SHTN1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1synaptic vesicle docking involved in exocytosis (GO:0016081)5.39220663
2pyrimidine nucleobase catabolic process (GO:0006208)5.21827007
3nucleobase catabolic process (GO:0046113)4.65780837
4membrane depolarization during cardiac muscle cell action potential (GO:0086012)4.18954163
5cellular potassium ion homeostasis (GO:0030007)4.03735411
6neuronal action potential propagation (GO:0019227)4.00325295
7neuronal ion channel clustering (GO:0045161)3.87105956
8L-amino acid import (GO:0043092)3.64376626
9neurotransmitter transport (GO:0006836)3.52276548
10layer formation in cerebral cortex (GO:0021819)3.50318847
11amino acid import (GO:0043090)3.47756496
12sodium ion export (GO:0071436)3.47614199
13neuron cell-cell adhesion (GO:0007158)3.46069769
14negative regulation of synaptic transmission, GABAergic (GO:0032229)3.45278043
15regulation of neurotransmitter levels (GO:0001505)3.34736403
16neuron-neuron synaptic transmission (GO:0007270)3.33650695
17positive regulation of synapse maturation (GO:0090129)3.26273861
18establishment of mitochondrion localization (GO:0051654)3.26037551
19positive regulation of dendritic spine development (GO:0060999)3.15715381
20positive regulation of dendritic spine morphogenesis (GO:0061003)3.12825430
21neuron recognition (GO:0008038)3.11619124
22negative regulation of dendrite morphogenesis (GO:0050774)3.09950648
23negative regulation of dendrite development (GO:2000171)3.09107578
24regulation of excitatory postsynaptic membrane potential (GO:0060079)3.07987238
25dendrite morphogenesis (GO:0048813)3.07938336
26detection of calcium ion (GO:0005513)3.06530284
27synaptic vesicle maturation (GO:0016188)3.05347132
28positive regulation of membrane potential (GO:0045838)3.05072309
29gamma-aminobutyric acid signaling pathway (GO:0007214)3.00728413
30potassium ion homeostasis (GO:0055075)3.00726002
31regulation of vesicle fusion (GO:0031338)3.00233311
32regulation of neurotransmitter secretion (GO:0046928)3.00041677
33positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.98601077
34regulation of postsynaptic membrane potential (GO:0060078)2.98534626
35central nervous system myelination (GO:0022010)2.98019532
36axon ensheathment in central nervous system (GO:0032291)2.98019532
37synaptic vesicle exocytosis (GO:0016079)2.96643785
38auditory behavior (GO:0031223)2.95457514
39vocalization behavior (GO:0071625)2.93185053
40clathrin coat assembly (GO:0048268)2.92940620
41regulation of synaptic plasticity (GO:0048167)2.92345358
42establishment of synaptic vesicle localization (GO:0097480)2.91171318
43synaptic vesicle transport (GO:0048489)2.91171318
44response to auditory stimulus (GO:0010996)2.89139786
45acidic amino acid transport (GO:0015800)2.88185140
46regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.82829528
47long-term synaptic potentiation (GO:0060291)2.82321440
48regulation of neurotransmitter transport (GO:0051588)2.81950840
49cellular sodium ion homeostasis (GO:0006883)2.81928042
50neuromuscular process controlling posture (GO:0050884)2.81668503
51potassium ion import (GO:0010107)2.78118993
52startle response (GO:0001964)2.77717364
53mitochondrion transport along microtubule (GO:0047497)2.76553580
54establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.76553580
55C4-dicarboxylate transport (GO:0015740)2.76207284
56regulation of synaptic vesicle exocytosis (GO:2000300)2.75492892
57regulation of short-term neuronal synaptic plasticity (GO:0048172)2.74819241
58long-term memory (GO:0007616)2.74301399
59regulation of calcium ion-dependent exocytosis (GO:0017158)2.73291756
60positive regulation of neurotransmitter transport (GO:0051590)2.72159677
61cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.72082650
62regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.71822638
63positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.70076318
64establishment of vesicle localization (GO:0051650)2.68259696
65fatty acid elongation (GO:0030497)2.68039675
66protein localization to synapse (GO:0035418)2.67499065
67long-chain fatty acid biosynthetic process (GO:0042759)2.66031408
68regulation of synapse maturation (GO:0090128)2.64955105
69positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.64946001
70neurotransmitter uptake (GO:0001504)2.64645648
71regulation of synaptic transmission, glutamatergic (GO:0051966)2.64051723
72neurotransmitter-gated ion channel clustering (GO:0072578)2.63801572
73regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.63560318
74axonal fasciculation (GO:0007413)2.63402966
75membrane hyperpolarization (GO:0060081)2.62229837
76ionotropic glutamate receptor signaling pathway (GO:0035235)2.62104229
77positive regulation of neurotransmitter secretion (GO:0001956)2.61406442
78dendritic spine morphogenesis (GO:0060997)2.60259397
79glycosphingolipid biosynthetic process (GO:0006688)2.59949727
80righting reflex (GO:0060013)2.59317129
81signal release (GO:0023061)2.58672858
82neuromuscular process controlling balance (GO:0050885)2.58495632
83glutamate secretion (GO:0014047)2.58167570
84regulation of glutamate receptor signaling pathway (GO:1900449)2.57994727
85gamma-aminobutyric acid transport (GO:0015812)2.57781316
86nerve growth factor signaling pathway (GO:0038180)2.55572395
87presynaptic membrane assembly (GO:0097105)2.53237456
88presynaptic membrane organization (GO:0097090)2.49969678
89proline transport (GO:0015824)2.46501100
90response to nerve growth factor (GO:1990089)2.45151634
91cellular response to nerve growth factor stimulus (GO:1990090)2.45151634
92cellular ketone body metabolic process (GO:0046950)2.43921662
93axon extension (GO:0048675)2.43225169
94locomotory exploration behavior (GO:0035641)2.42717815
95central nervous system projection neuron axonogenesis (GO:0021952)2.42164319
96regulation of synapse structural plasticity (GO:0051823)2.42162034
97cerebellar granule cell differentiation (GO:0021707)2.40628643
98organelle transport along microtubule (GO:0072384)2.39804034
99negative regulation of neurotransmitter transport (GO:0051589)2.39101551
100L-phenylalanine catabolic process (GO:0006559)2.38436630
101erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)2.38436630
102response to lipoprotein particle (GO:0055094)2.37695704
103cerebral cortex radially oriented cell migration (GO:0021799)2.36548695
104neuron remodeling (GO:0016322)2.34408716
105glutamate receptor signaling pathway (GO:0007215)2.33875041
106negative regulation of neurotransmitter secretion (GO:0046929)2.32487028
107regulation of synaptic vesicle transport (GO:1902803)2.31194567
108exploration behavior (GO:0035640)2.28746137
109cell migration in hindbrain (GO:0021535)2.28219386
110neuron projection extension (GO:1990138)2.24184108
111protein localization to endosome (GO:0036010)2.21597597
112positive regulation of filopodium assembly (GO:0051491)2.21380610
113neurotransmitter secretion (GO:0007269)2.20229667
114macroautophagy (GO:0016236)2.18896328
115modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.16042873
116positive regulation by organism of defense response of other organism involved in symbiotic interact2.16042873
117modulation by symbiont of host immune response (GO:0052553)2.16042873
118positive regulation by symbiont of host defense response (GO:0052509)2.16042873
119modulation by symbiont of host defense response (GO:0052031)2.16042873
120modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.16042873
121regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)2.15484605
122apical protein localization (GO:0045176)2.12395105
123vesicle transport along microtubule (GO:0047496)2.11958411
124long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)2.11070787
125semaphorin-plexin signaling pathway (GO:0071526)2.11036231
126postsynaptic membrane organization (GO:0001941)2.11016167
127adult walking behavior (GO:0007628)2.09637144
128positive regulation of cellular amide metabolic process (GO:0034250)2.08978829
129cholesterol efflux (GO:0033344)2.07678732
130regulation of filopodium assembly (GO:0051489)2.06427268
131synapse assembly (GO:0007416)2.05589051
132L-phenylalanine metabolic process (GO:0006558)2.05414018
133erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)2.05414018
134ketone body metabolic process (GO:1902224)2.04938432
135regulation of neuronal synaptic plasticity (GO:0048168)2.04425729
136plasma lipoprotein particle clearance (GO:0034381)2.04362398
137central nervous system neuron axonogenesis (GO:0021955)2.03579960
138phagosome maturation (GO:0090382)2.02623373
139regulation of dendritic spine morphogenesis (GO:0061001)2.01582686
140transmission of nerve impulse (GO:0019226)2.01402942
141regulation of dendritic spine development (GO:0060998)2.00628389
142mating behavior (GO:0007617)1.99875129
143synaptic vesicle endocytosis (GO:0048488)1.99838400
144ensheathment of neurons (GO:0007272)1.99231126
145axon ensheathment (GO:0008366)1.99231126
146synaptic transmission, glutamatergic (GO:0035249)1.98553239
147glycine transport (GO:0015816)1.97997193
148regulation of respiratory gaseous exchange by neurological system process (GO:0002087)1.97908268
149negative regulation of axonogenesis (GO:0050771)1.96288020
150detection of temperature stimulus involved in sensory perception of pain (GO:0050965)1.96190642
151detection of temperature stimulus involved in sensory perception (GO:0050961)1.96190642
152negative regulation of synaptic transmission, glutamatergic (GO:0051967)1.95940590
153regulation of long-term neuronal synaptic plasticity (GO:0048169)1.95635268
154protein carboxylation (GO:0018214)1.95137234
155peptidyl-glutamic acid carboxylation (GO:0017187)1.95137234

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GBX2_23144817_ChIP-Seq_PC3_Human2.82708647
2EZH2_22144423_ChIP-Seq_EOC_Human2.76774568
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.10519327
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.97192476
5SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.93327712
6CDX2_19796622_ChIP-Seq_MESCs_Mouse1.91126027
7MTF2_20144788_ChIP-Seq_MESCs_Mouse1.85563679
8JARID2_20064375_ChIP-Seq_MESCs_Mouse1.84705076
9SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.79982960
10VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.76403946
11DROSHA_22980978_ChIP-Seq_HELA_Human1.73354276
12AR_21572438_ChIP-Seq_LNCaP_Human1.70191948
13SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.68637867
14CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.65953670
15SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.65158112
16RNF2_18974828_ChIP-Seq_MESCs_Mouse1.64474934
17EZH2_18974828_ChIP-Seq_MESCs_Mouse1.64474934
18Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.63473398
19REST_21632747_ChIP-Seq_MESCs_Mouse1.62397787
20TAF15_26573619_Chip-Seq_HEK293_Human1.60961745
21GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.59944039
22EZH2_27294783_Chip-Seq_ESCs_Mouse1.58104974
23SUZ12_27294783_Chip-Seq_ESCs_Mouse1.56760516
24GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.56680583
25JARID2_20075857_ChIP-Seq_MESCs_Mouse1.56246913
26ZNF217_24962896_ChIP-Seq_MCF-7_Human1.54917187
27MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.53808328
28SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.51635734
29EZH2_27304074_Chip-Seq_ESCs_Mouse1.49574489
30CTBP2_25329375_ChIP-Seq_LNCAP_Human1.49161904
31ZFP57_27257070_Chip-Seq_ESCs_Mouse1.48281373
32PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.47681782
33NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.42904590
34RNF2_27304074_Chip-Seq_ESCs_Mouse1.40748732
35ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.37475452
36PIAS1_25552417_ChIP-Seq_VCAP_Human1.36849406
37AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.36597676
38RNF2_27304074_Chip-Seq_NSC_Mouse1.34620350
39CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.34159963
40TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.33778307
41OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.33537773
42AHR_22903824_ChIP-Seq_MCF-7_Human1.33149580
43IGF1R_20145208_ChIP-Seq_DFB_Human1.29895304
44SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.28872583
45SMAD4_21799915_ChIP-Seq_A2780_Human1.28689680
46FUS_26573619_Chip-Seq_HEK293_Human1.27069346
47FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.26931699
48ARNT_22903824_ChIP-Seq_MCF-7_Human1.26745404
49CTBP1_25329375_ChIP-Seq_LNCAP_Human1.26561380
50RARB_27405468_Chip-Seq_BRAIN_Mouse1.26276939
51P300_19829295_ChIP-Seq_ESCs_Human1.24889451
52SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.24218979
53EED_16625203_ChIP-ChIP_MESCs_Mouse1.23375683
54IRF8_21731497_ChIP-ChIP_J774_Mouse1.23352941
55POU3F2_20337985_ChIP-ChIP_501MEL_Human1.23277935
56NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.23113443
57NRF2_20460467_ChIP-Seq_MEFs_Mouse1.23113443
58REST_18959480_ChIP-ChIP_MESCs_Mouse1.22984350
59ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.22718591
60SMAD3_21741376_ChIP-Seq_EPCs_Human1.21084176
61LXR_22158963_ChIP-Seq_LIVER_Mouse1.19661276
62RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.19324010
63YAP1_20516196_ChIP-Seq_MESCs_Mouse1.18991927
64TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.18708851
65CBP_20019798_ChIP-Seq_JUKART_Human1.17544580
66IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.17544580
67NR3C1_23031785_ChIP-Seq_PC12_Mouse1.17085154
68RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.17083563
69CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.14561420
70LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.14350257
71RXR_22158963_ChIP-Seq_LIVER_Mouse1.13131188
72STAT3_23295773_ChIP-Seq_U87_Human1.13080929
73ER_23166858_ChIP-Seq_MCF-7_Human1.12579941
74TP53_18474530_ChIP-ChIP_U2OS_Human1.12281140
75SALL1_21062744_ChIP-ChIP_HESCs_Human1.11894795
76SOX2_21211035_ChIP-Seq_LN229_Gbm1.11815839
77AR_25329375_ChIP-Seq_VCAP_Human1.11504908
78TOP2B_26459242_ChIP-Seq_MCF-7_Human1.10256171
79TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.08937866
80STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.08542045
81MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.07915286
82EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.07514356
83BMI1_23680149_ChIP-Seq_NPCS_Mouse1.07243482
84P53_22387025_ChIP-Seq_ESCs_Mouse1.06448847
85CTNNB1_20460455_ChIP-Seq_HCT116_Human1.05385143
86RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.05243050
87SMAD_19615063_ChIP-ChIP_OVARY_Human1.04638490
88P53_22127205_ChIP-Seq_FIBROBLAST_Human1.04406778
89ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.04265657
90BP1_19119308_ChIP-ChIP_Hs578T_Human1.03914288
91E2F1_18555785_Chip-Seq_ESCs_Mouse1.02130443
92IKZF1_21737484_ChIP-ChIP_HCT116_Human1.02114834
93TP53_16413492_ChIP-PET_HCT116_Human1.01340077
94CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.00869554
95KLF5_20875108_ChIP-Seq_MESCs_Mouse1.00725872
96TAL1_26923725_Chip-Seq_HPCs_Mouse1.00647631
97FLI1_21867929_ChIP-Seq_TH2_Mouse0.99159952
98VDR_24787735_ChIP-Seq_THP-1_Human0.98796055
99IRF8_27001747_Chip-Seq_BMDM_Mouse0.98307514
100TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97435667
101SUZ12_18555785_Chip-Seq_ESCs_Mouse0.97311572
102TCF4_22108803_ChIP-Seq_LS180_Human0.97141098
103HTT_18923047_ChIP-ChIP_STHdh_Human0.96901571
104WT1_25993318_ChIP-Seq_PODOCYTE_Human0.96276466
105TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse0.95799113
106NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.95710051
107SMAD3_21741376_ChIP-Seq_ESCs_Human0.95654400
108TCF4_23295773_ChIP-Seq_U87_Human0.95062037
109ERG_21242973_ChIP-ChIP_JURKAT_Human0.94695579
110BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.94237360
111SMAD4_21741376_ChIP-Seq_HESCs_Human0.93002721
112TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.92874962
113NR3C1_21868756_ChIP-Seq_MCF10A_Human0.91772890
114UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.91621920
115EGR1_19032775_ChIP-ChIP_M12_Human0.91574945
116ESR1_20079471_ChIP-ChIP_T-47D_Human0.89736076
117PRDM14_20953172_ChIP-Seq_ESCs_Human0.89466893
118TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.89078386
119RUNX2_22187159_ChIP-Seq_PCA_Human0.88973050
120RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.87294026
121MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.86815153
122NANOG_18555785_Chip-Seq_ESCs_Mouse0.86183814
123KDM2B_26808549_Chip-Seq_REH_Human0.85668242
124ZNF274_21170338_ChIP-Seq_K562_Hela0.85648887
125CBX2_27304074_Chip-Seq_ESCs_Mouse0.85196338
126FOXA2_19822575_ChIP-Seq_HepG2_Human0.84933840
127AR_19668381_ChIP-Seq_PC3_Human0.84575377
128SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse0.83866907
129BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.83332626
130CMYC_18555785_Chip-Seq_ESCs_Mouse0.83274608

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity3.83195648
2MP0004270_analgesia3.33380346
3MP0003880_abnormal_central_pattern3.02937925
4MP0003329_amyloid_beta_deposits2.68886136
5MP0000604_amyloidosis2.58090063
6MP0003635_abnormal_synaptic_transmissio2.54544732
7MP0000920_abnormal_myelination2.51308594
8MP0003787_abnormal_imprinting2.49511528
9MP0002139_abnormal_hepatobiliary_system2.44920818
10MP0003303_peritoneal_inflammation2.42477505
11MP0003690_abnormal_glial_cell2.37712519
12MP0005423_abnormal_somatic_nervous2.32939314
13MP0002063_abnormal_learning/memory/cond2.24620811
14MP0003122_maternal_imprinting2.21658615
15MP0000778_abnormal_nervous_system2.20305378
16MP0002734_abnormal_mechanical_nocicepti2.10719004
17MP0005646_abnormal_pituitary_gland2.08273465
18MP0002064_seizures2.07774254
19MP0000569_abnormal_digit_pigmentation2.04550705
20MP0001984_abnormal_olfaction2.01521490
21MP0009745_abnormal_behavioral_response2.00999570
22MP0005360_urolithiasis1.97435787
23MP0009046_muscle_twitch1.97053218
24MP0009780_abnormal_chondrocyte_physiolo1.87465383
25MP0002735_abnormal_chemical_nociception1.84105423
26MP0002572_abnormal_emotion/affect_behav1.83070747
27MP0001486_abnormal_startle_reflex1.81526218
28MP0001968_abnormal_touch/_nociception1.81366062
29MP0002733_abnormal_thermal_nociception1.76718591
30MP0005058_abnormal_lysosome_morphology1.74663566
31MP0001440_abnormal_grooming_behavior1.74300493
32MP0003879_abnormal_hair_cell1.64567642
33MP0003634_abnormal_glial_cell1.64304557
34MP0004742_abnormal_vestibular_system1.62386671
35MP0004885_abnormal_endolymph1.60824766
36MP0005365_abnormal_bile_salt1.60181745
37MP0002272_abnormal_nervous_system1.57187841
38MP0003123_paternal_imprinting1.55536396
39MP0005085_abnormal_gallbladder_physiolo1.53645817
40MP0008875_abnormal_xenobiotic_pharmacok1.51007708
41MP0004510_myositis1.50852043
42MP0006082_CNS_inflammation1.48533318
43MP0003172_abnormal_lysosome_physiology1.46938528
44MP0001970_abnormal_pain_threshold1.43998200
45MP0004858_abnormal_nervous_system1.41126974
46MP0002184_abnormal_innervation1.40776511
47MP0001501_abnormal_sleep_pattern1.38614265
48MP0005551_abnormal_eye_electrophysiolog1.38232239
49MP0003195_calcinosis1.37630982
50MP0002067_abnormal_sensory_capabilities1.33342167
51MP0005386_behavior/neurological_phenoty1.33041516
52MP0004924_abnormal_behavior1.33041516
53MP0003632_abnormal_nervous_system1.32977125
54MP0003121_genomic_imprinting1.32696968
55MP0004811_abnormal_neuron_physiology1.30111330
56MP0002736_abnormal_nociception_after1.29657367
57MP0005083_abnormal_biliary_tract1.29498519
58MP0009840_abnormal_foam_cell1.27868713
59MP0003633_abnormal_nervous_system1.27805409
60MP0001529_abnormal_vocalization1.27305181
61MP0008877_abnormal_DNA_methylation1.24544692
62MP0000955_abnormal_spinal_cord1.24365625
63MP0002090_abnormal_vision1.24171005
64MP0003631_nervous_system_phenotype1.23045042
65MP0003075_altered_response_to1.22345143
66MP0002229_neurodegeneration1.19980448
67MP0006276_abnormal_autonomic_nervous1.19379060
68MP0010386_abnormal_urinary_bladder1.18762815
69MP0010329_abnormal_lipoprotein_level1.18356949
70MP0002557_abnormal_social/conspecific_i1.18177957
71MP0002138_abnormal_hepatobiliary_system1.15937152
72MP0005645_abnormal_hypothalamus_physiol1.14747513
73MP0002882_abnormal_neuron_morphology1.12882927
74MP0004130_abnormal_muscle_cell1.10179902
75MP0003191_abnormal_cellular_cholesterol1.09403484
76MP0002066_abnormal_motor_capabilities/c1.05483200
77MP0002118_abnormal_lipid_homeostasis1.04298017
78MP0002909_abnormal_adrenal_gland1.01891405
79MP0003183_abnormal_peptide_metabolism1.01815954
80MP0003252_abnormal_bile_duct1.01619122
81MP0001502_abnormal_circadian_rhythm0.96435716
82MP0005187_abnormal_penis_morphology0.95781376
83MP0005535_abnormal_body_temperature0.95763260
84MP0008260_abnormal_autophagy0.94759062
85MP0002254_reproductive_system_inflammat0.91898258
86MP0000383_abnormal_hair_follicle0.91624344
87MP0005166_decreased_susceptibility_to0.89961889
88MP0001348_abnormal_lacrimal_gland0.87325597
89MP0002876_abnormal_thyroid_physiology0.87151146
90MP0001485_abnormal_pinna_reflex0.86627856
91MP0010234_abnormal_vibrissa_follicle0.86361040
92MP0010678_abnormal_skin_adnexa0.85724402
93MP0000427_abnormal_hair_cycle0.83738197
94MP0002638_abnormal_pupillary_reflex0.82762003
95MP0002419_abnormal_innate_immunity0.82703395
96MP0001905_abnormal_dopamine_level0.82574865
97MP0005310_abnormal_salivary_gland0.82424500
98MP0008569_lethality_at_weaning0.82237203
99MP0001986_abnormal_taste_sensitivity0.81813161
100MP0000631_abnormal_neuroendocrine_gland0.81247769
101MP0001666_abnormal_nutrient_absorption0.79395270
102MP0005248_abnormal_Harderian_gland0.79346670
103MP0002752_abnormal_somatic_nervous0.78943387
104MP0005451_abnormal_body_composition0.77324954
105MP0004142_abnormal_muscle_tone0.76495427
106MP0001188_hyperpigmentation0.76162707
107MP0000579_abnormal_nail_morphology0.75767026
108MP0008874_decreased_physiological_sensi0.74834833
109MP0009764_decreased_sensitivity_to0.73467045
110MP0000647_abnormal_sebaceous_gland0.73373689
111MP0003868_abnormal_feces_composition0.73219047
112MP0002069_abnormal_eating/drinking_beha0.73002019
113MP0004043_abnormal_pH_regulation0.72660776
114MP0003656_abnormal_erythrocyte_physiolo0.72155586
115MP0008872_abnormal_physiological_respon0.69577875
116MP0000566_synostosis0.69391200
117MP0001963_abnormal_hearing_physiology0.69327738
118MP0001177_atelectasis0.69171263
119MP0002152_abnormal_brain_morphology0.68717457
120MP0002822_catalepsy0.68156384
121MP0002148_abnormal_hypersensitivity_rea0.67302816
122MP0005584_abnormal_enzyme/coenzyme_acti0.66112686
123MP0005253_abnormal_eye_physiology0.64704234
124MP0000639_abnormal_adrenal_gland0.60964435
125MP0005167_abnormal_blood-brain_barrier0.60519459
126MP0001299_abnormal_eye_distance/0.60294985
127MP0003938_abnormal_ear_development0.58612010
128MP0003861_abnormal_nervous_system0.55930254
129MP0005379_endocrine/exocrine_gland_phen0.55199892

Predicted human phenotypes

RankGene SetZ-score
1Neurofibrillary tangles (HP:0002185)5.52440963
2Cerebral inclusion bodies (HP:0100314)4.77274532
3Supranuclear gaze palsy (HP:0000605)4.69785670
4Febrile seizures (HP:0002373)4.29815385
5Mutism (HP:0002300)4.18165781
6Termporal pattern (HP:0011008)3.98182839
7Insidious onset (HP:0003587)3.98182839
8Atonic seizures (HP:0010819)3.96487396
9Abnormality of the corticospinal tract (HP:0002492)3.95710428
10Akinesia (HP:0002304)3.53026321
11Myokymia (HP:0002411)3.32182170
12Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)3.28384748
13Degeneration of the lateral corticospinal tracts (HP:0002314)3.28384748
14Disinhibition (HP:0000734)3.27287986
15Recurrent gram-negative bacterial infections (HP:0005420)3.19927831
16Ankle clonus (HP:0011448)3.19817300
17Increased cerebral lipofuscin (HP:0011813)3.11232185
18Epidermoid cyst (HP:0200040)2.96693201
19Absence seizures (HP:0002121)2.94157096
20Onion bulb formation (HP:0003383)2.93451386
21Action tremor (HP:0002345)2.92623285
22Segmental peripheral demyelination/remyelination (HP:0003481)2.90707363
23Spastic tetraparesis (HP:0001285)2.89564736
24Limb dystonia (HP:0002451)2.83043988
25Inappropriate behavior (HP:0000719)2.80859512
26Axonal loss (HP:0003447)2.78935548
27Drooling (HP:0002307)2.78458273
28Excessive salivation (HP:0003781)2.78458273
29Focal motor seizures (HP:0011153)2.73556313
30Neuronal loss in central nervous system (HP:0002529)2.71914016
31Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.70350662
32Ulnar claw (HP:0001178)2.67783764
33Apathy (HP:0000741)2.66652730
34Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)2.65964871
35Spastic gait (HP:0002064)2.65896630
36Focal seizures (HP:0007359)2.63612955
37Status epilepticus (HP:0002133)2.63216392
38Visual hallucinations (HP:0002367)2.63091923
39Impaired vibration sensation in the lower limbs (HP:0002166)2.61337408
40Peripheral demyelination (HP:0011096)2.59975878
41Increased neuronal autofluorescent lipopigment (HP:0002074)2.58355526
42Hemiparesis (HP:0001269)2.56864315
43Amyotrophic lateral sclerosis (HP:0007354)2.56464401
44Hyperventilation (HP:0002883)2.54282352
45Morphological abnormality of the pyramidal tract (HP:0002062)2.52233814
46Polyphagia (HP:0002591)2.51625422
47Gaze-evoked nystagmus (HP:0000640)2.48432100
48Peripheral hypomyelination (HP:0007182)2.47456486
49Progressive inability to walk (HP:0002505)2.44770695
50Scanning speech (HP:0002168)2.40045794
51Truncal ataxia (HP:0002078)2.39515992
52Abnormality of aromatic amino acid family metabolism (HP:0004338)2.38501364
53Dysdiadochokinesis (HP:0002075)2.36798597
54Diminished motivation (HP:0000745)2.36486824
55Epileptic encephalopathy (HP:0200134)2.36139443
56Deep venous thrombosis (HP:0002625)2.35368883
57Increased circulating renin level (HP:0000848)2.33788145
58Systemic lupus erythematosus (HP:0002725)2.29924808
59Intrahepatic cholestasis (HP:0001406)2.28389315
60Pheochromocytoma (HP:0002666)2.26111832
61Urinary bladder sphincter dysfunction (HP:0002839)2.25143395
62Intention tremor (HP:0002080)2.24122330
63Torticollis (HP:0000473)2.24112032
64Cerebral hypomyelination (HP:0006808)2.22499514
65Agitation (HP:0000713)2.21647380
66Postural instability (HP:0002172)2.21028233
67Eczematoid dermatitis (HP:0000976)2.20480517
68Delusions (HP:0000746)2.18438068
69Xanthomatosis (HP:0000991)2.18315199
70Loss of speech (HP:0002371)2.18205794
71Generalized tonic-clonic seizures (HP:0002069)2.18105138
72Complement deficiency (HP:0004431)2.18073941
73Recurrent bacterial skin infections (HP:0005406)2.17105707
74Urinary urgency (HP:0000012)2.16508659
75Abnormality of glycosphingolipid metabolism (HP:0004343)2.16491955
76Abnormality of glycolipid metabolism (HP:0010969)2.16491955
77Abnormality of liposaccharide metabolism (HP:0010968)2.16491955
78Abnormality of binocular vision (HP:0011514)2.15878755
79Diplopia (HP:0000651)2.15878755
80Broad-based gait (HP:0002136)2.15730985
81Muscular hypotonia of the trunk (HP:0008936)2.14935224
82Anxiety (HP:0000739)2.14781371
83Dysostosis multiplex (HP:0000943)2.14299161
84Depression (HP:0000716)2.13749457
85Clumsiness (HP:0002312)2.11014759
86Papillary thyroid carcinoma (HP:0002895)2.10669948
87Gait imbalance (HP:0002141)2.10385443
88Slow saccadic eye movements (HP:0000514)2.10152519
89Spastic tetraplegia (HP:0002510)2.09245266
90Papilledema (HP:0001085)2.08026111
91Lower limb muscle weakness (HP:0007340)2.06389362
92Dysmetria (HP:0001310)2.06134663
93Amblyopia (HP:0000646)2.04404403
94Poor eye contact (HP:0000817)2.03736427
95Progressive cerebellar ataxia (HP:0002073)2.03659343
96Vacuolated lymphocytes (HP:0001922)2.02485506
97Parakeratosis (HP:0001036)2.01839464
98Amyloidosis (HP:0011034)2.01621673
99Cortical dysplasia (HP:0002539)2.01457155
100Abnormality of salivation (HP:0100755)1.99830988
101Impaired vibratory sensation (HP:0002495)1.99203154
102Generalized myoclonic seizures (HP:0002123)1.98866228
103Pachygyria (HP:0001302)1.98308368
104Retinal atrophy (HP:0001105)1.96798145
105Decreased motor nerve conduction velocity (HP:0003431)1.96476636
106Recurrent abscess formation (HP:0002722)1.93999522
107Neuroendocrine neoplasm (HP:0100634)1.92629144
108Hyperlipoproteinemia (HP:0010980)1.92306558
109Abnormality of macrophages (HP:0004311)1.90673191
110Abnormal eating behavior (HP:0100738)1.90095162
111Postural tremor (HP:0002174)1.90074300
112EEG with generalized epileptiform discharges (HP:0011198)1.89299465
113Hypsarrhythmia (HP:0002521)1.88924362
114Paraplegia (HP:0010550)1.88660579
115Abnormality of the periventricular white matter (HP:0002518)1.88091814
116Macroorchidism (HP:0000053)1.86565147
117Focal dystonia (HP:0004373)1.85640798
118Prolonged partial thromboplastin time (HP:0003645)1.85526921
119Bradykinesia (HP:0002067)1.85482569
120Diminished movement (HP:0002374)1.84978519
121Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.84687401
122Split foot (HP:0001839)1.84472287
123Epileptiform EEG discharges (HP:0011182)1.84332980
124Cerebral hemorrhage (HP:0001342)1.84099752
125Choreoathetosis (HP:0001266)1.83699361
126Dialeptic seizures (HP:0011146)1.83400617
127Craniofacial dystonia (HP:0012179)1.83149611
128Clonus (HP:0002169)1.81359353
129Hypoplasia of the corpus callosum (HP:0002079)1.79580403
130Abnormal social behavior (HP:0012433)1.79393944
131Impaired social interactions (HP:0000735)1.79393944
132Alacrima (HP:0000522)1.79386458
133Hepatoblastoma (HP:0002884)1.78804023
134Mucopolysacchariduria (HP:0008155)1.78204720
135Urinary glycosaminoglycan excretion (HP:0003541)1.78204720
136Absent speech (HP:0001344)1.78120521
137Hammertoe (HP:0001765)1.77784542
138Tetraplegia (HP:0002445)1.75077736
139Dyskinesia (HP:0100660)1.72104664
140Spastic paraplegia (HP:0001258)1.68224964
141Gait ataxia (HP:0002066)1.68135908
142Abnormality of ocular smooth pursuit (HP:0000617)1.65529502
143Impaired smooth pursuit (HP:0007772)1.64266921
144Sleep apnea (HP:0010535)1.63320576
145Abnormality of the lower motor neuron (HP:0002366)1.62796565

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK16.23135916
2MAP3K92.66162261
3DAPK22.22856256
4STK392.18663830
5PKN12.14103751
6DYRK22.07599269
7MAP3K41.91982094
8CASK1.82969459
9NTRK21.76917356
10PRKD31.72589558
11RIPK41.70711760
12FGR1.65960387
13SIK21.63119540
14NTRK31.62710434
15PHKG21.59002885
16PHKG11.59002885
17MINK11.57488728
18EPHA41.57171933
19PAK61.50363307
20EPHB11.48146223
21MAPK131.46602115
22OXSR11.41311864
23MAP4K21.40527309
24NTRK11.40043237
25PBK1.38534203
26MAP2K71.36131032
27CSNK1G21.34549518
28MAP3K21.32977644
29KSR21.31780666
30TAOK31.27459717
31BLK1.25375780
32CDK51.22267039
33MAP2K41.21210629
34LIMK11.20787443
35PINK11.18007087
36SGK21.16605841
37ERBB41.16219147
38WNK31.15559359
39BCR1.11746460
40MAP3K141.10588720
41TRIM281.09971268
42ERBB31.09956646
43MST1R1.04261421
44CSNK1A1L1.03567316
45PRPF4B1.03352241
46LMTK21.02739935
47PLK21.01915200
48MARK20.97251187
49RET0.97233575
50CAMK1G0.96997301
51CSNK1G30.95406578
52CAMKK10.92206967
53ABL20.90454793
54PRKCZ0.90124297
55DAPK10.88350406
56INSRR0.86241082
57NEK60.85521747
58PAK30.85063840
59UHMK10.84957875
60SGK4940.83766608
61SGK2230.83766608
62PRKCE0.83639754
63BMPR1B0.83597029
64MAP3K130.82899407
65CAMK10.81961788
66SGK30.81191475
67STK380.80084808
68LATS20.79998926
69CAMK2A0.79797796
70CAMK2B0.78413124
71FYN0.78067388
72WNK40.77349346
73MET0.76196964
74CDK11A0.72699849
75GRK50.71853596
76FGFR20.70183870
77FES0.68146429
78KSR10.67926592
79MAPK100.67848344
80DYRK1A0.67041758
81MAP3K60.66653819
82STK110.66580051
83TYRO30.66076861
84CSNK1G10.65551152
85BMPR20.65475258
86AKT30.64067865
87RPS6KA20.63604557
88PDPK10.61485277
89YES10.60385196
90PNCK0.59570935
91ROCK20.58955147
92STK38L0.58936772
93FER0.58644720
94MAP3K120.58527118
95SGK10.57337716
96TBK10.56789599
97CDK140.56531497
98CAMK40.56439321
99CSNK1A10.55867431
100GSK3A0.55099899
101PRKCG0.54831144
102PRKCH0.54020794
103BMX0.52364073
104RIPK10.52255158
105PRKCQ0.51948241
106CSNK1D0.51791022
107WNK10.51705120
108CSNK1E0.51609228
109RPS6KA30.51591821
110FRK0.48467620
111CDK190.48397301
112ALK0.48185744
113CAMK1D0.47776426
114CAMKK20.47614318
115EGFR0.44518883
116PIK3CA0.44287729
117CAMK2G0.44165280
118CDK150.43066246
119RPS6KB10.42928113
120MST40.42309353
121JAK20.42019166
122MAPK120.41834229
123CAMK2D0.41565641
124TNIK0.40879619
125JAK10.40877810
126CDK180.40614708
127ERBB20.40490816
128CCNB10.40123215
129PRKACB0.39806309
130PRKG10.39306013
131MAPKAPK50.39305574
132PDK10.39221965
133DAPK30.39160144

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.28940901
2Steroid biosynthesis_Homo sapiens_hsa001002.24284505
3Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.95338397
4Synaptic vesicle cycle_Homo sapiens_hsa047211.91932598
5Vitamin B6 metabolism_Homo sapiens_hsa007501.77992243
6Nitrogen metabolism_Homo sapiens_hsa009101.63915932
7Nicotine addiction_Homo sapiens_hsa050331.61676170
8GABAergic synapse_Homo sapiens_hsa047271.58134871
9Primary bile acid biosynthesis_Homo sapiens_hsa001201.52576159
10Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.52379432
11Staphylococcus aureus infection_Homo sapiens_hsa051501.50207689
12Collecting duct acid secretion_Homo sapiens_hsa049661.46270787
13Butanoate metabolism_Homo sapiens_hsa006501.43286742
14Axon guidance_Homo sapiens_hsa043601.41628976
15Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.40398566
16Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.39939227
17Glutamatergic synapse_Homo sapiens_hsa047241.32853531
18Morphine addiction_Homo sapiens_hsa050321.28536131
19Phagosome_Homo sapiens_hsa041451.26468597
20Circadian rhythm_Homo sapiens_hsa047101.20039783
21Complement and coagulation cascades_Homo sapiens_hsa046101.19537271
22Lysosome_Homo sapiens_hsa041421.19215233
23Circadian entrainment_Homo sapiens_hsa047131.18170287
24Histidine metabolism_Homo sapiens_hsa003401.17674270
25Maturity onset diabetes of the young_Homo sapiens_hsa049501.15752497
26Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.14880212
27Arginine biosynthesis_Homo sapiens_hsa002201.11964242
28Dopaminergic synapse_Homo sapiens_hsa047281.09781094
29Type II diabetes mellitus_Homo sapiens_hsa049301.08792031
30Cocaine addiction_Homo sapiens_hsa050301.08453981
31Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.04497484
32Fatty acid elongation_Homo sapiens_hsa000621.04216576
33Cholinergic synapse_Homo sapiens_hsa047251.03963472
34Vibrio cholerae infection_Homo sapiens_hsa051101.01485918
35Serotonergic synapse_Homo sapiens_hsa047261.01342263
36Rheumatoid arthritis_Homo sapiens_hsa053231.01139685
37Prion diseases_Homo sapiens_hsa050201.00279774
38Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.99204334
39Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.97618189
40Pancreatic secretion_Homo sapiens_hsa049720.94765950
41Long-term depression_Homo sapiens_hsa047300.93462775
42Phosphatidylinositol signaling system_Homo sapiens_hsa040700.93432847
43Renin secretion_Homo sapiens_hsa049240.90792545
44Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.89744510
45Phototransduction_Homo sapiens_hsa047440.89639301
46Olfactory transduction_Homo sapiens_hsa047400.87235574
47Ether lipid metabolism_Homo sapiens_hsa005650.86439997
48Long-term potentiation_Homo sapiens_hsa047200.85559587
49Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.84160770
50Regulation of autophagy_Homo sapiens_hsa041400.84030304
51Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.83736182
52Thyroid hormone synthesis_Homo sapiens_hsa049180.83684325
53Salivary secretion_Homo sapiens_hsa049700.83489946
54Arginine and proline metabolism_Homo sapiens_hsa003300.82624885
55Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.82378965
56Bile secretion_Homo sapiens_hsa049760.82183741
57Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.82131587
58Pertussis_Homo sapiens_hsa051330.81936064
59Mineral absorption_Homo sapiens_hsa049780.81851156
60Oocyte meiosis_Homo sapiens_hsa041140.80443048
61ErbB signaling pathway_Homo sapiens_hsa040120.79567429
62Gastric acid secretion_Homo sapiens_hsa049710.79384198
63Calcium signaling pathway_Homo sapiens_hsa040200.79383541
64Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.78645367
65Sulfur metabolism_Homo sapiens_hsa009200.76977373
66Dorso-ventral axis formation_Homo sapiens_hsa043200.74446051
67Tuberculosis_Homo sapiens_hsa051520.74253402
68ABC transporters_Homo sapiens_hsa020100.72483079
69Amphetamine addiction_Homo sapiens_hsa050310.72155217
70Sphingolipid metabolism_Homo sapiens_hsa006000.70128232
71Insulin secretion_Homo sapiens_hsa049110.69579783
72Chemokine signaling pathway_Homo sapiens_hsa040620.68541609
73Salmonella infection_Homo sapiens_hsa051320.68502251
74Renal cell carcinoma_Homo sapiens_hsa052110.68439482
75PPAR signaling pathway_Homo sapiens_hsa033200.67755723
76Tryptophan metabolism_Homo sapiens_hsa003800.67100699
77Sphingolipid signaling pathway_Homo sapiens_hsa040710.66334015
78Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.65727014
79Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.65619212
80Toll-like receptor signaling pathway_Homo sapiens_hsa046200.65494175
81Aldosterone synthesis and secretion_Homo sapiens_hsa049250.64492199
82Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.63832305
83Estrogen signaling pathway_Homo sapiens_hsa049150.62791300
84cGMP-PKG signaling pathway_Homo sapiens_hsa040220.60594386
85Protein export_Homo sapiens_hsa030600.60395557
86Gap junction_Homo sapiens_hsa045400.59976258
87Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.59874778
88Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.59280549
89GnRH signaling pathway_Homo sapiens_hsa049120.58627056
90Taste transduction_Homo sapiens_hsa047420.58484938
91Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.58258609
92Amoebiasis_Homo sapiens_hsa051460.58091994
93Osteoclast differentiation_Homo sapiens_hsa043800.57951219
94Fatty acid biosynthesis_Homo sapiens_hsa000610.57245559
95Endocytosis_Homo sapiens_hsa041440.56992282
96Caffeine metabolism_Homo sapiens_hsa002320.56406037
97Inositol phosphate metabolism_Homo sapiens_hsa005620.56345259
98Fatty acid metabolism_Homo sapiens_hsa012120.55726868
99Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.55547229
100Steroid hormone biosynthesis_Homo sapiens_hsa001400.55472854
101Oxytocin signaling pathway_Homo sapiens_hsa049210.54990341
102Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.53952217
103Glucagon signaling pathway_Homo sapiens_hsa049220.51396962
104Melanogenesis_Homo sapiens_hsa049160.50473189
105Tight junction_Homo sapiens_hsa045300.49186123
106Phospholipase D signaling pathway_Homo sapiens_hsa040720.48803677
107Graft-versus-host disease_Homo sapiens_hsa053320.48792983
108Leishmaniasis_Homo sapiens_hsa051400.48376163
109Type I diabetes mellitus_Homo sapiens_hsa049400.48184794
110Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.47989967
111African trypanosomiasis_Homo sapiens_hsa051430.47730190
112Carbohydrate digestion and absorption_Homo sapiens_hsa049730.47145354
113cAMP signaling pathway_Homo sapiens_hsa040240.47116772
114Peroxisome_Homo sapiens_hsa041460.46715786
115AMPK signaling pathway_Homo sapiens_hsa041520.46215722
116Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.45417674
117Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.45348687
118Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.45026454
119Fat digestion and absorption_Homo sapiens_hsa049750.44965526
120beta-Alanine metabolism_Homo sapiens_hsa004100.44882504
121Ras signaling pathway_Homo sapiens_hsa040140.44727319
122Glioma_Homo sapiens_hsa052140.44576737
123Pentose and glucuronate interconversions_Homo sapiens_hsa000400.41922296
124Ovarian steroidogenesis_Homo sapiens_hsa049130.41572720
125Endometrial cancer_Homo sapiens_hsa052130.41416963
126mTOR signaling pathway_Homo sapiens_hsa041500.40930707
127Rap1 signaling pathway_Homo sapiens_hsa040150.38766562
128Folate biosynthesis_Homo sapiens_hsa007900.38461380
129Propanoate metabolism_Homo sapiens_hsa006400.38117522
130Phenylalanine metabolism_Homo sapiens_hsa003600.33827018

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