Rank | Gene Set | Z-score |
---|---|---|
1 | mitotic metaphase plate congression (GO:0007080) | 5.77535418 |
2 | protein localization to kinetochore (GO:0034501) | 5.55607343 |
3 | kinetochore organization (GO:0051383) | 5.13566894 |
4 | protein localization to chromosome, centromeric region (GO:0071459) | 5.11089484 |
5 | CENP-A containing nucleosome assembly (GO:0034080) | 5.10515241 |
6 | DNA replication checkpoint (GO:0000076) | 5.03255526 |
7 | metaphase plate congression (GO:0051310) | 5.02045374 |
8 | chromatin remodeling at centromere (GO:0031055) | 4.97676915 |
9 | attachment of spindle microtubules to kinetochore (GO:0008608) | 4.77808191 |
10 | kinetochore assembly (GO:0051382) | 4.71190658 |
11 | mitotic chromosome condensation (GO:0007076) | 4.70521071 |
12 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.66048478 |
13 | mitotic sister chromatid segregation (GO:0000070) | 4.62183199 |
14 | establishment of chromosome localization (GO:0051303) | 4.57653993 |
15 | regulation of spindle organization (GO:0090224) | 4.57018335 |
16 | DNA replication-independent nucleosome organization (GO:0034724) | 4.53878646 |
17 | DNA replication-independent nucleosome assembly (GO:0006336) | 4.53878646 |
18 | DNA replication initiation (GO:0006270) | 4.53741997 |
19 | telomere maintenance via semi-conservative replication (GO:0032201) | 4.47604112 |
20 | DNA strand elongation (GO:0022616) | 4.42400600 |
21 | replication fork processing (GO:0031297) | 4.32474035 |
22 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 4.30964551 |
23 | histone exchange (GO:0043486) | 4.30552017 |
24 | sister chromatid segregation (GO:0000819) | 4.18109948 |
25 | regulation of DNA endoreduplication (GO:0032875) | 4.16692726 |
26 | telomere maintenance via recombination (GO:0000722) | 4.09828432 |
27 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 4.03452359 |
28 | DNA replication-dependent nucleosome organization (GO:0034723) | 4.00816798 |
29 | DNA replication-dependent nucleosome assembly (GO:0006335) | 4.00816798 |
30 | mitotic recombination (GO:0006312) | 4.00538403 |
31 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 4.00306063 |
32 | meiotic chromosome segregation (GO:0045132) | 4.00283947 |
33 | mitotic nuclear envelope disassembly (GO:0007077) | 3.99986518 |
34 | spindle checkpoint (GO:0031577) | 3.95123097 |
35 | regulation of mitotic spindle organization (GO:0060236) | 3.94243875 |
36 | synapsis (GO:0007129) | 3.84598851 |
37 | maturation of SSU-rRNA (GO:0030490) | 3.84298992 |
38 | DNA unwinding involved in DNA replication (GO:0006268) | 3.76674432 |
39 | regulation of chromosome segregation (GO:0051983) | 3.74328416 |
40 | nucleobase biosynthetic process (GO:0046112) | 3.71588481 |
41 | protein localization to chromosome (GO:0034502) | 3.71426194 |
42 | nuclear envelope disassembly (GO:0051081) | 3.70297373 |
43 | membrane disassembly (GO:0030397) | 3.70297373 |
44 | telomere maintenance via telomere lengthening (GO:0010833) | 3.70095769 |
45 | negative regulation of chromosome segregation (GO:0051985) | 3.68777060 |
46 | DNA double-strand break processing (GO:0000729) | 3.67235549 |
47 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 3.67235178 |
48 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 3.67235178 |
49 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 3.67235178 |
50 | negative regulation of sister chromatid segregation (GO:0033046) | 3.67235178 |
51 | spindle assembly checkpoint (GO:0071173) | 3.65260063 |
52 | regulation of mitotic metaphase/anaphase transition (GO:0030071) | 3.62394722 |
53 | nuclear pore organization (GO:0006999) | 3.62115916 |
54 | purine nucleobase biosynthetic process (GO:0009113) | 3.61825259 |
55 | regulation of centriole replication (GO:0046599) | 3.60830033 |
56 | positive regulation of chromosome segregation (GO:0051984) | 3.60086139 |
57 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 3.59466364 |
58 | regulation of metaphase/anaphase transition of cell cycle (GO:1902099) | 3.56501558 |
59 | * chromosome segregation (GO:0007059) | 3.56449550 |
60 | mitotic spindle assembly checkpoint (GO:0007094) | 3.54782543 |
61 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.52410788 |
62 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.52410788 |
63 | mitotic spindle checkpoint (GO:0071174) | 3.51126941 |
64 | DNA ligation (GO:0006266) | 3.49948222 |
65 | resolution of meiotic recombination intermediates (GO:0000712) | 3.49524512 |
66 | protein K6-linked ubiquitination (GO:0085020) | 3.47610208 |
67 | ribosomal large subunit biogenesis (GO:0042273) | 3.45001105 |
68 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 3.43159275 |
69 | nuclear pore complex assembly (GO:0051292) | 3.43139989 |
70 | chromatin assembly or disassembly (GO:0006333) | 3.42480112 |
71 | regulation of mitotic sister chromatid separation (GO:0010965) | 3.42108170 |
72 | regulation of mitotic sister chromatid segregation (GO:0033047) | 3.42108170 |
73 | regulation of sister chromatid segregation (GO:0033045) | 3.42108170 |
74 | ribosomal small subunit assembly (GO:0000028) | 3.41093539 |
75 | recombinational repair (GO:0000725) | 3.39893227 |
76 | spliceosomal snRNP assembly (GO:0000387) | 3.38827981 |
77 | DNA deamination (GO:0045006) | 3.38252504 |
78 | viral transcription (GO:0019083) | 3.37869096 |
79 | translational termination (GO:0006415) | 3.37465983 |
80 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.36585167 |
81 | double-strand break repair via homologous recombination (GO:0000724) | 3.35698299 |
82 | ribosomal small subunit biogenesis (GO:0042274) | 3.29557301 |
83 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.29539307 |
84 | ATP-dependent chromatin remodeling (GO:0043044) | 3.28274328 |
85 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.28258882 |
86 | regulation of sister chromatid cohesion (GO:0007063) | 3.28200555 |
87 | ribosome biogenesis (GO:0042254) | 3.27192785 |
88 | formation of translation preinitiation complex (GO:0001731) | 3.26040193 |
89 | ribosome assembly (GO:0042255) | 3.23751732 |
90 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.21197900 |
91 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.21197900 |
92 | centriole replication (GO:0007099) | 3.19552340 |
93 | chromosome condensation (GO:0030261) | 3.19108805 |
94 | positive regulation of mitotic sister chromatid separation (GO:1901970) | 3.18734945 |
95 | positive regulation of mitotic metaphase/anaphase transition (GO:0045842) | 3.18734945 |
96 | positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101) | 3.18734945 |
97 | microtubule depolymerization (GO:0007019) | 3.18353383 |
98 | postreplication repair (GO:0006301) | 3.17473736 |
99 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.16816819 |
100 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.16190221 |
101 | rRNA processing (GO:0006364) | 3.14879954 |
102 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 3.14607057 |
103 | regulation of exit from mitosis (GO:0007096) | 3.14498393 |
104 | regulation of centrosome cycle (GO:0046605) | 3.13127498 |
105 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.12585704 |
106 | DNA strand renaturation (GO:0000733) | 3.11962782 |
107 | translational initiation (GO:0006413) | 3.11701207 |
108 | * mitotic cell cycle (GO:0000278) | 3.11057785 |
109 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.10347349 |
110 | transcription-coupled nucleotide-excision repair (GO:0006283) | 3.09760915 |
111 | spliceosomal complex assembly (GO:0000245) | 3.08528603 |
112 | mitotic sister chromatid cohesion (GO:0007064) | 3.08195481 |
113 | mitotic G2/M transition checkpoint (GO:0044818) | 3.05370442 |
114 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.04573764 |
115 | rRNA metabolic process (GO:0016072) | 3.04556573 |
116 | proteasome assembly (GO:0043248) | 3.03097311 |
117 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 3.02760845 |
118 | translational elongation (GO:0006414) | 3.02555622 |
119 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.02265940 |
120 | centrosome organization (GO:0051297) | 3.00394499 |
121 | rRNA modification (GO:0000154) | 2.97611833 |
122 | G1/S transition of mitotic cell cycle (GO:0000082) | 2.95550519 |
123 | cell cycle G1/S phase transition (GO:0044843) | 2.95550519 |
124 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.93204924 |
125 | cullin deneddylation (GO:0010388) | 2.91384630 |
126 | double-strand break repair via nonhomologous end joining (GO:0006303) | 2.91037905 |
127 | non-recombinational repair (GO:0000726) | 2.91037905 |
128 | maturation of 5.8S rRNA (GO:0000460) | 2.87403841 |
129 | regulation of centrosome duplication (GO:0010824) | 2.86459152 |
130 | translesion synthesis (GO:0019985) | 2.85740746 |
131 | isotype switching (GO:0045190) | 2.85428223 |
132 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 2.85428223 |
133 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 2.85428223 |
134 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 2.80695248 |
135 | DNA recombination (GO:0006310) | 2.79090086 |
136 | reciprocal DNA recombination (GO:0035825) | 2.76137841 |
Rank | Gene Set | Z-score |
---|---|---|
1 | E2F7_22180533_ChIP-Seq_HELA_Human | 9.00666587 |
2 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 6.04124673 |
3 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 4.37525401 |
4 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 4.10013558 |
5 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.09791349 |
6 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.55616240 |
7 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.34799450 |
8 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.94097728 |
9 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.92739770 |
10 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.85249994 |
11 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.78456371 |
12 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.77767923 |
13 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.76316717 |
14 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.75827712 |
15 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.70011406 |
16 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.69732861 |
17 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.69620742 |
18 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.47119563 |
19 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.38456394 |
20 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.37120028 |
21 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.35506342 |
22 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.33153645 |
23 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.31070561 |
24 | VDR_22108803_ChIP-Seq_LS180_Human | 2.22070109 |
25 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 2.18024646 |
26 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.16210997 |
27 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 2.12855410 |
28 | EWS_26573619_Chip-Seq_HEK293_Human | 2.04183685 |
29 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.02822212 |
30 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.01126918 |
31 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.96033720 |
32 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.91746205 |
33 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.91611645 |
34 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.88380429 |
35 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.87085473 |
36 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.86730740 |
37 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.80718702 |
38 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.79714339 |
39 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.79618723 |
40 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.79500693 |
41 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.77843116 |
42 | FUS_26573619_Chip-Seq_HEK293_Human | 1.75660919 |
43 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.72252232 |
44 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.67591812 |
45 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.64655257 |
46 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.63435424 |
47 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.61465601 |
48 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.61331001 |
49 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.58301658 |
50 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.56195253 |
51 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.53428670 |
52 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.52106294 |
53 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.52068205 |
54 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.49590977 |
55 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.48601720 |
56 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.46556839 |
57 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.44789518 |
58 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.44017386 |
59 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.43943554 |
60 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.41804824 |
61 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.39055307 |
62 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.38551004 |
63 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.35172433 |
64 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.31069408 |
65 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.30392618 |
66 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.30333909 |
67 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.27379288 |
68 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.26121100 |
69 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.25199298 |
70 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.22690637 |
71 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.21600818 |
72 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.20253327 |
73 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 1.18783023 |
74 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.16104174 |
75 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.15789092 |
76 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.15439488 |
77 | MYC_22102868_ChIP-Seq_BL_Human | 1.12246948 |
78 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.11191778 |
79 | P300_19829295_ChIP-Seq_ESCs_Human | 1.10734015 |
80 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.10668218 |
81 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.10046971 |
82 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.09940508 |
83 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 1.08182171 |
84 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.07564636 |
85 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.06837758 |
86 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.06523056 |
87 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.05911653 |
88 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.05136982 |
89 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.05111941 |
90 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.04241266 |
91 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.03828884 |
92 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.02027573 |
93 | CREM_20920259_ChIP-Seq_GC1-SPG_Mouse | 1.00451501 |
94 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.99979649 |
95 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.97819013 |
96 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.95611167 |
97 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.95589884 |
98 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.95322776 |
99 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.95257752 |
100 | TAF15_26573619_Chip-Seq_HEK293_Human | 0.94491851 |
101 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.94476505 |
102 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 0.93037485 |
103 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 0.92912837 |
104 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.92148325 |
105 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.90965148 |
106 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 0.90150308 |
107 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.90029092 |
108 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 0.88510356 |
109 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.87960137 |
110 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.86770148 |
111 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 0.84917383 |
112 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.84139024 |
113 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.83720496 |
114 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.80259784 |
115 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 0.78813108 |
116 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.78436913 |
117 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.78436913 |
118 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.78218719 |
119 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.78185644 |
120 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.77914983 |
121 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.77914983 |
122 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.77403741 |
123 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.77049929 |
124 | VDR_21846776_ChIP-Seq_THP-1_Human | 0.76410927 |
125 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.76091571 |
126 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 0.75204282 |
127 | GBX2_23144817_ChIP-Seq_PC3_Human | 0.74893935 |
128 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.74816883 |
129 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.74816883 |
130 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.74654744 |
131 | SPI1_23547873_ChIP-Seq_NB4_Human | 0.74372366 |
132 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.74172830 |
133 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.74066862 |
134 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.72836239 |
135 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.72071486 |
136 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.71937217 |
137 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.70845508 |
138 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 0.70553488 |
139 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.68746106 |
140 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 0.67871689 |
141 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.67300269 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003693_abnormal_embryo_hatching | 6.44325194 |
2 | MP0003111_abnormal_nucleus_morphology | 5.20697446 |
3 | MP0010094_abnormal_chromosome_stability | 4.97221546 |
4 | MP0004957_abnormal_blastocyst_morpholog | 4.78153259 |
5 | MP0003077_abnormal_cell_cycle | 4.51085668 |
6 | MP0008057_abnormal_DNA_replication | 4.03740219 |
7 | MP0008058_abnormal_DNA_repair | 3.33488260 |
8 | MP0008932_abnormal_embryonic_tissue | 3.05559616 |
9 | MP0008007_abnormal_cellular_replicative | 3.04511085 |
10 | MP0000372_irregular_coat_pigmentation | 2.78219825 |
11 | MP0008877_abnormal_DNA_methylation | 2.56283174 |
12 | MP0001730_embryonic_growth_arrest | 2.37593625 |
13 | MP0003718_maternal_effect | 2.36482941 |
14 | MP0000350_abnormal_cell_proliferation | 2.30818296 |
15 | MP0003123_paternal_imprinting | 2.23371202 |
16 | MP0002938_white_spotting | 2.14610106 |
17 | MP0003786_premature_aging | 2.06930215 |
18 | MP0009697_abnormal_copulation | 1.99750877 |
19 | MP0006072_abnormal_retinal_apoptosis | 1.87746154 |
20 | MP0010307_abnormal_tumor_latency | 1.87153516 |
21 | MP0005380_embryogenesis_phenotype | 1.84373865 |
22 | MP0001672_abnormal_embryogenesis/_devel | 1.84373865 |
23 | MP0002396_abnormal_hematopoietic_system | 1.78426865 |
24 | MP0001697_abnormal_embryo_size | 1.76611995 |
25 | MP0003195_calcinosis | 1.75087913 |
26 | MP0002085_abnormal_embryonic_tissue | 1.61147926 |
27 | MP0002080_prenatal_lethality | 1.58379589 |
28 | MP0003984_embryonic_growth_retardation | 1.56329036 |
29 | MP0002210_abnormal_sex_determination | 1.55391285 |
30 | MP0002088_abnormal_embryonic_growth/wei | 1.53159007 |
31 | MP0000313_abnormal_cell_death | 1.50111463 |
32 | MP0005171_absent_coat_pigmentation | 1.48051884 |
33 | MP0000490_abnormal_crypts_of | 1.47577925 |
34 | MP0003315_abnormal_perineum_morphology | 1.47161232 |
35 | MP0010030_abnormal_orbit_morphology | 1.42339726 |
36 | MP0002095_abnormal_skin_pigmentation | 1.40847306 |
37 | MP0002019_abnormal_tumor_incidence | 1.36639379 |
38 | MP0002084_abnormal_developmental_patter | 1.35456091 |
39 | MP0006292_abnormal_olfactory_placode | 1.34941082 |
40 | MP0002086_abnormal_extraembryonic_tissu | 1.34800569 |
41 | MP0001145_abnormal_male_reproductive | 1.33100090 |
42 | MP0001929_abnormal_gametogenesis | 1.32013490 |
43 | MP0005551_abnormal_eye_electrophysiolog | 1.31156407 |
44 | MP0005174_abnormal_tail_pigmentation | 1.30899038 |
45 | MP0005075_abnormal_melanosome_morpholog | 1.30896420 |
46 | MP0005253_abnormal_eye_physiology | 1.28960903 |
47 | MP0004808_abnormal_hematopoietic_stem | 1.27938064 |
48 | MP0008995_early_reproductive_senescence | 1.27749284 |
49 | MP0000631_abnormal_neuroendocrine_gland | 1.26731869 |
50 | MP0000427_abnormal_hair_cycle | 1.25614747 |
51 | MP0003646_muscle_fatigue | 1.25028399 |
52 | MP0010352_gastrointestinal_tract_polyps | 1.24333278 |
53 | MP0000569_abnormal_digit_pigmentation | 1.23976931 |
54 | MP0009053_abnormal_anal_canal | 1.23743290 |
55 | MP0008872_abnormal_physiological_respon | 1.23260498 |
56 | MP0000653_abnormal_sex_gland | 1.20517212 |
57 | MP0003121_genomic_imprinting | 1.17755062 |
58 | MP0005076_abnormal_cell_differentiation | 1.16700497 |
59 | MP0006035_abnormal_mitochondrial_morpho | 1.16392381 |
60 | MP0001529_abnormal_vocalization | 1.13430614 |
61 | MP0003567_abnormal_fetal_cardiomyocyte | 1.13279009 |
62 | MP0005408_hypopigmentation | 1.13253751 |
63 | MP0004197_abnormal_fetal_growth/weight/ | 1.12946624 |
64 | MP0009333_abnormal_splenocyte_physiolog | 1.12869703 |
65 | MP0002736_abnormal_nociception_after | 1.09123985 |
66 | MP0003890_abnormal_embryonic-extraembry | 1.07222435 |
67 | MP0001119_abnormal_female_reproductive | 1.06246019 |
68 | MP0001545_abnormal_hematopoietic_system | 1.05292562 |
69 | MP0005397_hematopoietic_system_phenotyp | 1.05292562 |
70 | MP0002234_abnormal_pharynx_morphology | 1.04844537 |
71 | MP0002837_dystrophic_cardiac_calcinosis | 1.04557659 |
72 | MP0002102_abnormal_ear_morphology | 1.04260142 |
73 | MP0005084_abnormal_gallbladder_morpholo | 1.03382382 |
74 | MP0003937_abnormal_limbs/digits/tail_de | 1.02724606 |
75 | MP0009379_abnormal_foot_pigmentation | 1.01430684 |
76 | MP0002160_abnormal_reproductive_system | 1.01378161 |
77 | MP0001293_anophthalmia | 1.00318923 |
78 | MP0000647_abnormal_sebaceous_gland | 0.99269478 |
79 | MP0000015_abnormal_ear_pigmentation | 0.98403488 |
80 | MP0000703_abnormal_thymus_morphology | 0.92502031 |
81 | MP0003941_abnormal_skin_development | 0.91766541 |
82 | MP0005389_reproductive_system_phenotype | 0.89176255 |
83 | MP0002277_abnormal_respiratory_mucosa | 0.88851352 |
84 | MP0003950_abnormal_plasma_membrane | 0.88306853 |
85 | MP0001485_abnormal_pinna_reflex | 0.86872603 |
86 | MP0001324_abnormal_eye_pigmentation | 0.85895502 |
87 | MP0005645_abnormal_hypothalamus_physiol | 0.85796540 |
88 | MP0003806_abnormal_nucleotide_metabolis | 0.82956256 |
89 | MP0002638_abnormal_pupillary_reflex | 0.82767407 |
90 | MP0002111_abnormal_tail_morphology | 0.82188956 |
91 | MP0003119_abnormal_digestive_system | 0.81970561 |
92 | MP0002233_abnormal_nose_morphology | 0.81231967 |
93 | MP0003221_abnormal_cardiomyocyte_apopto | 0.81062444 |
94 | MP0003938_abnormal_ear_development | 0.81010686 |
95 | MP0002132_abnormal_respiratory_system | 0.80928506 |
96 | MP0002751_abnormal_autonomic_nervous | 0.80456136 |
97 | MP0005391_vision/eye_phenotype | 0.79770349 |
98 | MP0009672_abnormal_birth_weight | 0.79290554 |
99 | MP0005379_endocrine/exocrine_gland_phen | 0.79107067 |
100 | MP0002398_abnormal_bone_marrow | 0.78215207 |
101 | MP0000858_altered_metastatic_potential | 0.76950656 |
102 | MP0002722_abnormal_immune_system | 0.76868611 |
103 | MP0001919_abnormal_reproductive_system | 0.75431495 |
104 | MP0000689_abnormal_spleen_morphology | 0.74681686 |
105 | MP0001968_abnormal_touch/_nociception | 0.74071098 |
106 | MP0003656_abnormal_erythrocyte_physiolo | 0.73939834 |
107 | MP0003699_abnormal_female_reproductive | 0.73294401 |
108 | MP0005384_cellular_phenotype | 0.72693279 |
109 | MP0001286_abnormal_eye_development | 0.72544975 |
110 | MP0005621_abnormal_cell_physiology | 0.71924475 |
111 | MP0003943_abnormal_hepatobiliary_system | 0.71480035 |
112 | MP0000358_abnormal_cell_content/ | 0.70375054 |
113 | MP0003186_abnormal_redox_activity | 0.69604582 |
114 | MP0006054_spinal_hemorrhage | 0.69371292 |
115 | MP0009046_muscle_twitch | 0.68486379 |
116 | MP0005195_abnormal_posterior_eye | 0.68353891 |
117 | MP0003763_abnormal_thymus_physiology | 0.66922333 |
118 | MP0004142_abnormal_muscle_tone | 0.64951864 |
119 | MP0000428_abnormal_craniofacial_morphol | 0.64270494 |
120 | MP0003698_abnormal_male_reproductive | 0.64149741 |
121 | MP0005395_other_phenotype | 0.63590643 |
122 | MP0003936_abnormal_reproductive_system | 0.63351590 |
123 | MP0002161_abnormal_fertility/fecundity | 0.63034270 |
124 | MP0002653_abnormal_ependyma_morphology | 0.62844266 |
125 | MP0003136_yellow_coat_color | 0.60905044 |
126 | MP0003755_abnormal_palate_morphology | 0.59735524 |
127 | MP0002429_abnormal_blood_cell | 0.59462151 |
128 | MP0000432_abnormal_head_morphology | 0.56365425 |
129 | MP0008789_abnormal_olfactory_epithelium | 0.56057544 |
130 | MP0001727_abnormal_embryo_implantation | 0.55718105 |
131 | MP0009703_decreased_birth_body | 0.54773322 |
132 | MP0004133_heterotaxia | 0.53874758 |
133 | MP0002092_abnormal_eye_morphology | 0.53344882 |
134 | MP0005023_abnormal_wound_healing | 0.53164143 |
135 | MP0006036_abnormal_mitochondrial_physio | 0.53046380 |
136 | MP0001915_intracranial_hemorrhage | 0.51861450 |
137 | MP0004147_increased_porphyrin_level | 0.50652927 |
138 | MP0003935_abnormal_craniofacial_develop | 0.50584769 |
139 | MP0000049_abnormal_middle_ear | 0.48853229 |
140 | MP0002163_abnormal_gland_morphology | 0.48510621 |
141 | MP0000537_abnormal_urethra_morphology | 0.46078325 |
142 | MP0009278_abnormal_bone_marrow | 0.45733777 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Birth length less than 3rd percentile (HP:0003561) | 5.62488651 |
2 | Breast hypoplasia (HP:0003187) | 4.73685499 |
3 | Chromsome breakage (HP:0040012) | 4.58069587 |
4 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 4.50653964 |
5 | Reticulocytopenia (HP:0001896) | 4.36892148 |
6 | Patellar aplasia (HP:0006443) | 4.27182033 |
7 | Aplasia/Hypoplasia of the patella (HP:0006498) | 4.02387307 |
8 | Carpal bone hypoplasia (HP:0001498) | 3.82147954 |
9 | Meckel diverticulum (HP:0002245) | 3.81631243 |
10 | Abnormality of the preputium (HP:0100587) | 3.65571501 |
11 | Abnormality of the ileum (HP:0001549) | 3.60755420 |
12 | Abnormality of chromosome stability (HP:0003220) | 3.58893896 |
13 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.57689307 |
14 | Abnormal number of erythroid precursors (HP:0012131) | 3.55493482 |
15 | Oral leukoplakia (HP:0002745) | 3.48873833 |
16 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 3.35162787 |
17 | Small intestinal stenosis (HP:0012848) | 3.32748511 |
18 | Duodenal stenosis (HP:0100867) | 3.32748511 |
19 | Impulsivity (HP:0100710) | 3.29386990 |
20 | Absent radius (HP:0003974) | 3.25754780 |
21 | Rough bone trabeculation (HP:0100670) | 3.05651101 |
22 | Absent forearm bone (HP:0003953) | 3.03447336 |
23 | Aplasia involving forearm bones (HP:0009822) | 3.03447336 |
24 | Medulloblastoma (HP:0002885) | 2.99299926 |
25 | Abnormality of the labia minora (HP:0012880) | 2.97883727 |
26 | Myelodysplasia (HP:0002863) | 2.91148090 |
27 | Colon cancer (HP:0003003) | 2.88504954 |
28 | Macrocytic anemia (HP:0001972) | 2.88189408 |
29 | Aplastic anemia (HP:0001915) | 2.87943683 |
30 | Horseshoe kidney (HP:0000085) | 2.85922529 |
31 | Pancreatic cysts (HP:0001737) | 2.83799504 |
32 | Abnormal lung lobation (HP:0002101) | 2.77975194 |
33 | Selective tooth agenesis (HP:0001592) | 2.77740527 |
34 | Absent thumb (HP:0009777) | 2.77706392 |
35 | Abnormality of the anterior horn cell (HP:0006802) | 2.73239769 |
36 | Degeneration of anterior horn cells (HP:0002398) | 2.73239769 |
37 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 2.71145387 |
38 | Rhabdomyosarcoma (HP:0002859) | 2.71018252 |
39 | Pallor (HP:0000980) | 2.70581990 |
40 | Abnormality of the duodenum (HP:0002246) | 2.68321114 |
41 | Triphalangeal thumb (HP:0001199) | 2.67709231 |
42 | Facial hemangioma (HP:0000329) | 2.67157311 |
43 | Cleft eyelid (HP:0000625) | 2.63473361 |
44 | Microretrognathia (HP:0000308) | 2.63037449 |
45 | Sloping forehead (HP:0000340) | 2.57339143 |
46 | Abnormality of alanine metabolism (HP:0010916) | 2.57166851 |
47 | Hyperalaninemia (HP:0003348) | 2.57166851 |
48 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.57166851 |
49 | Secondary amenorrhea (HP:0000869) | 2.57044995 |
50 | Bone marrow hypocellularity (HP:0005528) | 2.56463655 |
51 | Molar tooth sign on MRI (HP:0002419) | 2.55909081 |
52 | Abnormality of midbrain morphology (HP:0002418) | 2.55909081 |
53 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.53772651 |
54 | Pancreatic fibrosis (HP:0100732) | 2.53058042 |
55 | Volvulus (HP:0002580) | 2.52296204 |
56 | Supernumerary spleens (HP:0009799) | 2.52213801 |
57 | Pendular nystagmus (HP:0012043) | 2.51217845 |
58 | Acute necrotizing encephalopathy (HP:0006965) | 2.50693378 |
59 | Duplicated collecting system (HP:0000081) | 2.45937826 |
60 | Ectopic kidney (HP:0000086) | 2.45175316 |
61 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 2.44669454 |
62 | Acute encephalopathy (HP:0006846) | 2.43918322 |
63 | Nephroblastoma (Wilms tumor) (HP:0002667) | 2.41826492 |
64 | Cerebral hypomyelination (HP:0006808) | 2.41792446 |
65 | Neoplasm of the pancreas (HP:0002894) | 2.39490427 |
66 | Congenital stationary night blindness (HP:0007642) | 2.38047489 |
67 | Septo-optic dysplasia (HP:0100842) | 2.37374578 |
68 | Tracheoesophageal fistula (HP:0002575) | 2.36472668 |
69 | Premature graying of hair (HP:0002216) | 2.35888411 |
70 | Increased CSF lactate (HP:0002490) | 2.33605840 |
71 | Abnormality of the pons (HP:0007361) | 2.33504985 |
72 | Abnormal trabecular bone morphology (HP:0100671) | 2.32181325 |
73 | Premature ovarian failure (HP:0008209) | 2.29756360 |
74 | Embryonal renal neoplasm (HP:0011794) | 2.25769102 |
75 | Short thumb (HP:0009778) | 2.25614627 |
76 | True hermaphroditism (HP:0010459) | 2.24283293 |
77 | Atresia of the external auditory canal (HP:0000413) | 2.22995348 |
78 | Abnormality of the carotid arteries (HP:0005344) | 2.20149097 |
79 | Hypoplasia of the pons (HP:0012110) | 2.19364532 |
80 | Clubbing of toes (HP:0100760) | 2.19275077 |
81 | Trismus (HP:0000211) | 2.16939849 |
82 | Neoplasm of the adrenal cortex (HP:0100641) | 2.16880907 |
83 | Small hand (HP:0200055) | 2.16855974 |
84 | Progressive macrocephaly (HP:0004481) | 2.16789677 |
85 | Nephronophthisis (HP:0000090) | 2.15266806 |
86 | Cafe-au-lait spot (HP:0000957) | 2.14549637 |
87 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.11637249 |
88 | Ependymoma (HP:0002888) | 2.10951128 |
89 | Abnormal number of incisors (HP:0011064) | 2.10455696 |
90 | Increased nuchal translucency (HP:0010880) | 2.09423969 |
91 | Mitochondrial inheritance (HP:0001427) | 2.08850091 |
92 | 11 pairs of ribs (HP:0000878) | 2.08123839 |
93 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 2.06455087 |
94 | Oligodactyly (HP:0012165) | 2.05883577 |
95 | Abnormality of the renal collecting system (HP:0004742) | 2.05802833 |
96 | Methylmalonic acidemia (HP:0002912) | 2.05469071 |
97 | Ureteral duplication (HP:0000073) | 2.04709526 |
98 | Cellular immunodeficiency (HP:0005374) | 2.03848208 |
99 | Multiple enchondromatosis (HP:0005701) | 2.02859950 |
100 | Agnosia (HP:0010524) | 2.01625950 |
101 | Hypoplasia of the fovea (HP:0007750) | 2.00257320 |
102 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 2.00257320 |
103 | Slender long bone (HP:0003100) | 1.99823470 |
104 | Capillary hemangiomas (HP:0005306) | 1.98721331 |
105 | Intestinal atresia (HP:0011100) | 1.98021117 |
106 | Abnormal spermatogenesis (HP:0008669) | 1.97608305 |
107 | Abnormality of the renal cortex (HP:0011035) | 1.97230377 |
108 | Progressive inability to walk (HP:0002505) | 1.95900608 |
109 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 1.95474427 |
110 | Basal cell carcinoma (HP:0002671) | 1.95181827 |
111 | Astigmatism (HP:0000483) | 1.94623091 |
112 | Increased serum lactate (HP:0002151) | 1.92779549 |
113 | Squamous cell carcinoma (HP:0002860) | 1.91204578 |
114 | Oligodactyly (hands) (HP:0001180) | 1.90900196 |
115 | Increased hepatocellular lipid droplets (HP:0006565) | 1.87692937 |
116 | Neoplasm of striated muscle (HP:0009728) | 1.86707636 |
117 | Overlapping toe (HP:0001845) | 1.83427241 |
118 | Glioma (HP:0009733) | 1.83175556 |
119 | Aplasia/Hypoplasia of the breasts (HP:0010311) | 1.83004539 |
120 | Abnormality of DNA repair (HP:0003254) | 1.82990904 |
121 | Lipid accumulation in hepatocytes (HP:0006561) | 1.82640547 |
122 | Neoplasm of the colon (HP:0100273) | 1.81620685 |
123 | Medial flaring of the eyebrow (HP:0010747) | 1.81321324 |
124 | Absent septum pellucidum (HP:0001331) | 1.81000619 |
125 | Abnormality of the renal medulla (HP:0100957) | 1.80459140 |
126 | Breast aplasia (HP:0100783) | 1.80094072 |
127 | Abnormality of reticulocytes (HP:0004312) | 1.79796115 |
128 | Absent epiphyses (HP:0010577) | 1.79382877 |
129 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 1.79382877 |
130 | Dandy-Walker malformation (HP:0001305) | 1.79353010 |
131 | Aplasia/Hypoplasia of the earlobes (HP:0009906) | 1.78549985 |
132 | Oligohydramnios (HP:0001562) | 1.77872053 |
133 | Pancytopenia (HP:0001876) | 1.77158835 |
134 | Arteriovenous malformation (HP:0100026) | 1.76996401 |
135 | Congenital, generalized hypertrichosis (HP:0004540) | 1.76644172 |
136 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.74791267 |
137 | Abdominal situs inversus (HP:0003363) | 1.74560851 |
138 | Abnormality of abdominal situs (HP:0011620) | 1.74560851 |
139 | Prominent nose (HP:0000448) | 1.73949481 |
140 | Methylmalonic aciduria (HP:0012120) | 1.73729817 |
141 | Irregular epiphyses (HP:0010582) | 1.73718281 |
142 | Neoplasm of the adrenal gland (HP:0100631) | 1.73471510 |
143 | Hepatocellular necrosis (HP:0001404) | 1.72593810 |
144 | Short middle phalanx of the 5th finger (HP:0004220) | 1.71563466 |
145 | Sclerocornea (HP:0000647) | 1.71406234 |
146 | Abnormality of pyrimidine metabolism (HP:0004353) | 1.70967372 |
147 | Optic nerve hypoplasia (HP:0000609) | 1.69396837 |
148 | Preaxial hand polydactyly (HP:0001177) | 1.69198312 |
149 | Abnormality of the fovea (HP:0000493) | 1.68297782 |
150 | Abnormality of serum amino acid levels (HP:0003112) | 1.67758380 |
151 | Attenuation of retinal blood vessels (HP:0007843) | 1.67110325 |
152 | Type II lissencephaly (HP:0007260) | 1.65501035 |
153 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.64077429 |
154 | Lissencephaly (HP:0001339) | 1.62058898 |
155 | Cerebral edema (HP:0002181) | 1.61861363 |
156 | Abnormality of the septum pellucidum (HP:0007375) | 1.61490626 |
157 | Hypoplastic pelvis (HP:0008839) | 1.58555760 |
158 | Hepatic necrosis (HP:0002605) | 1.57753038 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BUB1 | 5.58283805 |
2 | WEE1 | 4.83758846 |
3 | CDC7 | 4.12931927 |
4 | EIF2AK1 | 3.54156861 |
5 | NEK2 | 3.27450239 |
6 | TTK | 2.87262190 |
7 | FRK | 2.83863354 |
8 | BRSK2 | 2.76179211 |
9 | SRPK1 | 2.71948096 |
10 | PLK4 | 2.54921573 |
11 | NEK1 | 2.50350191 |
12 | BMPR1B | 2.49966868 |
13 | TLK1 | 2.42929242 |
14 | PLK1 | 2.41675017 |
15 | NME2 | 2.38306459 |
16 | TRIM28 | 2.37471524 |
17 | VRK2 | 2.36196222 |
18 | NUAK1 | 2.31658295 |
19 | ACVR1B | 2.28592063 |
20 | AURKB | 2.02884469 |
21 | BRSK1 | 2.00282278 |
22 | CCNB1 | 1.91889265 |
23 | TESK2 | 1.88976467 |
24 | MST4 | 1.85243958 |
25 | VRK1 | 1.82576733 |
26 | STK16 | 1.80456751 |
27 | TAF1 | 1.77662469 |
28 | MKNK1 | 1.72817362 |
29 | WNK3 | 1.71847707 |
30 | DYRK3 | 1.69188123 |
31 | CHEK2 | 1.66774813 |
32 | MKNK2 | 1.66581050 |
33 | CDK7 | 1.64308521 |
34 | EIF2AK3 | 1.61330360 |
35 | PLK3 | 1.59264738 |
36 | AURKA | 1.50136602 |
37 | ATR | 1.48416800 |
38 | RPS6KA4 | 1.47505747 |
39 | MAP3K8 | 1.34263326 |
40 | STK4 | 1.31552815 |
41 | MAP4K2 | 1.26811301 |
42 | STK10 | 1.22398883 |
43 | CDK4 | 1.21915784 |
44 | CHEK1 | 1.19786421 |
45 | PLK2 | 1.17902623 |
46 | MELK | 1.17149595 |
47 | GRK1 | 1.15674623 |
48 | PBK | 1.13588280 |
49 | ADRBK2 | 1.09620357 |
50 | TNIK | 1.04795184 |
51 | WNK4 | 1.03758598 |
52 | CDK8 | 1.01405531 |
53 | EPHA2 | 0.97243902 |
54 | EIF2AK2 | 0.96913467 |
55 | TSSK6 | 0.96255708 |
56 | ZAK | 0.93604134 |
57 | RPS6KB2 | 0.92416960 |
58 | CDK12 | 0.88634732 |
59 | ERBB3 | 0.88138648 |
60 | BRAF | 0.88048656 |
61 | ATM | 0.86559767 |
62 | PAK4 | 0.84336255 |
63 | PDK2 | 0.83012059 |
64 | CDK2 | 0.82447308 |
65 | BCR | 0.81248093 |
66 | STK39 | 0.80660745 |
67 | LATS2 | 0.78821435 |
68 | STK3 | 0.77650863 |
69 | STK38L | 0.76862716 |
70 | INSRR | 0.76166317 |
71 | PIM1 | 0.75579931 |
72 | CLK1 | 0.73075651 |
73 | PASK | 0.72866368 |
74 | CDK1 | 0.71324660 |
75 | PAK1 | 0.67047898 |
76 | CSNK2A1 | 0.66397328 |
77 | CDK6 | 0.66202186 |
78 | MAP3K4 | 0.64739802 |
79 | CSNK1G1 | 0.60669732 |
80 | MAPK13 | 0.59280017 |
81 | RPS6KA5 | 0.59264727 |
82 | OXSR1 | 0.59016362 |
83 | CSNK2A2 | 0.55814346 |
84 | MAP3K11 | 0.53321806 |
85 | ERBB4 | 0.53282352 |
86 | CSNK1G3 | 0.50777436 |
87 | PINK1 | 0.48268692 |
88 | DYRK2 | 0.46379049 |
89 | NEK9 | 0.46066892 |
90 | KDR | 0.46053646 |
91 | TESK1 | 0.45258427 |
92 | PRKCI | 0.45023497 |
93 | ALK | 0.44853869 |
94 | CSNK1G2 | 0.43215272 |
95 | MAPKAPK5 | 0.42725456 |
96 | CSNK1A1L | 0.42029385 |
97 | ADRBK1 | 0.39907205 |
98 | FGFR2 | 0.39245549 |
99 | NME1 | 0.38011564 |
100 | BRD4 | 0.37178504 |
101 | LATS1 | 0.36842979 |
102 | TGFBR1 | 0.36730520 |
103 | ABL2 | 0.36084115 |
104 | PRKCG | 0.35888980 |
105 | MAP3K6 | 0.34608648 |
106 | MAP3K10 | 0.34086909 |
107 | PIM2 | 0.33630627 |
108 | MARK3 | 0.33514272 |
109 | TAOK3 | 0.33252080 |
110 | AKT3 | 0.33045549 |
111 | CDK3 | 0.31832845 |
112 | PNCK | 0.29637435 |
113 | NLK | 0.28695795 |
114 | IRAK3 | 0.28350599 |
115 | EEF2K | 0.27584342 |
116 | SCYL2 | 0.27049664 |
117 | LRRK2 | 0.26550066 |
118 | PRKDC | 0.25962754 |
119 | MAP4K1 | 0.25052402 |
120 | CDK11A | 0.24282047 |
121 | AKT2 | 0.24104317 |
122 | PRKCE | 0.23100264 |
123 | CDK15 | 0.20427663 |
124 | CDK9 | 0.20063593 |
125 | PAK3 | 0.19188403 |
126 | CSNK1E | 0.18552107 |
127 | CSNK1A1 | 0.18486764 |
128 | CSNK1D | 0.18338446 |
129 | PKN1 | 0.18235791 |
130 | MAPK14 | 0.18149425 |
131 | CDK18 | 0.17975452 |
132 | LIMK1 | 0.16333045 |
133 | MAPK11 | 0.16227634 |
134 | CDK14 | 0.15382726 |
135 | AKT1 | 0.15334517 |
136 | MAPKAPK3 | 0.14538067 |
137 | MAPKAPK2 | 0.12379939 |
138 | FLT3 | 0.11613603 |
139 | RPS6KA1 | 0.11255717 |
140 | IRAK4 | 0.11241969 |
141 | MAP3K5 | 0.10596050 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DNA replication_Homo sapiens_hsa03030 | 5.09079931 |
2 | Mismatch repair_Homo sapiens_hsa03430 | 4.24052257 |
3 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.71459572 |
4 | Ribosome_Homo sapiens_hsa03010 | 3.47366790 |
5 | Homologous recombination_Homo sapiens_hsa03440 | 3.43646697 |
6 | RNA polymerase_Homo sapiens_hsa03020 | 3.43393991 |
7 | Spliceosome_Homo sapiens_hsa03040 | 3.33781405 |
8 | Cell cycle_Homo sapiens_hsa04110 | 3.28629348 |
9 | RNA transport_Homo sapiens_hsa03013 | 3.17497517 |
10 | Base excision repair_Homo sapiens_hsa03410 | 3.09546561 |
11 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.97552166 |
12 | Proteasome_Homo sapiens_hsa03050 | 2.97440789 |
13 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.73413538 |
14 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.60188991 |
15 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.40746636 |
16 | Basal transcription factors_Homo sapiens_hsa03022 | 2.32044327 |
17 | RNA degradation_Homo sapiens_hsa03018 | 1.93615324 |
18 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.87957530 |
19 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.84454120 |
20 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.83591011 |
21 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.81451724 |
22 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.41529562 |
23 | Phototransduction_Homo sapiens_hsa04744 | 1.41262510 |
24 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.40937038 |
25 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.40913358 |
26 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.39701250 |
27 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.38112973 |
28 | Purine metabolism_Homo sapiens_hsa00230 | 1.37854257 |
29 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.24722960 |
30 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.24380121 |
31 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.20746482 |
32 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.13071934 |
33 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.08767052 |
34 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.01438100 |
35 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.00683953 |
36 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.99137237 |
37 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.94783894 |
38 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.93455757 |
39 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.92285317 |
40 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.92046000 |
41 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.89553293 |
42 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.89297717 |
43 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.89223325 |
44 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.86995649 |
45 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.86326663 |
46 | Alzheimers disease_Homo sapiens_hsa05010 | 0.85568518 |
47 | Sulfur relay system_Homo sapiens_hsa04122 | 0.83617735 |
48 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.79932268 |
49 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.76219578 |
50 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.76202147 |
51 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.75363513 |
52 | Protein export_Homo sapiens_hsa03060 | 0.74125366 |
53 | HTLV-I infection_Homo sapiens_hsa05166 | 0.73719857 |
54 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.69111990 |
55 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.68668365 |
56 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.68107175 |
57 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.68002662 |
58 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.67249789 |
59 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.66194582 |
60 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.63245478 |
61 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.61911463 |
62 | Huntingtons disease_Homo sapiens_hsa05016 | 0.61421322 |
63 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.59257128 |
64 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.58108608 |
65 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.56727873 |
66 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.56443762 |
67 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.55696369 |
68 | Thyroid cancer_Homo sapiens_hsa05216 | 0.53322589 |
69 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.52268518 |
70 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.49933321 |
71 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.49665699 |
72 | Peroxisome_Homo sapiens_hsa04146 | 0.48722395 |
73 | Alcoholism_Homo sapiens_hsa05034 | 0.47105497 |
74 | Olfactory transduction_Homo sapiens_hsa04740 | 0.47048764 |
75 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.45955469 |
76 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.43740008 |
77 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.43031662 |
78 | Lysine degradation_Homo sapiens_hsa00310 | 0.42792266 |
79 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.39442167 |
80 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.39055884 |
81 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.38458619 |
82 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.37082362 |
83 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.36774356 |
84 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.36082010 |
85 | Apoptosis_Homo sapiens_hsa04210 | 0.35578636 |
86 | Bladder cancer_Homo sapiens_hsa05219 | 0.35248281 |
87 | Hepatitis B_Homo sapiens_hsa05161 | 0.35047911 |
88 | Nicotine addiction_Homo sapiens_hsa05033 | 0.35008389 |
89 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.34956487 |
90 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.34869544 |
91 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.34192670 |
92 | Parkinsons disease_Homo sapiens_hsa05012 | 0.33267312 |
93 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.32508174 |
94 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.30132201 |
95 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.28735177 |
96 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.28235773 |
97 | Legionellosis_Homo sapiens_hsa05134 | 0.27697422 |
98 | Colorectal cancer_Homo sapiens_hsa05210 | 0.27473770 |
99 | Retinol metabolism_Homo sapiens_hsa00830 | 0.26746950 |
100 | Taste transduction_Homo sapiens_hsa04742 | 0.26544953 |
101 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.25668581 |
102 | Carbon metabolism_Homo sapiens_hsa01200 | 0.25266896 |
103 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.23569979 |
104 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.22464822 |
105 | Shigellosis_Homo sapiens_hsa05131 | 0.21521436 |
106 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.20837168 |
107 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.20797468 |
108 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.20544941 |
109 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.19645192 |
110 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.19378065 |
111 | Metabolic pathways_Homo sapiens_hsa01100 | 0.19231300 |
112 | Pathways in cancer_Homo sapiens_hsa05200 | 0.18463124 |
113 | Measles_Homo sapiens_hsa05162 | 0.18041180 |
114 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.17720337 |
115 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.17589875 |
116 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.17122058 |
117 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.16826314 |
118 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.16176683 |
119 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.15777112 |
120 | Prostate cancer_Homo sapiens_hsa05215 | 0.15759049 |
121 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.15103189 |
122 | Influenza A_Homo sapiens_hsa05164 | 0.14078679 |
123 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.13484110 |
124 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.13190452 |
125 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.12383969 |
126 | Melanoma_Homo sapiens_hsa05218 | 0.11365477 |
127 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.09995114 |
128 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.09831310 |
129 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.09269079 |
130 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.07837452 |
131 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.07322116 |
132 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.07135241 |
133 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.06187710 |
134 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.06089143 |
135 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.05246189 |
136 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.05146921 |
137 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.04929035 |
138 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.04262538 |
139 | Galactose metabolism_Homo sapiens_hsa00052 | 0.04211617 |
140 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.02467031 |