Rank | Gene Set | Z-score |
---|---|---|
1 | kinetochore organization (GO:0051383) | 5.00525259 |
2 | CENP-A containing nucleosome assembly (GO:0034080) | 4.98521235 |
3 | chromatin remodeling at centromere (GO:0031055) | 4.83222737 |
4 | telomere maintenance via semi-conservative replication (GO:0032201) | 4.82659456 |
5 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.76246452 |
6 | kinetochore assembly (GO:0051382) | 4.56958065 |
7 | DNA strand elongation (GO:0022616) | 4.55043249 |
8 | DNA replication initiation (GO:0006270) | 4.52475724 |
9 | regulation of mitotic spindle organization (GO:0060236) | 4.49624777 |
10 | telomere maintenance via recombination (GO:0000722) | 4.48426011 |
11 | mitotic metaphase plate congression (GO:0007080) | 4.46264212 |
12 | protein localization to kinetochore (GO:0034501) | 4.43868722 |
13 | mitotic sister chromatid cohesion (GO:0007064) | 4.42197201 |
14 | DNA replication checkpoint (GO:0000076) | 4.34095928 |
15 | mitotic recombination (GO:0006312) | 4.32721480 |
16 | establishment of integrated proviral latency (GO:0075713) | 4.27666287 |
17 | DNA replication-independent nucleosome assembly (GO:0006336) | 4.26710855 |
18 | DNA replication-independent nucleosome organization (GO:0034724) | 4.26710855 |
19 | chromosome condensation (GO:0030261) | 4.25500307 |
20 | positive regulation of chromosome segregation (GO:0051984) | 4.20735232 |
21 | attachment of spindle microtubules to kinetochore (GO:0008608) | 4.06416651 |
22 | metaphase plate congression (GO:0051310) | 4.04836059 |
23 | histone exchange (GO:0043486) | 4.02722405 |
24 | telomere maintenance via telomere lengthening (GO:0010833) | 3.95539652 |
25 | protein localization to chromosome, centromeric region (GO:0071459) | 3.95278407 |
26 | meiotic chromosome segregation (GO:0045132) | 3.90582911 |
27 | pore complex assembly (GO:0046931) | 3.90160786 |
28 | establishment of chromosome localization (GO:0051303) | 3.85377415 |
29 | DNA unwinding involved in DNA replication (GO:0006268) | 3.79747322 |
30 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 3.74571299 |
31 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 3.74571299 |
32 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 3.74571299 |
33 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.73200053 |
34 | ribosomal small subunit assembly (GO:0000028) | 3.72776001 |
35 | DNA deamination (GO:0045006) | 3.71183928 |
36 | DNA packaging (GO:0006323) | 3.70552579 |
37 | DNA topological change (GO:0006265) | 3.69136766 |
38 | mitotic sister chromatid segregation (GO:0000070) | 3.57439469 |
39 | maturation of SSU-rRNA (GO:0030490) | 3.55776309 |
40 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 3.53345970 |
41 | regulation of DNA endoreduplication (GO:0032875) | 3.52481394 |
42 | regulation of sister chromatid cohesion (GO:0007063) | 3.52261029 |
43 | mitotic chromosome condensation (GO:0007076) | 3.50966360 |
44 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 3.50811187 |
45 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.49720458 |
46 | spindle checkpoint (GO:0031577) | 3.49509727 |
47 | nucleobase-containing small molecule interconversion (GO:0015949) | 3.48359666 |
48 | proteasome assembly (GO:0043248) | 3.44012385 |
49 | spindle assembly involved in mitosis (GO:0090307) | 3.43432464 |
50 | ribosome assembly (GO:0042255) | 3.43091251 |
51 | regulation of spindle organization (GO:0090224) | 3.40453269 |
52 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 3.39674099 |
53 | mitotic cell cycle (GO:0000278) | 3.37938330 |
54 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 3.37853919 |
55 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 3.37853919 |
56 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 3.37853919 |
57 | negative regulation of sister chromatid segregation (GO:0033046) | 3.37853919 |
58 | DNA replication-dependent nucleosome assembly (GO:0006335) | 3.37723934 |
59 | DNA replication-dependent nucleosome organization (GO:0034723) | 3.37723934 |
60 | nucleobase biosynthetic process (GO:0046112) | 3.37373671 |
61 | non-recombinational repair (GO:0000726) | 3.36386440 |
62 | double-strand break repair via nonhomologous end joining (GO:0006303) | 3.36386440 |
63 | spindle assembly checkpoint (GO:0071173) | 3.35492187 |
64 | negative regulation of chromosome segregation (GO:0051985) | 3.33792579 |
65 | establishment of viral latency (GO:0019043) | 3.30255876 |
66 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.30140946 |
67 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 3.28207397 |
68 | sister chromatid segregation (GO:0000819) | 3.27837078 |
69 | purine nucleobase biosynthetic process (GO:0009113) | 3.27568309 |
70 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 3.26555306 |
71 | mitotic nuclear envelope disassembly (GO:0007077) | 3.26310775 |
72 | DNA conformation change (GO:0071103) | 3.24939310 |
73 | transcription-coupled nucleotide-excision repair (GO:0006283) | 3.22702250 |
74 | mitotic spindle assembly checkpoint (GO:0007094) | 3.21774355 |
75 | microtubule depolymerization (GO:0007019) | 3.20939177 |
76 | telomere maintenance (GO:0000723) | 3.20728791 |
77 | nuclear pore organization (GO:0006999) | 3.20349951 |
78 | deoxyribonucleotide biosynthetic process (GO:0009263) | 3.19642974 |
79 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 3.19357961 |
80 | nuclear envelope organization (GO:0006998) | 3.19149593 |
81 | telomere organization (GO:0032200) | 3.19014737 |
82 | ribosome biogenesis (GO:0042254) | 3.18425425 |
83 | ribosomal large subunit biogenesis (GO:0042273) | 3.18347323 |
84 | DNA duplex unwinding (GO:0032508) | 3.17723785 |
85 | IMP biosynthetic process (GO:0006188) | 3.17068875 |
86 | microtubule cytoskeleton organization involved in mitosis (GO:1902850) | 3.17030337 |
87 | regulation of chromosome segregation (GO:0051983) | 3.16098503 |
88 | protein K6-linked ubiquitination (GO:0085020) | 3.16082844 |
89 | mitotic spindle checkpoint (GO:0071174) | 3.15888192 |
90 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.15799374 |
91 | regulation of sister chromatid segregation (GO:0033045) | 3.12587882 |
92 | regulation of mitotic sister chromatid separation (GO:0010965) | 3.12587882 |
93 | regulation of mitotic sister chromatid segregation (GO:0033047) | 3.12587882 |
94 | mismatch repair (GO:0006298) | 3.11579367 |
95 | formation of translation preinitiation complex (GO:0001731) | 3.10224880 |
96 | DNA ligation (GO:0006266) | 3.10139311 |
97 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.09662382 |
98 | regulation of centriole replication (GO:0046599) | 3.09622774 |
99 | DNA geometric change (GO:0032392) | 3.09383104 |
100 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.08918874 |
101 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.08918287 |
102 | spliceosomal snRNP assembly (GO:0000387) | 3.08813134 |
103 | regulation of centrosome cycle (GO:0046605) | 3.07346061 |
104 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.07272885 |
105 | nuclear pore complex assembly (GO:0051292) | 3.05550138 |
106 | mitotic spindle organization (GO:0007052) | 3.04188629 |
107 | chromosome segregation (GO:0007059) | 3.03931789 |
108 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.03913199 |
109 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 3.03014486 |
110 | mitotic cytokinesis (GO:0000281) | 3.02895689 |
111 | rRNA modification (GO:0000154) | 3.02271676 |
112 | ATP-dependent chromatin remodeling (GO:0043044) | 3.00857898 |
113 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 2.98972375 |
114 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 2.97333843 |
115 | viral mRNA export from host cell nucleus (GO:0046784) | 2.97066639 |
116 | nuclear envelope disassembly (GO:0051081) | 2.95384054 |
117 | membrane disassembly (GO:0030397) | 2.95384054 |
118 | rRNA processing (GO:0006364) | 2.93559832 |
119 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 2.93234658 |
120 | regulation of mitotic spindle checkpoint (GO:1903504) | 2.93234658 |
121 | DNA double-strand break processing (GO:0000729) | 2.92864323 |
122 | chromatin assembly or disassembly (GO:0006333) | 2.92781812 |
123 | G1/S transition of mitotic cell cycle (GO:0000082) | 2.92532149 |
124 | cell cycle G1/S phase transition (GO:0044843) | 2.92532149 |
125 | protein localization to chromosome (GO:0034502) | 2.91510893 |
126 | DNA synthesis involved in DNA repair (GO:0000731) | 2.91146858 |
127 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 2.89247390 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 9.58248423 |
2 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 4.94452357 |
3 | * E2F4_17652178_ChIP-ChIP_JURKAT_Human | 4.46484356 |
4 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.00769422 |
5 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 3.79961006 |
6 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.74722277 |
7 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.14013150 |
8 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.01823995 |
9 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.81099762 |
10 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.80266996 |
11 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.74731384 |
12 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.73439530 |
13 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.67414584 |
14 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.62651992 |
15 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.62273135 |
16 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.50449788 |
17 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.47730129 |
18 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.42567959 |
19 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.37566228 |
20 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.35963892 |
21 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.31383080 |
22 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.28719270 |
23 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 2.27556242 |
24 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.26843023 |
25 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.17711850 |
26 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.14766533 |
27 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 2.09169609 |
28 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.09064847 |
29 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.06852447 |
30 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.06814398 |
31 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.04423671 |
32 | * HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.03852515 |
33 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.89131221 |
34 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.88007725 |
35 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.87616079 |
36 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.87346751 |
37 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.86359883 |
38 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.85409906 |
39 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.80709007 |
40 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.75585753 |
41 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.74967548 |
42 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.72758287 |
43 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.72239068 |
44 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.71769937 |
45 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.65457637 |
46 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.65381935 |
47 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.65294201 |
48 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.63766692 |
49 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.61341906 |
50 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.53241921 |
51 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.52945531 |
52 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.49448973 |
53 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.42628708 |
54 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.42617383 |
55 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.42460353 |
56 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.38955368 |
57 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.38261752 |
58 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.36692374 |
59 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.29262387 |
60 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.27629329 |
61 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.24038505 |
62 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.22109669 |
63 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.21397773 |
64 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.19813716 |
65 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.18537003 |
66 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.18499891 |
67 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.16162262 |
68 | * ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.14901778 |
69 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.13889115 |
70 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.12271188 |
71 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.11585013 |
72 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.11056033 |
73 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.09401629 |
74 | MYC_22102868_ChIP-Seq_BL_Human | 1.08833902 |
75 | * E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.08098389 |
76 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.05868905 |
77 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.05835585 |
78 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.02305217 |
79 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.01029506 |
80 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.00407248 |
81 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.98984958 |
82 | SPI1_23547873_ChIP-Seq_NB4_Human | 0.95756131 |
83 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 0.94685016 |
84 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 0.94535506 |
85 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 0.91701682 |
86 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 0.91329363 |
87 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.91213593 |
88 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.89717170 |
89 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.87136052 |
90 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.83350265 |
91 | TBX5_21415370_ChIP-Seq_HL-1_Mouse | 0.81402985 |
92 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 0.80490609 |
93 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.78698338 |
94 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 0.77928041 |
95 | CHD1_26751641_Chip-Seq_LNCaP_Human | 0.77818979 |
96 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.76778499 |
97 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.76644228 |
98 | * SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.73939756 |
99 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.73458487 |
100 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.72764158 |
101 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.72491030 |
102 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 0.72427299 |
103 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.72409750 |
104 | * CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.72131007 |
105 | TRIM28_19339689_ChIP-ChIP_MESCs_Mouse | 0.72011773 |
106 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.71968577 |
107 | NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 0.70378073 |
108 | EOMES_20176728_ChIP-ChIP_TSCs_Mouse | 0.68511365 |
109 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.68328665 |
110 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.66954958 |
111 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 0.65640923 |
112 | GATA4_21415370_ChIP-Seq_HL-1_Mouse | 0.64943304 |
113 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 0.64178301 |
114 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 0.64178301 |
115 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 0.64178301 |
116 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 0.62046509 |
117 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 0.61982918 |
118 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.61829455 |
119 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.60963140 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003693_abnormal_embryo_hatching | 5.40165692 |
2 | MP0010094_abnormal_chromosome_stability | 4.92198597 |
3 | MP0003111_abnormal_nucleus_morphology | 4.56468832 |
4 | MP0008057_abnormal_DNA_replication | 4.02719101 |
5 | MP0003077_abnormal_cell_cycle | 3.92637202 |
6 | MP0004957_abnormal_blastocyst_morpholog | 3.87977875 |
7 | MP0008058_abnormal_DNA_repair | 3.85890970 |
8 | MP0008007_abnormal_cellular_replicative | 2.91871574 |
9 | MP0002877_abnormal_melanocyte_morpholog | 2.89435352 |
10 | MP0008932_abnormal_embryonic_tissue | 2.69969000 |
11 | MP0008877_abnormal_DNA_methylation | 2.56802107 |
12 | MP0003950_abnormal_plasma_membrane | 2.47606498 |
13 | MP0003786_premature_aging | 2.24338531 |
14 | MP0002396_abnormal_hematopoietic_system | 2.17629572 |
15 | MP0006292_abnormal_olfactory_placode | 2.08702642 |
16 | MP0003705_abnormal_hypodermis_morpholog | 1.96592686 |
17 | MP0003718_maternal_effect | 1.82528520 |
18 | MP0003941_abnormal_skin_development | 1.73511772 |
19 | MP0003123_paternal_imprinting | 1.72869703 |
20 | MP0000350_abnormal_cell_proliferation | 1.72518383 |
21 | MP0003806_abnormal_nucleotide_metabolis | 1.69741180 |
22 | MP0000490_abnormal_crypts_of | 1.66978852 |
23 | MP0005623_abnormal_meninges_morphology | 1.62479596 |
24 | MP0001730_embryonic_growth_arrest | 1.58462289 |
25 | MP0000566_synostosis | 1.56322848 |
26 | MP0010307_abnormal_tumor_latency | 1.45757486 |
27 | MP0002210_abnormal_sex_determination | 1.45513691 |
28 | MP0003315_abnormal_perineum_morphology | 1.43536234 |
29 | MP0004808_abnormal_hematopoietic_stem | 1.41132658 |
30 | MP0000313_abnormal_cell_death | 1.36700889 |
31 | MP0008438_abnormal_cutaneous_collagen | 1.35325780 |
32 | MP0003566_abnormal_cell_adhesion | 1.33685834 |
33 | MP0000358_abnormal_cell_content/ | 1.31721349 |
34 | MP0001188_hyperpigmentation | 1.31250588 |
35 | MP0002132_abnormal_respiratory_system | 1.28578792 |
36 | MP0001672_abnormal_embryogenesis/_devel | 1.26482262 |
37 | MP0005380_embryogenesis_phenotype | 1.26482262 |
38 | MP0002019_abnormal_tumor_incidence | 1.25979630 |
39 | MP0003121_genomic_imprinting | 1.23408574 |
40 | MP0001697_abnormal_embryo_size | 1.21672794 |
41 | MP0002102_abnormal_ear_morphology | 1.19938998 |
42 | MP0003763_abnormal_thymus_physiology | 1.19633025 |
43 | MP0001145_abnormal_male_reproductive | 1.19597505 |
44 | MP0004233_abnormal_muscle_weight | 1.19229316 |
45 | MP0002160_abnormal_reproductive_system | 1.18413254 |
46 | MP0005076_abnormal_cell_differentiation | 1.18411679 |
47 | MP0001929_abnormal_gametogenesis | 1.17029092 |
48 | MP0010234_abnormal_vibrissa_follicle | 1.16536408 |
49 | MP0010352_gastrointestinal_tract_polyps | 1.16076127 |
50 | MP0010030_abnormal_orbit_morphology | 1.15594423 |
51 | MP0003136_yellow_coat_color | 1.15490834 |
52 | MP0002085_abnormal_embryonic_tissue | 1.13901072 |
53 | MP0009697_abnormal_copulation | 1.12923777 |
54 | MP0002095_abnormal_skin_pigmentation | 1.12711289 |
55 | MP0005389_reproductive_system_phenotype | 1.12551510 |
56 | MP0009333_abnormal_splenocyte_physiolog | 1.11943860 |
57 | MP0002080_prenatal_lethality | 1.11817001 |
58 | MP0001293_anophthalmia | 1.10961467 |
59 | MP0005408_hypopigmentation | 1.10005871 |
60 | MP0000015_abnormal_ear_pigmentation | 1.09681873 |
61 | MP0001119_abnormal_female_reproductive | 1.09201119 |
62 | MP0000703_abnormal_thymus_morphology | 1.06858900 |
63 | MP0000653_abnormal_sex_gland | 1.06110459 |
64 | MP0003890_abnormal_embryonic-extraembry | 1.04110013 |
65 | MP0005075_abnormal_melanosome_morpholog | 1.03456567 |
66 | MP0005621_abnormal_cell_physiology | 1.03257157 |
67 | MP0002398_abnormal_bone_marrow | 1.03200477 |
68 | MP0003984_embryonic_growth_retardation | 1.02524195 |
69 | MP0005174_abnormal_tail_pigmentation | 1.01129254 |
70 | MP0001986_abnormal_taste_sensitivity | 1.00986046 |
71 | MP0005501_abnormal_skin_physiology | 1.00669313 |
72 | MP0006035_abnormal_mitochondrial_morpho | 1.00190113 |
73 | MP0003567_abnormal_fetal_cardiomyocyte | 0.99468072 |
74 | MP0002277_abnormal_respiratory_mucosa | 0.98966176 |
75 | MP0002088_abnormal_embryonic_growth/wei | 0.98438413 |
76 | MP0002722_abnormal_immune_system | 0.96161214 |
77 | MP0001835_abnormal_antigen_presentation | 0.95199064 |
78 | MP0001661_extended_life_span | 0.94502349 |
79 | MP0002938_white_spotting | 0.93994891 |
80 | MP0005257_abnormal_intraocular_pressure | 0.93632432 |
81 | MP0003937_abnormal_limbs/digits/tail_de | 0.93284861 |
82 | MP0002084_abnormal_developmental_patter | 0.92944947 |
83 | MP0004185_abnormal_adipocyte_glucose | 0.92637693 |
84 | MP0001853_heart_inflammation | 0.91844365 |
85 | MP0000689_abnormal_spleen_morphology | 0.90787800 |
86 | MP0002060_abnormal_skin_morphology | 0.90420578 |
87 | MP0002086_abnormal_extraembryonic_tissu | 0.89117323 |
88 | MP0009379_abnormal_foot_pigmentation | 0.88732632 |
89 | MP0001919_abnormal_reproductive_system | 0.88361158 |
90 | MP0005395_other_phenotype | 0.87367871 |
91 | MP0004133_heterotaxia | 0.87285407 |
92 | MP0009672_abnormal_birth_weight | 0.86830547 |
93 | MP0004197_abnormal_fetal_growth/weight/ | 0.85793943 |
94 | MP0003186_abnormal_redox_activity | 0.85131064 |
95 | MP0005171_absent_coat_pigmentation | 0.84271393 |
96 | MP0000372_irregular_coat_pigmentation | 0.82795735 |
97 | MP0005397_hematopoietic_system_phenotyp | 0.82677542 |
98 | MP0001545_abnormal_hematopoietic_system | 0.82677542 |
99 | MP0000858_altered_metastatic_potential | 0.80724541 |
100 | MP0002429_abnormal_blood_cell | 0.78675088 |
101 | MP0005671_abnormal_response_to | 0.77753836 |
102 | MP0001243_abnormal_dermal_layer | 0.76715074 |
103 | MP0000049_abnormal_middle_ear | 0.75341141 |
104 | MP0004381_abnormal_hair_follicle | 0.74686248 |
105 | MP0003699_abnormal_female_reproductive | 0.73779955 |
106 | MP0000716_abnormal_immune_system | 0.73494729 |
107 | MP0001286_abnormal_eye_development | 0.73362175 |
108 | MP0002111_abnormal_tail_morphology | 0.71805465 |
109 | MP0003698_abnormal_male_reproductive | 0.71257692 |
110 | MP0002697_abnormal_eye_size | 0.70842863 |
111 | MP0001186_pigmentation_phenotype | 0.70021275 |
112 | MP0003656_abnormal_erythrocyte_physiolo | 0.69955629 |
113 | MP0003943_abnormal_hepatobiliary_system | 0.68214818 |
114 | MP0002148_abnormal_hypersensitivity_rea | 0.67911378 |
115 | MP0001800_abnormal_humoral_immune | 0.67689961 |
116 | MP0002075_abnormal_coat/hair_pigmentati | 0.67208138 |
117 | MP0005023_abnormal_wound_healing | 0.67185845 |
118 | MP0002452_abnormal_antigen_presenting | 0.66770125 |
119 | MP0002420_abnormal_adaptive_immunity | 0.66273702 |
120 | MP0008995_early_reproductive_senescence | 0.66222756 |
121 | MP0001819_abnormal_immune_cell | 0.65649313 |
122 | MP0003221_abnormal_cardiomyocyte_apopto | 0.63977022 |
123 | MP0001881_abnormal_mammary_gland | 0.63616282 |
124 | MP0002177_abnormal_outer_ear | 0.63203908 |
125 | MP0005451_abnormal_body_composition | 0.62319973 |
126 | MP0004272_abnormal_basement_membrane | 0.62185988 |
127 | MP0000428_abnormal_craniofacial_morphol | 0.61655527 |
128 | MP0002269_muscular_atrophy | 0.61412785 |
129 | MP0001348_abnormal_lacrimal_gland | 0.61373729 |
130 | MP0000627_abnormal_mammary_gland | 0.61335194 |
131 | MP0003787_abnormal_imprinting | 0.60616408 |
132 | MP0006036_abnormal_mitochondrial_physio | 0.59912076 |
133 | MP0009785_altered_susceptibility_to | 0.59423733 |
134 | MP0002006_tumorigenesis | 0.59233416 |
135 | MP0000383_abnormal_hair_follicle | 0.58371111 |
136 | MP0002161_abnormal_fertility/fecundity | 0.58236368 |
137 | MP0002092_abnormal_eye_morphology | 0.57893249 |
138 | MP0000537_abnormal_urethra_morphology | 0.57584323 |
139 | MP0000432_abnormal_head_morphology | 0.57207968 |
140 | MP0002723_abnormal_immune_serum | 0.56193189 |
141 | MP0005384_cellular_phenotype | 0.55610364 |
142 | MP0006054_spinal_hemorrhage | 0.55559989 |
143 | MP0002163_abnormal_gland_morphology | 0.55558588 |
144 | MP0000733_abnormal_muscle_development | 0.55536965 |
145 | MP0001216_abnormal_epidermal_layer | 0.54846723 |
146 | MP0003755_abnormal_palate_morphology | 0.54815942 |
147 | MP0001346_abnormal_lacrimal_gland | 0.53500710 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 5.46984228 |
2 | Chromsome breakage (HP:0040012) | 5.46726155 |
3 | Birth length less than 3rd percentile (HP:0003561) | 4.46599396 |
4 | Reticulocytopenia (HP:0001896) | 4.22504493 |
5 | Meckel diverticulum (HP:0002245) | 4.00612953 |
6 | Abnormality of the preputium (HP:0100587) | 4.00341398 |
7 | Abnormality of chromosome stability (HP:0003220) | 3.89350731 |
8 | Abnormality of the ileum (HP:0001549) | 3.78549219 |
9 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 3.71823388 |
10 | Duplicated collecting system (HP:0000081) | 3.53603363 |
11 | Breast hypoplasia (HP:0003187) | 3.39247263 |
12 | Small intestinal stenosis (HP:0012848) | 3.27847707 |
13 | Duodenal stenosis (HP:0100867) | 3.27847707 |
14 | Abnormality of the renal collecting system (HP:0004742) | 3.25398306 |
15 | Patellar aplasia (HP:0006443) | 3.08771277 |
16 | Ectopic kidney (HP:0000086) | 2.97637543 |
17 | Myelodysplasia (HP:0002863) | 2.97143694 |
18 | Absent thumb (HP:0009777) | 2.95677995 |
19 | Absent radius (HP:0003974) | 2.93589493 |
20 | Abnormal lung lobation (HP:0002101) | 2.92244795 |
21 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.88410629 |
22 | Clubbing of toes (HP:0100760) | 2.85801397 |
23 | Bone marrow hypocellularity (HP:0005528) | 2.84409973 |
24 | Impulsivity (HP:0100710) | 2.84252321 |
25 | Abnormal number of erythroid precursors (HP:0012131) | 2.80184733 |
26 | Aplastic anemia (HP:0001915) | 2.74997532 |
27 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.74159851 |
28 | Absent forearm bone (HP:0003953) | 2.73830805 |
29 | Aplasia involving forearm bones (HP:0009822) | 2.73830805 |
30 | Oral leukoplakia (HP:0002745) | 2.72825394 |
31 | Selective tooth agenesis (HP:0001592) | 2.72394707 |
32 | Abnormality of the duodenum (HP:0002246) | 2.68473115 |
33 | Colon cancer (HP:0003003) | 2.68137108 |
34 | Supernumerary spleens (HP:0009799) | 2.60592233 |
35 | Triphalangeal thumb (HP:0001199) | 2.59610558 |
36 | Entropion (HP:0000621) | 2.59541151 |
37 | Sloping forehead (HP:0000340) | 2.58976007 |
38 | Poikiloderma (HP:0001029) | 2.56931048 |
39 | Cafe-au-lait spot (HP:0000957) | 2.54787971 |
40 | Abnormality of DNA repair (HP:0003254) | 2.54779768 |
41 | Premature rupture of membranes (HP:0001788) | 2.54579834 |
42 | Ankle contracture (HP:0006466) | 2.52399417 |
43 | Carpal bone hypoplasia (HP:0001498) | 2.48167458 |
44 | 11 pairs of ribs (HP:0000878) | 2.46749741 |
45 | Abnormality of the carotid arteries (HP:0005344) | 2.46676690 |
46 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.44096687 |
47 | Premature graying of hair (HP:0002216) | 2.43761327 |
48 | Medulloblastoma (HP:0002885) | 2.43124173 |
49 | Proximal placement of thumb (HP:0009623) | 2.41137757 |
50 | Deviation of the thumb (HP:0009603) | 2.40672261 |
51 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.40139935 |
52 | Rough bone trabeculation (HP:0100670) | 2.38560134 |
53 | Abnormality of glycolysis (HP:0004366) | 2.37422805 |
54 | Horseshoe kidney (HP:0000085) | 2.33307591 |
55 | Agnosia (HP:0010524) | 2.29480591 |
56 | Overlapping toe (HP:0001845) | 2.28161394 |
57 | Abnormality of the umbilical cord (HP:0010881) | 2.28037456 |
58 | Embryonal renal neoplasm (HP:0011794) | 2.27672239 |
59 | Pallor (HP:0000980) | 2.27617790 |
60 | Type I transferrin isoform profile (HP:0003642) | 2.26243462 |
61 | Cortical dysplasia (HP:0002539) | 2.25997347 |
62 | Short thumb (HP:0009778) | 2.23658272 |
63 | Ependymoma (HP:0002888) | 2.21414206 |
64 | Tracheoesophageal fistula (HP:0002575) | 2.21172928 |
65 | Progressive muscle weakness (HP:0003323) | 2.15600163 |
66 | Cleft eyelid (HP:0000625) | 2.13225087 |
67 | Cutaneous melanoma (HP:0012056) | 2.12584854 |
68 | Abnormality of the fetal cardiovascular system (HP:0010948) | 2.11585462 |
69 | Abnormal umbilical cord blood vessels (HP:0011403) | 2.11585462 |
70 | Single umbilical artery (HP:0001195) | 2.11585462 |
71 | Secondary amenorrhea (HP:0000869) | 2.10068055 |
72 | Increased serum pyruvate (HP:0003542) | 2.09205153 |
73 | Degeneration of anterior horn cells (HP:0002398) | 2.07586782 |
74 | Abnormality of the anterior horn cell (HP:0006802) | 2.07586782 |
75 | Deep philtrum (HP:0002002) | 2.07143622 |
76 | Choanal atresia (HP:0000453) | 2.07039622 |
77 | Macrocytic anemia (HP:0001972) | 2.04371649 |
78 | Pancytopenia (HP:0001876) | 2.03622096 |
79 | Type 2 muscle fiber atrophy (HP:0003554) | 2.02550773 |
80 | Microglossia (HP:0000171) | 2.01011473 |
81 | Abnormal number of incisors (HP:0011064) | 2.00039098 |
82 | Trismus (HP:0000211) | 1.98492744 |
83 | Neoplasm of the pancreas (HP:0002894) | 1.97618492 |
84 | Lymphoma (HP:0002665) | 1.93720607 |
85 | Multiple enchondromatosis (HP:0005701) | 1.93662476 |
86 | Abnormal trabecular bone morphology (HP:0100671) | 1.92398370 |
87 | Abnormal spermatogenesis (HP:0008669) | 1.92144339 |
88 | Aplasia/Hypoplasia of the earlobes (HP:0009906) | 1.88122751 |
89 | Abnormal auditory evoked potentials (HP:0006958) | 1.87594293 |
90 | Ureteral duplication (HP:0000073) | 1.87227983 |
91 | Microretrognathia (HP:0000308) | 1.86765481 |
92 | Muscle fiber atrophy (HP:0100295) | 1.86258342 |
93 | Facial hemangioma (HP:0000329) | 1.86053041 |
94 | Abnormality of chromosome segregation (HP:0002916) | 1.86010008 |
95 | Reduced subcutaneous adipose tissue (HP:0003758) | 1.85151377 |
96 | Cellular immunodeficiency (HP:0005374) | 1.83359629 |
97 | Optic nerve coloboma (HP:0000588) | 1.82957515 |
98 | Orthostatic hypotension (HP:0001278) | 1.82900769 |
99 | Duplication of thumb phalanx (HP:0009942) | 1.82486187 |
100 | Facial cleft (HP:0002006) | 1.82299152 |
101 | Hypoplastic pelvis (HP:0008839) | 1.81845197 |
102 | Increased nuchal translucency (HP:0010880) | 1.81797657 |
103 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 1.80712874 |
104 | Abnormal gallbladder physiology (HP:0012438) | 1.78704815 |
105 | Cholecystitis (HP:0001082) | 1.78704815 |
106 | Prominent nose (HP:0000448) | 1.77672464 |
107 | High pitched voice (HP:0001620) | 1.77619114 |
108 | Astrocytoma (HP:0009592) | 1.75859749 |
109 | Abnormality of the astrocytes (HP:0100707) | 1.75859749 |
110 | Glioma (HP:0009733) | 1.75144443 |
111 | Abnormality of pyrimidine metabolism (HP:0004353) | 1.74602304 |
112 | Embryonal neoplasm (HP:0002898) | 1.74492388 |
113 | Insomnia (HP:0100785) | 1.73557909 |
114 | Hyperacusis (HP:0010780) | 1.73451461 |
115 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 1.72371975 |
116 | Hypoplasia of the radius (HP:0002984) | 1.72350621 |
117 | Capillary hemangiomas (HP:0005306) | 1.71166671 |
118 | IgM deficiency (HP:0002850) | 1.70991470 |
119 | Volvulus (HP:0002580) | 1.70816440 |
120 | Neoplasm of the colon (HP:0100273) | 1.70183535 |
121 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.69343925 |
122 | Abnormalities of placenta or umbilical cord (HP:0001194) | 1.68760861 |
123 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.68484514 |
124 | Osteolytic defects of the hand bones (HP:0009699) | 1.68484514 |
125 | Sparse eyelashes (HP:0000653) | 1.68119747 |
126 | Microvesicular hepatic steatosis (HP:0001414) | 1.68109842 |
127 | Leukopenia (HP:0001882) | 1.67679313 |
128 | Elbow flexion contracture (HP:0002987) | 1.67514490 |
129 | Abnormality of the labia minora (HP:0012880) | 1.67196621 |
130 | Pancreatic cysts (HP:0001737) | 1.66389791 |
131 | Shoulder girdle muscle weakness (HP:0003547) | 1.66307242 |
132 | Upper limb muscle weakness (HP:0003484) | 1.65446170 |
133 | Small epiphyses (HP:0010585) | 1.64680415 |
134 | Asplenia (HP:0001746) | 1.64366954 |
135 | Hypergonadotropic hypogonadism (HP:0000815) | 1.63766071 |
136 | Atresia of the external auditory canal (HP:0000413) | 1.63651914 |
137 | Cerebral hypomyelination (HP:0006808) | 1.63386187 |
138 | Progressive external ophthalmoplegia (HP:0000590) | 1.63112297 |
139 | Arteriovenous malformation (HP:0100026) | 1.61396859 |
140 | Preaxial hand polydactyly (HP:0001177) | 1.59340802 |
141 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 1.56568068 |
142 | Granulocytopenia (HP:0001913) | 1.56189051 |
143 | Amaurosis fugax (HP:0100576) | 1.55943855 |
144 | True hermaphroditism (HP:0010459) | 1.54115422 |
145 | Rhabdomyosarcoma (HP:0002859) | 1.53764640 |
146 | Squamous cell carcinoma (HP:0002860) | 1.53741871 |
147 | Hypopigmented skin patches (HP:0001053) | 1.52520371 |
148 | Reduced antithrombin III activity (HP:0001976) | 1.52170611 |
149 | Oligohydramnios (HP:0001562) | 1.52110488 |
150 | Pancreatic fibrosis (HP:0100732) | 1.52014207 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BUB1 | 4.89179478 |
2 | WEE1 | 4.10954547 |
3 | CDC7 | 3.67782293 |
4 | PLK4 | 3.52556072 |
5 | STK16 | 3.20299158 |
6 | SRPK1 | 2.91432827 |
7 | TTK | 2.66310671 |
8 | EIF2AK1 | 2.65087241 |
9 | ZAK | 2.60142213 |
10 | BRSK2 | 2.43443858 |
11 | NEK2 | 2.29976418 |
12 | MKNK1 | 2.19692572 |
13 | PLK1 | 2.10780743 |
14 | VRK1 | 2.08479170 |
15 | ACVR1B | 1.92085967 |
16 | EIF2AK3 | 1.88726061 |
17 | CCNB1 | 1.88619571 |
18 | PLK3 | 1.85369752 |
19 | VRK2 | 1.85364464 |
20 | IRAK3 | 1.82273524 |
21 | MKNK2 | 1.78147879 |
22 | AURKB | 1.74004793 |
23 | TSSK6 | 1.72239308 |
24 | ATR | 1.71080009 |
25 | MST1R | 1.70867047 |
26 | CHEK2 | 1.56947903 |
27 | IRAK4 | 1.56393148 |
28 | SCYL2 | 1.55646427 |
29 | NEK1 | 1.54478260 |
30 | EIF2AK2 | 1.54029162 |
31 | PBK | 1.45604639 |
32 | DYRK3 | 1.43299948 |
33 | CDK7 | 1.43252550 |
34 | BRSK1 | 1.42793770 |
35 | TLK1 | 1.40812903 |
36 | NME2 | 1.33208998 |
37 | STK4 | 1.32702776 |
38 | PASK | 1.32187827 |
39 | SMG1 | 1.23638590 |
40 | TESK2 | 1.22166803 |
41 | TAF1 | 1.19634223 |
42 | RPS6KA4 | 1.18815530 |
43 | AURKA | 1.16329875 |
44 | EPHA2 | 1.13977784 |
45 | ERBB4 | 1.10762719 |
46 | MET | 1.10685158 |
47 | RPS6KB2 | 1.01140920 |
48 | TRIM28 | 1.00176983 |
49 | CHEK1 | 1.00156649 |
50 | CDK8 | 0.99048633 |
51 | STK10 | 0.98734429 |
52 | MAP3K8 | 0.91881814 |
53 | CLK1 | 0.86760460 |
54 | CDK4 | 0.85867464 |
55 | ATM | 0.81826425 |
56 | TXK | 0.78719359 |
57 | BRD4 | 0.78616641 |
58 | YES1 | 0.77903558 |
59 | BRAF | 0.77708344 |
60 | PDK2 | 0.77435059 |
61 | LATS2 | 0.77403817 |
62 | TGFBR1 | 0.76173617 |
63 | BLK | 0.73243358 |
64 | TEC | 0.72507035 |
65 | PIM1 | 0.72464750 |
66 | CSNK2A1 | 0.68037535 |
67 | LATS1 | 0.65860164 |
68 | MST4 | 0.65422953 |
69 | ARAF | 0.65302233 |
70 | CDK2 | 0.65124630 |
71 | RPS6KA5 | 0.63388368 |
72 | LIMK1 | 0.61913815 |
73 | NUAK1 | 0.60493155 |
74 | PTK2 | 0.59551569 |
75 | CDK1 | 0.58579537 |
76 | MELK | 0.58111157 |
77 | PAK4 | 0.57410837 |
78 | MAP3K10 | 0.57064965 |
79 | CSNK2A2 | 0.53905411 |
80 | PIM2 | 0.51166481 |
81 | ICK | 0.50929855 |
82 | CDK12 | 0.50892721 |
83 | PRKCI | 0.50088370 |
84 | TESK1 | 0.49931193 |
85 | MOS | 0.49799396 |
86 | PNCK | 0.49030073 |
87 | PAK2 | 0.49000363 |
88 | KDR | 0.47932537 |
89 | CDK9 | 0.46817619 |
90 | AKT2 | 0.46493485 |
91 | EEF2K | 0.46485408 |
92 | BTK | 0.46316664 |
93 | IRAK1 | 0.45891221 |
94 | AKT3 | 0.45453686 |
95 | MAP3K14 | 0.45406466 |
96 | ERBB3 | 0.44138530 |
97 | CDK6 | 0.44132941 |
98 | TTN | 0.44067054 |
99 | MAP4K1 | 0.43857729 |
100 | MAPK11 | 0.43222895 |
101 | PAK1 | 0.42918993 |
102 | STK3 | 0.42743121 |
103 | CDK18 | 0.42609899 |
104 | BMPR1B | 0.41403293 |
105 | STK38L | 0.40631852 |
106 | NEK6 | 0.40316416 |
107 | CDK15 | 0.40310350 |
108 | CDK11A | 0.39781449 |
109 | ALK | 0.39347642 |
110 | MARK3 | 0.37847494 |
111 | IKBKB | 0.36431513 |
112 | RAF1 | 0.36429612 |
113 | CDK14 | 0.35330503 |
114 | NEK9 | 0.35032304 |
115 | LYN | 0.34521580 |
116 | DYRK2 | 0.33247212 |
117 | ADRBK2 | 0.32899431 |
118 | CDK3 | 0.30690201 |
119 | IRAK2 | 0.29496707 |
120 | PDGFRA | 0.27655300 |
121 | CHUK | 0.25100479 |
122 | PRKDC | 0.24248372 |
123 | KIT | 0.24005532 |
124 | DAPK1 | 0.23934990 |
125 | PLK2 | 0.23579160 |
126 | ILK | 0.23234245 |
127 | MTOR | 0.22597781 |
128 | NLK | 0.22542309 |
129 | KSR1 | 0.20169393 |
130 | SIK3 | 0.18324464 |
131 | MAPK14 | 0.18139457 |
132 | JAK3 | 0.17110790 |
133 | NME1 | 0.16149463 |
134 | TAOK2 | 0.15904701 |
135 | AKT1 | 0.15373074 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DNA replication_Homo sapiens_hsa03030 | 5.03768150 |
2 | Mismatch repair_Homo sapiens_hsa03430 | 4.36137845 |
3 | Homologous recombination_Homo sapiens_hsa03440 | 3.43318413 |
4 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.31613420 |
5 | Proteasome_Homo sapiens_hsa03050 | 3.31234598 |
6 | RNA polymerase_Homo sapiens_hsa03020 | 3.17905943 |
7 | Spliceosome_Homo sapiens_hsa03040 | 3.10850488 |
8 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 3.09120180 |
9 | Base excision repair_Homo sapiens_hsa03410 | 3.07438196 |
10 | Ribosome_Homo sapiens_hsa03010 | 3.05710663 |
11 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.95746386 |
12 | Cell cycle_Homo sapiens_hsa04110 | 2.76735433 |
13 | RNA transport_Homo sapiens_hsa03013 | 2.69160619 |
14 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.58610373 |
15 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.37838012 |
16 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.24187103 |
17 | Basal transcription factors_Homo sapiens_hsa03022 | 2.20143889 |
18 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 2.09493736 |
19 | RNA degradation_Homo sapiens_hsa03018 | 1.92864272 |
20 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.70456128 |
21 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.70302741 |
22 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.55863197 |
23 | Purine metabolism_Homo sapiens_hsa00230 | 1.49941057 |
24 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.45151288 |
25 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.39249893 |
26 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.29299503 |
27 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.27224144 |
28 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.17230576 |
29 | Carbon metabolism_Homo sapiens_hsa01200 | 1.03589071 |
30 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.02743580 |
31 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.02504467 |
32 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.01683858 |
33 | Protein export_Homo sapiens_hsa03060 | 0.99189745 |
34 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.98056343 |
35 | Sulfur relay system_Homo sapiens_hsa04122 | 0.95272887 |
36 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.87052770 |
37 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.84548132 |
38 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.84048178 |
39 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.80969062 |
40 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.80685331 |
41 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.80136732 |
42 | Bladder cancer_Homo sapiens_hsa05219 | 0.77223161 |
43 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.75850133 |
44 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.74348713 |
45 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.73774265 |
46 | Huntingtons disease_Homo sapiens_hsa05016 | 0.72841094 |
47 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.71138396 |
48 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.70800741 |
49 | HTLV-I infection_Homo sapiens_hsa05166 | 0.70078202 |
50 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.69898894 |
51 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.67460190 |
52 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.66717168 |
53 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.66477950 |
54 | Legionellosis_Homo sapiens_hsa05134 | 0.61886267 |
55 | Measles_Homo sapiens_hsa05162 | 0.61653978 |
56 | Allograft rejection_Homo sapiens_hsa05330 | 0.58380349 |
57 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.57633372 |
58 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.56627772 |
59 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.55325664 |
60 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.55122694 |
61 | Lysine degradation_Homo sapiens_hsa00310 | 0.55085921 |
62 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.54698789 |
63 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.54155416 |
64 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.52990792 |
65 | Asthma_Homo sapiens_hsa05310 | 0.52957580 |
66 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.52909729 |
67 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.52376567 |
68 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.52211930 |
69 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.51432508 |
70 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.51329775 |
71 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.51303258 |
72 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.49907091 |
73 | Parkinsons disease_Homo sapiens_hsa05012 | 0.49348716 |
74 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.49231909 |
75 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.47673753 |
76 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.47509305 |
77 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.46183301 |
78 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.46083974 |
79 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.45811336 |
80 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.45366451 |
81 | Adherens junction_Homo sapiens_hsa04520 | 0.44969864 |
82 | Prostate cancer_Homo sapiens_hsa05215 | 0.44736294 |
83 | Apoptosis_Homo sapiens_hsa04210 | 0.43266645 |
84 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.42324590 |
85 | Melanoma_Homo sapiens_hsa05218 | 0.42034972 |
86 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.41899080 |
87 | Galactose metabolism_Homo sapiens_hsa00052 | 0.40577062 |
88 | Alcoholism_Homo sapiens_hsa05034 | 0.40098751 |
89 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.37851985 |
90 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.36779627 |
91 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.35448275 |
92 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.35088878 |
93 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.34981587 |
94 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.34122788 |
95 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.33344664 |
96 | Influenza A_Homo sapiens_hsa05164 | 0.31709420 |
97 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.31447269 |
98 | Hepatitis B_Homo sapiens_hsa05161 | 0.31341751 |
99 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.30449364 |
100 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.29312078 |
101 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.28423107 |
102 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.28154698 |
103 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.27735648 |
104 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.27656813 |
105 | Shigellosis_Homo sapiens_hsa05131 | 0.26207408 |
106 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.26027384 |
107 | Metabolic pathways_Homo sapiens_hsa01100 | 0.23733448 |
108 | Other glycan degradation_Homo sapiens_hsa00511 | 0.23431201 |
109 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.23127316 |
110 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.21386210 |
111 | Pathways in cancer_Homo sapiens_hsa05200 | 0.19638352 |
112 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.19261088 |
113 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.19102119 |
114 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.18950324 |
115 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.18235491 |
116 | Leishmaniasis_Homo sapiens_hsa05140 | 0.18146472 |
117 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.16308655 |
118 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.15668039 |
119 | Thyroid cancer_Homo sapiens_hsa05216 | 0.15538196 |
120 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.15171772 |
121 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.15095745 |
122 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.14357980 |
123 | Focal adhesion_Homo sapiens_hsa04510 | 0.13676073 |
124 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.13307753 |
125 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.13178670 |
126 | Viral myocarditis_Homo sapiens_hsa05416 | 0.12928729 |
127 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.12881762 |
128 | Colorectal cancer_Homo sapiens_hsa05210 | 0.12503439 |
129 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.12040686 |
130 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.12035439 |
131 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.11654511 |
132 | Phototransduction_Homo sapiens_hsa04744 | 0.11498564 |
133 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.11279789 |
134 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.10812942 |
135 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.09901652 |
136 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.08961147 |
137 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.07513543 |