

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | neutrophil activation involved in immune response (GO:0002283) | 5.71516640 |
| 2 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 5.65879306 |
| 3 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 5.65879306 |
| 4 | modulation by symbiont of host immune response (GO:0052553) | 5.65879306 |
| 5 | positive regulation by symbiont of host defense response (GO:0052509) | 5.65879306 |
| 6 | modulation by symbiont of host defense response (GO:0052031) | 5.65879306 |
| 7 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 5.65879306 |
| 8 | response to peptidoglycan (GO:0032494) | 5.55096651 |
| 9 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.44245720 |
| 10 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 5.37210479 |
| 11 | negative regulation of cell killing (GO:0031342) | 5.37210479 |
| 12 | negative regulation of interleukin-12 production (GO:0032695) | 5.34234593 |
| 13 | macrophage activation involved in immune response (GO:0002281) | 5.23904945 |
| 14 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.75775005 |
| 15 | detection of molecule of bacterial origin (GO:0032490) | 4.69767778 |
| 16 | detection of other organism (GO:0098543) | 4.64769586 |
| 17 | cellular extravasation (GO:0045123) | 4.55864957 |
| 18 | detection of bacterium (GO:0016045) | 4.30819731 |
| 19 | immunoglobulin mediated immune response (GO:0016064) | 4.29834202 |
| 20 | detection of external biotic stimulus (GO:0098581) | 4.28925092 |
| 21 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 4.27596411 |
| 22 | neutrophil activation (GO:0042119) | 4.12186886 |
| 23 | microglial cell activation (GO:0001774) | 4.04974605 |
| 24 | granulocyte activation (GO:0036230) | 4.03788870 |
| 25 | leukocyte aggregation (GO:0070486) | 3.99889953 |
| 26 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.97712920 |
| 27 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.97338750 |
| 28 | macrophage activation (GO:0042116) | 3.96380252 |
| 29 | regulation of mast cell degranulation (GO:0043304) | 3.94115639 |
| 30 | positive regulation of mast cell activation (GO:0033005) | 3.93691917 |
| 31 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.92966622 |
| 32 | respiratory burst (GO:0045730) | 3.92433408 |
| 33 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.87922304 |
| 34 | regulation of gamma-delta T cell activation (GO:0046643) | 3.84809945 |
| 35 | myeloid cell activation involved in immune response (GO:0002275) | 3.84450288 |
| 36 | detection of biotic stimulus (GO:0009595) | 3.81420965 |
| 37 | response to host immune response (GO:0052572) | 3.80315882 |
| 38 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.80315882 |
| 39 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 3.75484838 |
| 40 | regulation of mast cell activation involved in immune response (GO:0033006) | 3.64694925 |
| 41 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 3.57992282 |
| 42 | positive regulation of mast cell degranulation (GO:0043306) | 3.57210733 |
| 43 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 3.57210733 |
| 44 | leukocyte migration involved in inflammatory response (GO:0002523) | 3.56402079 |
| 45 | regulation of mast cell activation (GO:0033003) | 3.54690261 |
| 46 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.53891372 |
| 47 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.47611157 |
| 48 | regulation of leukocyte degranulation (GO:0043300) | 3.44731505 |
| 49 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.44562470 |
| 50 | response to host (GO:0075136) | 3.42101506 |
| 51 | response to host defenses (GO:0052200) | 3.42101506 |
| 52 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.42101506 |
| 53 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 3.38490257 |
| 54 | response to muramyl dipeptide (GO:0032495) | 3.37429477 |
| 55 | neutrophil mediated immunity (GO:0002446) | 3.27945307 |
| 56 | T-helper 1 type immune response (GO:0042088) | 3.27846955 |
| 57 | B cell mediated immunity (GO:0019724) | 3.27300489 |
| 58 | defense response to protozoan (GO:0042832) | 3.26835068 |
| 59 | positive regulation of myeloid leukocyte mediated immunity (GO:0002888) | 3.26084631 |
| 60 | germinal center formation (GO:0002467) | 3.25431994 |
| 61 | negative regulation of T cell mediated immunity (GO:0002710) | 3.24167168 |
| 62 | interferon-gamma-mediated signaling pathway (GO:0060333) | 3.23702415 |
| 63 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.22331322 |
| 64 | production of molecular mediator involved in inflammatory response (GO:0002532) | 3.21686208 |
| 65 | positive regulation of cellular amide metabolic process (GO:0034250) | 3.19760923 |
| 66 | regulation of T-helper 2 cell differentiation (GO:0045628) | 3.18721686 |
| 67 | negative regulation of cytokine production involved in immune response (GO:0002719) | 3.16586582 |
| 68 | regulation of T cell tolerance induction (GO:0002664) | 3.15590969 |
| 69 | neutrophil chemotaxis (GO:0030593) | 3.14224059 |
| 70 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 3.12906364 |
| 71 | regulation of tolerance induction (GO:0002643) | 3.09859843 |
| 72 | neutrophil migration (GO:1990266) | 3.06057481 |
| 73 | negative regulation of erythrocyte differentiation (GO:0045647) | 3.05705435 |
| 74 | cellular response to type I interferon (GO:0071357) | 3.04142273 |
| 75 | type I interferon signaling pathway (GO:0060337) | 3.04142273 |
| 76 | myeloid leukocyte activation (GO:0002274) | 3.02895847 |
| 77 | response to protozoan (GO:0001562) | 3.01963020 |
| 78 | response to type I interferon (GO:0034340) | 3.00663922 |
| 79 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 2.99862866 |
| 80 | positive regulation of antigen processing and presentation (GO:0002579) | 2.99425497 |
| 81 | regulation of antigen processing and presentation (GO:0002577) | 2.99325704 |
| 82 | positive regulation of leukocyte degranulation (GO:0043302) | 2.98458014 |
| 83 | regulation of gamma-delta T cell differentiation (GO:0045586) | 2.96533138 |
| 84 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 2.93572199 |
| 85 | leukocyte degranulation (GO:0043299) | 2.92789178 |
| 86 | regulation of regulated secretory pathway (GO:1903305) | 2.91552296 |
| 87 | regulation of interferon-alpha production (GO:0032647) | 2.91203339 |
| 88 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 2.90663620 |
| 89 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 2.90540817 |
| 90 | myeloid leukocyte mediated immunity (GO:0002444) | 2.90482863 |
| 91 | positive regulation of interferon-alpha production (GO:0032727) | 2.86789413 |
| 92 | positive regulation of toll-like receptor signaling pathway (GO:0034123) | 2.80439551 |
| 93 | negative regulation of interleukin-6 production (GO:0032715) | 2.80200374 |
| 94 | positive regulation of type 2 immune response (GO:0002830) | 2.79591690 |
| 95 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 2.77152557 |
| 96 | positive regulation of tumor necrosis factor superfamily cytokine production (GO:1903557) | 2.76918636 |
| 97 | granulocyte chemotaxis (GO:0071621) | 2.76364668 |
| 98 | myeloid dendritic cell differentiation (GO:0043011) | 2.74919950 |
| 99 | myeloid dendritic cell activation (GO:0001773) | 2.73423973 |
| 100 | positive regulation of B cell differentiation (GO:0045579) | 2.72669324 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 5.47034352 |
| 2 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 5.12151563 |
| 3 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 4.91707448 |
| 4 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 3.78851256 |
| 5 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.69077584 |
| 6 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.64579362 |
| 7 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.43332380 |
| 8 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.22527497 |
| 9 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 3.06461479 |
| 10 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 3.00247035 |
| 11 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.73755950 |
| 12 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.72560423 |
| 13 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.71447450 |
| 14 | * SPI1_23127762_ChIP-Seq_K562_Human | 2.67010627 |
| 15 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.65372938 |
| 16 | VDR_24763502_ChIP-Seq_THP-1_Human | 2.65267644 |
| 17 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 2.64809001 |
| 18 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.60777336 |
| 19 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.51157673 |
| 20 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.44515430 |
| 21 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.44230342 |
| 22 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 2.34707451 |
| 23 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.29688977 |
| 24 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.29098223 |
| 25 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 2.27128094 |
| 26 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.20547330 |
| 27 | VDR_24787735_ChIP-Seq_THP-1_Human | 2.17546139 |
| 28 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 2.10115537 |
| 29 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 2.09935686 |
| 30 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.00103128 |
| 31 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 2.00038507 |
| 32 | MAF_26560356_Chip-Seq_TH1_Human | 1.97336023 |
| 33 | MYB_26560356_Chip-Seq_TH2_Human | 1.92578211 |
| 34 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.90254370 |
| 35 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.84384046 |
| 36 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.77539319 |
| 37 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.73655129 |
| 38 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.71983033 |
| 39 | * UTX_26944678_Chip-Seq_JUKART_Human | 1.69115371 |
| 40 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.67296244 |
| 41 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.67230358 |
| 42 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.65341980 |
| 43 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.59104464 |
| 44 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.58347758 |
| 45 | MYB_26560356_Chip-Seq_TH1_Human | 1.57385933 |
| 46 | MYC_22102868_ChIP-Seq_BL_Human | 1.55333818 |
| 47 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.54670465 |
| 48 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.52305071 |
| 49 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.48174648 |
| 50 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.46019631 |
| 51 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.44249353 |
| 52 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.42118506 |
| 53 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.41850019 |
| 54 | MAF_26560356_Chip-Seq_TH2_Human | 1.40774273 |
| 55 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.40354220 |
| 56 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.40164626 |
| 57 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.39390226 |
| 58 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.39220942 |
| 59 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.38309428 |
| 60 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.37917866 |
| 61 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.36140714 |
| 62 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.33166908 |
| 63 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.32607734 |
| 64 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.31557711 |
| 65 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.31407157 |
| 66 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.31295544 |
| 67 | GATA1_22025678_ChIP-Seq_K562_Human | 1.30312313 |
| 68 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.29731639 |
| 69 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.25411871 |
| 70 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.24785981 |
| 71 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.23966503 |
| 72 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.22797422 |
| 73 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 1.19700533 |
| 74 | GATA3_26560356_Chip-Seq_TH2_Human | 1.19478353 |
| 75 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.17408349 |
| 76 | GATA1_19941826_ChIP-Seq_K562_Human | 1.16394299 |
| 77 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.15838136 |
| 78 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.14774135 |
| 79 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.12547176 |
| 80 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.08506343 |
| 81 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.06586392 |
| 82 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.03720515 |
| 83 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.01852665 |
| 84 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.01318965 |
| 85 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.01191015 |
| 86 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.99967137 |
| 87 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.98923986 |
| 88 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 0.98179991 |
| 89 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.93104357 |
| 90 | GATA2_19941826_ChIP-Seq_K562_Human | 0.89620336 |
| 91 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 0.88074979 |
| 92 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.84810430 |
| 93 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.82076574 |
| 94 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.81094005 |
| 95 | RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.80475196 |
| 96 | * NCOR1_26117541_ChIP-Seq_K562_Human | 0.76679138 |
| 97 | GATA1_19941827_ChIP-Seq_MEL86_Mouse | 0.76627134 |
| 98 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 0.76454002 |
| 99 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 0.70484338 |
| 100 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.67668813 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003724_increased_susceptibility_to | 4.43755046 |
| 2 | MP0003303_peritoneal_inflammation | 4.11924538 |
| 3 | MP0003436_decreased_susceptibility_to | 4.01109274 |
| 4 | MP0001835_abnormal_antigen_presentation | 3.53639391 |
| 5 | MP0006082_CNS_inflammation | 3.29149803 |
| 6 | MP0002419_abnormal_innate_immunity | 3.24430961 |
| 7 | MP0009785_altered_susceptibility_to | 3.10396371 |
| 8 | MP0005671_abnormal_response_to | 2.94011500 |
| 9 | MP0002148_abnormal_hypersensitivity_rea | 2.93789984 |
| 10 | MP0005025_abnormal_response_to | 2.84263544 |
| 11 | MP0005000_abnormal_immune_tolerance | 2.81919063 |
| 12 | MP0001790_abnormal_immune_system | 2.74555869 |
| 13 | MP0005387_immune_system_phenotype | 2.74555869 |
| 14 | MP0005058_abnormal_lysosome_morphology | 2.67914161 |
| 15 | MP0001800_abnormal_humoral_immune | 2.54043545 |
| 16 | MP0000685_abnormal_immune_system | 2.49840252 |
| 17 | MP0003172_abnormal_lysosome_physiology | 2.48565630 |
| 18 | MP0003191_abnormal_cellular_cholesterol | 2.46241015 |
| 19 | MP0003300_gastrointestinal_ulcer | 2.44648312 |
| 20 | MP0002452_abnormal_antigen_presenting | 2.44530684 |
| 21 | MP0002723_abnormal_immune_serum | 2.44510827 |
| 22 | MP0002420_abnormal_adaptive_immunity | 2.25750582 |
| 23 | MP0001819_abnormal_immune_cell | 2.24096592 |
| 24 | MP0001533_abnormal_skeleton_physiology | 2.22894922 |
| 25 | MP0005464_abnormal_platelet_physiology | 2.01454044 |
| 26 | MP0009278_abnormal_bone_marrow | 2.00654601 |
| 27 | MP0009764_decreased_sensitivity_to | 1.93358581 |
| 28 | MP0002405_respiratory_system_inflammati | 1.91596763 |
| 29 | MP0004510_myositis | 1.88927285 |
| 30 | MP0003075_altered_response_to | 1.87123509 |
| 31 | MP0001845_abnormal_inflammatory_respons | 1.84515083 |
| 32 | MP0008260_abnormal_autophagy | 1.78260907 |
| 33 | MP0000343_altered_response_to | 1.76869693 |
| 34 | MP0009840_abnormal_foam_cell | 1.71540800 |
| 35 | MP0004947_skin_inflammation | 1.69303315 |
| 36 | MP0003828_pulmonary_edema | 1.67434589 |
| 37 | MP0010155_abnormal_intestine_physiology | 1.64498902 |
| 38 | MP0000716_abnormal_immune_system | 1.61885914 |
| 39 | MP0008469_abnormal_protein_level | 1.60836106 |
| 40 | MP0002998_abnormal_bone_remodeling | 1.59209653 |
| 41 | MP0000604_amyloidosis | 1.58591148 |
| 42 | MP0003690_abnormal_glial_cell | 1.56524399 |
| 43 | MP0005451_abnormal_body_composition | 1.56135104 |
| 44 | MP0005397_hematopoietic_system_phenotyp | 1.52684279 |
| 45 | MP0001545_abnormal_hematopoietic_system | 1.52684279 |
| 46 | MP0005310_abnormal_salivary_gland | 1.51933718 |
| 47 | MP0002398_abnormal_bone_marrow | 1.49235865 |
| 48 | MP0000858_altered_metastatic_potential | 1.45802906 |
| 49 | MP0009333_abnormal_splenocyte_physiolog | 1.43838044 |
| 50 | MP0001853_heart_inflammation | 1.33737491 |
| 51 | MP0003806_abnormal_nucleotide_metabolis | 1.30393821 |
| 52 | MP0000689_abnormal_spleen_morphology | 1.30135041 |
| 53 | MP0004883_abnormal_blood_vessel | 1.29391711 |
| 54 | MP0003763_abnormal_thymus_physiology | 1.29316108 |
| 55 | MP0002277_abnormal_respiratory_mucosa | 1.27907928 |
| 56 | MP0000465_gastrointestinal_hemorrhage | 1.27107869 |
| 57 | MP0005166_decreased_susceptibility_to | 1.25460892 |
| 58 | MP0002429_abnormal_blood_cell | 1.25263705 |
| 59 | MP0008004_abnormal_stomach_pH | 1.23669532 |
| 60 | MP0002722_abnormal_immune_system | 1.22800461 |
| 61 | MP0003183_abnormal_peptide_metabolism | 1.22009781 |
| 62 | MP0003448_altered_tumor_morphology | 1.21767569 |
| 63 | MP0002132_abnormal_respiratory_system | 1.18978748 |
| 64 | MP0005167_abnormal_blood-brain_barrier | 1.16934778 |
| 65 | MP0005164_abnormal_response_to | 1.15926327 |
| 66 | MP0001851_eye_inflammation | 1.08954168 |
| 67 | MP0003656_abnormal_erythrocyte_physiolo | 1.03906952 |
| 68 | MP0003866_abnormal_defecation | 1.01634400 |
| 69 | MP0009763_increased_sensitivity_to | 0.92885205 |
| 70 | MP0005390_skeleton_phenotype | 0.88689269 |
| 71 | MP0006054_spinal_hemorrhage | 0.87129156 |
| 72 | MP0000703_abnormal_thymus_morphology | 0.86678292 |
| 73 | MP0000920_abnormal_myelination | 0.86384246 |
| 74 | MP0001663_abnormal_digestive_system | 0.83514820 |
| 75 | MP0004381_abnormal_hair_follicle | 0.79777222 |
| 76 | MP0003329_amyloid_beta_deposits | 0.77981187 |
| 77 | MP0003453_abnormal_keratinocyte_physiol | 0.77231526 |
| 78 | MP0003795_abnormal_bone_structure | 0.76512509 |
| 79 | MP0002254_reproductive_system_inflammat | 0.76027440 |
| 80 | MP0002139_abnormal_hepatobiliary_system | 0.75874845 |
| 81 | MP0009765_abnormal_xenobiotic_induced | 0.72919149 |
| 82 | MP0002332_abnormal_exercise_endurance | 0.71800417 |
| 83 | MP0000249_abnormal_blood_vessel | 0.68227730 |
| 84 | MP0008874_decreased_physiological_sensi | 0.68110243 |
| 85 | MP0002138_abnormal_hepatobiliary_system | 0.66021150 |
| 86 | MP0002933_joint_inflammation | 0.65985859 |
| 87 | MP0000015_abnormal_ear_pigmentation | 0.61993190 |
| 88 | MP0003091_abnormal_cell_migration | 0.61131932 |
| 89 | MP0002396_abnormal_hematopoietic_system | 0.60197934 |
| 90 | MP0004808_abnormal_hematopoietic_stem | 0.59954373 |
| 91 | MP0000569_abnormal_digit_pigmentation | 0.59244875 |
| 92 | MP0001873_stomach_inflammation | 0.57626484 |
| 93 | MP0000371_diluted_coat_color | 0.57502740 |
| 94 | MP0005319_abnormal_enzyme/_coenzyme | 0.56259647 |
| 95 | MP0000490_abnormal_crypts_of | 0.54764828 |
| 96 | MP0000609_abnormal_liver_physiology | 0.49052130 |
| 97 | MP0003195_calcinosis | 0.47207469 |
| 98 | MP0003045_fibrosis | 0.46794032 |
| 99 | MP0003221_abnormal_cardiomyocyte_apopto | 0.46658673 |
| 100 | MP0001542_abnormal_bone_strength | 0.45295828 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Eczematoid dermatitis (HP:0000976) | 6.22020852 |
| 2 | Recurrent abscess formation (HP:0002722) | 6.17176911 |
| 3 | Recurrent bacterial skin infections (HP:0005406) | 6.01831380 |
| 4 | Abnormality of macrophages (HP:0004311) | 5.88700441 |
| 5 | Recurrent gram-negative bacterial infections (HP:0005420) | 5.29938098 |
| 6 | Myositis (HP:0100614) | 5.16821454 |
| 7 | Orchitis (HP:0100796) | 5.02302295 |
| 8 | Abnormality of liposaccharide metabolism (HP:0010968) | 4.97446273 |
| 9 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 4.97446273 |
| 10 | Abnormality of glycolipid metabolism (HP:0010969) | 4.97446273 |
| 11 | Optic neuritis (HP:0100653) | 4.77431491 |
| 12 | Retrobulbar optic neuritis (HP:0100654) | 4.77431491 |
| 13 | Stomatitis (HP:0010280) | 4.67504127 |
| 14 | Mediastinal lymphadenopathy (HP:0100721) | 4.15850129 |
| 15 | Increased cerebral lipofuscin (HP:0011813) | 4.05068302 |
| 16 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.90043729 |
| 17 | Chronic obstructive pulmonary disease (HP:0006510) | 3.82025189 |
| 18 | Obstructive lung disease (HP:0006536) | 3.82025189 |
| 19 | Recurrent skin infections (HP:0001581) | 3.74874675 |
| 20 | Recurrent fungal infections (HP:0002841) | 3.65874458 |
| 21 | Systemic lupus erythematosus (HP:0002725) | 3.59540311 |
| 22 | Gingivitis (HP:0000230) | 3.48146935 |
| 23 | Spontaneous hematomas (HP:0007420) | 3.44138200 |
| 24 | Disinhibition (HP:0000734) | 3.43230716 |
| 25 | Keratoconjunctivitis sicca (HP:0001097) | 3.41945377 |
| 26 | Vacuolated lymphocytes (HP:0001922) | 3.39833537 |
| 27 | Loss of speech (HP:0002371) | 3.31720190 |
| 28 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 3.31615647 |
| 29 | Meningitis (HP:0001287) | 3.31065085 |
| 30 | Gastrointestinal infarctions (HP:0005244) | 3.27094285 |
| 31 | Keratoconjunctivitis (HP:0001096) | 3.13935253 |
| 32 | Dysostosis multiplex (HP:0000943) | 3.12801000 |
| 33 | Amyloidosis (HP:0011034) | 3.12375496 |
| 34 | Urticaria (HP:0001025) | 3.10185549 |
| 35 | Recurrent cutaneous fungal infections (HP:0011370) | 3.06877132 |
| 36 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.06877132 |
| 37 | Encephalitis (HP:0002383) | 3.04721328 |
| 38 | Vasculitis (HP:0002633) | 3.04296618 |
| 39 | Hemoptysis (HP:0002105) | 2.94171028 |
| 40 | Pulmonary infiltrates (HP:0002113) | 2.91241670 |
| 41 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.84636485 |
| 42 | Petechiae (HP:0000967) | 2.76776574 |
| 43 | Mutism (HP:0002300) | 2.73922791 |
| 44 | Increased IgE level (HP:0003212) | 2.71806693 |
| 45 | T lymphocytopenia (HP:0005403) | 2.70912093 |
| 46 | Autoimmune thrombocytopenia (HP:0001973) | 2.70054649 |
| 47 | Purpura (HP:0000979) | 2.69505600 |
| 48 | Leukocytosis (HP:0001974) | 2.65241884 |
| 49 | Episodic fever (HP:0001954) | 2.64393806 |
| 50 | Prolonged bleeding time (HP:0003010) | 2.63842911 |
| 51 | Cellulitis (HP:0100658) | 2.60407498 |
| 52 | Increased serum ferritin (HP:0003281) | 2.58037443 |
| 53 | Abnormality of T cell number (HP:0011839) | 2.57985665 |
| 54 | Chest pain (HP:0100749) | 2.54300461 |
| 55 | Gingival bleeding (HP:0000225) | 2.52727875 |
| 56 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 2.50537260 |
| 57 | Arterial thrombosis (HP:0004420) | 2.48761315 |
| 58 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.46527877 |
| 59 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.46527877 |
| 60 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.46527877 |
| 61 | Recurrent viral infections (HP:0004429) | 2.45833819 |
| 62 | Epistaxis (HP:0000421) | 2.45308341 |
| 63 | Pulmonary embolism (HP:0002204) | 2.44742387 |
| 64 | Anorexia (HP:0002039) | 2.43126016 |
| 65 | Increased IgM level (HP:0003496) | 2.42885928 |
| 66 | Hepatosplenomegaly (HP:0001433) | 2.34253835 |
| 67 | Abnormality of iron homeostasis (HP:0011031) | 2.30229873 |
| 68 | Pustule (HP:0200039) | 2.28907648 |
| 69 | Gangrene (HP:0100758) | 2.27769018 |
| 70 | Mucopolysacchariduria (HP:0008155) | 2.26423020 |
| 71 | Urinary glycosaminoglycan excretion (HP:0003541) | 2.26423020 |
| 72 | Glomerulonephritis (HP:0000099) | 2.24308201 |
| 73 | Hematochezia (HP:0002573) | 2.24061426 |
| 74 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 2.18708420 |
| 75 | Inflammation of the large intestine (HP:0002037) | 2.18274341 |
| 76 | Agnosia (HP:0010524) | 2.14929906 |
| 77 | Peritonitis (HP:0002586) | 2.14879432 |
| 78 | Osteomyelitis (HP:0002754) | 2.14669629 |
| 79 | Upper motor neuron abnormality (HP:0002127) | 2.13115015 |
| 80 | Polyneuropathy (HP:0001271) | 2.12729135 |
| 81 | Axonal loss (HP:0003447) | 2.10922089 |
| 82 | Abnormality of the pleura (HP:0002103) | 2.07736596 |
| 83 | Gastrointestinal inflammation (HP:0004386) | 2.06051724 |
| 84 | Neuronal loss in central nervous system (HP:0002529) | 2.05553471 |
| 85 | Vertigo (HP:0002321) | 2.04455298 |
| 86 | Myocardial infarction (HP:0001658) | 2.02412018 |
| 87 | Premature loss of primary teeth (HP:0006323) | 2.01029378 |
| 88 | Hypergammaglobulinemia (HP:0010702) | 2.00428725 |
| 89 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 1.98490382 |
| 90 | Hypochromic anemia (HP:0001931) | 1.97981796 |
| 91 | Hypochromic microcytic anemia (HP:0004840) | 1.97143355 |
| 92 | Abnormality of the endocardium (HP:0004306) | 1.96867860 |
| 93 | Abnormality of T cells (HP:0002843) | 1.96650727 |
| 94 | Progressive neurologic deterioration (HP:0002344) | 1.94636578 |
| 95 | Glomerulopathy (HP:0100820) | 1.94447936 |
| 96 | Granulocytopenia (HP:0001913) | 1.92016664 |
| 97 | Sepsis (HP:0100806) | 1.91486959 |
| 98 | Inappropriate behavior (HP:0000719) | 1.89548158 |
| 99 | Neurofibrillary tangles (HP:0002185) | 1.88702907 |
| 100 | Acne (HP:0001061) | 1.88452405 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RIPK4 | 4.66346747 |
| 2 | BLK | 3.74510950 |
| 3 | IRAK4 | 3.01184280 |
| 4 | MAP4K1 | 3.00975313 |
| 5 | CSK | 2.93504404 |
| 6 | TYK2 | 2.86297788 |
| 7 | MAP2K3 | 2.86243039 |
| 8 | ERN1 | 2.53101233 |
| 9 | FGR | 2.35265161 |
| 10 | FES | 2.30067336 |
| 11 | MAP3K14 | 2.25462235 |
| 12 | ZAP70 | 2.00383960 |
| 13 | TAOK1 | 1.97818971 |
| 14 | IRAK3 | 1.97264989 |
| 15 | PRPF4B | 1.97183412 |
| 16 | MAP3K3 | 1.95908068 |
| 17 | MAP3K11 | 1.90353980 |
| 18 | JAK3 | 1.81198763 |
| 19 | TNK2 | 1.77846265 |
| 20 | TXK | 1.74371391 |
| 21 | MATK | 1.73953509 |
| 22 | TGFBR2 | 1.69957718 |
| 23 | TBK1 | 1.69052828 |
| 24 | SYK | 1.63605031 |
| 25 | GRK7 | 1.57405715 |
| 26 | HCK | 1.53524721 |
| 27 | IKBKE | 1.53243157 |
| 28 | BTK | 1.51357961 |
| 29 | EPHB1 | 1.50524163 |
| 30 | GRK6 | 1.49622416 |
| 31 | CSF1R | 1.48911004 |
| 32 | LYN | 1.43973989 |
| 33 | MAP3K13 | 1.41908493 |
| 34 | TAOK2 | 1.40726780 |
| 35 | JAK2 | 1.37493121 |
| 36 | MAP3K1 | 1.34477372 |
| 37 | JAK1 | 1.30321344 |
| 38 | IKBKB | 1.27002412 |
| 39 | TAOK3 | 1.17544504 |
| 40 | SIK3 | 1.16908155 |
| 41 | LCK | 1.12153974 |
| 42 | BMPR2 | 1.11821098 |
| 43 | MARK3 | 1.09824771 |
| 44 | KSR2 | 1.06479799 |
| 45 | KIT | 1.04373517 |
| 46 | IRAK1 | 0.99798258 |
| 47 | IRAK2 | 0.97148540 |
| 48 | YES1 | 0.95804099 |
| 49 | CDC42BPA | 0.91183614 |
| 50 | NME2 | 0.85380414 |
| 51 | CAMKK2 | 0.85334727 |
| 52 | PDK1 | 0.84478480 |
| 53 | STK10 | 0.83908852 |
| 54 | ITK | 0.83904057 |
| 55 | MARK2 | 0.81322768 |
| 56 | MAP3K5 | 0.80539188 |
| 57 | PDPK1 | 0.79196037 |
| 58 | MOS | 0.79171144 |
| 59 | TESK2 | 0.73757157 |
| 60 | MAP3K6 | 0.73513042 |
| 61 | TEC | 0.72290221 |
| 62 | ACVR1B | 0.65489664 |
| 63 | PRKD2 | 0.60282476 |
| 64 | DAPK2 | 0.59025483 |
| 65 | FYN | 0.58877946 |
| 66 | MAP3K2 | 0.58452529 |
| 67 | DDR2 | 0.57413271 |
| 68 | MAP2K6 | 0.55723108 |
| 69 | SIK2 | 0.55645937 |
| 70 | MAPK12 | 0.53975656 |
| 71 | RPS6KC1 | 0.52486046 |
| 72 | RPS6KL1 | 0.52486046 |
| 73 | PTK6 | 0.52386525 |
| 74 | PIK3CG | 0.51604582 |
| 75 | KSR1 | 0.51152549 |
| 76 | EPHA3 | 0.51026518 |
| 77 | MAPK7 | 0.50671380 |
| 78 | CAMK1D | 0.49906312 |
| 79 | MAP2K4 | 0.48753301 |
| 80 | PIM1 | 0.45329326 |
| 81 | SGK3 | 0.45102503 |
| 82 | RPS6KA6 | 0.43709417 |
| 83 | CHUK | 0.40366892 |
| 84 | DYRK1B | 0.39249135 |
| 85 | PRKCQ | 0.38968188 |
| 86 | LRRK2 | 0.36690831 |
| 87 | RIPK1 | 0.36068299 |
| 88 | HIPK2 | 0.34122693 |
| 89 | ABL1 | 0.33333482 |
| 90 | STK11 | 0.33292191 |
| 91 | MAPKAPK2 | 0.32412588 |
| 92 | CDK19 | 0.31059783 |
| 93 | PRKCD | 0.30955690 |
| 94 | FGFR3 | 0.30772553 |
| 95 | CAMKK1 | 0.30542260 |
| 96 | ADRBK2 | 0.30285209 |
| 97 | RAF1 | 0.29908297 |
| 98 | TRIB3 | 0.29768856 |
| 99 | PTK2B | 0.29252175 |
| 100 | CDK6 | 0.29068234 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 3.36609769 |
| 2 | Osteoclast differentiation_Homo sapiens_hsa04380 | 3.15049999 |
| 3 | Leishmaniasis_Homo sapiens_hsa05140 | 3.13763833 |
| 4 | Tuberculosis_Homo sapiens_hsa05152 | 2.41486203 |
| 5 | Allograft rejection_Homo sapiens_hsa05330 | 2.39104568 |
| 6 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.35633219 |
| 7 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.34942382 |
| 8 | Other glycan degradation_Homo sapiens_hsa00511 | 2.31816210 |
| 9 | Malaria_Homo sapiens_hsa05144 | 2.15489795 |
| 10 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.10375753 |
| 11 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 2.08825851 |
| 12 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 2.08772920 |
| 13 | Lysosome_Homo sapiens_hsa04142 | 1.99375088 |
| 14 | Legionellosis_Homo sapiens_hsa05134 | 1.97399326 |
| 15 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.96545427 |
| 16 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.94180087 |
| 17 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.87091445 |
| 18 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.81835378 |
| 19 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.80700900 |
| 20 | Asthma_Homo sapiens_hsa05310 | 1.79014649 |
| 21 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.77750794 |
| 22 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.74923221 |
| 23 | Phagosome_Homo sapiens_hsa04145 | 1.74247996 |
| 24 | Pertussis_Homo sapiens_hsa05133 | 1.67841218 |
| 25 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.67169682 |
| 26 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.67087442 |
| 27 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.56922766 |
| 28 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.56887697 |
| 29 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.54444420 |
| 30 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.52546838 |
| 31 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.51557670 |
| 32 | Influenza A_Homo sapiens_hsa05164 | 1.46627449 |
| 33 | Measles_Homo sapiens_hsa05162 | 1.45045058 |
| 34 | Viral myocarditis_Homo sapiens_hsa05416 | 1.44983094 |
| 35 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.38436142 |
| 36 | Salmonella infection_Homo sapiens_hsa05132 | 1.37084702 |
| 37 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.36129060 |
| 38 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.34347912 |
| 39 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.34156609 |
| 40 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.31285881 |
| 41 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.29808511 |
| 42 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.21242835 |
| 43 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.19700075 |
| 44 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.17700544 |
| 45 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.13689819 |
| 46 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.07417345 |
| 47 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.05167696 |
| 48 | Shigellosis_Homo sapiens_hsa05131 | 1.00729937 |
| 49 | Hepatitis B_Homo sapiens_hsa05161 | 0.99194111 |
| 50 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.96702888 |
| 51 | Hepatitis C_Homo sapiens_hsa05160 | 0.94462563 |
| 52 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.93885818 |
| 53 | Platelet activation_Homo sapiens_hsa04611 | 0.91843806 |
| 54 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.90661157 |
| 55 | Apoptosis_Homo sapiens_hsa04210 | 0.86482099 |
| 56 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.80160512 |
| 57 | Amoebiasis_Homo sapiens_hsa05146 | 0.79430319 |
| 58 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.74207585 |
| 59 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.72907780 |
| 60 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.72017765 |
| 61 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.71877886 |
| 62 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.68473922 |
| 63 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.68205784 |
| 64 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.66959871 |
| 65 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.65568500 |
| 66 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.65389675 |
| 67 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.64702751 |
| 68 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.63982674 |
| 69 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.63600171 |
| 70 | Endocytosis_Homo sapiens_hsa04144 | 0.60852538 |
| 71 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.59060444 |
| 72 | Prion diseases_Homo sapiens_hsa05020 | 0.58139673 |
| 73 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.57640209 |
| 74 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.57387288 |
| 75 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.51028946 |
| 76 | Bladder cancer_Homo sapiens_hsa05219 | 0.49697741 |
| 77 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.48623880 |
| 78 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.47955728 |
| 79 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.47848742 |
| 80 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.47271880 |
| 81 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.44483219 |
| 82 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.44481454 |
| 83 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.44083019 |
| 84 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.41757129 |
| 85 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.40894986 |
| 86 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.38214030 |
| 87 | HTLV-I infection_Homo sapiens_hsa05166 | 0.37142199 |
| 88 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.35702090 |
| 89 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.32884833 |
| 90 | Insulin resistance_Homo sapiens_hsa04931 | 0.32440700 |
| 91 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.31989659 |
| 92 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.31592789 |
| 93 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.30619289 |
| 94 | Galactose metabolism_Homo sapiens_hsa00052 | 0.29666012 |
| 95 | Endometrial cancer_Homo sapiens_hsa05213 | 0.29132589 |
| 96 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.27945380 |
| 97 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.27594877 |
| 98 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.27581243 |
| 99 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.27449265 |
| 100 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.27285623 |

