SLC16A6

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1melanin biosynthetic process (GO:0042438)6.83928369
2melanin metabolic process (GO:0006582)6.41389672
3secondary metabolite biosynthetic process (GO:0044550)5.37786006
4response to peptidoglycan (GO:0032494)5.18421883
5cellular extravasation (GO:0045123)4.26546602
6detection of molecule of bacterial origin (GO:0032490)4.25438153
7neutrophil activation involved in immune response (GO:0002283)4.06321356
8lipopolysaccharide-mediated signaling pathway (GO:0031663)3.99679369
9positive regulation by symbiont of host defense response (GO:0052509)3.97966626
10modulation by symbiont of host defense response (GO:0052031)3.97966626
11modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.97966626
12modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.97966626
13positive regulation by organism of defense response of other organism involved in symbiotic interact3.97966626
14modulation by symbiont of host immune response (GO:0052553)3.97966626
15DNA replication checkpoint (GO:0000076)3.91122161
16glycosphingolipid catabolic process (GO:0046479)3.84533847
17cellular response to thyroid hormone stimulus (GO:0097067)3.78104629
18positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.72885065
19pigment cell differentiation (GO:0050931)3.69066413
20regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.64488428
21oligosaccharide catabolic process (GO:0009313)3.55672501
22antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.52581928
23antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.52581928
24melanocyte differentiation (GO:0030318)3.49858073
25regulation of vitamin D biosynthetic process (GO:0060556)3.41444552
26regulation of mast cell degranulation (GO:0043304)3.38950899
27glycolipid catabolic process (GO:0019377)3.38459940
28monoubiquitinated protein deubiquitination (GO:0035520)3.35188511
29GMP metabolic process (GO:0046037)3.33068730
30mitotic metaphase plate congression (GO:0007080)3.31796530
31regulation of spindle organization (GO:0090224)3.31405803
32positive regulation of membrane protein ectodomain proteolysis (GO:0051044)3.30450614
33macrophage activation (GO:0042116)3.30392399
34granulocyte activation (GO:0036230)3.25802296
35purine nucleobase biosynthetic process (GO:0009113)3.23997098
36positive regulation of mast cell activation (GO:0033005)3.22852500
37antigen processing and presentation of endogenous antigen (GO:0019883)3.21676627
38regulation of mast cell activation involved in immune response (GO:0033006)3.19094826
39detection of external biotic stimulus (GO:0098581)3.18819355
40cellular response to arsenic-containing substance (GO:0071243)3.16302122
41regulation of rhodopsin mediated signaling pathway (GO:0022400)3.16186794
42positive regulation of chemokine biosynthetic process (GO:0045080)3.15649009
43neutrophil mediated immunity (GO:0002446)3.15225529
44macrophage activation involved in immune response (GO:0002281)3.13307611
45germinal center formation (GO:0002467)3.12655062
46response to thyroid hormone (GO:0097066)3.11930166
47positive regulation of chromosome segregation (GO:0051984)3.11130513
48regulation of leukocyte degranulation (GO:0043300)3.10928221
49folic acid metabolic process (GO:0046655)3.05179660
50nucleobase biosynthetic process (GO:0046112)3.04092152
51rhodopsin mediated signaling pathway (GO:0016056)3.03543062
52positive regulation of B cell differentiation (GO:0045579)3.02781615
53protein localization to kinetochore (GO:0034501)3.02129462
54regulation of mast cell activation (GO:0033003)3.01956557
55T-helper 1 type immune response (GO:0042088)3.01877443
56myeloid cell activation involved in immune response (GO:0002275)3.00953000
57mitotic nuclear envelope disassembly (GO:0007077)3.00623892
58regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.00542911
59detection of other organism (GO:0098543)3.00387826
60positive regulation of gamma-delta T cell activation (GO:0046645)3.00140034
61regulation of interferon-beta biosynthetic process (GO:0045357)2.99565453
62positive regulation of leukocyte degranulation (GO:0043302)2.99167146
63protein localization to chromosome, centromeric region (GO:0071459)2.98507803
64neutrophil activation (GO:0042119)2.97394194
65ceramide catabolic process (GO:0046514)2.97062500
66leukocyte aggregation (GO:0070486)2.96914589
67positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.96742600
68regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.95743475
69regulation of B cell receptor signaling pathway (GO:0050855)2.91920408
70vitamin transmembrane transport (GO:0035461)2.91810292
71detection of biotic stimulus (GO:0009595)2.90933007
72regulation of T-helper 2 cell differentiation (GO:0045628)2.88789044
73neutrophil chemotaxis (GO:0030593)2.88580734
74response to protozoan (GO:0001562)2.86886209
75positive thymic T cell selection (GO:0045059)2.85296371
76regulation of myeloid leukocyte mediated immunity (GO:0002886)2.84031929
77iron ion import (GO:0097286)2.83533178
78positive regulation of mast cell degranulation (GO:0043306)2.82957312
79positive regulation of mast cell activation involved in immune response (GO:0033008)2.82957312
80positive regulation of NF-kappaB import into nucleus (GO:0042346)2.82671817
81protoporphyrinogen IX metabolic process (GO:0046501)2.82273895
82osteoclast differentiation (GO:0030316)2.82214881
83protein localization to endosome (GO:0036010)2.81248331
84response to muramyl dipeptide (GO:0032495)2.81052890
85positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.80741700
86neutrophil migration (GO:1990266)2.80163705
87positive regulation of interleukin-8 biosynthetic process (GO:0045416)2.79094481
88respiratory burst (GO:0045730)2.77709276
89nuclear envelope disassembly (GO:0051081)2.76698044
90membrane disassembly (GO:0030397)2.76698044
91pre-miRNA processing (GO:0031054)2.76537592
92DNA replication initiation (GO:0006270)2.76408860
93response to laminar fluid shear stress (GO:0034616)2.76262686
94negative regulation of granulocyte differentiation (GO:0030853)2.75527604
95regulation of chemokine biosynthetic process (GO:0045073)2.74883680
96ribosome assembly (GO:0042255)2.74789723
97regulation of nitric-oxide synthase biosynthetic process (GO:0051769)2.74688291
98regulation of membrane protein ectodomain proteolysis (GO:0051043)2.74680143
99negative regulation of cytokine production involved in immune response (GO:0002719)2.74374744
100megakaryocyte development (GO:0035855)2.72257096
1013-UTR-mediated mRNA stabilization (GO:0070935)2.71950807
102regulation of histone H3-K27 methylation (GO:0061085)2.71832367
103pinocytosis (GO:0006907)2.71424704
104NIK/NF-kappaB signaling (GO:0038061)2.70974638
105maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.70273176
106defense response to protozoan (GO:0042832)2.70153162
107amino sugar catabolic process (GO:0046348)2.69071991
108protoporphyrinogen IX biosynthetic process (GO:0006782)2.68099300
109microglial cell activation (GO:0001774)2.68086319
110metaphase plate congression (GO:0051310)2.67669093
111regulation of gamma-delta T cell activation (GO:0046643)2.67612213
112adaptation of signaling pathway (GO:0023058)2.67306933
113retinal cone cell development (GO:0046549)2.66686709
114positive regulation of erythrocyte differentiation (GO:0045648)2.66574402
115positive regulation of cellular amide metabolic process (GO:0034250)2.64819689
116N-acetylneuraminate metabolic process (GO:0006054)2.63449133
117negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.63338267
118negative regulation of cell killing (GO:0031342)2.63338267
119negative regulation of phagocytosis (GO:0050765)2.60712554
120regulation of nuclear cell cycle DNA replication (GO:0033262)2.60582927
121regulation of translation in response to stress (GO:0043555)2.60557234
122DNA strand elongation involved in DNA replication (GO:0006271)2.59942880
123regulation of erythrocyte differentiation (GO:0045646)2.59860495
124chaperone mediated protein folding requiring cofactor (GO:0051085)2.59850568
125mitotic sister chromatid segregation (GO:0000070)2.59659831
126embryonic hemopoiesis (GO:0035162)2.59463321
127myeloid leukocyte mediated immunity (GO:0002444)2.58801238
128negative regulation of interleukin-12 production (GO:0032695)2.58441750
129antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.57159935
130erythrocyte maturation (GO:0043249)2.56838209
131regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.56672142
132detection of bacterium (GO:0016045)2.56273234
133myeloid dendritic cell differentiation (GO:0043011)2.55668187
134regulation of exit from mitosis (GO:0007096)2.55668046
135negative regulation of histone methylation (GO:0031061)2.55443546
136cellular response to molecule of bacterial origin (GO:0071219)2.54957824
137positive regulation of odontogenesis (GO:0042482)2.54894771
138cellular response to lipopolysaccharide (GO:0071222)2.53231151
139regulation of mononuclear cell migration (GO:0071675)2.53085222
140regulation of RNA export from nucleus (GO:0046831)2.53081614
141myeloid leukocyte activation (GO:0002274)2.52616470
142nuclear envelope organization (GO:0006998)2.52459354
143positive regulation of heat generation (GO:0031652)2.51815133
144DNA strand elongation (GO:0022616)2.49955685
145tolerance induction (GO:0002507)2.49700171
146immunoglobulin mediated immune response (GO:0016064)2.48315963
147regulation of gamma-delta T cell differentiation (GO:0045586)2.47994739
148regulation of mitotic spindle organization (GO:0060236)2.47936622
149positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.45450250
150positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.45450250
151positive regulation of mitotic sister chromatid separation (GO:1901970)2.45450250
152telomere maintenance via semi-conservative replication (GO:0032201)2.44693121
153ribosome biogenesis (GO:0042254)2.44423825
154response to host (GO:0075136)2.43894950
155response to host defenses (GO:0052200)2.43894950
156response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.43894950
157DNA damage response, signal transduction resulting in transcription (GO:0042772)2.43040579
158DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla2.41637661
159regulation of granulocyte differentiation (GO:0030852)2.41149700
160positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.40753434
161intestinal epithelial cell development (GO:0060576)2.40469930
162negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.40125081
163mannose metabolic process (GO:0006013)2.40109977
164regulation of nucleobase-containing compound transport (GO:0032239)2.39327428
165lipopolysaccharide biosynthetic process (GO:0009103)2.38535025
166regulation of interferon-gamma-mediated signaling pathway (GO:0060334)2.38049858
167regulation of response to interferon-gamma (GO:0060330)2.37624173
168folic acid-containing compound biosynthetic process (GO:0009396)2.37526568
169telomere maintenance via recombination (GO:0000722)2.37180683
170sister chromatid segregation (GO:0000819)2.36161073
171B cell receptor signaling pathway (GO:0050853)2.35511542
172mitotic chromosome condensation (GO:0007076)2.35300583
173response to host immune response (GO:0052572)2.35059339
174response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.35059339
175mitotic sister chromatid cohesion (GO:0007064)2.32258775
176protein localization to chromosome (GO:0034502)2.31269068

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.56761479
2FOXM1_23109430_ChIP-Seq_U2OS_Human3.87994809
3Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse3.14970104
4MYC_22102868_ChIP-Seq_BL_Human3.12817950
5EGR1_19374776_ChIP-ChIP_THP-1_Human2.78497617
6RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.69904965
7EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.65005217
8E2F4_17652178_ChIP-ChIP_JURKAT_Human2.55343604
9STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.55153900
10IRF8_22096565_ChIP-ChIP_GC-B_Human2.48802671
11MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.45644802
12IRF8_21731497_ChIP-ChIP_J774_Mouse2.33036266
13SCL_19346495_ChIP-Seq_HPC-7_Human2.30528121
14VDR_21846776_ChIP-Seq_THP-1_Human2.28252410
15FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.25508621
16SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.17645397
17VDR_24787735_ChIP-Seq_THP-1_Human2.08740413
18MYB_21317192_ChIP-Seq_ERMYB_Mouse2.07738427
19VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.00005094
20* MYC_18555785_ChIP-Seq_MESCs_Mouse1.99547220
21STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.96321636
22SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.92178223
23NOTCH1_21737748_ChIP-Seq_TLL_Human1.91643266
24KDM2B_26808549_Chip-Seq_SUP-B15_Human1.91209335
25NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.88094000
26BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.87313248
27CIITA_25753668_ChIP-Seq_RAJI_Human1.86008420
28ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.84771207
29SPI1_23547873_ChIP-Seq_NB4_Human1.84160926
30SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.83347551
31* PU_27001747_Chip-Seq_BMDM_Mouse1.76593709
32* E2F1_21310950_ChIP-Seq_MCF-7_Human1.75291019
33* RUNX_20019798_ChIP-Seq_JUKART_Human1.75010829
34IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.70046729
35SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.69304551
36IRF8_27001747_Chip-Seq_BMDM_Mouse1.68286378
37MYB_26560356_Chip-Seq_TH1_Human1.67496461
38TCF7_22412390_ChIP-Seq_EML_Mouse1.65317706
39SMAD_19615063_ChIP-ChIP_OVARY_Human1.64171249
40BRD4_27068464_Chip-Seq_AML-cells_Mouse1.63993613
41VDR_23849224_ChIP-Seq_CD4+_Human1.63750823
42ELK3_25401928_ChIP-Seq_HUVEC_Human1.63560229
43RUNX1_22412390_ChIP-Seq_EML_Mouse1.63510839
44RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.61464516
45TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.60773803
46* MYB_26560356_Chip-Seq_TH2_Human1.59037382
47TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.59003030
48MAF_26560356_Chip-Seq_TH1_Human1.58615376
49NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.58381338
50FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.57884017
51* NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.57679318
52FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.57600640
53MYC_19079543_ChIP-ChIP_MESCs_Mouse1.56470040
54CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.56466116
55NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.53558906
56FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.53510557
57ETS1_20019798_ChIP-Seq_JURKAT_Human1.52427257
58GATA1_22025678_ChIP-Seq_K562_Human1.51071469
59PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.49361481
60* UTX_26944678_Chip-Seq_JUKART_Human1.48881327
61KDM5A_27292631_Chip-Seq_BREAST_Human1.48451145
62* GATA1_22383799_ChIP-Seq_G1ME_Mouse1.44867950
63* E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.43847305
64EST1_17652178_ChIP-ChIP_JURKAT_Human1.42265640
65CREB1_15753290_ChIP-ChIP_HEK293T_Human1.42178228
66MYC_18358816_ChIP-ChIP_MESCs_Mouse1.41396039
67IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.41334382
68TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.41301392
69* ESR2_21235772_ChIP-Seq_MCF-7_Human1.40012333
70GATA2_21666600_ChIP-Seq_HMVEC_Human1.39682800
71JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.39186539
72* MYC_19030024_ChIP-ChIP_MESCs_Mouse1.37706093
73VDR_24763502_ChIP-Seq_THP-1_Human1.36538699
74CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.36150779
75KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.35884199
76* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.34660650
77FOXP3_21729870_ChIP-Seq_TREG_Human1.34511711
78GATA1_19941827_ChIP-Seq_MEL_Mouse1.33794208
79TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.32336710
80MYCN_18555785_ChIP-Seq_MESCs_Mouse1.32027686
81AR_21909140_ChIP-Seq_LNCAP_Human1.30688052
82STAT4_19710469_ChIP-ChIP_TH1__Mouse1.29519334
83PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.29085636
84NELFA_20434984_ChIP-Seq_ESCs_Mouse1.26956273
85CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.26620227
86GATA2_22383799_ChIP-Seq_G1ME_Mouse1.26393307
87* KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.25814834
88PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.25507503
89GABP_19822575_ChIP-Seq_HepG2_Human1.25008757
90CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.23338696
91ERG_20887958_ChIP-Seq_HPC-7_Mouse1.23040229
92HOXB4_20404135_ChIP-ChIP_EML_Mouse1.23011346
93XRN2_22483619_ChIP-Seq_HELA_Human1.22314461
94LXR_22292898_ChIP-Seq_THP-1_Human1.21918848
95MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.19684678
96STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.18337656
97GABP_17652178_ChIP-ChIP_JURKAT_Human1.17754734
98CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.17420108
99TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.17095361
100ELF1_17652178_ChIP-ChIP_JURKAT_Human1.16991974
101TFEB_21752829_ChIP-Seq_HELA_Human1.16920636
102MAF_26560356_Chip-Seq_TH2_Human1.15409065
103* SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.15408295
104PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.15226767
105KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.13010697
106NANOG_18555785_ChIP-Seq_MESCs_Mouse1.11849366
107SPI1_23127762_ChIP-Seq_K562_Human1.11626236
108GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.10139670
109RACK7_27058665_Chip-Seq_MCF-7_Human1.09494434
110CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.08312676
111CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.08300047
112RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.07335891
113RARG_19884340_ChIP-ChIP_MEFs_Mouse1.06956217
114UBF1/2_26484160_Chip-Seq_HMECs_Human1.06073136
115POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.05740844
116* SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.05650697
117MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.05364611
118SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.04829920
119SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.04829920
120* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.04745202
121ZNF263_19887448_ChIP-Seq_K562_Human1.04647745
122KLF4_18555785_ChIP-Seq_MESCs_Mouse1.03513443
123E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.03400579
124GATA3_27048872_Chip-Seq_THYMUS_Human1.03301751
125* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.02862805
126* MITF_21258399_ChIP-Seq_MELANOMA_Human1.01931941
127P300_27058665_Chip-Seq_ZR-75-30cells_Human1.01433574
128* KDM2B_26808549_Chip-Seq_JURKAT_Human1.01381832
129KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.01198333
130SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.00980329
131PU.1_20513432_ChIP-Seq_Bcells_Mouse1.00836863
132E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.00773106
133* KDM2B_26808549_Chip-Seq_DND41_Human0.98913492
134CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.98399282
135TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.97828072
136JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.97573407
137LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.96895486
138JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.96706481
139* ESR1_20079471_ChIP-ChIP_T-47D_Human0.96663830
140BP1_19119308_ChIP-ChIP_Hs578T_Human0.96486182
141DCP1A_22483619_ChIP-Seq_HELA_Human0.96412675
142THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.95161212
143NCOR1_26117541_ChIP-Seq_K562_Human0.94495251
144TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.92433898
145GATA1_19941826_ChIP-Seq_K562_Human0.92014566
146CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.91839396

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003136_yellow_coat_color3.95632390
2MP0005171_absent_coat_pigmentation3.87929311
3MP0000372_irregular_coat_pigmentation3.84233765
4MP0003693_abnormal_embryo_hatching3.49757777
5MP0008057_abnormal_DNA_replication3.42997294
6MP0002877_abnormal_melanocyte_morpholog2.93711654
7MP0004381_abnormal_hair_follicle2.86822896
8MP0003111_abnormal_nucleus_morphology2.83407257
9MP0000371_diluted_coat_color2.77873446
10MP0002396_abnormal_hematopoietic_system2.63056909
11MP0005408_hypopigmentation2.60827814
12MP0005671_abnormal_response_to2.58917085
13MP0010094_abnormal_chromosome_stability2.55720255
14MP0003656_abnormal_erythrocyte_physiolo2.44600751
15MP0003077_abnormal_cell_cycle2.42403887
16MP0005075_abnormal_melanosome_morpholog2.42373394
17MP0003303_peritoneal_inflammation2.41591160
18MP0003011_delayed_dark_adaptation2.35884099
19MP0001835_abnormal_antigen_presentation2.35818779
20MP0009333_abnormal_splenocyte_physiolog2.24735198
21MP0000569_abnormal_digit_pigmentation2.20650410
22MP0001800_abnormal_humoral_immune2.17695955
23MP0005464_abnormal_platelet_physiology2.17621043
24MP0005257_abnormal_intraocular_pressure2.15287970
25MP0010307_abnormal_tumor_latency2.13181169
26MP0002398_abnormal_bone_marrow2.05697592
27MP0005058_abnormal_lysosome_morphology1.98608655
28MP0001545_abnormal_hematopoietic_system1.97350883
29MP0005397_hematopoietic_system_phenotyp1.97350883
30MP0009840_abnormal_foam_cell1.91787982
31MP0002452_abnormal_antigen_presenting1.89969038
32MP0000689_abnormal_spleen_morphology1.86936659
33MP0005409_darkened_coat_color1.86775862
34MP0008007_abnormal_cellular_replicative1.84238363
35MP0002723_abnormal_immune_serum1.83917002
36MP0004808_abnormal_hematopoietic_stem1.83816078
37MP0002722_abnormal_immune_system1.83672287
38MP0003763_abnormal_thymus_physiology1.81701450
39MP0002420_abnormal_adaptive_immunity1.80443910
40MP0001819_abnormal_immune_cell1.79248238
41MP0006082_CNS_inflammation1.78853264
42MP0004957_abnormal_blastocyst_morpholog1.78792081
43MP0002998_abnormal_bone_remodeling1.77333295
44MP0008058_abnormal_DNA_repair1.76629002
45MP0000343_altered_response_to1.74517221
46MP0000490_abnormal_crypts_of1.72413628
47MP0003436_decreased_susceptibility_to1.71256353
48MP0000716_abnormal_immune_system1.69905607
49MP0002419_abnormal_innate_immunity1.68415651
50MP0005000_abnormal_immune_tolerance1.67578855
51MP0002095_abnormal_skin_pigmentation1.67094081
52MP0003191_abnormal_cellular_cholesterol1.64085080
53MP0003172_abnormal_lysosome_physiology1.61483492
54MP0002405_respiratory_system_inflammati1.60987442
55MP0002429_abnormal_blood_cell1.58335134
56MP0000465_gastrointestinal_hemorrhage1.57274213
57MP0005025_abnormal_response_to1.55504272
58MP0000685_abnormal_immune_system1.55390873
59MP0004264_abnormal_extraembryonic_tissu1.55122688
60MP0005387_immune_system_phenotype1.53649014
61MP0001790_abnormal_immune_system1.53649014
62MP0002075_abnormal_coat/hair_pigmentati1.51393489
63MP0005310_abnormal_salivary_gland1.48114798
64MP0000703_abnormal_thymus_morphology1.47956441
65MP0003300_gastrointestinal_ulcer1.47769835
66MP0001873_stomach_inflammation1.45507868
67MP0005551_abnormal_eye_electrophysiolog1.42392115
68MP0005083_abnormal_biliary_tract1.39440465
69MP0001764_abnormal_homeostasis1.38997688
70MP0005076_abnormal_cell_differentiation1.38194862
71MP0000604_amyloidosis1.37799438
72MP0003075_altered_response_to1.37212428
73MP0000350_abnormal_cell_proliferation1.33744433
74MP0009764_decreased_sensitivity_to1.33450502
75MP0001845_abnormal_inflammatory_respons1.33170013
76MP0001186_pigmentation_phenotype1.31427859
77MP0010155_abnormal_intestine_physiology1.30754846
78MP0003806_abnormal_nucleotide_metabolis1.30399756
79MP0009785_altered_susceptibility_to1.30386197
80MP0009278_abnormal_bone_marrow1.28255871
81MP0005174_abnormal_tail_pigmentation1.27614910
82MP0003453_abnormal_keratinocyte_physiol1.25764244
83MP0003183_abnormal_peptide_metabolism1.23799059
84MP0001324_abnormal_eye_pigmentation1.23486192
85MP0004147_increased_porphyrin_level1.21824084
86MP0004947_skin_inflammation1.21499737
87MP0003690_abnormal_glial_cell1.15139127
88MP0002019_abnormal_tumor_incidence1.14637789
89MP0005451_abnormal_body_composition1.13036390
90MP0005167_abnormal_blood-brain_barrier1.12981196
91MP0001730_embryonic_growth_arrest1.12138105
92MP0002166_altered_tumor_susceptibility1.10796739
93MP0001853_heart_inflammation1.10197979
94MP0003866_abnormal_defecation1.09569284
95MP0005166_decreased_susceptibility_to1.06542399
96MP0005164_abnormal_response_to1.06321939
97MP0006054_spinal_hemorrhage1.05774230
98MP0000313_abnormal_cell_death1.01976573
99MP0008004_abnormal_stomach_pH1.00932653
100MP0008469_abnormal_protein_level0.99379232
101MP0002148_abnormal_hypersensitivity_rea0.97424819
102MP0003828_pulmonary_edema0.96100724
103MP0001851_eye_inflammation0.95205896
104MP0000858_altered_metastatic_potential0.94690460
105MP0000609_abnormal_liver_physiology0.91846468
106MP0000920_abnormal_myelination0.91220354
107MP0002139_abnormal_hepatobiliary_system0.90303896
108MP0002928_abnormal_bile_duct0.88486040
109MP0010352_gastrointestinal_tract_polyps0.87788689
110MP0005380_embryogenesis_phenotype0.87476430
111MP0001672_abnormal_embryogenesis/_devel0.87476430
112MP0002090_abnormal_vision0.87026022
113MP0002086_abnormal_extraembryonic_tissu0.86970321
114MP0003984_embryonic_growth_retardation0.86606352
115MP0005253_abnormal_eye_physiology0.85728037
116MP0003718_maternal_effect0.84165475
117MP0002089_abnormal_postnatal_growth/wei0.84103013
118MP0002088_abnormal_embryonic_growth/wei0.83444053
119MP0003786_premature_aging0.83031016
120MP0003091_abnormal_cell_migration0.82990677
121MP0003221_abnormal_cardiomyocyte_apopto0.82545071
122MP0005248_abnormal_Harderian_gland0.81417882
123MP0001697_abnormal_embryo_size0.81285511
124MP0004233_abnormal_muscle_weight0.79718082
125MP0003448_altered_tumor_morphology0.79535777
126MP0000015_abnormal_ear_pigmentation0.78315062
127MP0002080_prenatal_lethality0.77758338
128MP0004185_abnormal_adipocyte_glucose0.77530302
129MP0002006_tumorigenesis0.77449383
130MP0004883_abnormal_blood_vessel0.75972279
131MP0001666_abnormal_nutrient_absorption0.75931653
132MP0001849_ear_inflammation0.74519645
133MP0005621_abnormal_cell_physiology0.73839029
134MP0001986_abnormal_taste_sensitivity0.73620130
135MP0003795_abnormal_bone_structure0.72596726
136MP0003724_increased_susceptibility_to0.72533840
137MP0008260_abnormal_autophagy0.72297322
138MP0002254_reproductive_system_inflammat0.71310125
139MP0000598_abnormal_liver_morphology0.70993689
140MP0004510_myositis0.70825585
141MP0005197_abnormal_uvea_morphology0.70628749
142MP0001533_abnormal_skeleton_physiology0.70546061
143MP0005377_hearing/vestibular/ear_phenot0.68542007
144MP0003878_abnormal_ear_physiology0.68542007
145MP0010234_abnormal_vibrissa_follicle0.67067627

Predicted human phenotypes

RankGene SetZ-score
1Ocular albinism (HP:0001107)5.26202007
2Congenital stationary night blindness (HP:0007642)5.17485265
3Aplasia/Hypoplasia of the fovea (HP:0008060)4.59164136
4Hypoplasia of the fovea (HP:0007750)4.59164136
5Bony spicule pigmentary retinopathy (HP:0007737)4.46109459
6Iris hypopigmentation (HP:0007730)4.35676863
7Loss of speech (HP:0002371)4.28599466
8Pustule (HP:0200039)4.15536829
9Blue irides (HP:0000635)4.04424646
10Aplasia/Hypoplasia of the macula (HP:0008059)4.01717169
11Absent rod-and cone-mediated responses on ERG (HP:0007688)3.86657322
12Abnormal rod and cone electroretinograms (HP:0008323)3.75205632
13Birth length less than 3rd percentile (HP:0003561)3.73994199
14Aplasia/Hypoplasia affecting the retina (HP:0008061)3.68615436
15Recurrent bacterial skin infections (HP:0005406)3.67977350
16Recurrent abscess formation (HP:0002722)3.67402219
17Abnormality of the fovea (HP:0000493)3.58708881
18Pigmentary retinal degeneration (HP:0001146)3.47611538
19Eczematoid dermatitis (HP:0000976)3.43148271
20IgM deficiency (HP:0002850)3.40274625
21Abnormality of the fingertips (HP:0001211)3.37640877
22Abnormality of the heme biosynthetic pathway (HP:0010472)3.33973943
23White forelock (HP:0002211)3.26099337
24Pendular nystagmus (HP:0012043)3.22939509
25Abnormality of mucopolysaccharide metabolism (HP:0011020)3.10978066
26Abnormality of polysaccharide metabolism (HP:0011012)3.10978066
27Abnormality of glycosaminoglycan metabolism (HP:0004371)3.10978066
28Orchitis (HP:0100796)3.09338315
29Poikilocytosis (HP:0004447)3.06051332
30Recurrent fungal infections (HP:0002841)3.04535466
31Optic neuritis (HP:0100653)2.98928586
32Retrobulbar optic neuritis (HP:0100654)2.98928586
33Recurrent viral infections (HP:0004429)2.95021939
34Mucopolysacchariduria (HP:0008155)2.95012939
35Urinary glycosaminoglycan excretion (HP:0003541)2.95012939
36Petechiae (HP:0000967)2.93833825
37Neurofibrillary tangles (HP:0002185)2.93753244
38Fatigue (HP:0012378)2.86918192
39Myocardial infarction (HP:0001658)2.84145849
40Patchy hypopigmentation of hair (HP:0011365)2.80680999
41Stomatitis (HP:0010280)2.75983296
42Inflammation of the large intestine (HP:0002037)2.74486239
43Disinhibition (HP:0000734)2.73718538
44Abnormal platelet function (HP:0011869)2.73314415
45Impaired platelet aggregation (HP:0003540)2.73314415
46Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.71820048
47Colitis (HP:0002583)2.69130204
48Systemic lupus erythematosus (HP:0002725)2.67277674
49Prolonged bleeding time (HP:0003010)2.65973838
50Gastrointestinal inflammation (HP:0004386)2.62105194
51Attenuation of retinal blood vessels (HP:0007843)2.61475389
52Cerebral inclusion bodies (HP:0100314)2.60500534
53Entropion (HP:0000621)2.59421352
54Generalized hypopigmentation of hair (HP:0011358)2.57531237
55Hypopigmentation of the fundus (HP:0007894)2.55472127
56Amyloidosis (HP:0011034)2.52182473
57Vertebral compression fractures (HP:0002953)2.47699767
58Increased neuronal autofluorescent lipopigment (HP:0002074)2.45945760
59Recurrent skin infections (HP:0001581)2.45149139
60Retinal atrophy (HP:0001105)2.44460652
61Increased cerebral lipofuscin (HP:0011813)2.43660440
62Abnormal delayed hypersensitivity skin test (HP:0002963)2.42097242
63Generalized hypopigmentation (HP:0007513)2.41346543
64Abnormality of T cell physiology (HP:0011840)2.39255275
65Recurrent gram-negative bacterial infections (HP:0005420)2.38514076
66Achilles tendon contracture (HP:0001771)2.38421663
67Polycythemia (HP:0001901)2.36507246
68Myelodysplasia (HP:0002863)2.35717708
69Neuronal loss in central nervous system (HP:0002529)2.35117283
70Recurrent cutaneous fungal infections (HP:0011370)2.34976935
71Chronic mucocutaneous candidiasis (HP:0002728)2.34976935
72Vacuolated lymphocytes (HP:0001922)2.33919558
73Thrombocytosis (HP:0001894)2.32984359
74Abnormality of liposaccharide metabolism (HP:0010968)2.30698879
75Abnormality of glycosphingolipid metabolism (HP:0004343)2.30698879
76Abnormality of glycolipid metabolism (HP:0010969)2.30698879
77Lymphopenia (HP:0001888)2.29651630
78Glomerulonephritis (HP:0000099)2.28511020
79Progressive visual loss (HP:0000529)2.28398833
80Chronic otitis media (HP:0000389)2.28235021
81Purpura (HP:0000979)2.27198304
82Freckling (HP:0001480)2.25892460
83Autoimmune thrombocytopenia (HP:0001973)2.25283438
84Obstructive lung disease (HP:0006536)2.24402843
85Chronic obstructive pulmonary disease (HP:0006510)2.24402843
86Photophobia (HP:0000613)2.24279617
87Increased serum ferritin (HP:0003281)2.23061273
88Mediastinal lymphadenopathy (HP:0100721)2.22476574
89Dyschromatopsia (HP:0007641)2.21841123
90Slow saccadic eye movements (HP:0000514)2.20979742
91Epistaxis (HP:0000421)2.20629994
92Urethral obstruction (HP:0000796)2.20218926
93Prominent nose (HP:0000448)2.19594786
94Type II diabetes mellitus (HP:0005978)2.18931512
95Abnormality of cells of the lymphoid lineage (HP:0012140)2.18406326
96Apathy (HP:0000741)2.18027547
97Granulocytopenia (HP:0001913)2.17669385
98Abnormality of macrophages (HP:0004311)2.16669106
99Acanthocytosis (HP:0001927)2.14588305
100Cellulitis (HP:0100658)2.14442135
101Global brain atrophy (HP:0002283)2.13145989
102Abnormality of the Achilles tendon (HP:0005109)2.12880911
103Hypochromic anemia (HP:0001931)2.12697869
104Meningitis (HP:0001287)2.12683598
105Nuclear cataract (HP:0100018)2.12344852
106Diminished motivation (HP:0000745)2.11478206
107Elevated erythrocyte sedimentation rate (HP:0003565)2.10867090
108Pathologic fracture (HP:0002756)2.10660211
109Mutism (HP:0002300)2.10374014
110Abnormality of macular pigmentation (HP:0008002)2.09474942
111Abnormality of T cells (HP:0002843)2.08132211
112Breast hypoplasia (HP:0003187)2.07801987
113Albinism (HP:0001022)2.06762010
114Reticulocytosis (HP:0001923)2.06735976
115Supranuclear gaze palsy (HP:0000605)2.05967912
116Chorioretinal atrophy (HP:0000533)2.05636000
117Dysostosis multiplex (HP:0000943)2.05301025
118Myositis (HP:0100614)2.05296687
119Leukopenia (HP:0001882)2.04624898
120Lymphoma (HP:0002665)2.04388749
121J-shaped sella turcica (HP:0002680)2.04339401
122Interstitial pulmonary disease (HP:0006530)2.04274588
123Cheilitis (HP:0100825)2.02691436
124Bone marrow hypocellularity (HP:0005528)2.02594368
125Subacute progressive viral hepatitis (HP:0006572)2.01586177
126Central scotoma (HP:0000603)2.01406828
127Encephalitis (HP:0002383)2.01260168
128Acute myeloid leukemia (HP:0004808)2.00364854
129Increased IgE level (HP:0003212)2.00071301
130Polyneuropathy (HP:0001271)1.98657039
131Spontaneous hematomas (HP:0007420)1.97993201
132Abnormality of chromosome stability (HP:0003220)1.97561171
133Hematochezia (HP:0002573)1.97337478
134Pulmonary infiltrates (HP:0002113)1.96577420
135Panhypogammaglobulinemia (HP:0003139)1.96368464
136Abnormality of the vasculature of the conjunctiva (HP:0008054)1.96191108
137Vasculitis (HP:0002633)1.95814450
138Progressive neurologic deterioration (HP:0002344)1.95430373
139Chronic diarrhea (HP:0002028)1.94575018
140Abnormality of the periventricular white matter (HP:0002518)1.93683216
141Abnormality of the preputium (HP:0100587)1.93231175
142Gingivitis (HP:0000230)1.91896992
143Abnormality of lateral ventricle (HP:0030047)1.91035519
144Poikiloderma (HP:0001029)1.90788376
145Posterior subcapsular cataract (HP:0007787)1.89990111
146Arterial thrombosis (HP:0004420)1.89689679
147Cone-rod dystrophy (HP:0000548)1.89413598
148T lymphocytopenia (HP:0005403)1.89035783
149Macular degeneration (HP:0000608)1.87205665
150Asymmetric septal hypertrophy (HP:0001670)1.86150830
151Scotoma (HP:0000575)1.86143312
152Upper motor neuron abnormality (HP:0002127)1.84542999
153Premature graying of hair (HP:0002216)1.84415908
154Acute lymphatic leukemia (HP:0006721)1.84244429
155Constricted visual fields (HP:0001133)1.84132991
156Recurrent sinusitis (HP:0011108)1.83681761
157Urticaria (HP:0001025)1.81838934
158Facial hemangioma (HP:0000329)1.81775361
159Personality changes (HP:0000751)1.81176527
160Hepatosplenomegaly (HP:0001433)1.80093802
161B lymphocytopenia (HP:0010976)1.79316348
162Abnormality of B cell number (HP:0010975)1.79316348
163Keratoconjunctivitis sicca (HP:0001097)1.79218197
164Gingival bleeding (HP:0000225)1.76545685
165Axonal loss (HP:0003447)1.74413014
166Hemoptysis (HP:0002105)1.74399592
167Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.73866073
168Episodic fever (HP:0001954)1.73488122
169Abnormality of iron homeostasis (HP:0011031)1.69304339
170Chest pain (HP:0100749)1.69304330
171Gastrointestinal infarctions (HP:0005244)1.68852874
172Thoracic kyphosis (HP:0002942)1.68599918
173Bilateral sensorineural hearing impairment (HP:0008619)1.68200996
174Dementia (HP:0000726)1.66095415

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PDK24.17974317
2MAP4K13.75915033
3TAOK33.25922136
4NEK22.90649146
5MAP3K32.65953902
6EEF2K2.51278809
7PRPF4B2.44855861
8TXK2.41840923
9CDK122.35413528
10STK162.29783077
11MARK32.25627477
12IRAK32.13244668
13TGFBR22.10755440
14BUB11.93323816
15BMPR21.92846526
16TAOK21.87752555
17FGR1.84060836
18STK101.83677285
19TYK21.83268172
20WEE11.82968482
21MATK1.82578162
22MAP3K131.71961791
23CDC71.61900906
24EIF2AK11.59934085
25IRAK41.57795893
26ZAP701.57473968
27TSSK61.56489689
28ICK1.54309935
29VRK11.48590172
30PIM11.39370273
31RPS6KA41.38078893
32MAP3K111.37265470
33TAOK11.37147334
34TRIB31.36028004
35DDR21.30501036
36PLK41.28454488
37CDK41.26822769
38MAP3K11.25579349
39GRK11.23895052
40MAP3K101.23580804
41IRAK21.23353809
42JAK31.22957294
43TBK11.22774207
44MAP2K31.22699255
45TTK1.21553954
46GRK61.20363864
47MAP3K21.19088036
48STK31.18887687
49BTK1.12888228
50EIF2AK31.12028948
51PDPK11.11435183
52BRSK21.10340329
53CSF1R1.10111629
54IKBKE1.09368389
55NEK61.07631733
56CCNB11.07572994
57KIT1.06896815
58SIK31.06242242
59BLK1.04395103
60NME21.02624834
61RIPK11.02423231
62SYK1.01717773
63CHEK21.01374039
64DYRK31.01366220
65ACVR1B0.99708861
66MAPK110.96934936
67PLK10.96859380
68RIPK40.94910293
69MAPKAPK30.94432586
70IKBKB0.93176753
71STK40.93131196
72PDK10.91512916
73TEC0.90537837
74ERN10.90302012
75SIK10.89401656
76MOS0.89094522
77ADRBK20.89024263
78HCK0.87953102
79SCYL20.87479610
80CDK60.85509122
81KSR20.85329933
82JAK10.85261651
83CAMK1D0.85241810
84MAP3K80.84543923
85CDC42BPA0.84107600
86SIK20.83996368
87FES0.83823557
88JAK20.83377249
89RPS6KB20.82440996
90LYN0.81790132
91IRAK10.81309895
92CDK70.81015108
93LATS10.80476682
94MAP3K60.79585215
95GRK70.78862986
96RPS6KA20.78478435
97ATR0.78421563
98PKN20.78145369
99LCK0.77577214
100ALK0.77268733
101ITK0.76555691
102SRPK10.74186342
103TTN0.73679215
104AURKB0.73140625
105CHEK10.71365899
106PDGFRB0.68670826
107BRD40.68473880
108TYRO30.68423190
109MAPK70.67917715
110PIM20.67507310
111MAPK120.66299611
112ABL20.66235430
113MKNK20.65211030
114CAMK1G0.64280709
115BRSK10.63506460
116MAP3K50.63372150
117MAP3K140.62343717
118PLK30.62248799
119MAPK150.61875254
120MELK0.61282703
121CSK0.60880650
122TESK20.60677064
123CDK90.60531277
124RAF10.59220333
125PAK40.59149010
126PRKAA20.56952406
127CHUK0.56027684
128TLK10.55641563
129RPS6KL10.55354670
130RPS6KC10.55354670
131CAMKK20.55189117
132PRKAA10.54665152
133FGFR30.54392395
134YES10.54287486
135FGFR40.53434747
136CDK20.53237751
137STK240.52924414
138AKT30.52498555
139CLK10.52475987
140GSK3A0.50150287
141MAPK40.49793512
142CDK80.48600192
143NEK90.48473454
144PTK60.47931966
145PDGFRA0.45145094
146RPS6KA60.43249303
147CDK30.42270627
148SGK30.40493924
149EPHB10.37738525
150RPS6KA10.36406632
151KSR10.33975380
152RPS6KB10.33629386
153MAPKAPK20.33527466

Predicted pathways (KEGG)

RankGene SetZ-score
1Phototransduction_Homo sapiens_hsa047444.25667123
2Vitamin B6 metabolism_Homo sapiens_hsa007502.75713284
3DNA replication_Homo sapiens_hsa030302.60990319
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.23197576
5Rheumatoid arthritis_Homo sapiens_hsa053232.10899843
6Cell cycle_Homo sapiens_hsa041101.97813976
7Mismatch repair_Homo sapiens_hsa034301.82956575
8Malaria_Homo sapiens_hsa051441.79568019
9Primary immunodeficiency_Homo sapiens_hsa053401.79059748
10RNA transport_Homo sapiens_hsa030131.76641572
11Antigen processing and presentation_Homo sapiens_hsa046121.75815303
12B cell receptor signaling pathway_Homo sapiens_hsa046621.73428942
13Base excision repair_Homo sapiens_hsa034101.73068672
14RNA polymerase_Homo sapiens_hsa030201.72827807
15Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.72738486
16Staphylococcus aureus infection_Homo sapiens_hsa051501.72702052
17Other glycan degradation_Homo sapiens_hsa005111.69690214
18Graft-versus-host disease_Homo sapiens_hsa053321.63559758
19NF-kappa B signaling pathway_Homo sapiens_hsa040641.58686521
20Leishmaniasis_Homo sapiens_hsa051401.56991989
21Bladder cancer_Homo sapiens_hsa052191.56545036
22Glycosaminoglycan degradation_Homo sapiens_hsa005311.54749059
23Osteoclast differentiation_Homo sapiens_hsa043801.54659213
24Phagosome_Homo sapiens_hsa041451.52550439
25Folate biosynthesis_Homo sapiens_hsa007901.46586460
26Vitamin digestion and absorption_Homo sapiens_hsa049771.44787487
27Measles_Homo sapiens_hsa051621.42407401
28Caffeine metabolism_Homo sapiens_hsa002321.42395700
29Salmonella infection_Homo sapiens_hsa051321.42243288
30p53 signaling pathway_Homo sapiens_hsa041151.41969821
31Herpes simplex infection_Homo sapiens_hsa051681.38063301
32Intestinal immune network for IgA production_Homo sapiens_hsa046721.36126924
33Spliceosome_Homo sapiens_hsa030401.35201645
34Homologous recombination_Homo sapiens_hsa034401.33762182
35Hematopoietic cell lineage_Homo sapiens_hsa046401.32520444
36Fanconi anemia pathway_Homo sapiens_hsa034601.31983154
37One carbon pool by folate_Homo sapiens_hsa006701.29556769
38Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.24889759
39Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.24002270
40Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.22924303
41Lysosome_Homo sapiens_hsa041421.19346821
42Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.16927537
43AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.16254857
44Epstein-Barr virus infection_Homo sapiens_hsa051691.15785428
45Pyrimidine metabolism_Homo sapiens_hsa002401.14249235
46Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.14200274
47Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.13205936
48Nucleotide excision repair_Homo sapiens_hsa034201.13079974
49Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.13072490
50Autoimmune thyroid disease_Homo sapiens_hsa053201.08484517
51Cytokine-cytokine receptor interaction_Homo sapiens_hsa040601.07950046
52Toll-like receptor signaling pathway_Homo sapiens_hsa046201.06224320
53Pentose phosphate pathway_Homo sapiens_hsa000301.05430738
54mRNA surveillance pathway_Homo sapiens_hsa030151.04534280
55Chronic myeloid leukemia_Homo sapiens_hsa052201.04466685
56Apoptosis_Homo sapiens_hsa042101.04425536
57Type I diabetes mellitus_Homo sapiens_hsa049401.03972115
58Prolactin signaling pathway_Homo sapiens_hsa049171.02990641
59Influenza A_Homo sapiens_hsa051641.02741026
60VEGF signaling pathway_Homo sapiens_hsa043701.02693126
61Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.01122572
62Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.00801592
63Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.00277629
64Jak-STAT signaling pathway_Homo sapiens_hsa046300.99559797
65Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.99470566
66Cyanoamino acid metabolism_Homo sapiens_hsa004600.98819899
67Hepatitis B_Homo sapiens_hsa051610.98484297
68Viral myocarditis_Homo sapiens_hsa054160.98238475
69Asthma_Homo sapiens_hsa053100.98067009
70RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.96988844
71Collecting duct acid secretion_Homo sapiens_hsa049660.93166542
72Neurotrophin signaling pathway_Homo sapiens_hsa047220.93011567
73Drug metabolism - other enzymes_Homo sapiens_hsa009830.92896319
74Renal cell carcinoma_Homo sapiens_hsa052110.90673849
75RNA degradation_Homo sapiens_hsa030180.90320296
76Sphingolipid signaling pathway_Homo sapiens_hsa040710.90224189
77Basal transcription factors_Homo sapiens_hsa030220.90040878
78NOD-like receptor signaling pathway_Homo sapiens_hsa046210.89280046
79T cell receptor signaling pathway_Homo sapiens_hsa046600.88377695
80Endometrial cancer_Homo sapiens_hsa052130.87305593
81Tuberculosis_Homo sapiens_hsa051520.86929380
82Shigellosis_Homo sapiens_hsa051310.86734559
83Amoebiasis_Homo sapiens_hsa051460.86686871
84Legionellosis_Homo sapiens_hsa051340.86314300
85ABC transporters_Homo sapiens_hsa020100.85515385
86Complement and coagulation cascades_Homo sapiens_hsa046100.83817462
87Transcriptional misregulation in cancer_Homo sapiens_hsa052020.83415891
88African trypanosomiasis_Homo sapiens_hsa051430.83349439
89Viral carcinogenesis_Homo sapiens_hsa052030.82454209
90Glycerophospholipid metabolism_Homo sapiens_hsa005640.82438002
91Acute myeloid leukemia_Homo sapiens_hsa052210.82167394
92Adipocytokine signaling pathway_Homo sapiens_hsa049200.81781752
93Pancreatic cancer_Homo sapiens_hsa052120.77810627
94Toxoplasmosis_Homo sapiens_hsa051450.74245288
95Systemic lupus erythematosus_Homo sapiens_hsa053220.73906621
96Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.73732324
97Sphingolipid metabolism_Homo sapiens_hsa006000.73192179
98Purine metabolism_Homo sapiens_hsa002300.73056095
99Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.72298493
100Thyroid cancer_Homo sapiens_hsa052160.71342035
101Non-small cell lung cancer_Homo sapiens_hsa052230.71065618
102Regulation of autophagy_Homo sapiens_hsa041400.70918509
103Prostate cancer_Homo sapiens_hsa052150.70030860
104HTLV-I infection_Homo sapiens_hsa051660.69959981
105Notch signaling pathway_Homo sapiens_hsa043300.69127864
106Prion diseases_Homo sapiens_hsa050200.69014864
107Lysine degradation_Homo sapiens_hsa003100.68994904
108Fructose and mannose metabolism_Homo sapiens_hsa000510.65661123
109Chemokine signaling pathway_Homo sapiens_hsa040620.64378225
110FoxO signaling pathway_Homo sapiens_hsa040680.62196224
111HIF-1 signaling pathway_Homo sapiens_hsa040660.61339533
112Endocytosis_Homo sapiens_hsa041440.58253262
113Small cell lung cancer_Homo sapiens_hsa052220.58218156
114Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.58026816
115Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.58022190
116Phospholipase D signaling pathway_Homo sapiens_hsa040720.58008245
117mTOR signaling pathway_Homo sapiens_hsa041500.57959473
118Non-homologous end-joining_Homo sapiens_hsa034500.57698260
119Insulin resistance_Homo sapiens_hsa049310.57552640
120Pertussis_Homo sapiens_hsa051330.57372745
121Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.57128772
122GnRH signaling pathway_Homo sapiens_hsa049120.56348023
123Carbohydrate digestion and absorption_Homo sapiens_hsa049730.56120293
124Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.56055787
125Vibrio cholerae infection_Homo sapiens_hsa051100.55759903
126Central carbon metabolism in cancer_Homo sapiens_hsa052300.55514032
127Proteoglycans in cancer_Homo sapiens_hsa052050.54444278
128ErbB signaling pathway_Homo sapiens_hsa040120.54246492
129Glioma_Homo sapiens_hsa052140.53587693
130Circadian rhythm_Homo sapiens_hsa047100.52688411
131TNF signaling pathway_Homo sapiens_hsa046680.51621102
132Platelet activation_Homo sapiens_hsa046110.50453669
133Leukocyte transendothelial migration_Homo sapiens_hsa046700.49582188
134Inositol phosphate metabolism_Homo sapiens_hsa005620.48633331
135Fat digestion and absorption_Homo sapiens_hsa049750.48037495
136Dorso-ventral axis formation_Homo sapiens_hsa043200.47055744
137Colorectal cancer_Homo sapiens_hsa052100.45530441
138Hepatitis C_Homo sapiens_hsa051600.44830945
139Allograft rejection_Homo sapiens_hsa053300.44425659
140N-Glycan biosynthesis_Homo sapiens_hsa005100.43703239
141Biosynthesis of amino acids_Homo sapiens_hsa012300.42915607
142Estrogen signaling pathway_Homo sapiens_hsa049150.42491777
143MicroRNAs in cancer_Homo sapiens_hsa052060.41601871
144Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.41308721
145SNARE interactions in vesicular transport_Homo sapiens_hsa041300.40941591
146Longevity regulating pathway - mammal_Homo sapiens_hsa042110.40410875
147Choline metabolism in cancer_Homo sapiens_hsa052310.40243342
148Type II diabetes mellitus_Homo sapiens_hsa049300.38353555
149Insulin signaling pathway_Homo sapiens_hsa049100.38249523

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