SLC13A2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is a sodium-coupled citrate transporter that is regulated by the chaperone activity of cyclophilin b. The encoded protein may play a role in the formation of kidney stones. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1intestinal absorption (GO:0050892)8.08789579
2angiotensin maturation (GO:0002003)7.78032578
3intestinal cholesterol absorption (GO:0030299)7.20449865
4epoxygenase P450 pathway (GO:0019373)7.07246754
5fat-soluble vitamin biosynthetic process (GO:0042362)6.92653809
6modified amino acid transport (GO:0072337)6.52900552
7vitamin transmembrane transport (GO:0035461)6.30461492
8positive regulation of guanylate cyclase activity (GO:0031284)5.78272394
9drug catabolic process (GO:0042737)5.72940820
10flavonoid metabolic process (GO:0009812)5.56190800
11bile acid and bile salt transport (GO:0015721)5.41990033
12regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044)5.41842918
13endocrine process (GO:0050886)5.41842918
14regulation of systemic arterial blood pressure by hormone (GO:0001990)5.41842918
15regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)5.31623287
16drug transmembrane transport (GO:0006855)5.18752854
17drug transport (GO:0015893)5.12368965
18UDP-N-acetylglucosamine metabolic process (GO:0006047)5.10141060
19sulfur compound transport (GO:0072348)5.00160626
20very-low-density lipoprotein particle assembly (GO:0034379)4.96793512
21regulation of bile acid biosynthetic process (GO:0070857)4.95667347
22urate metabolic process (GO:0046415)4.89206640
23regulation of systemic arterial blood pressure (GO:0003073)4.87116145
24diacylglycerol metabolic process (GO:0046339)4.78244903
25renal system process involved in regulation of blood volume (GO:0001977)4.75127133
26vitamin transport (GO:0051180)4.69702476
27regulation of cGMP biosynthetic process (GO:0030826)4.65426152
28vitamin A metabolic process (GO:0006776)4.58487002
29urea cycle (GO:0000050)4.57519388
30intestinal epithelial cell development (GO:0060576)4.55659170
31receptor guanylyl cyclase signaling pathway (GO:0007168)4.46823181
323-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)4.43398601
33purine ribonucleoside bisphosphate metabolic process (GO:0034035)4.43398601
34actin filament depolymerization (GO:0030042)4.42321080
35cysteine metabolic process (GO:0006534)4.41835365
36urea metabolic process (GO:0019627)4.38989046
37peptide hormone processing (GO:0016486)4.38757644
38homocysteine metabolic process (GO:0050667)4.34466840
39sulfur amino acid catabolic process (GO:0000098)4.33348120
40sulfate transmembrane transport (GO:1902358)4.30046745
41NADH metabolic process (GO:0006734)4.27742980
42cellular response to nitric oxide (GO:0071732)4.27549023
43exogenous drug catabolic process (GO:0042738)4.22547540
44protein-lipid complex assembly (GO:0065005)4.15035952
45regulation of cellular extravasation (GO:0002691)4.13864870
46maintenance of gastrointestinal epithelium (GO:0030277)4.08397865
47renal absorption (GO:0070293)4.07805880
48adhesion of symbiont to host cell (GO:0044650)4.07735033
49virion attachment to host cell (GO:0019062)4.07735033
50regulation of cholesterol homeostasis (GO:2000188)4.06741551
51oligosaccharide catabolic process (GO:0009313)4.05786620
52nitrogen cycle metabolic process (GO:0071941)4.02516149
53peptide catabolic process (GO:0043171)3.96124582
54bundle of His cell to Purkinje myocyte communication (GO:0086069)3.90141608
55fructose metabolic process (GO:0006000)3.89404006
56digestive system process (GO:0022600)3.88428282
57regulation of cGMP metabolic process (GO:0030823)3.84685771
58pantothenate metabolic process (GO:0015939)3.82145053
59lysine catabolic process (GO:0006554)3.82050266
60lysine metabolic process (GO:0006553)3.82050266
61regulation of vitamin metabolic process (GO:0030656)3.80167107
62glucose 6-phosphate metabolic process (GO:0051156)3.78122858
63glycolipid catabolic process (GO:0019377)3.76447160
64alkaloid metabolic process (GO:0009820)3.75152957
65positive regulation of lipoprotein lipase activity (GO:0051006)3.74663972
66positive regulation of triglyceride lipase activity (GO:0061365)3.74663972
67glycosphingolipid catabolic process (GO:0046479)3.70760788
68pyrimidine-containing compound transmembrane transport (GO:0072531)3.70716891
69negative regulation of cholesterol transport (GO:0032375)3.68673977
70negative regulation of sterol transport (GO:0032372)3.68673977
71sulfate transport (GO:0008272)3.66960829
72hormone catabolic process (GO:0042447)3.64496065
73regulation of guanylate cyclase activity (GO:0031282)3.61258572
74cellular response to reactive nitrogen species (GO:1902170)3.61187671
75drinking behavior (GO:0042756)3.60779359
76fat-soluble vitamin metabolic process (GO:0006775)3.60491835
77triglyceride-rich lipoprotein particle remodeling (GO:0034370)3.60155849
78response to nitric oxide (GO:0071731)3.59968268
79folic acid transport (GO:0015884)3.57535953
80antibacterial humoral response (GO:0019731)3.55996824
81regulation of triglyceride catabolic process (GO:0010896)3.53462439
82phospholipid efflux (GO:0033700)3.51899870
83phosphate ion transport (GO:0006817)3.51136868
84glutamine family amino acid biosynthetic process (GO:0009084)3.50309123
85renal system process involved in regulation of systemic arterial blood pressure (GO:0003071)3.50168569
86positive regulation of pseudopodium assembly (GO:0031274)3.49450275
87antimicrobial humoral response (GO:0019730)3.49306490
88phosphate ion transmembrane transport (GO:0035435)3.47101468
89glutathione biosynthetic process (GO:0006750)3.46693560
90serine family amino acid catabolic process (GO:0009071)3.46598623
91nonribosomal peptide biosynthetic process (GO:0019184)3.46129488
92bicarbonate transport (GO:0015701)3.43945758
93sterol homeostasis (GO:0055092)3.43900456
94vitamin biosynthetic process (GO:0009110)3.43665638
95cholesterol homeostasis (GO:0042632)3.43182389
96drug metabolic process (GO:0017144)3.43075891
97cGMP-mediated signaling (GO:0019934)3.40096248
98positive regulation of cGMP biosynthetic process (GO:0030828)3.38033391
99cGMP biosynthetic process (GO:0006182)3.37915313
100lipoprotein metabolic process (GO:0042157)3.37586392
101phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)3.34727798
102glycosylceramide metabolic process (GO:0006677)3.33370076
103folic acid metabolic process (GO:0046655)3.33327496
104positive regulation of lipid catabolic process (GO:0050996)3.33309513
105proline metabolic process (GO:0006560)3.33052069
106cellular glucuronidation (GO:0052695)3.30167728
107alditol metabolic process (GO:0019400)3.28464154
108response to hydroperoxide (GO:0033194)3.28123018
109digestion (GO:0007586)3.27700632
110organic cation transport (GO:0015695)3.26904599
111regulation of cholesterol esterification (GO:0010872)3.26792704
112calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)3.26783572
113amino-acid betaine metabolic process (GO:0006577)3.24021666
114sexual reproduction (GO:0019953)3.23534628
115CDP-diacylglycerol metabolic process (GO:0046341)3.22683489
116cobalamin metabolic process (GO:0009235)3.22681193
117purine nucleobase biosynthetic process (GO:0009113)3.22274297
118excretion (GO:0007588)3.22257467
119bile acid metabolic process (GO:0008206)3.21329946
120adhesion of symbiont to host (GO:0044406)3.21223280
121high-density lipoprotein particle remodeling (GO:0034375)3.20664946
122positive regulation of glycoprotein biosynthetic process (GO:0010560)3.20422950
123L-ascorbic acid metabolic process (GO:0019852)3.19049009
124leukotriene metabolic process (GO:0006691)3.17317919
125sodium ion homeostasis (GO:0055078)3.13525280
126transepithelial transport (GO:0070633)3.13324946
127sphingomyelin metabolic process (GO:0006684)3.13267290
128regulation of pseudopodium assembly (GO:0031272)3.11647812
129ceramide catabolic process (GO:0046514)3.11474360
130indole-containing compound catabolic process (GO:0042436)3.11409025
131indolalkylamine catabolic process (GO:0046218)3.11409025
132tryptophan catabolic process (GO:0006569)3.11409025
133nucleoside diphosphate biosynthetic process (GO:0009133)3.11405368
134plasma lipoprotein particle assembly (GO:0034377)3.09970751
135proline biosynthetic process (GO:0006561)3.09642411
136arginine metabolic process (GO:0006525)3.07253740
137epithelial structure maintenance (GO:0010669)3.05992398
138serine family amino acid metabolic process (GO:0009069)3.05420367
139phosphatidylcholine biosynthetic process (GO:0006656)3.04720782
140nucleotide-sugar biosynthetic process (GO:0009226)3.04336083
141glucuronate metabolic process (GO:0019585)3.03970376
142uronic acid metabolic process (GO:0006063)3.03970376
143heme transport (GO:0015886)3.01963294
144amino acid transmembrane transport (GO:0003333)3.00081339
145fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)2.99513201
146lipoprotein transport (GO:0042953)2.98940702
147sulfation (GO:0051923)2.98864773
148monocarboxylic acid transport (GO:0015718)2.96520559
149transcytosis (GO:0045056)2.95879605
150response to hepatocyte growth factor (GO:0035728)2.95762694
151cellular response to hepatocyte growth factor stimulus (GO:0035729)2.95762694
152quaternary ammonium group transport (GO:0015697)2.94600180
153glycerol metabolic process (GO:0006071)2.93543448
154polyol transport (GO:0015791)2.92470841

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human5.82651488
2ESR1_17901129_ChIP-ChIP_LIVER_Mouse5.04155822
3CDX2_20551321_ChIP-Seq_CACO-2_Human4.19988397
4* PPARA_22158963_ChIP-Seq_LIVER_Mouse3.96594948
5* RXR_22158963_ChIP-Seq_LIVER_Mouse3.95224862
6PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.49659637
7HNF4A_19761587_ChIP-ChIP_CACO-2_Human3.42080395
8SOX2_27498859_Chip-Seq_STOMACH_Mouse3.28515720
9LXR_22158963_ChIP-Seq_LIVER_Mouse3.16280716
10BP1_19119308_ChIP-ChIP_Hs578T_Human2.92150904
11TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.78555125
12* GATA4_25053715_ChIP-Seq_YYC3_Human2.76972871
13AR_21909140_ChIP-Seq_LNCAP_Human2.58367648
14STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse2.54954943
15EGR1_23403033_ChIP-Seq_LIVER_Mouse2.53697648
16* GATA6_25053715_ChIP-Seq_YYC3_Human2.52105368
17* NR0B1_18358816_ChIP-ChIP_MESCs_Mouse2.47559877
18ESR2_21235772_ChIP-Seq_MCF-7_Human2.22514096
19GATA1_22025678_ChIP-Seq_K562_Human2.18378161
20SOX2_20726797_ChIP-Seq_SW620_Human2.12799759
21ESR1_21235772_ChIP-Seq_MCF-7_Human2.11804759
22CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human2.09772705
23ZNF263_19887448_ChIP-Seq_K562_Human2.08457065
24CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.98149255
25IRF8_22096565_ChIP-ChIP_GC-B_Human1.97763333
26CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.91905098
27SRY_22984422_ChIP-ChIP_TESTIS_Rat1.91626752
28NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.76888555
29FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.74577030
30PPAR_26484153_Chip-Seq_NCI-H1993_Human1.73134995
31* RACK7_27058665_Chip-Seq_MCF-7_Human1.70484773
32* PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.69829137
33CLOCK_20551151_ChIP-Seq_293T_Human1.68638905
34BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.66841760
35* KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.63989667
36ATF3_27146783_Chip-Seq_COLON_Human1.61736754
37CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.61411015
38IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.56513403
39SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.54631308
40STAT3_1855785_ChIP-Seq_MESCs_Mouse1.52193233
41ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.51142793
42KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.50920522
43NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.49242788
44RUNX1_27514584_Chip-Seq_MCF-7_Human1.46273615
45RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.44074725
46HNF4A_19822575_ChIP-Seq_HepG2_Human1.43911624
47KAP1_22055183_ChIP-Seq_ESCs_Mouse1.42870374
48CDX2_19796622_ChIP-Seq_MESCs_Mouse1.41315996
49TRIM28_21343339_ChIP-Seq_HEK293_Human1.39777001
50POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.36318253
51KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.36238856
52FOXO3_23340844_ChIP-Seq_DLD1_Human1.34933021
53BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.30284930
54CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.30264848
55SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.29297687
56NANOG_18555785_ChIP-Seq_MESCs_Mouse1.28833982
57TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.27355755
58TCF3_18692474_ChIP-Seq_MEFs_Mouse1.27347571
59KLF5_25053715_ChIP-Seq_YYC3_Human1.25526027
60SA1_27219007_Chip-Seq_Bcells_Human1.24953836
61E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.24888225
62PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.23486788
63ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.22198614
64CTCF_27219007_Chip-Seq_Bcells_Human1.21777434
65TCF4_18268006_ChIP-ChIP_LS174T_Human1.21194505
66SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.20832791
67RARG_19884340_ChIP-ChIP_MEFs_Mouse1.20017821
68JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse1.15457094
69CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.12918332
70* SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.12662903
71CREB1_26743006_Chip-Seq_LNCaP_Human1.10000087
72SREBP2_21459322_ChIP-Seq_LIVER_Mouse1.09194877
73GATA1_19941826_ChIP-Seq_K562_Human1.08075292
74BCOR_27268052_Chip-Seq_Bcells_Human1.08054345
75* OCT4_18692474_ChIP-Seq_MEFs_Mouse1.08038618
76* NANOG_18692474_ChIP-Seq_MEFs_Mouse1.07354793
77CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.06847240
78* FOXA1_25552417_ChIP-Seq_VCAP_Human1.04736493
79THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.04562233
80FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.04548176
81SALL4_18804426_ChIP-ChIP_XEN_Mouse1.03655412
82* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.02899043
83GATA2_19941826_ChIP-Seq_K562_Human1.02198543
84ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.01824976
85SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.01255001
86* TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.00767229
87ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.00444022
88VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.99689249
89RXR_22108803_ChIP-Seq_LS180_Human0.99572958
90ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.99166483
91TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.99151235
92RARA_24833708_ChIP-Seq_LIVER_Mouse0.98140950
93EGR1_19032775_ChIP-ChIP_M12_Human0.97811734
94DNAJC2_21179169_ChIP-ChIP_NT2_Human0.97468439
95NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.97026028
96* NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.96793450
97CDX2_22108803_ChIP-Seq_LS180_Human0.96786430
98LXR_22292898_ChIP-Seq_THP-1_Human0.94778841
99EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.94745862
100IRF8_21731497_ChIP-ChIP_J774_Mouse0.94071376
101KAP1_27257070_Chip-Seq_ESCs_Mouse0.93690220
102TCF7L2_21901280_ChIP-Seq_H4IIE_Rat0.93057664
103NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.92302309
104PHF8_20622854_ChIP-Seq_HELA_Human0.92087449
105* SOX2_18692474_ChIP-Seq_MEFs_Mouse0.91325476
106TAF2_19829295_ChIP-Seq_ESCs_Human0.91180373
107FOXA2_19822575_ChIP-Seq_HepG2_Human0.90977171
108BCL6_27268052_Chip-Seq_Bcells_Human0.90382766
109* TP63_22573176_ChIP-Seq_HFKS_Human0.90325437
110CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.89036584
111P68_20966046_ChIP-Seq_HELA_Human0.88998113
112TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.88723527
113FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.88263307
114* RAD21_21589869_ChIP-Seq_MESCs_Mouse0.87678183
115MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.87644347
116AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.86895983
117NANOG_20526341_ChIP-Seq_ESCs_Human0.86873574
118RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.86865626
119CEBPB_22108803_ChIP-Seq_LS180_Human0.85732343
120TET1_21451524_ChIP-Seq_MESCs_Mouse0.85001332
121VDR_24763502_ChIP-Seq_THP-1_Human0.84895263
122SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.84855447
123UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.83680934
124PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.83215896
125TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.83044685
126P63_26484246_Chip-Seq_KERATINOCYTES_Human0.82329927
127GATA3_24758297_ChIP-Seq_MCF-7_Human0.82055639
128VDR_24787735_ChIP-Seq_THP-1_Human0.81319594
129* NANOG_18692474_ChIP-Seq_MESCs_Mouse0.80602456
130VDR_22108803_ChIP-Seq_LS180_Human0.79663143
131CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.79649819
132STAT1_20625510_ChIP-Seq_HELA_Human0.79490882
133CTCF_27219007_Chip-Seq_ERYTHROID_Human0.79384746
134MYC_19915707_ChIP-ChIP_AK7_Human0.78461422
135* GATA2_22383799_ChIP-Seq_G1ME_Mouse0.77820934
136GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.77188984
137EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.76099040
138ETS1_21867929_ChIP-Seq_TH2_Mouse0.75760614
139ERG_21242973_ChIP-ChIP_JURKAT_Human0.75224837

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005360_urolithiasis8.30349424
2MP0010234_abnormal_vibrissa_follicle4.41928448
3MP0001666_abnormal_nutrient_absorption4.28512652
4MP0002139_abnormal_hepatobiliary_system4.13759558
5MP0003878_abnormal_ear_physiology3.73347853
6MP0005377_hearing/vestibular/ear_phenot3.73347853
7MP0009379_abnormal_foot_pigmentation3.65788296
8MP0009840_abnormal_foam_cell3.47168822
9MP0008875_abnormal_xenobiotic_pharmacok3.43922156
10MP0005085_abnormal_gallbladder_physiolo3.32056606
11MP0004264_abnormal_extraembryonic_tissu3.27676831
12MP0004019_abnormal_vitamin_homeostasis3.19024864
13MP0005365_abnormal_bile_salt2.72056349
14MP0004043_abnormal_pH_regulation2.65488687
15MP0003252_abnormal_bile_duct2.58045156
16MP0005332_abnormal_amino_acid2.53069856
17MP0003866_abnormal_defecation2.45696282
18MP0005409_darkened_coat_color2.18834888
19MP0010329_abnormal_lipoprotein_level2.16169519
20* MP0009643_abnormal_urine_homeostasis2.13556845
21MP0002822_catalepsy2.06296552
22MP0000462_abnormal_digestive_system2.01504854
23MP0003191_abnormal_cellular_cholesterol1.81430664
24MP0005670_abnormal_white_adipose1.79506763
25MP0001765_abnormal_ion_homeostasis1.77933306
26MP0000538_abnormal_urinary_bladder1.69210031
27MP0001873_stomach_inflammation1.68719736
28MP0005636_abnormal_mineral_homeostasis1.65423070
29MP0003183_abnormal_peptide_metabolism1.63970151
30MP0001756_abnormal_urination1.63948825
31MP0003806_abnormal_nucleotide_metabolis1.62338524
32MP0001663_abnormal_digestive_system1.62047329
33MP0005451_abnormal_body_composition1.59033030
34MP0010155_abnormal_intestine_physiology1.58704221
35MP0005381_digestive/alimentary_phenotyp1.54043330
36MP0005084_abnormal_gallbladder_morpholo1.52217143
37MP0000678_abnormal_parathyroid_gland1.49971951
38MP0010352_gastrointestinal_tract_polyps1.48547463
39MP0003718_maternal_effect1.47787733
40MP0004147_increased_porphyrin_level1.47378496
41MP0002876_abnormal_thyroid_physiology1.45364045
42MP0002136_abnormal_kidney_physiology1.42350193
43MP0000490_abnormal_crypts_of1.42265027
44MP0003693_abnormal_embryo_hatching1.41205246
45MP0000477_abnormal_intestine_morphology1.41148431
46MP0000537_abnormal_urethra_morphology1.38126798
47MP0002796_impaired_skin_barrier1.37521616
48MP0001188_hyperpigmentation1.36759964
49MP0003705_abnormal_hypodermis_morpholog1.34960406
50MP0001664_abnormal_digestion1.32628295
51MP0002254_reproductive_system_inflammat1.29112342
52MP0005319_abnormal_enzyme/_coenzyme1.23251012
53MP0005058_abnormal_lysosome_morphology1.22837342
54MP0005167_abnormal_blood-brain_barrier1.22509596
55MP0002118_abnormal_lipid_homeostasis1.17239217
56MP0000609_abnormal_liver_physiology1.15033774
57MP0002138_abnormal_hepatobiliary_system1.14272385
58MP0001764_abnormal_homeostasis1.08605808
59MP0003283_abnormal_digestive_organ1.07077310
60MP0003879_abnormal_hair_cell1.05515344
61MP0005310_abnormal_salivary_gland1.03813099
62MP0003315_abnormal_perineum_morphology1.02211454
63MP0004858_abnormal_nervous_system0.98322973
64MP0002971_abnormal_brown_adipose0.97467734
65MP0010678_abnormal_skin_adnexa0.97035637
66MP0004270_analgesia0.96613976
67MP0003300_gastrointestinal_ulcer0.96547462
68MP0005535_abnormal_body_temperature0.95371880
69MP0001501_abnormal_sleep_pattern0.92541235
70MP0001849_ear_inflammation0.89000506
71MP0000566_synostosis0.86333056
72MP0005584_abnormal_enzyme/coenzyme_acti0.80812274
73MP0003195_calcinosis0.79589209
74MP0009115_abnormal_fat_cell0.78082085
75MP0002098_abnormal_vibrissa_morphology0.77619605
76MP0005666_abnormal_adipose_tissue0.76258513
77MP0005501_abnormal_skin_physiology0.75793003
78MP0004947_skin_inflammation0.74798127
79MP0001881_abnormal_mammary_gland0.72701893
80MP0002089_abnormal_postnatal_growth/wei0.72389518
81MP0004885_abnormal_endolymph0.71944783
82MP0001216_abnormal_epidermal_layer0.71137476
83MP0003868_abnormal_feces_composition0.70535851
84MP0005166_decreased_susceptibility_to0.68966569
85MP0005448_abnormal_energy_balance0.67600415
86MP0009642_abnormal_blood_homeostasis0.66432849
87MP0003453_abnormal_keratinocyte_physiol0.65544925
88MP0001485_abnormal_pinna_reflex0.64651933
89MP0008872_abnormal_physiological_respon0.62074523
90MP0000249_abnormal_blood_vessel0.60180057
91MP0000230_abnormal_systemic_arterial0.59453868
92MP0000516_abnormal_urinary_system0.58691893
93MP0005367_renal/urinary_system_phenotyp0.58691893
94MP0005395_other_phenotype0.58068063
95MP0009785_altered_susceptibility_to0.56825358
96MP0002396_abnormal_hematopoietic_system0.56218526
97MP0002896_abnormal_bone_mineralization0.55752824
98MP0000377_abnormal_hair_follicle0.54934922
99MP0005334_abnormal_fat_pad0.54825554
100MP0003638_abnormal_response/metabolism_0.54494229
101MP0008004_abnormal_stomach_pH0.53711419
102MP0005266_abnormal_metabolism0.53582348
103MP0000598_abnormal_liver_morphology0.53382503
104MP0008469_abnormal_protein_level0.53361540
105MP0000467_abnormal_esophagus_morphology0.52838244
106MP0002078_abnormal_glucose_homeostasis0.52628596
107MP0002166_altered_tumor_susceptibility0.52505772
108MP0000604_amyloidosis0.52335991
109MP0003953_abnormal_hormone_level0.51744766
110MP0006138_congestive_heart_failure0.50304803
111MP0000013_abnormal_adipose_tissue0.47002997
112MP0008260_abnormal_autophagy0.46706248
113MP0000465_gastrointestinal_hemorrhage0.46391402
114MP0004782_abnormal_surfactant_physiolog0.46015438
115MP0006054_spinal_hemorrhage0.46011200
116MP0005376_homeostasis/metabolism_phenot0.45406568
117MP0001845_abnormal_inflammatory_respons0.45326936
118MP0003724_increased_susceptibility_to0.45311711
119MP0005257_abnormal_intraocular_pressure0.44133623
120MP0009384_cardiac_valve_regurgitation0.43456529
121MP0005025_abnormal_response_to0.43120641
122MP0008873_increased_physiological_sensi0.41583238
123MP0009764_decreased_sensitivity_to0.41383127
124MP0006036_abnormal_mitochondrial_physio0.41367913
125MP0005174_abnormal_tail_pigmentation0.40842169
126MP0002135_abnormal_kidney_morphology0.40537326
127MP0004957_abnormal_blastocyst_morpholog0.39845482
128MP0009333_abnormal_splenocyte_physiolog0.39042787
129MP0000383_abnormal_hair_follicle0.38963756
130MP0009053_abnormal_anal_canal0.38396466
131MP0003303_peritoneal_inflammation0.38001462

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of glutamine family amino acid metabolism (HP:0010902)6.11390851
2Ileus (HP:0002595)6.09329640
3Hyperglycinuria (HP:0003108)5.78350334
4Hyperactive renin-angiotensin system (HP:0000841)5.24690880
5Metabolic alkalosis (HP:0200114)5.22746006
6Malnutrition (HP:0004395)5.09931424
7Gout (HP:0001997)4.72257400
8Abnormality of glycine metabolism (HP:0010895)4.49147969
9Abnormality of serine family amino acid metabolism (HP:0010894)4.49147969
10Hydroxyprolinuria (HP:0003080)4.29102047
11Abnormality of proline metabolism (HP:0010907)4.29102047
12Abnormality of chloride homeostasis (HP:0011422)4.23458560
13Pustule (HP:0200039)3.80220817
14Abnormality of purine metabolism (HP:0004352)3.77095284
15Hypobetalipoproteinemia (HP:0003563)3.65652228
16Increased purine levels (HP:0004368)3.63260462
17Hyperuricemia (HP:0002149)3.63260462
18Systemic lupus erythematosus (HP:0002725)3.58994663
19Pigmentary retinal degeneration (HP:0001146)3.54357248
20Proximal tubulopathy (HP:0000114)3.50811896
21Hyperglycinemia (HP:0002154)3.39211190
22Right ventricular cardiomyopathy (HP:0011663)3.39108471
23Abnormality of renin-angiotensin system (HP:0000847)3.31098932
24Widely patent fontanelles and sutures (HP:0004492)3.25045273
25Alkalosis (HP:0001948)3.21966133
26Abnormality of urine glucose concentration (HP:0011016)3.15512291
27Glycosuria (HP:0003076)3.15512291
28Acanthocytosis (HP:0001927)3.09894346
29Increased circulating renin level (HP:0000848)3.06208544
30Abnormal tarsal ossification (HP:0008369)3.05418320
31Conjugated hyperbilirubinemia (HP:0002908)3.04463414
32Abnormality of nucleobase metabolism (HP:0010932)2.97804683
33Abdominal distention (HP:0003270)2.97770154
34Steatorrhea (HP:0002570)2.97460357
35Xanthomatosis (HP:0000991)2.96459289
36Hyperaldosteronism (HP:0000859)2.95414943
37Fat malabsorption (HP:0002630)2.94156431
38Abnormality of aspartate family amino acid metabolism (HP:0010899)2.88769705
39Flat acetabular roof (HP:0003180)2.86653031
40Dehydration (HP:0001944)2.85489205
41Autoimmune thrombocytopenia (HP:0001973)2.85222305
42Congenital sensorineural hearing impairment (HP:0008527)2.83970117
43Abnormality of magnesium homeostasis (HP:0004921)2.83546156
44Abnormality of monocarboxylic acid metabolism (HP:0010996)2.82472255
45Nephrolithiasis (HP:0000787)2.81870251
46Abnormal urine output (HP:0012590)2.81535337
47Abnormality of sulfur amino acid metabolism (HP:0004339)2.77268509
48Posterior subcapsular cataract (HP:0007787)2.76025147
49Hyperparathyroidism (HP:0000843)2.74822905
50Abnormality of renal excretion (HP:0011036)2.73135720
51Enlarged epiphyses (HP:0010580)2.69228138
52Hypokalemic alkalosis (HP:0001949)2.69147726
53Chronic diarrhea (HP:0002028)2.67815015
54Hyperammonemia (HP:0001987)2.67489796
55Abnormality of fatty-acid metabolism (HP:0004359)2.66858023
56Hypomagnesemia (HP:0002917)2.65288443
57Hypotension (HP:0002615)2.62600413
58Intrahepatic cholestasis (HP:0001406)2.61498823
59Abnormality of dicarboxylic acid metabolism (HP:0010995)2.58071903
60Dicarboxylic aciduria (HP:0003215)2.58071903
61Hemorrhage of the eye (HP:0011885)2.55864770
62Abnormality of the 1st metacarpal (HP:0010009)2.53080725
63Cupped ribs (HP:0000887)2.51723806
64Hypolipoproteinemia (HP:0010981)2.51375451
65Delayed epiphyseal ossification (HP:0002663)2.50520088
66Focal segmental glomerulosclerosis (HP:0000097)2.50384403
67Confusion (HP:0001289)2.46674130
68Villous atrophy (HP:0011473)2.45655084
69Abnormality of small intestinal villus morphology (HP:0011472)2.45655084
70Abnormality of the vitamin B12 metabolism (HP:0004341)2.44720653
71Abnormality of the costochondral junction (HP:0000919)2.42349025
72Generalized aminoaciduria (HP:0002909)2.41574753
73Vacuolated lymphocytes (HP:0001922)2.36925580
74Alopecia of scalp (HP:0002293)2.36403956
75Facial shape deformation (HP:0011334)2.35472936
76Potter facies (HP:0002009)2.35472936
77Metabolic acidosis (HP:0001942)2.33959221
78Hypokalemia (HP:0002900)2.33749258
79Nausea (HP:0002018)2.32776399
80Megaloblastic anemia (HP:0001889)2.28979955
81Abnormality of vitamin B metabolism (HP:0004340)2.27130500
82Hyperphosphaturia (HP:0003109)2.24375445
83Bundle branch block (HP:0011710)2.23334448
84Polyuria (HP:0000103)2.23306655
85Renal tubular acidosis (HP:0001947)2.22450239
86Abnormality of carpal bone ossification (HP:0006257)2.20386654
87Subcapsular cataract (HP:0000523)2.19919148
88Protuberant abdomen (HP:0001538)2.17708304
89Lethargy (HP:0001254)2.15500049
90Epidermoid cyst (HP:0200040)2.15332300
91Eczematoid dermatitis (HP:0000976)2.12112995
92Abnormal cartilage morphology (HP:0002763)2.11646838
93Gastrointestinal dysmotility (HP:0002579)2.09970443
94Tetany (HP:0001281)2.07536114
95Abnormality of the level of lipoprotein cholesterol (HP:0010979)2.06360650
96Pili torti (HP:0003777)2.03445219
97Irritability (HP:0000737)1.96960025
98Hyperphosphatemia (HP:0002905)1.96631636
99Renal salt wasting (HP:0000127)1.96441935
100Cheilitis (HP:0100825)1.96122554
101Abnormality of vitamin metabolism (HP:0100508)1.95728870
102Cerebral palsy (HP:0100021)1.95632152
103Petechiae (HP:0000967)1.95445771
104Abnormal foot bone ossification (HP:0010675)1.94923189
105Abnormal glucose tolerance (HP:0001952)1.92925066
106Abnormal urine phosphate concentration (HP:0012599)1.92749295
107Abnormal enzyme/coenzyme activity (HP:0012379)1.92375239
108Abnormality of alkaline phosphatase activity (HP:0004379)1.92195967
109Gingivitis (HP:0000230)1.92080805
110Pancreatitis (HP:0001733)1.91749096
111Glomerulosclerosis (HP:0000096)1.90617228
112Myopathic facies (HP:0002058)1.88842921
113Wide cranial sutures (HP:0010537)1.88381000
114Hypophosphatemia (HP:0002148)1.87846066
115Growth hormone excess (HP:0000845)1.87836530
116Renal tubular dysfunction (HP:0000124)1.84835814
117Abnormality of aromatic amino acid family metabolism (HP:0004338)1.84209695
118Decreased circulating renin level (HP:0003351)1.83448353
119White forelock (HP:0002211)1.82998554
120Thin bony cortex (HP:0002753)1.81580355
121Abnormality of pyrimidine metabolism (HP:0004353)1.79854176
122Vascular calcification (HP:0004934)1.79725840
123Poikilocytosis (HP:0004447)1.79316439
124Patchy hypopigmentation of hair (HP:0011365)1.78128238
125Abnormality of the distal phalanges of the toes (HP:0010182)1.77779505
126Abnormality of potassium homeostasis (HP:0011042)1.76502814
127Vomiting (HP:0002013)1.76438109
128Glomerulonephritis (HP:0000099)1.76116405
129Hypercalciuria (HP:0002150)1.75908138
130Multiple lipomas (HP:0001012)1.75444089
131Nephritis (HP:0000123)1.71222573
132Rickets (HP:0002748)1.66597214
133Metaphyseal irregularity (HP:0003025)1.66492524

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MST1R6.07850640
2FRK4.38075473
3MST43.75867301
4AKT33.74437954
5PIK3CA3.60094723
6NME13.19236445
7MAP2K23.18367551
8EPHA22.86598817
9WNK42.65197584
10WNK32.49150767
11GRK62.47569984
12RIPK12.37370004
13LMTK22.36431792
14MAP3K22.17776291
15PRKG22.07894118
16OXSR12.06985672
17MET1.88737368
18BUB11.84638002
19KSR21.58833854
20PRKCI1.51924159
21TTK1.42224696
22MYLK1.41210094
23PDK21.38787345
24NEK11.31400336
25EPHA31.30859898
26ERN11.28162171
27PTK61.27012424
28STK101.24829992
29TESK21.20596288
30TAOK11.19639717
31MAP3K81.17710796
32EPHA41.16203873
33MAP4K11.15394144
34PDK31.14563239
35PDK41.14563239
36MAP3K121.14292335
37BCKDK1.13922066
38TNIK1.10856844
39STK241.10566809
40PRPF4B1.08261059
41RIPK41.02398109
42MAP2K10.98882956
43EPHB20.97062237
44WEE10.94611492
45PIM20.92970712
46IRAK30.89915298
47NUAK10.89762831
48TESK10.86597181
49STK38L0.86316707
50STK390.86266479
51CDC42BPA0.84580587
52TRIB30.84086882
53FGFR30.83766511
54PTK20.82845284
55TAOK30.82657589
56MAP3K100.82592712
57PAK40.81053990
58DDR20.76615463
59ARAF0.75026130
60FGFR40.75012245
61PRKAA20.73910158
62MATK0.72489052
63EPHB10.68971423
64EEF2K0.68873230
65PRKAA10.66040669
66MAP3K30.65970823
67SIK10.63781685
68NEK20.61006265
69AURKB0.60741397
70ACVR1B0.60450329
71MAPK110.60128794
72MAP3K110.59054425
73PDPK10.59039051
74PRKCZ0.55563957
75ERBB20.55421609
76TYK20.51250735
77SMG10.49679125
78LRRK20.49518801
79RET0.48867559
80BRSK20.48751775
81EIF2AK10.48610951
82FER0.48450585
83BRAF0.48360415
84STK30.47521343
85PDGFRA0.47319052
86MAP3K10.46261950
87MAP3K70.46241218
88NME20.46104293
89SRC0.46049606
90MELK0.46046947
91CDK60.43319387
92PAK10.43015717
93PIM10.40653288
94FYN0.40296339
95ABL20.39511335
96CAMK2D0.39253233
97IRAK10.39212406
98CSF1R0.37848847
99ICK0.37346830
100LATS10.36377915
101RPS6KA20.36235365
102CDK190.35796623
103CSNK1A10.34887655
104NEK60.34613667
105MAPKAPK30.34545825
106GSK3A0.34192115
107PLK40.33573307
108STK110.33473968
109DYRK1B0.33211841
110CSK0.31944462
111TSSK60.31938358
112ZAP700.31112266
113BTK0.30929795
114PDK10.30646562
115ITK0.28986945
116JAK10.28936656
117YES10.28033875
118PRKCA0.27381361
119MAP2K60.27078618
120AKT20.26537254
121CHEK20.26291470
122CAMK2G0.25044373
123MAPK70.24371864
124DMPK0.24216210
125PAK20.24091688
126CAMK2B0.22619852
127IKBKE0.21713299
128JAK20.21672259
129IGF1R0.21628984
130CASK0.21402125
131PRKACG0.21329527
132PLK10.20095394
133BMPR20.19866675
134PRKACA0.19023630
135NLK0.18310041
136DYRK30.18246711
137KDR0.17479969
138TBK10.16964246
139GRK10.16942341
140BMX0.16933643
141PRKCD0.16709508

Predicted pathways (KEGG)

RankGene SetZ-score
1Vitamin digestion and absorption_Homo sapiens_hsa049773.79815602
2Fat digestion and absorption_Homo sapiens_hsa049753.66111183
3Mineral absorption_Homo sapiens_hsa049783.58049498
4Renin-angiotensin system_Homo sapiens_hsa046143.38357750
5Sulfur metabolism_Homo sapiens_hsa009203.37954446
6Butirosin and neomycin biosynthesis_Homo sapiens_hsa005243.17528577
7Folate biosynthesis_Homo sapiens_hsa007902.66078119
8Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.58882763
9Bile secretion_Homo sapiens_hsa049762.40382715
10Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.26124736
11Pantothenate and CoA biosynthesis_Homo sapiens_hsa007702.21435647
12Cyanoamino acid metabolism_Homo sapiens_hsa004602.17328764
13Pentose and glucuronate interconversions_Homo sapiens_hsa000402.17276225
14Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.12878858
15Galactose metabolism_Homo sapiens_hsa000522.11367797
16Starch and sucrose metabolism_Homo sapiens_hsa005002.05183649
17Fructose and mannose metabolism_Homo sapiens_hsa000511.89011591
18Caffeine metabolism_Homo sapiens_hsa002321.88278463
19Tryptophan metabolism_Homo sapiens_hsa003801.88011492
20Histidine metabolism_Homo sapiens_hsa003401.83523794
21Butanoate metabolism_Homo sapiens_hsa006501.80911307
222-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.80372661
23Protein digestion and absorption_Homo sapiens_hsa049741.77046306
24Vitamin B6 metabolism_Homo sapiens_hsa007501.68006851
25Glutathione metabolism_Homo sapiens_hsa004801.65361825
26Carbohydrate digestion and absorption_Homo sapiens_hsa049731.59095773
27Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.58550710
28PPAR signaling pathway_Homo sapiens_hsa033201.55377137
29Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.53504762
30Fatty acid degradation_Homo sapiens_hsa000711.53259093
31Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.51587779
32Maturity onset diabetes of the young_Homo sapiens_hsa049501.49846723
33Drug metabolism - other enzymes_Homo sapiens_hsa009831.45654070
34Glycerolipid metabolism_Homo sapiens_hsa005611.43996017
35Arginine biosynthesis_Homo sapiens_hsa002201.39159958
36Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.33200358
37Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.27540575
38Carbon metabolism_Homo sapiens_hsa012001.17798422
39Arginine and proline metabolism_Homo sapiens_hsa003301.17286057
40Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.16414758
41beta-Alanine metabolism_Homo sapiens_hsa004101.15174104
42Peroxisome_Homo sapiens_hsa041461.13472133
43Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.07790628
44Pentose phosphate pathway_Homo sapiens_hsa000301.07258610
45Sphingolipid metabolism_Homo sapiens_hsa006001.06345651
46Glycerophospholipid metabolism_Homo sapiens_hsa005641.03655221
47Propanoate metabolism_Homo sapiens_hsa006401.01416000
48Pyruvate metabolism_Homo sapiens_hsa006200.99772135
49Steroid hormone biosynthesis_Homo sapiens_hsa001400.99558352
50Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.97721512
51Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.97415941
52Ether lipid metabolism_Homo sapiens_hsa005650.91788484
53Fatty acid metabolism_Homo sapiens_hsa012120.87980226
54Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.86180559
55Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.82912846
56Biosynthesis of amino acids_Homo sapiens_hsa012300.82772660
57Primary bile acid biosynthesis_Homo sapiens_hsa001200.82299626
58Nitrogen metabolism_Homo sapiens_hsa009100.81920622
59Chemical carcinogenesis_Homo sapiens_hsa052040.80552710
60Selenocompound metabolism_Homo sapiens_hsa004500.80326272
61Asthma_Homo sapiens_hsa053100.77252121
62Retinol metabolism_Homo sapiens_hsa008300.77073255
63Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.74662252
64ABC transporters_Homo sapiens_hsa020100.72361654
65Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.70555307
66Cysteine and methionine metabolism_Homo sapiens_hsa002700.69383050
67alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.64400277
68Metabolic pathways_Homo sapiens_hsa011000.62293478
69Sulfur relay system_Homo sapiens_hsa041220.61137155
70Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.53761177
71Arachidonic acid metabolism_Homo sapiens_hsa005900.50772969
72Allograft rejection_Homo sapiens_hsa053300.50464069
73Fatty acid biosynthesis_Homo sapiens_hsa000610.49042503
74Phenylalanine metabolism_Homo sapiens_hsa003600.46658052
75Tight junction_Homo sapiens_hsa045300.46407703
76Autoimmune thyroid disease_Homo sapiens_hsa053200.45962670
77Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.44775908
78Graft-versus-host disease_Homo sapiens_hsa053320.43255336
79Staphylococcus aureus infection_Homo sapiens_hsa051500.42874709
80Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.42401016
81Linoleic acid metabolism_Homo sapiens_hsa005910.39635894
82Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.38349099
83Regulation of autophagy_Homo sapiens_hsa041400.37980759
84Renin secretion_Homo sapiens_hsa049240.37832681
85Thyroid hormone synthesis_Homo sapiens_hsa049180.35914873
86Adipocytokine signaling pathway_Homo sapiens_hsa049200.34960006
87Other glycan degradation_Homo sapiens_hsa005110.31958950
88Type I diabetes mellitus_Homo sapiens_hsa049400.26867246
89Cocaine addiction_Homo sapiens_hsa050300.25439579
90Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.23438394
91Glucagon signaling pathway_Homo sapiens_hsa049220.23422890
92Pancreatic secretion_Homo sapiens_hsa049720.22959204
93Intestinal immune network for IgA production_Homo sapiens_hsa046720.21660388
94Hepatitis C_Homo sapiens_hsa051600.21567510
95Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.21161275
96Fatty acid elongation_Homo sapiens_hsa000620.20641890
97Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.19843529
98Bladder cancer_Homo sapiens_hsa052190.17011273
99Lysine degradation_Homo sapiens_hsa003100.14394349
100Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.14339982
101Steroid biosynthesis_Homo sapiens_hsa001000.12846018
102Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.11631567
103Thyroid cancer_Homo sapiens_hsa052160.11032836
104Antigen processing and presentation_Homo sapiens_hsa046120.10204141
105Purine metabolism_Homo sapiens_hsa002300.09769894
106AMPK signaling pathway_Homo sapiens_hsa041520.08630308
107Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.08379051
108Insulin secretion_Homo sapiens_hsa049110.08152743
109Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.07725825
110Leukocyte transendothelial migration_Homo sapiens_hsa046700.07723376
111Leishmaniasis_Homo sapiens_hsa051400.07272986
112Amphetamine addiction_Homo sapiens_hsa050310.06504071
113Tyrosine metabolism_Homo sapiens_hsa003500.05892795
114Lysosome_Homo sapiens_hsa041420.05631738
115Oxidative phosphorylation_Homo sapiens_hsa001900.03755544
116Serotonergic synapse_Homo sapiens_hsa047260.03723234
117Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.03586402
118Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.03469478
119Pyrimidine metabolism_Homo sapiens_hsa002400.02621581
120Insulin resistance_Homo sapiens_hsa049310.01603627
121Complement and coagulation cascades_Homo sapiens_hsa046100.00948423
122GnRH signaling pathway_Homo sapiens_hsa049120.00801346
123Collecting duct acid secretion_Homo sapiens_hsa04966-0.0112570
124Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533-0.0086032

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »