP:0008669)1.92144339
88Aplasia/Hypoplasia of the earlobes (HP:0009906)1.88122751
89Abnormal auditory evoked potentials (HP:0006958)1.87594293
90Ureteral duplication (HP:0000073)1.87227983
91Microretrognathia (HP:0000308)1.86765481
92Muscle fiber atrophy (HP:0100295)1.86258342
93Facial hemangioma (HP:0000329)1.86053041
94Abnormality of chromosome segregation (HP:0002916)1.86010008
95Reduced subcutaneous adipose tissue (HP:0003758)1.85151377
96Cellular immunodeficiency (HP:0005374)1.83359629
97Optic nerve coloboma (HP:0000588)1.82957515
98Orthostatic hypotension (HP:0001278)1.82900769
99Duplication of thumb phalanx (HP:0009942)1.82486187
100Facial cleft (HP:0002006)1.82299152
101Hypoplastic pelvis (HP:0008839)1.81845197
102Increased nuchal translucency (HP:0010880)1.81797657
103Hypoplasia of the capital femoral epiphysis (HP:0003090)1.80712874
104Cholecystitis (HP:0001082)1.78704815
105Abnormal gallbladder physiology (HP:0012438)1.78704815
106Prominent nose (HP:0000448)1.77672464
107High pitched voice (HP:0001620)1.77619114
108Astrocytoma (HP:0009592)1.75859749
109Abnormality of the astrocytes (HP:0100707)1.75859749
110Glioma (HP:0009733)1.75144443
111Abnormality of pyrimidine metabolism (HP:0004353)1.74602304
112Embryonal neoplasm (HP:0002898)1.74492388
113Insomnia (HP:0100785)1.73557909
114Hyperacusis (HP:0010780)1.73451461
115Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.72371975
116Hypoplasia of the radius (HP:0002984)1.72350621
117Capillary hemangiomas (HP:0005306)1.71166671
118IgM deficiency (HP:0002850)1.70991470
119Volvulus (HP:0002580)1.70816440
120Neoplasm of the colon (HP:0100273)1.70183535
121Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.69343925
122Abnormalities of placenta or umbilical cord (HP:0001194)1.68760861
123Osteolytic defects of the hand bones (HP:0009699)1.68484514
124Osteolytic defects of the phalanges of the hand (HP:0009771)1.68484514
125Sparse eyelashes (HP:0000653)1.68119747
126Microvesicular hepatic steatosis (HP:0001414)1.68109842
127Leukopenia (HP:0001882)1.67679313
128Elbow flexion contracture (HP:0002987)1.67514490
129Abnormality of the labia minora (HP:0012880)1.67196621
130Pancreatic cysts (HP:0001737)1.66389791
131Shoulder girdle muscle weakness (HP:0003547)1.66307242
132Upper limb muscle weakness (HP:0003484)1.65446170
133Small epiphyses (HP:0010585)1.64680415
134Asplenia (HP:0001746)1.64366954
135Hypergonadotropic hypogonadism (HP:0000815)1.63766071
136Atresia of the external auditory canal (HP:0000413)1.63651914
137Cerebral hypomyelination (HP:0006808)1.63386187
138Progressive external ophthalmoplegia (HP:0000590)1.63112297
139Arteriovenous malformation (HP:0100026)1.61396859
140Preaxial hand polydactyly (HP:0001177)1.59340802
141Aplasia/Hypoplasia of the sternum (HP:0006714)1.56568068
142Granulocytopenia (HP:0001913)1.56189051
143Amaurosis fugax (HP:0100576)1.55943855
144True hermaphroditism (HP:0010459)1.54115422
145Rhabdomyosarcoma (HP:0002859)1.53764640
146Squamous cell carcinoma (HP:0002860)1.53741871
147Hypopigmented skin patches (HP:0001053)1.52520371
148Reduced antithrombin III activity (HP:0001976)1.52170611
149Oligohydramnios (HP:0001562)1.52110488
150Pancreatic fibrosis (HP:0100732)1.52014207

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.89179478
2WEE14.10954547
3CDC73.67782293
4PLK43.52556072
5STK163.20299158
6SRPK12.91432827
7TTK2.66310671
8EIF2AK12.65087241
9ZAK2.60142213
10BRSK22.43443858
11NEK22.29976418
12MKNK12.19692572
13PLK12.10780743
14VRK12.08479170
15ACVR1B1.92085967
16EIF2AK31.88726061
17CCNB11.88619571
18PLK31.85369752
19VRK21.85364464
20IRAK31.82273524
21MKNK21.78147879
22AURKB1.74004793
23TSSK61.72239308
24ATR1.71080009
25MST1R1.70867047
26CHEK21.56947903
27IRAK41.56393148
28SCYL21.55646427
29NEK11.54478260
30EIF2AK21.54029162
31PBK1.45604639
32DYRK31.43299948
33CDK71.43252550
34BRSK11.42793770
35TLK11.40812903
36NME21.33208998
37STK41.32702776
38PASK1.32187827
39SMG11.23638590
40TESK21.22166803
41TAF11.19634223
42RPS6KA41.18815530
43AURKA1.16329875
44EPHA21.13977784
45ERBB41.10762719
46MET1.10685158
47RPS6KB21.01140920
48TRIM281.00176983
49CHEK11.00156649
50CDK80.99048633
51STK100.98734429
52MAP3K80.91881814
53CLK10.86760460
54CDK40.85867464
55ATM0.81826425
56TXK0.78719359
57BRD40.78616641
58YES10.77903558
59BRAF0.77708344
60PDK20.77435059
61LATS20.77403817
62TGFBR10.76173617
63BLK0.73243358
64TEC0.72507035
65PIM10.72464750
66CSNK2A10.68037535
67LATS10.65860164
68MST40.65422953
69ARAF0.65302233
70CDK20.65124630
71RPS6KA50.63388368
72LIMK10.61913815
73NUAK10.60493155
74PTK20.59551569
75CDK10.58579537
76MELK0.58111157
77PAK40.57410837
78MAP3K100.57064965
79CSNK2A20.53905411
80PIM20.51166481
81ICK0.50929855
82CDK120.50892721
83PRKCI0.50088370
84TESK10.49931193
85MOS0.49799396
86PNCK0.49030073
87PAK20.49000363
88KDR0.47932537
89CDK90.46817619
90AKT20.46493485
91EEF2K0.46485408
92BTK0.46316664
93IRAK10.45891221
94AKT30.45453686
95MAP3K140.45406466
96ERBB30.44138530
97CDK60.44132941
98TTN0.44067054
99MAP4K10.43857729
100MAPK110.43222895
101PAK10.42918993
102STK30.42743121
103CDK180.42609899
104BMPR1B0.41403293
105STK38L0.40631852
106NEK60.40316416
107CDK150.40310350
108CDK11A0.39781449
109ALK0.39347642
110MARK30.37847494
111IKBKB0.36431513
112RAF10.36429612
113CDK140.35330503
114NEK90.35032304
115LYN0.34521580
116DYRK20.33247212
117ADRBK20.32899431
118CDK30.30690201
119IRAK20.29496707
120PDGFRA0.27655300
121CHUK0.25100479
122PRKDC0.24248372
123KIT0.24005532
124DAPK10.23934990
125PLK20.23579160
126ILK0.23234245
127MTOR0.22597781
128NLK0.22542309
129KSR10.20169393
130SIK30.18324464
131MAPK140.18139457
132JAK30.17110790
133NME10.16149463
134TAOK20.15904701
135AKT10.15373074

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030305.03768150
2Mismatch repair_Homo sapiens_hsa034304.36137845
3Homologous recombination_Homo sapiens_hsa034403.43318413
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.31613420
5Proteasome_Homo sapiens_hsa030503.31234598
6RNA polymerase_Homo sapiens_hsa030203.17905943
7Spliceosome_Homo sapiens_hsa030403.10850488
8Fanconi anemia pathway_Homo sapiens_hsa034603.09120180
9Base excision repair_Homo sapiens_hsa034103.07438196
10Ribosome_Homo sapiens_hsa030103.05710663
11Nucleotide excision repair_Homo sapiens_hsa034202.95746386
12Cell cycle_Homo sapiens_hsa041102.76735433
13RNA transport_Homo sapiens_hsa030132.69160619
14Pyrimidine metabolism_Homo sapiens_hsa002402.58610373
15Non-homologous end-joining_Homo sapiens_hsa034502.37838012
16One carbon pool by folate_Homo sapiens_hsa006702.24187103
17Basal transcription factors_Homo sapiens_hsa030222.20143889
18Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.09493736
19RNA degradation_Homo sapiens_hsa030181.92864272
20p53 signaling pathway_Homo sapiens_hsa041151.70456128
21Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.70302741
22Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.55863197
23Purine metabolism_Homo sapiens_hsa002301.49941057
24mRNA surveillance pathway_Homo sapiens_hsa030151.45151288
25Biosynthesis of amino acids_Homo sapiens_hsa012301.39249893
26Systemic lupus erythematosus_Homo sapiens_hsa053221.29299503
27Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.27224144
28Epstein-Barr virus infection_Homo sapiens_hsa051691.17230576
29Carbon metabolism_Homo sapiens_hsa012001.03589071
30Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.02743580
31Herpes simplex infection_Homo sapiens_hsa051681.02504467
322-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.01683858
33Protein export_Homo sapiens_hsa030600.99189745
34Pyruvate metabolism_Homo sapiens_hsa006200.98056343
35Sulfur relay system_Homo sapiens_hsa041220.95272887
36Antigen processing and presentation_Homo sapiens_hsa046120.87052770
37Primary immunodeficiency_Homo sapiens_hsa053400.84548132
38Oocyte meiosis_Homo sapiens_hsa041140.84048178
39Viral carcinogenesis_Homo sapiens_hsa052030.80969062
40Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.80685331
41Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.80136732
42Bladder cancer_Homo sapiens_hsa052190.77223161
43Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.75850133
44Fatty acid elongation_Homo sapiens_hsa000620.74348713
45Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.73774265
46Huntingtons disease_Homo sapiens_hsa050160.72841094
47NF-kappa B signaling pathway_Homo sapiens_hsa040640.71138396
48Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.70800741
49HTLV-I infection_Homo sapiens_hsa051660.70078202
50Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.69898894
51Central carbon metabolism in cancer_Homo sapiens_hsa052300.67460190
52Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.66717168
53Vitamin B6 metabolism_Homo sapiens_hsa007500.66477950
54Legionellosis_Homo sapiens_hsa051340.61886267
55Measles_Homo sapiens_hsa051620.61653978
56Allograft rejection_Homo sapiens_hsa053300.58380349
57Arachidonic acid metabolism_Homo sapiens_hsa005900.57633372
58Steroid biosynthesis_Homo sapiens_hsa001000.56627772
59Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.55325664
60Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.55122694
61Lysine degradation_Homo sapiens_hsa003100.55085921
62Hematopoietic cell lineage_Homo sapiens_hsa046400.54698789
63Intestinal immune network for IgA production_Homo sapiens_hsa046720.54155416
64Pancreatic cancer_Homo sapiens_hsa052120.52990792
65Asthma_Homo sapiens_hsa053100.52957580
66Graft-versus-host disease_Homo sapiens_hsa053320.52909729
67Folate biosynthesis_Homo sapiens_hsa007900.52376567
68Transcriptional misregulation in cancer_Homo sapiens_hsa052020.52211930
69Drug metabolism - other enzymes_Homo sapiens_hsa009830.51432508
70Autoimmune thyroid disease_Homo sapiens_hsa053200.51329775
71Chronic myeloid leukemia_Homo sapiens_hsa052200.51303258
72Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.49907091
73Parkinsons disease_Homo sapiens_hsa050120.49348716
74Small cell lung cancer_Homo sapiens_hsa052220.49231909
75Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.47673753
76Glutathione metabolism_Homo sapiens_hsa004800.47509305
77MicroRNAs in cancer_Homo sapiens_hsa052060.46183301
78Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.46083974
79Pentose phosphate pathway_Homo sapiens_hsa000300.45811336
80NOD-like receptor signaling pathway_Homo sapiens_hsa046210.45366451
81Adherens junction_Homo sapiens_hsa045200.44969864
82Prostate cancer_Homo sapiens_hsa052150.44736294
83Apoptosis_Homo sapiens_hsa042100.43266645
84Selenocompound metabolism_Homo sapiens_hsa004500.42324590
85Melanoma_Homo sapiens_hsa052180.42034972
86RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.41899080
87Galactose metabolism_Homo sapiens_hsa000520.40577062
88Alcoholism_Homo sapiens_hsa050340.40098751
89Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.37851985
90Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.36779627
91Cysteine and methionine metabolism_Homo sapiens_hsa002700.35448275
92Propanoate metabolism_Homo sapiens_hsa006400.35088878
93Oxidative phosphorylation_Homo sapiens_hsa001900.34981587
94N-Glycan biosynthesis_Homo sapiens_hsa005100.34122788
95Sulfur metabolism_Homo sapiens_hsa009200.33344664
96Influenza A_Homo sapiens_hsa051640.31709420
97Proteoglycans in cancer_Homo sapiens_hsa052050.31447269
98Hepatitis B_Homo sapiens_hsa051610.31341751
99Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.30449364
100Non-small cell lung cancer_Homo sapiens_hsa052230.29312078
101Basal cell carcinoma_Homo sapiens_hsa052170.28423107
102TGF-beta signaling pathway_Homo sapiens_hsa043500.28154698
103Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.27735648
104Cyanoamino acid metabolism_Homo sapiens_hsa004600.27656813
105Shigellosis_Homo sapiens_hsa051310.26207408
106Renin-angiotensin system_Homo sapiens_hsa046140.26027384
107Metabolic pathways_Homo sapiens_hsa011000.23733448
108Other glycan degradation_Homo sapiens_hsa005110.23431201
109Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.23127316
110SNARE interactions in vesicular transport_Homo sapiens_hsa041300.21386210
111Pathways in cancer_Homo sapiens_hsa052000.19638352
112Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.19261088
113Linoleic acid metabolism_Homo sapiens_hsa005910.19102119
114Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.18950324
115Hippo signaling pathway_Homo sapiens_hsa043900.18235491
116Leishmaniasis_Homo sapiens_hsa051400.18146472
117Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.16308655
118Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.15668039
119Thyroid cancer_Homo sapiens_hsa052160.15538196
120Jak-STAT signaling pathway_Homo sapiens_hsa046300.15171772
121Regulation of actin cytoskeleton_Homo sapiens_hsa048100.15095745
122Sphingolipid metabolism_Homo sapiens_hsa006000.14357980
123Focal adhesion_Homo sapiens_hsa045100.13676073
124Regulation of autophagy_Homo sapiens_hsa041400.13307753
125Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.13178670
126Viral myocarditis_Homo sapiens_hsa054160.12928729
127PI3K-Akt signaling pathway_Homo sapiens_hsa041510.12881762
128Colorectal cancer_Homo sapiens_hsa052100.12503439
129Vibrio cholerae infection_Homo sapiens_hsa051100.12040686
130Type I diabetes mellitus_Homo sapiens_hsa049400.12035439
131ECM-receptor interaction_Homo sapiens_hsa045120.11654511
132Phototransduction_Homo sapiens_hsa047440.11498564
133Notch signaling pathway_Homo sapiens_hsa043300.11279789
134Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.10812942
135Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.09901652
136Hedgehog signaling pathway_Homo sapiens_hsa043400.08961147
137Fructose and mannose metabolism_Homo sapiens_hsa000510.07513543

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