

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | modulation by symbiont of host defense response (GO:0052031) | 6.52148522 |
| 2 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 6.52148522 |
| 3 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 6.52148522 |
| 4 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 6.52148522 |
| 5 | modulation by symbiont of host immune response (GO:0052553) | 6.52148522 |
| 6 | positive regulation by symbiont of host defense response (GO:0052509) | 6.52148522 |
| 7 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 6.48793179 |
| 8 | detection of molecule of bacterial origin (GO:0032490) | 5.77769648 |
| 9 | macrophage activation involved in immune response (GO:0002281) | 5.64357040 |
| 10 | neutrophil activation involved in immune response (GO:0002283) | 5.44825026 |
| 11 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.41001292 |
| 12 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 5.39622772 |
| 13 | cellular extravasation (GO:0045123) | 5.20605791 |
| 14 | response to peptidoglycan (GO:0032494) | 5.20010572 |
| 15 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 5.05096667 |
| 16 | negative regulation of cell killing (GO:0031342) | 5.05096667 |
| 17 | detection of other organism (GO:0098543) | 4.95363312 |
| 18 | regulation of interferon-beta biosynthetic process (GO:0045357) | 4.92186265 |
| 19 | microglial cell activation (GO:0001774) | 4.85208938 |
| 20 | detection of external biotic stimulus (GO:0098581) | 4.78964784 |
| 21 | negative regulation of interleukin-12 production (GO:0032695) | 4.63660411 |
| 22 | regulation of B cell receptor signaling pathway (GO:0050855) | 4.52398212 |
| 23 | macrophage activation (GO:0042116) | 4.46067844 |
| 24 | neutrophil activation (GO:0042119) | 4.35236791 |
| 25 | detection of bacterium (GO:0016045) | 4.32907153 |
| 26 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 4.31902319 |
| 27 | response to host immune response (GO:0052572) | 4.31902319 |
| 28 | detection of biotic stimulus (GO:0009595) | 4.27515661 |
| 29 | neutrophil mediated immunity (GO:0002446) | 4.23169322 |
| 30 | regulation of gamma-delta T cell activation (GO:0046643) | 4.13393130 |
| 31 | myeloid cell activation involved in immune response (GO:0002275) | 4.12438651 |
| 32 | respiratory burst (GO:0045730) | 4.04566315 |
| 33 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 4.00389095 |
| 34 | positive regulation of mast cell activation (GO:0033005) | 3.97496382 |
| 35 | granulocyte activation (GO:0036230) | 3.95413654 |
| 36 | leukocyte migration involved in inflammatory response (GO:0002523) | 3.93744302 |
| 37 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.91845292 |
| 38 | response to host (GO:0075136) | 3.91845292 |
| 39 | response to host defenses (GO:0052200) | 3.91845292 |
| 40 | regulation of mast cell degranulation (GO:0043304) | 3.91844254 |
| 41 | regulation of T-helper 2 cell differentiation (GO:0045628) | 3.91027379 |
| 42 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.83340606 |
| 43 | leukocyte aggregation (GO:0070486) | 3.79963157 |
| 44 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.75093614 |
| 45 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.72823117 |
| 46 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 3.72164244 |
| 47 | production of molecular mediator involved in inflammatory response (GO:0002532) | 3.68641235 |
| 48 | regulation of mast cell activation involved in immune response (GO:0033006) | 3.65666536 |
| 49 | immunoglobulin mediated immune response (GO:0016064) | 3.64880505 |
| 50 | myeloid leukocyte mediated immunity (GO:0002444) | 3.58828823 |
| 51 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.57219370 |
| 52 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 3.55403879 |
| 53 | positive regulation of mast cell degranulation (GO:0043306) | 3.55403879 |
| 54 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.53851303 |
| 55 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 3.53038904 |
| 56 | regulation of mast cell activation (GO:0033003) | 3.51319104 |
| 57 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 3.48002774 |
| 58 | cell wall macromolecule catabolic process (GO:0016998) | 3.40325545 |
| 59 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 3.36742363 |
| 60 | leukocyte degranulation (GO:0043299) | 3.35700249 |
| 61 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 3.34966640 |
| 62 | regulation of leukocyte degranulation (GO:0043300) | 3.32576954 |
| 63 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.32009897 |
| 64 | fusion of sperm to egg plasma membrane (GO:0007342) | 3.25715723 |
| 65 | negative regulation of T cell mediated immunity (GO:0002710) | 3.25303891 |
| 66 | negative regulation of leukocyte mediated immunity (GO:0002704) | 3.24644053 |
| 67 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 3.18870628 |
| 68 | response to muramyl dipeptide (GO:0032495) | 3.17952113 |
| 69 | positive regulation of myeloid leukocyte mediated immunity (GO:0002888) | 3.13261543 |
| 70 | myeloid leukocyte activation (GO:0002274) | 3.13021434 |
| 71 | positive regulation of cellular amide metabolic process (GO:0034250) | 3.07818877 |
| 72 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 3.07042166 |
| 73 | defense response to protozoan (GO:0042832) | 3.05128948 |
| 74 | germinal center formation (GO:0002467) | 3.04140928 |
| 75 | positive regulation of interferon-alpha production (GO:0032727) | 3.03875819 |
| 76 | response to interleukin-15 (GO:0070672) | 3.03201048 |
| 77 | regulation of interleukin-8 biosynthetic process (GO:0045414) | 3.02543539 |
| 78 | neutrophil chemotaxis (GO:0030593) | 3.01274270 |
| 79 | B cell receptor signaling pathway (GO:0050853) | 2.99877197 |
| 80 | positive regulation of type 2 immune response (GO:0002830) | 2.99372440 |
| 81 | acrosome reaction (GO:0007340) | 2.98258178 |
| 82 | positive regulation of toll-like receptor signaling pathway (GO:0034123) | 2.97283899 |
| 83 | cell wall macromolecule metabolic process (GO:0044036) | 2.96102253 |
| 84 | T-helper 1 type immune response (GO:0042088) | 2.96099185 |
| 85 | negative regulation of interleukin-6 production (GO:0032715) | 2.96089854 |
| 86 | neutrophil migration (GO:1990266) | 2.93463571 |
| 87 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.92728304 |
| 88 | regulation of tolerance induction (GO:0002643) | 2.91968129 |
| 89 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 2.91953130 |
| 90 | regulation of regulated secretory pathway (GO:1903305) | 2.90353732 |
| 91 | interferon-gamma-mediated signaling pathway (GO:0060333) | 2.88938653 |
| 92 | regulation of interferon-alpha production (GO:0032647) | 2.88545145 |
| 93 | mast cell activation (GO:0045576) | 2.83868917 |
| 94 | cellular response to type I interferon (GO:0071357) | 2.82953490 |
| 95 | type I interferon signaling pathway (GO:0060337) | 2.82953490 |
| 96 | I-kappaB phosphorylation (GO:0007252) | 2.82883511 |
| 97 | B cell mediated immunity (GO:0019724) | 2.81771422 |
| 98 | regulation of macrophage cytokine production (GO:0010935) | 2.81063608 |
| 99 | sperm motility (GO:0030317) | 2.79874788 |
| 100 | response to type I interferon (GO:0034340) | 2.79763161 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 4.87889750 |
| 2 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 4.87041022 |
| 3 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 4.26712671 |
| 4 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.45294853 |
| 5 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.41349269 |
| 6 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 3.24176695 |
| 7 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.08621499 |
| 8 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.85893822 |
| 9 | SPI1_23127762_ChIP-Seq_K562_Human | 2.74349292 |
| 10 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.67132236 |
| 11 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.64870064 |
| 12 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.63874166 |
| 13 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.50021087 |
| 14 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.48039442 |
| 15 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.47264271 |
| 16 | VDR_24763502_ChIP-Seq_THP-1_Human | 2.43182766 |
| 17 | VDR_24787735_ChIP-Seq_THP-1_Human | 2.36212584 |
| 18 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.18892463 |
| 19 | MYB_26560356_Chip-Seq_TH2_Human | 2.18764175 |
| 20 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.18101419 |
| 21 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.17431664 |
| 22 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.16347411 |
| 23 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 2.10992707 |
| 24 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 2.01792335 |
| 25 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.99756325 |
| 26 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.94773274 |
| 27 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.93932393 |
| 28 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.88786508 |
| 29 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.88325209 |
| 30 | MAF_26560356_Chip-Seq_TH1_Human | 1.86558800 |
| 31 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.83110433 |
| 32 | MYB_26560356_Chip-Seq_TH1_Human | 1.79513418 |
| 33 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.75386043 |
| 34 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.72481851 |
| 35 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.68673150 |
| 36 | UTX_26944678_Chip-Seq_JUKART_Human | 1.65742291 |
| 37 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.61780676 |
| 38 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.60611900 |
| 39 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.60344202 |
| 40 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.55272438 |
| 41 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.55107267 |
| 42 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.54133049 |
| 43 | * GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.52988304 |
| 44 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.48156714 |
| 45 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.45044271 |
| 46 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.44744739 |
| 47 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.44420235 |
| 48 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.43756410 |
| 49 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.43628380 |
| 50 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.38602582 |
| 51 | GATA3_26560356_Chip-Seq_TH2_Human | 1.37515190 |
| 52 | MAF_26560356_Chip-Seq_TH2_Human | 1.34825368 |
| 53 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.33269290 |
| 54 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.31407765 |
| 55 | GATA1_19941826_ChIP-Seq_K562_Human | 1.31398336 |
| 56 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.30598232 |
| 57 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.27746865 |
| 58 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.26622116 |
| 59 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.23895779 |
| 60 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.23435603 |
| 61 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.22561561 |
| 62 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.20491992 |
| 63 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.19916797 |
| 64 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.19126539 |
| 65 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.17275811 |
| 66 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.15639458 |
| 67 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.15139085 |
| 68 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.12694650 |
| 69 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.11452913 |
| 70 | SMRT_27268052_Chip-Seq_Bcells_Human | 1.10591338 |
| 71 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.09567720 |
| 72 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.09311055 |
| 73 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.08413076 |
| 74 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.08250818 |
| 75 | MYC_22102868_ChIP-Seq_BL_Human | 1.07630712 |
| 76 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.05870205 |
| 77 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.05803663 |
| 78 | SPI1_20517297_ChIP-Seq_HL60_Human | 1.04771471 |
| 79 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.04766064 |
| 80 | GATA2_19941826_ChIP-Seq_K562_Human | 1.04676487 |
| 81 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.03871096 |
| 82 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.00969345 |
| 83 | GATA1_19941827_ChIP-Seq_MEL86_Mouse | 1.00352196 |
| 84 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.98921127 |
| 85 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 0.97416318 |
| 86 | KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse | 0.96958757 |
| 87 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 0.96740194 |
| 88 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.94783269 |
| 89 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.94783269 |
| 90 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.94019657 |
| 91 | GATA1_22025678_ChIP-Seq_K562_Human | 0.91599273 |
| 92 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 0.91508970 |
| 93 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.89876521 |
| 94 | P300_27268052_Chip-Seq_Bcells_Human | 0.88575271 |
| 95 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.87824658 |
| 96 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.87692155 |
| 97 | DROSHA_22980978_ChIP-Seq_HELA_Human | 0.84106887 |
| 98 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.82503151 |
| 99 | RAC3_21632823_ChIP-Seq_H3396_Human | 0.80896890 |
| 100 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.80217065 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003724_increased_susceptibility_to | 5.30381346 |
| 2 | MP0003436_decreased_susceptibility_to | 3.95604966 |
| 3 | MP0003303_peritoneal_inflammation | 3.94153145 |
| 4 | MP0001835_abnormal_antigen_presentation | 3.72619840 |
| 5 | MP0002419_abnormal_innate_immunity | 3.20558918 |
| 6 | MP0005410_abnormal_fertilization | 2.97093644 |
| 7 | MP0009785_altered_susceptibility_to | 2.77967913 |
| 8 | MP0005025_abnormal_response_to | 2.74367536 |
| 9 | MP0001800_abnormal_humoral_immune | 2.63071478 |
| 10 | MP0005000_abnormal_immune_tolerance | 2.58979140 |
| 11 | MP0006082_CNS_inflammation | 2.58193549 |
| 12 | MP0005671_abnormal_response_to | 2.56478823 |
| 13 | MP0000685_abnormal_immune_system | 2.55013367 |
| 14 | MP0002723_abnormal_immune_serum | 2.43122497 |
| 15 | MP0002452_abnormal_antigen_presenting | 2.36353616 |
| 16 | MP0005387_immune_system_phenotype | 2.36084279 |
| 17 | MP0001790_abnormal_immune_system | 2.36084279 |
| 18 | MP0002132_abnormal_respiratory_system | 2.35964790 |
| 19 | MP0003172_abnormal_lysosome_physiology | 2.35340516 |
| 20 | MP0002420_abnormal_adaptive_immunity | 2.25225952 |
| 21 | MP0001819_abnormal_immune_cell | 2.22814970 |
| 22 | MP0001533_abnormal_skeleton_physiology | 2.22329315 |
| 23 | MP0005451_abnormal_body_composition | 2.21725912 |
| 24 | MP0008260_abnormal_autophagy | 2.18318568 |
| 25 | MP0002148_abnormal_hypersensitivity_rea | 2.14068702 |
| 26 | MP0003191_abnormal_cellular_cholesterol | 2.11132679 |
| 27 | MP0003828_pulmonary_edema | 2.05153154 |
| 28 | MP0003300_gastrointestinal_ulcer | 2.03228361 |
| 29 | MP0009278_abnormal_bone_marrow | 1.93279373 |
| 30 | MP0005464_abnormal_platelet_physiology | 1.92272180 |
| 31 | MP0009764_decreased_sensitivity_to | 1.87463439 |
| 32 | MP0002405_respiratory_system_inflammati | 1.80782586 |
| 33 | MP0005310_abnormal_salivary_gland | 1.69949428 |
| 34 | MP0000716_abnormal_immune_system | 1.65611504 |
| 35 | MP0003878_abnormal_ear_physiology | 1.65120414 |
| 36 | MP0005377_hearing/vestibular/ear_phenot | 1.65120414 |
| 37 | MP0001845_abnormal_inflammatory_respons | 1.64723021 |
| 38 | MP0004883_abnormal_blood_vessel | 1.60966927 |
| 39 | MP0000569_abnormal_digit_pigmentation | 1.60855141 |
| 40 | MP0002398_abnormal_bone_marrow | 1.60775715 |
| 41 | MP0005397_hematopoietic_system_phenotyp | 1.55678024 |
| 42 | MP0001545_abnormal_hematopoietic_system | 1.55678024 |
| 43 | MP0004947_skin_inflammation | 1.54795373 |
| 44 | MP0004510_myositis | 1.53940213 |
| 45 | MP0003075_altered_response_to | 1.42204350 |
| 46 | MP0005164_abnormal_response_to | 1.40968717 |
| 47 | MP0008469_abnormal_protein_level | 1.39812981 |
| 48 | MP0002722_abnormal_immune_system | 1.36615333 |
| 49 | MP0000689_abnormal_spleen_morphology | 1.33471321 |
| 50 | MP0010155_abnormal_intestine_physiology | 1.31692412 |
| 51 | MP0003763_abnormal_thymus_physiology | 1.29042808 |
| 52 | MP0002429_abnormal_blood_cell | 1.27681536 |
| 53 | MP0002998_abnormal_bone_remodeling | 1.26387861 |
| 54 | MP0002277_abnormal_respiratory_mucosa | 1.24216508 |
| 55 | MP0003183_abnormal_peptide_metabolism | 1.23665523 |
| 56 | MP0004381_abnormal_hair_follicle | 1.23218520 |
| 57 | MP0000465_gastrointestinal_hemorrhage | 1.23120674 |
| 58 | MP0005058_abnormal_lysosome_morphology | 1.17953271 |
| 59 | MP0008004_abnormal_stomach_pH | 1.17563902 |
| 60 | MP0003690_abnormal_glial_cell | 1.16414271 |
| 61 | MP0005166_decreased_susceptibility_to | 1.14847195 |
| 62 | MP0000703_abnormal_thymus_morphology | 1.11767843 |
| 63 | MP0000858_altered_metastatic_potential | 1.11667378 |
| 64 | MP0003866_abnormal_defecation | 1.10377736 |
| 65 | MP0009333_abnormal_splenocyte_physiolog | 1.06650637 |
| 66 | MP0002166_altered_tumor_susceptibility | 1.05066270 |
| 67 | MP0001851_eye_inflammation | 1.03467452 |
| 68 | MP0003656_abnormal_erythrocyte_physiolo | 1.03135254 |
| 69 | MP0002396_abnormal_hematopoietic_system | 1.03053961 |
| 70 | MP0000604_amyloidosis | 1.02978347 |
| 71 | MP0000343_altered_response_to | 1.02432780 |
| 72 | MP0001853_heart_inflammation | 0.99992791 |
| 73 | MP0000015_abnormal_ear_pigmentation | 0.98682054 |
| 74 | MP0003448_altered_tumor_morphology | 0.95719492 |
| 75 | MP0005390_skeleton_phenotype | 0.81649052 |
| 76 | MP0005167_abnormal_blood-brain_barrier | 0.80002800 |
| 77 | MP0009763_increased_sensitivity_to | 0.78204925 |
| 78 | MP0000249_abnormal_blood_vessel | 0.77300098 |
| 79 | MP0009765_abnormal_xenobiotic_induced | 0.75820037 |
| 80 | MP0004484_altered_response_of | 0.73590213 |
| 81 | MP0003011_delayed_dark_adaptation | 0.73396023 |
| 82 | MP0003698_abnormal_male_reproductive | 0.72964063 |
| 83 | MP0004808_abnormal_hematopoietic_stem | 0.69694063 |
| 84 | MP0008874_decreased_physiological_sensi | 0.69525181 |
| 85 | MP0002138_abnormal_hepatobiliary_system | 0.67992456 |
| 86 | MP0002006_tumorigenesis | 0.67744222 |
| 87 | MP0003045_fibrosis | 0.64087403 |
| 88 | MP0002332_abnormal_exercise_endurance | 0.63953795 |
| 89 | MP0003329_amyloid_beta_deposits | 0.62821726 |
| 90 | MP0001663_abnormal_digestive_system | 0.61659704 |
| 91 | MP0003091_abnormal_cell_migration | 0.59955595 |
| 92 | MP0003221_abnormal_cardiomyocyte_apopto | 0.58980238 |
| 93 | MP0005075_abnormal_melanosome_morpholog | 0.58747382 |
| 94 | MP0001765_abnormal_ion_homeostasis | 0.58153253 |
| 95 | MP0001929_abnormal_gametogenesis | 0.57906978 |
| 96 | MP0005376_homeostasis/metabolism_phenot | 0.57087697 |
| 97 | MP0004130_abnormal_muscle_cell | 0.56718810 |
| 98 | MP0003795_abnormal_bone_structure | 0.55798776 |
| 99 | MP0009115_abnormal_fat_cell | 0.53827853 |
| 100 | MP0005319_abnormal_enzyme/_coenzyme | 0.53403971 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Recurrent bacterial skin infections (HP:0005406) | 6.38809262 |
| 2 | Recurrent abscess formation (HP:0002722) | 6.26043047 |
| 3 | Eczematoid dermatitis (HP:0000976) | 6.21752632 |
| 4 | Myositis (HP:0100614) | 5.79302226 |
| 5 | Orchitis (HP:0100796) | 5.75468208 |
| 6 | Retrobulbar optic neuritis (HP:0100654) | 5.66198857 |
| 7 | Optic neuritis (HP:0100653) | 5.66198857 |
| 8 | Abnormality of macrophages (HP:0004311) | 5.47956263 |
| 9 | Recurrent gram-negative bacterial infections (HP:0005420) | 5.08613808 |
| 10 | Stomatitis (HP:0010280) | 4.66030887 |
| 11 | Gastrointestinal infarctions (HP:0005244) | 4.55320458 |
| 12 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.51867476 |
| 13 | Recurrent skin infections (HP:0001581) | 4.12789047 |
| 14 | Keratoconjunctivitis sicca (HP:0001097) | 4.09020349 |
| 15 | Obstructive lung disease (HP:0006536) | 4.04237253 |
| 16 | Chronic obstructive pulmonary disease (HP:0006510) | 4.04237253 |
| 17 | Gingivitis (HP:0000230) | 4.01817210 |
| 18 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 4.00098698 |
| 19 | Recurrent fungal infections (HP:0002841) | 3.95761396 |
| 20 | Keratoconjunctivitis (HP:0001096) | 3.75661779 |
| 21 | Mediastinal lymphadenopathy (HP:0100721) | 3.71461039 |
| 22 | Peritonitis (HP:0002586) | 3.64592344 |
| 23 | Meningitis (HP:0001287) | 3.60371207 |
| 24 | Amyloidosis (HP:0011034) | 3.47296239 |
| 25 | Recurrent cutaneous fungal infections (HP:0011370) | 3.39942287 |
| 26 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.39942287 |
| 27 | Encephalitis (HP:0002383) | 3.37899396 |
| 28 | Spontaneous hematomas (HP:0007420) | 3.30062028 |
| 29 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.29837742 |
| 30 | Vasculitis (HP:0002633) | 3.22132439 |
| 31 | Arterial thrombosis (HP:0004420) | 3.21828908 |
| 32 | Urticaria (HP:0001025) | 3.19447753 |
| 33 | Gingival bleeding (HP:0000225) | 3.19190649 |
| 34 | Chest pain (HP:0100749) | 3.12396048 |
| 35 | Hemoptysis (HP:0002105) | 3.09377855 |
| 36 | Episodic fever (HP:0001954) | 3.06627738 |
| 37 | Prolonged bleeding time (HP:0003010) | 3.00956645 |
| 38 | Hypochromic microcytic anemia (HP:0004840) | 2.94315467 |
| 39 | Severe visual impairment (HP:0001141) | 2.91639427 |
| 40 | Pulmonary infiltrates (HP:0002113) | 2.90376078 |
| 41 | T lymphocytopenia (HP:0005403) | 2.85339528 |
| 42 | Increased IgE level (HP:0003212) | 2.84620733 |
| 43 | Leukocytosis (HP:0001974) | 2.82079026 |
| 44 | Cellulitis (HP:0100658) | 2.77215549 |
| 45 | Abnormality of T cell number (HP:0011839) | 2.74650789 |
| 46 | Epistaxis (HP:0000421) | 2.61408152 |
| 47 | Anorexia (HP:0002039) | 2.60848006 |
| 48 | Resting tremor (HP:0002322) | 2.58272923 |
| 49 | Pulmonary embolism (HP:0002204) | 2.54277094 |
| 50 | Hypochromic anemia (HP:0001931) | 2.52419954 |
| 51 | Asymmetric septal hypertrophy (HP:0001670) | 2.52269559 |
| 52 | Gangrene (HP:0100758) | 2.50698365 |
| 53 | Abnormality of the peritoneum (HP:0002585) | 2.41745568 |
| 54 | Abnormality of T cells (HP:0002843) | 2.39613921 |
| 55 | Nasal polyposis (HP:0100582) | 2.36451714 |
| 56 | Inflammation of the large intestine (HP:0002037) | 2.36154903 |
| 57 | Recurrent pneumonia (HP:0006532) | 2.35933513 |
| 58 | Recurrent viral infections (HP:0004429) | 2.34459532 |
| 59 | Increased cerebral lipofuscin (HP:0011813) | 2.30814309 |
| 60 | Vertigo (HP:0002321) | 2.29871003 |
| 61 | Glomerulopathy (HP:0100820) | 2.29383467 |
| 62 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.28774646 |
| 63 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.28774646 |
| 64 | Abnormality of glycolipid metabolism (HP:0010969) | 2.28774646 |
| 65 | Absent/shortened dynein arms (HP:0200106) | 2.25315569 |
| 66 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.25315569 |
| 67 | Abnormality of the pleura (HP:0002103) | 2.22168231 |
| 68 | Osteomyelitis (HP:0002754) | 2.19231606 |
| 69 | Gastrointestinal inflammation (HP:0004386) | 2.18187512 |
| 70 | Slow saccadic eye movements (HP:0000514) | 2.16548921 |
| 71 | Postural instability (HP:0002172) | 2.14868112 |
| 72 | Abnormality of the endocardium (HP:0004306) | 2.12899706 |
| 73 | Granulocytopenia (HP:0001913) | 2.11172690 |
| 74 | Acute hepatic failure (HP:0006554) | 2.10573611 |
| 75 | Petechiae (HP:0000967) | 2.08265284 |
| 76 | Abnormality of T cell physiology (HP:0011840) | 2.06130753 |
| 77 | Acne (HP:0001061) | 1.99906689 |
| 78 | Sepsis (HP:0100806) | 1.99019307 |
| 79 | Increased IgM level (HP:0003496) | 1.95908168 |
| 80 | Abnormality of the nasal mucosa (HP:0000433) | 1.95745884 |
| 81 | Colitis (HP:0002583) | 1.95680449 |
| 82 | Loss of speech (HP:0002371) | 1.95640487 |
| 83 | Polyneuropathy (HP:0001271) | 1.95424567 |
| 84 | Autoimmune thrombocytopenia (HP:0001973) | 1.93341206 |
| 85 | Cheilitis (HP:0100825) | 1.89985302 |
| 86 | Microcytic anemia (HP:0001935) | 1.89651141 |
| 87 | Hepatosplenomegaly (HP:0001433) | 1.89246633 |
| 88 | Segmental peripheral demyelination/remyelination (HP:0003481) | 1.88475609 |
| 89 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 1.84867327 |
| 90 | Keratitis (HP:0000491) | 1.83401141 |
| 91 | Eosinophilia (HP:0001880) | 1.82346236 |
| 92 | Recurrent lower respiratory tract infections (HP:0002783) | 1.81648046 |
| 93 | Hypoplasia of the thymus (HP:0000778) | 1.81272418 |
| 94 | Pustule (HP:0200039) | 1.80505654 |
| 95 | Purpura (HP:0000979) | 1.77330009 |
| 96 | Amaurosis fugax (HP:0100576) | 1.76825906 |
| 97 | Increased serum ferritin (HP:0003281) | 1.76657193 |
| 98 | Myocardial infarction (HP:0001658) | 1.76334275 |
| 99 | Skin ulcer (HP:0200042) | 1.74343022 |
| 100 | Hypergammaglobulinemia (HP:0010702) | 1.73671489 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | RIPK4 | 5.34588252 |
| 2 | BLK | 3.55512017 |
| 3 | IRAK4 | 3.35807987 |
| 4 | MAP2K3 | 2.97043068 |
| 5 | CSK | 2.73087296 |
| 6 | MAP4K1 | 2.65651209 |
| 7 | TYK2 | 2.53705348 |
| 8 | FES | 2.22219589 |
| 9 | GRK6 | 2.03496400 |
| 10 | ERN1 | 2.02324904 |
| 11 | ZAP70 | 1.97643824 |
| 12 | JAK3 | 1.87306492 |
| 13 | FGR | 1.78936276 |
| 14 | TXK | 1.77913889 |
| 15 | MAP3K3 | 1.75815840 |
| 16 | KSR2 | 1.75038562 |
| 17 | TNK2 | 1.74955964 |
| 18 | EPHB1 | 1.73933745 |
| 19 | MAP3K14 | 1.70895203 |
| 20 | MAP3K11 | 1.67898373 |
| 21 | PIK3CG | 1.62549034 |
| 22 | SYK | 1.62338832 |
| 23 | HCK | 1.55987055 |
| 24 | BTK | 1.55359622 |
| 25 | JAK2 | 1.52050927 |
| 26 | TAOK1 | 1.50932453 |
| 27 | PRPF4B | 1.45146831 |
| 28 | IKBKE | 1.45005322 |
| 29 | MAP3K1 | 1.44978807 |
| 30 | TAOK3 | 1.40905013 |
| 31 | MAP3K2 | 1.40162932 |
| 32 | IRAK1 | 1.37186047 |
| 33 | PLK4 | 1.33724574 |
| 34 | LYN | 1.31452241 |
| 35 | PDK1 | 1.31395452 |
| 36 | MAP3K13 | 1.29640370 |
| 37 | IRAK2 | 1.28837086 |
| 38 | BMPR2 | 1.25933084 |
| 39 | PDPK1 | 1.24364958 |
| 40 | YES1 | 1.22935747 |
| 41 | STK38 | 1.17630938 |
| 42 | MATK | 1.15382383 |
| 43 | JAK1 | 1.14060641 |
| 44 | WNK1 | 1.10712869 |
| 45 | TBK1 | 1.08770156 |
| 46 | CSF1R | 1.04583643 |
| 47 | DDR2 | 1.00298530 |
| 48 | KIT | 0.99050607 |
| 49 | PTK2B | 0.98904502 |
| 50 | MARK3 | 0.96286999 |
| 51 | MARK2 | 0.93193678 |
| 52 | LCK | 0.92463060 |
| 53 | TEC | 0.90247915 |
| 54 | IKBKB | 0.89083283 |
| 55 | ITK | 0.88375291 |
| 56 | MAP3K6 | 0.85199170 |
| 57 | SIK2 | 0.82260334 |
| 58 | SIK3 | 0.78733238 |
| 59 | DYRK1B | 0.77327863 |
| 60 | MAP2K4 | 0.75597610 |
| 61 | BRD4 | 0.70157074 |
| 62 | CDK19 | 0.70069503 |
| 63 | TESK1 | 0.69247512 |
| 64 | SGK3 | 0.68208990 |
| 65 | STK10 | 0.68110863 |
| 66 | SGK2 | 0.63904165 |
| 67 | GRK7 | 0.63102389 |
| 68 | TGFBR2 | 0.61201561 |
| 69 | CAMK1G | 0.61130801 |
| 70 | TESK2 | 0.58711194 |
| 71 | PTK6 | 0.57682867 |
| 72 | TAOK2 | 0.57499007 |
| 73 | MAP3K5 | 0.55970203 |
| 74 | FYN | 0.55349443 |
| 75 | CAMK1D | 0.55245005 |
| 76 | LRRK2 | 0.54688293 |
| 77 | FGFR3 | 0.53329008 |
| 78 | STK11 | 0.52290627 |
| 79 | RPS6KC1 | 0.51819847 |
| 80 | RPS6KL1 | 0.51819847 |
| 81 | DAPK2 | 0.50135514 |
| 82 | RPS6KA6 | 0.47506121 |
| 83 | RAF1 | 0.46450827 |
| 84 | EPHA3 | 0.46049840 |
| 85 | PRKCQ | 0.41679971 |
| 86 | INSRR | 0.41504130 |
| 87 | MAP2K6 | 0.41245323 |
| 88 | MAP3K7 | 0.40744331 |
| 89 | CAMK4 | 0.40018576 |
| 90 | PRKG2 | 0.39860806 |
| 91 | MAPK7 | 0.39261526 |
| 92 | PRKCZ | 0.39044377 |
| 93 | MAPK12 | 0.39005637 |
| 94 | CAMKK2 | 0.38322093 |
| 95 | RET | 0.38169819 |
| 96 | PLK2 | 0.37692154 |
| 97 | ACVR1B | 0.36702580 |
| 98 | DYRK3 | 0.36421621 |
| 99 | KSR1 | 0.36156696 |
| 100 | MAPKAPK2 | 0.34896995 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Leishmaniasis_Homo sapiens_hsa05140 | 3.21837507 |
| 2 | Osteoclast differentiation_Homo sapiens_hsa04380 | 3.08850372 |
| 3 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.79437704 |
| 4 | Tuberculosis_Homo sapiens_hsa05152 | 2.34866796 |
| 5 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.24407957 |
| 6 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 2.22466737 |
| 7 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 2.20203144 |
| 8 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 2.14406654 |
| 9 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.13237418 |
| 10 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 2.06525661 |
| 11 | Allograft rejection_Homo sapiens_hsa05330 | 2.05714766 |
| 12 | Legionellosis_Homo sapiens_hsa05134 | 1.94609016 |
| 13 | Malaria_Homo sapiens_hsa05144 | 1.93690050 |
| 14 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.89012742 |
| 15 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.88104610 |
| 16 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.70964603 |
| 17 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.69275935 |
| 18 | Influenza A_Homo sapiens_hsa05164 | 1.68160912 |
| 19 | Measles_Homo sapiens_hsa05162 | 1.67729431 |
| 20 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.65005162 |
| 21 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.61054372 |
| 22 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.60106586 |
| 23 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.59469391 |
| 24 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.57601506 |
| 25 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.57073073 |
| 26 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.50022550 |
| 27 | Phagosome_Homo sapiens_hsa04145 | 1.49603927 |
| 28 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.39970270 |
| 29 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.37900019 |
| 30 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.37733713 |
| 31 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.30275396 |
| 32 | Viral myocarditis_Homo sapiens_hsa05416 | 1.29301653 |
| 33 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.28405457 |
| 34 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.23794659 |
| 35 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.20081319 |
| 36 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.18373607 |
| 37 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.17998165 |
| 38 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.16520205 |
| 39 | Platelet activation_Homo sapiens_hsa04611 | 1.13961516 |
| 40 | Hepatitis B_Homo sapiens_hsa05161 | 1.13748814 |
| 41 | Pertussis_Homo sapiens_hsa05133 | 1.13458116 |
| 42 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.05385852 |
| 43 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.03095308 |
| 44 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 1.01440917 |
| 45 | Other glycan degradation_Homo sapiens_hsa00511 | 1.00452362 |
| 46 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.98633373 |
| 47 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.98448594 |
| 48 | Asthma_Homo sapiens_hsa05310 | 0.98044787 |
| 49 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.97280320 |
| 50 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.95289580 |
| 51 | Salmonella infection_Homo sapiens_hsa05132 | 0.95244358 |
| 52 | Lysosome_Homo sapiens_hsa04142 | 0.93048128 |
| 53 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.93033668 |
| 54 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.91342212 |
| 55 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.88975612 |
| 56 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.88823896 |
| 57 | Endocytosis_Homo sapiens_hsa04144 | 0.88635112 |
| 58 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.85995046 |
| 59 | Hepatitis C_Homo sapiens_hsa05160 | 0.85208187 |
| 60 | Shigellosis_Homo sapiens_hsa05131 | 0.84135175 |
| 61 | Apoptosis_Homo sapiens_hsa04210 | 0.83609902 |
| 62 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.83452856 |
| 63 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.81282648 |
| 64 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.78152835 |
| 65 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.74757192 |
| 66 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.74668796 |
| 67 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.73684902 |
| 68 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.73259634 |
| 69 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.72449708 |
| 70 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.70443376 |
| 71 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.67851693 |
| 72 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.67362938 |
| 73 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.64849632 |
| 74 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.64486995 |
| 75 | Amoebiasis_Homo sapiens_hsa05146 | 0.64407481 |
| 76 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.64182468 |
| 77 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.62058965 |
| 78 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.60436358 |
| 79 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.58825852 |
| 80 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.57560140 |
| 81 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.55043941 |
| 82 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.54745001 |
| 83 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.53948689 |
| 84 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.52628783 |
| 85 | Olfactory transduction_Homo sapiens_hsa04740 | 0.52490318 |
| 86 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.51716498 |
| 87 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.51030442 |
| 88 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.50395422 |
| 89 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.49674318 |
| 90 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.49500096 |
| 91 | Endometrial cancer_Homo sapiens_hsa05213 | 0.48793545 |
| 92 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.48713657 |
| 93 | Insulin resistance_Homo sapiens_hsa04931 | 0.48083509 |
| 94 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.45336403 |
| 95 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.44749963 |
| 96 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.37147968 |
| 97 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.36160265 |
| 98 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.35200784 |
| 99 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.34898960 |
| 100 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.33907486 |

