SIDT1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative regulation of leukocyte mediated cytotoxicity (GO:0001911)7.96155164
2negative regulation of cell killing (GO:0031342)7.96155164
3negative T cell selection (GO:0043383)5.27743740
4antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G5.17567980
5positive T cell selection (GO:0043368)5.15302850
6negative thymic T cell selection (GO:0045060)4.96393384
7regulation of short-term neuronal synaptic plasticity (GO:0048172)4.87785411
8antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.72887978
9cellular response to interleukin-15 (GO:0071350)4.68348931
10response to interleukin-15 (GO:0070672)4.64723997
11positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.64340909
12regulation of isotype switching to IgG isotypes (GO:0048302)4.57465214
13ionotropic glutamate receptor signaling pathway (GO:0035235)4.57354435
14antigen processing and presentation of endogenous antigen (GO:0019883)4.56865657
15interferon-gamma production (GO:0032609)4.43656572
16vocalization behavior (GO:0071625)4.43317316
17regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.40753236
18T cell selection (GO:0045058)4.37422966
19positive thymic T cell selection (GO:0045059)4.36663247
20antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.33551175
21thymic T cell selection (GO:0045061)4.29548443
22positive regulation of gamma-delta T cell activation (GO:0046645)4.28497595
23B cell receptor signaling pathway (GO:0050853)4.24006925
24positive regulation of granulocyte differentiation (GO:0030854)4.23633199
25locomotory exploration behavior (GO:0035641)4.23482547
26glutamate secretion (GO:0014047)4.21991145
27glutamate receptor signaling pathway (GO:0007215)4.16325478
28synaptic vesicle exocytosis (GO:0016079)4.16170009
29regulation of glutamate receptor signaling pathway (GO:1900449)4.15161190
30positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)4.10708307
31synaptic vesicle maturation (GO:0016188)4.06820045
32synaptic vesicle docking involved in exocytosis (GO:0016081)4.05745809
33activated T cell proliferation (GO:0050798)3.98615025
34cellular potassium ion homeostasis (GO:0030007)3.94950404
35regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.91017563
36negative regulation of T cell mediated immunity (GO:0002710)3.88368553
37regulation of synaptic vesicle exocytosis (GO:2000300)3.87053153
38synaptic transmission, glutamatergic (GO:0035249)3.83955278
39protein localization to synapse (GO:0035418)3.76251996
40positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.73369674
41neuronal action potential propagation (GO:0019227)3.73290060
42gamma-aminobutyric acid signaling pathway (GO:0007214)3.71321781
43hepatocyte apoptotic process (GO:0097284)3.65666369
44neuron cell-cell adhesion (GO:0007158)3.60978997
45response to type I interferon (GO:0034340)3.60660217
46long-term memory (GO:0007616)3.59871598
47type I interferon signaling pathway (GO:0060337)3.58419302
48cellular response to type I interferon (GO:0071357)3.58419302
49regulation of alpha-beta T cell proliferation (GO:0046640)3.57477819
50T cell receptor signaling pathway (GO:0050852)3.55930925
51regulation of gamma-delta T cell differentiation (GO:0045586)3.55579048
52leukocyte aggregation (GO:0070486)3.55495045
53T cell migration (GO:0072678)3.53779534
54regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.53779509
55neuron-neuron synaptic transmission (GO:0007270)3.51891545
56regulation of synaptic vesicle transport (GO:1902803)3.51241242
57sodium ion export (GO:0071436)3.50802985
58cerebellar Purkinje cell differentiation (GO:0021702)3.49679832
59regulation of long-term neuronal synaptic plasticity (GO:0048169)3.48104073
60regulation of T cell mediated cytotoxicity (GO:0001914)3.43870255
61G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.40780504
62long-term synaptic potentiation (GO:0060291)3.39589109
63exploration behavior (GO:0035640)3.38163085
64regulation of neuronal synaptic plasticity (GO:0048168)3.36321016
65regulation of B cell differentiation (GO:0045577)3.31914784
66regulation of excitatory postsynaptic membrane potential (GO:0060079)3.30646878
67regulation of T cell tolerance induction (GO:0002664)3.29912532
68signal complex assembly (GO:0007172)3.29453544
69positive regulation of interleukin-2 biosynthetic process (GO:0045086)3.28467690
70neurotransmitter secretion (GO:0007269)3.23644493
71mast cell activation (GO:0045576)3.23185420
72positive regulation of B cell differentiation (GO:0045579)3.21298926
73positive regulation of T cell mediated cytotoxicity (GO:0001916)3.18366145
74interferon-gamma secretion (GO:0072643)3.17388005
75regulation of regulatory T cell differentiation (GO:0045589)3.17291414
76G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.15839129
77CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)3.15562189
78regulation of B cell receptor signaling pathway (GO:0050855)3.14987938
79glycosphingolipid biosynthetic process (GO:0006688)3.14505788
80regulation of postsynaptic membrane potential (GO:0060078)3.13688728
81regulation of gamma-delta T cell activation (GO:0046643)3.13242633
82positive regulation of membrane potential (GO:0045838)3.12993131
83regulation of synaptic plasticity (GO:0048167)3.12079206
84negative regulation of lymphocyte mediated immunity (GO:0002707)3.11577584
85modulation by symbiont of host defense response (GO:0052031)3.07283766
86modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.07283766
87modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.07283766
88positive regulation by organism of defense response of other organism involved in symbiotic interact3.07283766
89modulation by symbiont of host immune response (GO:0052553)3.07283766
90positive regulation by symbiont of host defense response (GO:0052509)3.07283766
91positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.06854538
92regulation of leukocyte mediated cytotoxicity (GO:0001910)3.05768920
93immunoglobulin mediated immune response (GO:0016064)3.04245488
94positive regulation of alpha-beta T cell proliferation (GO:0046641)3.03709871
95negative regulation of synaptic transmission, GABAergic (GO:0032229)3.02362920
96positive regulation of synapse maturation (GO:0090129)3.02011270
97regulation of ARF protein signal transduction (GO:0032012)3.01709322
98neurotransmitter-gated ion channel clustering (GO:0072578)3.00303331
99response to histamine (GO:0034776)2.99551646
100regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370)2.97092445
101regulation of cell killing (GO:0031341)2.96964381
102positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.96391978
103interferon-gamma-mediated signaling pathway (GO:0060333)2.95840033
104phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.95327467
105regulation of CD4-positive, alpha-beta T cell activation (GO:2000514)2.94837624
106negative regulation of leukocyte mediated immunity (GO:0002704)2.94603023
107negative regulation of adaptive immune response based on somatic recombination of immune receptors b2.94489228
108B cell homeostasis (GO:0001782)2.94176859
109gamma-aminobutyric acid transport (GO:0015812)2.93216627
110positive regulation of leukocyte mediated cytotoxicity (GO:0001912)2.92710968
111T cell costimulation (GO:0031295)2.91690091
112antigen receptor-mediated signaling pathway (GO:0050851)2.89673452
113presynaptic membrane assembly (GO:0097105)2.88300198
114regulation of alpha-beta T cell activation (GO:0046634)2.86866215
115lymphocyte costimulation (GO:0031294)2.86239047
116regulation of granulocyte differentiation (GO:0030852)2.86168071
117positive regulation of cell killing (GO:0031343)2.84331303
118positive regulation of interleukin-4 production (GO:0032753)2.84216212
119positive regulation of neurotransmitter secretion (GO:0001956)2.83364629
120mast cell activation involved in immune response (GO:0002279)2.82572571
121mast cell degranulation (GO:0043303)2.82572571
122CD4-positive, alpha-beta T cell differentiation involved in immune response (GO:0002294)2.82504403
123T-helper cell differentiation (GO:0042093)2.82504403
124negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.80365474
125lymphocyte migration (GO:0072676)2.77735174
126regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.77474943
127synaptic vesicle endocytosis (GO:0048488)2.76071558
128regulation of Rap GTPase activity (GO:0032317)2.76026422
129negative regulation of B cell proliferation (GO:0030889)2.75848809
130proline transport (GO:0015824)2.75466878
131regulation of dendritic spine morphogenesis (GO:0061001)2.73417896
132negative regulation of adaptive immune response (GO:0002820)2.73378795
133negative regulation of T-helper cell differentiation (GO:0045623)2.73346206
134negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.73346206
135activation of protein kinase A activity (GO:0034199)2.72500899
136defense response to protozoan (GO:0042832)2.71866554
137protein targeting to Golgi (GO:0000042)2.71225695
138alpha-beta T cell differentiation (GO:0046632)2.68867131
139negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.68585858
140positive regulation of interleukin-2 production (GO:0032743)2.68111547
141negative regulation of alpha-beta T cell activation (GO:0046636)2.68082890
142regulation of B cell proliferation (GO:0030888)2.67806275
143positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372)2.66624978
144regulation of interleukin-4 production (GO:0032673)2.66196858
145behavioral defense response (GO:0002209)2.64979400
146behavioral fear response (GO:0001662)2.64979400
147regulation of synaptic transmission, glutamatergic (GO:0051966)2.64813541
148regulation of T cell mediated immunity (GO:0002709)2.64780451
149cytidine metabolic process (GO:0046087)2.64656665
150cytidine catabolic process (GO:0006216)2.64656665
151cytidine deamination (GO:0009972)2.64656665
152transmission of nerve impulse (GO:0019226)2.63521881
153regulation of alpha-beta T cell differentiation (GO:0046637)2.63521462
154alpha-beta T cell activation (GO:0046631)2.63430951
155regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.62357569
156positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516)2.62336451
157neuron recognition (GO:0008038)2.60951526
158establishment of protein localization to Golgi (GO:0072600)2.59983847
159positive regulation of humoral immune response (GO:0002922)2.58665744
160regulation of neurotransmitter secretion (GO:0046928)2.58012752
161presynaptic membrane organization (GO:0097090)2.58004025
162regulation of natural killer cell mediated immunity (GO:0002715)2.57138433
163regulation of natural killer cell mediated cytotoxicity (GO:0042269)2.57138433
164positive regulation of tolerance induction (GO:0002645)2.56917389
165tolerance induction (GO:0002507)2.56658134
166regulation of T cell receptor signaling pathway (GO:0050856)2.55502405

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human5.92027448
2EZH2_22144423_ChIP-Seq_EOC_Human5.18832246
3FOXP3_17237761_ChIP-ChIP_TREG_Mouse4.04206616
4STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.92335325
5GBX2_23144817_ChIP-Seq_PC3_Human3.01883044
6IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.98078083
7IRF8_21731497_ChIP-ChIP_J774_Mouse2.84705675
8IKZF1_21737484_ChIP-ChIP_HCT116_Human2.54818807
9DROSHA_22980978_ChIP-Seq_HELA_Human2.52884237
10* JARID2_20064375_ChIP-Seq_MESCs_Mouse2.46485021
11* SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.44782336
12SMAD_19615063_ChIP-ChIP_OVARY_Human2.44124086
13RUNX_20019798_ChIP-Seq_JUKART_Human2.41301364
14* SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.40396307
15MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.36679104
16REST_21632747_ChIP-Seq_MESCs_Mouse2.32483683
17RARB_27405468_Chip-Seq_BRAIN_Mouse2.30848093
18VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.20377773
19* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.14448261
20FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse2.10394067
21SCL_19346495_ChIP-Seq_HPC-7_Human2.03956142
22IRF8_27001747_Chip-Seq_BMDM_Mouse2.02143054
23* EZH2_18974828_ChIP-Seq_MESCs_Mouse2.00790035
24* RNF2_18974828_ChIP-Seq_MESCs_Mouse2.00790035
25* MTF2_20144788_ChIP-Seq_MESCs_Mouse1.99099792
26* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.98963006
27AR_21572438_ChIP-Seq_LNCaP_Human1.98924983
28STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.96688406
29ESR1_20079471_ChIP-ChIP_T-47D_Human1.94611256
30SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.90028465
31GATA3_26560356_Chip-Seq_TH2_Human1.87126551
32NOTCH1_21737748_ChIP-Seq_TLL_Human1.85563061
33EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.85460703
34* SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.82633244
35REST_18959480_ChIP-ChIP_MESCs_Mouse1.81761933
36SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.79431116
37LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.79263441
38* JARID2_20075857_ChIP-Seq_MESCs_Mouse1.79183357
39SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.78804117
40SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.72938515
41RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.72311721
42ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.70753345
43* SUZ12_27294783_Chip-Seq_ESCs_Mouse1.70372825
44RNF2_27304074_Chip-Seq_ESCs_Mouse1.68535509
45BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.63480013
46CTBP1_25329375_ChIP-Seq_LNCAP_Human1.60832991
47EZH2_27304074_Chip-Seq_ESCs_Mouse1.57462454
48* EZH2_27294783_Chip-Seq_ESCs_Mouse1.57057784
49TAF15_26573619_Chip-Seq_HEK293_Human1.56748066
50CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.56469612
51SMAD4_21799915_ChIP-Seq_A2780_Human1.55908249
52ER_23166858_ChIP-Seq_MCF-7_Human1.53858008
53MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.47018104
54SPI1_23547873_ChIP-Seq_NB4_Human1.45021789
55ELF1_17652178_ChIP-ChIP_JURKAT_Human1.44776715
56SPI1_23127762_ChIP-Seq_K562_Human1.44378333
57ZFP57_27257070_Chip-Seq_ESCs_Mouse1.40552217
58FLI1_27457419_Chip-Seq_LIVER_Mouse1.40514597
59CTBP2_25329375_ChIP-Seq_LNCAP_Human1.40166139
60* EED_16625203_ChIP-ChIP_MESCs_Mouse1.36204918
61PRDM14_20953172_ChIP-Seq_ESCs_Human1.35772069
62DNAJC2_21179169_ChIP-ChIP_NT2_Human1.34204100
63VDR_24787735_ChIP-Seq_THP-1_Human1.32306041
64MAF_26560356_Chip-Seq_TH2_Human1.31324275
65GATA1_22025678_ChIP-Seq_K562_Human1.30832503
66AR_25329375_ChIP-Seq_VCAP_Human1.30179037
67PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.29617985
68MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.27854978
69KDM2B_26808549_Chip-Seq_SUP-B15_Human1.26540189
70P300_19829295_ChIP-Seq_ESCs_Human1.25350426
71IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.22105838
72* SMRT_27268052_Chip-Seq_Bcells_Human1.21835509
73NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.21680971
74STAT3_23295773_ChIP-Seq_U87_Human1.20933549
75NR3C1_23031785_ChIP-Seq_PC12_Mouse1.20589317
76RUNX1_22412390_ChIP-Seq_EML_Mouse1.19814197
77TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.18472228
78LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.17609543
79* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.17241879
80FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.16362734
81GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.15673586
82SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.15655783
83MYB_26560356_Chip-Seq_TH2_Human1.15187007
84SOX2_21211035_ChIP-Seq_LN229_Gbm1.14486532
85AR_19668381_ChIP-Seq_PC3_Human1.13559283
86RXR_22108803_ChIP-Seq_LS180_Human1.13507005
87* TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.11861297
88IRF1_19129219_ChIP-ChIP_H3396_Human1.11216866
89VDR_24763502_ChIP-Seq_THP-1_Human1.10755426
90RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.10333101
91CIITA_25753668_ChIP-Seq_RAJI_Human1.09873631
92* ARNT_22903824_ChIP-Seq_MCF-7_Human1.09529249
93VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.09235198
94* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.08840386
95GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07262233
96TP53_16413492_ChIP-PET_HCT116_Human1.06764165
97GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.06552878
98PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.05043007
99GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.04834101
100* TCF4_23295773_ChIP-Seq_U87_Human1.04451479
101* KDM2B_26808549_Chip-Seq_DND41_Human1.02597906
102KDM2B_26808549_Chip-Seq_JURKAT_Human1.01759590
103GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.00519298
104PCGF2_27294783_Chip-Seq_ESCs_Mouse1.00507794
105* AHR_22903824_ChIP-Seq_MCF-7_Human1.00251904
106* GATA1_19941827_ChIP-Seq_MEL_Mouse1.00178291
107POU3F2_20337985_ChIP-ChIP_501MEL_Human1.00117220
108RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.98620376
109TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.98545098
110STAT4_19710469_ChIP-ChIP_TH1__Mouse0.97616888
111TOP2B_26459242_ChIP-Seq_MCF-7_Human0.96806052
112POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.96735722
113TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.96735722
114EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.96452258
115ZNF274_21170338_ChIP-Seq_K562_Hela0.96349965
116BCAT_22108803_ChIP-Seq_LS180_Human0.96326534
117SMAD3_21741376_ChIP-Seq_EPCs_Human0.95601187
118SMAD2/3_21741376_ChIP-Seq_EPCs_Human0.94575022
119MYC_22102868_ChIP-Seq_BL_Human0.93043153
120NANOG_18555785_Chip-Seq_ESCs_Mouse0.92882123
121* GATA3_26560356_Chip-Seq_TH1_Human0.92730797
122CTNNB1_20460455_ChIP-Seq_HCT116_Human0.92619263
123SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.92602262
124OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.92478505
125WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.91921015
126MYB_21317192_ChIP-Seq_ERMYB_Mouse0.90844434
127TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.90466928
128NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.89613079
129STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.89515001
130P300_27268052_Chip-Seq_Bcells_Human0.88819660
131EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.88371621
132SMAD3_21741376_ChIP-Seq_HESCs_Human0.88003263
133* GATA3_27048872_Chip-Seq_THYMUS_Human0.87844469
134TCF7_22412390_ChIP-Seq_EML_Mouse0.87733036
135MAF_26560356_Chip-Seq_TH1_Human0.87696189
136P53_22127205_ChIP-Seq_FIBROBLAST_Human0.87561492
137UTX_26944678_Chip-Seq_JUKART_Human0.87522333
138THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.86624654
139WT1_25993318_ChIP-Seq_PODOCYTE_Human0.86621899
140RING1B_27294783_Chip-Seq_ESCs_Mouse0.86476291
141PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.86424419
142PCGF2_27294783_Chip-Seq_NPCs_Mouse0.86148441
143TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.85361193
144E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.85179307
145NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.84836964
146SMAD4_21741376_ChIP-Seq_HESCs_Human0.84755267
147MYB_26560356_Chip-Seq_TH1_Human0.84734157
148PIAS1_25552417_ChIP-Seq_VCAP_Human0.84287068
149YAP1_20516196_ChIP-Seq_MESCs_Mouse0.84113812
150GATA3_21878914_ChIP-Seq_MCF-7_Human0.84074442
151BCL6_27268052_Chip-Seq_Bcells_Human0.83637624
152* TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human0.83070266
153STAT1_20625510_ChIP-Seq_HELA_Human0.82876204
154FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.82161182
155TP53_22573176_ChIP-Seq_HFKS_Human0.80400222
156BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.79247091
157FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.78515801
158Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.78280965
159SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.77160819
160FOXA1_27270436_Chip-Seq_PROSTATE_Human0.76867865
161FOXA1_25329375_ChIP-Seq_VCAP_Human0.76867865
162PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.76590819
163* CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.76206092
164VDR_22108803_ChIP-Seq_LS180_Human0.75751980
165EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.75688085
166PU_27001747_Chip-Seq_BMDM_Mouse0.75448837
167RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.75403812
168FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.74934752
169GATA2_19941826_ChIP-Seq_K562_Human0.74830215

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.63234861
2MP0003880_abnormal_central_pattern4.99938449
3MP0003635_abnormal_synaptic_transmissio3.97844013
4MP0001835_abnormal_antigen_presentation3.51762032
5MP0009745_abnormal_behavioral_response3.37813887
6MP0003763_abnormal_thymus_physiology3.20920993
7MP0002063_abnormal_learning/memory/cond3.06685715
8MP0003724_increased_susceptibility_to3.01436751
9MP0002064_seizures2.99770349
10MP0001968_abnormal_touch/_nociception2.86843813
11MP0004270_analgesia2.80329291
12MP0002572_abnormal_emotion/affect_behav2.68990213
13MP0002822_catalepsy2.55693997
14MP0001501_abnormal_sleep_pattern2.50023247
15MP0002735_abnormal_chemical_nociception2.42589108
16MP0009046_muscle_twitch2.42428366
17MP0005075_abnormal_melanosome_morpholog2.41492899
18MP0002736_abnormal_nociception_after2.32910920
19MP0003787_abnormal_imprinting2.32133233
20MP0002272_abnormal_nervous_system2.30601620
21MP0003436_decreased_susceptibility_to2.30157084
22MP0008569_lethality_at_weaning2.17611059
23MP0005671_abnormal_response_to2.11202031
24MP0009785_altered_susceptibility_to2.07295591
25MP0001486_abnormal_startle_reflex2.06649283
26MP0001440_abnormal_grooming_behavior1.97738598
27MP0003183_abnormal_peptide_metabolism1.95111449
28MP0002734_abnormal_mechanical_nocicepti1.91808699
29MP0005423_abnormal_somatic_nervous1.89953525
30MP0003329_amyloid_beta_deposits1.88579274
31MP0004510_myositis1.83124929
32MP0002419_abnormal_innate_immunity1.78971885
33MP0002148_abnormal_hypersensitivity_rea1.76976550
34MP0002067_abnormal_sensory_capabilities1.74855737
35MP0005464_abnormal_platelet_physiology1.63816675
36MP0001970_abnormal_pain_threshold1.62658138
37MP0009333_abnormal_splenocyte_physiolog1.62482417
38MP0009780_abnormal_chondrocyte_physiolo1.52463739
39MP0001873_stomach_inflammation1.49645539
40MP0001845_abnormal_inflammatory_respons1.48276926
41MP0002733_abnormal_thermal_nociception1.47699248
42MP0008877_abnormal_DNA_methylation1.46396285
43MP0003879_abnormal_hair_cell1.45334021
44MP0008961_abnormal_basal_metabolism1.44066629
45MP0002557_abnormal_social/conspecific_i1.43549373
46MP0004924_abnormal_behavior1.43087374
47MP0005386_behavior/neurological_phenoty1.43087374
48MP0002184_abnormal_innervation1.41568662
49MP0002138_abnormal_hepatobiliary_system1.41273317
50MP0000703_abnormal_thymus_morphology1.34632263
51MP0004811_abnormal_neuron_physiology1.32816718
52MP0003633_abnormal_nervous_system1.31687214
53MP0005310_abnormal_salivary_gland1.31392114
54MP0003866_abnormal_defecation1.30404246
55MP0000685_abnormal_immune_system1.28075659
56MP0003045_fibrosis1.26346050
57MP0002420_abnormal_adaptive_immunity1.25653444
58MP0001800_abnormal_humoral_immune1.25196929
59MP0001819_abnormal_immune_cell1.23340099
60MP0002166_altered_tumor_susceptibility1.22845209
61MP0010234_abnormal_vibrissa_follicle1.22705422
62MP0002693_abnormal_pancreas_physiology1.22309544
63MP0000778_abnormal_nervous_system1.21777330
64MP0008874_decreased_physiological_sensi1.21045180
65MP0002398_abnormal_bone_marrow1.19659100
66MP0003172_abnormal_lysosome_physiology1.19438508
67MP0002006_tumorigenesis1.18877898
68MP0001790_abnormal_immune_system1.18872405
69MP0005387_immune_system_phenotype1.18872405
70MP0001986_abnormal_taste_sensitivity1.18365991
71MP0002723_abnormal_immune_serum1.17161868
72MP0001502_abnormal_circadian_rhythm1.14935528
73MP0000465_gastrointestinal_hemorrhage1.11729395
74MP0001533_abnormal_skeleton_physiology1.09809245
75MP0001905_abnormal_dopamine_level1.08677296
76MP0002066_abnormal_motor_capabilities/c1.08532739
77MP0004484_altered_response_of1.07584829
78MP0005000_abnormal_immune_tolerance1.06652974
79MP0002277_abnormal_respiratory_mucosa1.05150773
80MP0002933_joint_inflammation1.04537406
81MP0005379_endocrine/exocrine_gland_phen1.02398699
82MP0000604_amyloidosis1.02314425
83MP0003631_nervous_system_phenotype1.01256171
84MP0000716_abnormal_immune_system1.01222421
85MP0001663_abnormal_digestive_system1.00777041
86MP0004264_abnormal_extraembryonic_tissu0.99016144
87MP0008872_abnormal_physiological_respon0.96763734
88MP0002928_abnormal_bile_duct0.96474141
89MP0002163_abnormal_gland_morphology0.95400937
90MP0000955_abnormal_spinal_cord0.95013647
91MP0002882_abnormal_neuron_morphology0.93965470
92MP0008469_abnormal_protein_level0.90903923
93MP0010386_abnormal_urinary_bladder0.90150031
94MP0000015_abnormal_ear_pigmentation0.89394523
95MP0001851_eye_inflammation0.89238952
96MP0000427_abnormal_hair_cycle0.89119132
97MP0001984_abnormal_olfaction0.89084316
98MP0002909_abnormal_adrenal_gland0.88688311
99MP0006276_abnormal_autonomic_nervous0.87573727
100MP0005646_abnormal_pituitary_gland0.87399830
101MP0002452_abnormal_antigen_presenting0.87319782
102MP0001919_abnormal_reproductive_system0.85308155
103MP0001765_abnormal_ion_homeostasis0.85215730
104MP0001348_abnormal_lacrimal_gland0.84150344
105MP0004858_abnormal_nervous_system0.84131522
106MP0009764_decreased_sensitivity_to0.84081878
107MP0004142_abnormal_muscle_tone0.83034690
108MP0006082_CNS_inflammation0.81611687
109MP0002722_abnormal_immune_system0.81516417
110MP0002876_abnormal_thyroid_physiology0.80744253
111MP0002009_preneoplasia0.80229669
112MP0000920_abnormal_myelination0.79795519
113MP0008057_abnormal_DNA_replication0.79299794
114MP0005535_abnormal_body_temperature0.78867598
115MP0003300_gastrointestinal_ulcer0.78623625
116MP0004742_abnormal_vestibular_system0.77888962
117MP0002069_abnormal_eating/drinking_beha0.77663467
118MP0002152_abnormal_brain_morphology0.74283223
119MP0004947_skin_inflammation0.74015683
120MP0004043_abnormal_pH_regulation0.73250617
121MP0010155_abnormal_intestine_physiology0.70502944
122MP0002396_abnormal_hematopoietic_system0.69303879
123MP0005551_abnormal_eye_electrophysiolog0.68970879
124MP0000689_abnormal_spleen_morphology0.68657812
125MP0000372_irregular_coat_pigmentation0.68315478
126MP0005174_abnormal_tail_pigmentation0.66257708
127MP0004130_abnormal_muscle_cell0.65697091
128MP0005166_decreased_susceptibility_to0.65086691
129MP0005645_abnormal_hypothalamus_physiol0.64584659
130MP0002429_abnormal_blood_cell0.64109758
131MP0002405_respiratory_system_inflammati0.64092145
132MP0004883_abnormal_blood_vessel0.63869487
133MP0004145_abnormal_muscle_electrophysio0.63704782
134MP0004381_abnormal_hair_follicle0.63577715
135MP0002837_dystrophic_cardiac_calcinosis0.62605526
136MP0003303_peritoneal_inflammation0.60258111
137MP0005025_abnormal_response_to0.60219906
138MP0003195_calcinosis0.60195412
139MP0004885_abnormal_endolymph0.59547085
140MP0000470_abnormal_stomach_morphology0.59270474
141MP0003075_altered_response_to0.58871897
142MP0000569_abnormal_digit_pigmentation0.58445174
143MP0001188_hyperpigmentation0.58098907
144MP0008995_early_reproductive_senescence0.56607236
145MP0000371_diluted_coat_color0.56519990
146MP0002136_abnormal_kidney_physiology0.55873632
147MP0001664_abnormal_digestion0.55811975
148MP0005381_digestive/alimentary_phenotyp0.55635738
149MP0002132_abnormal_respiratory_system0.53476204

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)7.73207730
2Focal seizures (HP:0007359)5.34661148
3Atonic seizures (HP:0010819)5.32597728
4T lymphocytopenia (HP:0005403)5.12548178
5Febrile seizures (HP:0002373)4.94405208
6Abnormality of T cell number (HP:0011839)4.89861663
7Epileptic encephalopathy (HP:0200134)4.64311842
8Visual hallucinations (HP:0002367)4.57631301
9Myokymia (HP:0002411)4.52807538
10Absence seizures (HP:0002121)4.39714067
11Dialeptic seizures (HP:0011146)3.92181394
12Diplopia (HP:0000651)3.75128851
13Abnormality of binocular vision (HP:0011514)3.75128851
14Stomatitis (HP:0010280)3.69353140
15Progressive cerebellar ataxia (HP:0002073)3.64365488
16Hyperventilation (HP:0002883)3.63538534
17Agammaglobulinemia (HP:0004432)3.59783528
18Optic neuritis (HP:0100653)3.58289116
19Retrobulbar optic neuritis (HP:0100654)3.58289116
20Broad-based gait (HP:0002136)3.58171145
21Eczematoid dermatitis (HP:0000976)3.52094181
22Meningitis (HP:0001287)3.48699827
23Vasculitis (HP:0002633)3.44293994
24Myositis (HP:0100614)3.40339753
25Gaze-evoked nystagmus (HP:0000640)3.37189514
26Encephalitis (HP:0002383)3.23540812
27Generalized tonic-clonic seizures (HP:0002069)3.18003972
28Recurrent bacterial skin infections (HP:0005406)3.17897589
29Recurrent sinusitis (HP:0011108)3.16759998
30Orchitis (HP:0100796)3.15922816
31Abnormality of T cell physiology (HP:0011840)3.15135387
32Dysmetria (HP:0001310)3.14453932
33Truncal ataxia (HP:0002078)3.13562766
34Hemiplegia (HP:0002301)3.11661197
35Impaired smooth pursuit (HP:0007772)3.03354291
36Lymphopenia (HP:0001888)3.02046647
37Recurrent abscess formation (HP:0002722)3.00892830
38Amblyopia (HP:0000646)2.98337866
39Severe combined immunodeficiency (HP:0004430)2.93135605
40Inflammation of the large intestine (HP:0002037)2.89910784
41Prolonged bleeding time (HP:0003010)2.83749317
42Gastrointestinal stroma tumor (HP:0100723)2.83030861
43Impaired social interactions (HP:0000735)2.82398911
44Abnormal social behavior (HP:0012433)2.82398911
45Dysmetric saccades (HP:0000641)2.82287842
46Poor eye contact (HP:0000817)2.81876306
47Gastrointestinal inflammation (HP:0004386)2.81282617
48Mediastinal lymphadenopathy (HP:0100721)2.80507312
49Impaired vibration sensation in the lower limbs (HP:0002166)2.79068159
50Abnormality of T cells (HP:0002843)2.77305616
51Abnormality of cells of the lymphoid lineage (HP:0012140)2.72700393
52Combined immunodeficiency (HP:0005387)2.72365898
53Action tremor (HP:0002345)2.68745150
54Recurrent skin infections (HP:0001581)2.67941890
55Chronic otitis media (HP:0000389)2.64217501
56Progressive inability to walk (HP:0002505)2.63436969
57Abnormal delayed hypersensitivity skin test (HP:0002963)2.62362912
58IgM deficiency (HP:0002850)2.62225948
59Gastrointestinal infarctions (HP:0005244)2.61232297
60Pulmonary infiltrates (HP:0002113)2.60739281
61Urinary urgency (HP:0000012)2.59855517
62Excessive salivation (HP:0003781)2.57067849
63Drooling (HP:0002307)2.57067849
64Panhypogammaglobulinemia (HP:0003139)2.56824602
65Stereotypic behavior (HP:0000733)2.56107379
66Abnormality of ocular smooth pursuit (HP:0000617)2.55440082
67Absent rod-and cone-mediated responses on ERG (HP:0007688)2.53173916
68Colitis (HP:0002583)2.53057522
69Attenuation of retinal blood vessels (HP:0007843)2.52442613
70Supranuclear gaze palsy (HP:0000605)2.50563916
71Nasal polyposis (HP:0100582)2.46658406
72Bronchitis (HP:0012387)2.45403818
73Genetic anticipation (HP:0003743)2.45218810
74Abnormality of oral frenula (HP:0000190)2.44762921
75Scanning speech (HP:0002168)2.43411142
76Dysdiadochokinesis (HP:0002075)2.37920954
77Eosinophilia (HP:0001880)2.37066952
78Thyroiditis (HP:0100646)2.36283756
79Leukocytosis (HP:0001974)2.36233083
80Hemoptysis (HP:0002105)2.35919847
81Depression (HP:0000716)2.34604711
82Increased IgM level (HP:0003496)2.33419894
83Urinary bladder sphincter dysfunction (HP:0002839)2.33407946
84IgA deficiency (HP:0002720)2.33375355
85Deep palmar crease (HP:0006191)2.32889973
86Inability to walk (HP:0002540)2.32583560
87Abnormal rod and cone electroretinograms (HP:0008323)2.31582911
88Abnormality of macrophages (HP:0004311)2.30625392
89Keratoconjunctivitis (HP:0001096)2.30398631
90Dyskinesia (HP:0100660)2.29284299
91Elevated erythrocyte sedimentation rate (HP:0003565)2.28778739
92Stomach cancer (HP:0012126)2.28559364
93Granulocytopenia (HP:0001913)2.26248858
94Spastic gait (HP:0002064)2.26209585
95Abnormality of B cell number (HP:0010975)2.24701752
96Recurrent bronchitis (HP:0002837)2.24523846
97Recurrent cutaneous fungal infections (HP:0011370)2.24439746
98Chronic mucocutaneous candidiasis (HP:0002728)2.24439746
99Congenital stationary night blindness (HP:0007642)2.22557342
100Abnormal eating behavior (HP:0100738)2.20651796
101Status epilepticus (HP:0002133)2.19305011
102Keratoconjunctivitis sicca (HP:0001097)2.18273335
103Chest pain (HP:0100749)2.16954217
104Abnormality of the prostate (HP:0008775)2.16700965
105Cerebral inclusion bodies (HP:0100314)2.16230743
106Recurrent fungal infections (HP:0002841)2.13704842
107Abnormality of the fingertips (HP:0001211)2.11921531
108Constricted visual fields (HP:0001133)2.11508325
109IgG deficiency (HP:0004315)2.11363551
110Autoimmune hemolytic anemia (HP:0001890)2.10451503
111Recurrent viral infections (HP:0004429)2.09203227
112Obstructive lung disease (HP:0006536)2.09119848
113Chronic obstructive pulmonary disease (HP:0006510)2.09119848
114Abnormality of the lower motor neuron (HP:0002366)2.09056247
115Joint swelling (HP:0001386)2.08739407
116Abnormal hair whorl (HP:0010721)2.07682444
117Absent speech (HP:0001344)2.06506101
118Bronchiectasis (HP:0002110)2.04963175
119Epistaxis (HP:0000421)2.03012723
120Spontaneous hematomas (HP:0007420)2.00925617
121Arterial thrombosis (HP:0004420)2.00470637
122Generalized hypopigmentation of hair (HP:0011358)2.00428888
123Protruding tongue (HP:0010808)1.99827351
124Amyotrophic lateral sclerosis (HP:0007354)1.99420555
125Spinal canal stenosis (HP:0003416)1.98454270
126Annular pancreas (HP:0001734)1.97094194
127Hemiparesis (HP:0001269)1.96932554
128Papilledema (HP:0001085)1.95382573
129Hypochromic anemia (HP:0001931)1.95000954
130Neoplasm of the tracheobronchial system (HP:0100552)1.94400203
131Pulmonary embolism (HP:0002204)1.94186555
132Restrictive lung disease (HP:0002091)1.92737967
133Hypoplasia of the thymus (HP:0000778)1.91066127
134Abnormality of the renal cortex (HP:0011035)1.90702472
135Pustule (HP:0200039)1.90356035
136Anxiety (HP:0000739)1.90202216
137Alveolar cell carcinoma (HP:0006519)1.90119584
138Epileptiform EEG discharges (HP:0011182)1.89830833
139Recurrent otitis media (HP:0000403)1.88211935
140Chronic sinusitis (HP:0011109)1.88189542
141Abnormality of eosinophils (HP:0001879)1.87853425
142Gingival bleeding (HP:0000225)1.86947226
143Impaired vibratory sensation (HP:0002495)1.86924096
144Basal cell carcinoma (HP:0002671)1.84420012
145B lymphocytopenia (HP:0010976)1.84400309
146Abnormality of salivation (HP:0100755)1.84328621
147Blue irides (HP:0000635)1.82808584
148Acute hepatic failure (HP:0006554)1.82257686
149Lymphoma (HP:0002665)1.81512585
150Abnormality of the pleura (HP:0002103)1.80016181
151Fair hair (HP:0002286)1.79582276
152Ankle clonus (HP:0011448)1.78635127
153Pancreatic cysts (HP:0001737)1.78253752
154Intention tremor (HP:0002080)1.78148119
155Chronic diarrhea (HP:0002028)1.77891774
156Thickened helices (HP:0000391)1.76926712
157Abnormality of the nasal mucosa (HP:0000433)1.76466023
158Abnormality of saccadic eye movements (HP:0000570)1.75280940
159Decreased circulating renin level (HP:0003351)1.74970176
160Psychosis (HP:0000709)1.74923566
161Iris hypopigmentation (HP:0007730)1.74823695
162Hematochezia (HP:0002573)1.74707056
163Pointed chin (HP:0000307)1.74327034
164Verrucae (HP:0200043)1.74168065
165Papilloma (HP:0012740)1.74168065
166Decreased central vision (HP:0007663)1.72380649
167Postural instability (HP:0002172)1.72121216

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK34.02982599
2EPHA43.86851252
3FRK3.49414960
4TAOK33.15955917
5TXK3.15530844
6MAP3K133.10361064
7MAP3K93.03174819
8RIPK42.72600878
9MAP4K12.51438954
10GRK62.42647999
11BTK2.25985551
12MAP3K42.22405500
13SIK22.19886464
14MAP3K122.12581008
15ITK2.10040551
16DAPK22.04969144
17TYRO31.77340398
18NTRK21.75757137
19BLK1.72287166
20MAP2K71.72116693
21IKBKB1.68303656
22FES1.64939813
23PRKCH1.64236243
24PRPF4B1.62117915
25CSF1R1.61163040
26KSR21.60078557
27KIT1.59526415
28DAPK11.53027526
29CASK1.47246439
30JAK11.43766317
31IRAK41.41362211
32MINK11.40587234
33PAK61.37771880
34TNIK1.36764596
35MAP3K71.36260563
36STK381.32671140
37JAK31.30555492
38MAP2K41.28052632
39IKBKE1.27475634
40KSR11.24633840
41LYN1.24175049
42MST41.18163661
43BMPR21.15293134
44TNK21.14954678
45RAF11.12887055
46FGFR41.10025244
47CDK51.09475890
48TAOK11.09078082
49PRKCQ1.08503167
50FGFR31.07059732
51TBK11.05747670
52PIK3CA1.05545374
53PNCK1.03440296
54CAMKK10.99640571
55MARK20.98567079
56PLK20.98037403
57CDK190.97509375
58LCK0.96765823
59CAMK2B0.96173414
60PDK10.95334289
61MAP4K20.92420880
62STK100.92191730
63CHUK0.91018314
64FGFR20.90800468
65NLK0.89360242
66ADRBK20.88714882
67STK110.87496358
68IRAK10.85074824
69MAP2K20.84782057
70MAPKAPK30.84110966
71PRKD20.83533092
72PTK2B0.83518146
73GRK50.82408371
74CAMK2A0.81608284
75SYK0.80931040
76ZAP700.80779238
77PASK0.80032113
78HIPK20.79941236
79SGK30.79822018
80HCK0.79810242
81DMPK0.79127386
82NEK60.79108392
83SIK30.75522975
84PIK3CG0.74809295
85PRKCG0.74692241
86RET0.74205079
87NUAK10.73626563
88MAP3K140.73345866
89MAPK110.72722148
90MARK10.71918018
91SGK20.71492357
92TYK20.68476506
93CAMK10.68423029
94SGK10.68420838
95NTRK10.67374090
96MAPK120.66829567
97EPHB10.66281790
98MAP3K20.64982613
99FGR0.61740428
100JAK20.59662536
101FYN0.59154250
102ACVR1B0.59012450
103BMPR1B0.58899617
104ALK0.58679498
105GRK10.57778038
106PAK30.57753843
107DYRK1A0.56567307
108OXSR10.54846556
109ARAF0.54448147
110MAPK130.54186689
111MATK0.53071912
112MARK30.52987325
113MAPK70.52863107
114CSK0.51901915
115PKN20.51485980
116PDPK10.51123161
117TRIB30.50195570
118CAMKK20.49405291
119PIM10.49336177
120MUSK0.45795746
121RPS6KB20.45371957
122INSRR0.44469080
123ROCK20.43973177
124MAP3K10.43964750
125SGK4940.43163529
126SGK2230.43163529
127NME10.42466915
128EEF2K0.41612239
129PINK10.41187841
130CDC42BPA0.40280708
131PRKCI0.38397976
132ERN10.37876359
133PRKCZ0.37819517
134PRKD30.37638044
135MAP3K110.37259129
136PDGFRB0.36951191
137TEC0.35945697
138MAP3K100.35710402
139MAP2K60.35237682
140SIK10.34510758
141TRPM70.34471020
142UHMK10.34240851
143ABL10.32576041
144RPS6KA30.31978975

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.22637698
2Autoimmune thyroid disease_Homo sapiens_hsa053203.18964940
3Long-term potentiation_Homo sapiens_hsa047202.75690391
4Asthma_Homo sapiens_hsa053102.36021733
5Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.31496909
6Glutamatergic synapse_Homo sapiens_hsa047242.20995986
7Circadian entrainment_Homo sapiens_hsa047132.18903448
8Primary immunodeficiency_Homo sapiens_hsa053402.15648686
9Salivary secretion_Homo sapiens_hsa049702.13585131
10T cell receptor signaling pathway_Homo sapiens_hsa046602.13213599
11Morphine addiction_Homo sapiens_hsa050322.11856342
12Synaptic vesicle cycle_Homo sapiens_hsa047212.06270833
13Amphetamine addiction_Homo sapiens_hsa050312.06022203
14Olfactory transduction_Homo sapiens_hsa047401.88000039
15Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.84854728
16GABAergic synapse_Homo sapiens_hsa047271.82654731
17Gastric acid secretion_Homo sapiens_hsa049711.82464895
18Leishmaniasis_Homo sapiens_hsa051401.79568088
19Hematopoietic cell lineage_Homo sapiens_hsa046401.77689327
20Antigen processing and presentation_Homo sapiens_hsa046121.75488243
21Aldosterone synthesis and secretion_Homo sapiens_hsa049251.69687486
22Dopaminergic synapse_Homo sapiens_hsa047281.68649269
23Phosphatidylinositol signaling system_Homo sapiens_hsa040701.61103413
24Renin secretion_Homo sapiens_hsa049241.58829424
25Oxytocin signaling pathway_Homo sapiens_hsa049211.58279524
26Insulin secretion_Homo sapiens_hsa049111.57971112
27Long-term depression_Homo sapiens_hsa047301.54119562
28Cholinergic synapse_Homo sapiens_hsa047251.53552561
29Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.53422591
30Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.53294280
31RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.52801065
32Calcium signaling pathway_Homo sapiens_hsa040201.48488770
33Taste transduction_Homo sapiens_hsa047421.45427240
34Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.41154375
35Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.36297831
36Viral myocarditis_Homo sapiens_hsa054161.33257006
37Jak-STAT signaling pathway_Homo sapiens_hsa046301.32763044
38Staphylococcus aureus infection_Homo sapiens_hsa051501.32207669
39Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.30655355
40GnRH signaling pathway_Homo sapiens_hsa049121.29372098
41Herpes simplex infection_Homo sapiens_hsa051681.21270965
42Toll-like receptor signaling pathway_Homo sapiens_hsa046201.21039743
43Serotonergic synapse_Homo sapiens_hsa047261.18113720
44cAMP signaling pathway_Homo sapiens_hsa040241.16978555
45Tuberculosis_Homo sapiens_hsa051521.15272441
46Collecting duct acid secretion_Homo sapiens_hsa049661.14871439
47Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.10625033
48Estrogen signaling pathway_Homo sapiens_hsa049151.09977224
49cGMP-PKG signaling pathway_Homo sapiens_hsa040221.09365902
50Influenza A_Homo sapiens_hsa051641.08450080
51VEGF signaling pathway_Homo sapiens_hsa043701.06926809
52Graft-versus-host disease_Homo sapiens_hsa053321.03009627
53Type II diabetes mellitus_Homo sapiens_hsa049301.02778393
54Choline metabolism in cancer_Homo sapiens_hsa052311.00854842
55NOD-like receptor signaling pathway_Homo sapiens_hsa046211.00700980
56Cocaine addiction_Homo sapiens_hsa050300.97950590
57Toxoplasmosis_Homo sapiens_hsa051450.97806676
58Chemokine signaling pathway_Homo sapiens_hsa040620.96608738
59Phototransduction_Homo sapiens_hsa047440.96261801
60Vascular smooth muscle contraction_Homo sapiens_hsa042700.95011027
61Hepatitis C_Homo sapiens_hsa051600.94984247
62ErbB signaling pathway_Homo sapiens_hsa040120.94881834
63Pancreatic secretion_Homo sapiens_hsa049720.94390532
64Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.93887164
65ABC transporters_Homo sapiens_hsa020100.93629342
66Glioma_Homo sapiens_hsa052140.92994858
67Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.92963634
68TNF signaling pathway_Homo sapiens_hsa046680.92200873
69B cell receptor signaling pathway_Homo sapiens_hsa046620.91639159
70Osteoclast differentiation_Homo sapiens_hsa043800.89442711
71MAPK signaling pathway_Homo sapiens_hsa040100.88489161
72SNARE interactions in vesicular transport_Homo sapiens_hsa041300.88131737
73Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.86855288
74Phospholipase D signaling pathway_Homo sapiens_hsa040720.86649204
75alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.85777117
76Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.83869554
77Gap junction_Homo sapiens_hsa045400.83767564
78Glycerophospholipid metabolism_Homo sapiens_hsa005640.83628023
79Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.83412539
80Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.83089797
81Axon guidance_Homo sapiens_hsa043600.82022183
82Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.81446143
83Dorso-ventral axis formation_Homo sapiens_hsa043200.80520852
84Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.79610633
85Inositol phosphate metabolism_Homo sapiens_hsa005620.79507920
86Melanogenesis_Homo sapiens_hsa049160.79113516
87Linoleic acid metabolism_Homo sapiens_hsa005910.77897498
88Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.76725848
89Neurotrophin signaling pathway_Homo sapiens_hsa047220.76274927
90Measles_Homo sapiens_hsa051620.75784251
91Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.75719939
92Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.74523855
93Type I diabetes mellitus_Homo sapiens_hsa049400.74248700
94Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.73949096
95Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.71986758
96Non-small cell lung cancer_Homo sapiens_hsa052230.70102509
97Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.69990217
98Platelet activation_Homo sapiens_hsa046110.69053653
99Rap1 signaling pathway_Homo sapiens_hsa040150.68850740
100Carbohydrate digestion and absorption_Homo sapiens_hsa049730.67828485
101Thyroid hormone synthesis_Homo sapiens_hsa049180.67792819
102Sphingolipid signaling pathway_Homo sapiens_hsa040710.67372305
103Colorectal cancer_Homo sapiens_hsa052100.65355753
104Regulation of autophagy_Homo sapiens_hsa041400.63001712
105Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.61619039
106Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.60952107
107Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.60918602
108mTOR signaling pathway_Homo sapiens_hsa041500.60491474
109Ras signaling pathway_Homo sapiens_hsa040140.60078455
110Endometrial cancer_Homo sapiens_hsa052130.59471240
111African trypanosomiasis_Homo sapiens_hsa051430.59235147
112Intestinal immune network for IgA production_Homo sapiens_hsa046720.57702187
113Epstein-Barr virus infection_Homo sapiens_hsa051690.56296602
114Thyroid hormone signaling pathway_Homo sapiens_hsa049190.55585259
115Dilated cardiomyopathy_Homo sapiens_hsa054140.54772454
116Leukocyte transendothelial migration_Homo sapiens_hsa046700.53448280
117Prolactin signaling pathway_Homo sapiens_hsa049170.52578319
118FoxO signaling pathway_Homo sapiens_hsa040680.52467051
119Nitrogen metabolism_Homo sapiens_hsa009100.51828610
120Endocytosis_Homo sapiens_hsa041440.51770354
121Pancreatic cancer_Homo sapiens_hsa052120.50758956
122Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.49483498
123Acute myeloid leukemia_Homo sapiens_hsa052210.49269481
124Regulation of actin cytoskeleton_Homo sapiens_hsa048100.48703083
125Ether lipid metabolism_Homo sapiens_hsa005650.48572797
126Allograft rejection_Homo sapiens_hsa053300.47302187
127Apoptosis_Homo sapiens_hsa042100.46920567
128Hepatitis B_Homo sapiens_hsa051610.46632128
129Oocyte meiosis_Homo sapiens_hsa041140.46564869
130Rheumatoid arthritis_Homo sapiens_hsa053230.46157937
131Glucagon signaling pathway_Homo sapiens_hsa049220.45348513
132NF-kappa B signaling pathway_Homo sapiens_hsa040640.45330772
133Circadian rhythm_Homo sapiens_hsa047100.43920064
134Renal cell carcinoma_Homo sapiens_hsa052110.43684512
135Insulin resistance_Homo sapiens_hsa049310.42187193
136Viral carcinogenesis_Homo sapiens_hsa052030.34135458
137Legionellosis_Homo sapiens_hsa051340.33776657

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