SIDT2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1alpha-linolenic acid metabolic process (GO:0036109)4.36592074
2negative regulation of cell killing (GO:0031342)4.25918311
3negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.25918311
4antigen processing and presentation of endogenous peptide antigen (GO:0002483)4.09255409
5antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)4.09255409
6triglyceride-rich lipoprotein particle remodeling (GO:0034370)4.04733881
7erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)3.97420573
8L-phenylalanine catabolic process (GO:0006559)3.97420573
9protein carboxylation (GO:0018214)3.92754820
10peptidyl-glutamic acid carboxylation (GO:0017187)3.92754820
11antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.91476266
12complement activation, alternative pathway (GO:0006957)3.89014451
13L-phenylalanine metabolic process (GO:0006558)3.84637279
14erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)3.84637279
15negative regulation of fibrinolysis (GO:0051918)3.84505161
16regulation of cholesterol homeostasis (GO:2000188)3.74964292
17antigen processing and presentation of endogenous antigen (GO:0019883)3.72960885
18urea cycle (GO:0000050)3.63834221
19urea metabolic process (GO:0019627)3.63834221
20cysteine metabolic process (GO:0006534)3.63367944
21regulation of protein activation cascade (GO:2000257)3.63031243
22sulfur amino acid catabolic process (GO:0000098)3.59721408
23valine metabolic process (GO:0006573)3.59319880
24fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)3.54964636
25aromatic amino acid family catabolic process (GO:0009074)3.54585907
26regulation of complement activation (GO:0030449)3.49133578
27regulation of triglyceride catabolic process (GO:0010896)3.47748586
28high-density lipoprotein particle remodeling (GO:0034375)3.46810661
29negative regulation of cholesterol transport (GO:0032375)3.43917169
30negative regulation of sterol transport (GO:0032372)3.43917169
31low-density lipoprotein particle clearance (GO:0034383)3.40341710
32kynurenine metabolic process (GO:0070189)3.39799778
33regulation of gamma-delta T cell differentiation (GO:0045586)3.35322271
34plasma lipoprotein particle clearance (GO:0034381)3.34902332
35detection of other organism (GO:0098543)3.32525319
36detection of bacterium (GO:0016045)3.30787620
37reverse cholesterol transport (GO:0043691)3.30566005
38phospholipid efflux (GO:0033700)3.30310311
39regulation of fibrinolysis (GO:0051917)3.28677571
40nitrogen cycle metabolic process (GO:0071941)3.24331752
41lysine metabolic process (GO:0006553)3.23614162
42lysine catabolic process (GO:0006554)3.23614162
43positive regulation of fatty acid beta-oxidation (GO:0032000)3.23519340
44phospholipid homeostasis (GO:0055091)3.23132707
45regulation of fatty acid beta-oxidation (GO:0031998)3.22309059
46indole-containing compound catabolic process (GO:0042436)3.20513785
47indolalkylamine catabolic process (GO:0046218)3.20513785
48tryptophan catabolic process (GO:0006569)3.20513785
49bile acid biosynthetic process (GO:0006699)3.15217679
50modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.11985572
51positive regulation by organism of defense response of other organism involved in symbiotic interact3.11985572
52modulation by symbiont of host immune response (GO:0052553)3.11985572
53positive regulation by symbiont of host defense response (GO:0052509)3.11985572
54modulation by symbiont of host defense response (GO:0052031)3.11985572
55modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.11985572
56regulation of cholesterol storage (GO:0010885)3.11303768
57positive regulation of lipid catabolic process (GO:0050996)3.10898332
58regulation of vascular endothelial growth factor signaling pathway (GO:1900746)3.09641278
59macrophage activation involved in immune response (GO:0002281)3.08194345
60glyoxylate metabolic process (GO:0046487)3.08090765
61tryptophan metabolic process (GO:0006568)3.07118605
62homocysteine metabolic process (GO:0050667)3.04812460
63amino-acid betaine metabolic process (GO:0006577)3.04425317
64positive regulation of gamma-delta T cell activation (GO:0046645)3.02174684
65regulation of gamma-delta T cell activation (GO:0046643)2.99588572
662-oxoglutarate metabolic process (GO:0006103)2.98719188
67positive regulation of triglyceride metabolic process (GO:0090208)2.98244664
68negative regulation of erythrocyte differentiation (GO:0045647)2.95555124
69serine family amino acid catabolic process (GO:0009071)2.94224223
70plasma lipoprotein particle assembly (GO:0034377)2.92967276
71triglyceride homeostasis (GO:0070328)2.92359802
72acylglycerol homeostasis (GO:0055090)2.92359802
73regulation of dendritic cell antigen processing and presentation (GO:0002604)2.90231987
74protein-lipid complex remodeling (GO:0034368)2.89908981
75macromolecular complex remodeling (GO:0034367)2.89908981
76plasma lipoprotein particle remodeling (GO:0034369)2.89908981
77regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.89785476
78protein-lipid complex assembly (GO:0065005)2.88707941
79positive regulation of triglyceride lipase activity (GO:0061365)2.85320021
80positive regulation of lipoprotein lipase activity (GO:0051006)2.85320021
81regulation of cholesterol esterification (GO:0010872)2.83020230
82regulation of plasminogen activation (GO:0010755)2.82211528
83ethanol oxidation (GO:0006069)2.81925405
84detection of external biotic stimulus (GO:0098581)2.81140350
85regulation of interferon-beta biosynthetic process (GO:0045357)2.80418469
86fibrinolysis (GO:0042730)2.79780032
87growth hormone receptor signaling pathway (GO:0060396)2.79391820
88cholesterol efflux (GO:0033344)2.78298762
89negative regulation of lipid transport (GO:0032369)2.77860227
90bile acid metabolic process (GO:0008206)2.77797034
91immunoglobulin mediated immune response (GO:0016064)2.77775451
92dicarboxylic acid biosynthetic process (GO:0043650)2.76709166
93activated T cell proliferation (GO:0050798)2.76228552
94acute-phase response (GO:0006953)2.76165179
95regulation of antigen processing and presentation (GO:0002577)2.73641719
96cholesterol homeostasis (GO:0042632)2.71711285
97complement activation (GO:0006956)2.70737128
98sterol homeostasis (GO:0055092)2.70578947
99apoptotic cell clearance (GO:0043277)2.69996471
100negative regulation of lymphocyte mediated immunity (GO:0002707)2.68670949
101cellular extravasation (GO:0045123)2.68657162
102cellular modified amino acid catabolic process (GO:0042219)2.68297332
103positive regulation of triglyceride biosynthetic process (GO:0010867)2.63535585
104lipoprotein metabolic process (GO:0042157)2.62562111
105negative regulation of interleukin-12 production (GO:0032695)2.61571474
106regulation of triglyceride metabolic process (GO:0090207)2.61459739
107neutrophil activation involved in immune response (GO:0002283)2.60962623
108complement activation, classical pathway (GO:0006958)2.59853833
109acetyl-CoA metabolic process (GO:0006084)2.58230892
110regulation of mast cell degranulation (GO:0043304)2.56902888
111response to peptidoglycan (GO:0032494)2.56826674
112positive regulation of fatty acid biosynthetic process (GO:0045723)2.55807248
113positive regulation of cellular amide metabolic process (GO:0034250)2.55751745
114regulation of T-helper 2 cell differentiation (GO:0045628)2.54428513
115positive regulation of antigen processing and presentation (GO:0002579)2.54362045
116regulation of B cell receptor signaling pathway (GO:0050855)2.54049818
117regulation of interleukin-12 biosynthetic process (GO:0045075)2.53982652
118detection of molecule of bacterial origin (GO:0032490)2.53612769
119positive regulation of fatty acid oxidation (GO:0046321)2.52990813
120positive regulation of lipid storage (GO:0010884)2.51690597
121positive thymic T cell selection (GO:0045059)2.51662928
122protein-lipid complex subunit organization (GO:0071825)2.50578493
123plasma lipoprotein particle organization (GO:0071827)2.50298853
124tyrosine metabolic process (GO:0006570)2.50038769
125cellular response to growth hormone stimulus (GO:0071378)2.49951316
126regulation of humoral immune response (GO:0002920)2.49676298
127detection of biotic stimulus (GO:0009595)2.49514438
128epoxygenase P450 pathway (GO:0019373)2.49409397
129mannose metabolic process (GO:0006013)2.49306633
130negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.49108324
131B cell receptor signaling pathway (GO:0050853)2.48957861
132response to muramyl dipeptide (GO:0032495)2.48594702
133regulation of cholesterol transport (GO:0032374)2.48454467
134regulation of sterol transport (GO:0032371)2.48454467
135negative regulation of leukocyte mediated immunity (GO:0002704)2.46891191
136germinal center formation (GO:0002467)2.44271300
137regulation of myeloid leukocyte mediated immunity (GO:0002886)2.40399176
138regulation of leukocyte degranulation (GO:0043300)2.40293259
139negative thymic T cell selection (GO:0045060)2.39174339
140positive regulation of type 2 immune response (GO:0002830)2.39090647
141thymic T cell selection (GO:0045061)2.38901372
142T cell selection (GO:0045058)2.38798429
143negative regulation of T cell mediated immunity (GO:0002710)2.37966919
144antigen processing and presentation via MHC class Ib (GO:0002475)2.36156758
145negative regulation of interleukin-6 production (GO:0032715)2.36068831
146interferon-gamma-mediated signaling pathway (GO:0060333)2.35454070
147regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.34482312
148regulation of mast cell activation involved in immune response (GO:0033006)2.34080210
149regulation of mast cell activation (GO:0033003)2.32425928
150positive regulation of Rap GTPase activity (GO:0032854)2.31478100
151negative regulation of interleukin-8 production (GO:0032717)2.30990773
152response to type I interferon (GO:0034340)2.30692958
153regulation of T cell mediated cytotoxicity (GO:0001914)2.29527755
154negative regulation of toll-like receptor signaling pathway (GO:0034122)2.27797313
155defense response to protozoan (GO:0042832)2.27144155
156negative regulation of cytokine production involved in immune response (GO:0002719)2.25749621
157cellular response to type I interferon (GO:0071357)2.25061654
158type I interferon signaling pathway (GO:0060337)2.25061654
159positive regulation of mast cell activation (GO:0033005)2.23864208
160peptide catabolic process (GO:0043171)2.22641747
161neutrophil activation (GO:0042119)2.22024098
162negative T cell selection (GO:0043383)2.21875201
163negative regulation of innate immune response (GO:0045824)2.21832278
164regulation of T cell tolerance induction (GO:0002664)2.21748063
165regulation of extracellular matrix disassembly (GO:0010715)2.21562574
166negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.21215166
167regulation of ARF protein signal transduction (GO:0032012)2.19997895
168macrophage activation (GO:0042116)2.19966452
169leukocyte aggregation (GO:0070486)2.19727378
170positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.18612927
171production of molecular mediator involved in inflammatory response (GO:0002532)2.17307144
172positive T cell selection (GO:0043368)2.14658192
173positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.13299485
174microglial cell activation (GO:0001774)2.12321213
175granulocyte activation (GO:0036230)2.11432966
176regulation of regulated secretory pathway (GO:1903305)2.10873835
177regulation of tolerance induction (GO:0002643)2.10161896
178positive regulation of T cell mediated cytotoxicity (GO:0001916)2.09901694
179regulation of type 2 immune response (GO:0002828)2.09683691
180response to laminar fluid shear stress (GO:0034616)2.08924201
181diacylglycerol metabolic process (GO:0046339)2.07525668
182regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.05844341
183negative regulation of granulocyte differentiation (GO:0030853)2.04715923
184negative regulation of alpha-beta T cell activation (GO:0046636)2.03842017
185myeloid cell activation involved in immune response (GO:0002275)2.03188815
186JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.01955268
187tolerance induction (GO:0002507)2.01346491
188T-helper 1 type immune response (GO:0042088)2.00768579
189response to protozoan (GO:0001562)1.99779554
190adhesion of symbiont to host cell (GO:0044650)1.99634537

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse5.88378836
2RXR_22158963_ChIP-Seq_LIVER_Mouse4.37850909
3PPARA_22158963_ChIP-Seq_LIVER_Mouse4.08988409
4PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.68250841
5TP63_17297297_ChIP-ChIP_HaCaT_Human3.63113955
6LXR_22158963_ChIP-Seq_LIVER_Mouse3.58661680
7NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.99495889
8FOXO1_23066095_ChIP-Seq_LIVER_Mouse2.66628048
9IRF8_22096565_ChIP-ChIP_GC-B_Human2.54072231
10CLOCK_20551151_ChIP-Seq_293T_Human2.48672080
11STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.38218605
12EGR1_23403033_ChIP-Seq_LIVER_Mouse2.38195110
13NR1I2_20693526_ChIP-Seq_LIVER_Mouse2.36735895
14FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.28239339
15STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.17210198
16RARG_19884340_ChIP-ChIP_MEFs_Mouse2.16538451
17TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.03305718
18VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.00744280
19CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.93734355
20MYC_22102868_ChIP-Seq_BL_Human1.88007242
21THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.81918720
22RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.81202865
23NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.76562917
24IKZF1_21737484_ChIP-ChIP_HCT116_Human1.75860651
25EGR1_19374776_ChIP-ChIP_THP-1_Human1.72104085
26BP1_19119308_ChIP-ChIP_Hs578T_Human1.71003271
27ELK3_25401928_ChIP-Seq_HUVEC_Human1.70999788
28IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.69041699
29DROSHA_22980978_ChIP-Seq_HELA_Human1.68802751
30NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.67541291
31TCF7_22412390_ChIP-Seq_EML_Mouse1.65769871
32* ESR2_21235772_ChIP-Seq_MCF-7_Human1.63788680
33MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.58768547
34TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.57918215
35KDM2B_26808549_Chip-Seq_SUP-B15_Human1.57588972
36* KDM2B_26808549_Chip-Seq_DND41_Human1.57412355
37SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.57013265
38MAF_26560356_Chip-Seq_TH1_Human1.56322234
39SPI1_23127762_ChIP-Seq_K562_Human1.55912082
40STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.55880299
41* LXR_22292898_ChIP-Seq_THP-1_Human1.55176080
42MYB_21317192_ChIP-Seq_ERMYB_Mouse1.54239267
43ZNF263_19887448_ChIP-Seq_K562_Human1.53476973
44TRIM28_21343339_ChIP-Seq_HEK293_Human1.52579040
45EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.51854098
46* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.51635587
47KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.51587228
48BRD4_27068464_Chip-Seq_AML-cells_Mouse1.51463966
49IRF8_27001747_Chip-Seq_BMDM_Mouse1.48925086
50RUNX_20019798_ChIP-Seq_JUKART_Human1.48421116
51FOXO3_23340844_ChIP-Seq_DLD1_Human1.47719860
52TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.47131577
53ESR1_21235772_ChIP-Seq_MCF-7_Human1.46469894
54KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.45128038
55VDR_21846776_ChIP-Seq_THP-1_Human1.44039861
56* RACK7_27058665_Chip-Seq_MCF-7_Human1.42902872
57E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.39987759
58* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.39325533
59VDR_24787735_ChIP-Seq_THP-1_Human1.35828880
60STAT6_21828071_ChIP-Seq_BEAS2B_Human1.34543226
61* FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.34267057
62MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.33024347
63CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.30905230
64STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.29987267
65IRF8_21731497_ChIP-ChIP_J774_Mouse1.28982892
66UTX_26944678_Chip-Seq_JUKART_Human1.28776404
67SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.28175014
68RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.28005206
69Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.27046601
70DNAJC2_21179169_ChIP-ChIP_NT2_Human1.23650265
71TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.23577702
72P68_20966046_ChIP-Seq_HELA_Human1.22416628
73MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.22370854
74BCL6_27268052_Chip-Seq_Bcells_Human1.21958489
75GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.21777841
76FOXA2_19822575_ChIP-Seq_HepG2_Human1.21433898
77BCOR_27268052_Chip-Seq_Bcells_Human1.20988165
78SOX2_27498859_Chip-Seq_STOMACH_Mouse1.20731715
79GATA1_19941826_ChIP-Seq_K562_Human1.20399490
80PPAR_26484153_Chip-Seq_NCI-H1993_Human1.19358662
81GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.18755597
82GATA1_22025678_ChIP-Seq_K562_Human1.18372312
83* CTCF_27219007_Chip-Seq_ERYTHROID_Human1.17753287
84PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.16946470
85CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.16323532
86SMC4_20622854_ChIP-Seq_HELA_Human1.16080817
87* ATF3_27146783_Chip-Seq_COLON_Human1.16019457
88P300_27058665_Chip-Seq_ZR-75-30cells_Human1.15332461
89SA1_27219007_Chip-Seq_ERYTHROID_Human1.15273959
90MYB_26560356_Chip-Seq_TH2_Human1.14372224
91KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.14154595
92* MYB_26560356_Chip-Seq_TH1_Human1.13968892
93ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.13738060
94LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.11397102
95VDR_24763502_ChIP-Seq_THP-1_Human1.09931968
96* LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.09214569
97TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.08487807
98TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.06954073
99RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.06341433
100GATA2_19941826_ChIP-Seq_K562_Human1.05191046
101* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.04349557
102SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.03803254
103HIF1A_21447827_ChIP-Seq_MCF-7_Human1.03274204
104GATA2_21666600_ChIP-Seq_HMVEC_Human1.02856246
105NCOR1_26117541_ChIP-Seq_K562_Human1.02638860
106BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.02478919
107* SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.02477520
108KDM2B_26808549_Chip-Seq_JURKAT_Human1.01958887
109TBX20_22080862_ChIP-Seq_HEART_Mouse1.00939791
110TBX20_22328084_ChIP-Seq_HEART_Mouse1.00939791
111P63_26484246_Chip-Seq_KERATINOCYTES_Human1.00282800
112PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.00204042
113GATA1_19941827_ChIP-Seq_MEL_Mouse0.99317436
114CTCF_27219007_Chip-Seq_Bcells_Human0.99288636
115RUNX1_27514584_Chip-Seq_MCF-7_Human0.99260761
116CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.99163060
117SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.98508730
118ELF1_20517297_ChIP-Seq_JURKAT_Human0.98342998
119TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.97615778
120GATA4_25053715_ChIP-Seq_YYC3_Human0.97536949
121SCL_19346495_ChIP-Seq_HPC-7_Human0.96688225
122E2F1_20622854_ChIP-Seq_HELA_Human0.96476505
123* FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.95771098
124RUNX1_22412390_ChIP-Seq_EML_Mouse0.95266889
125SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.95170136
126HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.94960579
127TP63_22573176_ChIP-Seq_HFKS_Human0.94905749
128GATA6_25053715_ChIP-Seq_YYC3_Human0.94475996
129STAT4_19710469_ChIP-ChIP_TH1__Mouse0.94356468
130MAF_26560356_Chip-Seq_TH2_Human0.93509198
131PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.93367809
132CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.92809753
133* SA1_27219007_Chip-Seq_Bcells_Human0.90804161
134GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.90620413
135IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.89677335
136CREB1_26743006_Chip-Seq_LNCaP_Human0.89066454
137KDM2B_26808549_Chip-Seq_K562_Human0.88505838
138* PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse0.88221669
139SOX9_24532713_ChIP-Seq_HFSC_Mouse0.88186332
140GATA3_27048872_Chip-Seq_THYMUS_Human0.87457513

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005360_urolithiasis4.34238046
2MP0002139_abnormal_hepatobiliary_system4.17298279
3MP0005365_abnormal_bile_salt3.24220147
4MP0003705_abnormal_hypodermis_morpholog3.23698009
5MP0005085_abnormal_gallbladder_physiolo3.03488675
6MP0009840_abnormal_foam_cell2.93452348
7MP0003172_abnormal_lysosome_physiology2.77866272
8MP0003191_abnormal_cellular_cholesterol2.39708660
9MP0010329_abnormal_lipoprotein_level2.38484876
10MP0003252_abnormal_bile_duct2.36259789
11MP0008438_abnormal_cutaneous_collagen2.28154460
12MP0008875_abnormal_xenobiotic_pharmacok2.22648388
13MP0003300_gastrointestinal_ulcer2.21771672
14MP0003436_decreased_susceptibility_to1.99165972
15MP0001666_abnormal_nutrient_absorption1.83182969
16MP0000609_abnormal_liver_physiology1.82401893
17MP0002254_reproductive_system_inflammat1.81363397
18MP0003303_peritoneal_inflammation1.78871546
19MP0005083_abnormal_biliary_tract1.76942194
20MP0005275_abnormal_skin_tensile1.76756991
21MP0010234_abnormal_vibrissa_follicle1.75563084
22MP0000685_abnormal_immune_system1.74409967
23MP0004947_skin_inflammation1.68434887
24MP0002148_abnormal_hypersensitivity_rea1.66915164
25MP0001986_abnormal_taste_sensitivity1.59853269
26MP0003183_abnormal_peptide_metabolism1.59156762
27MP0010352_gastrointestinal_tract_polyps1.58375501
28MP0003566_abnormal_cell_adhesion1.55681682
29MP0005670_abnormal_white_adipose1.55486553
30MP0005332_abnormal_amino_acid1.49395232
31MP0002118_abnormal_lipid_homeostasis1.45935622
32MP0002138_abnormal_hepatobiliary_system1.43051880
33MP0001835_abnormal_antigen_presentation1.42192747
34MP0003806_abnormal_nucleotide_metabolis1.41361542
35MP0002166_altered_tumor_susceptibility1.36261736
36MP0004185_abnormal_adipocyte_glucose1.34616624
37MP0008004_abnormal_stomach_pH1.34286996
38MP0002060_abnormal_skin_morphology1.34141625
39MP0001790_abnormal_immune_system1.30433004
40MP0005387_immune_system_phenotype1.30433004
41MP0004019_abnormal_vitamin_homeostasis1.29985482
42MP0003879_abnormal_hair_cell1.29184389
43MP0004130_abnormal_muscle_cell1.28636220
44MP0003828_pulmonary_edema1.28032486
45MP0003866_abnormal_defecation1.27553504
46MP0005023_abnormal_wound_healing1.26295681
47MP0005319_abnormal_enzyme/_coenzyme1.26131349
48MP0005464_abnormal_platelet_physiology1.23053037
49MP0002796_impaired_skin_barrier1.22453224
50MP0003690_abnormal_glial_cell1.21135252
51MP0005666_abnormal_adipose_tissue1.20918845
52MP0001533_abnormal_skeleton_physiology1.20862851
53MP0005058_abnormal_lysosome_morphology1.19350255
54MP0003453_abnormal_keratinocyte_physiol1.18986637
55MP0000604_amyloidosis1.17230323
56MP0009643_abnormal_urine_homeostasis1.16410074
57MP0003195_calcinosis1.16376745
58MP0001853_heart_inflammation1.14948511
59MP0004883_abnormal_blood_vessel1.14502088
60MP0001800_abnormal_humoral_immune1.14482480
61MP0003329_amyloid_beta_deposits1.13969518
62MP0003656_abnormal_erythrocyte_physiolo1.13343093
63MP0005409_darkened_coat_color1.13187276
64MP0000716_abnormal_immune_system1.13129918
65MP0002419_abnormal_innate_immunity1.09033583
66MP0004858_abnormal_nervous_system1.08963345
67MP0005310_abnormal_salivary_gland1.08356576
68MP0005584_abnormal_enzyme/coenzyme_acti1.06667201
69MP0000249_abnormal_blood_vessel1.06502871
70MP0010155_abnormal_intestine_physiology1.06161773
71MP0006082_CNS_inflammation1.06003437
72MP0001881_abnormal_mammary_gland1.05691632
73MP0004381_abnormal_hair_follicle1.04968971
74MP0001845_abnormal_inflammatory_respons1.04349375
75MP0008469_abnormal_protein_level1.03979888
76MP0005000_abnormal_immune_tolerance1.03955906
77MP0005025_abnormal_response_to1.03923937
78MP0002933_joint_inflammation1.03633857
79MP0009785_altered_susceptibility_to1.03097479
80MP0003763_abnormal_thymus_physiology1.01506007
81MP0004510_myositis1.01461441
82MP0000598_abnormal_liver_morphology1.01176999
83MP0009384_cardiac_valve_regurgitation0.98904209
84MP0002452_abnormal_antigen_presenting0.98339831
85MP0005451_abnormal_body_composition0.97924046
86MP0009764_decreased_sensitivity_to0.97741872
87MP0003279_aneurysm0.97473288
88MP0002006_tumorigenesis0.97382057
89MP0005076_abnormal_cell_differentiation0.96588374
90MP0008961_abnormal_basal_metabolism0.96440182
91MP0005164_abnormal_response_to0.96357200
92MP0008260_abnormal_autophagy0.96252990
93MP0001958_emphysema0.95382448
94MP0003045_fibrosis0.93647698
95MP0002723_abnormal_immune_serum0.91470605
96MP0005390_skeleton_phenotype0.90782248
97MP0002398_abnormal_bone_marrow0.90724775
98MP0002136_abnormal_kidney_physiology0.90236886
99MP0009763_increased_sensitivity_to0.89995253
100MP0001873_stomach_inflammation0.89171007
101MP0002876_abnormal_thyroid_physiology0.88819045
102MP0009278_abnormal_bone_marrow0.88764725
103MP0005535_abnormal_body_temperature0.88436236
104MP0005375_adipose_tissue_phenotype0.87759234
105MP0001501_abnormal_sleep_pattern0.87663971
106MP0003724_increased_susceptibility_to0.87375860
107MP0001216_abnormal_epidermal_layer0.86830317
108MP0005671_abnormal_response_to0.86617085
109MP0001851_eye_inflammation0.86100394
110MP0002405_respiratory_system_inflammati0.85782557
111MP0000767_abnormal_smooth_muscle0.85052791
112MP0001243_abnormal_dermal_layer0.84830949
113MP0009115_abnormal_fat_cell0.84679558
114MP0001663_abnormal_digestive_system0.84171661
115MP0000015_abnormal_ear_pigmentation0.83313406
116MP0001819_abnormal_immune_cell0.82925175
117MP0002420_abnormal_adaptive_immunity0.82824140
118MP0001765_abnormal_ion_homeostasis0.82693217
119MP0003091_abnormal_cell_migration0.81016728
120MP0002998_abnormal_bone_remodeling0.80413933
121MP0002168_other_aberrant_phenotype0.78896296
122MP0001849_ear_inflammation0.78722185
123MP0005167_abnormal_blood-brain_barrier0.78126944
124MP0000343_altered_response_to0.77601404
125MP0005448_abnormal_energy_balance0.77122743
126MP0003075_altered_response_to0.77038802
127MP0005166_decreased_susceptibility_to0.76293544
128MP0001664_abnormal_digestion0.75928915
129MP0002429_abnormal_blood_cell0.75662143
130MP0000689_abnormal_spleen_morphology0.75530615
131MP0001756_abnormal_urination0.75217292
132MP0002971_abnormal_brown_adipose0.75118277
133MP0009333_abnormal_splenocyte_physiolog0.74838391
134MP0005595_abnormal_vascular_smooth0.74423232
135MP0003448_altered_tumor_morphology0.74089769
136MP0000858_altered_metastatic_potential0.72884977
137MP0001545_abnormal_hematopoietic_system0.71707838
138MP0005397_hematopoietic_system_phenotyp0.71707838

Predicted human phenotypes

RankGene SetZ-score
1Deep venous thrombosis (HP:0002625)4.73246410
2Xanthomatosis (HP:0000991)4.09019497
3Abnormality of macrophages (HP:0004311)3.87455061
4Myositis (HP:0100614)3.80162497
5Myocardial infarction (HP:0001658)3.60363473
6Complement deficiency (HP:0004431)3.59264407
7Orchitis (HP:0100796)3.58496150
8Abnormality of monocarboxylic acid metabolism (HP:0010996)3.37827738
9Intrahepatic cholestasis (HP:0001406)3.36458736
10Optic neuritis (HP:0100653)3.31032161
11Retrobulbar optic neuritis (HP:0100654)3.31032161
12Recurrent abscess formation (HP:0002722)3.30511089
13Recurrent bacterial skin infections (HP:0005406)3.26524736
14Dysostosis multiplex (HP:0000943)3.18217850
15Abnormality of aromatic amino acid family metabolism (HP:0004338)3.18109228
16Hyperlipoproteinemia (HP:0010980)3.17827201
17Increased cerebral lipofuscin (HP:0011813)3.12444851
18Abnormality of glycolipid metabolism (HP:0010969)3.04823305
19Abnormality of liposaccharide metabolism (HP:0010968)3.04823305
20Abnormality of glycosphingolipid metabolism (HP:0004343)3.04823305
21Abnormality of polysaccharide metabolism (HP:0011012)3.03341035
22Abnormality of glycosaminoglycan metabolism (HP:0004371)3.03341035
23Abnormality of mucopolysaccharide metabolism (HP:0011020)3.03341035
24Peritonitis (HP:0002586)2.99564854
25Mucopolysacchariduria (HP:0008155)2.92660113
26Urinary glycosaminoglycan excretion (HP:0003541)2.92660113
27Abnormality of glutamine family amino acid metabolism (HP:0010902)2.92082754
28Abnormality of the common coagulation pathway (HP:0010990)2.87996105
29Hypobetalipoproteinemia (HP:0003563)2.85389576
30Abnormal delayed hypersensitivity skin test (HP:0002963)2.85182551
31Abnormality of complement system (HP:0005339)2.83534850
32Thin bony cortex (HP:0002753)2.76613406
33Increased neuronal autofluorescent lipopigment (HP:0002074)2.75560203
34Recurrent fungal infections (HP:0002841)2.72212772
35Vasculitis (HP:0002633)2.68513493
36Systemic lupus erythematosus (HP:0002725)2.67011825
37Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.65853973
38Prolonged partial thromboplastin time (HP:0003645)2.62668011
39Hypoalphalipoproteinemia (HP:0003233)2.62577185
40Protrusio acetabuli (HP:0003179)2.60427905
41Epidermoid cyst (HP:0200040)2.60098038
42Meningitis (HP:0001287)2.58433932
43Chronic mucocutaneous candidiasis (HP:0002728)2.58410515
44Recurrent cutaneous fungal infections (HP:0011370)2.58410515
45Vacuolated lymphocytes (HP:0001922)2.58110600
46Pulmonary infiltrates (HP:0002113)2.57028879
47Eczematoid dermatitis (HP:0000976)2.56907949
48Cerebral aneurysm (HP:0004944)2.56832506
49Joint hemorrhage (HP:0005261)2.55313052
50Hypolipoproteinemia (HP:0010981)2.53838778
51Recurrent skin infections (HP:0001581)2.52964443
52Aortic aneurysm (HP:0004942)2.51297932
53Hemoptysis (HP:0002105)2.51295001
54Emphysema (HP:0002097)2.49512931
55Stomatitis (HP:0010280)2.48367946
56Gingivitis (HP:0000230)2.47873961
57Recurrent gram-negative bacterial infections (HP:0005420)2.46429675
58Hyperammonemia (HP:0001987)2.46083780
59Autoimmune thrombocytopenia (HP:0001973)2.42936587
60Abnormality of sulfur amino acid metabolism (HP:0004339)2.41345624
61Abnormality of the level of lipoprotein cholesterol (HP:0010979)2.38666832
62Esophageal varix (HP:0002040)2.36265933
63Obstructive sleep apnea (HP:0002870)2.35910603
64Premature rupture of membranes (HP:0001788)2.34151490
65Mediastinal lymphadenopathy (HP:0100721)2.33333653
66Prolonged bleeding time (HP:0003010)2.32350650
67Keratoconjunctivitis sicca (HP:0001097)2.30802531
68Mitral stenosis (HP:0001718)2.30671743
69Mitral valve prolapse (HP:0001634)2.30151878
70Keratoconjunctivitis (HP:0001096)2.25884024
71Gingival bleeding (HP:0000225)2.24937671
72Hyperglycinuria (HP:0003108)2.24477098
73Right ventricular cardiomyopathy (HP:0011663)2.23676741
74Hypercholesterolemia (HP:0003124)2.22999692
75Osteolytic defects of the hand bones (HP:0009699)2.21786991
76Osteolytic defects of the phalanges of the hand (HP:0009771)2.21786991
77Gastrointestinal infarctions (HP:0005244)2.21374815
78Gastrointestinal stroma tumor (HP:0100723)2.20430934
79Cellulitis (HP:0100658)2.19524062
80Aortic dissection (HP:0002647)2.18970563
81Inflammation of the large intestine (HP:0002037)2.18657869
82Restrictive lung disease (HP:0002091)2.18022051
83Hydroxyprolinuria (HP:0003080)2.17632628
84Abnormality of proline metabolism (HP:0010907)2.17632628
85Encephalitis (HP:0002383)2.16992591
86Pustule (HP:0200039)2.16018668
87Gastrointestinal inflammation (HP:0004386)2.15831989
88Polycythemia (HP:0001901)2.15010274
89Asymmetric septal hypertrophy (HP:0001670)2.14859422
90Ketosis (HP:0001946)2.13066601
91Agammaglobulinemia (HP:0004432)2.09822267
92Loss of speech (HP:0002371)2.08563413
93Hemorrhage of the eye (HP:0011885)2.06240250
94Amyloidosis (HP:0011034)2.05395412
95Fat malabsorption (HP:0002630)2.05202599
96Abnormality of the fingertips (HP:0001211)2.04742823
97Increased mean platelet volume (HP:0011877)2.04229196
98Abnormality of serine family amino acid metabolism (HP:0010894)2.04114678
99Abnormality of glycine metabolism (HP:0010895)2.04114678
100Nephritis (HP:0000123)2.03122014
101Abnormality of fatty-acid metabolism (HP:0004359)2.02430400
102Epistaxis (HP:0000421)2.02165708
103Acne (HP:0001061)2.02038296
104Ectopia lentis (HP:0001083)2.00870670
105Abnormality of the intrinsic pathway (HP:0010989)2.00280352
106Elevated erythrocyte sedimentation rate (HP:0003565)2.00201448
107Abnormality of purine metabolism (HP:0004352)2.00030315
108Chest pain (HP:0100749)1.99221229
109Joint stiffness (HP:0001387)1.98817931
110Aneurysm (HP:0002617)1.98583222
111Cardiovascular calcification (HP:0011915)1.98045767
112Alopecia of scalp (HP:0002293)1.97609675
113Abnormal platelet volume (HP:0011876)1.97565201
114Segmental peripheral demyelination/remyelination (HP:0003481)1.97373822
115Obstructive lung disease (HP:0006536)1.97207776
116Chronic obstructive pulmonary disease (HP:0006510)1.97207776
117Hepatocellular carcinoma (HP:0001402)1.94732401
118Nasal polyposis (HP:0100582)1.93613474
119Vascular calcification (HP:0004934)1.92172971
120Upper limb amyotrophy (HP:0009129)1.92160723
121Distal upper limb amyotrophy (HP:0007149)1.92160723
122Dilatation of the ascending aorta (HP:0005111)1.92150916
123Abnormality of long-chain fatty-acid metabolism (HP:0010964)1.91623088
124Purpura (HP:0000979)1.90586087
125Hematochezia (HP:0002573)1.88586771
126Hypoglycemic coma (HP:0001325)1.88586418
127Broad metatarsal (HP:0001783)1.88220449
128Abnormality of the nasal mucosa (HP:0000433)1.88044949
129Hyperglycinemia (HP:0002154)1.88001228
130Ovoid vertebral bodies (HP:0003300)1.87845106
131Arterial thrombosis (HP:0004420)1.86479383
132Increased connective tissue (HP:0009025)1.85107320
133Abnormality of the Achilles tendon (HP:0005109)1.84698646
134Menorrhagia (HP:0000132)1.84639395
135Shallow orbits (HP:0000586)1.84075978
136Spondylolisthesis (HP:0003302)1.83451935
137Hand muscle atrophy (HP:0009130)1.83367473
138Skin nodule (HP:0200036)1.83225589
139Spastic diplegia (HP:0001264)1.83022687
140Pulmonary embolism (HP:0002204)1.82911781
141Spontaneous hematomas (HP:0007420)1.82328816
142Glomerulonephritis (HP:0000099)1.81862564
143Abnormal cartilage morphology (HP:0002763)1.81233307
144Increased IgE level (HP:0003212)1.80959265
145Malnutrition (HP:0004395)1.80898356
146Interstitial pulmonary disease (HP:0006530)1.79142872
147Ankle contracture (HP:0006466)1.78832256
148Hemiplegia (HP:0002301)1.78798363
149Abnormality of aspartate family amino acid metabolism (HP:0010899)1.77965430
150Hypochromic anemia (HP:0001931)1.77150465
151Atrophic scars (HP:0001075)1.76475380
152Thrombophlebitis (HP:0004418)1.73597934
153Abnormality of nucleobase metabolism (HP:0010932)1.73092905
154Diplopia (HP:0000651)1.71635091
155Abnormality of binocular vision (HP:0011514)1.71635091
156Abnormality of the pleura (HP:0002103)1.71612528
157Gout (HP:0001997)1.71531104
158Episodic fever (HP:0001954)1.71262592
159Abnormal foot bone ossification (HP:0010675)1.71029762
160Mesangial abnormality (HP:0001966)1.70479645
161Increased CSF protein (HP:0002922)1.70242787
162Protuberant abdomen (HP:0001538)1.69826965
163Decreased circulating renin level (HP:0003351)1.69449132
164Leukocytosis (HP:0001974)1.69365471
165Axonal loss (HP:0003447)1.68025185
166Back pain (HP:0003418)1.66682426
167Colitis (HP:0002583)1.66479947
168Cervical subluxation (HP:0003308)1.66118730

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB34.67672595
2ERN14.01516909
3PKN23.22871614
4RIPK43.16757747
5FGFR42.94322964
6SIK12.89209522
7MAP4K12.73322743
8EPHB12.22698966
9EEF2K2.19587454
10TYK22.12646319
11TTN2.08264420
12MAP3K102.04621218
13PTK61.98785774
14RIPK11.95730249
15PRPF4B1.92993498
16TNK21.73517021
17MAP3K31.66505196
18JAK31.63807524
19TGFBR21.62130148
20BCKDK1.58999178
21JAK11.58881669
22MAPK151.52194923
23TBK11.51771082
24LRRK21.51390266
25STK101.51262043
26CDC42BPA1.48511806
27TAOK21.47973457
28FGFR31.47227505
29ZAP701.46471320
30CDK121.45945480
31MAP2K31.38468521
32FES1.35925467
33MAP2K61.34617850
34MARK21.33803895
35MAP3K141.33672881
36GRK61.32591148
37PRKD21.31620158
38MST1R1.24597080
39LATS11.22688199
40CAMK1D1.22236218
41BMX1.18489333
42IRAK41.17739999
43ITK1.16177287
44EPHA31.14614301
45CAMK1G1.11638046
46MAP3K71.11513422
47TAOK31.10098014
48CSK1.08544528
49TAOK11.05919595
50IKBKE1.03759933
51PDGFRA1.03736407
52MAPK71.02358890
53JAK21.01850107
54FGFR20.97314942
55HIPK20.94613296
56CHUK0.91388501
57PTK20.89760182
58DAPK20.88854220
59HCK0.86557661
60NEK90.82828301
61BTK0.82576875
62RPS6KA20.82524284
63MTOR0.81347403
64CDK60.79460147
65IRAK30.79378499
66FLT30.77884828
67PRKCH0.77525394
68CAMKK10.77439004
69RPS6KA40.75843911
70LYN0.75378904
71FRK0.74793625
72IRAK10.74264182
73IKBKB0.72646799
74PDGFRB0.72558762
75RET0.72238391
76KSR20.70645858
77DMPK0.70511073
78STK380.69975550
79WNK10.69363104
80MAP3K130.68634472
81SIK30.68208342
82MAPK110.66400657
83PIM10.65476234
84TXK0.65194226
85FGFR10.64541461
86STK30.64018549
87FGR0.61740428
88PTK2B0.61051243
89BLK0.60555789
90EPHA20.60131674
91NLK0.59081719
92PIK3CG0.58643085
93CSF1R0.56969388
94SGK30.56787948
95MAP3K60.56740506
96MAP3K110.56553713
97TRPM70.55799199
98LCK0.55677546
99PAK20.55416227
100ICK0.55236347
101DDR20.54352436
102RPS6KA60.53190863
103STK110.53070218
104PRKD30.52901724
105RPS6KL10.52330869
106RPS6KC10.52330869
107TLK10.51800623
108TYRO30.50966160
109MARK30.50218779
110PDK10.50077343
111MAP3K10.49914224
112MAP3K20.48965290
113PRKG20.48351949
114MAPK120.47976621
115SYK0.47394631
116ACVR1B0.47110545
117PAK40.47083751
118PDPK10.46541700
119ADRBK20.46335839
120FYN0.46335365
121BMPR20.45432604
122PRKAA20.45367797
123CDK40.42994289
124MAPKAPK30.42707259
125ALK0.42180115
126KIT0.41775466
127DYRK1B0.40837402
128GSK3A0.39585655
129SIK20.37704076
130KDR0.37500029
131EGFR0.37089547
132PRKCQ0.37056857
133MAP3K80.36292306
134PRKD10.35533022
135MAP2K20.35212426
136STK240.34742620

Predicted pathways (KEGG)

RankGene SetZ-score
1Nitrogen metabolism_Homo sapiens_hsa009103.18072162
2Primary bile acid biosynthesis_Homo sapiens_hsa001203.07461890
3Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.86032892
4Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.61836036
5Complement and coagulation cascades_Homo sapiens_hsa046102.43404181
6Arginine biosynthesis_Homo sapiens_hsa002202.36211385
7Caffeine metabolism_Homo sapiens_hsa002322.28671236
8Staphylococcus aureus infection_Homo sapiens_hsa051502.27277473
9Other glycan degradation_Homo sapiens_hsa005112.23676692
10Fatty acid degradation_Homo sapiens_hsa000712.20071191
11PPAR signaling pathway_Homo sapiens_hsa033202.09123977
12Allograft rejection_Homo sapiens_hsa053301.90239636
13Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.84928811
14Tryptophan metabolism_Homo sapiens_hsa003801.83790383
15Graft-versus-host disease_Homo sapiens_hsa053321.83260183
16Autoimmune thyroid disease_Homo sapiens_hsa053201.79830175
17Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.79596176
18Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.74456369
19Fatty acid metabolism_Homo sapiens_hsa012121.66951779
20Pentose and glucuronate interconversions_Homo sapiens_hsa000401.58296998
21Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.50471441
22Asthma_Homo sapiens_hsa053101.49822416
232-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.42892377
24Bile secretion_Homo sapiens_hsa049761.36858668
25Fat digestion and absorption_Homo sapiens_hsa049751.35263360
26Propanoate metabolism_Homo sapiens_hsa006401.33619217
27Type I diabetes mellitus_Homo sapiens_hsa049401.32752670
28beta-Alanine metabolism_Homo sapiens_hsa004101.24144060
29Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.24018655
30Peroxisome_Homo sapiens_hsa041461.21489697
31Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.19545111
32Hematopoietic cell lineage_Homo sapiens_hsa046401.15687697
33Lysine degradation_Homo sapiens_hsa003101.14151161
34Histidine metabolism_Homo sapiens_hsa003401.14033022
35Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.09850788
36Chemical carcinogenesis_Homo sapiens_hsa052041.09295347
37Insulin resistance_Homo sapiens_hsa049311.08352236
38Fatty acid biosynthesis_Homo sapiens_hsa000611.07883971
39Butanoate metabolism_Homo sapiens_hsa006501.07480457
40Selenocompound metabolism_Homo sapiens_hsa004501.06951024
41Starch and sucrose metabolism_Homo sapiens_hsa005001.06739173
42Chemokine signaling pathway_Homo sapiens_hsa040621.06373028
43Adipocytokine signaling pathway_Homo sapiens_hsa049201.06365651
44ABC transporters_Homo sapiens_hsa020101.06193429
45Steroid hormone biosynthesis_Homo sapiens_hsa001401.05084427
46alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.04420771
47Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.03147751
48Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.03129147
49Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.98717165
50Drug metabolism - other enzymes_Homo sapiens_hsa009830.96640254
51Glycerolipid metabolism_Homo sapiens_hsa005610.96305815
52Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.95972998
53Linoleic acid metabolism_Homo sapiens_hsa005910.95391016
54Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.94719889
55Osteoclast differentiation_Homo sapiens_hsa043800.94116677
56Leishmaniasis_Homo sapiens_hsa051400.92468138
57Phenylalanine metabolism_Homo sapiens_hsa003600.92251932
58Vitamin digestion and absorption_Homo sapiens_hsa049770.90711537
59GnRH signaling pathway_Homo sapiens_hsa049120.88694384
60Retinol metabolism_Homo sapiens_hsa008300.88522783
61Dorso-ventral axis formation_Homo sapiens_hsa043200.87774849
62Carbon metabolism_Homo sapiens_hsa012000.86470577
63Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.86225857
64NOD-like receptor signaling pathway_Homo sapiens_hsa046210.85913288
65Toxoplasmosis_Homo sapiens_hsa051450.85335316
66Cyanoamino acid metabolism_Homo sapiens_hsa004600.83485923
67Platelet activation_Homo sapiens_hsa046110.82706580
68Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.82609537
69Phagosome_Homo sapiens_hsa041450.82519292
70Rheumatoid arthritis_Homo sapiens_hsa053230.82251146
71VEGF signaling pathway_Homo sapiens_hsa043700.81039353
72Phospholipase D signaling pathway_Homo sapiens_hsa040720.80762082
73Primary immunodeficiency_Homo sapiens_hsa053400.79683207
74Notch signaling pathway_Homo sapiens_hsa043300.79241978
75Pyruvate metabolism_Homo sapiens_hsa006200.79221999
76Biosynthesis of amino acids_Homo sapiens_hsa012300.77462103
77Glycerophospholipid metabolism_Homo sapiens_hsa005640.76744853
78Acute myeloid leukemia_Homo sapiens_hsa052210.75711335
79B cell receptor signaling pathway_Homo sapiens_hsa046620.75226550
80African trypanosomiasis_Homo sapiens_hsa051430.73989489
81Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.73933720
82Amoebiasis_Homo sapiens_hsa051460.71177785
83NF-kappa B signaling pathway_Homo sapiens_hsa040640.71017908
84Chronic myeloid leukemia_Homo sapiens_hsa052200.70368461
85Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.69336291
86Vascular smooth muscle contraction_Homo sapiens_hsa042700.68398661
87Choline metabolism in cancer_Homo sapiens_hsa052310.67482017
88Pentose phosphate pathway_Homo sapiens_hsa000300.67307920
89Aldosterone synthesis and secretion_Homo sapiens_hsa049250.66960471
90Renin-angiotensin system_Homo sapiens_hsa046140.66587729
91Neurotrophin signaling pathway_Homo sapiens_hsa047220.66512394
92Leukocyte transendothelial migration_Homo sapiens_hsa046700.66327338
93Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.65228487
94AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.64466630
95Arachidonic acid metabolism_Homo sapiens_hsa005900.63953658
96Ovarian steroidogenesis_Homo sapiens_hsa049130.63940741
97T cell receptor signaling pathway_Homo sapiens_hsa046600.62654131
98ECM-receptor interaction_Homo sapiens_hsa045120.62206162
99RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.60478027
100Tyrosine metabolism_Homo sapiens_hsa003500.60015380
101Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.59785254
102Estrogen signaling pathway_Homo sapiens_hsa049150.59611615
103Phosphatidylinositol signaling system_Homo sapiens_hsa040700.58496545
104Mineral absorption_Homo sapiens_hsa049780.58269712
105Toll-like receptor signaling pathway_Homo sapiens_hsa046200.57727028
106Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.57339624
107Lysosome_Homo sapiens_hsa041420.56327810
108Small cell lung cancer_Homo sapiens_hsa052220.56233188
109Measles_Homo sapiens_hsa051620.56083112
110TNF signaling pathway_Homo sapiens_hsa046680.54988488
111Focal adhesion_Homo sapiens_hsa045100.54534824
112Malaria_Homo sapiens_hsa051440.54478785
113Viral myocarditis_Homo sapiens_hsa054160.53021218
114mTOR signaling pathway_Homo sapiens_hsa041500.51938419
115Jak-STAT signaling pathway_Homo sapiens_hsa046300.51512303
116Sulfur relay system_Homo sapiens_hsa041220.51506601
117Proteoglycans in cancer_Homo sapiens_hsa052050.51467639
118Pancreatic cancer_Homo sapiens_hsa052120.51061491
119Hepatitis B_Homo sapiens_hsa051610.50640107
120Legionellosis_Homo sapiens_hsa051340.50602156
121Cysteine and methionine metabolism_Homo sapiens_hsa002700.50542029
122Sphingolipid metabolism_Homo sapiens_hsa006000.49958919
123Type II diabetes mellitus_Homo sapiens_hsa049300.49897182
124Sphingolipid signaling pathway_Homo sapiens_hsa040710.49692557
125Renal cell carcinoma_Homo sapiens_hsa052110.48980476
126Intestinal immune network for IgA production_Homo sapiens_hsa046720.47908389
127Endocytosis_Homo sapiens_hsa041440.47673960
128Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.47440551
129Antigen processing and presentation_Homo sapiens_hsa046120.47228761
130MAPK signaling pathway_Homo sapiens_hsa040100.47218316
131Protein digestion and absorption_Homo sapiens_hsa049740.46089288
132Ether lipid metabolism_Homo sapiens_hsa005650.45625375
133Hepatitis C_Homo sapiens_hsa051600.45622707
134Renin secretion_Homo sapiens_hsa049240.45090907
135Pertussis_Homo sapiens_hsa051330.45071115
136AMPK signaling pathway_Homo sapiens_hsa041520.44962710
137Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.44520592
138Folate biosynthesis_Homo sapiens_hsa007900.44479610
139Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.44459197
140Pancreatic secretion_Homo sapiens_hsa049720.44458546
141Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.44213658
142FoxO signaling pathway_Homo sapiens_hsa040680.43340860
143Glycosaminoglycan degradation_Homo sapiens_hsa005310.43045930
144Prolactin signaling pathway_Homo sapiens_hsa049170.42926127
145Fructose and mannose metabolism_Homo sapiens_hsa000510.42726722
146Tuberculosis_Homo sapiens_hsa051520.41827970
147Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.40844332
148Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.40117060
149Apoptosis_Homo sapiens_hsa042100.39163503
150Arginine and proline metabolism_Homo sapiens_hsa003300.38749644
151Influenza A_Homo sapiens_hsa051640.37927403
152Vitamin B6 metabolism_Homo sapiens_hsa007500.37633548
153Carbohydrate digestion and absorption_Homo sapiens_hsa049730.36742406
154Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.36275048
155Central carbon metabolism in cancer_Homo sapiens_hsa052300.35962194

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »