SHD

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1enteric nervous system development (GO:0048484)7.16145405
2response to pheromone (GO:0019236)5.98353589
3pyrimidine nucleobase catabolic process (GO:0006208)5.90902180
4neuron cell-cell adhesion (GO:0007158)5.89066974
5regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.28252526
6behavioral response to nicotine (GO:0035095)5.13259246
7sympathetic nervous system development (GO:0048485)5.12078053
8vocalization behavior (GO:0071625)5.08880798
9neuron recognition (GO:0008038)4.95412187
10axonal fasciculation (GO:0007413)4.91824187
11protein localization to synapse (GO:0035418)4.68352368
12cardiac chamber formation (GO:0003207)4.63856595
13nucleobase catabolic process (GO:0046113)4.54096861
14cardiac ventricle formation (GO:0003211)4.53731104
15dendritic spine morphogenesis (GO:0060997)4.49693990
16regulation of short-term neuronal synaptic plasticity (GO:0048172)4.48403856
17cell migration in hindbrain (GO:0021535)4.45525832
18regulation of glutamate receptor signaling pathway (GO:1900449)4.45102956
19layer formation in cerebral cortex (GO:0021819)4.38418659
20synaptic vesicle exocytosis (GO:0016079)4.30102613
21positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.19765032
22response to inactivity (GO:0014854)4.16023728
23positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.10446810
24positive regulation of synapse assembly (GO:0051965)4.07554256
25negative regulation of microtubule polymerization (GO:0031115)4.07090871
26locomotory exploration behavior (GO:0035641)4.06939485
27presynaptic membrane organization (GO:0097090)4.06279038
28mechanosensory behavior (GO:0007638)3.97730421
29postsynaptic membrane organization (GO:0001941)3.97064379
30endocardial cushion morphogenesis (GO:0003203)3.90461491
31neuromuscular synaptic transmission (GO:0007274)3.84451178
32synaptic vesicle maturation (GO:0016188)3.82074650
33exploration behavior (GO:0035640)3.81048638
34presynaptic membrane assembly (GO:0097105)3.80546423
35regulation of synaptic vesicle exocytosis (GO:2000300)3.78674544
36ionotropic glutamate receptor signaling pathway (GO:0035235)3.74999323
37regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.67874082
38dendrite morphogenesis (GO:0048813)3.65472975
39glutamate secretion (GO:0014047)3.61767450
40cerebellar Purkinje cell differentiation (GO:0021702)3.60014231
41negative regulation of cytosolic calcium ion concentration (GO:0051481)3.58644899
42synaptic transmission, cholinergic (GO:0007271)3.56422374
43neurotransmitter secretion (GO:0007269)3.56235167
44central nervous system projection neuron axonogenesis (GO:0021952)3.53390797
45muscle cell fate commitment (GO:0042693)3.50361867
46regulation of synapse structural plasticity (GO:0051823)3.49793664
47regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.48615389
48peripheral nervous system neuron development (GO:0048935)3.47347758
49glutamate receptor signaling pathway (GO:0007215)3.45716787
50neuronal action potential propagation (GO:0019227)3.43654715
51regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.42681923
52transmission of nerve impulse (GO:0019226)3.38721919
53gamma-aminobutyric acid transport (GO:0015812)3.37910943
54regulation of respiratory system process (GO:0044065)3.35070006
55synaptic transmission, glutamatergic (GO:0035249)3.31961355
56regulation of secondary heart field cardioblast proliferation (GO:0003266)3.31665232
57regulation of cardioblast proliferation (GO:0003264)3.31665232
58ganglion development (GO:0061548)3.29583777
59regulation of synapse assembly (GO:0051963)3.29549808
60cell migration involved in heart development (GO:0060973)3.26067569
61positive regulation of synapse maturation (GO:0090129)3.25765934
62regulation of synaptic vesicle transport (GO:1902803)3.25617597
63hippocampus development (GO:0021766)3.25020166
64response to auditory stimulus (GO:0010996)3.24853278
65auditory behavior (GO:0031223)3.24614855
66regulation of neuronal synaptic plasticity (GO:0048168)3.21143410
67cartilage morphogenesis (GO:0060536)3.19939010
68negative regulation of cardiac muscle cell apoptotic process (GO:0010667)3.19813448
69positive regulation of synaptic transmission, GABAergic (GO:0032230)3.16583946
70regulation of respiratory gaseous exchange (GO:0043576)3.16558614
71chaperone-mediated protein transport (GO:0072321)3.15566537
72neuronal ion channel clustering (GO:0045161)3.11377762
73dermatan sulfate biosynthetic process (GO:0030208)3.10780862
74neurotransmitter-gated ion channel clustering (GO:0072578)3.07571419
75synapse assembly (GO:0007416)3.07213493
76forebrain neuron differentiation (GO:0021879)3.07030135
77neuron-neuron synaptic transmission (GO:0007270)3.06335245
78establishment of mitochondrion localization (GO:0051654)3.05777993
79membrane hyperpolarization (GO:0060081)3.02889239
80G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.02872618
81mesenchyme morphogenesis (GO:0072132)3.02779865
82regulation of synapse organization (GO:0050807)3.00741158
83membrane assembly (GO:0071709)2.97844039
84neurotransmitter transport (GO:0006836)2.96556110
85positive regulation of membrane potential (GO:0045838)2.95879977
86dopaminergic neuron differentiation (GO:0071542)2.95679319
87positive regulation of myotube differentiation (GO:0010831)2.95185487
88synaptic vesicle endocytosis (GO:0048488)2.94759831
89regulation of synaptic transmission, glutamatergic (GO:0051966)2.94314494
90synaptic vesicle docking involved in exocytosis (GO:0016081)2.93479917
91mating behavior (GO:0007617)2.93205455
92negative regulation of axon extension (GO:0030517)2.92271336
93positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.91301017
94cell differentiation in hindbrain (GO:0021533)2.91170816
95cerebellar granule cell differentiation (GO:0021707)2.90553840
96axon ensheathment in central nervous system (GO:0032291)2.90062437
97central nervous system myelination (GO:0022010)2.90062437
98regulation of long-term neuronal synaptic plasticity (GO:0048169)2.89753234
99prepulse inhibition (GO:0060134)2.89697935
100dendrite development (GO:0016358)2.89345771
101membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.87501405
102adult walking behavior (GO:0007628)2.86978521
103synapse organization (GO:0050808)2.86960268
104tongue development (GO:0043586)2.85066124
105axon extension (GO:0048675)2.84294945
106negative regulation of synaptic transmission, GABAergic (GO:0032229)2.82770358
107gonadal mesoderm development (GO:0007506)2.82730510
108eye photoreceptor cell differentiation (GO:0001754)2.82402535
109photoreceptor cell differentiation (GO:0046530)2.82402535
110cell communication by electrical coupling (GO:0010644)2.81887169
111cerebellum development (GO:0021549)2.81794628
112regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.81399073
113regulation of excitatory postsynaptic membrane potential (GO:0060079)2.81212227
114behavioral response to ethanol (GO:0048149)2.81169268
115neuromuscular process controlling posture (GO:0050884)2.79564520
116regulation of postsynaptic membrane potential (GO:0060078)2.79281330
117paraxial mesoderm development (GO:0048339)2.79137298
118positive regulation of dendritic spine development (GO:0060999)2.78881885
119neuron migration (GO:0001764)2.78834824
120negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.77416155
121regulation of neurotransmitter secretion (GO:0046928)2.77280109
122dermatan sulfate metabolic process (GO:0030205)2.76882285
123mitochondrial fragmentation involved in apoptotic process (GO:0043653)2.76406488
124regulation of dendritic spine morphogenesis (GO:0061001)2.74752566
125regulation of synapse maturation (GO:0090128)2.74039450
126gamma-aminobutyric acid signaling pathway (GO:0007214)2.73103121
127learning (GO:0007612)2.72351382
128regulation of neurotransmitter levels (GO:0001505)2.71969258
129L-amino acid import (GO:0043092)2.71391269
130innervation (GO:0060384)2.69905419
131proline transport (GO:0015824)2.69895860
132cAMP-mediated signaling (GO:0019933)2.69460056
133potassium ion homeostasis (GO:0055075)2.69415677
134establishment of nucleus localization (GO:0040023)2.68846154
135calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.61008740
136negative regulation of dendrite development (GO:2000171)2.60170948
137response to stimulus involved in regulation of muscle adaptation (GO:0014874)2.58977862
138mitochondrion transport along microtubule (GO:0047497)2.57388332
139establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.57388332
140negative regulation of axonogenesis (GO:0050771)2.56104905
141positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.54550424
142myotube differentiation (GO:0014902)2.53707840
143spinal cord motor neuron differentiation (GO:0021522)2.52622355
144regulation of cell maturation (GO:1903429)2.52513351
145neural crest cell migration (GO:0001755)2.50538812
146neuronal stem cell maintenance (GO:0097150)2.49610425
147negative regulation of dendrite morphogenesis (GO:0050774)2.47086311
148central nervous system neuron axonogenesis (GO:0021955)2.44849881
149positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.43617565
150positive regulation of skeletal muscle tissue development (GO:0048643)2.39163431
151cerebellar Purkinje cell layer development (GO:0021680)2.38370334
152regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)2.37510560
153regulation of NFAT protein import into nucleus (GO:0051532)2.35612196
154cell differentiation in spinal cord (GO:0021515)2.35318776
155regulation of membrane repolarization (GO:0060306)2.35166277

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.11337719
2JARID2_20064375_ChIP-Seq_MESCs_Mouse3.27446390
3EZH2_27304074_Chip-Seq_ESCs_Mouse3.22021929
4GBX2_23144817_ChIP-Seq_PC3_Human3.19288135
5SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.17082425
6SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.07863006
7JARID2_20075857_ChIP-Seq_MESCs_Mouse2.88675970
8EZH2_18974828_ChIP-Seq_MESCs_Mouse2.88124255
9RNF2_18974828_ChIP-Seq_MESCs_Mouse2.88124255
10NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.86965134
11SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.85055907
12EED_16625203_ChIP-ChIP_MESCs_Mouse2.81845755
13SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.67230825
14SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.64950823
15EZH2_27294783_Chip-Seq_ESCs_Mouse2.64066523
16REST_21632747_ChIP-Seq_MESCs_Mouse2.59961675
17* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.58641461
18CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.49399555
19RNF2_27304074_Chip-Seq_ESCs_Mouse2.39487063
20* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.37989278
21MTF2_20144788_ChIP-Seq_MESCs_Mouse2.36970590
22CBX2_27304074_Chip-Seq_ESCs_Mouse2.29945035
23GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.28676400
24REST_18959480_ChIP-ChIP_MESCs_Mouse2.18991491
25PHC1_16625203_ChIP-ChIP_MESCs_Mouse2.16427274
26BMI1_23680149_ChIP-Seq_NPCS_Mouse2.07820135
27AR_21572438_ChIP-Seq_LNCaP_Human2.00947120
28ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.99153253
29TAF15_26573619_Chip-Seq_HEK293_Human1.95543524
30CTBP2_25329375_ChIP-Seq_LNCAP_Human1.87250106
31DROSHA_22980978_ChIP-Seq_HELA_Human1.87105744
32RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.81380266
33RNF2_27304074_Chip-Seq_NSC_Mouse1.80998198
34RBPJ_22232070_ChIP-Seq_NCS_Mouse1.80553187
35ZNF274_21170338_ChIP-Seq_K562_Hela1.79868763
36RARB_27405468_Chip-Seq_BRAIN_Mouse1.74998289
37CTBP1_25329375_ChIP-Seq_LNCAP_Human1.69947381
38RING1B_27294783_Chip-Seq_ESCs_Mouse1.66327036
39IKZF1_21737484_ChIP-ChIP_HCT116_Human1.65598077
40ZFP57_27257070_Chip-Seq_ESCs_Mouse1.60305623
41RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.57290612
42EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.56064808
43PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.55903871
44MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.52452821
45ERG_21242973_ChIP-ChIP_JURKAT_Human1.51174425
46RING1B_27294783_Chip-Seq_NPCs_Mouse1.46484069
47HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.39931987
48IGF1R_20145208_ChIP-Seq_DFB_Human1.39875810
49P300_19829295_ChIP-Seq_ESCs_Human1.33331819
50OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.29077803
51TOP2B_26459242_ChIP-Seq_MCF-7_Human1.26525551
52GATA1_26923725_Chip-Seq_HPCs_Mouse1.24465939
53TP53_20018659_ChIP-ChIP_R1E_Mouse1.24336287
54GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.23987840
55ZFP281_18757296_ChIP-ChIP_E14_Mouse1.23701927
56POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.23337614
57TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.23337614
58SMAD4_21799915_ChIP-Seq_A2780_Human1.22051691
59CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.16004330
60P53_22127205_ChIP-Seq_FIBROBLAST_Human1.15424240
61* SMAD3_21741376_ChIP-Seq_EPCs_Human1.15153402
62SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.15043869
63CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.13673069
64ZFP281_27345836_Chip-Seq_ESCs_Mouse1.13442897
65RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.13235890
66POU5F1_16153702_ChIP-ChIP_HESCs_Human1.12118205
67SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.12079247
68OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.09530020
69TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.09312956
70SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.08103021
71DNAJC2_21179169_ChIP-ChIP_NT2_Human1.06916953
72VDR_22108803_ChIP-Seq_LS180_Human1.06808780
73HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.06759406
74ISL1_27105846_Chip-Seq_CPCs_Mouse1.06757883
75SOX2_21211035_ChIP-Seq_LN229_Gbm1.05884459
76NR3C1_23031785_ChIP-Seq_PC12_Mouse1.04770969
77CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.03081216
78SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.02849943
79EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.02722831
80AR_25329375_ChIP-Seq_VCAP_Human1.01772476
81PIAS1_25552417_ChIP-Seq_VCAP_Human1.00683154
82TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.98156125
83STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.97201220
84TRIM28_21343339_ChIP-Seq_HEK293_Human0.96334562
85TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.94764773
86LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.92895168
87UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.91929665
88AR_19668381_ChIP-Seq_PC3_Human0.91542080
89TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.90536712
90FUS_26573619_Chip-Seq_HEK293_Human0.90027116
91CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.89919092
92TP63_19390658_ChIP-ChIP_HaCaT_Human0.89814295
93TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.89712473
94RUNX2_22187159_ChIP-Seq_PCA_Human0.89702431
95* SMAD3_21741376_ChIP-Seq_ESCs_Human0.88819893
96ARNT_22903824_ChIP-Seq_MCF-7_Human0.88636608
97WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.88452337
98ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.88351370
99POU3F2_20337985_ChIP-ChIP_501MEL_Human0.88302823
100MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.87237941
101ER_23166858_ChIP-Seq_MCF-7_Human0.86779344
102* POU3F1_26484290_ChIP-Seq_ESCss_Mouse0.86217358
103WT1_25993318_ChIP-Seq_PODOCYTE_Human0.85250041
104CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.85228260
105SETDB1_19884257_ChIP-Seq_MESCs_Mouse0.85182296
106NR3C1_21868756_ChIP-Seq_MCF10A_Human0.84794813
107YAP1_20516196_ChIP-Seq_MESCs_Mouse0.84414154
108STAT3_23295773_ChIP-Seq_U87_Human0.83961926
109CTCF_27219007_Chip-Seq_Bcells_Human0.83323304
110WT1_19549856_ChIP-ChIP_CCG9911_Human0.81956522
111RUNX1_26923725_Chip-Seq_HPCs_Mouse0.81658535
112FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.81109196
113KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.80378135
114TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.79620793
115EP300_21415370_ChIP-Seq_HL-1_Mouse0.78768534
116PRDM14_20953172_ChIP-Seq_ESCs_Human0.78684012
117SOX9_26525672_Chip-Seq_Limbbuds_Mouse0.78604029
118AHR_22903824_ChIP-Seq_MCF-7_Human0.78466155
119SOX9_26525672_Chip-Seq_HEART_Mouse0.77476261
120TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.77269213
121ESR1_15608294_ChIP-ChIP_MCF-7_Human0.76276248
122PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.76103420

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.67642098
2MP0004859_abnormal_synaptic_plasticity4.18597348
3MP0005423_abnormal_somatic_nervous4.13437673
4MP0006276_abnormal_autonomic_nervous3.26843108
5MP0003635_abnormal_synaptic_transmissio3.19371195
6MP0003122_maternal_imprinting2.96279898
7MP0000778_abnormal_nervous_system2.91348260
8MP0002063_abnormal_learning/memory/cond2.70267168
9MP0004270_analgesia2.68834287
10MP0009745_abnormal_behavioral_response2.55737998
11MP0002064_seizures2.50718234
12MP0009046_muscle_twitch2.44486258
13MP0005645_abnormal_hypothalamus_physiol2.34808229
14MP0001968_abnormal_touch/_nociception2.32165867
15MP0002572_abnormal_emotion/affect_behav2.30442900
16MP0001486_abnormal_startle_reflex2.28538755
17MP0002734_abnormal_mechanical_nocicepti2.25168166
18MP0002184_abnormal_innervation2.24579307
19MP0001529_abnormal_vocalization2.20634820
20MP0002272_abnormal_nervous_system2.04520494
21MP0001984_abnormal_olfaction1.99921239
22MP0001440_abnormal_grooming_behavior1.96733554
23MP0002733_abnormal_thermal_nociception1.93403487
24MP0005646_abnormal_pituitary_gland1.90985994
25MP0002067_abnormal_sensory_capabilities1.88184594
26MP0002557_abnormal_social/conspecific_i1.86968240
27MP0002736_abnormal_nociception_after1.86428054
28MP0002735_abnormal_chemical_nociception1.72023054
29MP0000955_abnormal_spinal_cord1.70583163
30MP0001970_abnormal_pain_threshold1.67777140
31MP0004858_abnormal_nervous_system1.64873952
32MP0002653_abnormal_ependyma_morphology1.63430810
33MP0004742_abnormal_vestibular_system1.63204070
34MP0004811_abnormal_neuron_physiology1.60827233
35MP0003567_abnormal_fetal_cardiomyocyte1.60807754
36MP0002882_abnormal_neuron_morphology1.57563980
37MP0001501_abnormal_sleep_pattern1.53805752
38MP0000631_abnormal_neuroendocrine_gland1.52967340
39MP0005386_behavior/neurological_phenoty1.45913155
40MP0004924_abnormal_behavior1.45913155
41MP0001905_abnormal_dopamine_level1.44844707
42MP0001502_abnormal_circadian_rhythm1.42590270
43MP0006292_abnormal_olfactory_placode1.42039650
44MP0004142_abnormal_muscle_tone1.39895809
45MP0005394_taste/olfaction_phenotype1.39454710
46MP0005499_abnormal_olfactory_system1.39454710
47MP0002638_abnormal_pupillary_reflex1.39413637
48MP0008569_lethality_at_weaning1.39017602
49MP0002152_abnormal_brain_morphology1.38807629
50MP0003121_genomic_imprinting1.38077373
51MP0002249_abnormal_larynx_morphology1.36934672
52MP0002066_abnormal_motor_capabilities/c1.35598765
53MP0000733_abnormal_muscle_development1.33507079
54MP0002751_abnormal_autonomic_nervous1.31833802
55MP0003329_amyloid_beta_deposits1.27197740
56MP0008995_early_reproductive_senescence1.26784563
57MP0002102_abnormal_ear_morphology1.26142155
58MP0002234_abnormal_pharynx_morphology1.24798924
59MP0000749_muscle_degeneration1.22672639
60MP0004885_abnormal_endolymph1.22591567
61MP0000751_myopathy1.21648759
62MP0002752_abnormal_somatic_nervous1.20934252
63MP0000750_abnormal_muscle_regeneration1.17674033
64MP0008877_abnormal_DNA_methylation1.16614130
65MP0003861_abnormal_nervous_system1.16433696
66MP0002837_dystrophic_cardiac_calcinosis1.10058496
67MP0000026_abnormal_inner_ear1.08390588
68MP0003938_abnormal_ear_development1.07665127
69MP0010386_abnormal_urinary_bladder1.07377024
70MP0008789_abnormal_olfactory_epithelium1.06028036
71MP0002909_abnormal_adrenal_gland1.04860423
72MP0010030_abnormal_orbit_morphology1.02565632
73MP0005551_abnormal_eye_electrophysiolog1.01949565
74MP0003787_abnormal_imprinting1.01263858
75MP0003136_yellow_coat_color1.00661491
76MP0005187_abnormal_penis_morphology0.99432882
77MP0001346_abnormal_lacrimal_gland0.98921311
78MP0006072_abnormal_retinal_apoptosis0.98232742
79MP0000759_abnormal_skeletal_muscle0.97763392
80MP0002822_catalepsy0.97158595
81MP0001963_abnormal_hearing_physiology0.94774252
82MP0002069_abnormal_eating/drinking_beha0.94487789
83MP0003137_abnormal_impulse_conducting0.93532781
84MP0000049_abnormal_middle_ear0.93071748
85MP0004215_abnormal_myocardial_fiber0.92808775
86MP0002106_abnormal_muscle_physiology0.92288144
87MP0003634_abnormal_glial_cell0.90233957
88MP0003119_abnormal_digestive_system0.89617515
89MP0003385_abnormal_body_wall0.87561373
90MP0001188_hyperpigmentation0.86030030
91MP0000537_abnormal_urethra_morphology0.83853019
92MP0002229_neurodegeneration0.83431495
93MP0000534_abnormal_ureter_morphology0.83424884
94MP0005369_muscle_phenotype0.82900965
95MP0005409_darkened_coat_color0.82801555
96MP0001485_abnormal_pinna_reflex0.82560801
97MP0002163_abnormal_gland_morphology0.82374142
98MP0003115_abnormal_respiratory_system0.80113337
99MP0002282_abnormal_trachea_morphology0.79882326
100MP0005253_abnormal_eye_physiology0.78939561
101MP0004084_abnormal_cardiac_muscle0.78896918
102MP0002108_abnormal_muscle_morphology0.78756422
103MP0003890_abnormal_embryonic-extraembry0.78667827
104MP0000538_abnormal_urinary_bladder0.78341219
105MP0008961_abnormal_basal_metabolism0.77576369
106MP0003942_abnormal_urinary_system0.77292588
107MP0004085_abnormal_heartbeat0.76665450
108MP0003632_abnormal_nervous_system0.76358960
109MP0004133_heterotaxia0.75274798
110MP0003937_abnormal_limbs/digits/tail_de0.74699233
111MP0001943_abnormal_respiration0.74385940
112MP0002697_abnormal_eye_size0.72582700
113MP0003879_abnormal_hair_cell0.72334575
114MP0003935_abnormal_craniofacial_develop0.72138818
115MP0002233_abnormal_nose_morphology0.71862506
116MP0004145_abnormal_muscle_electrophysio0.70198280
117MP0003690_abnormal_glial_cell0.69828153
118MP0003631_nervous_system_phenotype0.69327857
119MP0003183_abnormal_peptide_metabolism0.68919208
120MP0001986_abnormal_taste_sensitivity0.67995775
121MP0002081_perinatal_lethality0.67746547
122MP0005171_absent_coat_pigmentation0.66285325
123MP0002082_postnatal_lethality0.65237495
124MP0010770_preweaning_lethality0.65237495
125MP0001299_abnormal_eye_distance/0.64106952

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)5.33681773
2Popliteal pterygium (HP:0009756)5.24379054
3Myokymia (HP:0002411)5.15447342
4Type 2 muscle fiber atrophy (HP:0003554)4.84017862
5Focal seizures (HP:0007359)4.34023805
6Muscle fiber atrophy (HP:0100295)4.27750558
7Polyphagia (HP:0002591)4.19331764
8Abnormality of placental membranes (HP:0011409)4.14059980
9Amniotic constriction ring (HP:0009775)4.14059980
10Failure to thrive in infancy (HP:0001531)4.04548688
11Aplasia of the musculature (HP:0100854)3.99294314
12Akinesia (HP:0002304)3.68329970
13Epileptic encephalopathy (HP:0200134)3.64496922
14Supernumerary spleens (HP:0009799)3.50943636
15Abnormal eating behavior (HP:0100738)3.49983977
16Visual hallucinations (HP:0002367)3.48292682
17Fatigable weakness (HP:0003473)3.40258335
18Abnormality of the neuromuscular junction (HP:0003398)3.40258335
19Progressive cerebellar ataxia (HP:0002073)3.38013474
20Atonic seizures (HP:0010819)3.30712115
21Febrile seizures (HP:0002373)3.29914711
22Oligodactyly (hands) (HP:0001180)3.27273147
23Amblyopia (HP:0000646)3.20733135
24Weak cry (HP:0001612)3.13015383
25Anomalous pulmonary venous return (HP:0010772)3.12565351
26Absence seizures (HP:0002121)3.11836269
27Supranuclear gaze palsy (HP:0000605)3.11167876
28Limb dystonia (HP:0002451)3.09120380
29Oligodactyly (HP:0012165)3.07653750
30Ankle clonus (HP:0011448)3.05559161
31Esotropia (HP:0000565)3.03547410
32Malignant hyperthermia (HP:0002047)3.03440740
33Fibular aplasia (HP:0002990)2.94518602
34Aplasia/Hypoplasia of the brainstem (HP:0007362)2.92146040
35Hypoplasia of the brainstem (HP:0002365)2.92146040
36Dialeptic seizures (HP:0011146)2.91899577
37Rib fusion (HP:0000902)2.90986587
38Sleep apnea (HP:0010535)2.89179747
39Broad-based gait (HP:0002136)2.86242309
40Thin ribs (HP:0000883)2.74206734
41Depressed nasal tip (HP:0000437)2.65045105
42Abnormality of the labia minora (HP:0012880)2.63829243
43Absent septum pellucidum (HP:0001331)2.62155465
44Abnormality of the pulmonary veins (HP:0011718)2.59864371
45Hemiparesis (HP:0001269)2.59328021
46Intestinal atresia (HP:0011100)2.55859622
47Lissencephaly (HP:0001339)2.54729754
48Generalized tonic-clonic seizures (HP:0002069)2.53692542
49Exotropia (HP:0000577)2.53582317
50Narrow nasal bridge (HP:0000446)2.53195500
51Drooling (HP:0002307)2.51767233
52Excessive salivation (HP:0003781)2.51767233
53Aplasia/Hypoplasia involving the musculature (HP:0001460)2.51271771
54Specific learning disability (HP:0001328)2.50387321
55Hypoplastic heart (HP:0001961)2.49465237
56Gowers sign (HP:0003391)2.48241377
57Progressive inability to walk (HP:0002505)2.44040573
58Abnormal hair whorl (HP:0010721)2.43847401
59Agitation (HP:0000713)2.39401198
60Abnormality of the septum pellucidum (HP:0007375)2.37780575
61Pheochromocytoma (HP:0002666)2.36683434
62Mutism (HP:0002300)2.36542907
63Action tremor (HP:0002345)2.36010254
64Split foot (HP:0001839)2.34573403
65Cortical dysplasia (HP:0002539)2.30987994
66Distal arthrogryposis (HP:0005684)2.29684063
67Spastic gait (HP:0002064)2.26949718
68Pterygium (HP:0001059)2.26478249
69Megalencephaly (HP:0001355)2.25414099
70Cystic hygroma (HP:0000476)2.24872806
71Calcaneovalgus deformity (HP:0001848)2.23256647
72Truncal ataxia (HP:0002078)2.22760890
73Impaired vibration sensation in the lower limbs (HP:0002166)2.22325978
74Abnormality of the corticospinal tract (HP:0002492)2.21646231
75Aplasia involving bones of the extremities (HP:0009825)2.21564590
76Aplasia involving bones of the upper limbs (HP:0009823)2.21564590
77Aplasia of the phalanges of the hand (HP:0009802)2.21564590
78Abnormality of the intervertebral disk (HP:0005108)2.21170959
79Calf muscle hypertrophy (HP:0008981)2.20419303
80Poor suck (HP:0002033)2.19943031
81Anterior segment dysgenesis (HP:0007700)2.19639372
82Short palpebral fissure (HP:0012745)2.19106034
83Urinary urgency (HP:0000012)2.15675895
84Hypoplastic nipples (HP:0002557)2.15399913
85Poor eye contact (HP:0000817)2.13550850
86Abnormality of the parathyroid morphology (HP:0011766)2.12275386
87Esophageal atresia (HP:0002032)2.11987716
88Abnormality of the phalanges of the 2nd finger (HP:0009541)2.11446307
89Anxiety (HP:0000739)2.11164506
90Abnormality of the aortic arch (HP:0012303)2.10689142
91Round ear (HP:0100830)2.08922856
92Neuroendocrine neoplasm (HP:0100634)2.08672843
93Hypoventilation (HP:0002791)2.06375470
94Depression (HP:0000716)2.04733309
95Growth hormone deficiency (HP:0000824)2.03443386
96Inability to walk (HP:0002540)2.02832783
97Peripheral hypomyelination (HP:0007182)2.02762058
98Hyperventilation (HP:0002883)2.00444370
99Subaortic stenosis (HP:0001682)2.00199463
100Abnormality of the left ventricular outflow tract (HP:0011103)2.00199463
101Gait imbalance (HP:0002141)1.99112575
102Deformed tarsal bones (HP:0008119)1.95877260
103Double outlet right ventricle (HP:0001719)1.94590900
104Congenital malformation of the right heart (HP:0011723)1.94590900
105Labial hypoplasia (HP:0000066)1.92414234
106Sudden death (HP:0001699)1.92339893
107EEG with generalized epileptiform discharges (HP:0011198)1.90965237
108Fetal akinesia sequence (HP:0001989)1.90168430
109Acute necrotizing encephalopathy (HP:0006965)1.90041753
110Patellar aplasia (HP:0006443)1.88932811
111Generalized hypotonia (HP:0001290)1.88018456
112Epileptiform EEG discharges (HP:0011182)1.87384582
113Neoplasm of the heart (HP:0100544)1.86442213
114Atelectasis (HP:0100750)1.85371381
115Muscle hypertrophy of the lower extremities (HP:0008968)1.84596932
116Cutaneous syndactyly (HP:0012725)1.83450762
117Urinary bladder sphincter dysfunction (HP:0002839)1.82601315
118Lower limb muscle weakness (HP:0007340)1.82514140
119Termporal pattern (HP:0011008)1.82450498
120Insidious onset (HP:0003587)1.82450498
121Symphalangism affecting the phalanges of the hand (HP:0009773)1.81957656
122Hypsarrhythmia (HP:0002521)1.81921338
123Annular pancreas (HP:0001734)1.81478880
124Congenital diaphragmatic hernia (HP:0000776)1.81367029
125Morphological abnormality of the middle ear (HP:0008609)1.80989720
126Dysdiadochokinesis (HP:0002075)1.80190088
127Partial agenesis of the corpus callosum (HP:0001338)1.79917702
128Absent speech (HP:0001344)1.79579611
129Abnormality of the phalanges of the hallux (HP:0010057)1.79535518
130Midline defect of the nose (HP:0004122)1.79292542
131Aplasia/Hypoplasia of the spleen (HP:0010451)1.78124750
132Impaired social interactions (HP:0000735)1.77879322
133Abnormal social behavior (HP:0012433)1.77879322
134Left ventricular hypertrophy (HP:0001712)1.77550467
135Cutaneous finger syndactyly (HP:0010554)1.76834013
136Retinal dysplasia (HP:0007973)1.76423348
137High anterior hairline (HP:0009890)1.75033531
138Easy fatigability (HP:0003388)1.74577748
139Protruding tongue (HP:0010808)1.74548037
140Genital tract atresia (HP:0001827)1.74443906
141Nasal speech (HP:0001611)1.74367992
142Pachygyria (HP:0001302)1.74119996
143Autism (HP:0000717)1.73978598
144Prolonged QT interval (HP:0001657)1.73390167
145Gastrointestinal atresia (HP:0002589)1.73330219
146Spina bifida occulta (HP:0003298)1.73306158
147Incomplete penetrance (HP:0003829)1.73048392
148Myotonia (HP:0002486)1.72497255
149Wrist flexion contracture (HP:0001239)1.72205157
150Adducted thumb (HP:0001181)1.71915193
151Diminished movement (HP:0002374)1.71586452
152Thyroid-stimulating hormone excess (HP:0002925)1.71530491
153Vaginal atresia (HP:0000148)1.71297004
154Hyperthyroidism (HP:0000836)1.70835941
155Neoplasm of the peripheral nervous system (HP:0100007)1.70760970
156Dysmetria (HP:0001310)1.70459637
157Turricephaly (HP:0000262)1.70443793
158Septo-optic dysplasia (HP:0100842)1.70324108
159Abnormality of the calf musculature (HP:0001430)1.69790162
160Hypercortisolism (HP:0001578)1.69685353
161Hip contracture (HP:0003273)1.69205753
162Abnormal ciliary motility (HP:0012262)1.69061078
163Heterochromia iridis (HP:0001100)1.68693700
164Torticollis (HP:0000473)1.68448476
165Abnormal mitochondria in muscle tissue (HP:0008316)1.68437540
166Morphological abnormality of the inner ear (HP:0011390)1.68193760
167Morphological abnormality of the pyramidal tract (HP:0002062)1.68160020
168Abnormality of the lower motor neuron (HP:0002366)1.67970984
169Hypoplastic female external genitalia (HP:0012815)1.67693993
170Respiratory insufficiency due to muscle weakness (HP:0002747)1.66386412
171Amyotrophic lateral sclerosis (HP:0007354)1.66188432
172Bowel diverticulosis (HP:0005222)1.66144485
173Vertebral fusion (HP:0002948)1.65273694
174Sporadic (HP:0003745)1.65048444
175Aplasia/Hypoplasia of the patella (HP:0006498)1.64845308
176Absent phalangeal crease (HP:0006109)1.64564101
177Renovascular hypertension (HP:0100817)1.64328201
178Gaze-evoked nystagmus (HP:0000640)1.63687451
179Hyporeflexia of lower limbs (HP:0002600)1.60658761

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK14.74010479
2MUSK3.94350177
3MAP3K93.19258366
4NTRK23.15445489
5NTRK33.13883604
6CASK3.02482726
7MINK12.59843896
8MAP3K42.44037878
9UHMK12.32011924
10MAP3K122.29786038
11MAPK132.28086957
12KSR12.13517559
13SIK32.00137513
14PAK61.98989853
15MOS1.97995283
16MAP2K71.96159038
17DYRK21.95318228
18EPHA41.89190012
19CDK191.87432926
20BCR1.83429083
21PHKG21.79535478
22PHKG11.79535478
23TNIK1.75498742
24WNK31.73343799
25EPHB21.62294243
26PNCK1.60840162
27SIK21.54347264
28MAP3K101.49847945
29TYRO31.48968045
30PRPF4B1.42597652
31MAP2K41.37677753
32PLK41.33629232
33CDK51.33301241
34DAPK21.33128748
35LIMK11.27643528
36ERBB31.23832989
37OXSR11.16170107
38SGK2231.13710997
39SGK4941.13710997
40PBK1.11688871
41FGFR21.09832507
42BMPR1B1.08601959
43CDK181.07616144
44DYRK1A1.03304553
45IRAK21.02521833
46DYRK31.02167525
47DDR21.01855423
48CDK150.97333372
49PAK30.96654731
50PRKCG0.94349570
51CDK80.93844402
52CDK140.93735599
53CDK11A0.90660446
54GRK50.90395350
55CSNK1G20.89433833
56ICK0.85156664
57LMTK20.82283474
58CSNK1G30.81742296
59MAP3K70.77984682
60CCNB10.77659647
61EPHA30.77023679
62DAPK10.76722491
63ROCK20.74346335
64NEK60.74165219
65CAMK1G0.71927740
66PKN10.71476932
67LATS20.71284742
68CAMK2G0.70990429
69ADRBK10.70971652
70BCKDK0.69704140
71CAMK2A0.68663378
72PTK20.68401952
73NTRK10.68261695
74PLK20.66470903
75STK390.65965790
76ERBB20.64195937
77CAMK2B0.63876505
78CSNK1D0.63374208
79KSR20.63325007
80NME10.63132170
81TNK20.62447297
82SGK20.62397213
83PINK10.62313867
84PKN20.61793566
85CAMK2D0.61715171
86MARK20.61006322
87OBSCN0.59349841
88BRD40.58612647
89GRK70.58519648
90TAOK20.57938032
91ROCK10.57781507
92PRKCZ0.56964596
93PDGFRA0.56895913
94RPS6KA20.56766854
95INSRR0.56213324
96CSNK1A1L0.56173436
97DYRK1B0.55634740
98FES0.53019495
99MAP3K50.52968771
100PIK3CA0.51558844
101WNK40.51125745
102MAPK90.48848957
103SRPK10.48551402
104PRKD30.48377090
105MAPK100.47293550
106CDK90.45653465
107CAMKK20.44353533
108PRKCE0.43950357
109CSNK1G10.43523556
110CSNK1E0.43345368
111AURKA0.43344921
112CAMK10.43239502
113PRKG10.43159935
114ARAF0.40916285
115CAMK1D0.40765843
116CDK20.40231215
117YES10.39613974
118STK110.39585282
119CAMKK10.39141253
120FER0.38750872
121RET0.38616002
122GSK3B0.38148608
123MAP2K10.36410612
124SGK10.35916708
125CDC42BPA0.35367682
126CAMK40.32747031
127MAPK40.32501038
128FYN0.31504245
129PRKACA0.30298030
130WNK10.30226202
131RPS6KA30.29935849
132FGR0.28556588

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.07527357
2Synaptic vesicle cycle_Homo sapiens_hsa047213.34740907
3GABAergic synapse_Homo sapiens_hsa047272.72740786
4Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.57067853
5Axon guidance_Homo sapiens_hsa043602.46601389
6Glutamatergic synapse_Homo sapiens_hsa047242.40733771
7Oxidative phosphorylation_Homo sapiens_hsa001902.29907910
8Morphine addiction_Homo sapiens_hsa050322.21814092
9Circadian entrainment_Homo sapiens_hsa047132.21540676
10Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.13758295
11Cardiac muscle contraction_Homo sapiens_hsa042602.10601979
12Parkinsons disease_Homo sapiens_hsa050122.01478164
13Dopaminergic synapse_Homo sapiens_hsa047282.00204108
14Olfactory transduction_Homo sapiens_hsa047401.95878227
15Collecting duct acid secretion_Homo sapiens_hsa049661.94841673
16Taste transduction_Homo sapiens_hsa047421.85645031
17Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.82140517
18Cocaine addiction_Homo sapiens_hsa050301.81839190
19Serotonergic synapse_Homo sapiens_hsa047261.79695665
20Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.75844497
21Long-term potentiation_Homo sapiens_hsa047201.75096541
22Amphetamine addiction_Homo sapiens_hsa050311.71991532
23Cholinergic synapse_Homo sapiens_hsa047251.69802420
24Alzheimers disease_Homo sapiens_hsa050101.60487765
25Insulin secretion_Homo sapiens_hsa049111.60308589
26Gap junction_Homo sapiens_hsa045401.58107193
27Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.56064770
28Long-term depression_Homo sapiens_hsa047301.55016607
29Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.47970694
30Salivary secretion_Homo sapiens_hsa049701.47849923
31Huntingtons disease_Homo sapiens_hsa050161.45235936
32Oxytocin signaling pathway_Homo sapiens_hsa049211.42298094
33Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.39458800
34Gastric acid secretion_Homo sapiens_hsa049711.32188415
35Renin secretion_Homo sapiens_hsa049241.31265491
36Vibrio cholerae infection_Homo sapiens_hsa051101.24941724
37Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.21074263
38Aldosterone synthesis and secretion_Homo sapiens_hsa049251.19600241
39Calcium signaling pathway_Homo sapiens_hsa040201.19478579
40GnRH signaling pathway_Homo sapiens_hsa049121.17030234
41Melanogenesis_Homo sapiens_hsa049161.16162365
42Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.15422277
43Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.12784525
44ErbB signaling pathway_Homo sapiens_hsa040121.06304058
45Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.05352579
46Phototransduction_Homo sapiens_hsa047441.05337654
47Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.05214192
48Hedgehog signaling pathway_Homo sapiens_hsa043400.98669512
49Bile secretion_Homo sapiens_hsa049760.94588296
50Basal cell carcinoma_Homo sapiens_hsa052170.90588442
51Wnt signaling pathway_Homo sapiens_hsa043100.89173980
52Butanoate metabolism_Homo sapiens_hsa006500.86847672
53Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.86693522
54Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.86275213
55Lysine degradation_Homo sapiens_hsa003100.84655132
56cAMP signaling pathway_Homo sapiens_hsa040240.84017440
57Dilated cardiomyopathy_Homo sapiens_hsa054140.83322310
58Alcoholism_Homo sapiens_hsa050340.79906291
59Estrogen signaling pathway_Homo sapiens_hsa049150.79444491
60Cell cycle_Homo sapiens_hsa041100.75759638
61Oocyte meiosis_Homo sapiens_hsa041140.75473854
62MAPK signaling pathway_Homo sapiens_hsa040100.73129622
63Glioma_Homo sapiens_hsa052140.73086618
64Renal cell carcinoma_Homo sapiens_hsa052110.70064052
65Fanconi anemia pathway_Homo sapiens_hsa034600.69121496
66Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.68734448
67Type II diabetes mellitus_Homo sapiens_hsa049300.67830587
68mRNA surveillance pathway_Homo sapiens_hsa030150.67431661
69Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.67339523
70Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.66526948
71cGMP-PKG signaling pathway_Homo sapiens_hsa040220.65121526
72Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.64938932
73Phospholipase D signaling pathway_Homo sapiens_hsa040720.63497960
742-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.61326468
75RNA polymerase_Homo sapiens_hsa030200.61241579
76Circadian rhythm_Homo sapiens_hsa047100.60391584
77Ovarian steroidogenesis_Homo sapiens_hsa049130.59503268
78AMPK signaling pathway_Homo sapiens_hsa041520.59179431
79Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.59083103
80Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.58589866
81Hippo signaling pathway_Homo sapiens_hsa043900.57179740
82Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.56816349
83Basal transcription factors_Homo sapiens_hsa030220.55851284
84Base excision repair_Homo sapiens_hsa034100.55358635
85Phosphatidylinositol signaling system_Homo sapiens_hsa040700.54819965
86Colorectal cancer_Homo sapiens_hsa052100.54570980
87Vascular smooth muscle contraction_Homo sapiens_hsa042700.53430663
88Endometrial cancer_Homo sapiens_hsa052130.53341586
89Ras signaling pathway_Homo sapiens_hsa040140.52771497
90Choline metabolism in cancer_Homo sapiens_hsa052310.52160321
91Phagosome_Homo sapiens_hsa041450.51738312
92Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.51720684
93Neurotrophin signaling pathway_Homo sapiens_hsa047220.48896905
94Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.48846423
95Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.44324165
96Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.43021765
97MicroRNAs in cancer_Homo sapiens_hsa052060.42277821
98Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.41692873
99SNARE interactions in vesicular transport_Homo sapiens_hsa041300.40904753
100Endocytosis_Homo sapiens_hsa041440.40484269
101Prion diseases_Homo sapiens_hsa050200.40376697
102Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.39602118
103Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.38891195
104TGF-beta signaling pathway_Homo sapiens_hsa043500.38437904
105Arginine and proline metabolism_Homo sapiens_hsa003300.37377342
106Sphingolipid signaling pathway_Homo sapiens_hsa040710.37128418
107Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.36726592
108Rap1 signaling pathway_Homo sapiens_hsa040150.36177062
109Thyroid hormone signaling pathway_Homo sapiens_hsa049190.34828149
110Pancreatic secretion_Homo sapiens_hsa049720.33434433
111VEGF signaling pathway_Homo sapiens_hsa043700.33087909
112Notch signaling pathway_Homo sapiens_hsa043300.32080677
113Type I diabetes mellitus_Homo sapiens_hsa049400.29744382
114Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.28223482
115Thyroid hormone synthesis_Homo sapiens_hsa049180.28211619
116Insulin signaling pathway_Homo sapiens_hsa049100.26433168
117Dorso-ventral axis formation_Homo sapiens_hsa043200.25585631
118Melanoma_Homo sapiens_hsa052180.24435778
119Tight junction_Homo sapiens_hsa045300.22287491

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