SLC15A4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative regulation of leukocyte mediated cytotoxicity (GO:0001911)5.74129043
2negative regulation of cell killing (GO:0031342)5.74129043
3detection of molecule of bacterial origin (GO:0032490)4.98873105
4modulation by symbiont of host defense response (GO:0052031)4.84726084
5modulation by organism of immune response of other organism involved in symbiotic interaction (GO:004.84726084
6modulation by organism of defense response of other organism involved in symbiotic interaction (GO:04.84726084
7positive regulation by organism of defense response of other organism involved in symbiotic interact4.84726084
8modulation by symbiont of host immune response (GO:0052553)4.84726084
9positive regulation by symbiont of host defense response (GO:0052509)4.84726084
10detection of other organism (GO:0098543)4.66733959
11positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)4.65009429
12regulation of B cell receptor signaling pathway (GO:0050855)4.51573168
13regulation of interferon-beta biosynthetic process (GO:0045357)4.45110146
14detection of external biotic stimulus (GO:0098581)4.42818223
15detection of bacterium (GO:0016045)4.36253676
16cellular extravasation (GO:0045123)4.23843863
17cellular response to type I interferon (GO:0071357)4.14893162
18type I interferon signaling pathway (GO:0060337)4.14893162
19antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G4.12638984
20response to type I interferon (GO:0034340)4.11607843
21neutrophil activation involved in immune response (GO:0002283)4.08990245
22B cell receptor signaling pathway (GO:0050853)4.02766520
23positive regulation of gamma-delta T cell activation (GO:0046645)3.99356375
24macrophage activation involved in immune response (GO:0002281)3.98720311
25response to interleukin-15 (GO:0070672)3.96549241
26negative regulation of lymphocyte mediated immunity (GO:0002707)3.85198509
27positive regulation of B cell differentiation (GO:0045579)3.84749147
28detection of biotic stimulus (GO:0009595)3.83479413
29antigen processing and presentation of endogenous antigen (GO:0019883)3.79679095
30positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)3.78302389
31cellular response to interleukin-15 (GO:0071350)3.76788227
32negative regulation of T cell mediated immunity (GO:0002710)3.70499650
33T-helper 1 type immune response (GO:0042088)3.68509002
34positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.66086001
35interferon-gamma-mediated signaling pathway (GO:0060333)3.61528919
36erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)3.58770979
37L-phenylalanine catabolic process (GO:0006559)3.58770979
38regulation of nitric-oxide synthase biosynthetic process (GO:0051769)3.56632216
39respiratory burst (GO:0045730)3.56284832
40positive regulation of interferon-alpha production (GO:0032727)3.54463308
41positive regulation of antigen processing and presentation (GO:0002579)3.51388414
42immunoglobulin mediated immune response (GO:0016064)3.45918786
43response to muramyl dipeptide (GO:0032495)3.45495108
44positive regulation of interleukin-8 biosynthetic process (GO:0045416)3.44691827
45regulation of B cell differentiation (GO:0045577)3.38618625
46aromatic amino acid family catabolic process (GO:0009074)3.38147804
47regulation of interferon-alpha production (GO:0032647)3.35691109
48response to peptidoglycan (GO:0032494)3.35018992
49B cell mediated immunity (GO:0019724)3.29672340
50negative regulation of leukocyte mediated immunity (GO:0002704)3.28723736
51microglial cell activation (GO:0001774)3.27484328
52positive regulation of toll-like receptor signaling pathway (GO:0034123)3.24727436
53production of molecular mediator involved in inflammatory response (GO:0002532)3.23247361
54regulation of gamma-delta T cell differentiation (GO:0045586)3.21504916
55neutrophil activation (GO:0042119)3.20156165
56erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)3.18778643
57L-phenylalanine metabolic process (GO:0006558)3.18778643
58regulation of tumor necrosis factor biosynthetic process (GO:0042534)3.17465899
59antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.17002293
60antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.17002293
61response to protozoan (GO:0001562)3.16555222
62regulation of T cell mediated cytotoxicity (GO:0001914)3.16447850
63negative thymic T cell selection (GO:0045060)3.16168029
64mature B cell differentiation (GO:0002335)3.13360809
65negative regulation of interleukin-1 beta production (GO:0032691)3.13243387
66positive regulation of cellular amide metabolic process (GO:0034250)3.10087681
67regulation of MHC class I biosynthetic process (GO:0045343)3.08986383
68urea cycle (GO:0000050)3.08652379
69urea metabolic process (GO:0019627)3.08652379
70regulation of dendritic cell antigen processing and presentation (GO:0002604)3.07706366
71tryptophan catabolic process (GO:0006569)3.06204060
72indole-containing compound catabolic process (GO:0042436)3.06204060
73indolalkylamine catabolic process (GO:0046218)3.06204060
74I-kappaB phosphorylation (GO:0007252)3.05501838
75T cell migration (GO:0072678)3.05276369
76nitrogen cycle metabolic process (GO:0071941)3.04141999
77regulation of alpha-beta T cell proliferation (GO:0046640)3.03771609
78NIK/NF-kappaB signaling (GO:0038061)3.02968564
79response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.02513965
80response to host immune response (GO:0052572)3.02513965
81regulation of T cell tolerance induction (GO:0002664)3.02345945
82positive regulation of T cell mediated cytotoxicity (GO:0001916)3.02230545
83antigen processing and presentation via MHC class Ib (GO:0002475)3.00084009
84negative T cell selection (GO:0043383)2.98534713
85regulation of antigen processing and presentation (GO:0002577)2.94283724
86granulocyte activation (GO:0036230)2.93699295
87regulation of superoxide anion generation (GO:0032928)2.93000797
88neutrophil mediated immunity (GO:0002446)2.92548798
89negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.92377815
90germinal center formation (GO:0002467)2.90692401
91positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.89651109
92myeloid leukocyte mediated immunity (GO:0002444)2.89241626
93natural killer cell mediated immunity (GO:0002228)2.89032447
94natural killer cell mediated cytotoxicity (GO:0042267)2.89032447
95regulation of tolerance induction (GO:0002643)2.87917534
96macrophage activation (GO:0042116)2.87521316
97regulation of interferon-beta production (GO:0032648)2.87160591
98regulation of interleukin-12 production (GO:0032655)2.86949638
99leukocyte migration involved in inflammatory response (GO:0002523)2.86656844
100tryptophan metabolic process (GO:0006568)2.85839424
101B cell homeostasis (GO:0001782)2.85121285
102complement activation, classical pathway (GO:0006958)2.84428134
103myeloid leukocyte activation (GO:0002274)2.81733847
104response to lipoprotein particle (GO:0055094)2.81710583
105fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)2.81455227
106myeloid cell activation involved in immune response (GO:0002275)2.81415690
107negative regulation of interleukin-12 production (GO:0032695)2.79316360
108plasma lipoprotein particle clearance (GO:0034381)2.79283790
109protein carboxylation (GO:0018214)2.79048000
110peptidyl-glutamic acid carboxylation (GO:0017187)2.79048000
111leukocyte degranulation (GO:0043299)2.78255337
112dendritic cell migration (GO:0036336)2.77709267
113natural killer cell activation involved in immune response (GO:0002323)2.77131455
114negative regulation of phagocytosis (GO:0050765)2.76166608
115phospholipid efflux (GO:0033700)2.75990172
116pinocytosis (GO:0006907)2.75700055
117regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.75492026
118negative regulation of alpha-beta T cell activation (GO:0046636)2.75249167
119negative regulation of innate immune response (GO:0045824)2.75206681
120regulation of mast cell degranulation (GO:0043304)2.75050879
121negative regulation of B cell proliferation (GO:0030889)2.71689727
122triglyceride-rich lipoprotein particle remodeling (GO:0034370)2.71396638
123amyloid precursor protein catabolic process (GO:0042987)2.70307764
124response to host (GO:0075136)2.70306852
125response to host defenses (GO:0052200)2.70306852
126response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.70306852
127positive regulation of interferon-beta production (GO:0032728)2.68778611
128phospholipid homeostasis (GO:0055091)2.68741610
129defense response to protozoan (GO:0042832)2.66532252
130complement activation, alternative pathway (GO:0006957)2.65440568
131cholesterol efflux (GO:0033344)2.64719483
132negative regulation of interleukin-1 production (GO:0032692)2.63555380
133complement activation (GO:0006956)2.63547294
134kynurenine metabolic process (GO:0070189)2.61537555
135protein-lipid complex assembly (GO:0065005)2.61457440
136negative regulation of granulocyte differentiation (GO:0030853)2.61221813
137tolerance induction (GO:0002507)2.61204413
138bile acid biosynthetic process (GO:0006699)2.59969974
139regulation of gamma-delta T cell activation (GO:0046643)2.59935190
140regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.58970572
141negative regulation of interleukin-6 production (GO:0032715)2.58151107
142tyrosine metabolic process (GO:0006570)2.55863322
143regulation of interleukin-12 biosynthetic process (GO:0045075)2.53822644
144positive thymic T cell selection (GO:0045059)2.52712070
145regulation of mast cell activation involved in immune response (GO:0033006)2.52614700
146regulation of mast cell activation (GO:0033003)2.50843880
147regulation of interleukin-8 biosynthetic process (GO:0045414)2.48887098
148cytokine secretion (GO:0050663)2.47918170
149lipopolysaccharide-mediated signaling pathway (GO:0031663)2.47280773
150leukocyte aggregation (GO:0070486)2.46666062

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human5.77248196
2IRF8_21731497_ChIP-ChIP_J774_Mouse5.46487351
3ESR1_17901129_ChIP-ChIP_LIVER_Mouse4.22484694
4IRF8_27001747_Chip-Seq_BMDM_Mouse3.99855514
5* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse3.71272000
6IRF8_22096565_ChIP-ChIP_GC-B_Mouse3.56270042
7EGR1_23403033_ChIP-Seq_LIVER_Mouse3.48255293
8FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.40676392
9* RXR_22158963_ChIP-Seq_LIVER_Mouse3.23227511
10MECOM_23826213_ChIP-Seq_KASUMI_Mouse3.09282882
11* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse3.07863711
12Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse3.06648721
13BP1_19119308_ChIP-ChIP_Hs578T_Human3.05935929
14PPARA_22158963_ChIP-Seq_LIVER_Mouse2.91157770
15SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.76552914
16SMAD_19615063_ChIP-ChIP_OVARY_Human2.75447001
17* LXR_22158963_ChIP-Seq_LIVER_Mouse2.66135151
18MYB_21317192_ChIP-Seq_ERMYB_Mouse2.64170558
19IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.63315942
20SCL_19346495_ChIP-Seq_HPC-7_Human2.46330045
21VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.38292617
22CEBPA_23403033_ChIP-Seq_LIVER_Mouse2.21050163
23NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.15194349
24VDR_21846776_ChIP-Seq_THP-1_Human2.11313611
25CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.09897250
26BRD4_27068464_Chip-Seq_AML-cells_Mouse2.08857606
27STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.07351404
28RUNX_20019798_ChIP-Seq_JUKART_Human2.03118342
29STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.99444658
30SPI1_23547873_ChIP-Seq_NB4_Human1.98371495
31RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.94336357
32VDR_24763502_ChIP-Seq_THP-1_Human1.93517294
33RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.85039198
34FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.82648912
35* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.81369393
36FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.80686373
37SPI1_23127762_ChIP-Seq_K562_Human1.79059067
38STAT4_19710469_ChIP-ChIP_TH1__Mouse1.77042408
39RUNX1_22412390_ChIP-Seq_EML_Mouse1.69896595
40MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.68539644
41MYB_26560356_Chip-Seq_TH2_Human1.68288590
42EGR1_19374776_ChIP-ChIP_THP-1_Human1.67055978
43* MYB_26560356_Chip-Seq_TH1_Human1.65398132
44PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.64737649
45GATA1_22025678_ChIP-Seq_K562_Human1.61012791
46* MAF_26560356_Chip-Seq_TH1_Human1.56705549
47PU_27001747_Chip-Seq_BMDM_Mouse1.54816350
48CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.54002905
49NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.51219530
50STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.50520740
51SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.49059175
52PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.42403648
53VDR_24787735_ChIP-Seq_THP-1_Human1.39737914
54LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.36942773
55NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.35991778
56NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.32184575
57CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.27943294
58CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.27419679
59FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.25384444
60LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.25133042
61SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.22897688
62ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.21484833
63GATA2_22383799_ChIP-Seq_G1ME_Mouse1.21428582
64UTX_26944678_Chip-Seq_JUKART_Human1.18401575
65CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.18268049
66GATA3_27048872_Chip-Seq_THYMUS_Human1.15462260
67GATA2_21666600_ChIP-Seq_HMVEC_Human1.14415675
68MYC_22102868_ChIP-Seq_BL_Human1.14097720
69PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.12792735
70THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.12262341
71GATA3_26560356_Chip-Seq_TH2_Human1.11854302
72FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.10734931
73TCF7_22412390_ChIP-Seq_EML_Mouse1.10604831
74SMRT_27268052_Chip-Seq_Bcells_Human1.09787259
75GATA1_22383799_ChIP-Seq_G1ME_Mouse1.09240025
76PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.08298020
77GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.08296567
78GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.07559833
79BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.06685945
80GATA1_19941827_ChIP-Seq_MEL_Mouse1.05808839
81KDM2B_26808549_Chip-Seq_DND41_Human1.02273258
82CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.00392617
83NOTCH1_21737748_ChIP-Seq_TLL_Human0.99490468
84SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.98677785
85PU.1_20513432_ChIP-Seq_Bcells_Mouse0.98670907
86RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.98033887
87TFEB_21752829_ChIP-Seq_HELA_Human0.95937245
88CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.94180532
89SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.90970852
90STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.89507025
91MAF_26560356_Chip-Seq_TH2_Human0.89087770
92TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.88815440
93KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.86785045
94FOXA2_19822575_ChIP-Seq_HepG2_Human0.84698200
95GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.83501361
96TCF7L2_21901280_ChIP-Seq_H4IIE_Rat0.83130726
97SPI1_20517297_ChIP-Seq_HL60_Human0.82832849
98GATA2_19941826_ChIP-Seq_K562_Human0.82780838
99KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.82471957
100GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.81924063
101GATA1_19941826_ChIP-Seq_K562_Human0.78632469
102RXRA_24833708_ChIP-Seq_LIVER_Mouse0.78620684
103KDM2B_26808549_Chip-Seq_SUP-B15_Human0.77588350
104GATA1_19941827_ChIP-Seq_MEL86_Mouse0.77448901
105SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.75458590
106E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.75100663
107ELK3_25401928_ChIP-Seq_HUVEC_Human0.74209529
108FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.74170389
109VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.73243214
110TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.70519936
111FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.68766409
112* RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.65520115
113GATA3_26560356_Chip-Seq_TH1_Human0.63411919
114TP53_16413492_ChIP-PET_HCT116_Human0.63124445
115FOXO3_23340844_ChIP-Seq_DLD1_Human0.62678329
116KDM2B_26808549_Chip-Seq_JURKAT_Human0.62401501
117TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.61220096
118BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.58262213
119TP63_23658742_ChIP-Seq_EP156T_Human0.57360276

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation4.04433906
2MP0009840_abnormal_foam_cell3.41314936
3MP0002139_abnormal_hepatobiliary_system3.07838119
4MP0005387_immune_system_phenotype2.90542326
5MP0001790_abnormal_immune_system2.90542326
6MP0005058_abnormal_lysosome_morphology2.83686307
7MP0005360_urolithiasis2.82674433
8MP0001800_abnormal_humoral_immune2.81710202
9MP0003191_abnormal_cellular_cholesterol2.78909408
10MP0002419_abnormal_innate_immunity2.64775055
11MP0003303_peritoneal_inflammation2.61026210
12MP0003436_decreased_susceptibility_to2.53493202
13MP0002452_abnormal_antigen_presenting2.49630068
14MP0005000_abnormal_immune_tolerance2.49034669
15MP0000685_abnormal_immune_system2.46270564
16* MP0002723_abnormal_immune_serum2.33386686
17MP0004510_myositis2.26265418
18MP0005365_abnormal_bile_salt2.25193556
19MP0006082_CNS_inflammation2.24892171
20MP0005025_abnormal_response_to2.21210783
21MP0005085_abnormal_gallbladder_physiolo2.16939888
22MP0005671_abnormal_response_to2.16569552
23MP0005451_abnormal_body_composition2.08632757
24MP0005464_abnormal_platelet_physiology2.07563751
25MP0003172_abnormal_lysosome_physiology2.04948621
26MP0002420_abnormal_adaptive_immunity2.02686981
27MP0009785_altered_susceptibility_to2.02222140
28MP0001819_abnormal_immune_cell2.01676282
29MP0002148_abnormal_hypersensitivity_rea1.94664766
30MP0000569_abnormal_digit_pigmentation1.94462819
31MP0008875_abnormal_xenobiotic_pharmacok1.76132499
32MP0001853_heart_inflammation1.70664452
33MP0003828_pulmonary_edema1.69779666
34MP0004947_skin_inflammation1.67745452
35MP0008260_abnormal_autophagy1.65659548
36MP0000716_abnormal_immune_system1.63560031
37MP0000689_abnormal_spleen_morphology1.57995280
38MP0004381_abnormal_hair_follicle1.57629853
39MP0008469_abnormal_protein_level1.53874546
40MP0003690_abnormal_glial_cell1.53298771
41MP0001845_abnormal_inflammatory_respons1.53085724
42MP0002398_abnormal_bone_marrow1.49659781
43MP0003806_abnormal_nucleotide_metabolis1.49580604
44MP0003252_abnormal_bile_duct1.48073048
45MP0003724_increased_susceptibility_to1.47900748
46MP0009764_decreased_sensitivity_to1.45925533
47MP0003656_abnormal_erythrocyte_physiolo1.44134552
48MP0000920_abnormal_myelination1.42725838
49MP0004883_abnormal_blood_vessel1.41990204
50MP0002166_altered_tumor_susceptibility1.41306876
51MP0002138_abnormal_hepatobiliary_system1.41123808
52MP0002405_respiratory_system_inflammati1.39132712
53MP0002277_abnormal_respiratory_mucosa1.37133296
54MP0005310_abnormal_salivary_gland1.34974272
55MP0000465_gastrointestinal_hemorrhage1.33956093
56MP0000609_abnormal_liver_physiology1.33293320
57MP0002429_abnormal_blood_cell1.30300328
58MP0000604_amyloidosis1.29540084
59MP0010329_abnormal_lipoprotein_level1.26317416
60MP0009278_abnormal_bone_marrow1.25080001
61MP0003045_fibrosis1.23612265
62MP0002722_abnormal_immune_system1.23598616
63MP0000703_abnormal_thymus_morphology1.22995343
64MP0001533_abnormal_skeleton_physiology1.20469382
65MP0002933_joint_inflammation1.20303804
66MP0000015_abnormal_ear_pigmentation1.19690193
67MP0009333_abnormal_splenocyte_physiolog1.18569561
68MP0002132_abnormal_respiratory_system1.17886542
69MP0003195_calcinosis1.17205450
70MP0005075_abnormal_melanosome_morpholog1.16196262
71MP0003183_abnormal_peptide_metabolism1.14476846
72MP0005164_abnormal_response_to1.14042374
73MP0005174_abnormal_tail_pigmentation1.13773972
74MP0010155_abnormal_intestine_physiology1.12681943
75MP0002396_abnormal_hematopoietic_system1.11705703
76MP0009763_increased_sensitivity_to1.10412380
77MP0003453_abnormal_keratinocyte_physiol1.10234127
78MP0003300_gastrointestinal_ulcer1.07537893
79MP0005083_abnormal_biliary_tract1.05677364
80MP0002254_reproductive_system_inflammat1.05617083
81MP0000858_altered_metastatic_potential1.04710177
82MP0005408_hypopigmentation1.02792331
83MP0001873_stomach_inflammation1.00788595
84MP0002006_tumorigenesis0.99447095
85MP0002118_abnormal_lipid_homeostasis0.97225534
86MP0003866_abnormal_defecation0.97046375
87MP0005397_hematopoietic_system_phenotyp0.97008429
88MP0001545_abnormal_hematopoietic_system0.97008429
89MP0005584_abnormal_enzyme/coenzyme_acti0.95739062
90MP0003091_abnormal_cell_migration0.94874216
91MP0006054_spinal_hemorrhage0.91106674
92MP0003075_altered_response_to0.88219872
93MP0001851_eye_inflammation0.86858156
94MP0003221_abnormal_cardiomyocyte_apopto0.86510087
95MP0002998_abnormal_bone_remodeling0.85676485
96MP0002332_abnormal_exercise_endurance0.85560202
97MP0002163_abnormal_gland_morphology0.85098474
98MP0008057_abnormal_DNA_replication0.84439167
99MP0000371_diluted_coat_color0.83993566
100MP0005257_abnormal_intraocular_pressure0.83916710
101MP0009765_abnormal_xenobiotic_induced0.83767290
102MP0003763_abnormal_thymus_physiology0.83763239
103MP0004808_abnormal_hematopoietic_stem0.83344750
104MP0000383_abnormal_hair_follicle0.78397439
105MP0000343_altered_response_to0.77757306
106MP0000598_abnormal_liver_morphology0.77712002
107MP0005166_decreased_susceptibility_to0.77656891
108MP0005379_endocrine/exocrine_gland_phen0.76415703
109MP0002136_abnormal_kidney_physiology0.76326437
110MP0002693_abnormal_pancreas_physiology0.74292974
111MP0002928_abnormal_bile_duct0.74285385
112MP0001666_abnormal_nutrient_absorption0.73228188
113MP0000372_irregular_coat_pigmentation0.72349758
114MP0003448_altered_tumor_morphology0.71267034
115MP0005332_abnormal_amino_acid0.71239939
116MP0004484_altered_response_of0.70250604
117MP0003868_abnormal_feces_composition0.69308204
118MP0000249_abnormal_blood_vessel0.68110356
119MP0005390_skeleton_phenotype0.66871190
120MP0008873_increased_physiological_sensi0.66724477
121MP0009697_abnormal_copulation0.66593326
122MP0003646_muscle_fatigue0.64388744
123MP0010678_abnormal_skin_adnexa0.64238398
124MP0005319_abnormal_enzyme/_coenzyme0.63473298
125MP0003186_abnormal_redox_activity0.62933363
126MP0008874_decreased_physiological_sensi0.61163274
127MP0002168_other_aberrant_phenotype0.60532369
128MP0003795_abnormal_bone_structure0.59224226
129MP0005084_abnormal_gallbladder_morpholo0.55459703

Predicted human phenotypes

RankGene SetZ-score
1Recurrent abscess formation (HP:0002722)5.24903350
2Recurrent bacterial skin infections (HP:0005406)5.17631310
3Recurrent gram-negative bacterial infections (HP:0005420)4.28243438
4Systemic lupus erythematosus (HP:0002725)4.06244504
5Recurrent skin infections (HP:0001581)4.01015361
6Gastrointestinal infarctions (HP:0005244)3.89671940
7Eczematoid dermatitis (HP:0000976)3.79856769
8Colitis (HP:0002583)3.76818400
9Keratoconjunctivitis sicca (HP:0001097)3.73766439
10Joint hemorrhage (HP:0005261)3.56238144
11Keratoconjunctivitis (HP:0001096)3.53217592
12Agammaglobulinemia (HP:0004432)3.46935761
13Complement deficiency (HP:0004431)3.42921847
14Glomerulonephritis (HP:0000099)3.42725037
15Myocardial infarction (HP:0001658)3.38990019
16Elevated erythrocyte sedimentation rate (HP:0003565)3.38066607
17Gingival bleeding (HP:0000225)3.35566331
18T lymphocytopenia (HP:0005403)3.34146548
19Abnormality of aromatic amino acid family metabolism (HP:0004338)3.32780262
20Abnormality of T cell number (HP:0011839)3.30250085
21Intrahepatic cholestasis (HP:0001406)3.29878455
22Inflammation of the large intestine (HP:0002037)3.26839973
23Abnormality of macrophages (HP:0004311)3.25908238
24Prolonged partial thromboplastin time (HP:0003645)3.15389345
25Deep venous thrombosis (HP:0002625)3.13170805
26Amyloidosis (HP:0011034)3.12120619
27Abnormality of glycolipid metabolism (HP:0010969)3.11718052
28Abnormality of liposaccharide metabolism (HP:0010968)3.11718052
29Abnormality of glycosphingolipid metabolism (HP:0004343)3.11718052
30Recurrent viral infections (HP:0004429)3.10928318
31Chronic otitis media (HP:0000389)3.06826733
32Recurrent fungal infections (HP:0002841)3.06629591
33Gastrointestinal stroma tumor (HP:0100723)3.05117036
34Loss of speech (HP:0002371)3.04868353
35Vasculitis (HP:0002633)3.03874431
36Xanthomatosis (HP:0000991)3.03152431
37Chest pain (HP:0100749)3.02887139
38Gastrointestinal inflammation (HP:0004386)3.02407729
39Hemoptysis (HP:0002105)3.01668855
40Recurrent cutaneous fungal infections (HP:0011370)3.00503486
41Chronic mucocutaneous candidiasis (HP:0002728)3.00503486
42Arterial thrombosis (HP:0004420)3.00099614
43Mediastinal lymphadenopathy (HP:0100721)2.98575005
44Axonal loss (HP:0003447)2.93128157
45Cellulitis (HP:0100658)2.91972182
46Abnormality of monocarboxylic acid metabolism (HP:0010996)2.87700846
47Increased IgE level (HP:0003212)2.87260956
48Hyperlipoproteinemia (HP:0010980)2.85570394
49Episodic fever (HP:0001954)2.83331197
50Vacuolated lymphocytes (HP:0001922)2.80759308
51Abnormality of T cells (HP:0002843)2.79276952
52Abnormality of complement system (HP:0005339)2.78109300
53Meningitis (HP:0001287)2.75996211
54Pustule (HP:0200039)2.69320818
55Increased cerebral lipofuscin (HP:0011813)2.68479411
56Myositis (HP:0100614)2.68129390
57Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.66359330
58Osteomyelitis (HP:0002754)2.65175139
59Abnormal delayed hypersensitivity skin test (HP:0002963)2.65169770
60Stomatitis (HP:0010280)2.65115076
61Increased IgM level (HP:0003496)2.64732747
62Gingivitis (HP:0000230)2.62162288
63Mitral stenosis (HP:0001718)2.58758481
64Anorexia (HP:0002039)2.55392442
65Chronic obstructive pulmonary disease (HP:0006510)2.53749095
66Obstructive lung disease (HP:0006536)2.53749095
67Abnormality of T cell physiology (HP:0011840)2.51372752
68Abnormality of the pleura (HP:0002103)2.47937849
69Viral hepatitis (HP:0006562)2.47122249
70Recurrent sinusitis (HP:0011108)2.46933592
71Gangrene (HP:0100758)2.43474425
72Increased neuronal autofluorescent lipopigment (HP:0002074)2.42069305
73Thick nail (HP:0001805)2.39967123
74Peritonitis (HP:0002586)2.39651750
75Abnormality of pyrimidine metabolism (HP:0004353)2.38000228
76Hepatosplenomegaly (HP:0001433)2.36667363
77IgM deficiency (HP:0002850)2.35188297
78Abnormality of the peritoneum (HP:0002585)2.34896955
79Epistaxis (HP:0000421)2.34151734
80Sepsis (HP:0100806)2.33225560
81Hypochromic anemia (HP:0001931)2.29457630
82Prolonged bleeding time (HP:0003010)2.29196389
83Orchitis (HP:0100796)2.28745027
84Dysostosis multiplex (HP:0000943)2.28699169
85Parakeratosis (HP:0001036)2.28260006
86Recurrent pneumonia (HP:0006532)2.27219958
87Optic neuritis (HP:0100653)2.27057414
88Retrobulbar optic neuritis (HP:0100654)2.27057414
89Periodontitis (HP:0000704)2.22298147
90Upper motor neuron abnormality (HP:0002127)2.22038582
91Granulocytopenia (HP:0001913)2.21931339
92Abnormal platelet function (HP:0011869)2.21689506
93Impaired platelet aggregation (HP:0003540)2.21689506
94Disinhibition (HP:0000734)2.20690785
95Pulmonary infiltrates (HP:0002113)2.18034687
96Acute hepatic failure (HP:0006554)2.17019695
97Hematochezia (HP:0002573)2.16852267
98Premature loss of primary teeth (HP:0006323)2.15189513
99Hypochromic microcytic anemia (HP:0004840)2.14994725
100Panhypogammaglobulinemia (HP:0003139)2.14863168
101Spontaneous hematomas (HP:0007420)2.13516024
102Recurrent bronchitis (HP:0002837)2.12659462
103Keratitis (HP:0000491)2.11804729
104Hypobetalipoproteinemia (HP:0003563)2.11654712
105Urticaria (HP:0001025)2.10527695
106Eosinophilia (HP:0001880)2.09847970
107Abnormality of methionine metabolism (HP:0010901)2.09669077
108Abnormality of the endocardium (HP:0004306)2.09610175
109Lymphopenia (HP:0001888)2.07932098
110Autoimmune hemolytic anemia (HP:0001890)2.06667416
111Autoimmune thrombocytopenia (HP:0001973)2.06142820
112Abnormality of polysaccharide metabolism (HP:0011012)2.04785687
113Abnormality of glycosaminoglycan metabolism (HP:0004371)2.04785687
114Abnormality of mucopolysaccharide metabolism (HP:0011020)2.04785687
115Papilloma (HP:0012740)2.04538389
116Verrucae (HP:0200043)2.04538389
117Glomerulopathy (HP:0100820)2.04491590
118Skin ulcer (HP:0200042)2.02774354
119Leukopenia (HP:0001882)2.02469755
120Polyneuropathy (HP:0001271)2.02099584
121Leukocytosis (HP:0001974)2.01673058
122Hypergammaglobulinemia (HP:0010702)2.01472346
123Pulmonary embolism (HP:0002204)2.01139241
124Abnormality of the pericardium (HP:0001697)1.99578189
125Increased serum ferritin (HP:0003281)1.98304694
126Nephritis (HP:0000123)1.97606115
127Peripheral demyelination (HP:0011096)1.97037989
128Chronic diarrhea (HP:0002028)1.96222627
129IgA deficiency (HP:0002720)1.96163669
130IgG deficiency (HP:0004315)1.95828435
131Abnormality of sulfur amino acid metabolism (HP:0004339)1.95803648
132Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.95602054
133Encephalitis (HP:0002383)1.95496623
134Subacute progressive viral hepatitis (HP:0006572)1.95401648
135Albinism (HP:0001022)1.95369190
136Restrictive lung disease (HP:0002091)1.94991325
137Recurrent lower respiratory tract infections (HP:0002783)1.94784878
138Arthralgia (HP:0002829)1.94768956
139Pathologic fracture (HP:0002756)1.93588210
140Emphysema (HP:0002097)1.92949056
141Conjugated hyperbilirubinemia (HP:0002908)1.92808991
142Abnormality of cells of the lymphoid lineage (HP:0012140)1.91658615
143Duplicated collecting system (HP:0000081)1.91093952
144Hypoalphalipoproteinemia (HP:0003233)1.90520303
145Purpura (HP:0000979)1.89823685
146Fat malabsorption (HP:0002630)1.89753110

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K13.81179851
2MAP3K143.25768679
3BLK3.18410602
4TYK23.03919353
5MAP3K132.90896495
6IRAK32.89233389
7IRAK42.78110707
8ERN12.67089278
9CSF1R2.63162980
10TBK12.50661853
11RIPK42.49020580
12KIT2.38037763
13TGFBR22.15841503
14IKBKB2.10377553
15EPHB12.05968980
16JAK11.98928902
17IKBKE1.90714397
18TAOK31.80869562
19FRK1.75105823
20CLK11.68482426
21CSK1.67319758
22STK101.59764277
23TNK21.58633504
24FES1.55596318
25BTK1.50517931
26CAMK1D1.48412785
27SYK1.45688203
28TAOK11.43216247
29HCK1.41345246
30BMPR21.38321923
31KSR21.38023542
32NEK91.37788362
33JAK31.36559979
34CDK121.35999723
35ZAP701.32750560
36MAPK151.32440687
37PKN11.30687484
38PRPF4B1.29063286
39MAP3K11.27517249
40LYN1.27228155
41FGFR31.24491828
42SIK11.22069620
43GRK61.20100712
44FGFR41.17060375
45MAP3K21.11374543
46ACVR1B1.10428786
47LCK1.08108799
48PIK3CG1.07933369
49FGR1.06076890
50CHUK1.04864608
51STK241.01847464
52ITK1.00405277
53MATK0.96297641
54MAP3K100.93993375
55CAMK1G0.92435332
56BRD40.92396796
57MAP2K30.92195095
58PTK2B0.91595147
59MARK30.91246753
60JAK20.91008369
61PRKCQ0.85852977
62TXK0.85652909
63PIM10.82174594
64STK40.77190613
65TEC0.73758410
66KSR10.71173336
67PTK60.68290920
68MAP2K60.67984015
69EIF2AK20.67937735
70MAP3K110.67247396
71PRKD20.67002019
72ABL10.64959715
73MAP3K90.63158995
74RAF10.62776977
75MOS0.61500356
76LRRK20.60595615
77STK30.60145682
78RPS6KA50.59389600
79TLK10.58981807
80CDC42BPA0.58722281
81YES10.58519888
82MAPK70.58345814
83SIK30.57942716
84MAP3K50.57880209
85STK110.57282471
86FLT30.57082674
87EPHA30.56862208
88MARK20.56209778
89EIF2AK30.56184513
90RPS6KA40.55432211
91MELK0.54787226
92STK390.54716934
93ARAF0.54363976
94NLK0.52230590
95MAP3K60.51840876
96EGFR0.51433427
97CSNK1A1L0.48969615
98CDK30.48842407
99HIPK20.48528985
100GSK3A0.48218956
101MAPK120.47621680
102PRKCD0.47362253
103GRK10.47319360
104PKN20.47025320
105MAP2K40.46373559
106MAP3K70.46119072
107BCKDK0.45809181
108MAP3K30.45316998
109PRKAA20.44259888
110IRAK20.43840966
111MAP2K20.43583515
112SMG10.43506989
113WNK10.42981199
114PDK10.42964217
115TAOK20.42310983
116PDPK10.42075332
117CDK190.41976254
118SIK20.41900240
119MAPK110.41459290
120IRAK10.40329895
121SGK30.39893636
122GRK70.39422900
123FGFR20.39220379
124MET0.37625226
125PRKCZ0.37505644
126ERBB40.37124407
127MAPKAPK50.36407935
128FYN0.36294657
129MAPK40.36174690
130CSNK1G10.34931580
131MAPKAPK20.34047783
132TRPM70.33839245
133TTN0.33669152
134CDK40.33395549
135INSR0.33218792
136SGK20.31029103

Predicted pathways (KEGG)

RankGene SetZ-score
1Staphylococcus aureus infection_Homo sapiens_hsa051503.52197133
2Primary bile acid biosynthesis_Homo sapiens_hsa001202.81330404
3Autoimmune thyroid disease_Homo sapiens_hsa053202.75969887
4B cell receptor signaling pathway_Homo sapiens_hsa046622.72763067
5Complement and coagulation cascades_Homo sapiens_hsa046102.42119327
6NF-kappa B signaling pathway_Homo sapiens_hsa040642.27999398
7Type I diabetes mellitus_Homo sapiens_hsa049402.27425706
8Leishmaniasis_Homo sapiens_hsa051402.07801435
9Osteoclast differentiation_Homo sapiens_hsa043802.00917219
10Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.95955993
11Primary immunodeficiency_Homo sapiens_hsa053401.95482416
12Glycosaminoglycan degradation_Homo sapiens_hsa005311.94085580
13Steroid biosynthesis_Homo sapiens_hsa001001.86081220
14Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.85574464
15Viral myocarditis_Homo sapiens_hsa054161.82755325
16Caffeine metabolism_Homo sapiens_hsa002321.79008053
17Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.69133895
18Toll-like receptor signaling pathway_Homo sapiens_hsa046201.67208565
19Lysosome_Homo sapiens_hsa041421.60868195
20Nitrogen metabolism_Homo sapiens_hsa009101.59751757
21ABC transporters_Homo sapiens_hsa020101.58218853
22Intestinal immune network for IgA production_Homo sapiens_hsa046721.55072128
23Pentose and glucuronate interconversions_Homo sapiens_hsa000401.53460603
24Other glycan degradation_Homo sapiens_hsa005111.51278715
25NOD-like receptor signaling pathway_Homo sapiens_hsa046211.47358263
26Histidine metabolism_Homo sapiens_hsa003401.45879743
27Pertussis_Homo sapiens_hsa051331.45083456
28Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.41887868
29Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.40945505
30Hematopoietic cell lineage_Homo sapiens_hsa046401.40340682
31Fatty acid elongation_Homo sapiens_hsa000621.38468221
32Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.37578643
33Dorso-ventral axis formation_Homo sapiens_hsa043201.34509082
34Measles_Homo sapiens_hsa051621.33515483
35Arginine biosynthesis_Homo sapiens_hsa002201.31473247
36RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.28601761
37Peroxisome_Homo sapiens_hsa041461.27456309
38Malaria_Homo sapiens_hsa051441.26943949
39Tryptophan metabolism_Homo sapiens_hsa003801.24776824
40Tuberculosis_Homo sapiens_hsa051521.23527120
41Drug metabolism - other enzymes_Homo sapiens_hsa009831.18950105
42Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.18097321
43Antigen processing and presentation_Homo sapiens_hsa046121.14017809
44Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.13929679
45Steroid hormone biosynthesis_Homo sapiens_hsa001401.12793464
46Vitamin B6 metabolism_Homo sapiens_hsa007501.11439103
47Chemical carcinogenesis_Homo sapiens_hsa052041.07096056
48Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.03393923
49Apoptosis_Homo sapiens_hsa042101.01970158
50Non-small cell lung cancer_Homo sapiens_hsa052230.97939762
51Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.97928992
52Legionellosis_Homo sapiens_hsa051340.97473730
53Renal cell carcinoma_Homo sapiens_hsa052110.94651889
54Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.92643063
55Platelet activation_Homo sapiens_hsa046110.92330453
56Retinol metabolism_Homo sapiens_hsa008300.92210081
57Influenza A_Homo sapiens_hsa051640.92009661
58Toxoplasmosis_Homo sapiens_hsa051450.92007717
59Leukocyte transendothelial migration_Homo sapiens_hsa046700.91753351
60Selenocompound metabolism_Homo sapiens_hsa004500.89956753
61Folate biosynthesis_Homo sapiens_hsa007900.88096033
62PPAR signaling pathway_Homo sapiens_hsa033200.87909671
63Herpes simplex infection_Homo sapiens_hsa051680.87865057
64Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.86666010
65Graft-versus-host disease_Homo sapiens_hsa053320.85475746
66Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.85160091
67Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.84650549
68beta-Alanine metabolism_Homo sapiens_hsa004100.84341229
69Phagosome_Homo sapiens_hsa041450.84121910
70T cell receptor signaling pathway_Homo sapiens_hsa046600.81699919
71Prolactin signaling pathway_Homo sapiens_hsa049170.81354358
72Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.81286517
73TNF signaling pathway_Homo sapiens_hsa046680.80647286
74Neurotrophin signaling pathway_Homo sapiens_hsa047220.80123958
75Sulfur relay system_Homo sapiens_hsa041220.79056410
76Acute myeloid leukemia_Homo sapiens_hsa052210.78804531
77Shigellosis_Homo sapiens_hsa051310.77183032
78AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.77044035
79Fatty acid degradation_Homo sapiens_hsa000710.76984505
80Chemokine signaling pathway_Homo sapiens_hsa040620.76920751
81Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.76826086
82Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.74371683
83Sphingolipid signaling pathway_Homo sapiens_hsa040710.74174748
84Ether lipid metabolism_Homo sapiens_hsa005650.73902052
85FoxO signaling pathway_Homo sapiens_hsa040680.73782391
86Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.72856699
87Viral carcinogenesis_Homo sapiens_hsa052030.71446176
88Jak-STAT signaling pathway_Homo sapiens_hsa046300.69892511
89Allograft rejection_Homo sapiens_hsa053300.68879703
90Vitamin digestion and absorption_Homo sapiens_hsa049770.67863740
91Systemic lupus erythematosus_Homo sapiens_hsa053220.66893178
92VEGF signaling pathway_Homo sapiens_hsa043700.65667217
93Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.63565699
94Sphingolipid metabolism_Homo sapiens_hsa006000.63250345
95SNARE interactions in vesicular transport_Homo sapiens_hsa041300.62937766
96Rheumatoid arthritis_Homo sapiens_hsa053230.62871312
97Lysine degradation_Homo sapiens_hsa003100.62655219
98Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.61467400
99Hepatitis C_Homo sapiens_hsa051600.61271017
100Hepatitis B_Homo sapiens_hsa051610.61064746
101Salmonella infection_Homo sapiens_hsa051320.60100105
102HIF-1 signaling pathway_Homo sapiens_hsa040660.59586732
103Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.58038293
104Inositol phosphate metabolism_Homo sapiens_hsa005620.57627983
105Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.55582362
106Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.54966115
107Prostate cancer_Homo sapiens_hsa052150.54731166
108One carbon pool by folate_Homo sapiens_hsa006700.54017796
109Fatty acid metabolism_Homo sapiens_hsa012120.53773051
110Insulin resistance_Homo sapiens_hsa049310.53567452
111HTLV-I infection_Homo sapiens_hsa051660.53085979
112Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.52736233
113Pancreatic cancer_Homo sapiens_hsa052120.52352964
114Adipocytokine signaling pathway_Homo sapiens_hsa049200.51827654
115Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.51650903
116Prion diseases_Homo sapiens_hsa050200.50677774
117mTOR signaling pathway_Homo sapiens_hsa041500.50650494
118Phosphatidylinositol signaling system_Homo sapiens_hsa040700.50088118
119Phenylalanine metabolism_Homo sapiens_hsa003600.50038993
120Tyrosine metabolism_Homo sapiens_hsa003500.48435267
121Endocytosis_Homo sapiens_hsa041440.47830964
122Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.47679411
123MAPK signaling pathway_Homo sapiens_hsa040100.47019671
124Colorectal cancer_Homo sapiens_hsa052100.45699736
125Transcriptional misregulation in cancer_Homo sapiens_hsa052020.44931006
126Epstein-Barr virus infection_Homo sapiens_hsa051690.44840985
127Phospholipase D signaling pathway_Homo sapiens_hsa040720.43763702
128Chronic myeloid leukemia_Homo sapiens_hsa052200.43594673
129Endometrial cancer_Homo sapiens_hsa052130.43459685
130Glycerophospholipid metabolism_Homo sapiens_hsa005640.43283013
131Type II diabetes mellitus_Homo sapiens_hsa049300.42320521
132GnRH signaling pathway_Homo sapiens_hsa049120.41999703
133Asthma_Homo sapiens_hsa053100.41346929
134African trypanosomiasis_Homo sapiens_hsa051430.41083928
135Carbohydrate digestion and absorption_Homo sapiens_hsa049730.39758369
136Small cell lung cancer_Homo sapiens_hsa052220.38336129
137Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.36901474
138ErbB signaling pathway_Homo sapiens_hsa040120.36036968
139Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.34896647
140Regulation of autophagy_Homo sapiens_hsa041400.34797993
141Notch signaling pathway_Homo sapiens_hsa043300.33639546
142Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.32930969
143Choline metabolism in cancer_Homo sapiens_hsa052310.32907575
144Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.30909220
145Amoebiasis_Homo sapiens_hsa051460.30066207

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »