

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | response to peptidoglycan (GO:0032494) | 5.52640607 |
| 2 | neutrophil activation involved in immune response (GO:0002283) | 5.42199466 |
| 3 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 5.36821438 |
| 4 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 5.36821438 |
| 5 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 5.36821438 |
| 6 | modulation by symbiont of host immune response (GO:0052553) | 5.36821438 |
| 7 | positive regulation by symbiont of host defense response (GO:0052509) | 5.36821438 |
| 8 | modulation by symbiont of host defense response (GO:0052031) | 5.36821438 |
| 9 | negative regulation of interleukin-12 production (GO:0032695) | 5.17924622 |
| 10 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.15817336 |
| 11 | macrophage activation involved in immune response (GO:0002281) | 4.99417743 |
| 12 | negative regulation of cell killing (GO:0031342) | 4.91662342 |
| 13 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 4.91662342 |
| 14 | detection of other organism (GO:0098543) | 4.62411079 |
| 15 | detection of molecule of bacterial origin (GO:0032490) | 4.46466501 |
| 16 | detection of bacterium (GO:0016045) | 4.38186776 |
| 17 | immunoglobulin mediated immune response (GO:0016064) | 4.35993453 |
| 18 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.25752985 |
| 19 | detection of external biotic stimulus (GO:0098581) | 4.20331745 |
| 20 | regulation of mast cell degranulation (GO:0043304) | 4.04517598 |
| 21 | regulation of interferon-beta biosynthetic process (GO:0045357) | 4.02304825 |
| 22 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.99020729 |
| 23 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 3.97105749 |
| 24 | cellular extravasation (GO:0045123) | 3.85059700 |
| 25 | microglial cell activation (GO:0001774) | 3.82605259 |
| 26 | positive regulation of mast cell activation (GO:0033005) | 3.82008880 |
| 27 | detection of biotic stimulus (GO:0009595) | 3.73424336 |
| 28 | regulation of mast cell activation involved in immune response (GO:0033006) | 3.72184945 |
| 29 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 3.71164817 |
| 30 | myeloid cell activation involved in immune response (GO:0002275) | 3.69481321 |
| 31 | macrophage activation (GO:0042116) | 3.69174173 |
| 32 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.68622172 |
| 33 | respiratory burst (GO:0045730) | 3.68514964 |
| 34 | neutrophil activation (GO:0042119) | 3.68267891 |
| 35 | granulocyte activation (GO:0036230) | 3.66921346 |
| 36 | regulation of gamma-delta T cell activation (GO:0046643) | 3.65827860 |
| 37 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.62679053 |
| 38 | response to host immune response (GO:0052572) | 3.62679053 |
| 39 | leukocyte aggregation (GO:0070486) | 3.58672446 |
| 40 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.53877415 |
| 41 | regulation of mast cell activation (GO:0033003) | 3.52968033 |
| 42 | regulation of leukocyte degranulation (GO:0043300) | 3.51790006 |
| 43 | positive regulation of mast cell degranulation (GO:0043306) | 3.51179000 |
| 44 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 3.51179000 |
| 45 | response to muramyl dipeptide (GO:0032495) | 3.38775309 |
| 46 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.34050935 |
| 47 | positive regulation of antigen processing and presentation (GO:0002579) | 3.31632741 |
| 48 | leukocyte migration involved in inflammatory response (GO:0002523) | 3.30973060 |
| 49 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.30656466 |
| 50 | interferon-gamma-mediated signaling pathway (GO:0060333) | 3.30256057 |
| 51 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 3.29850631 |
| 52 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 3.25788785 |
| 53 | negative regulation of erythrocyte differentiation (GO:0045647) | 3.25662311 |
| 54 | cellular response to type I interferon (GO:0071357) | 3.25583286 |
| 55 | type I interferon signaling pathway (GO:0060337) | 3.25583286 |
| 56 | negative regulation of cytokine production involved in immune response (GO:0002719) | 3.25217294 |
| 57 | response to type I interferon (GO:0034340) | 3.24975519 |
| 58 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.21838095 |
| 59 | response to host (GO:0075136) | 3.21838095 |
| 60 | response to host defenses (GO:0052200) | 3.21838095 |
| 61 | B cell mediated immunity (GO:0019724) | 3.21426845 |
| 62 | regulation of interferon-alpha production (GO:0032647) | 3.17066522 |
| 63 | regulation of antigen processing and presentation (GO:0002577) | 3.16939001 |
| 64 | positive regulation of myeloid leukocyte mediated immunity (GO:0002888) | 3.16767298 |
| 65 | negative regulation of T cell mediated immunity (GO:0002710) | 3.15349172 |
| 66 | germinal center formation (GO:0002467) | 3.13804098 |
| 67 | defense response to protozoan (GO:0042832) | 3.12535689 |
| 68 | positive regulation of cellular amide metabolic process (GO:0034250) | 3.12259434 |
| 69 | positive regulation of interferon-alpha production (GO:0032727) | 3.09038366 |
| 70 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 3.07398112 |
| 71 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.06605644 |
| 72 | mannose metabolic process (GO:0006013) | 3.03954490 |
| 73 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.03949713 |
| 74 | amino sugar catabolic process (GO:0046348) | 2.97199469 |
| 75 | regulation of regulated secretory pathway (GO:1903305) | 2.93195032 |
| 76 | production of molecular mediator involved in inflammatory response (GO:0002532) | 2.92855904 |
| 77 | regulation of tolerance induction (GO:0002643) | 2.92706477 |
| 78 | regulation of T cell tolerance induction (GO:0002664) | 2.91377995 |
| 79 | response to protozoan (GO:0001562) | 2.86972865 |
| 80 | negative regulation of innate immune response (GO:0045824) | 2.83688512 |
| 81 | hydrogen peroxide biosynthetic process (GO:0050665) | 2.81550715 |
| 82 | regulation of T-helper 2 cell differentiation (GO:0045628) | 2.80830689 |
| 83 | leukocyte degranulation (GO:0043299) | 2.78630073 |
| 84 | positive regulation of toll-like receptor signaling pathway (GO:0034123) | 2.78621496 |
| 85 | negative regulation of interleukin-6 production (GO:0032715) | 2.78035937 |
| 86 | positive regulation of type 2 immune response (GO:0002830) | 2.77425234 |
| 87 | negative regulation of toll-like receptor signaling pathway (GO:0034122) | 2.77238695 |
| 88 | positive regulation of leukocyte degranulation (GO:0043302) | 2.76403110 |
| 89 | myeloid leukocyte activation (GO:0002274) | 2.76359129 |
| 90 | T-helper 1 type immune response (GO:0042088) | 2.73771917 |
| 91 | N-acetylneuraminate metabolic process (GO:0006054) | 2.71964129 |
| 92 | positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557) | 2.69203399 |
| 93 | neutrophil chemotaxis (GO:0030593) | 2.69059660 |
| 94 | regulation of gamma-delta T cell differentiation (GO:0045586) | 2.68344806 |
| 95 | regulation of toll-like receptor signaling pathway (GO:0034121) | 2.67893623 |
| 96 | regulation of interleukin-8 biosynthetic process (GO:0045414) | 2.67464172 |
| 97 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 2.66354566 |
| 98 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 2.66336877 |
| 99 | B cell receptor signaling pathway (GO:0050853) | 2.65388060 |
| 100 | neutrophil mediated immunity (GO:0002446) | 2.64916462 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.77258882 |
| 2 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 5.09833047 |
| 3 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 4.72501148 |
| 4 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 3.38656212 |
| 5 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.20007571 |
| 6 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.15424011 |
| 7 | VDR_21846776_ChIP-Seq_THP-1_Human | 3.11341282 |
| 8 | * VDR_24763502_ChIP-Seq_THP-1_Human | 2.79138919 |
| 9 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.78178994 |
| 10 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.64968166 |
| 11 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 2.60408369 |
| 12 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.58568938 |
| 13 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.40562474 |
| 14 | SPI1_23127762_ChIP-Seq_K562_Human | 2.35406271 |
| 15 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.33218055 |
| 16 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.19037683 |
| 17 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.17683040 |
| 18 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 2.11481050 |
| 19 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.10289102 |
| 20 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 2.05754050 |
| 21 | * MAF_26560356_Chip-Seq_TH1_Human | 2.00814103 |
| 22 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.00614586 |
| 23 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.00256950 |
| 24 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.96895583 |
| 25 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.96585222 |
| 26 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.94162724 |
| 27 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.90832518 |
| 28 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.87915481 |
| 29 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.85671729 |
| 30 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.83886702 |
| 31 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.82272940 |
| 32 | UTX_26944678_Chip-Seq_JUKART_Human | 1.78636715 |
| 33 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.77469434 |
| 34 | MAF_26560356_Chip-Seq_TH2_Human | 1.76993252 |
| 35 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.76052625 |
| 36 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.72710407 |
| 37 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.71334243 |
| 38 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.66637789 |
| 39 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.65581157 |
| 40 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.63829544 |
| 41 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.61551499 |
| 42 | MYB_26560356_Chip-Seq_TH2_Human | 1.61191735 |
| 43 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.58036110 |
| 44 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.53065428 |
| 45 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.51442839 |
| 46 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.49536552 |
| 47 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.48381514 |
| 48 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.45812782 |
| 49 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.45686004 |
| 50 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.44194435 |
| 51 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.42743794 |
| 52 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.42644152 |
| 53 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.41028426 |
| 54 | MYC_22102868_ChIP-Seq_BL_Human | 1.38490959 |
| 55 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.36672705 |
| 56 | MYB_26560356_Chip-Seq_TH1_Human | 1.36603561 |
| 57 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.36375406 |
| 58 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.35622156 |
| 59 | GATA1_22025678_ChIP-Seq_K562_Human | 1.35564863 |
| 60 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.30847874 |
| 61 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.30531511 |
| 62 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.29660950 |
| 63 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.28217883 |
| 64 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.27825821 |
| 65 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.23001416 |
| 66 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.21830351 |
| 67 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.21663180 |
| 68 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.20941267 |
| 69 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.19736319 |
| 70 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.19410858 |
| 71 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.17220404 |
| 72 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.15881075 |
| 73 | GATA1_19941826_ChIP-Seq_K562_Human | 1.14778851 |
| 74 | P68_20966046_ChIP-Seq_HELA_Human | 1.10479541 |
| 75 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.10299591 |
| 76 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.10298168 |
| 77 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.08346637 |
| 78 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.07505798 |
| 79 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.06845788 |
| 80 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.06371799 |
| 81 | GATA3_26560356_Chip-Seq_TH2_Human | 1.06350469 |
| 82 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.05507395 |
| 83 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.05126237 |
| 84 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.05088971 |
| 85 | * SPI1_20517297_ChIP-Seq_HL60_Human | 1.04970094 |
| 86 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.04663864 |
| 87 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.03057937 |
| 88 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.02083119 |
| 89 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.00703478 |
| 90 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.00667282 |
| 91 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.98634657 |
| 92 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.96635759 |
| 93 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 0.95835994 |
| 94 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.95371758 |
| 95 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.94207100 |
| 96 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 0.93997577 |
| 97 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 0.91569505 |
| 98 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 0.91326707 |
| 99 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 0.90277280 |
| 100 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 0.88116469 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003303_peritoneal_inflammation | 4.19959742 |
| 2 | MP0003724_increased_susceptibility_to | 4.16013946 |
| 3 | MP0003436_decreased_susceptibility_to | 3.70684086 |
| 4 | MP0001835_abnormal_antigen_presentation | 3.51741422 |
| 5 | MP0006082_CNS_inflammation | 3.38660594 |
| 6 | MP0005058_abnormal_lysosome_morphology | 3.14704418 |
| 7 | MP0002419_abnormal_innate_immunity | 3.13911510 |
| 8 | MP0009785_altered_susceptibility_to | 3.02435962 |
| 9 | MP0005671_abnormal_response_to | 2.85363039 |
| 10 | MP0005025_abnormal_response_to | 2.81846027 |
| 11 | MP0005387_immune_system_phenotype | 2.75029647 |
| 12 | MP0001790_abnormal_immune_system | 2.75029647 |
| 13 | MP0002148_abnormal_hypersensitivity_rea | 2.72110089 |
| 14 | MP0005000_abnormal_immune_tolerance | 2.62144656 |
| 15 | MP0003172_abnormal_lysosome_physiology | 2.51499954 |
| 16 | MP0001800_abnormal_humoral_immune | 2.43650808 |
| 17 | MP0000685_abnormal_immune_system | 2.38940847 |
| 18 | MP0002723_abnormal_immune_serum | 2.38520087 |
| 19 | MP0002452_abnormal_antigen_presenting | 2.35873039 |
| 20 | MP0002420_abnormal_adaptive_immunity | 2.14675909 |
| 21 | MP0001819_abnormal_immune_cell | 2.14450589 |
| 22 | MP0003806_abnormal_nucleotide_metabolis | 2.10073030 |
| 23 | MP0001986_abnormal_taste_sensitivity | 2.05228820 |
| 24 | MP0001533_abnormal_skeleton_physiology | 2.04072259 |
| 25 | MP0003300_gastrointestinal_ulcer | 2.00845022 |
| 26 | MP0005464_abnormal_platelet_physiology | 1.91937559 |
| 27 | MP0004510_myositis | 1.90846708 |
| 28 | MP0009840_abnormal_foam_cell | 1.84309448 |
| 29 | MP0001845_abnormal_inflammatory_respons | 1.81430378 |
| 30 | MP0009278_abnormal_bone_marrow | 1.81192763 |
| 31 | MP0003191_abnormal_cellular_cholesterol | 1.80518833 |
| 32 | MP0000343_altered_response_to | 1.75493606 |
| 33 | MP0002405_respiratory_system_inflammati | 1.73849569 |
| 34 | MP0003075_altered_response_to | 1.69433098 |
| 35 | MP0009764_decreased_sensitivity_to | 1.68718097 |
| 36 | MP0010155_abnormal_intestine_physiology | 1.64933783 |
| 37 | MP0008469_abnormal_protein_level | 1.63574267 |
| 38 | MP0002254_reproductive_system_inflammat | 1.62153672 |
| 39 | MP0003828_pulmonary_edema | 1.53832336 |
| 40 | MP0005397_hematopoietic_system_phenotyp | 1.53814333 |
| 41 | MP0001545_abnormal_hematopoietic_system | 1.53814333 |
| 42 | MP0000604_amyloidosis | 1.52101944 |
| 43 | MP0005310_abnormal_salivary_gland | 1.51843090 |
| 44 | MP0000716_abnormal_immune_system | 1.49023281 |
| 45 | MP0002998_abnormal_bone_remodeling | 1.46098034 |
| 46 | MP0008004_abnormal_stomach_pH | 1.39091772 |
| 47 | MP0009333_abnormal_splenocyte_physiolog | 1.37194385 |
| 48 | MP0003690_abnormal_glial_cell | 1.36138388 |
| 49 | MP0002398_abnormal_bone_marrow | 1.34568726 |
| 50 | MP0004947_skin_inflammation | 1.32008930 |
| 51 | MP0008260_abnormal_autophagy | 1.29146673 |
| 52 | MP0004883_abnormal_blood_vessel | 1.27213699 |
| 53 | MP0002132_abnormal_respiratory_system | 1.26986465 |
| 54 | MP0000465_gastrointestinal_hemorrhage | 1.25310947 |
| 55 | MP0005166_decreased_susceptibility_to | 1.24681886 |
| 56 | MP0000689_abnormal_spleen_morphology | 1.24672533 |
| 57 | MP0005174_abnormal_tail_pigmentation | 1.23761877 |
| 58 | MP0005167_abnormal_blood-brain_barrier | 1.19844437 |
| 59 | MP0002277_abnormal_respiratory_mucosa | 1.17138711 |
| 60 | MP0002429_abnormal_blood_cell | 1.13974643 |
| 61 | MP0002722_abnormal_immune_system | 1.12601468 |
| 62 | MP0000858_altered_metastatic_potential | 1.10433466 |
| 63 | MP0003448_altered_tumor_morphology | 1.08253081 |
| 64 | MP0003763_abnormal_thymus_physiology | 1.05495118 |
| 65 | MP0005451_abnormal_body_composition | 1.05045445 |
| 66 | MP0001853_heart_inflammation | 1.04690943 |
| 67 | MP0003866_abnormal_defecation | 1.01035577 |
| 68 | MP0002139_abnormal_hepatobiliary_system | 0.99939979 |
| 69 | MP0005164_abnormal_response_to | 0.96494435 |
| 70 | MP0001663_abnormal_digestive_system | 0.96372579 |
| 71 | MP0003656_abnormal_erythrocyte_physiolo | 0.95332433 |
| 72 | MP0006054_spinal_hemorrhage | 0.94559878 |
| 73 | MP0002138_abnormal_hepatobiliary_system | 0.87858860 |
| 74 | MP0003453_abnormal_keratinocyte_physiol | 0.85184669 |
| 75 | MP0004381_abnormal_hair_follicle | 0.81703184 |
| 76 | MP0003183_abnormal_peptide_metabolism | 0.81083506 |
| 77 | MP0001851_eye_inflammation | 0.80544717 |
| 78 | MP0000015_abnormal_ear_pigmentation | 0.76439692 |
| 79 | MP0001873_stomach_inflammation | 0.76146744 |
| 80 | MP0005083_abnormal_biliary_tract | 0.75102400 |
| 81 | MP0009763_increased_sensitivity_to | 0.74709834 |
| 82 | MP0000920_abnormal_myelination | 0.74113423 |
| 83 | MP0008874_decreased_physiological_sensi | 0.70919894 |
| 84 | MP0005390_skeleton_phenotype | 0.69868184 |
| 85 | MP0000703_abnormal_thymus_morphology | 0.69274662 |
| 86 | MP0004130_abnormal_muscle_cell | 0.68399294 |
| 87 | MP0005365_abnormal_bile_salt | 0.65724046 |
| 88 | MP0003329_amyloid_beta_deposits | 0.64681791 |
| 89 | MP0000490_abnormal_crypts_of | 0.63770247 |
| 90 | MP0003795_abnormal_bone_structure | 0.61266907 |
| 91 | MP0002332_abnormal_exercise_endurance | 0.60073259 |
| 92 | MP0003091_abnormal_cell_migration | 0.59967256 |
| 93 | MP0005319_abnormal_enzyme/_coenzyme | 0.57148351 |
| 94 | MP0002933_joint_inflammation | 0.56689710 |
| 95 | MP0000249_abnormal_blood_vessel | 0.54992090 |
| 96 | MP0005334_abnormal_fat_pad | 0.54012552 |
| 97 | MP0005076_abnormal_cell_differentiation | 0.53726102 |
| 98 | MP0002693_abnormal_pancreas_physiology | 0.53279868 |
| 99 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.51733878 |
| 100 | MP0001756_abnormal_urination | 0.51492923 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Recurrent abscess formation (HP:0002722) | 5.90068988 |
| 2 | Recurrent bacterial skin infections (HP:0005406) | 5.68171804 |
| 3 | Eczematoid dermatitis (HP:0000976) | 5.66019322 |
| 4 | Abnormality of macrophages (HP:0004311) | 5.55196721 |
| 5 | Abnormality of liposaccharide metabolism (HP:0010968) | 4.97256471 |
| 6 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 4.97256471 |
| 7 | Abnormality of glycolipid metabolism (HP:0010969) | 4.97256471 |
| 8 | Recurrent gram-negative bacterial infections (HP:0005420) | 4.84430937 |
| 9 | Myositis (HP:0100614) | 4.70668660 |
| 10 | Stomatitis (HP:0010280) | 4.48333906 |
| 11 | Orchitis (HP:0100796) | 4.46429775 |
| 12 | Optic neuritis (HP:0100653) | 4.32639912 |
| 13 | Retrobulbar optic neuritis (HP:0100654) | 4.32639912 |
| 14 | Increased cerebral lipofuscin (HP:0011813) | 4.16498130 |
| 15 | Obstructive lung disease (HP:0006536) | 3.93477547 |
| 16 | Chronic obstructive pulmonary disease (HP:0006510) | 3.93477547 |
| 17 | Mediastinal lymphadenopathy (HP:0100721) | 3.78190032 |
| 18 | Recurrent skin infections (HP:0001581) | 3.71508184 |
| 19 | Recurrent fungal infections (HP:0002841) | 3.56674919 |
| 20 | Systemic lupus erythematosus (HP:0002725) | 3.55464531 |
| 21 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 3.48319584 |
| 22 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.47010607 |
| 23 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.42719736 |
| 24 | Recurrent cutaneous fungal infections (HP:0011370) | 3.42719736 |
| 25 | Disinhibition (HP:0000734) | 3.37087491 |
| 26 | Spontaneous hematomas (HP:0007420) | 3.36891476 |
| 27 | Meningitis (HP:0001287) | 3.21919947 |
| 28 | Dysostosis multiplex (HP:0000943) | 3.20683367 |
| 29 | Vacuolated lymphocytes (HP:0001922) | 3.19987561 |
| 30 | Petechiae (HP:0000967) | 3.19887003 |
| 31 | Gastrointestinal infarctions (HP:0005244) | 3.14586786 |
| 32 | Purpura (HP:0000979) | 3.10117732 |
| 33 | Gingivitis (HP:0000230) | 3.06841941 |
| 34 | Loss of speech (HP:0002371) | 2.98544244 |
| 35 | Keratoconjunctivitis sicca (HP:0001097) | 2.96838548 |
| 36 | Encephalitis (HP:0002383) | 2.89142748 |
| 37 | Keratoconjunctivitis (HP:0001096) | 2.87898590 |
| 38 | Amyloidosis (HP:0011034) | 2.82201690 |
| 39 | Hemoptysis (HP:0002105) | 2.81739627 |
| 40 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.80653819 |
| 41 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.80653819 |
| 42 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.80653819 |
| 43 | Vasculitis (HP:0002633) | 2.78299112 |
| 44 | Urticaria (HP:0001025) | 2.74459163 |
| 45 | Chronic otitis media (HP:0000389) | 2.72636972 |
| 46 | Prolonged bleeding time (HP:0003010) | 2.71960643 |
| 47 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.70257744 |
| 48 | Mutism (HP:0002300) | 2.65300891 |
| 49 | Epistaxis (HP:0000421) | 2.60491428 |
| 50 | Autoimmune thrombocytopenia (HP:0001973) | 2.59783608 |
| 51 | Pulmonary infiltrates (HP:0002113) | 2.59245095 |
| 52 | Inflammation of the large intestine (HP:0002037) | 2.55080837 |
| 53 | Gingival bleeding (HP:0000225) | 2.50224095 |
| 54 | Mucopolysacchariduria (HP:0008155) | 2.49451399 |
| 55 | Urinary glycosaminoglycan excretion (HP:0003541) | 2.49451399 |
| 56 | Anorexia (HP:0002039) | 2.46477416 |
| 57 | Increased serum ferritin (HP:0003281) | 2.43183459 |
| 58 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 2.38872197 |
| 59 | Gastrointestinal inflammation (HP:0004386) | 2.38575596 |
| 60 | Recurrent viral infections (HP:0004429) | 2.36915605 |
| 61 | Chest pain (HP:0100749) | 2.32815125 |
| 62 | Arterial thrombosis (HP:0004420) | 2.32613072 |
| 63 | Glomerulonephritis (HP:0000099) | 2.32114064 |
| 64 | Cellulitis (HP:0100658) | 2.29211652 |
| 65 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 2.28777836 |
| 66 | Leukocytosis (HP:0001974) | 2.28620485 |
| 67 | Increased IgE level (HP:0003212) | 2.27332758 |
| 68 | Colitis (HP:0002583) | 2.27311249 |
| 69 | Episodic fever (HP:0001954) | 2.23138907 |
| 70 | Hematochezia (HP:0002573) | 2.22403586 |
| 71 | Pustule (HP:0200039) | 2.20618735 |
| 72 | Abnormality of iron homeostasis (HP:0011031) | 2.19330065 |
| 73 | Pulmonary embolism (HP:0002204) | 2.17777847 |
| 74 | Joint hemorrhage (HP:0005261) | 2.17446563 |
| 75 | Basal ganglia calcification (HP:0002135) | 2.17272936 |
| 76 | Osteomyelitis (HP:0002754) | 2.14606041 |
| 77 | Hypochromic anemia (HP:0001931) | 2.13924841 |
| 78 | Axonal loss (HP:0003447) | 2.12556356 |
| 79 | Polyneuropathy (HP:0001271) | 2.12509358 |
| 80 | Malnutrition (HP:0004395) | 2.09599982 |
| 81 | Increased IgM level (HP:0003496) | 2.08845645 |
| 82 | Cheilitis (HP:0100825) | 2.07147440 |
| 83 | Global brain atrophy (HP:0002283) | 2.00222746 |
| 84 | Inappropriate behavior (HP:0000719) | 1.99860195 |
| 85 | Hepatosplenomegaly (HP:0001433) | 1.96107896 |
| 86 | Upper motor neuron abnormality (HP:0002127) | 1.95802527 |
| 87 | T lymphocytopenia (HP:0005403) | 1.94885397 |
| 88 | Hypochromic microcytic anemia (HP:0004840) | 1.93823150 |
| 89 | Acne (HP:0001061) | 1.90721542 |
| 90 | Abnormality of T cell number (HP:0011839) | 1.90420224 |
| 91 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 1.87950291 |
| 92 | Vertigo (HP:0002321) | 1.86596633 |
| 93 | Asymmetric septal hypertrophy (HP:0001670) | 1.80865802 |
| 94 | Abnormality of transition element cation homeostasis (HP:0011030) | 1.80099232 |
| 95 | Abnormality of the endocardium (HP:0004306) | 1.79104859 |
| 96 | Neuronal loss in central nervous system (HP:0002529) | 1.78550443 |
| 97 | Gangrene (HP:0100758) | 1.77653925 |
| 98 | Agnosia (HP:0010524) | 1.77395559 |
| 99 | Memory impairment (HP:0002354) | 1.77295558 |
| 100 | Choroideremia (HP:0001139) | 1.77007478 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RIPK4 | 4.70987813 |
| 2 | BLK | 4.07507984 |
| 3 | MAP4K1 | 2.84380738 |
| 4 | TYK2 | 2.79479118 |
| 5 | MAP2K3 | 2.60152588 |
| 6 | IRAK4 | 2.54378326 |
| 7 | CSK | 2.48768278 |
| 8 | TESK2 | 2.38255015 |
| 9 | ERN1 | 2.16436507 |
| 10 | MAP3K13 | 2.08179567 |
| 11 | TNK2 | 2.04036529 |
| 12 | FES | 2.02241351 |
| 13 | FGR | 1.96713688 |
| 14 | PRPF4B | 1.91942809 |
| 15 | EPHB1 | 1.83393440 |
| 16 | ZAP70 | 1.82724876 |
| 17 | MAP3K14 | 1.82207928 |
| 18 | MAP3K3 | 1.79791220 |
| 19 | TAOK1 | 1.78498866 |
| 20 | TBK1 | 1.77608921 |
| 21 | MAP3K11 | 1.71341414 |
| 22 | SYK | 1.63568232 |
| 23 | JAK3 | 1.57770446 |
| 24 | BTK | 1.54796190 |
| 25 | IKBKE | 1.52538588 |
| 26 | TGFBR2 | 1.50899852 |
| 27 | GRK6 | 1.50602312 |
| 28 | TAOK2 | 1.49365190 |
| 29 | CSF1R | 1.48959431 |
| 30 | MARK3 | 1.46275911 |
| 31 | MATK | 1.36215269 |
| 32 | LYN | 1.34361397 |
| 33 | KIT | 1.34036231 |
| 34 | HCK | 1.31317414 |
| 35 | GRK7 | 1.30063334 |
| 36 | IKBKB | 1.28227078 |
| 37 | TXK | 1.23837231 |
| 38 | MAP3K1 | 1.22265365 |
| 39 | ACVR1B | 1.22012569 |
| 40 | PINK1 | 1.14055956 |
| 41 | JAK1 | 1.11549301 |
| 42 | JAK2 | 1.10695610 |
| 43 | MAPK15 | 1.10542633 |
| 44 | PDPK1 | 1.08413441 |
| 45 | TAOK3 | 1.06740857 |
| 46 | SIK3 | 0.98422705 |
| 47 | LCK | 0.97663764 |
| 48 | CAMKK2 | 0.97659407 |
| 49 | PDK1 | 0.97569943 |
| 50 | NME2 | 0.96127702 |
| 51 | CDC42BPA | 0.91450861 |
| 52 | IRAK3 | 0.90692413 |
| 53 | MOS | 0.87322307 |
| 54 | MARK2 | 0.85337191 |
| 55 | SIK2 | 0.85290020 |
| 56 | ADRBK2 | 0.83677462 |
| 57 | BMPR2 | 0.78183261 |
| 58 | ITK | 0.76962482 |
| 59 | TEC | 0.76577016 |
| 60 | DAPK2 | 0.73936009 |
| 61 | IRAK2 | 0.73782990 |
| 62 | MAPK12 | 0.73665700 |
| 63 | PRKD2 | 0.72621808 |
| 64 | KSR2 | 0.72533589 |
| 65 | MAP3K5 | 0.65934606 |
| 66 | MAPK7 | 0.63280018 |
| 67 | DYRK3 | 0.59079933 |
| 68 | CAMK1D | 0.58302543 |
| 69 | RIPK1 | 0.58090271 |
| 70 | RPS6KL1 | 0.57715563 |
| 71 | RPS6KC1 | 0.57715563 |
| 72 | RPS6KA6 | 0.56718622 |
| 73 | BRAF | 0.56481265 |
| 74 | RPS6KA2 | 0.56387752 |
| 75 | PRKCQ | 0.55776043 |
| 76 | SGK3 | 0.52384569 |
| 77 | YES1 | 0.51206136 |
| 78 | SGK2 | 0.50564455 |
| 79 | STK10 | 0.49755285 |
| 80 | MAP2K2 | 0.49731256 |
| 81 | MAP3K7 | 0.48951075 |
| 82 | FYN | 0.46742080 |
| 83 | DYRK1B | 0.41221566 |
| 84 | HIPK2 | 0.41058865 |
| 85 | IRAK1 | 0.40072568 |
| 86 | MAP2K6 | 0.37098040 |
| 87 | PTK6 | 0.36975522 |
| 88 | STK11 | 0.33981072 |
| 89 | SGK494 | 0.33392385 |
| 90 | SGK223 | 0.33392385 |
| 91 | KSR1 | 0.31381735 |
| 92 | STK38 | 0.31152007 |
| 93 | FRK | 0.30924649 |
| 94 | CHUK | 0.30743852 |
| 95 | TRIB3 | 0.28456596 |
| 96 | PRKG2 | 0.28182544 |
| 97 | MAP3K8 | 0.28121840 |
| 98 | ABL1 | 0.27814416 |
| 99 | CAMK4 | 0.26632346 |
| 100 | PRKAA2 | 0.26540513 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 3.41731209 |
| 2 | Osteoclast differentiation_Homo sapiens_hsa04380 | 3.07104355 |
| 3 | Other glycan degradation_Homo sapiens_hsa00511 | 3.03488066 |
| 4 | Leishmaniasis_Homo sapiens_hsa05140 | 2.95088298 |
| 5 | Allograft rejection_Homo sapiens_hsa05330 | 2.32411012 |
| 6 | Tuberculosis_Homo sapiens_hsa05152 | 2.30573113 |
| 7 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.28083560 |
| 8 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.16405205 |
| 9 | Lysosome_Homo sapiens_hsa04142 | 2.15912558 |
| 10 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.04375056 |
| 11 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 2.01588532 |
| 12 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.93214424 |
| 13 | Asthma_Homo sapiens_hsa05310 | 1.92936390 |
| 14 | Malaria_Homo sapiens_hsa05144 | 1.92782626 |
| 15 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.90632337 |
| 16 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.88560587 |
| 17 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.85626218 |
| 18 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.75761383 |
| 19 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.75513479 |
| 20 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.73076572 |
| 21 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.67873212 |
| 22 | Phagosome_Homo sapiens_hsa04145 | 1.63824793 |
| 23 | Legionellosis_Homo sapiens_hsa05134 | 1.63455618 |
| 24 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.59936407 |
| 25 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.57323149 |
| 26 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.57256621 |
| 27 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.56848787 |
| 28 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.54970414 |
| 29 | Pertussis_Homo sapiens_hsa05133 | 1.50318795 |
| 30 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.49368558 |
| 31 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.44761045 |
| 32 | Influenza A_Homo sapiens_hsa05164 | 1.43042611 |
| 33 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.42331918 |
| 34 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.37210584 |
| 35 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.33671910 |
| 36 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.32146307 |
| 37 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.32071459 |
| 38 | Measles_Homo sapiens_hsa05162 | 1.29712552 |
| 39 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.27188445 |
| 40 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.24959260 |
| 41 | Viral myocarditis_Homo sapiens_hsa05416 | 1.19391888 |
| 42 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.17040723 |
| 43 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.15540481 |
| 44 | Salmonella infection_Homo sapiens_hsa05132 | 1.11550760 |
| 45 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.08740097 |
| 46 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.07747114 |
| 47 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.99298602 |
| 48 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.97064656 |
| 49 | Platelet activation_Homo sapiens_hsa04611 | 0.94214246 |
| 50 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.92549200 |
| 51 | Hepatitis B_Homo sapiens_hsa05161 | 0.90045973 |
| 52 | Hepatitis C_Homo sapiens_hsa05160 | 0.88774276 |
| 53 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.79522559 |
| 54 | Apoptosis_Homo sapiens_hsa04210 | 0.77515304 |
| 55 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.73189773 |
| 56 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.71092691 |
| 57 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.69466936 |
| 58 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.67722394 |
| 59 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.67273790 |
| 60 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.64181677 |
| 61 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.64179676 |
| 62 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.63315919 |
| 63 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.62102162 |
| 64 | Endocytosis_Homo sapiens_hsa04144 | 0.61756068 |
| 65 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.59303810 |
| 66 | Shigellosis_Homo sapiens_hsa05131 | 0.58053671 |
| 67 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.56305405 |
| 68 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.55545406 |
| 69 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.54641717 |
| 70 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.53053232 |
| 71 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.52928406 |
| 72 | Amoebiasis_Homo sapiens_hsa05146 | 0.52222574 |
| 73 | Prion diseases_Homo sapiens_hsa05020 | 0.51911539 |
| 74 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.50971891 |
| 75 | Bladder cancer_Homo sapiens_hsa05219 | 0.50782369 |
| 76 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.44218414 |
| 77 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.43896965 |
| 78 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.43345379 |
| 79 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.42290078 |
| 80 | Insulin resistance_Homo sapiens_hsa04931 | 0.41763481 |
| 81 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.41674062 |
| 82 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.40506089 |
| 83 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.38512360 |
| 84 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.36677404 |
| 85 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.36415638 |
| 86 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.35505242 |
| 87 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.34603785 |
| 88 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.34261488 |
| 89 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.32654648 |
| 90 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.32346635 |
| 91 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.31784476 |
| 92 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.30718149 |
| 93 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.29585547 |
| 94 | Mineral absorption_Homo sapiens_hsa04978 | 0.29576434 |
| 95 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.26534484 |
| 96 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.26113097 |
| 97 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.25592609 |
| 98 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.24500737 |
| 99 | HTLV-I infection_Homo sapiens_hsa05166 | 0.24500599 |
| 100 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.22569497 |

