

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | neutrophil activation involved in immune response (GO:0002283) | 6.53182493 |
| 2 | immunoglobulin mediated immune response (GO:0016064) | 6.15925568 |
| 3 | response to peptidoglycan (GO:0032494) | 6.06077732 |
| 4 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.89145920 |
| 5 | cellular extravasation (GO:0045123) | 5.48851963 |
| 6 | positive regulation of mast cell activation (GO:0033005) | 5.30277915 |
| 7 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 5.12296970 |
| 8 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 5.12296970 |
| 9 | modulation by symbiont of host immune response (GO:0052553) | 5.12296970 |
| 10 | positive regulation by symbiont of host defense response (GO:0052509) | 5.12296970 |
| 11 | modulation by symbiont of host defense response (GO:0052031) | 5.12296970 |
| 12 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 5.12296970 |
| 13 | B cell mediated immunity (GO:0019724) | 5.01135144 |
| 14 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 4.95806786 |
| 15 | positive regulation of mast cell degranulation (GO:0043306) | 4.95806786 |
| 16 | regulation of mast cell degranulation (GO:0043304) | 4.84045626 |
| 17 | detection of other organism (GO:0098543) | 4.79554375 |
| 18 | detection of bacterium (GO:0016045) | 4.56565902 |
| 19 | macrophage activation involved in immune response (GO:0002281) | 4.52530939 |
| 20 | regulation of mast cell activation involved in immune response (GO:0033006) | 4.47583254 |
| 21 | microglial cell activation (GO:0001774) | 4.45568738 |
| 22 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 4.41954036 |
| 23 | regulation of mast cell activation (GO:0033003) | 4.40895105 |
| 24 | antigen processing and presentation of endogenous antigen (GO:0019883) | 4.31602940 |
| 25 | positive regulation of B cell differentiation (GO:0045579) | 4.30953695 |
| 26 | regulation of leukocyte degranulation (GO:0043300) | 4.26382220 |
| 27 | negative regulation of interleukin-12 production (GO:0032695) | 4.19312361 |
| 28 | neutrophil activation (GO:0042119) | 4.13412450 |
| 29 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 4.11620713 |
| 30 | regulation of gamma-delta T cell activation (GO:0046643) | 4.09455892 |
| 31 | respiratory burst (GO:0045730) | 4.06080949 |
| 32 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.04753584 |
| 33 | myeloid cell activation involved in immune response (GO:0002275) | 4.02970996 |
| 34 | detection of external biotic stimulus (GO:0098581) | 3.97121697 |
| 35 | negative regulation of cell killing (GO:0031342) | 3.88285060 |
| 36 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 3.88285060 |
| 37 | positive regulation of myeloid leukocyte mediated immunity (GO:0002888) | 3.88126764 |
| 38 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.85511163 |
| 39 | granulocyte activation (GO:0036230) | 3.85296177 |
| 40 | neutrophil mediated immunity (GO:0002446) | 3.85198334 |
| 41 | negative regulation of phagocytosis (GO:0050765) | 3.84574028 |
| 42 | response to host immune response (GO:0052572) | 3.80931232 |
| 43 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.80931232 |
| 44 | macrophage activation (GO:0042116) | 3.80506575 |
| 45 | positive thymic T cell selection (GO:0045059) | 3.79383611 |
| 46 | detection of molecule of bacterial origin (GO:0032490) | 3.75298213 |
| 47 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 3.74865366 |
| 48 | response to muramyl dipeptide (GO:0032495) | 3.73060649 |
| 49 | detection of biotic stimulus (GO:0009595) | 3.70505141 |
| 50 | regulation of antigen processing and presentation (GO:0002577) | 3.67885812 |
| 51 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 3.67335104 |
| 52 | positive regulation of antigen processing and presentation (GO:0002579) | 3.65697681 |
| 53 | regulation of hypersensitivity (GO:0002883) | 3.63061451 |
| 54 | regulation of B cell differentiation (GO:0045577) | 3.60416181 |
| 55 | regulation of regulated secretory pathway (GO:1903305) | 3.57377152 |
| 56 | interferon-gamma-mediated signaling pathway (GO:0060333) | 3.56903342 |
| 57 | negative regulation of erythrocyte differentiation (GO:0045647) | 3.56188721 |
| 58 | positive regulation of leukocyte degranulation (GO:0043302) | 3.55685481 |
| 59 | cell wall macromolecule catabolic process (GO:0016998) | 3.50674105 |
| 60 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 3.47389435 |
| 61 | response to host (GO:0075136) | 3.43728502 |
| 62 | response to host defenses (GO:0052200) | 3.43728502 |
| 63 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.43728502 |
| 64 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 3.42746659 |
| 65 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.40579697 |
| 66 | regulation of macrophage cytokine production (GO:0010935) | 3.33258136 |
| 67 | mature B cell differentiation involved in immune response (GO:0002313) | 3.27366727 |
| 68 | positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:0061081 | 3.26890570 |
| 69 | modulation of growth of symbiont involved in interaction with host (GO:0044144) | 3.24343378 |
| 70 | regulation of growth of symbiont in host (GO:0044126) | 3.24343378 |
| 71 | negative regulation of growth of symbiont in host (GO:0044130) | 3.24343378 |
| 72 | negative regulation of growth of symbiont involved in interaction with host (GO:0044146) | 3.24343378 |
| 73 | defense response to protozoan (GO:0042832) | 3.23155227 |
| 74 | positive regulation of macrophage cytokine production (GO:0060907) | 3.22802152 |
| 75 | B cell receptor signaling pathway (GO:0050853) | 3.21927572 |
| 76 | negative regulation of T cell mediated immunity (GO:0002710) | 3.17718722 |
| 77 | leukocyte degranulation (GO:0043299) | 3.14753571 |
| 78 | positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557) | 3.14034774 |
| 79 | myeloid leukocyte mediated immunity (GO:0002444) | 3.10941773 |
| 80 | positive regulation of regulated secretory pathway (GO:1903307) | 3.08984410 |
| 81 | leukocyte aggregation (GO:0070486) | 3.05907484 |
| 82 | pinocytosis (GO:0006907) | 3.05369651 |
| 83 | response to protozoan (GO:0001562) | 3.03565936 |
| 84 | positive regulation of type 2 immune response (GO:0002830) | 3.02316347 |
| 85 | negative thymic T cell selection (GO:0045060) | 3.00175851 |
| 86 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 2.97268200 |
| 87 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 2.94923891 |
| 88 | cell wall macromolecule metabolic process (GO:0044036) | 2.92379048 |
| 89 | positive regulation of tumor necrosis factor production (GO:0032760) | 2.91999407 |
| 90 | T cell selection (GO:0045058) | 2.91554376 |
| 91 | regulation of interferon-beta biosynthetic process (GO:0045357) | 2.90347815 |
| 92 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.89445445 |
| 93 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 2.87419902 |
| 94 | T-helper 1 type immune response (GO:0042088) | 2.86839098 |
| 95 | myeloid leukocyte activation (GO:0002274) | 2.85532846 |
| 96 | mast cell activation (GO:0045576) | 2.85448773 |
| 97 | regulation of interleukin-8 biosynthetic process (GO:0045414) | 2.85361509 |
| 98 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 2.85336638 |
| 99 | positive T cell selection (GO:0043368) | 2.82047309 |
| 100 | regulation of T-helper 2 cell differentiation (GO:0045628) | 2.81877813 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 6.40927025 |
| 2 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 6.29571058 |
| 3 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 4.36339339 |
| 4 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.70900807 |
| 5 | VDR_21846776_ChIP-Seq_THP-1_Human | 3.61082232 |
| 6 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 3.44748193 |
| 7 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.28436716 |
| 8 | VDR_24763502_ChIP-Seq_THP-1_Human | 3.24094932 |
| 9 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 3.23536006 |
| 10 | SPI1_23547873_ChIP-Seq_NB4_Human | 3.12070316 |
| 11 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.95187384 |
| 12 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.93972426 |
| 13 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.75926660 |
| 14 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.75490151 |
| 15 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.74452268 |
| 16 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.72015704 |
| 17 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 2.70420382 |
| 18 | SPI1_23127762_ChIP-Seq_K562_Human | 2.68454517 |
| 19 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.58085832 |
| 20 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.50049833 |
| 21 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.27123681 |
| 22 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 2.24210436 |
| 23 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.23758726 |
| 24 | MYB_26560356_Chip-Seq_TH2_Human | 2.22199630 |
| 25 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 2.19097671 |
| 26 | MAF_26560356_Chip-Seq_TH1_Human | 2.13510224 |
| 27 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.10676274 |
| 28 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.09269896 |
| 29 | VDR_24787735_ChIP-Seq_THP-1_Human | 2.04826854 |
| 30 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 2.03506597 |
| 31 | UTX_26944678_Chip-Seq_JUKART_Human | 2.01778504 |
| 32 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.00936598 |
| 33 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.98618126 |
| 34 | MYC_22102868_ChIP-Seq_BL_Human | 1.98459511 |
| 35 | MYB_26560356_Chip-Seq_TH1_Human | 1.92887232 |
| 36 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.91530468 |
| 37 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.90033985 |
| 38 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.86940555 |
| 39 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.86769926 |
| 40 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.80091962 |
| 41 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.76597088 |
| 42 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.69064590 |
| 43 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.68491896 |
| 44 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.58367809 |
| 45 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.53375490 |
| 46 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.53098231 |
| 47 | MAF_26560356_Chip-Seq_TH2_Human | 1.49909890 |
| 48 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.45918116 |
| 49 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.41788048 |
| 50 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.39789467 |
| 51 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.37022450 |
| 52 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.36390910 |
| 53 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.34970900 |
| 54 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.33410222 |
| 55 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.33035305 |
| 56 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.32524215 |
| 57 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.32052235 |
| 58 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.31466044 |
| 59 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.30904809 |
| 60 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.29182180 |
| 61 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.28662862 |
| 62 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.28088651 |
| 63 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.28048712 |
| 64 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.27914744 |
| 65 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.27652681 |
| 66 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.27281617 |
| 67 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.26859214 |
| 68 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.22715480 |
| 69 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.22485691 |
| 70 | GATA3_26560356_Chip-Seq_TH2_Human | 1.20208248 |
| 71 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.15254400 |
| 72 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.13888976 |
| 73 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.13861083 |
| 74 | SPI1_20517297_ChIP-Seq_HL60_Human | 1.13260984 |
| 75 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.13127112 |
| 76 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.12957052 |
| 77 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.12808829 |
| 78 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.12528141 |
| 79 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.12458774 |
| 80 | RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.08770982 |
| 81 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.08509048 |
| 82 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.06180382 |
| 83 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.06044943 |
| 84 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.05972058 |
| 85 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.02794449 |
| 86 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.01978892 |
| 87 | GATA1_19941826_ChIP-Seq_K562_Human | 0.99376544 |
| 88 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.97446698 |
| 89 | GATA1_22025678_ChIP-Seq_K562_Human | 0.96572407 |
| 90 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.91429194 |
| 91 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 0.88972870 |
| 92 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.87986176 |
| 93 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 0.85964881 |
| 94 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 0.85546276 |
| 95 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.85174242 |
| 96 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.84322667 |
| 97 | NCOR1_26117541_ChIP-Seq_K562_Human | 0.81836126 |
| 98 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.81493773 |
| 99 | P300_27268052_Chip-Seq_Bcells_Human | 0.77558469 |
| 100 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.75165598 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001835_abnormal_antigen_presentation | 4.71471954 |
| 2 | MP0003724_increased_susceptibility_to | 3.86541713 |
| 3 | MP0003436_decreased_susceptibility_to | 3.70725435 |
| 4 | MP0002419_abnormal_innate_immunity | 3.34522595 |
| 5 | MP0003303_peritoneal_inflammation | 3.11889163 |
| 6 | MP0005058_abnormal_lysosome_morphology | 2.92784912 |
| 7 | MP0005025_abnormal_response_to | 2.89824363 |
| 8 | MP0006082_CNS_inflammation | 2.87935287 |
| 9 | MP0003172_abnormal_lysosome_physiology | 2.76353643 |
| 10 | MP0002148_abnormal_hypersensitivity_rea | 2.74168036 |
| 11 | MP0005000_abnormal_immune_tolerance | 2.72317543 |
| 12 | MP0001800_abnormal_humoral_immune | 2.71691073 |
| 13 | MP0005464_abnormal_platelet_physiology | 2.68673847 |
| 14 | MP0009785_altered_susceptibility_to | 2.57984640 |
| 15 | MP0005671_abnormal_response_to | 2.57508288 |
| 16 | MP0002452_abnormal_antigen_presenting | 2.53864764 |
| 17 | MP0002420_abnormal_adaptive_immunity | 2.48070456 |
| 18 | MP0001819_abnormal_immune_cell | 2.45039547 |
| 19 | MP0002723_abnormal_immune_serum | 2.44759805 |
| 20 | MP0001790_abnormal_immune_system | 2.37016392 |
| 21 | MP0005387_immune_system_phenotype | 2.37016392 |
| 22 | MP0003828_pulmonary_edema | 2.34705139 |
| 23 | MP0000685_abnormal_immune_system | 2.28197297 |
| 24 | MP0008260_abnormal_autophagy | 2.18690011 |
| 25 | MP0002132_abnormal_respiratory_system | 2.17020588 |
| 26 | MP0003806_abnormal_nucleotide_metabolis | 2.06691042 |
| 27 | MP0009278_abnormal_bone_marrow | 2.00610454 |
| 28 | MP0002396_abnormal_hematopoietic_system | 1.85947079 |
| 29 | MP0002398_abnormal_bone_marrow | 1.85506767 |
| 30 | MP0001533_abnormal_skeleton_physiology | 1.84428349 |
| 31 | MP0003300_gastrointestinal_ulcer | 1.83610616 |
| 32 | MP0003075_altered_response_to | 1.81624726 |
| 33 | MP0000716_abnormal_immune_system | 1.81624232 |
| 34 | MP0002166_altered_tumor_susceptibility | 1.76303161 |
| 35 | MP0002009_preneoplasia | 1.73188835 |
| 36 | MP0002405_respiratory_system_inflammati | 1.73104805 |
| 37 | MP0005451_abnormal_body_composition | 1.69320638 |
| 38 | MP0001545_abnormal_hematopoietic_system | 1.69168222 |
| 39 | MP0005397_hematopoietic_system_phenotyp | 1.69168222 |
| 40 | MP0001853_heart_inflammation | 1.68692870 |
| 41 | MP0000465_gastrointestinal_hemorrhage | 1.68451090 |
| 42 | MP0009764_decreased_sensitivity_to | 1.67912396 |
| 43 | MP0001845_abnormal_inflammatory_respons | 1.67087670 |
| 44 | MP0000858_altered_metastatic_potential | 1.58495823 |
| 45 | MP0003763_abnormal_thymus_physiology | 1.56296985 |
| 46 | MP0000689_abnormal_spleen_morphology | 1.55026705 |
| 47 | MP0002722_abnormal_immune_system | 1.54418651 |
| 48 | MP0008469_abnormal_protein_level | 1.53213143 |
| 49 | MP0010155_abnormal_intestine_physiology | 1.51028038 |
| 50 | MP0002429_abnormal_blood_cell | 1.50772224 |
| 51 | MP0008004_abnormal_stomach_pH | 1.47849963 |
| 52 | MP0003191_abnormal_cellular_cholesterol | 1.46809129 |
| 53 | MP0005166_decreased_susceptibility_to | 1.41809885 |
| 54 | MP0002998_abnormal_bone_remodeling | 1.41508503 |
| 55 | MP0004883_abnormal_blood_vessel | 1.33878791 |
| 56 | MP0004947_skin_inflammation | 1.29141385 |
| 57 | MP0003866_abnormal_defecation | 1.28134488 |
| 58 | MP0000703_abnormal_thymus_morphology | 1.16254229 |
| 59 | MP0000343_altered_response_to | 1.13431197 |
| 60 | MP0009333_abnormal_splenocyte_physiolog | 1.13364346 |
| 61 | MP0002006_tumorigenesis | 1.13114735 |
| 62 | MP0003183_abnormal_peptide_metabolism | 1.11069262 |
| 63 | MP0001851_eye_inflammation | 1.08711460 |
| 64 | MP0009763_increased_sensitivity_to | 0.97539433 |
| 65 | MP0005164_abnormal_response_to | 0.95427353 |
| 66 | MP0001986_abnormal_taste_sensitivity | 0.93566284 |
| 67 | MP0004808_abnormal_hematopoietic_stem | 0.93455949 |
| 68 | MP0003690_abnormal_glial_cell | 0.89071651 |
| 69 | MP0000604_amyloidosis | 0.88949021 |
| 70 | MP0000015_abnormal_ear_pigmentation | 0.88681156 |
| 71 | MP0005075_abnormal_melanosome_morpholog | 0.88288535 |
| 72 | MP0005390_skeleton_phenotype | 0.82801657 |
| 73 | MP0000569_abnormal_digit_pigmentation | 0.82582827 |
| 74 | MP0006036_abnormal_mitochondrial_physio | 0.82385990 |
| 75 | MP0003656_abnormal_erythrocyte_physiolo | 0.82323117 |
| 76 | MP0003448_altered_tumor_morphology | 0.82155533 |
| 77 | MP0004510_myositis | 0.81377633 |
| 78 | MP0005319_abnormal_enzyme/_coenzyme | 0.72993163 |
| 79 | MP0004381_abnormal_hair_follicle | 0.71768986 |
| 80 | MP0005165_increased_susceptibility_to | 0.70441497 |
| 81 | MP0009840_abnormal_foam_cell | 0.70236406 |
| 82 | MP0005174_abnormal_tail_pigmentation | 0.69529791 |
| 83 | MP0001663_abnormal_digestive_system | 0.68810538 |
| 84 | MP0005310_abnormal_salivary_gland | 0.68747982 |
| 85 | MP0002019_abnormal_tumor_incidence | 0.68177620 |
| 86 | MP0000490_abnormal_crypts_of | 0.65531025 |
| 87 | MP0001873_stomach_inflammation | 0.64073845 |
| 88 | MP0000249_abnormal_blood_vessel | 0.63241100 |
| 89 | MP0003795_abnormal_bone_structure | 0.61562499 |
| 90 | MP0009765_abnormal_xenobiotic_induced | 0.60929925 |
| 91 | MP0005647_abnormal_sex_gland | 0.60571558 |
| 92 | MP0000920_abnormal_myelination | 0.58887977 |
| 93 | MP0002933_joint_inflammation | 0.51860110 |
| 94 | MP0005076_abnormal_cell_differentiation | 0.49301595 |
| 95 | MP0005376_homeostasis/metabolism_phenot | 0.48856594 |
| 96 | MP0005084_abnormal_gallbladder_morpholo | 0.48755334 |
| 97 | MP0008873_increased_physiological_sensi | 0.48474172 |
| 98 | MP0005334_abnormal_fat_pad | 0.47697661 |
| 99 | MP0009115_abnormal_fat_cell | 0.46926225 |
| 100 | MP0000470_abnormal_stomach_morphology | 0.45475980 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Recurrent abscess formation (HP:0002722) | 5.94325217 |
| 2 | Recurrent bacterial skin infections (HP:0005406) | 5.88790274 |
| 3 | Eczematoid dermatitis (HP:0000976) | 5.10867299 |
| 4 | Abnormality of macrophages (HP:0004311) | 5.02802064 |
| 5 | Obstructive lung disease (HP:0006536) | 4.76565738 |
| 6 | Chronic obstructive pulmonary disease (HP:0006510) | 4.76565738 |
| 7 | Increased cerebral lipofuscin (HP:0011813) | 4.59349428 |
| 8 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.58372124 |
| 9 | Recurrent gram-negative bacterial infections (HP:0005420) | 4.48979063 |
| 10 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 4.30610104 |
| 11 | Amyloidosis (HP:0011034) | 4.29965657 |
| 12 | Myositis (HP:0100614) | 4.23706434 |
| 13 | Recurrent skin infections (HP:0001581) | 4.13361574 |
| 14 | Recurrent cutaneous fungal infections (HP:0011370) | 4.11363283 |
| 15 | Chronic mucocutaneous candidiasis (HP:0002728) | 4.11363283 |
| 16 | Meningitis (HP:0001287) | 4.10579561 |
| 17 | Stomatitis (HP:0010280) | 3.94922346 |
| 18 | Recurrent fungal infections (HP:0002841) | 3.94872785 |
| 19 | Mediastinal lymphadenopathy (HP:0100721) | 3.89449872 |
| 20 | Abnormality of liposaccharide metabolism (HP:0010968) | 3.75859010 |
| 21 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 3.75859010 |
| 22 | Abnormality of glycolipid metabolism (HP:0010969) | 3.75859010 |
| 23 | Chest pain (HP:0100749) | 3.63723590 |
| 24 | Orchitis (HP:0100796) | 3.55269725 |
| 25 | Urticaria (HP:0001025) | 3.37422344 |
| 26 | Abnormality of the prostate (HP:0008775) | 3.36699637 |
| 27 | Hemoptysis (HP:0002105) | 3.36639982 |
| 28 | Retrobulbar optic neuritis (HP:0100654) | 3.34332064 |
| 29 | Optic neuritis (HP:0100653) | 3.34332064 |
| 30 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.29586142 |
| 31 | Thrombocytosis (HP:0001894) | 3.28090772 |
| 32 | Epistaxis (HP:0000421) | 3.22302524 |
| 33 | Pulmonary infiltrates (HP:0002113) | 3.22293520 |
| 34 | Vasculitis (HP:0002633) | 3.18524049 |
| 35 | Petechiae (HP:0000967) | 3.16917483 |
| 36 | Prolonged bleeding time (HP:0003010) | 3.16824731 |
| 37 | Gastrointestinal infarctions (HP:0005244) | 3.11478762 |
| 38 | Granulocytopenia (HP:0001913) | 3.10096297 |
| 39 | Encephalitis (HP:0002383) | 3.00937060 |
| 40 | Panhypogammaglobulinemia (HP:0003139) | 2.97030246 |
| 41 | Gingival bleeding (HP:0000225) | 2.92052933 |
| 42 | Agammaglobulinemia (HP:0004432) | 2.89595130 |
| 43 | Recurrent viral infections (HP:0004429) | 2.83481918 |
| 44 | Gingivitis (HP:0000230) | 2.83418498 |
| 45 | Spontaneous hematomas (HP:0007420) | 2.83170318 |
| 46 | Leukocytosis (HP:0001974) | 2.77502385 |
| 47 | Colitis (HP:0002583) | 2.77387163 |
| 48 | Cellulitis (HP:0100658) | 2.76947191 |
| 49 | Inflammation of the large intestine (HP:0002037) | 2.74280445 |
| 50 | Gastrointestinal inflammation (HP:0004386) | 2.70117464 |
| 51 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 2.66465527 |
| 52 | Dysostosis multiplex (HP:0000943) | 2.66263039 |
| 53 | Abnormality of the pleura (HP:0002103) | 2.61998121 |
| 54 | Gangrene (HP:0100758) | 2.59192370 |
| 55 | Purpura (HP:0000979) | 2.59092463 |
| 56 | Pulmonary embolism (HP:0002204) | 2.57606096 |
| 57 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 2.50419714 |
| 58 | Skin rash (HP:0000988) | 2.48623347 |
| 59 | Keratoconjunctivitis sicca (HP:0001097) | 2.45720970 |
| 60 | Arterial thrombosis (HP:0004420) | 2.44114316 |
| 61 | Fatigue (HP:0012378) | 2.43805098 |
| 62 | Osteomyelitis (HP:0002754) | 2.40932107 |
| 63 | Polyneuropathy (HP:0001271) | 2.39958158 |
| 64 | Increased serum ferritin (HP:0003281) | 2.39157932 |
| 65 | Eosinophilia (HP:0001880) | 2.38316791 |
| 66 | Increased IgE level (HP:0003212) | 2.38165023 |
| 67 | Loss of speech (HP:0002371) | 2.37562352 |
| 68 | Hepatosplenomegaly (HP:0001433) | 2.35173382 |
| 69 | Vacuolated lymphocytes (HP:0001922) | 2.30807141 |
| 70 | Keratoconjunctivitis (HP:0001096) | 2.28595469 |
| 71 | Amaurosis fugax (HP:0100576) | 2.24481619 |
| 72 | Thoracic kyphosis (HP:0002942) | 2.21796089 |
| 73 | Episodic fever (HP:0001954) | 2.21031813 |
| 74 | Polygenic inheritance (HP:0010982) | 2.19624182 |
| 75 | Skin ulcer (HP:0200042) | 2.17156755 |
| 76 | Increased IgM level (HP:0003496) | 2.16046958 |
| 77 | Abnormality of male internal genitalia (HP:0000022) | 2.15029188 |
| 78 | Abnormality of T cell physiology (HP:0011840) | 2.11882371 |
| 79 | Restrictive lung disease (HP:0002091) | 2.11315427 |
| 80 | Thrombophlebitis (HP:0004418) | 2.11113448 |
| 81 | Glomerulopathy (HP:0100820) | 2.10308088 |
| 82 | Abnormality of T cells (HP:0002843) | 2.08683590 |
| 83 | Mutism (HP:0002300) | 2.03198386 |
| 84 | Abnormality of the columella (HP:0009929) | 2.03084483 |
| 85 | Ureteral stenosis (HP:0000071) | 2.03054247 |
| 86 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.02876637 |
| 87 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.02876637 |
| 88 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.02876637 |
| 89 | Pulmonary fibrosis (HP:0002206) | 2.02355920 |
| 90 | Abnormality of iron homeostasis (HP:0011031) | 2.01938972 |
| 91 | Basal ganglia calcification (HP:0002135) | 2.01271529 |
| 92 | Autoimmune thrombocytopenia (HP:0001973) | 2.01228404 |
| 93 | Sepsis (HP:0100806) | 1.99758885 |
| 94 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 1.99176722 |
| 95 | Pustule (HP:0200039) | 1.96593311 |
| 96 | Ureteral obstruction (HP:0006000) | 1.96473409 |
| 97 | Vertigo (HP:0002321) | 1.95489742 |
| 98 | Abnormality of the peritoneum (HP:0002585) | 1.94536094 |
| 99 | Anorexia (HP:0002039) | 1.94386600 |
| 100 | Cerebral ischemia (HP:0002637) | 1.92497057 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RIPK4 | 5.22499231 |
| 2 | BLK | 3.77073031 |
| 3 | FES | 3.16918586 |
| 4 | MAP4K1 | 2.97877896 |
| 5 | TYK2 | 2.90239859 |
| 6 | MAP2K3 | 2.61677860 |
| 7 | KIT | 2.53237265 |
| 8 | IRAK4 | 2.47178746 |
| 9 | ERN1 | 2.46871524 |
| 10 | BMPR2 | 2.35941497 |
| 11 | CSF1R | 2.32704732 |
| 12 | MAP3K14 | 2.28984174 |
| 13 | BTK | 2.23496323 |
| 14 | ZAP70 | 2.14862858 |
| 15 | SYK | 2.13866550 |
| 16 | TNK2 | 2.07161231 |
| 17 | CSK | 1.96542397 |
| 18 | PRPF4B | 1.92185816 |
| 19 | JAK3 | 1.83530059 |
| 20 | GRK6 | 1.79308934 |
| 21 | TESK2 | 1.74234124 |
| 22 | TEC | 1.67356008 |
| 23 | HCK | 1.61312345 |
| 24 | TBK1 | 1.58684848 |
| 25 | LYN | 1.53980489 |
| 26 | MAP3K13 | 1.52421571 |
| 27 | TXK | 1.50438864 |
| 28 | IKBKE | 1.46662998 |
| 29 | PIK3CG | 1.45196238 |
| 30 | FGR | 1.43663767 |
| 31 | MARK3 | 1.38670768 |
| 32 | MAP3K3 | 1.37631421 |
| 33 | FLT3 | 1.35595734 |
| 34 | KDR | 1.31533435 |
| 35 | RPS6KA4 | 1.30836250 |
| 36 | JAK2 | 1.21052430 |
| 37 | LCK | 1.20618014 |
| 38 | TAOK3 | 1.16162145 |
| 39 | MAPK12 | 1.14014292 |
| 40 | MAP3K11 | 1.12405113 |
| 41 | ITK | 1.12314546 |
| 42 | MATK | 1.11274780 |
| 43 | JAK1 | 1.04603467 |
| 44 | MAP3K1 | 1.04521947 |
| 45 | IKBKB | 1.01992046 |
| 46 | PINK1 | 0.93130543 |
| 47 | IRAK2 | 0.87662860 |
| 48 | MOS | 0.84842742 |
| 49 | PDK1 | 0.82889077 |
| 50 | MAPK7 | 0.82261928 |
| 51 | PDPK1 | 0.77847993 |
| 52 | CDK19 | 0.75534821 |
| 53 | PRKCQ | 0.73515099 |
| 54 | RPS6KL1 | 0.73177647 |
| 55 | RPS6KC1 | 0.73177647 |
| 56 | NME2 | 0.72059824 |
| 57 | YES1 | 0.66366793 |
| 58 | STK10 | 0.66176559 |
| 59 | ARAF | 0.61339650 |
| 60 | RPS6KA6 | 0.60792790 |
| 61 | MAP3K5 | 0.60021439 |
| 62 | MAP3K7 | 0.57356126 |
| 63 | GRK7 | 0.57290674 |
| 64 | TRPM7 | 0.55646838 |
| 65 | MAP3K6 | 0.55386010 |
| 66 | TAOK1 | 0.54345381 |
| 67 | RPS6KA2 | 0.50346291 |
| 68 | CDK6 | 0.49874485 |
| 69 | TGFBR2 | 0.49039734 |
| 70 | MAP2K2 | 0.48378019 |
| 71 | KSR2 | 0.46391237 |
| 72 | IRAK3 | 0.45542347 |
| 73 | TAOK2 | 0.44783443 |
| 74 | LRRK2 | 0.42946052 |
| 75 | FYN | 0.42077976 |
| 76 | IRAK1 | 0.41826387 |
| 77 | ABL1 | 0.41373005 |
| 78 | MARK2 | 0.37611168 |
| 79 | EGFR | 0.37094057 |
| 80 | RPS6KA1 | 0.36593801 |
| 81 | CDK4 | 0.33940168 |
| 82 | PIM1 | 0.32795620 |
| 83 | PRKCD | 0.32599347 |
| 84 | MAPKAPK2 | 0.31290892 |
| 85 | RAF1 | 0.30196628 |
| 86 | MAPK4 | 0.30035221 |
| 87 | HIPK2 | 0.29656542 |
| 88 | PAK1 | 0.29341167 |
| 89 | SCYL2 | 0.28944473 |
| 90 | CAMK4 | 0.26617659 |
| 91 | CLK1 | 0.26156378 |
| 92 | RPS6KA5 | 0.25826007 |
| 93 | PRKD1 | 0.25811407 |
| 94 | CDC42BPA | 0.25771559 |
| 95 | MAP3K8 | 0.25238280 |
| 96 | MAPK11 | 0.24807576 |
| 97 | TTN | 0.24619032 |
| 98 | CCNB1 | 0.24222712 |
| 99 | ABL2 | 0.23680434 |
| 100 | SGK3 | 0.23675909 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Asthma_Homo sapiens_hsa05310 | 4.53021357 |
| 2 | Allograft rejection_Homo sapiens_hsa05330 | 3.76208416 |
| 3 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.69209124 |
| 4 | Leishmaniasis_Homo sapiens_hsa05140 | 3.59021080 |
| 5 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 3.57215617 |
| 6 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.52451087 |
| 7 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 3.06084802 |
| 8 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.98872839 |
| 9 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.52998090 |
| 10 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.46885395 |
| 11 | Viral myocarditis_Homo sapiens_hsa05416 | 2.43520794 |
| 12 | Tuberculosis_Homo sapiens_hsa05152 | 2.41589749 |
| 13 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.40097693 |
| 14 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 2.16308106 |
| 15 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.11060325 |
| 16 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.90810994 |
| 17 | Other glycan degradation_Homo sapiens_hsa00511 | 1.76709721 |
| 18 | Phagosome_Homo sapiens_hsa04145 | 1.73466151 |
| 19 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.72559324 |
| 20 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.70390114 |
| 21 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.65752524 |
| 22 | Influenza A_Homo sapiens_hsa05164 | 1.58710630 |
| 23 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.56263969 |
| 24 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.49735444 |
| 25 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.44093833 |
| 26 | Legionellosis_Homo sapiens_hsa05134 | 1.43727789 |
| 27 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.42851566 |
| 28 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.41897463 |
| 29 | Lysosome_Homo sapiens_hsa04142 | 1.35143728 |
| 30 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.34112723 |
| 31 | Pertussis_Homo sapiens_hsa05133 | 1.26939949 |
| 32 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.24327237 |
| 33 | Malaria_Homo sapiens_hsa05144 | 1.22607393 |
| 34 | Platelet activation_Homo sapiens_hsa04611 | 1.16418510 |
| 35 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.12678202 |
| 36 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.12140822 |
| 37 | Measles_Homo sapiens_hsa05162 | 1.07044926 |
| 38 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.99640972 |
| 39 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.98636109 |
| 40 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.97492548 |
| 41 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.93173540 |
| 42 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.92759495 |
| 43 | Shigellosis_Homo sapiens_hsa05131 | 0.92698251 |
| 44 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.92268660 |
| 45 | Salmonella infection_Homo sapiens_hsa05132 | 0.91177277 |
| 46 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.80245472 |
| 47 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.79945744 |
| 48 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.76020922 |
| 49 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.73107188 |
| 50 | Hepatitis B_Homo sapiens_hsa05161 | 0.72880247 |
| 51 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.71107393 |
| 52 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.69973457 |
| 53 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.69905724 |
| 54 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.58849475 |
| 55 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.57747797 |
| 56 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.57609930 |
| 57 | Apoptosis_Homo sapiens_hsa04210 | 0.54843200 |
| 58 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.52738352 |
| 59 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.52606712 |
| 60 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.51382757 |
| 61 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.51382219 |
| 62 | HTLV-I infection_Homo sapiens_hsa05166 | 0.51308071 |
| 63 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.44807172 |
| 64 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.42831686 |
| 65 | Hepatitis C_Homo sapiens_hsa05160 | 0.42001834 |
| 66 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.39653939 |
| 67 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.36915897 |
| 68 | Amoebiasis_Homo sapiens_hsa05146 | 0.36567334 |
| 69 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.36526408 |
| 70 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.33869702 |
| 71 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.33591356 |
| 72 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.31496532 |
| 73 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.30903899 |
| 74 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.30552190 |
| 75 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.29080784 |
| 76 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.26455316 |
| 77 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.25596840 |
| 78 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.25443319 |
| 79 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.24132899 |
| 80 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.23971157 |
| 81 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.21917101 |
| 82 | Endocytosis_Homo sapiens_hsa04144 | 0.21621165 |
| 83 | Olfactory transduction_Homo sapiens_hsa04740 | 0.21034936 |
| 84 | DNA replication_Homo sapiens_hsa03030 | 0.20230781 |
| 85 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.17747674 |
| 86 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.16885793 |
| 87 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.16264953 |
| 88 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.15278007 |
| 89 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.14713560 |
| 90 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.14388393 |
| 91 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.13529363 |
| 92 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.13444317 |
| 93 | Galactose metabolism_Homo sapiens_hsa00052 | 0.13369775 |
| 94 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.13255503 |
| 95 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.12851311 |
| 96 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.12686131 |
| 97 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.12097342 |
| 98 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.11064509 |
| 99 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.11037335 |
| 100 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.09963212 |

