Rank | Gene Set | Z-score |
---|---|---|
1 | positive regulation of gamma-delta T cell activation (GO:0046645) | 7.50708487 |
2 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 7.49385704 |
3 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 7.49385704 |
4 | antigen processing and presentation of endogenous antigen (GO:0019883) | 6.76564917 |
5 | negative T cell selection (GO:0043383) | 6.56715265 |
6 | negative thymic T cell selection (GO:0045060) | 6.51787970 |
7 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 6.21074687 |
8 | regulation of gamma-delta T cell differentiation (GO:0045586) | 5.99740917 |
9 | positive thymic T cell selection (GO:0045059) | 5.96137347 |
10 | negative regulation of cell killing (GO:0031342) | 5.91204153 |
11 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 5.91204153 |
12 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 5.74641315 |
13 | response to interleukin-15 (GO:0070672) | 5.68479704 |
14 | cellular response to interleukin-15 (GO:0071350) | 5.55712357 |
15 | regulation of gamma-delta T cell activation (GO:0046643) | 5.53337660 |
16 | regulation of isotype switching to IgG isotypes (GO:0048302) | 5.53202790 |
17 | thymic T cell selection (GO:0045061) | 5.41198885 |
18 | regulation of T cell tolerance induction (GO:0002664) | 5.23926810 |
19 | positive T cell selection (GO:0043368) | 5.22524559 |
20 | T cell migration (GO:0072678) | 5.19805253 |
21 | leukocyte aggregation (GO:0070486) | 5.13626785 |
22 | regulation of B cell receptor signaling pathway (GO:0050855) | 5.09305242 |
23 | T cell selection (GO:0045058) | 5.03171378 |
24 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 4.98657273 |
25 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 4.98657273 |
26 | modulation by symbiont of host immune response (GO:0052553) | 4.98657273 |
27 | positive regulation by symbiont of host defense response (GO:0052509) | 4.98657273 |
28 | modulation by symbiont of host defense response (GO:0052031) | 4.98657273 |
29 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 4.98657273 |
30 | interferon-gamma production (GO:0032609) | 4.91594105 |
31 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 4.87103696 |
32 | positive regulation of tolerance induction (GO:0002645) | 4.49082778 |
33 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 4.40007565 |
34 | T cell receptor signaling pathway (GO:0050852) | 4.38621897 |
35 | detection of other organism (GO:0098543) | 4.35605609 |
36 | detection of bacterium (GO:0016045) | 4.34899072 |
37 | antigen processing and presentation via MHC class Ib (GO:0002475) | 4.31279735 |
38 | regulation of alpha-beta T cell proliferation (GO:0046640) | 4.29684153 |
39 | T cell costimulation (GO:0031295) | 4.26260427 |
40 | positive regulation of type I interferon-mediated signaling pathway (GO:0060340) | 4.25871583 |
41 | lymphocyte costimulation (GO:0031294) | 4.21455126 |
42 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 4.21049459 |
43 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 4.11345881 |
44 | regulation of tolerance induction (GO:0002643) | 4.10471442 |
45 | antigen receptor-mediated signaling pathway (GO:0050851) | 4.10274912 |
46 | response to interferon-alpha (GO:0035455) | 4.06511269 |
47 | tolerance induction (GO:0002507) | 4.06498040 |
48 | neutrophil activation involved in immune response (GO:0002283) | 4.01991693 |
49 | response to type I interferon (GO:0034340) | 4.00611133 |
50 | type I interferon signaling pathway (GO:0060337) | 3.97166310 |
51 | cellular response to type I interferon (GO:0071357) | 3.97166310 |
52 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 3.97144306 |
53 | leukocyte migration involved in inflammatory response (GO:0002523) | 3.97139194 |
54 | regulation of T cell receptor signaling pathway (GO:0050856) | 3.95198145 |
55 | regulation of B cell differentiation (GO:0045577) | 3.94143069 |
56 | regulation of regulatory T cell differentiation (GO:0045589) | 3.89673762 |
57 | regulation of type I interferon-mediated signaling pathway (GO:0060338) | 3.81434084 |
58 | B cell receptor signaling pathway (GO:0050853) | 3.75207295 |
59 | regulation of response to interferon-gamma (GO:0060330) | 3.72775269 |
60 | sequestering of actin monomers (GO:0042989) | 3.71425711 |
61 | respiratory burst (GO:0045730) | 3.69914645 |
62 | positive regulation of isotype switching (GO:0045830) | 3.68442789 |
63 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 3.68301957 |
64 | positive regulation of interleukin-2 production (GO:0032743) | 3.66526328 |
65 | macrophage activation involved in immune response (GO:0002281) | 3.63530634 |
66 | detection of external biotic stimulus (GO:0098581) | 3.62247436 |
67 | regulation of interferon-gamma-mediated signaling pathway (GO:0060334) | 3.61645934 |
68 | regulation of isotype switching (GO:0045191) | 3.57343047 |
69 | mast cell activation (GO:0045576) | 3.55181298 |
70 | interferon-gamma-mediated signaling pathway (GO:0060333) | 3.52021285 |
71 | regulation of natural killer cell mediated immunity (GO:0002715) | 3.50453423 |
72 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 3.50453423 |
73 | leukocyte cell-cell adhesion (GO:0007159) | 3.50298708 |
74 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 3.48627991 |
75 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 3.48627991 |
76 | NIK/NF-kappaB signaling (GO:0038061) | 3.45604955 |
77 | response to host immune response (GO:0052572) | 3.40957715 |
78 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.40957715 |
79 | response to peptidoglycan (GO:0032494) | 3.40112949 |
80 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 3.39078318 |
81 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.37686118 |
82 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.35060309 |
83 | positive regulation of humoral immune response (GO:0002922) | 3.32310644 |
84 | JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397) | 3.32279216 |
85 | regulation of immunoglobulin mediated immune response (GO:0002889) | 3.30475976 |
86 | neutrophil activation (GO:0042119) | 3.29270937 |
87 | regulation of B cell mediated immunity (GO:0002712) | 3.27895287 |
88 | response to host (GO:0075136) | 3.25998593 |
89 | response to host defenses (GO:0052200) | 3.25998593 |
90 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.25998593 |
91 | cellular response to interferon-beta (GO:0035458) | 3.25739362 |
92 | positive regulation of DNA recombination (GO:0045911) | 3.25490853 |
93 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.24098862 |
94 | positive regulation of B cell differentiation (GO:0045579) | 3.23492348 |
95 | positive regulation of B cell mediated immunity (GO:0002714) | 3.22151673 |
96 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 3.22151673 |
97 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.21654717 |
98 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 3.20574495 |
99 | activated T cell proliferation (GO:0050798) | 3.18522231 |
100 | negative regulation of antigen receptor-mediated signaling pathway (GO:0050858) | 3.17286351 |
101 | negative regulation of phagocytosis (GO:0050765) | 3.16040954 |
102 | T cell homeostasis (GO:0043029) | 3.15411820 |
103 | negative regulation of T cell mediated immunity (GO:0002710) | 3.14179099 |
104 | natural killer cell activation (GO:0030101) | 3.13822589 |
105 | detection of molecule of bacterial origin (GO:0032490) | 3.12522233 |
106 | detection of biotic stimulus (GO:0009595) | 3.12511227 |
107 | lymph node development (GO:0048535) | 3.10734863 |
108 | myeloid dendritic cell activation (GO:0001773) | 3.10409811 |
109 | positive regulation of immunoglobulin production (GO:0002639) | 3.08347303 |
110 | regulation of immunoglobulin production (GO:0002637) | 3.08265963 |
111 | negative regulation of innate immune response (GO:0045824) | 3.07189227 |
112 | lymphocyte migration (GO:0072676) | 3.06316994 |
113 | immunoglobulin mediated immune response (GO:0016064) | 3.06077059 |
114 | granulocyte activation (GO:0036230) | 3.05732455 |
115 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 3.05298030 |
116 | immune response-activating cell surface receptor signaling pathway (GO:0002429) | 3.04390270 |
117 | regulation of defense response to virus by virus (GO:0050690) | 3.03003001 |
118 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 3.01678849 |
119 | regulation of mast cell degranulation (GO:0043304) | 3.01622523 |
120 | mature B cell differentiation (GO:0002335) | 3.01159403 |
121 | negative regulation of interleukin-12 production (GO:0032695) | 3.00851916 |
122 | alpha-beta T cell activation (GO:0046631) | 3.00279241 |
123 | T cell differentiation (GO:0030217) | 2.99805454 |
124 | regulation of cell killing (GO:0031341) | 2.98757533 |
125 | negative regulation of T cell receptor signaling pathway (GO:0050860) | 2.98626928 |
126 | positive regulation of Cdc42 GTPase activity (GO:0043089) | 2.98323067 |
127 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 2.98291331 |
128 | positive regulation of interleukin-8 secretion (GO:2000484) | 2.97256876 |
129 | negative regulation of type 2 immune response (GO:0002829) | 2.97131040 |
130 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 2.96758740 |
131 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 2.96520009 |
132 | regulation of T cell mediated cytotoxicity (GO:0001914) | 2.96164755 |
133 | negative regulation of erythrocyte differentiation (GO:0045647) | 2.94937227 |
134 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 2.94348608 |
135 | response to interferon-beta (GO:0035456) | 2.94167483 |
136 | protein localization to endosome (GO:0036010) | 2.91506780 |
137 | positive regulation of cell killing (GO:0031343) | 2.90796964 |
138 | T cell activation (GO:0042110) | 2.90275466 |
139 | regulation of leukocyte degranulation (GO:0043300) | 2.86902027 |
140 | barbed-end actin filament capping (GO:0051016) | 2.80401152 |
141 | negative regulation of glycoprotein biosynthetic process (GO:0010561) | 2.80206030 |
142 | modulation by virus of host process (GO:0019054) | 2.78895456 |
143 | negative regulation of viral genome replication (GO:0045071) | 2.76450922 |
144 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 2.71338953 |
145 | cellular response to virus (GO:0098586) | 2.67093702 |
146 | regulation of regulated secretory pathway (GO:1903305) | 2.66250774 |
147 | myeloid cell activation involved in immune response (GO:0002275) | 2.65830320 |
148 | regulation of mast cell activation involved in immune response (GO:0033006) | 2.61189148 |
149 | negative regulation of cytokine production involved in immune response (GO:0002719) | 2.60585621 |
150 | virion assembly (GO:0019068) | 2.60461078 |
151 | signal complex assembly (GO:0007172) | 2.59470165 |
152 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 2.55961345 |
153 | modulation by symbiont of host cellular process (GO:0044068) | 2.55347606 |
154 | cellular extravasation (GO:0045123) | 2.53032434 |
155 | pentose-phosphate shunt (GO:0006098) | 2.52968144 |
156 | viral protein processing (GO:0019082) | 2.52398856 |
157 | interferon-gamma secretion (GO:0072643) | 2.52183147 |
158 | regulation of T-helper 2 cell differentiation (GO:0045628) | 2.50794280 |
159 | protein maturation by protein folding (GO:0022417) | 2.50753815 |
160 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 2.49907635 |
161 | amino sugar catabolic process (GO:0046348) | 2.47747744 |
162 | negative regulation of glycoprotein metabolic process (GO:1903019) | 2.47596702 |
163 | negative regulation of viral entry into host cell (GO:0046597) | 2.46298887 |
164 | leukocyte degranulation (GO:0043299) | 2.45499004 |
165 | dendritic cell chemotaxis (GO:0002407) | 2.43775928 |
Rank | Gene Set | Z-score |
---|---|---|
1 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 6.85781528 |
2 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.55759582 |
3 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 5.45856268 |
4 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 4.47058749 |
5 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 4.01979296 |
6 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 3.46793996 |
7 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.46778303 |
8 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 3.41206267 |
9 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 3.37532209 |
10 | * RUNX_20019798_ChIP-Seq_JUKART_Human | 3.31099302 |
11 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 3.18394779 |
12 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 3.18222122 |
13 | MYC_22102868_ChIP-Seq_BL_Human | 3.12543178 |
14 | MYB_26560356_Chip-Seq_TH2_Human | 3.02388691 |
15 | MAF_26560356_Chip-Seq_TH1_Human | 2.85147982 |
16 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.76450845 |
17 | MYB_26560356_Chip-Seq_TH1_Human | 2.58182562 |
18 | * UTX_26944678_Chip-Seq_JUKART_Human | 2.45005812 |
19 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.43016231 |
20 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.42130334 |
21 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.41840139 |
22 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.40144877 |
23 | * SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 2.36215862 |
24 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.35427366 |
25 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.33979330 |
26 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.32571714 |
27 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.31160213 |
28 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.26410730 |
29 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.18744106 |
30 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.14331682 |
31 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 2.13695714 |
32 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 2.06230311 |
33 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 2.04422836 |
34 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.03814765 |
35 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.96266340 |
36 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.94066778 |
37 | MAF_26560356_Chip-Seq_TH2_Human | 1.93239995 |
38 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.88703102 |
39 | * RACK7_27058665_Chip-Seq_MCF-7_Human | 1.87695850 |
40 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.83697804 |
41 | * GATA3_27048872_Chip-Seq_THYMUS_Human | 1.82611834 |
42 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.80175189 |
43 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.75786561 |
44 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.67334729 |
45 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.67089688 |
46 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.66797877 |
47 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 1.63155643 |
48 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.63080353 |
49 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.62644781 |
50 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.61163393 |
51 | P68_20966046_ChIP-Seq_HELA_Human | 1.58643872 |
52 | SPI1_23127762_ChIP-Seq_K562_Human | 1.54614647 |
53 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.53478568 |
54 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.53111757 |
55 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.49429658 |
56 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.48131643 |
57 | * SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.47491840 |
58 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.47117235 |
59 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.45556782 |
60 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.44498474 |
61 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.42843220 |
62 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.42674590 |
63 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.42044659 |
64 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.40071738 |
65 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.39847937 |
66 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.37887569 |
67 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.37513573 |
68 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.36784933 |
69 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.35980806 |
70 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.35679046 |
71 | * KDM2B_26808549_Chip-Seq_DND41_Human | 1.32423930 |
72 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.32392519 |
73 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.31024918 |
74 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.30545626 |
75 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.30034169 |
76 | KDM2B_26808549_Chip-Seq_K562_Human | 1.28293222 |
77 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.28117707 |
78 | * SMC4_20622854_ChIP-Seq_HELA_Human | 1.27384016 |
79 | * SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.25919664 |
80 | * CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.24946256 |
81 | GATA3_26560356_Chip-Seq_TH2_Human | 1.24210013 |
82 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.24125800 |
83 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.23634981 |
84 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.22699655 |
85 | * CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.22675099 |
86 | SA1_27219007_Chip-Seq_Bcells_Human | 1.22022803 |
87 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.20829498 |
88 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.20680347 |
89 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.20125384 |
90 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.19199620 |
91 | * GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.18903424 |
92 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.18726785 |
93 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 1.18059561 |
94 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.16447988 |
95 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.14511284 |
96 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.14332204 |
97 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.11664402 |
98 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.11205760 |
99 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.10417176 |
100 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.09733985 |
101 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.09705875 |
102 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.08707604 |
103 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.08200742 |
104 | * PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.07503429 |
105 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 1.07320399 |
106 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.07151361 |
107 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.07149224 |
108 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.04405819 |
109 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.03695380 |
110 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.03621049 |
111 | GATA1_22025678_ChIP-Seq_K562_Human | 1.02428591 |
112 | PHF8_20622854_ChIP-Seq_HELA_Human | 1.02072344 |
113 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.00862923 |
114 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 0.99837929 |
115 | CTCF_21964334_Chip-Seq_Bcells_Human | 0.99761276 |
116 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.99464284 |
117 | VDR_23849224_ChIP-Seq_CD4+_Human | 0.97873059 |
118 | * CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.94908123 |
119 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.94688689 |
120 | * PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.94172041 |
121 | * SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.92945269 |
122 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.90792596 |
123 | FOXP3_21729870_ChIP-Seq_TREG_Human | 0.87111866 |
124 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 0.82419491 |
125 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.82285426 |
126 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.80779482 |
127 | * FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.80435469 |
128 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.79441048 |
129 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.78206757 |
130 | SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human | 0.77479363 |
131 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.76825916 |
132 | E2F7_22180533_ChIP-Seq_HELA_Human | 0.76747438 |
133 | * RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.76028069 |
134 | * Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 0.75980786 |
135 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 0.74047689 |
136 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.72033466 |
137 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.71642507 |
138 | P300_27268052_Chip-Seq_Bcells_Human | 0.68254143 |
139 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 0.68248136 |
140 | VDR_24787735_ChIP-Seq_THP-1_Human | 0.67230550 |
141 | ETS1_22383799_ChIP-Seq_G1ME_Mouse | 0.66189931 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003763_abnormal_thymus_physiology | 4.66467252 |
2 | MP0005671_abnormal_response_to | 4.31730314 |
3 | MP0001835_abnormal_antigen_presentation | 4.19373678 |
4 | MP0000685_abnormal_immune_system | 3.98906198 |
5 | MP0009785_altered_susceptibility_to | 3.37561178 |
6 | MP0001800_abnormal_humoral_immune | 3.37522239 |
7 | MP0001790_abnormal_immune_system | 3.34919690 |
8 | MP0005387_immune_system_phenotype | 3.34919690 |
9 | MP0005000_abnormal_immune_tolerance | 3.12328427 |
10 | MP0002723_abnormal_immune_serum | 2.95088672 |
11 | MP0002420_abnormal_adaptive_immunity | 2.94830319 |
12 | MP0001819_abnormal_immune_cell | 2.90864748 |
13 | MP0002452_abnormal_antigen_presenting | 2.87930495 |
14 | MP0002166_altered_tumor_susceptibility | 2.80752001 |
15 | MP0005025_abnormal_response_to | 2.78683391 |
16 | MP0002398_abnormal_bone_marrow | 2.70427576 |
17 | MP0003436_decreased_susceptibility_to | 2.66504082 |
18 | MP0008260_abnormal_autophagy | 2.64940087 |
19 | MP0006082_CNS_inflammation | 2.58951620 |
20 | MP0003724_increased_susceptibility_to | 2.53476439 |
21 | MP0009333_abnormal_splenocyte_physiolog | 2.53127623 |
22 | MP0002148_abnormal_hypersensitivity_rea | 2.45341182 |
23 | MP0000716_abnormal_immune_system | 2.45082796 |
24 | MP0009840_abnormal_foam_cell | 2.38229630 |
25 | MP0002405_respiratory_system_inflammati | 2.36089829 |
26 | MP0001873_stomach_inflammation | 2.34385035 |
27 | MP0004858_abnormal_nervous_system | 2.28337343 |
28 | MP0002006_tumorigenesis | 2.27102956 |
29 | MP0002419_abnormal_innate_immunity | 2.25317607 |
30 | MP0010155_abnormal_intestine_physiology | 2.23586647 |
31 | MP0000689_abnormal_spleen_morphology | 2.21716222 |
32 | MP0002396_abnormal_hematopoietic_system | 2.20936582 |
33 | MP0002722_abnormal_immune_system | 2.20690399 |
34 | MP0004947_skin_inflammation | 2.10627346 |
35 | MP0000703_abnormal_thymus_morphology | 2.09788340 |
36 | MP0003866_abnormal_defecation | 2.07956623 |
37 | MP0003300_gastrointestinal_ulcer | 2.02561559 |
38 | MP0002653_abnormal_ependyma_morphology | 2.01569171 |
39 | MP0002429_abnormal_blood_cell | 2.01031538 |
40 | MP0002933_joint_inflammation | 1.96765869 |
41 | MP0003705_abnormal_hypodermis_morpholog | 1.91734118 |
42 | MP0005464_abnormal_platelet_physiology | 1.90568777 |
43 | MP0001845_abnormal_inflammatory_respons | 1.85790437 |
44 | MP0004510_myositis | 1.85249663 |
45 | MP0005451_abnormal_body_composition | 1.72390889 |
46 | MP0003303_peritoneal_inflammation | 1.69957133 |
47 | MP0001853_heart_inflammation | 1.61332109 |
48 | MP0003329_amyloid_beta_deposits | 1.57036783 |
49 | MP0004808_abnormal_hematopoietic_stem | 1.50539634 |
50 | MP0000465_gastrointestinal_hemorrhage | 1.47767877 |
51 | MP0000858_altered_metastatic_potential | 1.47382307 |
52 | MP0000604_amyloidosis | 1.39653618 |
53 | MP0003075_altered_response_to | 1.39230485 |
54 | MP0008469_abnormal_protein_level | 1.36965421 |
55 | MP0001533_abnormal_skeleton_physiology | 1.36238154 |
56 | MP0005310_abnormal_salivary_gland | 1.33556645 |
57 | MP0001958_emphysema | 1.33307037 |
58 | MP0005083_abnormal_biliary_tract | 1.28959866 |
59 | MP0008438_abnormal_cutaneous_collagen | 1.26327204 |
60 | MP0001542_abnormal_bone_strength | 1.25416130 |
61 | MP0003448_altered_tumor_morphology | 1.22647620 |
62 | MP0000490_abnormal_crypts_of | 1.17733313 |
63 | MP0005397_hematopoietic_system_phenotyp | 1.13577397 |
64 | MP0001545_abnormal_hematopoietic_system | 1.13577397 |
65 | MP0005075_abnormal_melanosome_morpholog | 1.10839061 |
66 | MP0001849_ear_inflammation | 1.06579877 |
67 | MP0001851_eye_inflammation | 1.06156500 |
68 | MP0008004_abnormal_stomach_pH | 1.05386395 |
69 | MP0003806_abnormal_nucleotide_metabolis | 1.05321363 |
70 | MP0005174_abnormal_tail_pigmentation | 1.04903843 |
71 | MP0002998_abnormal_bone_remodeling | 1.01919747 |
72 | MP0004883_abnormal_blood_vessel | 1.00212628 |
73 | MP0005023_abnormal_wound_healing | 0.99288243 |
74 | MP0003045_fibrosis | 0.99277965 |
75 | MP0005058_abnormal_lysosome_morphology | 0.94612586 |
76 | MP0002019_abnormal_tumor_incidence | 0.92525715 |
77 | MP0002132_abnormal_respiratory_system | 0.92486763 |
78 | MP0005377_hearing/vestibular/ear_phenot | 0.91600314 |
79 | MP0003878_abnormal_ear_physiology | 0.91600314 |
80 | MP0009764_decreased_sensitivity_to | 0.89809343 |
81 | MP0000767_abnormal_smooth_muscle | 0.89628481 |
82 | MP0005164_abnormal_response_to | 0.89571497 |
83 | MP0008874_decreased_physiological_sensi | 0.87504640 |
84 | MP0004381_abnormal_hair_follicle | 0.87246871 |
85 | MP0003011_delayed_dark_adaptation | 0.86942112 |
86 | MP0002009_preneoplasia | 0.80073133 |
87 | MP0003123_paternal_imprinting | 0.79770444 |
88 | MP0005257_abnormal_intraocular_pressure | 0.79185974 |
89 | MP0002138_abnormal_hepatobiliary_system | 0.78204502 |
90 | MP0000343_altered_response_to | 0.77428936 |
91 | MP0000750_abnormal_muscle_regeneration | 0.76546704 |
92 | MP0002254_reproductive_system_inflammat | 0.76401279 |
93 | MP0006054_spinal_hemorrhage | 0.75809115 |
94 | MP0009763_increased_sensitivity_to | 0.75522536 |
95 | MP0003172_abnormal_lysosome_physiology | 0.74427214 |
96 | MP0005381_digestive/alimentary_phenotyp | 0.71470028 |
97 | MP0010352_gastrointestinal_tract_polyps | 0.71057834 |
98 | MP0003879_abnormal_hair_cell | 0.70011088 |
99 | MP0000678_abnormal_parathyroid_gland | 0.68316484 |
100 | MP0002136_abnormal_kidney_physiology | 0.67853856 |
101 | MP0001915_intracranial_hemorrhage | 0.67852618 |
102 | MP0009278_abnormal_bone_marrow | 0.67354119 |
103 | MP0009765_abnormal_xenobiotic_induced | 0.66061584 |
104 | MP0003191_abnormal_cellular_cholesterol | 0.65801272 |
105 | MP0003795_abnormal_bone_structure | 0.65040346 |
106 | MP0005623_abnormal_meninges_morphology | 0.64969694 |
107 | MP0003453_abnormal_keratinocyte_physiol | 0.62341999 |
108 | MP0002796_impaired_skin_barrier | 0.62146648 |
109 | MP0000477_abnormal_intestine_morphology | 0.61582683 |
110 | MP0003279_aneurysm | 0.61534223 |
111 | MP0001663_abnormal_digestive_system | 0.60765982 |
112 | MP0000249_abnormal_blood_vessel | 0.60444565 |
113 | MP0005390_skeleton_phenotype | 0.58703805 |
114 | MP0010234_abnormal_vibrissa_follicle | 0.57204172 |
115 | MP0003091_abnormal_cell_migration | 0.52786528 |
116 | MP0001191_abnormal_skin_condition | 0.52590946 |
117 | MP0002095_abnormal_skin_pigmentation | 0.51574450 |
118 | MP0000015_abnormal_ear_pigmentation | 0.50449432 |
119 | MP0005166_decreased_susceptibility_to | 0.49979143 |
120 | MP0003566_abnormal_cell_adhesion | 0.49436801 |
121 | MP0003828_pulmonary_edema | 0.48836338 |
122 | MP0001348_abnormal_lacrimal_gland | 0.48509804 |
123 | MP0000609_abnormal_liver_physiology | 0.45663835 |
124 | MP0001243_abnormal_dermal_layer | 0.45258714 |
125 | MP0008961_abnormal_basal_metabolism | 0.44017479 |
126 | MP0002693_abnormal_pancreas_physiology | 0.42764065 |
127 | MP0001216_abnormal_epidermal_layer | 0.41528493 |
128 | MP0003183_abnormal_peptide_metabolism | 0.39691761 |
129 | MP0008007_abnormal_cellular_replicative | 0.38603371 |
130 | MP0002277_abnormal_respiratory_mucosa | 0.37865735 |
131 | MP0000313_abnormal_cell_death | 0.37284749 |
132 | MP0009643_abnormal_urine_homeostasis | 0.35373367 |
133 | MP0000367_abnormal_coat/_hair | 0.34260447 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Elevated erythrocyte sedimentation rate (HP:0003565) | 5.81270042 |
2 | Recurrent bronchitis (HP:0002837) | 5.61709482 |
3 | T lymphocytopenia (HP:0005403) | 5.60532994 |
4 | Abnormality of T cell number (HP:0011839) | 5.44005359 |
5 | Chronic otitis media (HP:0000389) | 5.42719480 |
6 | Myositis (HP:0100614) | 4.98974208 |
7 | IgM deficiency (HP:0002850) | 4.79496689 |
8 | Nasal polyposis (HP:0100582) | 4.76253401 |
9 | Abnormality of T cells (HP:0002843) | 4.60889030 |
10 | Eczematoid dermatitis (HP:0000976) | 4.42760487 |
11 | Abnormality of the nasal mucosa (HP:0000433) | 4.40627788 |
12 | Stomatitis (HP:0010280) | 4.39602854 |
13 | Recurrent fungal infections (HP:0002841) | 4.39567317 |
14 | Recurrent cutaneous fungal infections (HP:0011370) | 4.19777269 |
15 | Chronic mucocutaneous candidiasis (HP:0002728) | 4.19777269 |
16 | Recurrent viral infections (HP:0004429) | 4.14316160 |
17 | Recurrent abscess formation (HP:0002722) | 4.03530502 |
18 | IgG deficiency (HP:0004315) | 4.01864130 |
19 | Severe combined immunodeficiency (HP:0004430) | 3.96410325 |
20 | Pustule (HP:0200039) | 3.91035714 |
21 | Panhypogammaglobulinemia (HP:0003139) | 3.86598863 |
22 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.86128647 |
23 | Combined immunodeficiency (HP:0005387) | 3.76751571 |
24 | Lymphopenia (HP:0001888) | 3.74645701 |
25 | Agammaglobulinemia (HP:0004432) | 3.73435525 |
26 | Abnormality of T cell physiology (HP:0011840) | 3.60301710 |
27 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 3.58093621 |
28 | Chronic diarrhea (HP:0002028) | 3.55886725 |
29 | Orchitis (HP:0100796) | 3.45784596 |
30 | Optic neuritis (HP:0100653) | 3.44389843 |
31 | Retrobulbar optic neuritis (HP:0100654) | 3.44389843 |
32 | Thrombocytosis (HP:0001894) | 3.35242468 |
33 | Meningitis (HP:0001287) | 3.32544879 |
34 | Vasculitis (HP:0002633) | 3.32227671 |
35 | Peritonitis (HP:0002586) | 3.28678020 |
36 | Autoimmune hemolytic anemia (HP:0001890) | 3.25297651 |
37 | Inflammation of the large intestine (HP:0002037) | 3.22391350 |
38 | Recurrent sinusitis (HP:0011108) | 3.22249077 |
39 | Bronchitis (HP:0012387) | 3.20810147 |
40 | Recurrent skin infections (HP:0001581) | 3.20707787 |
41 | Increased IgM level (HP:0003496) | 3.20702448 |
42 | Recurrent bacterial skin infections (HP:0005406) | 3.19131055 |
43 | Chronic sinusitis (HP:0011109) | 3.17166939 |
44 | Hypochromic microcytic anemia (HP:0004840) | 3.16752815 |
45 | Gastrointestinal inflammation (HP:0004386) | 3.14492539 |
46 | Abnormality of eosinophils (HP:0001879) | 3.11365277 |
47 | Amyloidosis (HP:0011034) | 3.08090465 |
48 | Autoimmune thrombocytopenia (HP:0001973) | 3.03738186 |
49 | Joint swelling (HP:0001386) | 3.02572323 |
50 | Mediastinal lymphadenopathy (HP:0100721) | 3.00637259 |
51 | Thyroiditis (HP:0100646) | 2.98772960 |
52 | Spontaneous hematomas (HP:0007420) | 2.96913442 |
53 | Leukocytosis (HP:0001974) | 2.96778095 |
54 | Abnormality of B cell number (HP:0010975) | 2.94296874 |
55 | B lymphocytopenia (HP:0010976) | 2.94296874 |
56 | Hemoptysis (HP:0002105) | 2.94066538 |
57 | Gastrointestinal stroma tumor (HP:0100723) | 2.89770362 |
58 | Urticaria (HP:0001025) | 2.86597142 |
59 | Hypergammaglobulinemia (HP:0010702) | 2.84644402 |
60 | Pulmonary infiltrates (HP:0002113) | 2.83789929 |
61 | IgA deficiency (HP:0002720) | 2.79365062 |
62 | Vertebral compression fractures (HP:0002953) | 2.76601957 |
63 | Loss of speech (HP:0002371) | 2.74320442 |
64 | Interstitial pulmonary disease (HP:0006530) | 2.74203524 |
65 | Emphysema (HP:0002097) | 2.73569220 |
66 | Colitis (HP:0002583) | 2.72622253 |
67 | Abnormality of the fingertips (HP:0001211) | 2.72188051 |
68 | Eosinophilia (HP:0001880) | 2.71713787 |
69 | Increased IgE level (HP:0003212) | 2.70511225 |
70 | Hypochromic anemia (HP:0001931) | 2.69271708 |
71 | Chronic obstructive pulmonary disease (HP:0006510) | 2.66293321 |
72 | Obstructive lung disease (HP:0006536) | 2.66293321 |
73 | Encephalitis (HP:0002383) | 2.64495746 |
74 | Premature rupture of membranes (HP:0001788) | 2.60983121 |
75 | Granulocytopenia (HP:0001913) | 2.59960712 |
76 | Episodic fever (HP:0001954) | 2.55814143 |
77 | Arterial thrombosis (HP:0004420) | 2.55167827 |
78 | Cellulitis (HP:0100658) | 2.50852435 |
79 | Abnormality of macrophages (HP:0004311) | 2.50437091 |
80 | Lymphoma (HP:0002665) | 2.45206780 |
81 | Protrusio acetabuli (HP:0003179) | 2.45044513 |
82 | Systemic lupus erythematosus (HP:0002725) | 2.43728452 |
83 | Keratoconjunctivitis sicca (HP:0001097) | 2.42640151 |
84 | Prolonged bleeding time (HP:0003010) | 2.42447100 |
85 | Papilloma (HP:0012740) | 2.42191361 |
86 | Verrucae (HP:0200043) | 2.42191361 |
87 | Epistaxis (HP:0000421) | 2.38679347 |
88 | Petechiae (HP:0000967) | 2.33188039 |
89 | Abnormality of the peritoneum (HP:0002585) | 2.25604078 |
90 | Hypoplasia of the thymus (HP:0000778) | 2.25304741 |
91 | Keratoconjunctivitis (HP:0001096) | 2.20959767 |
92 | Gastrointestinal infarctions (HP:0005244) | 2.17913452 |
93 | Chest pain (HP:0100749) | 2.15095971 |
94 | Segmental peripheral demyelination/remyelination (HP:0003481) | 2.14966507 |
95 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.14421771 |
96 | Skin ulcer (HP:0200042) | 2.14016276 |
97 | Cheilitis (HP:0100825) | 2.12395399 |
98 | Gingivitis (HP:0000230) | 2.12109689 |
99 | Hemorrhage of the eye (HP:0011885) | 2.11411962 |
100 | Hepatosplenomegaly (HP:0001433) | 2.11170029 |
101 | Recurrent otitis media (HP:0000403) | 2.10287933 |
102 | Cervical subluxation (HP:0003308) | 2.10199974 |
103 | Basal cell carcinoma (HP:0002671) | 2.09083163 |
104 | Progressive neurologic deterioration (HP:0002344) | 2.07999908 |
105 | Vacuolated lymphocytes (HP:0001922) | 2.07568518 |
106 | Periodontitis (HP:0000704) | 2.05875115 |
107 | Polygenic inheritance (HP:0010982) | 2.04088259 |
108 | Abnormality of glycolipid metabolism (HP:0010969) | 2.03826191 |
109 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.03826191 |
110 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.03826191 |
111 | Sepsis (HP:0100806) | 2.02886404 |
112 | Restrictive lung disease (HP:0002091) | 2.01608462 |
113 | Pulmonary embolism (HP:0002204) | 2.00886933 |
114 | Dysostosis multiplex (HP:0000943) | 2.00134696 |
115 | Hypertriglyceridemia (HP:0002155) | 1.99838820 |
116 | Gingival bleeding (HP:0000225) | 1.99292869 |
117 | Supranuclear gaze palsy (HP:0000605) | 1.98210918 |
118 | Hypertensive crisis (HP:0100735) | 1.96660420 |
119 | Increased serum ferritin (HP:0003281) | 1.95341583 |
120 | Anorexia (HP:0002039) | 1.95217834 |
121 | Arthralgia (HP:0002829) | 1.94791709 |
122 | Abnormality of the pericardium (HP:0001697) | 1.93712952 |
123 | Hematochezia (HP:0002573) | 1.92356418 |
124 | Abnormality of the prostate (HP:0008775) | 1.91807522 |
125 | Increased connective tissue (HP:0009025) | 1.90588420 |
126 | Increased variability in muscle fiber diameter (HP:0003557) | 1.90530664 |
127 | Polycythemia (HP:0001901) | 1.89446947 |
128 | Increased cerebral lipofuscin (HP:0011813) | 1.87776007 |
129 | Bronchiectasis (HP:0002110) | 1.86455086 |
130 | Skin rash (HP:0000988) | 1.85964532 |
131 | Dilatation of the ascending aorta (HP:0005111) | 1.84396023 |
132 | Microcytic anemia (HP:0001935) | 1.83814655 |
133 | Joint hemorrhage (HP:0005261) | 1.83666363 |
134 | Growth hormone excess (HP:0000845) | 1.83646122 |
135 | Purpura (HP:0000979) | 1.83526921 |
136 | Malnutrition (HP:0004395) | 1.82749023 |
137 | Acne (HP:0001061) | 1.82517949 |
138 | Increased density of long bones (HP:0006392) | 1.82146316 |
139 | Gastrointestinal dysmotility (HP:0002579) | 1.81702016 |
140 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 1.79497995 |
141 | Thin bony cortex (HP:0002753) | 1.74098773 |
142 | Abnormal hemoglobin (HP:0011902) | 1.72880474 |
143 | Long palpebral fissure (HP:0000637) | 1.72680365 |
144 | Premature loss of primary teeth (HP:0006323) | 1.71565616 |
145 | Glomerulopathy (HP:0100820) | 1.71226635 |
146 | Abnormality of alkaline phosphatase activity (HP:0004379) | 1.71146959 |
147 | Metaphyseal cupping (HP:0003021) | 1.70669408 |
148 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 1.70512966 |
149 | Abnormality of skeletal muscle fiber size (HP:0012084) | 1.69708126 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MAP4K1 | 5.74197112 |
2 | TXK | 4.75792576 |
3 | JAK3 | 3.45197075 |
4 | TYK2 | 3.13214944 |
5 | FGFR4 | 3.05542346 |
6 | IKBKE | 2.99119515 |
7 | ZAP70 | 2.95021526 |
8 | ITK | 2.60877260 |
9 | STK10 | 2.52294892 |
10 | KIT | 2.36197158 |
11 | TBK1 | 2.33412683 |
12 | JAK1 | 2.32204024 |
13 | MAP3K14 | 2.15998153 |
14 | NLK | 2.15152336 |
15 | GRK6 | 2.02807374 |
16 | SMG1 | 2.02755210 |
17 | NME2 | 2.02562207 |
18 | PRPF4B | 1.98494123 |
19 | TEC | 1.90806025 |
20 | BLK | 1.87672099 |
21 | LCK | 1.87127725 |
22 | BTK | 1.81132112 |
23 | FGFR3 | 1.77448528 |
24 | MAP3K13 | 1.72692116 |
25 | TGFBR2 | 1.71547807 |
26 | KDR | 1.69100287 |
27 | IRAK4 | 1.66837214 |
28 | SYK | 1.64261553 |
29 | CSK | 1.56039411 |
30 | MAP3K12 | 1.48687666 |
31 | ARAF | 1.46913241 |
32 | HCK | 1.40852894 |
33 | CDK19 | 1.39112944 |
34 | IKBKB | 1.34720445 |
35 | LRRK2 | 1.29770825 |
36 | CSF1R | 1.28502118 |
37 | TAOK2 | 1.26287402 |
38 | MARK3 | 1.24930863 |
39 | ERN1 | 1.23407060 |
40 | ICK | 1.23084407 |
41 | MST4 | 1.22860226 |
42 | RIPK1 | 1.16509652 |
43 | FLT3 | 1.12222701 |
44 | SIK3 | 1.10047607 |
45 | PAK4 | 1.07362997 |
46 | MAP3K1 | 1.04915210 |
47 | LIMK1 | 1.02349015 |
48 | EPHA2 | 1.01859874 |
49 | FGR | 1.01741347 |
50 | TESK2 | 1.01004831 |
51 | PRKCH | 0.99502800 |
52 | LYN | 0.98635109 |
53 | RPS6KA4 | 0.95425784 |
54 | EPHA3 | 0.93193651 |
55 | KSR2 | 0.92151212 |
56 | FES | 0.91812412 |
57 | PRKCQ | 0.90416959 |
58 | LMTK2 | 0.88647498 |
59 | IRAK3 | 0.87006209 |
60 | JAK2 | 0.86540309 |
61 | PIM1 | 0.86335532 |
62 | MAP3K10 | 0.85831805 |
63 | SIK2 | 0.85096445 |
64 | DYRK1B | 0.83286461 |
65 | PKN2 | 0.82784981 |
66 | CHUK | 0.82343311 |
67 | MAP3K6 | 0.81351444 |
68 | EEF2K | 0.81063183 |
69 | EPHB1 | 0.80988640 |
70 | STK38 | 0.80868389 |
71 | MAP2K3 | 0.80801862 |
72 | CAMKK1 | 0.79310980 |
73 | CLK1 | 0.79227709 |
74 | CDC42BPA | 0.78652489 |
75 | PDPK1 | 0.77529197 |
76 | TGFBR1 | 0.72214837 |
77 | BMX | 0.67591382 |
78 | RPS6KA2 | 0.66388429 |
79 | EPHB2 | 0.64673146 |
80 | IRAK1 | 0.62558131 |
81 | MAP2K6 | 0.60123741 |
82 | PTK2 | 0.58144546 |
83 | TNK2 | 0.56615387 |
84 | TRIB3 | 0.55102212 |
85 | PRKD2 | 0.53595871 |
86 | MYLK | 0.52677545 |
87 | TTN | 0.52229530 |
88 | PAK1 | 0.51862379 |
89 | BCKDK | 0.51001237 |
90 | HIPK2 | 0.50703283 |
91 | RIPK4 | 0.49782006 |
92 | PRKD3 | 0.48829617 |
93 | BRAF | 0.47503127 |
94 | MAP3K8 | 0.47079962 |
95 | NEK9 | 0.46120974 |
96 | PTK2B | 0.45921269 |
97 | MAP3K7 | 0.45904917 |
98 | VRK2 | 0.43722703 |
99 | RPS6KC1 | 0.43610041 |
100 | RPS6KL1 | 0.43610041 |
101 | TAOK3 | 0.42067206 |
102 | MAP2K4 | 0.42014662 |
103 | PRKD1 | 0.40766683 |
104 | DYRK2 | 0.39894599 |
105 | PDK1 | 0.38629611 |
106 | MAPK11 | 0.38448022 |
107 | IRAK2 | 0.38220442 |
108 | SIK1 | 0.37819130 |
109 | IGF1R | 0.37797187 |
110 | ABL2 | 0.37044271 |
111 | FYN | 0.36544719 |
112 | MAP2K7 | 0.35855211 |
113 | TNIK | 0.34918975 |
114 | MATK | 0.34700228 |
115 | PIM2 | 0.33895899 |
116 | MAP2K2 | 0.33546743 |
117 | TAOK1 | 0.33535666 |
118 | NTRK1 | 0.33023054 |
119 | INSR | 0.32517696 |
120 | MARK2 | 0.32286347 |
121 | ADRBK2 | 0.31527570 |
122 | PDGFRB | 0.30994726 |
123 | CDK4 | 0.30872662 |
124 | PRKCD | 0.28989157 |
125 | MAP3K11 | 0.28053377 |
126 | MAPK12 | 0.27104943 |
127 | MAPK7 | 0.26890093 |
128 | PRKG2 | 0.26738739 |
129 | MAPK4 | 0.26361277 |
130 | ABL1 | 0.24171610 |
131 | MAPK3 | 0.23658759 |
132 | ILK | 0.23027737 |
133 | RPS6KA5 | 0.21487820 |
134 | PTK6 | 0.20611119 |
135 | MAP3K3 | 0.19469192 |
136 | TESK1 | 0.18941360 |
137 | MAPKAPK2 | 0.18370906 |
138 | EGFR | 0.17956695 |
139 | RPS6KA6 | 0.17693860 |
140 | ACVR1B | 0.17519593 |
141 | CDK6 | 0.17212294 |
142 | SRC | 0.14345674 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Primary immunodeficiency_Homo sapiens_hsa05340 | 5.40790339 |
2 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 3.10994292 |
3 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 3.03593884 |
4 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.85411736 |
5 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.84535663 |
6 | Measles_Homo sapiens_hsa05162 | 2.83194655 |
7 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.67246576 |
8 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.61855624 |
9 | Leishmaniasis_Homo sapiens_hsa05140 | 2.42303012 |
10 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.35914961 |
11 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.30397332 |
12 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.30365084 |
13 | Allograft rejection_Homo sapiens_hsa05330 | 2.26391717 |
14 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.17812746 |
15 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 2.04740188 |
16 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.04580769 |
17 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.97760957 |
18 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.91912083 |
19 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.73259372 |
20 | Viral myocarditis_Homo sapiens_hsa05416 | 1.70802942 |
21 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.57972056 |
22 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.49201811 |
23 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.48952508 |
24 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.48082030 |
25 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.42356889 |
26 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.41078784 |
27 | Galactose metabolism_Homo sapiens_hsa00052 | 1.40784724 |
28 | Shigellosis_Homo sapiens_hsa05131 | 1.39859560 |
29 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.39536768 |
30 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.37830409 |
31 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.37064883 |
32 | Influenza A_Homo sapiens_hsa05164 | 1.36564568 |
33 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.32788208 |
34 | Hepatitis B_Homo sapiens_hsa05161 | 1.32171319 |
35 | Malaria_Homo sapiens_hsa05144 | 1.32130337 |
36 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.30156730 |
37 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.29336936 |
38 | Ribosome_Homo sapiens_hsa03010 | 1.26199329 |
39 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.20069081 |
40 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.19882955 |
41 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.16442269 |
42 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.14280228 |
43 | Tuberculosis_Homo sapiens_hsa05152 | 1.12366622 |
44 | Apoptosis_Homo sapiens_hsa04210 | 1.10340376 |
45 | Other glycan degradation_Homo sapiens_hsa00511 | 1.10196519 |
46 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.09447835 |
47 | Legionellosis_Homo sapiens_hsa05134 | 1.06863854 |
48 | Platelet activation_Homo sapiens_hsa04611 | 1.05108642 |
49 | Pertussis_Homo sapiens_hsa05133 | 1.04323509 |
50 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.02106881 |
51 | Hepatitis C_Homo sapiens_hsa05160 | 1.01610549 |
52 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.99083948 |
53 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.95452295 |
54 | HTLV-I infection_Homo sapiens_hsa05166 | 0.92972532 |
55 | Asthma_Homo sapiens_hsa05310 | 0.92661946 |
56 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.92516459 |
57 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.90770308 |
58 | Salmonella infection_Homo sapiens_hsa05132 | 0.88152487 |
59 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.86699403 |
60 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.86205114 |
61 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.85726270 |
62 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.80872768 |
63 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.79149495 |
64 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.78886439 |
65 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.77830502 |
66 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.76556216 |
67 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.75347505 |
68 | Endometrial cancer_Homo sapiens_hsa05213 | 0.73815798 |
69 | Amoebiasis_Homo sapiens_hsa05146 | 0.72700216 |
70 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.70280918 |
71 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.69505280 |
72 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.68159810 |
73 | Colorectal cancer_Homo sapiens_hsa05210 | 0.67841955 |
74 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.67099059 |
75 | Prion diseases_Homo sapiens_hsa05020 | 0.64547926 |
76 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.63499998 |
77 | Bladder cancer_Homo sapiens_hsa05219 | 0.62839944 |
78 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.61368390 |
79 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.60791369 |
80 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.60191278 |
81 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.59219851 |
82 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.59094115 |
83 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.58351192 |
84 | Lysosome_Homo sapiens_hsa04142 | 0.53378344 |
85 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.53353993 |
86 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.52698762 |
87 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.51734310 |
88 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.50946763 |
89 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.50365427 |
90 | Sulfur relay system_Homo sapiens_hsa04122 | 0.49579009 |
91 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.49450430 |
92 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.48281868 |
93 | Endocytosis_Homo sapiens_hsa04144 | 0.47021763 |
94 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.46979536 |
95 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.46642058 |
96 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.43214738 |
97 | Base excision repair_Homo sapiens_hsa03410 | 0.42835051 |
98 | Thyroid cancer_Homo sapiens_hsa05216 | 0.40621609 |
99 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.39780241 |
100 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.38992270 |
101 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.35041008 |
102 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.33691375 |
103 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.33144003 |
104 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.31518563 |
105 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.30795216 |
106 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.29407659 |
107 | * p53 signaling pathway_Homo sapiens_hsa04115 | 0.27536593 |
108 | Pathways in cancer_Homo sapiens_hsa05200 | 0.27042102 |
109 | Insulin resistance_Homo sapiens_hsa04931 | 0.25858114 |
110 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.25616332 |
111 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.25372571 |
112 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.24738375 |
113 | DNA replication_Homo sapiens_hsa03030 | 0.24032789 |
114 | Spliceosome_Homo sapiens_hsa03040 | 0.23702857 |
115 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.22242063 |
116 | Focal adhesion_Homo sapiens_hsa04510 | 0.21842194 |
117 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.21495401 |
118 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.21125040 |
119 | RNA degradation_Homo sapiens_hsa03018 | 0.20899648 |
120 | Adherens junction_Homo sapiens_hsa04520 | 0.20757665 |
121 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.20742436 |
122 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.19436349 |
123 | Phagosome_Homo sapiens_hsa04145 | 0.19156148 |
124 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.17983369 |
125 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.17065216 |