SLAIN1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1fatty acid elongation (GO:0030497)7.30919431
2ensheathment of neurons (GO:0007272)6.94078754
3axon ensheathment (GO:0008366)6.94078754
4myelination (GO:0042552)6.91615777
5long-chain fatty acid biosynthetic process (GO:0042759)6.23267231
6postsynaptic membrane organization (GO:0001941)5.84002439
7myelin maintenance (GO:0043217)5.75174152
8negative regulation of neurotransmitter secretion (GO:0046929)5.50466430
9synaptic vesicle maturation (GO:0016188)5.34669077
10negative regulation of neurotransmitter transport (GO:0051589)5.33396517
11establishment of mitochondrion localization (GO:0051654)5.14887629
12positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.12903349
13ionotropic glutamate receptor signaling pathway (GO:0035235)4.99063804
14cellular potassium ion homeostasis (GO:0030007)4.82257454
15membrane depolarization during cardiac muscle cell action potential (GO:0086012)4.78843234
16glycerophospholipid catabolic process (GO:0046475)4.75193768
17synaptic vesicle docking involved in exocytosis (GO:0016081)4.71937176
18locomotory exploration behavior (GO:0035641)4.71511985
19oligodendrocyte differentiation (GO:0048709)4.67316521
20regulation of synaptic vesicle exocytosis (GO:2000300)4.61664735
21synaptic vesicle exocytosis (GO:0016079)4.57779144
22vocalization behavior (GO:0071625)4.46829916
23glutamate secretion (GO:0014047)4.43510960
24apical protein localization (GO:0045176)4.38865990
25sodium ion export (GO:0071436)4.30255028
26regulation of collateral sprouting (GO:0048670)4.30172650
27asymmetric protein localization (GO:0008105)4.29568719
28negative regulation of protein localization to cell surface (GO:2000009)4.26934357
29cholesterol biosynthetic process (GO:0006695)4.25926184
30response to methylmercury (GO:0051597)4.25523703
31positive regulation of oligodendrocyte differentiation (GO:0048714)4.21579171
32regulation of short-term neuronal synaptic plasticity (GO:0048172)4.19915296
33neurotransmitter-gated ion channel clustering (GO:0072578)4.19033398
34auditory behavior (GO:0031223)4.13018507
35regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.12881239
36presynaptic membrane organization (GO:0097090)4.11794058
37exploration behavior (GO:0035640)4.11581515
38eye photoreceptor cell differentiation (GO:0001754)4.10939537
39photoreceptor cell differentiation (GO:0046530)4.10939537
40regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.06837826
41positive regulation of potassium ion transmembrane transporter activity (GO:1901018)4.01908332
42neurotransmitter secretion (GO:0007269)3.99592510
43glutamate receptor signaling pathway (GO:0007215)3.98014180
44regulation of synaptic vesicle transport (GO:1902803)3.93453712
45regulation of neuronal synaptic plasticity (GO:0048168)3.91612372
46creatine metabolic process (GO:0006600)3.90559748
47synaptic transmission, glutamatergic (GO:0035249)3.89964554
48potassium ion import (GO:0010107)3.85033436
49amyloid precursor protein metabolic process (GO:0042982)3.78559041
50protein localization to synapse (GO:0035418)3.77162710
51presynaptic membrane assembly (GO:0097105)3.74654766
52sterol biosynthetic process (GO:0016126)3.74308099
53potassium ion homeostasis (GO:0055075)3.73930407
54response to redox state (GO:0051775)3.73423921
55mechanosensory behavior (GO:0007638)3.70663752
56regulation of glutamate receptor signaling pathway (GO:1900449)3.70308418
57L-amino acid import (GO:0043092)3.70198664
58astrocyte development (GO:0014002)3.68996835
59substantia nigra development (GO:0021762)3.68045220
60negative regulation of peptidyl-threonine phosphorylation (GO:0010801)3.65739784
61membrane tubulation (GO:0097320)3.65286486
62gamma-aminobutyric acid transport (GO:0015812)3.62734445
63positive regulation of synapse maturation (GO:0090129)3.59313191
64isoprenoid biosynthetic process (GO:0008299)3.59087945
65adult walking behavior (GO:0007628)3.57242070
66regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.55678495
67acidic amino acid transport (GO:0015800)3.55416038
68protein palmitoylation (GO:0018345)3.54257130
69positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.53215193
70neuron-neuron synaptic transmission (GO:0007270)3.51024545
71response to auditory stimulus (GO:0010996)3.49762543
72regulation of long-term neuronal synaptic plasticity (GO:0048169)3.43114915
73regulation of synapse structural plasticity (GO:0051823)3.42336946
74magnesium ion transport (GO:0015693)3.42307774
75long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)3.42167888
76peripheral nervous system axon ensheathment (GO:0032292)3.41556011
77myelination in peripheral nervous system (GO:0022011)3.41556011
78cerebral cortex radially oriented cell migration (GO:0021799)3.41402598
79negative regulation of synaptic transmission, GABAergic (GO:0032229)3.41332673
80response to lipoprotein particle (GO:0055094)3.40384712
81positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.37848684
82dendrite morphogenesis (GO:0048813)3.37386905
83regulation of excitatory postsynaptic membrane potential (GO:0060079)3.37331489
84negative regulation of execution phase of apoptosis (GO:1900118)3.35898839
85regulation of synaptic transmission, glutamatergic (GO:0051966)3.34420410
86positive regulation of dendritic spine development (GO:0060999)3.34367994
87axonal fasciculation (GO:0007413)3.33845290
88neuron cell-cell adhesion (GO:0007158)3.33607485
89positive regulation of membrane potential (GO:0045838)3.33162946
90peptidyl-tyrosine autophosphorylation (GO:0038083)3.31220938
91neurotransmitter transport (GO:0006836)3.28890690
92membrane assembly (GO:0071709)3.28100659
93long-chain fatty-acyl-CoA metabolic process (GO:0035336)3.27644734
94C4-dicarboxylate transport (GO:0015740)3.27580920
95regulation of lipoprotein metabolic process (GO:0050746)3.26785617
96long-term synaptic potentiation (GO:0060291)3.24318392
97microtubule polymerization or depolymerization (GO:0031109)3.24146543
98cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.23382965
99import into cell (GO:0098657)3.19497496
100neuromuscular process controlling balance (GO:0050885)3.18884330
101positive regulation of dendritic spine morphogenesis (GO:0061003)3.18292374
102neuronal action potential propagation (GO:0019227)3.17177158
103axon development (GO:0061564)3.16140583
104negative regulation of axonogenesis (GO:0050771)3.16133500
105regulation of postsynaptic membrane potential (GO:0060078)3.16116589
106long-term memory (GO:0007616)3.14969630
107negative regulation of dendrite morphogenesis (GO:0050774)3.14482127
108peptidyl-cysteine modification (GO:0018198)3.14466296
109regulation of dendritic spine morphogenesis (GO:0061001)3.12553056
110L-glutamate transport (GO:0015813)3.12543952
111GPI anchor biosynthetic process (GO:0006506)3.12396441
112regulation of neurotransmitter secretion (GO:0046928)3.12179478
113negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.09357238
114nerve growth factor signaling pathway (GO:0038180)3.08962739
115regulation of neurotransmitter levels (GO:0001505)3.08149788
116regulation of synaptic plasticity (GO:0048167)3.07735546
117dendritic spine morphogenesis (GO:0060997)3.06669979
118regulation of neurotransmitter transport (GO:0051588)3.05666264
119regulation of dendritic spine development (GO:0060998)3.04993590
120negative regulation of dendrite development (GO:2000171)3.03909397
121negative regulation of JUN kinase activity (GO:0043508)3.03888239
122cellular sodium ion homeostasis (GO:0006883)3.01373367
123regulation of voltage-gated calcium channel activity (GO:1901385)3.01093772
124organ growth (GO:0035265)3.00707329
125GPI anchor metabolic process (GO:0006505)2.99664251
126cerebellar Purkinje cell differentiation (GO:0021702)2.99199793
127gamma-aminobutyric acid signaling pathway (GO:0007214)2.99068582
128glycosylceramide metabolic process (GO:0006677)2.97538248
129Golgi to endosome transport (GO:0006895)2.96464924
130cell communication by electrical coupling (GO:0010644)2.96178925
131transmission of nerve impulse (GO:0019226)2.93475488
132regulation of synaptic transmission, GABAergic (GO:0032228)2.92836753
133negative regulation of macroautophagy (GO:0016242)2.88802487
134limb bud formation (GO:0060174)2.86159811
135fatty-acyl-CoA biosynthetic process (GO:0046949)2.84931094
136negative regulation of inclusion body assembly (GO:0090084)2.84825058
137positive regulation of glial cell differentiation (GO:0045687)2.82232133
138preassembly of GPI anchor in ER membrane (GO:0016254)2.79560059
139protein localization to endosome (GO:0036010)2.76818984
140chaperone-mediated protein transport (GO:0072321)2.75418514
141substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.73391002
142substrate-independent telencephalic tangential migration (GO:0021826)2.73391002
143fatty-acyl-CoA metabolic process (GO:0035337)2.71575647
144mitochondrion transport along microtubule (GO:0047497)2.69716077
145establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.69716077
146virion attachment to host cell (GO:0019062)2.69578874
147adhesion of symbiont to host cell (GO:0044650)2.69578874
148amino acid import (GO:0043090)2.69056448
149positive regulation of gliogenesis (GO:0014015)2.67842032
150glial cell development (GO:0021782)2.65932706
151regulation of catecholamine metabolic process (GO:0042069)2.63071021
152regulation of dopamine metabolic process (GO:0042053)2.63071021
153peripheral nervous system development (GO:0007422)2.62734697
154neuron remodeling (GO:0016322)2.61187946
155amyloid precursor protein catabolic process (GO:0042987)2.60136107
156neurotransmitter uptake (GO:0001504)2.59236066
157positive regulation of neurological system process (GO:0031646)2.58532407
158microtubule severing (GO:0051013)2.58265150
159positive regulation of action potential (GO:0045760)2.55946002
160positive regulation of epidermal growth factor-activated receptor activity (GO:0045741)2.52581741
161mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686)2.52504655
162positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:19021102.52504655
163cerebellar granule cell differentiation (GO:0021707)2.51877764
164histone H2B ubiquitination (GO:0033523)2.51364054
165neuronal ion channel clustering (GO:0045161)2.49701842
166glial cell differentiation (GO:0010001)2.49570142
167neuron recognition (GO:0008038)2.49401154
168dopamine biosynthetic process (GO:0042416)2.46550160
169enteric nervous system development (GO:0048484)2.45711813
170neural nucleus development (GO:0048857)2.45383185
171glycine transport (GO:0015816)2.43284011
172central nervous system myelination (GO:0022010)11.9450672
173axon ensheathment in central nervous system (GO:0032291)11.9450672

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1GBX2_23144817_ChIP-Seq_PC3_Human3.42560476
2EZH2_22144423_ChIP-Seq_EOC_Human3.02503557
3SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse2.65518567
4TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.65060583
5TAF15_26573619_Chip-Seq_HEK293_Human2.41013155
6GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.40546529
7HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.40041727
8E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.34746147
9CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.31557324
10JARID2_20064375_ChIP-Seq_MESCs_Mouse2.26733899
11SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.16096044
12OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse2.15294320
13SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.09482317
14ZFP57_27257070_Chip-Seq_ESCs_Mouse1.99514602
15VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.97670629
16MTF2_20144788_ChIP-Seq_MESCs_Mouse1.97570771
17AR_21572438_ChIP-Seq_LNCaP_Human1.94447096
18EZH2_27304074_Chip-Seq_ESCs_Mouse1.93155361
19SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.90815665
20RNF2_18974828_ChIP-Seq_MESCs_Mouse1.87767726
21EZH2_18974828_ChIP-Seq_MESCs_Mouse1.87767726
22CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.85904919
23ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.84524570
24* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.78861438
25SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.78778452
26ER_23166858_ChIP-Seq_MCF-7_Human1.75455942
27EZH2_27294783_Chip-Seq_ESCs_Mouse1.73732287
28SUZ12_27294783_Chip-Seq_ESCs_Mouse1.73675182
29RNF2_27304074_Chip-Seq_ESCs_Mouse1.72497334
30SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.69742189
31RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.69433064
32GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.68774295
33SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.65824894
34MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.62825658
35RARB_27405468_Chip-Seq_BRAIN_Mouse1.61986513
36SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.56656260
37LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.56219112
38* STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.55169744
39GATA1_26923725_Chip-Seq_HPCs_Mouse1.54825726
40VDR_22108803_ChIP-Seq_LS180_Human1.54598160
41FUS_26573619_Chip-Seq_HEK293_Human1.53872132
42JARID2_20075857_ChIP-Seq_MESCs_Mouse1.53325325
43CTBP1_25329375_ChIP-Seq_LNCAP_Human1.52742500
44EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.50207867
45POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.48591370
46TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.48591370
47CBX2_27304074_Chip-Seq_ESCs_Mouse1.45580954
48* SMAD3_21741376_ChIP-Seq_EPCs_Human1.44823426
49EED_16625203_ChIP-ChIP_MESCs_Mouse1.44811123
50RING1B_27294783_Chip-Seq_ESCs_Mouse1.44793910
51REST_21632747_ChIP-Seq_MESCs_Mouse1.44156266
52CTBP2_25329375_ChIP-Seq_LNCAP_Human1.42626779
53CDX2_19796622_ChIP-Seq_MESCs_Mouse1.42581688
54SOX2_21211035_ChIP-Seq_LN229_Gbm1.39794602
55STAT3_23295773_ChIP-Seq_U87_Human1.39631054
56TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.39628061
57PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.37727386
58YAP1_20516196_ChIP-Seq_MESCs_Mouse1.37610511
59RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.37232600
60SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.37118598
61DROSHA_22980978_ChIP-Seq_HELA_Human1.36804995
62RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.32654610
63RNF2_27304074_Chip-Seq_NSC_Mouse1.31507461
64SOX9_26525672_Chip-Seq_HEART_Mouse1.31161286
65P53_22127205_ChIP-Seq_FIBROBLAST_Human1.30948891
66PIAS1_25552417_ChIP-Seq_VCAP_Human1.29768424
67P300_19829295_ChIP-Seq_ESCs_Human1.28884331
68BMI1_23680149_ChIP-Seq_NPCS_Mouse1.27815568
69SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.27527026
70RING1B_27294783_Chip-Seq_NPCs_Mouse1.25376956
71* AR_19668381_ChIP-Seq_PC3_Human1.25200249
72TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.24718834
73TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.24578529
74AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.24551719
75NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.24519853
76PRDM14_20953172_ChIP-Seq_ESCs_Human1.23213644
77GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.22218118
78RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.21191924
79NANOG_18555785_Chip-Seq_ESCs_Mouse1.20075434
80TAL1_26923725_Chip-Seq_HPCs_Mouse1.19439065
81TCF4_23295773_ChIP-Seq_U87_Human1.18367016
82REST_18959480_ChIP-ChIP_MESCs_Mouse1.17372230
83CMYC_18555785_Chip-Seq_ESCs_Mouse1.17236837
84RBPJ_22232070_ChIP-Seq_NCS_Mouse1.16692129
85IGF1R_20145208_ChIP-Seq_DFB_Human1.16683319
86SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.15881743
87MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.14906324
88PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.14762299
89TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.12689992
90MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.12658839
91SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.11944753
92SMAD4_21799915_ChIP-Seq_A2780_Human1.10962460
93EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.10867452
94CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10795966
95CTNNB1_20460455_ChIP-Seq_HCT116_Human1.10668849
96EOMES_21245162_ChIP-Seq_HESCs_Human1.07874609
97SUZ12_18555785_Chip-Seq_ESCs_Mouse1.07364814
98* OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.07243922
99SMAD3_21741376_ChIP-Seq_ESCs_Human1.06887583
100LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.06326731
101* EWS_26573619_Chip-Seq_HEK293_Human1.06011129
102SALL1_21062744_ChIP-ChIP_HESCs_Human1.04908776
103AR_25329375_ChIP-Seq_VCAP_Human1.04452895
104TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.03364091
105TBL1_22424771_ChIP-Seq_293T_Human1.03116816
106* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.02000824
107* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.01987242
108RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.99960350
109* UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.98841487
110P300_18555785_Chip-Seq_ESCs_Mouse0.98838014
111TOP2B_26459242_ChIP-Seq_MCF-7_Human0.97567355
112* KDM2B_26808549_Chip-Seq_REH_Human0.97496890
113POU5F1_16153702_ChIP-ChIP_HESCs_Human0.97088231
114NANOG_19829295_ChIP-Seq_ESCs_Human0.95020752
115SOX2_19829295_ChIP-Seq_ESCs_Human0.95020752
116PCGF2_27294783_Chip-Seq_ESCs_Mouse0.94892785
117EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.94876294
118CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.94428228
119NR3C1_21868756_ChIP-Seq_MCF10A_Human0.93724650
120SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.93652529
121NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.93604166
122RUNX2_22187159_ChIP-Seq_PCA_Human0.93512878
123KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.93507610
124FLI1_27457419_Chip-Seq_LIVER_Mouse0.92880367
125TP53_16413492_ChIP-PET_HCT116_Human0.92699470
126PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.92590225
127SMAD4_21741376_ChIP-Seq_EPCs_Human0.92329717
128WT1_19549856_ChIP-ChIP_CCG9911_Human0.91407156
129EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.90374188
130PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.87858245
131ARNT_22903824_ChIP-Seq_MCF-7_Human0.87339071
132NR3C1_23031785_ChIP-Seq_PC12_Mouse0.87096091

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000920_abnormal_myelination5.26819416
2MP0003880_abnormal_central_pattern4.40415869
3MP0003950_abnormal_plasma_membrane3.60076905
4MP0004270_analgesia3.50948171
5MP0001529_abnormal_vocalization3.41827697
6MP0004859_abnormal_synaptic_plasticity2.88410438
7MP0004885_abnormal_endolymph2.85177737
8MP0001905_abnormal_dopamine_level2.81571223
9MP0003329_amyloid_beta_deposits2.69704029
10MP0003690_abnormal_glial_cell2.66636022
11MP0002272_abnormal_nervous_system2.60526594
12MP0001486_abnormal_startle_reflex2.57916328
13MP0004742_abnormal_vestibular_system2.50219052
14MP0000778_abnormal_nervous_system2.42360629
15MP0002064_seizures2.33025578
16MP0005451_abnormal_body_composition2.28134508
17MP0003634_abnormal_glial_cell2.27306553
18MP0001485_abnormal_pinna_reflex2.23019299
19MP0004142_abnormal_muscle_tone2.20018246
20MP0003635_abnormal_synaptic_transmissio2.18841282
21MP0005423_abnormal_somatic_nervous2.16281003
22MP0005171_absent_coat_pigmentation2.14298451
23MP0003136_yellow_coat_color2.10049255
24MP0001984_abnormal_olfaction2.08141919
25MP0009745_abnormal_behavioral_response1.92224411
26MP0002734_abnormal_mechanical_nocicepti1.88818277
27MP0002229_neurodegeneration1.85706139
28MP0005410_abnormal_fertilization1.83045104
29MP0003632_abnormal_nervous_system1.79553008
30MP0010678_abnormal_skin_adnexa1.79060173
31MP0009046_muscle_twitch1.73086689
32MP0000462_abnormal_digestive_system1.71724776
33MP0002063_abnormal_learning/memory/cond1.65796133
34MP0005409_darkened_coat_color1.63148979
35MP0008260_abnormal_autophagy1.61666795
36MP0000955_abnormal_spinal_cord1.59270264
37MP0002572_abnormal_emotion/affect_behav1.58060365
38MP0000383_abnormal_hair_follicle1.49433913
39MP0004043_abnormal_pH_regulation1.49029297
40MP0002882_abnormal_neuron_morphology1.48783944
41MP0008569_lethality_at_weaning1.45828060
42MP0000569_abnormal_digit_pigmentation1.45666457
43MP0004924_abnormal_behavior1.44264925
44MP0005386_behavior/neurological_phenoty1.44264925
45MP0001970_abnormal_pain_threshold1.42191131
46MP0003631_nervous_system_phenotype1.40853740
47MP0002066_abnormal_motor_capabilities/c1.38246716
48MP0004381_abnormal_hair_follicle1.36195969
49MP0002067_abnormal_sensory_capabilities1.32265899
50MP0001440_abnormal_grooming_behavior1.31351995
51MP0001851_eye_inflammation1.30345884
52MP0002638_abnormal_pupillary_reflex1.29673048
53MP0004134_abnormal_chest_morphology1.28428059
54MP0002752_abnormal_somatic_nervous1.21018710
55MP0001963_abnormal_hearing_physiology1.20451105
56MP0001346_abnormal_lacrimal_gland1.18575116
57MP0003633_abnormal_nervous_system1.17819552
58MP0002733_abnormal_thermal_nociception1.17410297
59MP0005551_abnormal_eye_electrophysiolog1.17211186
60MP0000604_amyloidosis1.16940343
61MP0003122_maternal_imprinting1.14552532
62MP0000566_synostosis1.13963163
63MP0003938_abnormal_ear_development1.13455429
64MP0001188_hyperpigmentation1.10751244
65MP0006276_abnormal_autonomic_nervous1.09456260
66MP0005408_hypopigmentation1.08094454
67MP0001299_abnormal_eye_distance/1.07745814
68MP0001968_abnormal_touch/_nociception1.07540753
69MP0003937_abnormal_limbs/digits/tail_de1.05265124
70MP0003123_paternal_imprinting1.05218071
71MP0002152_abnormal_brain_morphology1.03982051
72MP0001502_abnormal_circadian_rhythm0.96634133
73MP0003121_genomic_imprinting0.96126091
74MP0000747_muscle_weakness0.95745862
75MP0002184_abnormal_innervation0.93154154
76MP0002822_catalepsy0.92589808
77MP0006072_abnormal_retinal_apoptosis0.91689093
78MP0002909_abnormal_adrenal_gland0.91247738
79MP0003879_abnormal_hair_cell0.90047085
80MP0000579_abnormal_nail_morphology0.88927759
81MP0002653_abnormal_ependyma_morphology0.88574241
82MP0002736_abnormal_nociception_after0.88175333
83MP0005195_abnormal_posterior_eye0.87829551
84MP0005646_abnormal_pituitary_gland0.86925770
85MP0000631_abnormal_neuroendocrine_gland0.86711871
86MP0000647_abnormal_sebaceous_gland0.86612959
87MP0009780_abnormal_chondrocyte_physiolo0.85089926
88MP0002735_abnormal_chemical_nociception0.85013942
89MP0002102_abnormal_ear_morphology0.84969612
90MP0004185_abnormal_adipocyte_glucose0.84470785
91MP0003718_maternal_effect0.83742263
92MP0008057_abnormal_DNA_replication0.82708235
93MP0002249_abnormal_larynx_morphology0.81135489
94MP0002557_abnormal_social/conspecific_i0.80425256
95MP0008877_abnormal_DNA_methylation0.78699657
96MP0003698_abnormal_male_reproductive0.77520423
97MP0010769_abnormal_survival0.76602882
98MP0003861_abnormal_nervous_system0.76522083
99MP0010770_preweaning_lethality0.76177736
100MP0002082_postnatal_lethality0.76177736
101MP0004145_abnormal_muscle_electrophysio0.75799668
102MP0000026_abnormal_inner_ear0.75433387
103MP0004811_abnormal_neuron_physiology0.75206374
104MP0001661_extended_life_span0.74998858
105MP0001501_abnormal_sleep_pattern0.74590468
106MP0003119_abnormal_digestive_system0.74516754
107MP0010768_mortality/aging0.73319506
108MP0002069_abnormal_eating/drinking_beha0.73015733
109MP0004147_increased_porphyrin_level0.71455453
110MP0005645_abnormal_hypothalamus_physiol0.71036662
111MP0001943_abnormal_respiration0.70338960
112MP0001177_atelectasis0.69600251
113MP0003787_abnormal_imprinting0.68188648
114MP0006292_abnormal_olfactory_placode0.66784256
115MP0002751_abnormal_autonomic_nervous0.66539057
116MP0005187_abnormal_penis_morphology0.65033800
117MP0001340_abnormal_eyelid_morphology0.64854864
118MP0001348_abnormal_lacrimal_gland0.64774576
119MP0000639_abnormal_adrenal_gland0.63893683
120MP0005394_taste/olfaction_phenotype0.63668471
121MP0005499_abnormal_olfactory_system0.63668471
122MP0005310_abnormal_salivary_gland0.63002042
123MP0001929_abnormal_gametogenesis0.62955102
124MP0000537_abnormal_urethra_morphology0.62375320
125MP0002081_perinatal_lethality0.59585007
126MP0002234_abnormal_pharynx_morphology0.59322869
127MP0003890_abnormal_embryonic-extraembry0.58399435
128MP0005623_abnormal_meninges_morphology0.56677145
129MP0005253_abnormal_eye_physiology0.56289447
130MP0001986_abnormal_taste_sensitivity0.53808684
131MP0005167_abnormal_blood-brain_barrier0.50648817
132MP0002233_abnormal_nose_morphology0.50552810

Predicted human phenotypes

RankGene SetZ-score
1Degeneration of the lateral corticospinal tracts (HP:0002314)6.91800286
2Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)6.91800286
3Neurofibrillary tangles (HP:0002185)6.60432771
4Abnormality of the corticospinal tract (HP:0002492)5.42447828
5Peripheral hypomyelination (HP:0007182)4.90797990
6Cerebral inclusion bodies (HP:0100314)4.82824345
7Sensory axonal neuropathy (HP:0003390)4.57151842
8Cerebral hypomyelination (HP:0006808)4.56534345
9Febrile seizures (HP:0002373)4.47396328
10Parakeratosis (HP:0001036)4.31273030
11Supranuclear gaze palsy (HP:0000605)4.12699431
12Epileptic encephalopathy (HP:0200134)4.05617489
13Focal seizures (HP:0007359)4.03551163
14Spastic gait (HP:0002064)3.94434010
15Onion bulb formation (HP:0003383)3.89784059
16Insidious onset (HP:0003587)3.83750464
17Termporal pattern (HP:0011008)3.83750464
18Abnormal auditory evoked potentials (HP:0006958)3.79776348
19Congenital nonbullous ichthyosiform erythroderma (HP:0007479)3.63746873
20Dysmetria (HP:0001310)3.52356281
21Myokymia (HP:0002411)3.44720861
22Intention tremor (HP:0002080)3.29047430
23Ankle clonus (HP:0011448)3.27845936
24Hyperventilation (HP:0002883)3.23509769
25Diplopia (HP:0000651)3.22731296
26Abnormality of binocular vision (HP:0011514)3.22731296
27Retinal dysplasia (HP:0007973)3.09166358
28Truncal ataxia (HP:0002078)3.06277248
29CNS hypomyelination (HP:0003429)3.06102130
30Alacrima (HP:0000522)3.03659287
31Slow saccadic eye movements (HP:0000514)2.99943823
32Generalized tonic-clonic seizures (HP:0002069)2.98689860
33Impaired vibration sensation in the lower limbs (HP:0002166)2.92113277
34Absent septum pellucidum (HP:0001331)2.87830838
35Segmental peripheral demyelination/remyelination (HP:0003481)2.84478210
36Hemiparesis (HP:0001269)2.82978716
37Drooling (HP:0002307)2.79680768
38Hypoplastic pelvis (HP:0008839)2.79085746
39Thickened helices (HP:0000391)2.78071871
40Progressive cerebellar ataxia (HP:0002073)2.77879801
41Scanning speech (HP:0002168)2.77321004
42Morphological abnormality of the inner ear (HP:0011390)2.74568551
43Leukodystrophy (HP:0002415)2.70521850
44Anteriorly placed anus (HP:0001545)2.64544605
45Excessive salivation (HP:0003781)2.61617121
46Dysdiadochokinesis (HP:0002075)2.60785812
47Spastic tetraparesis (HP:0001285)2.59010271
48Hemiplegia (HP:0002301)2.57166264
49Akinesia (HP:0002304)2.56476453
50Focal motor seizures (HP:0011153)2.55846288
51Dialeptic seizures (HP:0011146)2.55681306
52Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.52278192
53Spastic paraparesis (HP:0002313)2.52074377
54Abnormal eating behavior (HP:0100738)2.51712596
55Poor eye contact (HP:0000817)2.49857562
56Decreased lacrimation (HP:0000633)2.48942302
57Absent speech (HP:0001344)2.46626013
58Absence seizures (HP:0002121)2.45627516
59Abnormality of the septum pellucidum (HP:0007375)2.44302491
60Congenital ichthyosiform erythroderma (HP:0007431)2.37353577
61Split foot (HP:0001839)2.34819861
62Urinary urgency (HP:0000012)2.32877398
63Postural instability (HP:0002172)2.31297473
64Autoamputation (HP:0001218)2.28974611
65Amyotrophic lateral sclerosis (HP:0007354)2.28930890
66Lower limb muscle weakness (HP:0007340)2.28030309
67Clumsiness (HP:0002312)2.26789929
68Poor speech (HP:0002465)2.25813103
69Cerebral hemorrhage (HP:0001342)2.24526152
70Epileptiform EEG discharges (HP:0011182)2.24137769
71Premature skin wrinkling (HP:0100678)2.24100853
72Abnormality of the labia minora (HP:0012880)2.23612712
73Abnormality of the lower motor neuron (HP:0002366)2.22322864
74Abnormal social behavior (HP:0012433)2.18286049
75Impaired social interactions (HP:0000735)2.18286049
76Megalencephaly (HP:0001355)2.17914907
77Adrenal hypoplasia (HP:0000835)2.17381842
78Cupped ear (HP:0000378)2.14905061
79Stridor (HP:0010307)2.14317457
80Morphological abnormality of the pyramidal tract (HP:0002062)2.10336608
81Increased circulating renin level (HP:0000848)2.09338856
82Aplasia involving bones of the upper limbs (HP:0009823)2.06922933
83Aplasia of the phalanges of the hand (HP:0009802)2.06922933
84Aplasia involving bones of the extremities (HP:0009825)2.06922933
85Action tremor (HP:0002345)2.06684278
86Atonic seizures (HP:0010819)2.06613010
87Clonus (HP:0002169)2.04867602
88Abnormality of glycolysis (HP:0004366)2.02309507
89Increased serum pyruvate (HP:0003542)2.02309507
90Bowel incontinence (HP:0002607)2.02280913
91EEG with generalized epileptiform discharges (HP:0011198)2.01539143
92Abnormality of cochlea (HP:0000375)1.99319644
93Abnormality of the phalanges of the 2nd finger (HP:0009541)1.98947466
94Partial agenesis of the corpus callosum (HP:0001338)1.98746104
95Sleep apnea (HP:0010535)1.97902620
96Cutaneous finger syndactyly (HP:0010554)1.97770332
97Impaired smooth pursuit (HP:0007772)1.97524859
98Decreased motor nerve conduction velocity (HP:0003431)1.97259848
99Spastic paraplegia (HP:0001258)1.96776372
100Paraplegia (HP:0010550)1.96678132
101Paraparesis (HP:0002385)1.95828242
102Depression (HP:0000716)1.95535227
103Foot dorsiflexor weakness (HP:0009027)1.94900138
104Hypsarrhythmia (HP:0002521)1.94871524
105Generalized myoclonic seizures (HP:0002123)1.94512200
106Urinary incontinence (HP:0000020)1.94229613
107Neuronal loss in central nervous system (HP:0002529)1.93769164
108Impaired vibratory sensation (HP:0002495)1.92544115
109Hepatoblastoma (HP:0002884)1.92258148
110Broad-based gait (HP:0002136)1.91944081
111Hypoplasia of the corpus callosum (HP:0002079)1.91912643
112Vaginal atresia (HP:0000148)1.91236765
113Metabolic alkalosis (HP:0200114)1.91077478
114Abnormal large intestine physiology (HP:0012700)1.90704143
115Pheochromocytoma (HP:0002666)1.90422226
116Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.89407401
117Progressive inability to walk (HP:0002505)1.88611106
118Esophageal atresia (HP:0002032)1.88585934
119Hypoplasia of the iris (HP:0007676)1.87652061
120Aqueductal stenosis (HP:0002410)1.87452281
121Gowers sign (HP:0003391)1.87285679
122Choreoathetosis (HP:0001266)1.86408475
123Gaze-evoked nystagmus (HP:0000640)1.85674133
124Mutism (HP:0002300)1.85637057
125Oligodactyly (hands) (HP:0001180)1.85133581
126Genital tract atresia (HP:0001827)1.85125628
127Hypomagnesemia (HP:0002917)1.85040955
128Abnormality of ocular smooth pursuit (HP:0000617)1.84893619
129Urinary bladder sphincter dysfunction (HP:0002839)1.84068553
130Muscle fiber splitting (HP:0003555)1.83984746
131Torticollis (HP:0000473)1.83588969
132Papilledema (HP:0001085)1.81535506
133Insomnia (HP:0100785)1.80688218
134Protruding tongue (HP:0010808)1.80389173
135Abnormality of the foot musculature (HP:0001436)1.79796136
136Hammertoe (HP:0001765)1.79361076
137Intestinal atresia (HP:0011100)1.78774397
138White forelock (HP:0002211)1.77941446
139Status epilepticus (HP:0002133)1.77401281
140Widely spaced teeth (HP:0000687)1.77321309
141Obstructive sleep apnea (HP:0002870)1.77256703
142Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.76884642
143Postnatal microcephaly (HP:0005484)1.76632902
144Visual hallucinations (HP:0002367)1.76582918
145Limb dystonia (HP:0002451)1.76435586
146Coronal craniosynostosis (HP:0004440)1.75968176
147Turricephaly (HP:0000262)1.75706280
148Anxiety (HP:0000739)1.75314573
149Stereotypic behavior (HP:0000733)1.75073561
150Patchy hypopigmentation of hair (HP:0011365)1.74246611
151Genetic anticipation (HP:0003743)1.73925808
152Cutaneous syndactyly (HP:0012725)1.73856701
153Distal sensory impairment (HP:0002936)1.72919759
154Bradykinesia (HP:0002067)1.72183717
155Decreased number of peripheral myelinated nerve fibers (HP:0003380)1.71223053
156Axonal loss (HP:0003447)1.69045226
157Humeroradial synostosis (HP:0003041)1.68936933
158Synostosis involving the elbow (HP:0003938)1.68936933
159Type II lissencephaly (HP:0007260)1.68076708
160Anomalous pulmonary venous return (HP:0010772)1.67680296

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK395.70998573
2OXSR14.13052143
3EPHB12.69283912
4MAPKAPK52.65799596
5BCR2.54291706
6PKN12.52491220
7CDK192.39718256
8FGFR22.10400005
9WNK42.04127267
10CSNK1G32.03928668
11CSNK1A1L1.92214864
12TESK21.88190850
13UHMK11.81663842
14PBK1.80077307
15PAK61.79311198
16CSNK1G11.77684245
17DYRK21.77613356
18PNCK1.76374398
19WNK11.73427300
20DAPK21.72676724
21LIMK11.71908626
22MINK11.69591658
23CSNK1G21.66909448
24CAMKK11.65348098
25MET1.63534384
26KSR21.62422390
27PRPF4B1.62042138
28MARK11.56726698
29NEK61.51249036
30CAMK2B1.46930828
31SGK21.44738746
32SGK2231.44128301
33SGK4941.44128301
34EPHA41.42856430
35TNIK1.42363759
36FGR1.41155421
37TYRO31.41045483
38NTRK11.34979976
39ROCK21.34958650
40ICK1.31872536
41MAP3K131.26552197
42MAP3K91.22345158
43SIK21.20247835
44CLK11.20174597
45MARK21.15090808
46PLK21.14825221
47PRKCG1.11714486
48ARAF1.09071482
49PINK11.05667311
50CCNB11.03713690
51SGK11.03604459
52CAMK2D1.03552332
53MUSK1.02141703
54BMPR21.01760193
55CASK0.99101575
56PRKD30.98408221
57MAP2K40.97821589
58CDK140.93336708
59ERBB40.91083080
60CDK150.90437256
61MOS0.89929052
62SGK30.88525536
63CAMK2G0.87324619
64CDK50.87309933
65ALK0.86508172
66CAMK2A0.86072739
67MST40.85303497
68CDK180.84602002
69CDK11A0.81884855
70MAPK130.80944206
71PAK30.79693179
72CAMKK20.79606471
73PRKCQ0.78629185
74NTRK20.76815740
75DMPK0.75149954
76EPHA30.74455133
77MKNK20.73183009
78BMPR1B0.71075168
79CAMK10.69028184
80PRKD10.68760152
81PHKG20.66404549
82PHKG10.66404549
83CAMK40.65592891
84RPS6KA30.65085020
85BRD40.63398322
86PRKCZ0.62933631
87HIPK20.62425849
88DYRK1A0.62154007
89MAP3K40.61720918
90STK110.61695529
91MAP3K60.60473086
92RAF10.57790075
93CSNK1D0.55813669
94PDPK10.54908384
95PRKCH0.54540371
96WNK30.54113046
97RET0.54019920
98MAPK120.52546772
99RPS6KA50.52291797
100MELK0.49792727
101PRKDC0.48429514
102PRKD20.48059814
103FYN0.44652362
104CSNK1E0.44604722
105LATS20.44572360
106DAPK10.44041863
107CSNK1A10.43946248
108GSK3B0.43547711
109PRKCE0.42192044
110STK38L0.40529913
111FGFR30.39992026
112PRKG10.39815221
113KSR10.39507516
114ITK0.38920613
115YES10.38572565
116MAPK150.38525260
117LATS10.38312853
118RPS6KB10.37963810
119CDK30.37097644
120MAP2K70.36932700
121PAK10.36239840
122BRSK10.36053851
123MAPK100.35934893
124NTRK30.34179323
125CAMK1G0.33513143
126PRKCB0.33322190
127PRKACB0.32823503
128PDGFRB0.32510488
129FES0.31674387
130GSK3A0.31327441
131ABL20.30407174
132ERBB20.30303378
133PDK10.30059483
134TAOK30.29142664
135MKNK10.28614795

Predicted pathways (KEGG)

RankGene SetZ-score
1Terpenoid backbone biosynthesis_Homo sapiens_hsa009005.07587575
2Steroid biosynthesis_Homo sapiens_hsa001004.14406472
3Fatty acid elongation_Homo sapiens_hsa000623.77954329
4Ether lipid metabolism_Homo sapiens_hsa005653.27583879
5Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.04244859
6Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.95909015
7Vitamin B6 metabolism_Homo sapiens_hsa007502.22003254
8Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.17565042
9Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.02297457
10Sphingolipid metabolism_Homo sapiens_hsa006001.83211064
11Axon guidance_Homo sapiens_hsa043601.82769217
12Linoleic acid metabolism_Homo sapiens_hsa005911.73406033
13Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.70120254
14Protein export_Homo sapiens_hsa030601.69697369
15Glutamatergic synapse_Homo sapiens_hsa047241.68843512
16GABAergic synapse_Homo sapiens_hsa047271.59588829
17Serotonergic synapse_Homo sapiens_hsa047261.54245367
18alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.53924604
19Renal cell carcinoma_Homo sapiens_hsa052111.52544412
20Long-term depression_Homo sapiens_hsa047301.50539477
21Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.49784824
22Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.41888382
23Morphine addiction_Homo sapiens_hsa050321.37554149
24Sulfur metabolism_Homo sapiens_hsa009201.37546750
25Estrogen signaling pathway_Homo sapiens_hsa049151.30996365
26Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.28297474
27Sphingolipid signaling pathway_Homo sapiens_hsa040711.22353779
28Glioma_Homo sapiens_hsa052141.21483539
29Oxidative phosphorylation_Homo sapiens_hsa001901.19551809
30Nicotine addiction_Homo sapiens_hsa050331.19485501
31Cocaine addiction_Homo sapiens_hsa050301.18849134
32Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.18536467
33Histidine metabolism_Homo sapiens_hsa003401.18024270
34Nitrogen metabolism_Homo sapiens_hsa009101.11684781
35Dopaminergic synapse_Homo sapiens_hsa047281.06525911
36Circadian entrainment_Homo sapiens_hsa047131.05442316
37beta-Alanine metabolism_Homo sapiens_hsa004101.03638931
38Ovarian steroidogenesis_Homo sapiens_hsa049131.03475434
39Dorso-ventral axis formation_Homo sapiens_hsa043201.03016984
40cGMP-PKG signaling pathway_Homo sapiens_hsa040221.01481757
41SNARE interactions in vesicular transport_Homo sapiens_hsa041301.01314142
42Butanoate metabolism_Homo sapiens_hsa006500.97989450
43Bile secretion_Homo sapiens_hsa049760.96063603
44Tight junction_Homo sapiens_hsa045300.95522628
45Ras signaling pathway_Homo sapiens_hsa040140.93166433
46Endocytosis_Homo sapiens_hsa041440.92712502
47Phospholipase D signaling pathway_Homo sapiens_hsa040720.92411947
48Alzheimers disease_Homo sapiens_hsa050100.91166480
49Type II diabetes mellitus_Homo sapiens_hsa049300.90638505
50ErbB signaling pathway_Homo sapiens_hsa040120.89300028
51Rap1 signaling pathway_Homo sapiens_hsa040150.88609540
52Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.88217711
53Thyroid hormone signaling pathway_Homo sapiens_hsa049190.86287372
54Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.86067436
55Cholinergic synapse_Homo sapiens_hsa047250.85957402
56Glycerophospholipid metabolism_Homo sapiens_hsa005640.85821108
57Salivary secretion_Homo sapiens_hsa049700.84943453
58Neurotrophin signaling pathway_Homo sapiens_hsa047220.84917633
59Vascular smooth muscle contraction_Homo sapiens_hsa042700.83744924
60Circadian rhythm_Homo sapiens_hsa047100.83367785
61Parkinsons disease_Homo sapiens_hsa050120.82693218
62Long-term potentiation_Homo sapiens_hsa047200.82398889
63Gastric acid secretion_Homo sapiens_hsa049710.82151803
64Thyroid hormone synthesis_Homo sapiens_hsa049180.81262426
65Endometrial cancer_Homo sapiens_hsa052130.80888453
66Choline metabolism in cancer_Homo sapiens_hsa052310.80635454
67Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.79977851
68Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.79696648
69Amphetamine addiction_Homo sapiens_hsa050310.78773300
70Basal transcription factors_Homo sapiens_hsa030220.75460739
71Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.75391482
72Synaptic vesicle cycle_Homo sapiens_hsa047210.74556263
73Arginine and proline metabolism_Homo sapiens_hsa003300.74272298
74Autoimmune thyroid disease_Homo sapiens_hsa053200.74054707
75Gap junction_Homo sapiens_hsa045400.71588178
76Colorectal cancer_Homo sapiens_hsa052100.70549789
77Carbohydrate digestion and absorption_Homo sapiens_hsa049730.69825589
78Collecting duct acid secretion_Homo sapiens_hsa049660.68574705
79Vibrio cholerae infection_Homo sapiens_hsa051100.67652867
80Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.66703419
81Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.64971541
82Prion diseases_Homo sapiens_hsa050200.64866102
83Phototransduction_Homo sapiens_hsa047440.64752117
84Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.64685508
85cAMP signaling pathway_Homo sapiens_hsa040240.63209036
86Pancreatic secretion_Homo sapiens_hsa049720.60136194
87Hippo signaling pathway_Homo sapiens_hsa043900.60029285
88MAPK signaling pathway_Homo sapiens_hsa040100.59317178
89mTOR signaling pathway_Homo sapiens_hsa041500.58857206
90Olfactory transduction_Homo sapiens_hsa047400.58642582
91Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.58514550
92Renin secretion_Homo sapiens_hsa049240.58263120
93Longevity regulating pathway - mammal_Homo sapiens_hsa042110.57457637
94Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.57064411
95Folate biosynthesis_Homo sapiens_hsa007900.55983103
96Hedgehog signaling pathway_Homo sapiens_hsa043400.55939114
97Taste transduction_Homo sapiens_hsa047420.54242300
98Regulation of actin cytoskeleton_Homo sapiens_hsa048100.51782609
99Phosphatidylinositol signaling system_Homo sapiens_hsa040700.51570376
100GnRH signaling pathway_Homo sapiens_hsa049120.51304505
101Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.50983244
102Arachidonic acid metabolism_Homo sapiens_hsa005900.50594290
103Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.49601133
104Rheumatoid arthritis_Homo sapiens_hsa053230.49035309
105Chemokine signaling pathway_Homo sapiens_hsa040620.47610938
106Wnt signaling pathway_Homo sapiens_hsa043100.46981768
107mRNA surveillance pathway_Homo sapiens_hsa030150.46599998
108VEGF signaling pathway_Homo sapiens_hsa043700.45329578
109Oocyte meiosis_Homo sapiens_hsa041140.45106140
110T cell receptor signaling pathway_Homo sapiens_hsa046600.44476520
111Cardiac muscle contraction_Homo sapiens_hsa042600.42911695
112Alcoholism_Homo sapiens_hsa050340.42146472
113Oxytocin signaling pathway_Homo sapiens_hsa049210.41743380
114Huntingtons disease_Homo sapiens_hsa050160.40645176
115Glucagon signaling pathway_Homo sapiens_hsa049220.39151971
116Inositol phosphate metabolism_Homo sapiens_hsa005620.38838866
117Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.38577511
118Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.38561244
119Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.36486621
120AMPK signaling pathway_Homo sapiens_hsa041520.36200963
121Insulin secretion_Homo sapiens_hsa049110.36021294
122Melanogenesis_Homo sapiens_hsa049160.35798675
123Non-small cell lung cancer_Homo sapiens_hsa052230.35556476
124Mineral absorption_Homo sapiens_hsa049780.35186703
125Regulation of autophagy_Homo sapiens_hsa041400.30873927
126Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.30011294
127Glutathione metabolism_Homo sapiens_hsa004800.29454511
128Prolactin signaling pathway_Homo sapiens_hsa049170.29203518
129Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.28837764
130Calcium signaling pathway_Homo sapiens_hsa040200.28632450
131Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.27676247
132Aldosterone synthesis and secretion_Homo sapiens_hsa049250.27471075
133Melanoma_Homo sapiens_hsa052180.25991852
134Lysine degradation_Homo sapiens_hsa003100.25301649
135MicroRNAs in cancer_Homo sapiens_hsa052060.24139375

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