Rank | Gene Set | Z-score |
---|---|---|
1 | drug transmembrane transport (GO:0006855) | 9.75583989 |
2 | lysine metabolic process (GO:0006553) | 8.58185812 |
3 | lysine catabolic process (GO:0006554) | 8.58185812 |
4 | * urate metabolic process (GO:0046415) | 8.45523118 |
5 | aminoglycoside antibiotic metabolic process (GO:0030647) | 8.36797422 |
6 | drug transport (GO:0015893) | 8.22186206 |
7 | epoxygenase P450 pathway (GO:0019373) | 7.90728528 |
8 | organic cation transport (GO:0015695) | 7.64961836 |
9 | regulation of fibrinolysis (GO:0051917) | 7.63213823 |
10 | omega-hydroxylase P450 pathway (GO:0097267) | 7.36049471 |
11 | complement activation, alternative pathway (GO:0006957) | 7.30725469 |
12 | negative regulation of fibrinolysis (GO:0051918) | 7.29826115 |
13 | regulation of protein activation cascade (GO:2000257) | 7.17388443 |
14 | cysteine metabolic process (GO:0006534) | 7.07700532 |
15 | glyoxylate metabolic process (GO:0046487) | 6.94843271 |
16 | regulation of complement activation (GO:0030449) | 6.74597792 |
17 | drug catabolic process (GO:0042737) | 6.42898129 |
18 | ethanol oxidation (GO:0006069) | 6.42291037 |
19 | cellular glucuronidation (GO:0052695) | 6.22289950 |
20 | protein carboxylation (GO:0018214) | 6.21418567 |
21 | peptidyl-glutamic acid carboxylation (GO:0017187) | 6.21418567 |
22 | quaternary ammonium group transport (GO:0015697) | 6.17671345 |
23 | exogenous drug catabolic process (GO:0042738) | 6.12141901 |
24 | response to mercury ion (GO:0046689) | 5.96494324 |
25 | urea metabolic process (GO:0019627) | 5.94999029 |
26 | uronic acid metabolic process (GO:0006063) | 5.92355284 |
27 | glucuronate metabolic process (GO:0019585) | 5.92355284 |
28 | fibrinolysis (GO:0042730) | 5.91221897 |
29 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 5.86421823 |
30 | L-phenylalanine catabolic process (GO:0006559) | 5.86421823 |
31 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 5.83982351 |
32 | L-phenylalanine metabolic process (GO:0006558) | 5.83982351 |
33 | aromatic amino acid family catabolic process (GO:0009074) | 5.79737528 |
34 | aspartate family amino acid catabolic process (GO:0009068) | 5.79344867 |
35 | blood coagulation, intrinsic pathway (GO:0007597) | 5.76616582 |
36 | * phosphate ion transport (GO:0006817) | 5.71660618 |
37 | indole-containing compound catabolic process (GO:0042436) | 5.62077674 |
38 | indolalkylamine catabolic process (GO:0046218) | 5.62077674 |
39 | tryptophan catabolic process (GO:0006569) | 5.62077674 |
40 | homocysteine metabolic process (GO:0050667) | 5.59628741 |
41 | negative regulation of cholesterol transport (GO:0032375) | 5.56344471 |
42 | negative regulation of sterol transport (GO:0032372) | 5.56344471 |
43 | short-chain fatty acid metabolic process (GO:0046459) | 5.54331896 |
44 | tricarboxylic acid metabolic process (GO:0072350) | 5.49434682 |
45 | excretion (GO:0007588) | 5.42177742 |
46 | nitrogen cycle metabolic process (GO:0071941) | 5.41166716 |
47 | fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) | 5.32895027 |
48 | nonribosomal peptide biosynthetic process (GO:0019184) | 5.32745392 |
49 | tryptophan metabolic process (GO:0006568) | 5.32443621 |
50 | oxidative demethylation (GO:0070989) | 5.29946781 |
51 | vitamin D metabolic process (GO:0042359) | 5.22035152 |
52 | ethanol metabolic process (GO:0006067) | 5.16556932 |
53 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 5.13559083 |
54 | valine metabolic process (GO:0006573) | 5.12651868 |
55 | branched-chain amino acid metabolic process (GO:0009081) | 5.12624683 |
56 | bile acid metabolic process (GO:0008206) | 5.08985120 |
57 | serine family amino acid catabolic process (GO:0009071) | 5.07034471 |
58 | urea cycle (GO:0000050) | 5.06446442 |
59 | 2-oxoglutarate metabolic process (GO:0006103) | 4.94531812 |
60 | amino-acid betaine metabolic process (GO:0006577) | 4.92035386 |
61 | regulation of plasminogen activation (GO:0010755) | 4.91046562 |
62 | renal absorption (GO:0070293) | 4.89095732 |
63 | serine family amino acid metabolic process (GO:0009069) | 4.88985675 |
64 | cellular modified amino acid catabolic process (GO:0042219) | 4.84783229 |
65 | glutathione biosynthetic process (GO:0006750) | 4.84021665 |
66 | phenylpropanoid metabolic process (GO:0009698) | 4.81788033 |
67 | metanephric tubule development (GO:0072170) | 4.80899815 |
68 | metanephric nephron tubule development (GO:0072234) | 4.80899815 |
69 | regulation of triglyceride catabolic process (GO:0010896) | 4.80195735 |
70 | toxin transport (GO:1901998) | 4.74608136 |
71 | kynurenine metabolic process (GO:0070189) | 4.73543850 |
72 | glycine metabolic process (GO:0006544) | 4.73428892 |
73 | negative regulation of blood coagulation (GO:0030195) | 4.67839351 |
74 | negative regulation of hemostasis (GO:1900047) | 4.67839351 |
75 | cellular ketone body metabolic process (GO:0046950) | 4.66685305 |
76 | amino-acid betaine transport (GO:0015838) | 4.65758499 |
77 | carnitine transport (GO:0015879) | 4.65758499 |
78 | protein activation cascade (GO:0072376) | 4.60503082 |
79 | fatty acid beta-oxidation (GO:0006635) | 4.57570517 |
80 | negative regulation of protein activation cascade (GO:2000258) | 4.57517288 |
81 | acetyl-CoA metabolic process (GO:0006084) | 4.53109719 |
82 | imidazole-containing compound metabolic process (GO:0052803) | 4.49702012 |
83 | bile acid and bile salt transport (GO:0015721) | 4.44303650 |
84 | glutamate metabolic process (GO:0006536) | 4.44004029 |
85 | metanephric nephron epithelium development (GO:0072243) | 4.41576131 |
86 | high-density lipoprotein particle remodeling (GO:0034375) | 4.40303014 |
87 | modified amino acid transport (GO:0072337) | 4.38118924 |
88 | triglyceride homeostasis (GO:0070328) | 4.37622959 |
89 | acylglycerol homeostasis (GO:0055090) | 4.37622959 |
90 | branched-chain amino acid catabolic process (GO:0009083) | 4.37606532 |
91 | protein-lipid complex remodeling (GO:0034368) | 4.35369727 |
92 | macromolecular complex remodeling (GO:0034367) | 4.35369727 |
93 | plasma lipoprotein particle remodeling (GO:0034369) | 4.35369727 |
94 | phospholipid efflux (GO:0033700) | 4.34552967 |
95 | regulation of cholesterol esterification (GO:0010872) | 4.33953311 |
96 | carnitine metabolic process (GO:0009437) | 4.33782824 |
97 | negative regulation of coagulation (GO:0050819) | 4.33514763 |
98 | fructose metabolic process (GO:0006000) | 4.31729490 |
99 | * phosphate ion transmembrane transport (GO:0035435) | 4.31250972 |
100 | fatty acid oxidation (GO:0019395) | 4.29855715 |
101 | aromatic amino acid family metabolic process (GO:0009072) | 4.26567472 |
102 | S-adenosylmethionine metabolic process (GO:0046500) | 4.24671435 |
103 | proline metabolic process (GO:0006560) | 4.22519125 |
104 | lipid oxidation (GO:0034440) | 4.21690784 |
105 | negative regulation of wound healing (GO:0061045) | 4.21331770 |
106 | trivalent inorganic anion homeostasis (GO:0072506) | 4.20006827 |
107 | phosphate ion homeostasis (GO:0055062) | 4.20006827 |
108 | regulation of humoral immune response (GO:0002920) | 4.19679940 |
109 | cholesterol efflux (GO:0033344) | 4.19328547 |
110 | response to phenylpropanoid (GO:0080184) | 4.18689381 |
111 | alpha-amino acid catabolic process (GO:1901606) | 4.18444400 |
112 | cellular amino acid catabolic process (GO:0009063) | 4.17941405 |
113 | complement activation (GO:0006956) | 4.17693444 |
114 | tyrosine metabolic process (GO:0006570) | 4.15147191 |
115 | complement activation, classical pathway (GO:0006958) | 4.13525946 |
116 | sulfur amino acid catabolic process (GO:0000098) | 4.13100688 |
117 | serine family amino acid biosynthetic process (GO:0009070) | 4.09296297 |
118 | metanephric epithelium development (GO:0072207) | 4.02842170 |
119 | ketone body metabolic process (GO:1902224) | 4.02356274 |
120 | reverse cholesterol transport (GO:0043691) | 4.00606178 |
121 | indolalkylamine metabolic process (GO:0006586) | 3.98247403 |
122 | flavonoid metabolic process (GO:0009812) | 3.98046619 |
123 | negative regulation of lipase activity (GO:0060192) | 3.95255084 |
124 | acute-phase response (GO:0006953) | 3.92878913 |
125 | fatty acid catabolic process (GO:0009062) | 3.88449967 |
126 | intestinal cholesterol absorption (GO:0030299) | 3.87547779 |
127 | peptide biosynthetic process (GO:0043043) | 3.83694597 |
128 | negative regulation of complement activation (GO:0045916) | 3.82904536 |
129 | benzene-containing compound metabolic process (GO:0042537) | 3.82275416 |
130 | positive regulation of lipoprotein lipase activity (GO:0051006) | 3.82087752 |
131 | positive regulation of triglyceride lipase activity (GO:0061365) | 3.82087752 |
132 | alkaloid metabolic process (GO:0009820) | 3.79746882 |
133 | organic acid catabolic process (GO:0016054) | 3.79276813 |
134 | carboxylic acid catabolic process (GO:0046395) | 3.79276813 |
135 | positive regulation of hemostasis (GO:1900048) | 3.77620955 |
136 | positive regulation of blood coagulation (GO:0030194) | 3.77620955 |
137 | indole-containing compound metabolic process (GO:0042430) | 3.76403621 |
138 | hormone catabolic process (GO:0042447) | 3.75585945 |
139 | glycoside metabolic process (GO:0016137) | 3.74009884 |
140 | positive regulation of heterotypic cell-cell adhesion (GO:0034116) | 3.73348618 |
141 | monocarboxylic acid catabolic process (GO:0072329) | 3.71948196 |
142 | nephron tubule development (GO:0072080) | 3.71207940 |
143 | amine catabolic process (GO:0009310) | 3.67029488 |
144 | cellular biogenic amine catabolic process (GO:0042402) | 3.67029488 |
145 | arginine metabolic process (GO:0006525) | 3.66543598 |
146 | bile acid biosynthetic process (GO:0006699) | 3.63476413 |
147 | response to growth hormone (GO:0060416) | 3.62570651 |
148 | glutathione derivative biosynthetic process (GO:1901687) | 3.58821851 |
149 | glutathione derivative metabolic process (GO:1901685) | 3.58821851 |
150 | drug metabolic process (GO:0017144) | 3.58619538 |
151 | glutathione metabolic process (GO:0006749) | 3.58421562 |
152 | daunorubicin metabolic process (GO:0044597) | 3.55674685 |
153 | polyketide metabolic process (GO:0030638) | 3.55674685 |
154 | doxorubicin metabolic process (GO:0044598) | 3.55674685 |
155 | plasma lipoprotein particle clearance (GO:0034381) | 3.53622293 |
156 | aldehyde catabolic process (GO:0046185) | 3.53471354 |
157 | very-low-density lipoprotein particle assembly (GO:0034379) | 3.52929837 |
158 | vitamin transport (GO:0051180) | 3.52032135 |
159 | dicarboxylic acid metabolic process (GO:0043648) | 3.51532348 |
160 | cytolysis (GO:0019835) | 3.51253822 |
161 | peptide catabolic process (GO:0043171) | 3.50830410 |
162 | xenobiotic metabolic process (GO:0006805) | 3.46845403 |
163 | positive regulation of coagulation (GO:0050820) | 3.46819694 |
164 | biotin metabolic process (GO:0006768) | 3.45127714 |
165 | opsonization (GO:0008228) | 3.44548854 |
166 | NADH metabolic process (GO:0006734) | 3.44115539 |
167 | xenobiotic catabolic process (GO:0042178) | 3.43812469 |
168 | polyol transport (GO:0015791) | 3.34715737 |
169 | small molecule catabolic process (GO:0044282) | 3.31429543 |
170 | renal tubule development (GO:0061326) | 3.28445244 |
171 | L-ascorbic acid metabolic process (GO:0019852) | 3.27886420 |
172 | sodium-independent organic anion transport (GO:0043252) | 3.27524756 |
173 | oxaloacetate metabolic process (GO:0006107) | 3.27346105 |
174 | dicarboxylic acid biosynthetic process (GO:0043650) | 3.26809746 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 8.06981749 |
2 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 6.54658910 |
3 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 5.54463575 |
4 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 4.93823688 |
5 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 4.72261240 |
6 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 3.56091496 |
7 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 3.01649291 |
8 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 2.99561026 |
9 | GATA1_22025678_ChIP-Seq_K562_Human | 2.94070931 |
10 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 2.88840212 |
11 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 2.85945320 |
12 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.79789769 |
13 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 2.37331476 |
14 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 2.24790184 |
15 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.18448460 |
16 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 2.15090168 |
17 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 2.13602293 |
18 | CLOCK_20551151_ChIP-Seq_293T_Human | 2.11729865 |
19 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 2.10781962 |
20 | TCF7L2_21901280_ChIP-Seq_H4IIE_Rat | 2.09428991 |
21 | AR_21909140_ChIP-Seq_LNCAP_Human | 2.02742312 |
22 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 2.01009474 |
23 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.81956714 |
24 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.81447674 |
25 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.80611405 |
26 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 1.77985288 |
27 | * HNF4A_19822575_ChIP-Seq_HepG2_Human | 1.65411986 |
28 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.59982112 |
29 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.59691805 |
30 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.57203131 |
31 | VDR_22108803_ChIP-Seq_LS180_Human | 1.56310974 |
32 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.55931563 |
33 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.51836602 |
34 | GATA4_25053715_ChIP-Seq_YYC3_Human | 1.49598907 |
35 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.47964065 |
36 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.46748945 |
37 | * SOX2_27498859_Chip-Seq_STOMACH_Mouse | 1.46034459 |
38 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.44436405 |
39 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.29858155 |
40 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.25059349 |
41 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.22778777 |
42 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.22145487 |
43 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.20938369 |
44 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.20680404 |
45 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.20650724 |
46 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.19919396 |
47 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.13138148 |
48 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.11740721 |
49 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.11221134 |
50 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.11058429 |
51 | GATA6_25053715_ChIP-Seq_YYC3_Human | 1.09668566 |
52 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.07055853 |
53 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.05366502 |
54 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.03891491 |
55 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 1.01509651 |
56 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.99508013 |
57 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.96795908 |
58 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.96046263 |
59 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.94688292 |
60 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 0.93580884 |
61 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 0.93580884 |
62 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 0.92450315 |
63 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 0.91440646 |
64 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.89651434 |
65 | SOX2_20726797_ChIP-Seq_SW620_Human | 0.87244064 |
66 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.86470620 |
67 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 0.85994682 |
68 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.85980922 |
69 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 0.83949974 |
70 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.83907501 |
71 | RXR_22108803_ChIP-Seq_LS180_Human | 0.83817696 |
72 | FOXA1_25552417_ChIP-Seq_VCAP_Human | 0.83473653 |
73 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.83304741 |
74 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 0.83101601 |
75 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.81627052 |
76 | MYC_19915707_ChIP-ChIP_AK7_Human | 0.80248574 |
77 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 0.78951126 |
78 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 0.78889813 |
79 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 0.78889813 |
80 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 0.78825660 |
81 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 0.78656591 |
82 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 0.77923184 |
83 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 0.77829541 |
84 | GATA3_20176728_ChIP-ChIP_TSCs_Mouse | 0.77750760 |
85 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.76428147 |
86 | FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.75204236 |
87 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.74818988 |
88 | SMAD2/3_21741376_ChIP-Seq_ESCs_Human | 0.74670770 |
89 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.74641378 |
90 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.74625697 |
91 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.74406850 |
92 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 0.74396323 |
93 | P63_20808887_ChIP-Seq_KERATINOCYTES_Human | 0.74102323 |
94 | TP53_16413492_ChIP-PET_HCT116_Human | 0.73897452 |
95 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 0.72997916 |
96 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.72835752 |
97 | CDX2_21074721_ChIP-Seq_CACO-2_Mouse | 0.72739549 |
98 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.72204405 |
99 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.71779493 |
100 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 0.71127047 |
101 | HNFA_21074721_ChIP-Seq_CACO-2_Human | 0.70614329 |
102 | GBX2_23144817_ChIP-Seq_PC3_Human | 0.67473582 |
103 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.67170723 |
104 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 0.67166985 |
105 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.66578510 |
106 | PHF8_20622853_ChIP-Seq_HELA_Human | 0.66280931 |
107 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 0.66151328 |
108 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.66028708 |
109 | TP63_23658742_ChIP-Seq_EP156T_Human | 0.65891856 |
110 | RAC3_21632823_ChIP-Seq_H3396_Human | 0.65346291 |
111 | GATA2_19941826_ChIP-Seq_K562_Human | 0.65270928 |
112 | NANOG_18692474_ChIP-Seq_MEFs_Mouse | 0.64927917 |
113 | NFYA_21822215_ChIP-Seq_K562_Human | 0.64673491 |
114 | SMAD1_18555785_Chip-Seq_ESCs_Mouse | 0.64433973 |
115 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 0.64150450 |
116 | P53_21459846_ChIP-Seq_SAOS-2_Human | 0.64024951 |
117 | AR_20517297_ChIP-Seq_VCAP_Human | 0.63415983 |
118 | ESRRB_18555785_Chip-Seq_ESCs_Mouse | 0.63177590 |
119 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.62381720 |
120 | CEBPB_22108803_ChIP-Seq_LS180_Human | 0.61878514 |
121 | RXRA_24833708_ChIP-Seq_LIVER_Mouse | 0.61474890 |
122 | SOX11_22085726_ChIP-Seq_ESNs_Mouse | 0.61447933 |
123 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 0.61411809 |
124 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.61293832 |
125 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 0.61275511 |
126 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 0.61214729 |
127 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.60510302 |
128 | CSB_26484114_Chip-Seq_FIBROBLAST_Human | 0.60351949 |
129 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.60337922 |
130 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.59953621 |
131 | ESET_19884257_ChIP-Seq_ESCs_Mouse | 0.59673417 |
132 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.59561209 |
133 | CBP_21632823_ChIP-Seq_H3396_Human | 0.59206434 |
134 | RUNX1_27457419_Chip-Seq_LIVER_Mouse | 0.58899467 |
135 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 0.58829635 |
136 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 0.58805713 |
137 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.58481590 |
138 | SMC4_20622854_ChIP-Seq_HELA_Human | 0.58364037 |
139 | STAT1_17558387_ChIP-Seq_HELA_Human | 0.58220817 |
140 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 0.58150929 |
141 | CREB1_26743006_Chip-Seq_LNCaP_Human | 0.56873647 |
142 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 0.56808145 |
143 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 0.56479385 |
144 | OCT4_20526341_ChIP-Seq_ESCs_Human | 0.56149785 |
145 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.55765507 |
146 | * SOX2_21211035_ChIP-Seq_LN229_Human | 0.55732302 |
147 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.55678566 |
148 | CJUN_26792858_Chip-Seq_BT549_Human | 0.55666708 |
149 | PU1_27457419_Chip-Seq_LIVER_Mouse | 0.54221871 |
150 | DROSHA_22980978_ChIP-Seq_HELA_Human | 0.53956020 |
151 | ZFX_18555785_Chip-Seq_ESCs_Mouse | 0.53557985 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0005360_urolithiasis | 8.23189603 |
2 | MP0002139_abnormal_hepatobiliary_system | 5.63960334 |
3 | MP0004043_abnormal_pH_regulation | 5.60243279 |
4 | MP0005332_abnormal_amino_acid | 4.82958073 |
5 | MP0004019_abnormal_vitamin_homeostasis | 4.74397540 |
6 | MP0003195_calcinosis | 4.42260614 |
7 | MP0002138_abnormal_hepatobiliary_system | 3.86423807 |
8 | MP0009643_abnormal_urine_homeostasis | 3.65915115 |
9 | MP0008875_abnormal_xenobiotic_pharmacok | 3.57598807 |
10 | MP0005365_abnormal_bile_salt | 3.40298510 |
11 | MP0001765_abnormal_ion_homeostasis | 3.29672690 |
12 | MP0005085_abnormal_gallbladder_physiolo | 3.24352792 |
13 | MP0003252_abnormal_bile_duct | 3.04725287 |
14 | MP0005636_abnormal_mineral_homeostasis | 2.88968044 |
15 | MP0001756_abnormal_urination | 2.88400733 |
16 | MP0002136_abnormal_kidney_physiology | 2.64647967 |
17 | MP0009697_abnormal_copulation | 2.45866968 |
18 | MP0003878_abnormal_ear_physiology | 2.34984195 |
19 | MP0005377_hearing/vestibular/ear_phenot | 2.34984195 |
20 | MP0001958_emphysema | 2.12652953 |
21 | MP0003806_abnormal_nucleotide_metabolis | 2.04493387 |
22 | MP0003186_abnormal_redox_activity | 1.75021915 |
23 | MP0005058_abnormal_lysosome_morphology | 1.71729261 |
24 | MP0005584_abnormal_enzyme/coenzyme_acti | 1.71326569 |
25 | MP0008961_abnormal_basal_metabolism | 1.62724454 |
26 | MP0005319_abnormal_enzyme/_coenzyme | 1.52526342 |
27 | MP0005451_abnormal_body_composition | 1.50095209 |
28 | MP0000538_abnormal_urinary_bladder | 1.49227959 |
29 | MP0001666_abnormal_nutrient_absorption | 1.42008860 |
30 | MP0005084_abnormal_gallbladder_morpholo | 1.37598845 |
31 | MP0003191_abnormal_cellular_cholesterol | 1.35158096 |
32 | MP0004885_abnormal_endolymph | 1.34723475 |
33 | MP0010329_abnormal_lipoprotein_level | 1.34237174 |
34 | MP0002876_abnormal_thyroid_physiology | 1.32309076 |
35 | MP0003300_gastrointestinal_ulcer | 1.31528961 |
36 | MP0002928_abnormal_bile_duct | 1.29558145 |
37 | MP0010368_abnormal_lymphatic_system | 1.29229002 |
38 | MP0001764_abnormal_homeostasis | 1.25600978 |
39 | MP0006036_abnormal_mitochondrial_physio | 1.23171219 |
40 | MP0002118_abnormal_lipid_homeostasis | 1.20196766 |
41 | MP0002168_other_aberrant_phenotype | 1.17262881 |
42 | MP0000230_abnormal_systemic_arterial | 1.11474324 |
43 | MP0005670_abnormal_white_adipose | 1.04957052 |
44 | MP0009053_abnormal_anal_canal | 1.04278669 |
45 | MP0005535_abnormal_body_temperature | 1.04183265 |
46 | MP0002135_abnormal_kidney_morphology | 0.99739151 |
47 | MP0000609_abnormal_liver_physiology | 0.99499073 |
48 | MP0008872_abnormal_physiological_respon | 0.95974983 |
49 | MP0002132_abnormal_respiratory_system | 0.89098800 |
50 | MP0001661_extended_life_span | 0.88097079 |
51 | MP0001915_intracranial_hemorrhage | 0.88016973 |
52 | MP0004147_increased_porphyrin_level | 0.87687730 |
53 | MP0005666_abnormal_adipose_tissue | 0.85128538 |
54 | MP0003638_abnormal_response/metabolism_ | 0.82454235 |
55 | MP0004264_abnormal_extraembryonic_tissu | 0.81825329 |
56 | MP0009642_abnormal_blood_homeostasis | 0.81574860 |
57 | MP0002896_abnormal_bone_mineralization | 0.80973624 |
58 | MP0009764_decreased_sensitivity_to | 0.80474625 |
59 | MP0005083_abnormal_biliary_tract | 0.78678076 |
60 | MP0005220_abnormal_exocrine_pancreas | 0.78669786 |
61 | MP0010234_abnormal_vibrissa_follicle | 0.77296141 |
62 | MP0003283_abnormal_digestive_organ | 0.70797644 |
63 | MP0005395_other_phenotype | 0.69283486 |
64 | MP0000598_abnormal_liver_morphology | 0.67777203 |
65 | MP0002089_abnormal_postnatal_growth/wei | 0.67629607 |
66 | MP0003172_abnormal_lysosome_physiology | 0.64237769 |
67 | MP0009763_increased_sensitivity_to | 0.64103336 |
68 | MP0003011_delayed_dark_adaptation | 0.63970991 |
69 | MP0008469_abnormal_protein_level | 0.63346477 |
70 | MP0002796_impaired_skin_barrier | 0.62180289 |
71 | MP0003656_abnormal_erythrocyte_physiolo | 0.62040981 |
72 | MP0003959_abnormal_lean_body | 0.61825046 |
73 | MP0003646_muscle_fatigue | 0.60769881 |
74 | MP0005464_abnormal_platelet_physiology | 0.57060296 |
75 | MP0002078_abnormal_glucose_homeostasis | 0.55578048 |
76 | MP0005408_hypopigmentation | 0.55203482 |
77 | MP0006035_abnormal_mitochondrial_morpho | 0.54318777 |
78 | MP0003329_amyloid_beta_deposits | 0.52401522 |
79 | MP0002909_abnormal_adrenal_gland | 0.51008836 |
80 | MP0004782_abnormal_surfactant_physiolog | 0.50671600 |
81 | MP0005187_abnormal_penis_morphology | 0.49116912 |
82 | MP0000747_muscle_weakness | 0.48936300 |
83 | MP0003690_abnormal_glial_cell | 0.45876046 |
84 | MP0000371_diluted_coat_color | 0.45869257 |
85 | MP0009840_abnormal_foam_cell | 0.45326031 |
86 | MP0003953_abnormal_hormone_level | 0.44452566 |
87 | MP0005334_abnormal_fat_pad | 0.42953915 |
88 | MP0005266_abnormal_metabolism | 0.41630117 |
89 | MP0005165_increased_susceptibility_to | 0.41446489 |
90 | MP0002282_abnormal_trachea_morphology | 0.40886409 |
91 | MP0008874_decreased_physiological_sensi | 0.40851378 |
92 | MP0005501_abnormal_skin_physiology | 0.40068374 |
93 | MP0001944_abnormal_pancreas_morphology | 0.38622550 |
94 | MP0002069_abnormal_eating/drinking_beha | 0.37561250 |
95 | MP0005376_homeostasis/metabolism_phenot | 0.37461509 |
96 | MP0002115_abnormal_skeleton_extremities | 0.36746513 |
97 | MP0000604_amyloidosis | 0.36661089 |
98 | MP0003795_abnormal_bone_structure | 0.34891900 |
99 | MP0009765_abnormal_xenobiotic_induced | 0.34594198 |
100 | MP0003879_abnormal_hair_cell | 0.33677781 |
101 | MP0000566_synostosis | 0.33649992 |
102 | MP0002971_abnormal_brown_adipose | 0.33537662 |
103 | MP0003868_abnormal_feces_composition | 0.33520968 |
104 | MP0000249_abnormal_blood_vessel | 0.33147223 |
105 | MP0009672_abnormal_birth_weight | 0.32659166 |
106 | MP0009785_altered_susceptibility_to | 0.32600735 |
107 | MP0005023_abnormal_wound_healing | 0.32491212 |
108 | MP0002332_abnormal_exercise_endurance | 0.32345260 |
109 | MP0005167_abnormal_blood-brain_barrier | 0.32303296 |
110 | MP0002249_abnormal_larynx_morphology | 0.31592381 |
111 | MP0005448_abnormal_energy_balance | 0.31475025 |
112 | MP0005375_adipose_tissue_phenotype | 0.31457886 |
113 | MP0003941_abnormal_skin_development | 0.31293161 |
114 | MP0005164_abnormal_response_to | 0.31202406 |
115 | MP0002998_abnormal_bone_remodeling | 0.30886030 |
116 | MP0001485_abnormal_pinna_reflex | 0.30781459 |
117 | MP0002098_abnormal_vibrissa_morphology | 0.30291450 |
118 | MP0003724_increased_susceptibility_to | 0.30113605 |
119 | MP0003221_abnormal_cardiomyocyte_apopto | 0.30084813 |
120 | MP0004130_abnormal_muscle_cell | 0.30072987 |
121 | MP0010386_abnormal_urinary_bladder | 0.29539483 |
122 | MP0003705_abnormal_hypodermis_morpholog | 0.29216225 |
123 | MP0005166_decreased_susceptibility_to | 0.28818029 |
124 | MP0002090_abnormal_vision | 0.28696014 |
125 | MP0003075_altered_response_to | 0.26770848 |
126 | MP0004272_abnormal_basement_membrane | 0.26491463 |
127 | MP0001545_abnormal_hematopoietic_system | 0.26357983 |
128 | MP0005397_hematopoietic_system_phenotyp | 0.26357983 |
129 | MP0000467_abnormal_esophagus_morphology | 0.25738782 |
130 | MP0001845_abnormal_inflammatory_respons | 0.25639056 |
131 | MP0000920_abnormal_myelination | 0.25563029 |
132 | MP0001663_abnormal_digestive_system | 0.25324203 |
133 | MP0003183_abnormal_peptide_metabolism | 0.24942363 |
134 | MP0004742_abnormal_vestibular_system | 0.24927145 |
135 | MP0000163_abnormal_cartilage_morphology | 0.24837171 |
136 | MP0005197_abnormal_uvea_morphology | 0.24729866 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Deep venous thrombosis (HP:0002625) | 9.20650243 |
2 | Prolonged partial thromboplastin time (HP:0003645) | 8.16402923 |
3 | Complement deficiency (HP:0004431) | 7.96185826 |
4 | Increased circulating renin level (HP:0000848) | 7.49213889 |
5 | Hypokalemic alkalosis (HP:0001949) | 7.05298020 |
6 | Hypobetalipoproteinemia (HP:0003563) | 6.97465673 |
7 | Metabolic alkalosis (HP:0200114) | 6.95864763 |
8 | Gout (HP:0001997) | 6.85203945 |
9 | Hypomagnesemia (HP:0002917) | 6.72626005 |
10 | Hyperactive renin-angiotensin system (HP:0000841) | 6.58888830 |
11 | Abnormality of complement system (HP:0005339) | 6.27423986 |
12 | Polyuria (HP:0000103) | 6.23454098 |
13 | Abnormality of chloride homeostasis (HP:0011422) | 5.92379323 |
14 | Abnormal urine output (HP:0012590) | 5.91943667 |
15 | Conjugated hyperbilirubinemia (HP:0002908) | 5.69034174 |
16 | Abnormality of magnesium homeostasis (HP:0004921) | 5.67746054 |
17 | Joint hemorrhage (HP:0005261) | 5.62733357 |
18 | Abnormality of renal excretion (HP:0011036) | 5.57310556 |
19 | Proximal tubulopathy (HP:0000114) | 5.25931840 |
20 | Systemic lupus erythematosus (HP:0002725) | 5.19761238 |
21 | Hyperuricemia (HP:0002149) | 5.05447017 |
22 | Increased purine levels (HP:0004368) | 5.05447017 |
23 | Polydipsia (HP:0001959) | 5.00394269 |
24 | Abnormal drinking behavior (HP:0030082) | 5.00394269 |
25 | Hyperglycinuria (HP:0003108) | 4.94615528 |
26 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 4.92947047 |
27 | Alkalosis (HP:0001948) | 4.80451444 |
28 | Tetany (HP:0001281) | 4.80397770 |
29 | Abnormality of the common coagulation pathway (HP:0010990) | 4.79111724 |
30 | Glomerulonephritis (HP:0000099) | 4.72681868 |
31 | Hyperlipoproteinemia (HP:0010980) | 4.67617387 |
32 | Abnormality of purine metabolism (HP:0004352) | 4.56715304 |
33 | Renal salt wasting (HP:0000127) | 4.55534620 |
34 | Abnormality of renin-angiotensin system (HP:0000847) | 4.54773243 |
35 | Hyperaldosteronism (HP:0000859) | 4.46678508 |
36 | Hypolipoproteinemia (HP:0010981) | 4.29518742 |
37 | Abnormality of glycine metabolism (HP:0010895) | 4.19845126 |
38 | Abnormality of serine family amino acid metabolism (HP:0010894) | 4.19845126 |
39 | Spontaneous abortion (HP:0005268) | 4.18786220 |
40 | Ketoacidosis (HP:0001993) | 4.02882987 |
41 | Abnormality of pyrimidine metabolism (HP:0004353) | 3.92214100 |
42 | Generalized aminoaciduria (HP:0002909) | 3.90407969 |
43 | Hypercalciuria (HP:0002150) | 3.69000177 |
44 | Ketosis (HP:0001946) | 3.68874343 |
45 | Abnormality of the level of lipoprotein cholesterol (HP:0010979) | 3.63129496 |
46 | Recurrent gram-negative bacterial infections (HP:0005420) | 3.58579562 |
47 | Nephritis (HP:0000123) | 3.56410664 |
48 | Renal tubular acidosis (HP:0001947) | 3.52093867 |
49 | Abnormality of urine glucose concentration (HP:0011016) | 3.51685835 |
50 | Glycosuria (HP:0003076) | 3.51685835 |
51 | Abnormality of nucleobase metabolism (HP:0010932) | 3.49370497 |
52 | Hypokalemia (HP:0002900) | 3.46860554 |
53 | Abnormality of the intrinsic pathway (HP:0010989) | 3.43039935 |
54 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 3.31255312 |
55 | Abnormality of fatty-acid metabolism (HP:0004359) | 3.25209321 |
56 | Fat malabsorption (HP:0002630) | 3.21714397 |
57 | Hyperglycinemia (HP:0002154) | 3.17598157 |
58 | Hypoalphalipoproteinemia (HP:0003233) | 3.10752193 |
59 | Hyperphosphaturia (HP:0003109) | 3.05805645 |
60 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 3.04351768 |
61 | Osteomalacia (HP:0002749) | 2.96116551 |
62 | Abnormality of proline metabolism (HP:0010907) | 2.94228067 |
63 | Hydroxyprolinuria (HP:0003080) | 2.94228067 |
64 | Delayed CNS myelination (HP:0002188) | 2.93235060 |
65 | Abnormality of potassium homeostasis (HP:0011042) | 2.90301675 |
66 | Hyperammonemia (HP:0001987) | 2.89331813 |
67 | Gingival bleeding (HP:0000225) | 2.86267524 |
68 | Abnormality of methionine metabolism (HP:0010901) | 2.85104924 |
69 | Abnormal urine phosphate concentration (HP:0012599) | 2.84782033 |
70 | Hypercholesterolemia (HP:0003124) | 2.84564957 |
71 | Nephrocalcinosis (HP:0000121) | 2.82800079 |
72 | Nephrolithiasis (HP:0000787) | 2.78740934 |
73 | Vascular calcification (HP:0004934) | 2.76851973 |
74 | Mitral stenosis (HP:0001718) | 2.70487091 |
75 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 2.67271478 |
76 | Delayed epiphyseal ossification (HP:0002663) | 2.65325593 |
77 | Hemorrhage of the eye (HP:0011885) | 2.57538869 |
78 | Metabolic acidosis (HP:0001942) | 2.55483201 |
79 | Rickets (HP:0002748) | 2.55407423 |
80 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.53649343 |
81 | Dicarboxylic aciduria (HP:0003215) | 2.53649343 |
82 | Hypophosphatemia (HP:0002148) | 2.51853950 |
83 | Epidermoid cyst (HP:0200040) | 2.48059529 |
84 | Enlarged kidneys (HP:0000105) | 2.46477907 |
85 | Cardiovascular calcification (HP:0011915) | 2.46432728 |
86 | Menorrhagia (HP:0000132) | 2.44527009 |
87 | Dehydration (HP:0001944) | 2.43059741 |
88 | Hyperbilirubinemia (HP:0002904) | 2.42985609 |
89 | Fair hair (HP:0002286) | 2.42774769 |
90 | Vomiting (HP:0002013) | 2.42474205 |
91 | Steatorrhea (HP:0002570) | 2.34612673 |
92 | Thrombophlebitis (HP:0004418) | 2.33779318 |
93 | Vacuolated lymphocytes (HP:0001922) | 2.30869978 |
94 | Malnutrition (HP:0004395) | 2.30465316 |
95 | Widely patent fontanelles and sutures (HP:0004492) | 2.29015890 |
96 | Lethargy (HP:0001254) | 2.25303498 |
97 | Confusion (HP:0001289) | 2.24368112 |
98 | Xanthomatosis (HP:0000991) | 2.23433782 |
99 | Purpura (HP:0000979) | 2.21929658 |
100 | Abnormality of sodium homeostasis (HP:0010931) | 2.21060642 |
101 | Hyponatremia (HP:0002902) | 2.19064439 |
102 | Metaphyseal cupping (HP:0003021) | 2.17148851 |
103 | Renal tubular dysfunction (HP:0000124) | 2.16753850 |
104 | Abnormal enzyme/coenzyme activity (HP:0012379) | 2.15372528 |
105 | Neonatal hypoglycemia (HP:0001998) | 2.10776339 |
106 | Potter facies (HP:0002009) | 2.09890119 |
107 | Facial shape deformation (HP:0011334) | 2.09890119 |
108 | Intrahepatic cholestasis (HP:0001406) | 2.09218290 |
109 | Abnormality of renal resorption (HP:0011038) | 2.08744720 |
110 | Arthropathy (HP:0003040) | 2.06820639 |
111 | Reduced antithrombin III activity (HP:0001976) | 2.06072419 |
112 | Abnormality of alkaline phosphatase activity (HP:0004379) | 2.05612537 |
113 | Abnormality of vitamin metabolism (HP:0100508) | 2.01915643 |
114 | Focal segmental glomerulosclerosis (HP:0000097) | 2.01630289 |
115 | Abnormality of serum amino acid levels (HP:0003112) | 2.01311763 |
116 | Chondrocalcinosis (HP:0000934) | 2.01067157 |
117 | Tubulointerstitial fibrosis (HP:0005576) | 1.99675819 |
118 | Methylmalonic aciduria (HP:0012120) | 1.99203300 |
119 | Adrenal overactivity (HP:0002717) | 1.99146040 |
120 | Pulmonary embolism (HP:0002204) | 1.93179984 |
121 | Bilateral sensorineural hearing impairment (HP:0008619) | 1.91405453 |
122 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 1.90714066 |
123 | Irritability (HP:0000737) | 1.89986708 |
124 | Abnormal tarsal ossification (HP:0008369) | 1.88819352 |
125 | Hypoglycemic coma (HP:0001325) | 1.88544575 |
126 | Abnormality of Sharpey fibers (HP:0100685) | 1.87926703 |
127 | Tubular atrophy (HP:0000092) | 1.87001037 |
128 | Nausea (HP:0002018) | 1.86945368 |
129 | Abnormality of the Achilles tendon (HP:0005109) | 1.85621300 |
130 | Impaired platelet aggregation (HP:0003540) | 1.84081221 |
131 | Abnormal platelet function (HP:0011869) | 1.84081221 |
132 | Neonatal onset (HP:0003623) | 1.83214827 |
133 | Thin bony cortex (HP:0002753) | 1.79695969 |
134 | Sensorimotor neuropathy (HP:0007141) | 1.78561911 |
135 | Glomerulosclerosis (HP:0000096) | 1.75044882 |
136 | Lymphangioma (HP:0100764) | 1.74651659 |
137 | Spastic diplegia (HP:0001264) | 1.70404745 |
138 | Elevated alkaline phosphatase (HP:0003155) | 1.69823047 |
139 | Hepatocellular carcinoma (HP:0001402) | 1.68226220 |
140 | Late onset (HP:0003584) | 1.66540721 |
141 | Hypotension (HP:0002615) | 1.65887664 |
142 | Hypophosphatemic rickets (HP:0004912) | 1.65169399 |
Rank | Gene Set | Z-score |
---|---|---|
1 | WNK3 | 8.51077124 |
2 | WNK4 | 8.47722929 |
3 | OXSR1 | 7.54826784 |
4 | STK39 | 4.25135755 |
5 | BCKDK | 3.34624706 |
6 | STK38L | 2.36979606 |
7 | PIK3CA | 2.21822305 |
8 | PDK4 | 1.91264970 |
9 | PDK3 | 1.91264970 |
10 | SGK494 | 1.83051651 |
11 | SGK223 | 1.83051651 |
12 | NEK1 | 1.82252138 |
13 | WNK1 | 1.72485047 |
14 | FGFR3 | 1.66761141 |
15 | NTRK3 | 1.45687039 |
16 | FGFR2 | 1.43344758 |
17 | MST1R | 1.40902404 |
18 | PDK2 | 1.39934859 |
19 | FGFR4 | 1.26631628 |
20 | STK38 | 1.21131370 |
21 | PDGFRA | 1.13404911 |
22 | SGK3 | 1.09205373 |
23 | SGK2 | 1.07717954 |
24 | MST4 | 0.98366813 |
25 | PINK1 | 0.90812190 |
26 | LRRK2 | 0.90399465 |
27 | ICK | 0.86042465 |
28 | ERN1 | 0.81902457 |
29 | GRK6 | 0.78185303 |
30 | EPHA2 | 0.76763096 |
31 | GSK3A | 0.74818871 |
32 | EPHB1 | 0.74210386 |
33 | MAP3K7 | 0.73169150 |
34 | INSRR | 0.67247293 |
35 | TIE1 | 0.61507817 |
36 | MAP3K3 | 0.61389716 |
37 | TRPM7 | 0.61340708 |
38 | CSF1R | 0.59750781 |
39 | ABL2 | 0.59108579 |
40 | DDR2 | 0.58573176 |
41 | MAPK11 | 0.58007584 |
42 | PTK2 | 0.56704159 |
43 | ADRBK2 | 0.56305026 |
44 | PRKAA1 | 0.55908049 |
45 | SGK1 | 0.54945379 |
46 | JAK1 | 0.53960851 |
47 | PTK6 | 0.53917553 |
48 | CDK12 | 0.53677101 |
49 | TGFBR2 | 0.52155563 |
50 | DYRK1B | 0.51938150 |
51 | PRKACB | 0.49605674 |
52 | PRKG1 | 0.49533199 |
53 | FRK | 0.48000794 |
54 | PRKAA2 | 0.46774464 |
55 | PRKCB | 0.46548173 |
56 | TNK2 | 0.45945974 |
57 | ERBB4 | 0.45780098 |
58 | PDPK1 | 0.44741632 |
59 | TRIB3 | 0.44023227 |
60 | FGFR1 | 0.43630039 |
61 | MET | 0.43103370 |
62 | CSNK1A1 | 0.42175664 |
63 | PRKCE | 0.38190053 |
64 | GRK1 | 0.37629411 |
65 | LATS1 | 0.37426562 |
66 | SIK1 | 0.37124907 |
67 | PRKCZ | 0.36983758 |
68 | PAK4 | 0.36339195 |
69 | CSNK1E | 0.34807596 |
70 | MAP3K14 | 0.34775704 |
71 | CDC42BPA | 0.34519335 |
72 | PDGFRB | 0.34089035 |
73 | ZAP70 | 0.33715016 |
74 | PAK3 | 0.33610592 |
75 | FER | 0.31849561 |
76 | TAOK3 | 0.31597250 |
77 | RIPK1 | 0.30942027 |
78 | CSNK1D | 0.29977373 |
79 | PDK1 | 0.29700017 |
80 | PRKG2 | 0.29496720 |
81 | TBK1 | 0.28792828 |
82 | MAPK10 | 0.27194458 |
83 | PRKCI | 0.26689972 |
84 | CAMKK2 | 0.26054741 |
85 | MAP2K4 | 0.25327939 |
86 | STK10 | 0.25039599 |
87 | PRKACG | 0.25012092 |
88 | JAK2 | 0.24819669 |
89 | TXK | 0.24812678 |
90 | STK11 | 0.24751263 |
91 | CDK6 | 0.24541069 |
92 | RET | 0.23970363 |
93 | CSNK2A2 | 0.23900957 |
94 | MAP3K2 | 0.22230883 |
95 | PTK2B | 0.21581372 |
96 | PRKCD | 0.21373542 |
97 | MAPK15 | 0.21175137 |
98 | CSNK2A1 | 0.20513287 |
99 | ACVR1B | 0.20419477 |
100 | MYLK | 0.20133123 |
101 | PRKD2 | 0.20131853 |
102 | NEK9 | 0.18537326 |
103 | IRAK2 | 0.17768013 |
104 | NTRK1 | 0.17736600 |
105 | MAP2K3 | 0.17220256 |
106 | MAPK7 | 0.17088558 |
107 | PRKCH | 0.15645938 |
108 | BMX | 0.15326716 |
109 | AKT2 | 0.15172771 |
110 | PRKCA | 0.14916561 |
111 | NME2 | 0.14198168 |
112 | EPHA4 | 0.12255400 |
113 | MAPK12 | 0.12227214 |
114 | MAP3K11 | 0.11834276 |
115 | PRKACA | 0.11235098 |
116 | DAPK2 | 0.10838373 |
117 | PIK3CG | 0.09849094 |
118 | PIM1 | 0.09810736 |
119 | PKN2 | 0.08521273 |
120 | CSK | 0.07192810 |
121 | MAPK4 | 0.06994494 |
122 | PRKCQ | 0.06633126 |
123 | KDR | 0.05759622 |
124 | ERBB2 | 0.05489296 |
125 | IGF1R | 0.05448583 |
126 | IRAK3 | 0.05271995 |
127 | MINK1 | 0.05106756 |
128 | INSR | 0.04770532 |
129 | TYK2 | 0.04658928 |
130 | MTOR | 0.04602801 |
131 | PRKCG | 0.04553461 |
132 | IRAK1 | 0.04052589 |
133 | SCYL2 | 0.02816188 |
134 | SRC | 0.02214592 |
135 | ROCK1 | 0.02156958 |
136 | CAMK4 | 0.01253631 |
137 | RPS6KA3 | 0.00803495 |
138 | MAP2K6 | 0.00517794 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Butanoate metabolism_Homo sapiens_hsa00650 | 3.61341503 |
2 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 3.36967260 |
3 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 3.25929877 |
4 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 3.24802170 |
5 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 3.20829151 |
6 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 3.18800435 |
7 | Propanoate metabolism_Homo sapiens_hsa00640 | 3.07470333 |
8 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 2.99967170 |
9 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 2.73607722 |
10 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 2.70930981 |
11 | Peroxisome_Homo sapiens_hsa04146 | 2.56102788 |
12 | Fatty acid degradation_Homo sapiens_hsa00071 | 2.53538927 |
13 | Tryptophan metabolism_Homo sapiens_hsa00380 | 2.49619743 |
14 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 2.37127438 |
15 | Pyruvate metabolism_Homo sapiens_hsa00620 | 2.28015102 |
16 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 2.21037744 |
17 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 2.15798686 |
18 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.99225213 |
19 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.98976397 |
20 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 1.95363055 |
21 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.92532729 |
22 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.87877071 |
23 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.84879002 |
24 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.78510118 |
25 | Bile secretion_Homo sapiens_hsa04976 | 1.76140926 |
26 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.71442079 |
27 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.68415705 |
28 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.65973169 |
29 | Carbon metabolism_Homo sapiens_hsa01200 | 1.65378668 |
30 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.54124058 |
31 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.50001408 |
32 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.47313715 |
33 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 1.35035083 |
34 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.34513902 |
35 | Lysine degradation_Homo sapiens_hsa00310 | 1.30944657 |
36 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.27844363 |
37 | Histidine metabolism_Homo sapiens_hsa00340 | 1.23694708 |
38 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.20478962 |
39 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.19579505 |
40 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.18419057 |
41 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.13892607 |
42 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.11668200 |
43 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.11655886 |
44 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.11353143 |
45 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.08602764 |
46 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.00363060 |
47 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.97285663 |
48 | Other glycan degradation_Homo sapiens_hsa00511 | 0.97203135 |
49 | Mineral absorption_Homo sapiens_hsa04978 | 0.95137699 |
50 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.95033162 |
51 | Prion diseases_Homo sapiens_hsa05020 | 0.91877095 |
52 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.91765361 |
53 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.90045602 |
54 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.89794689 |
55 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.87858223 |
56 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.85351673 |
57 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.84928086 |
58 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.77974671 |
59 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.75229672 |
60 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.74237004 |
61 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.69523254 |
62 | Retinol metabolism_Homo sapiens_hsa00830 | 0.66941984 |
63 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.63483146 |
64 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.62331845 |
65 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.56503198 |
66 | Metabolic pathways_Homo sapiens_hsa01100 | 0.54705660 |
67 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.51893236 |
68 | ABC transporters_Homo sapiens_hsa02010 | 0.49712942 |
69 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.49430419 |
70 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.47746257 |
71 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.46965474 |
72 | Lysosome_Homo sapiens_hsa04142 | 0.45034253 |
73 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.41749926 |
74 | Sulfur relay system_Homo sapiens_hsa04122 | 0.39923294 |
75 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.38314226 |
76 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.38215516 |
77 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.33605998 |
78 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.27663258 |
79 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.22301947 |
80 | Pertussis_Homo sapiens_hsa05133 | 0.20526130 |
81 | Parkinsons disease_Homo sapiens_hsa05012 | 0.20476713 |
82 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.16922421 |
83 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.16243996 |
84 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.15382279 |
85 | Insulin resistance_Homo sapiens_hsa04931 | 0.12251009 |
86 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.12092214 |
87 | Galactose metabolism_Homo sapiens_hsa00052 | 0.11470846 |
88 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.11052128 |
89 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.10761808 |
90 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.10217754 |
91 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.10207576 |
92 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.09700542 |
93 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.06480264 |
94 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.04969039 |
95 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.04052629 |
96 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.04027140 |
97 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.03511954 |
98 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.02909155 |
99 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.02501565 |
100 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.00852796 |
101 | Insulin signaling pathway_Homo sapiens_hsa04910 | -0.1881134 |
102 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | -0.1829714 |
103 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | -0.1724401 |
104 | ECM-receptor interaction_Homo sapiens_hsa04512 | -0.1400887 |
105 | Circadian rhythm_Homo sapiens_hsa04710 | -0.1357827 |
106 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | -0.1283463 |
107 | Serotonergic synapse_Homo sapiens_hsa04726 | -0.0831685 |
108 | Amoebiasis_Homo sapiens_hsa05146 | -0.0626185 |
109 | Ether lipid metabolism_Homo sapiens_hsa00565 | -0.0559823 |
110 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | -0.0488159 |
111 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | -0.0444505 |
112 | Cardiac muscle contraction_Homo sapiens_hsa04260 | -0.0443221 |
113 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | -0.0408711 |
114 | Alzheimers disease_Homo sapiens_hsa05010 | -0.0214812 |
115 | Sphingolipid metabolism_Homo sapiens_hsa00600 | -0.0151355 |
116 | Glucagon signaling pathway_Homo sapiens_hsa04922 | -0.0125774 |
117 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | -0.0117152 |
118 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | -0.0077016 |