SKIDA1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1rhodopsin mediated signaling pathway (GO:0016056)4.72232596
2regulation of rhodopsin mediated signaling pathway (GO:0022400)4.65717108
3somite development (GO:0061053)4.25888434
4behavioral response to nicotine (GO:0035095)3.98634796
5spinal cord development (GO:0021510)3.93630637
6retinal cone cell development (GO:0046549)3.91261756
7replication fork processing (GO:0031297)3.67839534
8photoreceptor cell maintenance (GO:0045494)3.62274357
9axonal fasciculation (GO:0007413)3.55861521
10photoreceptor cell development (GO:0042461)3.47247998
11paraxial mesoderm development (GO:0048339)3.45549019
12cell migration in hindbrain (GO:0021535)3.38281641
13positive regulation of dendritic spine morphogenesis (GO:0061003)3.38025068
14DNA double-strand break processing (GO:0000729)3.37795220
15chromatin remodeling at centromere (GO:0031055)3.37444395
16intraciliary transport (GO:0042073)3.37054255
17retinal rod cell development (GO:0046548)3.35862179
18nucleobase catabolic process (GO:0046113)3.33625837
19olfactory bulb development (GO:0021772)3.31627553
20presynaptic membrane assembly (GO:0097105)3.30180629
21lateral sprouting from an epithelium (GO:0060601)3.29332661
22neuron recognition (GO:0008038)3.25906320
23negative regulation of catenin import into nucleus (GO:0035414)3.25628670
24resolution of meiotic recombination intermediates (GO:0000712)3.25460029
25pyrimidine nucleobase catabolic process (GO:0006208)3.25122697
26peptidyl-arginine omega-N-methylation (GO:0035247)3.24535378
27eye photoreceptor cell development (GO:0042462)3.24139564
28limb development (GO:0060173)3.15774465
29appendage development (GO:0048736)3.15774465
30layer formation in cerebral cortex (GO:0021819)3.10981582
31negative regulation of translation, ncRNA-mediated (GO:0040033)3.09230665
32regulation of translation, ncRNA-mediated (GO:0045974)3.09230665
33negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.09230665
34response to pheromone (GO:0019236)3.08702337
35protein polyglutamylation (GO:0018095)3.08396011
36central nervous system projection neuron axonogenesis (GO:0021952)3.07912837
37presynaptic membrane organization (GO:0097090)3.07512584
38protein localization to synapse (GO:0035418)3.04160657
39peptidyl-arginine N-methylation (GO:0035246)3.02400531
40peptidyl-arginine methylation (GO:0018216)3.02400531
41positive regulation of gastrulation (GO:2000543)3.01526550
42negative regulation of transcription regulatory region DNA binding (GO:2000678)3.00595696
43detection of light stimulus involved in sensory perception (GO:0050962)2.97777995
44detection of light stimulus involved in visual perception (GO:0050908)2.97777995
45neural tube formation (GO:0001841)2.97609479
46planar cell polarity pathway involved in neural tube closure (GO:0090179)2.96335923
47neuronal stem cell maintenance (GO:0097150)2.94290016
48substrate-independent telencephalic tangential migration (GO:0021826)2.93009868
49substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.93009868
50regulation of non-canonical Wnt signaling pathway (GO:2000050)2.92744402
51CENP-A containing nucleosome assembly (GO:0034080)2.92322616
52somite rostral/caudal axis specification (GO:0032525)2.91613333
53cerebral cortex radially oriented cell migration (GO:0021799)2.91071642
54neuron fate determination (GO:0048664)2.90384547
55negative chemotaxis (GO:0050919)2.89006072
56proximal/distal pattern formation (GO:0009954)2.88494439
57outer ear morphogenesis (GO:0042473)2.87265403
58negative regulation of astrocyte differentiation (GO:0048712)2.84282434
59maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.82789741
60histone arginine methylation (GO:0034969)2.82504455
61kinetochore assembly (GO:0051382)2.81090574
62hindbrain development (GO:0030902)2.80987622
63kinetochore organization (GO:0051383)2.80829393
64nonmotile primary cilium assembly (GO:0035058)2.80374043
65regulation of mesoderm development (GO:2000380)2.80047153
66regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.79094287
67regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.78309206
68dendritic spine morphogenesis (GO:0060997)2.77296511
69otic vesicle formation (GO:0030916)2.74834986
70phototransduction, visible light (GO:0007603)2.72107349
71protein-DNA complex disassembly (GO:0032986)2.71327818
72nucleosome disassembly (GO:0006337)2.71327818
73positive regulation of synapse maturation (GO:0090129)2.71181328
74hippocampus development (GO:0021766)2.70290620
75postsynaptic membrane organization (GO:0001941)2.69591712
76histone exchange (GO:0043486)2.69530472
77atrial cardiac muscle cell action potential (GO:0086014)2.69396491
78dorsal/ventral axis specification (GO:0009950)2.68596016
79pre-miRNA processing (GO:0031054)2.67774787
80detection of visible light (GO:0009584)2.67175878
81phototransduction (GO:0007602)2.66963477
82cell proliferation in forebrain (GO:0021846)2.66741277
83epithelial cilium movement (GO:0003351)2.65115589
84regulation of timing of cell differentiation (GO:0048505)2.65109225
85regulation of gene silencing by RNA (GO:0060966)2.65000037
86regulation of posttranscriptional gene silencing (GO:0060147)2.65000037
87regulation of gene silencing by miRNA (GO:0060964)2.65000037
88transmission of nerve impulse (GO:0019226)2.64877398
89protein localization to cilium (GO:0061512)2.62684063
90regulation of development, heterochronic (GO:0040034)2.62478184
91epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.61862512
92cornea development in camera-type eye (GO:0061303)2.61799388
93body morphogenesis (GO:0010171)2.61735382
94dorsal/ventral pattern formation (GO:0009953)2.61260134
95innervation (GO:0060384)2.61057851
96cranial nerve morphogenesis (GO:0021602)2.60403886
97neuron cell-cell adhesion (GO:0007158)2.60109882
98detection of light stimulus (GO:0009583)2.57007371
99artery development (GO:0060840)2.56953692
100regulation of collateral sprouting (GO:0048670)2.56915956
101endocardial cushion morphogenesis (GO:0003203)2.56449926
102notochord development (GO:0030903)2.56277464
103negative regulation of axon guidance (GO:1902668)2.55849927
104retinal ganglion cell axon guidance (GO:0031290)2.54631864
105kidney morphogenesis (GO:0060993)2.54283256
106head development (GO:0060322)2.53947086
107hindlimb morphogenesis (GO:0035137)2.53385519
108synaptic vesicle docking involved in exocytosis (GO:0016081)2.50565994
109centriole replication (GO:0007099)2.50378084
110negative regulation of oligodendrocyte differentiation (GO:0048715)2.49739825
111positive regulation of synapse assembly (GO:0051965)2.49202620
112negative regulation of DNA-dependent DNA replication (GO:2000104)2.48553703
113negative regulation of organelle assembly (GO:1902116)2.48115689
114establishment of tissue polarity (GO:0007164)2.47340562
115establishment of planar polarity (GO:0001736)2.47340562
116glial cell proliferation (GO:0014009)2.46177600
117behavioral response to ethanol (GO:0048149)2.46010852
118cilium organization (GO:0044782)2.45617447
119pituitary gland development (GO:0021983)2.45311885
120recombinational repair (GO:0000725)2.44523375
121cilium assembly (GO:0042384)2.42991720
122DNA replication-independent nucleosome assembly (GO:0006336)2.42926969
123DNA replication-independent nucleosome organization (GO:0034724)2.42926969
124axon extension involved in axon guidance (GO:0048846)2.42839425
125neuron projection extension involved in neuron projection guidance (GO:1902284)2.42839425
126mesenchyme morphogenesis (GO:0072132)2.42797881
127double-strand break repair via homologous recombination (GO:0000724)2.42756525
128forebrain neuron differentiation (GO:0021879)2.42697008
129retina layer formation (GO:0010842)2.42283703
130neuronal ion channel clustering (GO:0045161)2.41872001
131sympathetic nervous system development (GO:0048485)2.40912546
132regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.39965910
133forelimb morphogenesis (GO:0035136)2.39329874
134hippo signaling (GO:0035329)2.38460723
135DNA damage response, detection of DNA damage (GO:0042769)2.38131691
136embryonic foregut morphogenesis (GO:0048617)2.37201574
137negative regulation of axon extension involved in axon guidance (GO:0048843)2.37167979
138embryonic body morphogenesis (GO:0010172)2.36680978
139sensory perception of light stimulus (GO:0050953)2.36671495
140visual perception (GO:0007601)2.36234063
141synaptic vesicle endocytosis (GO:0048488)2.35922671
142mRNA splice site selection (GO:0006376)2.35687295
143cellular response to light stimulus (GO:0071482)2.35154182
144thalamus development (GO:0021794)2.34907044
145regulation of nuclear cell cycle DNA replication (GO:0033262)2.34763342
146regulation of DNA endoreduplication (GO:0032875)2.34502582
147regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.33974500
148protein complex biogenesis (GO:0070271)2.33685941
149ephrin receptor signaling pathway (GO:0048013)2.33544460
150embryonic forelimb morphogenesis (GO:0035115)2.33533622
151myelin assembly (GO:0032288)2.32888217
152smoothened signaling pathway (GO:0007224)2.32887056
153convergent extension (GO:0060026)2.32861343
154negative regulation of glial cell differentiation (GO:0045686)2.32731241
155regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.32683379
156DNA ligation (GO:0006266)2.31853078
157calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.31703174
158GMP metabolic process (GO:0046037)2.31271585
159retina development in camera-type eye (GO:0060041)2.30827296
160neuron migration (GO:0001764)2.30810449
161regulation of telomere maintenance (GO:0032204)2.29672750
162embryonic hindlimb morphogenesis (GO:0035116)2.29530830
163DNA replication checkpoint (GO:0000076)2.29388323
164central nervous system neuron axonogenesis (GO:0021955)2.28896536
165cochlea morphogenesis (GO:0090103)2.28548415
166limb bud formation (GO:0060174)2.28382466
167dopaminergic neuron differentiation (GO:0071542)2.28156237
168cilium morphogenesis (GO:0060271)2.27842804
169mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.27680038
170mitochondrial respiratory chain complex I assembly (GO:0032981)2.27680038
171NADH dehydrogenase complex assembly (GO:0010257)2.27680038
172protein K6-linked ubiquitination (GO:0085020)2.27372978
173microtubule depolymerization (GO:0007019)2.25014918
174inner ear receptor cell development (GO:0060119)2.23379921

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse4.49213992
2EZH2_22144423_ChIP-Seq_EOC_Human4.03690769
3GLI1_17442700_ChIP-ChIP_MESCs_Mouse3.43199262
4EZH2_27304074_Chip-Seq_ESCs_Mouse3.06639757
5TP63_19390658_ChIP-ChIP_HaCaT_Human2.94666247
6JARID2_20064375_ChIP-Seq_MESCs_Mouse2.78488366
7EED_16625203_ChIP-ChIP_MESCs_Mouse2.68860236
8CBX2_27304074_Chip-Seq_ESCs_Mouse2.55091068
9RNF2_18974828_ChIP-Seq_MESCs_Mouse2.52215198
10EZH2_18974828_ChIP-Seq_MESCs_Mouse2.52215198
11ZFP57_27257070_Chip-Seq_ESCs_Mouse2.48893997
12RBPJ_22232070_ChIP-Seq_NCS_Mouse2.48556251
13JARID2_20075857_ChIP-Seq_MESCs_Mouse2.48321133
14PHC1_16625203_ChIP-ChIP_MESCs_Mouse2.42125430
15ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.34212241
16TAF15_26573619_Chip-Seq_HEK293_Human2.33969162
17CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.31817896
18RNF2_27304074_Chip-Seq_ESCs_Mouse2.31576427
19SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.30465222
20MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.29031864
21ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.26011737
22SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.23193791
23GBX2_23144817_ChIP-Seq_PC3_Human2.20635209
24BMI1_23680149_ChIP-Seq_NPCS_Mouse2.19286711
25POU3F2_20337985_ChIP-ChIP_501MEL_Human2.18223167
26SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.18092606
27RNF2_16625203_ChIP-ChIP_MESCs_Mouse2.16051599
28POU5F1_16153702_ChIP-ChIP_HESCs_Human2.15924410
29EZH2_27294783_Chip-Seq_ESCs_Mouse2.03558950
30GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.99995864
31EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.98173731
32SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.94307509
33RING1B_27294783_Chip-Seq_NPCs_Mouse1.93899257
34NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.89016068
35SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.85653250
36RNF2_27304074_Chip-Seq_NSC_Mouse1.80865842
37ZFP281_18757296_ChIP-ChIP_E14_Mouse1.79223252
38SUZ12_27294783_Chip-Seq_ESCs_Mouse1.78388176
39E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.76292563
40TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.73448392
41HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.69682828
42RING1B_27294783_Chip-Seq_ESCs_Mouse1.67467611
43TP53_20018659_ChIP-ChIP_R1E_Mouse1.66963777
44IRF1_19129219_ChIP-ChIP_H3396_Human1.66635696
45SALL1_21062744_ChIP-ChIP_HESCs_Human1.64257973
46HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.63683082
47SOX2_16153702_ChIP-ChIP_HESCs_Human1.59030269
48MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.57225803
49PIAS1_25552417_ChIP-Seq_VCAP_Human1.54791487
50MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.53722071
51MYC_18940864_ChIP-ChIP_HL60_Human1.52277527
52SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.52025636
53AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.50953953
54IGF1R_20145208_ChIP-Seq_DFB_Human1.49795101
55KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.47171659
56MTF2_20144788_ChIP-Seq_MESCs_Mouse1.45635409
57OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.42580778
58SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.41389757
59UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.39840071
60EST1_17652178_ChIP-ChIP_JURKAT_Human1.39520806
61FLI1_27457419_Chip-Seq_LIVER_Mouse1.38585090
62WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.37600179
63REST_21632747_ChIP-Seq_MESCs_Mouse1.36339903
64ISL1_27105846_Chip-Seq_CPCs_Mouse1.34923825
65FOXM1_23109430_ChIP-Seq_U2OS_Human1.34769171
66GABP_17652178_ChIP-ChIP_JURKAT_Human1.33456344
67FUS_26573619_Chip-Seq_HEK293_Human1.32902989
68ZFP281_27345836_Chip-Seq_ESCs_Mouse1.31658895
69VDR_22108803_ChIP-Seq_LS180_Human1.31608197
70SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.30842626
71BCAT_22108803_ChIP-Seq_LS180_Human1.29883877
72KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.29568698
73EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.29210425
74SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.26694945
75ER_23166858_ChIP-Seq_MCF-7_Human1.26561366
76E2F7_22180533_ChIP-Seq_HELA_Human1.26125984
77AR_21572438_ChIP-Seq_LNCaP_Human1.25165227
78AR_25329375_ChIP-Seq_VCAP_Human1.24399137
79SOX2_18555785_ChIP-Seq_MESCs_Mouse1.23820374
80OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.22648733
81REST_18959480_ChIP-ChIP_MESCs_Mouse1.22039302
82CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.21904297
83PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.21837761
84ELK1_19687146_ChIP-ChIP_HELA_Human1.21462620
85KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.20937446
86KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.20304538
87EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.18898506
88DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.18721910
89SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.18457319
90RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.18250650
91STAT3_23295773_ChIP-Seq_U87_Human1.18028445
92GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.16901371
93CTBP1_25329375_ChIP-Seq_LNCAP_Human1.16476390
94IKZF1_21737484_ChIP-ChIP_HCT116_Human1.15474895
95IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.15335668
96CBP_20019798_ChIP-Seq_JUKART_Human1.15335668
97CTBP2_25329375_ChIP-Seq_LNCAP_Human1.14944641
98NR3C1_21868756_ChIP-Seq_MCF10A_Human1.13644905
99CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.12565708
100E2F4_17652178_ChIP-ChIP_JURKAT_Human1.11161862
101SOX9_26525672_Chip-Seq_HEART_Mouse1.09474586
102NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.09087456
103RUNX2_22187159_ChIP-Seq_PCA_Human1.08303079
104SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.06391385
105TCF4_23295773_ChIP-Seq_U87_Human1.06352375
106PCGF2_27294783_Chip-Seq_ESCs_Mouse1.06206356
107KLF5_20875108_ChIP-Seq_MESCs_Mouse1.06189879
108TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.06052116
109SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.05977511
110ERG_21242973_ChIP-ChIP_JURKAT_Human1.05791370
111TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04850515
112FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.04302247
113AR_19668381_ChIP-Seq_PC3_Human1.03915500
114TCF4_22108803_ChIP-Seq_LS180_Human1.03769517
115STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.03723359
116NANOG_21062744_ChIP-ChIP_HESCs_Human1.02264696
117NANOG_18555785_Chip-Seq_ESCs_Mouse1.02188038
118YAP1_20516196_ChIP-Seq_MESCs_Mouse1.01674790
119TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.01498829
120TOP2B_26459242_ChIP-Seq_MCF-7_Human1.00089698
121P300_19829295_ChIP-Seq_ESCs_Human1.00004510
122EWS_26573619_Chip-Seq_HEK293_Human0.99970764
123PCGF2_27294783_Chip-Seq_NPCs_Mouse0.98771654
124RARB_27405468_Chip-Seq_BRAIN_Mouse0.98662805
125TBX3_20139965_ChIP-Seq_ESCs_Mouse0.97947806
126TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.97686271
127TBX3_20139965_ChIP-Seq_MESCs_Mouse0.97407108
128EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.95903959
129POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.95481405
130CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.94546174
131FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.94034816
132SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.93648784
133TCF3_18692474_ChIP-Seq_MESCs_Mouse0.92984045
134NANOG_16153702_ChIP-ChIP_HESCs_Human0.92458100
135YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.91566488
136WT1_25993318_ChIP-Seq_PODOCYTE_Human0.91518677
137NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.91363811
138DROSHA_22980978_ChIP-Seq_HELA_Human0.89408790
139P53_22127205_ChIP-Seq_FIBROBLAST_Human0.89217304
140TCF3_18347094_ChIP-ChIP_MESCs_Mouse0.89010504
141TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.88584000
142POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.88584000
143POU3F1_26484290_ChIP-Seq_ESCss_Mouse0.87678043
144SOX3_22085726_ChIP-Seq_NPCs_Mouse0.87115167
145ZNF274_21170338_ChIP-Seq_K562_Hela0.86931159
146SMAD4_21799915_ChIP-Seq_A2780_Human0.86464100
147SMAD3_21741376_ChIP-Seq_EPCs_Human0.86316515

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005551_abnormal_eye_electrophysiolog2.99429287
2MP0003011_delayed_dark_adaptation2.84322288
3MP0010030_abnormal_orbit_morphology2.75595093
4MP0003122_maternal_imprinting2.70977107
5MP0003880_abnormal_central_pattern2.70733179
6MP0006292_abnormal_olfactory_placode2.51452182
7MP0005253_abnormal_eye_physiology2.48851228
8MP0005423_abnormal_somatic_nervous2.40350030
9MP0008789_abnormal_olfactory_epithelium2.38794333
10MP0002653_abnormal_ependyma_morphology2.37512883
11MP0006072_abnormal_retinal_apoptosis2.31694908
12MP0000778_abnormal_nervous_system2.31044848
13MP0002938_white_spotting2.24505634
14MP0005499_abnormal_olfactory_system2.22283098
15MP0005394_taste/olfaction_phenotype2.22283098
16MP0000049_abnormal_middle_ear2.12699244
17MP0003121_genomic_imprinting2.10692497
18MP0002102_abnormal_ear_morphology2.07814357
19MP0003385_abnormal_body_wall1.91678566
20MP0000566_synostosis1.90876079
21MP0008877_abnormal_DNA_methylation1.83785650
22MP0000537_abnormal_urethra_morphology1.81364010
23MP0004859_abnormal_synaptic_plasticity1.80061541
24MP0005248_abnormal_Harderian_gland1.74193153
25MP0003136_yellow_coat_color1.72614989
26MP0003119_abnormal_digestive_system1.70629025
27MP0003942_abnormal_urinary_system1.65563161
28MP0003123_paternal_imprinting1.62868526
29MP0005391_vision/eye_phenotype1.62377454
30MP0009053_abnormal_anal_canal1.60018805
31MP0003315_abnormal_perineum_morphology1.57559917
32MP0002249_abnormal_larynx_morphology1.57107988
33MP0001485_abnormal_pinna_reflex1.55063513
34MP0005195_abnormal_posterior_eye1.54820413
35MP0002751_abnormal_autonomic_nervous1.54064725
36MP0000631_abnormal_neuroendocrine_gland1.53020042
37MP0008058_abnormal_DNA_repair1.50050465
38MP0003890_abnormal_embryonic-extraembry1.48936276
39MP0006276_abnormal_autonomic_nervous1.46775402
40MP0003861_abnormal_nervous_system1.45833018
41MP0005187_abnormal_penis_morphology1.45566559
42MP0003938_abnormal_ear_development1.45090105
43MP0003937_abnormal_limbs/digits/tail_de1.44499538
44MP0003787_abnormal_imprinting1.42352846
45MP0003755_abnormal_palate_morphology1.39747675
46MP0009250_abnormal_appendicular_skeleto1.37442972
47MP0002638_abnormal_pupillary_reflex1.36534710
48MP0002234_abnormal_pharynx_morphology1.35557568
49MP0002233_abnormal_nose_morphology1.34607597
50MP0002184_abnormal_innervation1.34442418
51MP0002752_abnormal_somatic_nervous1.34190431
52MP0002736_abnormal_nociception_after1.32622261
53MP0001324_abnormal_eye_pigmentation1.31990914
54MP0002282_abnormal_trachea_morphology1.30984215
55MP0001293_anophthalmia1.29472803
56MP0004885_abnormal_endolymph1.29334404
57MP0001984_abnormal_olfaction1.28650610
58MP0002882_abnormal_neuron_morphology1.25906123
59MP0001286_abnormal_eye_development1.25689890
60MP0003935_abnormal_craniofacial_develop1.24290766
61MP0002063_abnormal_learning/memory/cond1.23616032
62MP0000534_abnormal_ureter_morphology1.22531098
63MP0002116_abnormal_craniofacial_bone1.19998481
64MP0010094_abnormal_chromosome_stability1.17705957
65MP0002697_abnormal_eye_size1.13696173
66MP0002152_abnormal_brain_morphology1.12772568
67MP0003635_abnormal_synaptic_transmissio1.10722269
68MP0009697_abnormal_copulation1.10656687
69MP0003115_abnormal_respiratory_system1.10506047
70MP0000955_abnormal_spinal_cord1.10448001
71MP0002932_abnormal_joint_morphology1.09536612
72MP0009745_abnormal_behavioral_response1.07540737
73MP0003950_abnormal_plasma_membrane1.07074525
74MP0000428_abnormal_craniofacial_morphol1.04318654
75MP0000516_abnormal_urinary_system1.03156719
76MP0005367_renal/urinary_system_phenotyp1.03156719
77MP0004142_abnormal_muscle_tone1.02605186
78MP0005377_hearing/vestibular/ear_phenot1.02536283
79MP0003878_abnormal_ear_physiology1.02536283
80MP0002272_abnormal_nervous_system1.01395145
81MP0004270_analgesia0.99675393
82MP0002572_abnormal_emotion/affect_behav0.98634226
83MP0000026_abnormal_inner_ear0.98042152
84MP0002081_perinatal_lethality0.97721932
85MP0000569_abnormal_digit_pigmentation0.97082434
86MP0002111_abnormal_tail_morphology0.96845502
87MP0001346_abnormal_lacrimal_gland0.96646714
88MP0000647_abnormal_sebaceous_gland0.95338480
89MP0005646_abnormal_pituitary_gland0.95038420
90MP0009046_muscle_twitch0.93265410
91MP0001968_abnormal_touch/_nociception0.91300972
92MP0001486_abnormal_startle_reflex0.91272504
93MP0002085_abnormal_embryonic_tissue0.91171189
94MP0002734_abnormal_mechanical_nocicepti0.91060809
95MP0002114_abnormal_axial_skeleton0.90966537
96MP0002177_abnormal_outer_ear0.89235189
97MP0004811_abnormal_neuron_physiology0.87368268
98MP0002557_abnormal_social/conspecific_i0.87340271
99MP0002092_abnormal_eye_morphology0.87180991
100MP0002735_abnormal_chemical_nociception0.87100445
101MP0001963_abnormal_hearing_physiology0.87092303
102MP0003137_abnormal_impulse_conducting0.87027816
103MP0003693_abnormal_embryo_hatching0.85904070
104MP0003283_abnormal_digestive_organ0.84960720
105MP0005503_abnormal_tendon_morphology0.84659066
106MP0002084_abnormal_developmental_patter0.82364183
107MP0004233_abnormal_muscle_weight0.82265984
108MP0002837_dystrophic_cardiac_calcinosis0.82254033
109MP0001177_atelectasis0.79867025
110MP0005084_abnormal_gallbladder_morpholo0.79820207
111MP0002210_abnormal_sex_determination0.79296073
112MP0002109_abnormal_limb_morphology0.79047284
113MP0002067_abnormal_sensory_capabilities0.78192552
114MP0005508_abnormal_skeleton_morphology0.77956416
115MP0003941_abnormal_skin_development0.76995674
116MP0000432_abnormal_head_morphology0.76983317
117MP0005257_abnormal_intraocular_pressure0.76703981
118MP0001529_abnormal_vocalization0.74610748
119MP0004133_heterotaxia0.74456420
120MP0000762_abnormal_tongue_morphology0.71199507
121MP0008995_early_reproductive_senescence0.70714562
122MP0001188_hyperpigmentation0.70128078
123MP0004197_abnormal_fetal_growth/weight/0.69425358
124MP0003567_abnormal_fetal_cardiomyocyte0.69415768
125MP0002127_abnormal_cardiovascular_syste0.69234976

Predicted human phenotypes

RankGene SetZ-score
1Congenital stationary night blindness (HP:0007642)5.99334147
2Chorioretinal atrophy (HP:0000533)4.33075816
3Bony spicule pigmentary retinopathy (HP:0007737)4.13949339
4Pendular nystagmus (HP:0012043)3.92821536
5Nephronophthisis (HP:0000090)3.39762598
6True hermaphroditism (HP:0010459)3.35190711
7Pancreatic cysts (HP:0001737)3.31720289
8Central scotoma (HP:0000603)3.27224109
9Pancreatic fibrosis (HP:0100732)3.25413832
10Abnormal rod and cone electroretinograms (HP:0008323)3.25155876
11Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)3.24639448
12Short 4th metacarpal (HP:0010044)3.24639448
13Scotoma (HP:0000575)3.03865903
14Midline defect of the nose (HP:0004122)2.98414166
15Absent rod-and cone-mediated responses on ERG (HP:0007688)2.87488384
16Molar tooth sign on MRI (HP:0002419)2.87029535
17Abnormality of midbrain morphology (HP:0002418)2.87029535
18Hepatoblastoma (HP:0002884)2.86445845
19Abnormality of the renal medulla (HP:0100957)2.76465337
20Abnormality of macular pigmentation (HP:0008002)2.71023585
21High anterior hairline (HP:0009890)2.69521397
22Dyschromatopsia (HP:0007641)2.62826146
23Abnormality of the 4th metacarpal (HP:0010012)2.61120782
24Aplasia/Hypoplasia of the optic nerve (HP:0008058)2.56415120
25Medial flaring of the eyebrow (HP:0010747)2.50871092
26Pigmentary retinal degeneration (HP:0001146)2.50151262
27Aplasia/Hypoplasia of the uvula (HP:0010293)2.47653090
28Attenuation of retinal blood vessels (HP:0007843)2.45028644
29Renal duplication (HP:0000075)2.44776244
30Meckel diverticulum (HP:0002245)2.44097552
31Abnormal number of incisors (HP:0011064)2.43896858
32Colon cancer (HP:0003003)2.43643216
33Vitreoretinal degeneration (HP:0000655)2.41457890
34Abnormality of the ileum (HP:0001549)2.38780909
35Anencephaly (HP:0002323)2.36419817
36Anophthalmia (HP:0000528)2.34466731
37Sclerocornea (HP:0000647)2.34230444
38Cutaneous finger syndactyly (HP:0010554)2.33237805
39Keratoconus (HP:0000563)2.32521454
40Increased corneal curvature (HP:0100692)2.32521454
41Severe visual impairment (HP:0001141)2.31661579
42Oligodactyly (hands) (HP:0001180)2.30247000
43Cone-rod dystrophy (HP:0000548)2.29142555
44Triphalangeal thumb (HP:0001199)2.28149638
45Preaxial hand polydactyly (HP:0001177)2.27731819
46Postaxial foot polydactyly (HP:0001830)2.27397635
47Septo-optic dysplasia (HP:0100842)2.26672985
48Decreased central vision (HP:0007663)2.26652694
49Ectopic kidney (HP:0000086)2.26195950
50Vaginal atresia (HP:0000148)2.23992819
51Genital tract atresia (HP:0001827)2.22643872
52Type II diabetes mellitus (HP:0005978)2.22555621
53Gait imbalance (HP:0002141)2.22067939
54Abnormality of the aortic arch (HP:0012303)2.20019444
55Renal hypoplasia (HP:0000089)2.14445119
56Abnormality of the phalanges of the hallux (HP:0010057)2.14057743
57Congenital primary aphakia (HP:0007707)2.13047978
58Stenosis of the external auditory canal (HP:0000402)2.12370073
59Aplasia/Hypoplasia of the tongue (HP:0010295)2.12229251
60Chronic hepatic failure (HP:0100626)2.11931494
61Nephroblastoma (Wilms tumor) (HP:0002667)2.09880410
62Cystic liver disease (HP:0006706)2.09601711
63Photophobia (HP:0000613)2.09597716
64Oligodactyly (HP:0012165)2.09141200
65Bifid tongue (HP:0010297)2.08826241
66Postaxial hand polydactyly (HP:0001162)2.08564346
67Abnormality of the phalanges of the 2nd finger (HP:0009541)2.08537087
68Absent septum pellucidum (HP:0001331)2.05709620
69Cutaneous syndactyly (HP:0012725)2.05531523
70Embryonal renal neoplasm (HP:0011794)2.04024909
71Abnormality of the metopic suture (HP:0005556)2.03036185
72Chromosomal breakage induced by crosslinking agents (HP:0003221)2.00679173
73Gastrointestinal atresia (HP:0002589)2.00332490
74Aplasia/Hypoplasia of the sternum (HP:0006714)1.99815226
75Abnormality of the proximal phalanges of the hand (HP:0009834)1.99566404
76Bilateral microphthalmos (HP:0007633)1.97979589
77Aqueductal stenosis (HP:0002410)1.97248682
78Esophageal atresia (HP:0002032)1.95967493
79Supernumerary spleens (HP:0009799)1.94824497
80Dandy-Walker malformation (HP:0001305)1.94152775
81Shawl scrotum (HP:0000049)1.92934698
82Abnormality of chromosome stability (HP:0003220)1.92287230
83Nephrogenic diabetes insipidus (HP:0009806)1.92065968
84Exotropia (HP:0000577)1.89648772
85Abnormality of the phalanges of the 5th finger (HP:0004213)1.89195221
86Chromsome breakage (HP:0040012)1.88932576
87Absent radius (HP:0003974)1.88261481
88Hyperglycinemia (HP:0002154)1.87603270
89Holoprosencephaly (HP:0001360)1.86038788
90Abnormality of the middle phalanges of the toes (HP:0010183)1.85668891
91Drooling (HP:0002307)1.83969624
92Narrow forehead (HP:0000341)1.83697331
93Absent forearm bone (HP:0003953)1.83056048
94Aplasia involving forearm bones (HP:0009822)1.83056048
95Hypoplastic pelvis (HP:0008839)1.82925070
96Type II lissencephaly (HP:0007260)1.82575218
97Elfin facies (HP:0004428)1.82238565
98Aplasia/Hypoplasia of the hallux (HP:0008362)1.82006483
99Abdominal situs inversus (HP:0003363)1.82004485
100Abnormality of abdominal situs (HP:0011620)1.82004485
101Growth hormone deficiency (HP:0000824)1.81151701
102Short hallux (HP:0010109)1.79077658
103Morphological abnormality of the middle ear (HP:0008609)1.78661054
104Abnormality of the duodenum (HP:0002246)1.78647036
105Aplasia/Hypoplasia of the tibia (HP:0005772)1.78228355
106Myelomeningocele (HP:0002475)1.78175558
107Scrotal hypoplasia (HP:0000046)1.77842013
108Megalencephaly (HP:0001355)1.77373178
109Abnormality of the labia minora (HP:0012880)1.76345069
110Febrile seizures (HP:0002373)1.75585537
111Increased number of teeth (HP:0011069)1.75186213
112Hemivertebrae (HP:0002937)1.75018809
113Male pseudohermaphroditism (HP:0000037)1.72874574
114Maternal diabetes (HP:0009800)1.72684917
115Macular degeneration (HP:0000608)1.70736761
116Congenital hepatic fibrosis (HP:0002612)1.70650939
117Abnormality of the renal cortex (HP:0011035)1.69567155
118Abnormal biliary tract physiology (HP:0012439)1.68942996
119Bile duct proliferation (HP:0001408)1.68942996
120Lissencephaly (HP:0001339)1.68636898
121Micropenis (HP:0000054)1.68353154
122Abolished electroretinogram (ERG) (HP:0000550)1.68344360
123Poor coordination (HP:0002370)1.67582251
124Posterior subcapsular cataract (HP:0007787)1.66050596
125Asymmetry of the thorax (HP:0001555)1.65832324
126Fibular aplasia (HP:0002990)1.65440180
127Choroideremia (HP:0001139)1.65028242
128Abnormality of the intervertebral disk (HP:0005108)1.64123531
129Small intestinal stenosis (HP:0012848)1.64116981
130Duodenal stenosis (HP:0100867)1.64116981
131Small hand (HP:0200055)1.64116084
132Absent thumb (HP:0009777)1.63956497
133Aplasia/Hypoplasia of the 5th finger (HP:0006262)1.63579220
134Abnormality of the carotid arteries (HP:0005344)1.63474602
135Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)1.63256319
136Abnormality of the septum pellucidum (HP:0007375)1.62064742
137Short 5th finger (HP:0009237)1.59836333
138Abnormality of the incisor (HP:0000676)1.57702544
139Rib fusion (HP:0000902)1.57700714
140Preaxial foot polydactyly (HP:0001841)1.57335134
141Diastasis recti (HP:0001540)1.56543615
142Protruding tongue (HP:0010808)1.56074032
143Germ cell neoplasia (HP:0100728)1.55549012
144Epileptic encephalopathy (HP:0200134)1.54461949
145Papillary thyroid carcinoma (HP:0002895)1.53995303
146Patellar aplasia (HP:0006443)1.52588728
147Amblyopia (HP:0000646)1.52045648
148Broad toe (HP:0001837)1.51624951
149Sacral dimple (HP:0000960)1.51618486
150Wide nasal bridge (HP:0000431)1.51379167
151Retinitis pigmentosa (HP:0000510)1.50599081
152Uterine leiomyosarcoma (HP:0002891)1.50350239
153Leiomyosarcoma (HP:0100243)1.50350239
154Coronal craniosynostosis (HP:0004440)1.49290028
155Broad-based gait (HP:0002136)1.48519737
156Volvulus (HP:0002580)1.48410798
157Intestinal atresia (HP:0011100)1.48258590
158Embryonal neoplasm (HP:0002898)1.47812475
159Intellectual disability, moderate (HP:0002342)1.47194261
160Abnormal lung lobation (HP:0002101)1.47013437
161Natal tooth (HP:0000695)1.46289531
162Tented upper lip vermilion (HP:0010804)1.46193747
163Renal dysplasia (HP:0000110)1.45443332
164Aplasia/Hypoplasia of the patella (HP:0006498)1.45075633
165Abnormality of the nasolacrimal system (HP:0000614)1.44958334
166Failure to thrive in infancy (HP:0001531)1.44426842
167Increased nuchal translucency (HP:0010880)1.44199696
168Vesicoureteral reflux (HP:0000076)1.42730879
169Optic nerve hypoplasia (HP:0000609)1.41336669
170Prominent metopic ridge (HP:0005487)1.41170351
171Abnormality of DNA repair (HP:0003254)1.40982834
172Progressive cerebellar ataxia (HP:0002073)1.40601789
173Patellar dislocation (HP:0002999)1.38782173

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK13.32281212
2EPHB22.98949717
3CASK2.55302117
4IRAK22.52275167
5FRK2.28911211
6MAP4K22.28054970
7MKNK12.26389467
8BMPR1B2.18911414
9ERBB32.13196322
10NUAK12.12980673
11SRPK12.08786758
12ZAK2.08591367
13TRIM282.07569844
14KSR11.99956048
15INSRR1.96734116
16GRK11.95403665
17DYRK21.94759741
18WNK31.93638168
19MKNK21.91777617
20MAPK131.85749713
21EPHA41.80291182
22CDC71.75896653
23BRD41.73600361
24PLK41.71914659
25WEE11.70497135
26NTRK31.67521111
27MAP3K101.61576870
28AKT31.58255519
29ADRBK21.52769983
30UHMK11.52288847
31EPHA31.52086248
32PRPF4B1.50445106
33MINK11.49403982
34ACVR1B1.48336452
35STK161.44306114
36LATS21.39579954
37ICK1.38357915
38VRK21.37204243
39PINK11.35998194
40PLK31.34151623
41MAP3K41.33797800
42VRK11.32927588
43SIK31.32051790
44NTRK21.31908760
45ERBB21.30686521
46SGK21.25571252
47TLK11.25172848
48MAP2K71.24457041
49SIK21.23868557
50CCNB11.20932059
51STK38L1.20339411
52SGK4941.19399301
53SGK2231.19399301
54PLK21.18331878
55PNCK1.17706589
56LATS11.17152705
57CSNK1G21.10791379
58BRAF1.09003063
59CDK81.05395116
60DYRK1A1.05370720
61CSNK1G11.01604132
62DYRK31.01491652
63NEK10.97864244
64BRSK20.96759270
65YES10.95751604
66STK390.94997725
67TAF10.93336716
68CSNK1G30.91017586
69PAK60.88871255
70WNK40.86237302
71NEK20.83763799
72CHEK20.83223343
73PDGFRA0.82097207
74DDR20.81554770
75TTK0.78515760
76CSNK1A1L0.77415885
77PRKD30.76918067
78BCR0.76876148
79PAK30.76453864
80ADRBK10.75553841
81PASK0.75281295
82PLK10.74957340
83TIE10.74901088
84STK30.74654507
85TAOK20.72227234
86TYRO30.71627702
87OXSR10.69971773
88RPS6KA40.69877323
89ATR0.68453649
90PRKCE0.67451177
91BRSK10.66738281
92PRKCZ0.64490768
93CDK10.64022311
94MAP2K40.63867394
95CDK180.63603733
96FGFR10.61698922
97DYRK1B0.60933070
98CDK140.59958746
99MAPK90.59760488
100CDK120.59590280
101CDK70.59194972
102ROCK20.59070684
103FLT30.58884935
104CDK30.58120857
105PKN10.57433892
106RPS6KA20.57332544
107BUB10.57306192
108PHKG20.55875299
109PHKG10.55875299
110BCKDK0.55767903
111ATM0.54817922
112CDK190.54614596
113CDK150.54505111
114SGK30.54134298
115AURKA0.52471478
116CHEK10.52387551
117CAMK1G0.52209686
118CDK20.52120833
119CDK50.51073546
120ROCK10.50960732
121SGK10.50876268
122CDC42BPA0.50449685
123CAMK40.49284168
124EIF2AK30.48796211
125PRKCG0.48377613
126IRAK10.47817065
127FGFR20.47728472
128GSK3B0.47665576
129CDK11A0.46344941
130CSNK1E0.45821567
131MAPK140.45511412
132TNIK0.45295739
133AKT20.44986179
134MAPK100.44572948
135TGFBR10.43374427
136FER0.42641800
137DAPK20.42218978
138CAMK2A0.42173545
139AURKB0.42160409
140PIK3CA0.41583187
141CSNK1A10.40151241
142NLK0.37456787
143PRKDC0.35932403
144CAMK10.35420901
145OBSCN0.34651399
146STK110.34586212

Predicted pathways (KEGG)

RankGene SetZ-score
1Phototransduction_Homo sapiens_hsa047446.73375047
2Non-homologous end-joining_Homo sapiens_hsa034502.51181061
3Basal cell carcinoma_Homo sapiens_hsa052172.40035633
4Nicotine addiction_Homo sapiens_hsa050332.35134997
5Axon guidance_Homo sapiens_hsa043602.27307462
6Hedgehog signaling pathway_Homo sapiens_hsa043402.01523440
7Propanoate metabolism_Homo sapiens_hsa006401.85546491
8mRNA surveillance pathway_Homo sapiens_hsa030151.84960457
9Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.82518660
10Protein export_Homo sapiens_hsa030601.81003747
11Hippo signaling pathway_Homo sapiens_hsa043901.80557559
12Oxidative phosphorylation_Homo sapiens_hsa001901.77236696
13Spliceosome_Homo sapiens_hsa030401.69851895
14Butanoate metabolism_Homo sapiens_hsa006501.69358803
15Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.67151450
16GABAergic synapse_Homo sapiens_hsa047271.60291119
17Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.60020248
18Wnt signaling pathway_Homo sapiens_hsa043101.58649292
19Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.58625061
20Parkinsons disease_Homo sapiens_hsa050121.54969140
21Steroid biosynthesis_Homo sapiens_hsa001001.52347412
22Circadian entrainment_Homo sapiens_hsa047131.51126377
23Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.44162164
24Dopaminergic synapse_Homo sapiens_hsa047281.43476692
25Melanogenesis_Homo sapiens_hsa049161.42218211
26Morphine addiction_Homo sapiens_hsa050321.41895233
27Synaptic vesicle cycle_Homo sapiens_hsa047211.40006787
28Nitrogen metabolism_Homo sapiens_hsa009101.39710869
29Glutamatergic synapse_Homo sapiens_hsa047241.39470775
30Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.38870501
31Endometrial cancer_Homo sapiens_hsa052131.36019559
32Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.34880009
33Cell cycle_Homo sapiens_hsa041101.32147457
34Olfactory transduction_Homo sapiens_hsa047401.30834637
35Long-term potentiation_Homo sapiens_hsa047201.29034107
36Huntingtons disease_Homo sapiens_hsa050161.28625681
37Cholinergic synapse_Homo sapiens_hsa047251.24504794
38Oocyte meiosis_Homo sapiens_hsa041141.22540001
39Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.22221323
40Colorectal cancer_Homo sapiens_hsa052101.21885965
41Selenocompound metabolism_Homo sapiens_hsa004501.21702176
42Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.20281024
43Alcoholism_Homo sapiens_hsa050341.18325403
44Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.17981825
45Linoleic acid metabolism_Homo sapiens_hsa005911.17837182
46Gap junction_Homo sapiens_hsa045401.15270016
47Notch signaling pathway_Homo sapiens_hsa043301.14886055
48Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.14323681
49MicroRNAs in cancer_Homo sapiens_hsa052061.11938433
50Amphetamine addiction_Homo sapiens_hsa050311.10978309
51Basal transcription factors_Homo sapiens_hsa030221.10642107
52Ribosome_Homo sapiens_hsa030101.10156498
53Mismatch repair_Homo sapiens_hsa034301.09541457
54Glioma_Homo sapiens_hsa052141.07495104
55Nucleotide excision repair_Homo sapiens_hsa034201.07290179
56Serotonergic synapse_Homo sapiens_hsa047261.05139566
57RNA transport_Homo sapiens_hsa030131.05136267
58Maturity onset diabetes of the young_Homo sapiens_hsa049501.04460558
59Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.03861468
60Taste transduction_Homo sapiens_hsa047421.03550007
61Oxytocin signaling pathway_Homo sapiens_hsa049211.03271984
62Ether lipid metabolism_Homo sapiens_hsa005651.03250278
63Cardiac muscle contraction_Homo sapiens_hsa042601.03141084
64Cocaine addiction_Homo sapiens_hsa050301.02886360
65Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.02753782
66Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.01522011
67Circadian rhythm_Homo sapiens_hsa047101.01132056
68Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.00646958
69Thyroid hormone signaling pathway_Homo sapiens_hsa049190.99418553
70Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.99141617
71Tryptophan metabolism_Homo sapiens_hsa003800.98951205
72RNA degradation_Homo sapiens_hsa030180.98208736
73RNA polymerase_Homo sapiens_hsa030200.96734194
74Fanconi anemia pathway_Homo sapiens_hsa034600.95306652
75Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.95143933
76Proteasome_Homo sapiens_hsa030500.94594979
77alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.93821219
78Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.93342830
79TGF-beta signaling pathway_Homo sapiens_hsa043500.93200196
80Dilated cardiomyopathy_Homo sapiens_hsa054140.92252000
81Insulin secretion_Homo sapiens_hsa049110.92099673
82Retinol metabolism_Homo sapiens_hsa008300.89923717
83Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.89511954
84Cysteine and methionine metabolism_Homo sapiens_hsa002700.88855290
85Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.88553459
86Adherens junction_Homo sapiens_hsa045200.88135836
87Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.88129772
88Alzheimers disease_Homo sapiens_hsa050100.88035246
89DNA replication_Homo sapiens_hsa030300.86812757
90Melanoma_Homo sapiens_hsa052180.86714923
91Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.86258252
92ErbB signaling pathway_Homo sapiens_hsa040120.83670865
93Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.83381536
94Renin secretion_Homo sapiens_hsa049240.82174052
95cGMP-PKG signaling pathway_Homo sapiens_hsa040220.81935451
96Caffeine metabolism_Homo sapiens_hsa002320.81185063
97Long-term depression_Homo sapiens_hsa047300.81165531
98Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.80745447
99Base excision repair_Homo sapiens_hsa034100.80655112
100Lysine degradation_Homo sapiens_hsa003100.79573712
101Tight junction_Homo sapiens_hsa045300.77902618
102Central carbon metabolism in cancer_Homo sapiens_hsa052300.76846304
103Pyruvate metabolism_Homo sapiens_hsa006200.76339207
104Non-small cell lung cancer_Homo sapiens_hsa052230.76205490
105mTOR signaling pathway_Homo sapiens_hsa041500.75537506
106Chemical carcinogenesis_Homo sapiens_hsa052040.74892720
107Peroxisome_Homo sapiens_hsa041460.72007695
108p53 signaling pathway_Homo sapiens_hsa041150.71582421
109Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.70342613
110Aldosterone synthesis and secretion_Homo sapiens_hsa049250.70053599
111cAMP signaling pathway_Homo sapiens_hsa040240.69789624
112Steroid hormone biosynthesis_Homo sapiens_hsa001400.69410366
113Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.69333127
114Fatty acid elongation_Homo sapiens_hsa000620.69154014
115Pathways in cancer_Homo sapiens_hsa052000.69063846
116Purine metabolism_Homo sapiens_hsa002300.68942626
117Pyrimidine metabolism_Homo sapiens_hsa002400.67652993
118Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.66715153
119Renal cell carcinoma_Homo sapiens_hsa052110.65586292
120Chronic myeloid leukemia_Homo sapiens_hsa052200.65077878
121Systemic lupus erythematosus_Homo sapiens_hsa053220.64650049
122Estrogen signaling pathway_Homo sapiens_hsa049150.64450824
123GnRH signaling pathway_Homo sapiens_hsa049120.63325974
124Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.61557363
125Rap1 signaling pathway_Homo sapiens_hsa040150.61247916
126Prostate cancer_Homo sapiens_hsa052150.60459121
127Proteoglycans in cancer_Homo sapiens_hsa052050.60017079
128Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.59454479
129beta-Alanine metabolism_Homo sapiens_hsa004100.58391008
130Primary bile acid biosynthesis_Homo sapiens_hsa001200.58185979
131Regulation of autophagy_Homo sapiens_hsa041400.57393068
132Salivary secretion_Homo sapiens_hsa049700.56972221
133Type II diabetes mellitus_Homo sapiens_hsa049300.55083059
134Choline metabolism in cancer_Homo sapiens_hsa052310.54157389
135Homologous recombination_Homo sapiens_hsa034400.53973299
136Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.53524049
137Fat digestion and absorption_Homo sapiens_hsa049750.52965344
138Ras signaling pathway_Homo sapiens_hsa040140.52647174
139Phospholipase D signaling pathway_Homo sapiens_hsa040720.51940118
140Thyroid cancer_Homo sapiens_hsa052160.51862112
141Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.50749792
142Calcium signaling pathway_Homo sapiens_hsa040200.50629779
143Phosphatidylinositol signaling system_Homo sapiens_hsa040700.50546041
144HTLV-I infection_Homo sapiens_hsa051660.50319937
145Transcriptional misregulation in cancer_Homo sapiens_hsa052020.50015510
146Neurotrophin signaling pathway_Homo sapiens_hsa047220.47901969
147Gastric acid secretion_Homo sapiens_hsa049710.47255001
148Pentose and glucuronate interconversions_Homo sapiens_hsa000400.46787072
149MAPK signaling pathway_Homo sapiens_hsa040100.46561923
150Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.46543823
151Glycerolipid metabolism_Homo sapiens_hsa005610.46525591
152Metabolic pathways_Homo sapiens_hsa011000.46425228
153Fatty acid metabolism_Homo sapiens_hsa012120.40165606

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