SLC17A1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1drug transmembrane transport (GO:0006855)9.75583989
2lysine metabolic process (GO:0006553)8.58185812
3lysine catabolic process (GO:0006554)8.58185812
4* urate metabolic process (GO:0046415)8.45523118
5aminoglycoside antibiotic metabolic process (GO:0030647)8.36797422
6drug transport (GO:0015893)8.22186206
7epoxygenase P450 pathway (GO:0019373)7.90728528
8organic cation transport (GO:0015695)7.64961836
9regulation of fibrinolysis (GO:0051917)7.63213823
10omega-hydroxylase P450 pathway (GO:0097267)7.36049471
11complement activation, alternative pathway (GO:0006957)7.30725469
12negative regulation of fibrinolysis (GO:0051918)7.29826115
13regulation of protein activation cascade (GO:2000257)7.17388443
14cysteine metabolic process (GO:0006534)7.07700532
15glyoxylate metabolic process (GO:0046487)6.94843271
16regulation of complement activation (GO:0030449)6.74597792
17drug catabolic process (GO:0042737)6.42898129
18ethanol oxidation (GO:0006069)6.42291037
19cellular glucuronidation (GO:0052695)6.22289950
20protein carboxylation (GO:0018214)6.21418567
21peptidyl-glutamic acid carboxylation (GO:0017187)6.21418567
22quaternary ammonium group transport (GO:0015697)6.17671345
23exogenous drug catabolic process (GO:0042738)6.12141901
24response to mercury ion (GO:0046689)5.96494324
25urea metabolic process (GO:0019627)5.94999029
26uronic acid metabolic process (GO:0006063)5.92355284
27glucuronate metabolic process (GO:0019585)5.92355284
28fibrinolysis (GO:0042730)5.91221897
29erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)5.86421823
30L-phenylalanine catabolic process (GO:0006559)5.86421823
31erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)5.83982351
32L-phenylalanine metabolic process (GO:0006558)5.83982351
33aromatic amino acid family catabolic process (GO:0009074)5.79737528
34aspartate family amino acid catabolic process (GO:0009068)5.79344867
35blood coagulation, intrinsic pathway (GO:0007597)5.76616582
36* phosphate ion transport (GO:0006817)5.71660618
37indole-containing compound catabolic process (GO:0042436)5.62077674
38indolalkylamine catabolic process (GO:0046218)5.62077674
39tryptophan catabolic process (GO:0006569)5.62077674
40homocysteine metabolic process (GO:0050667)5.59628741
41negative regulation of cholesterol transport (GO:0032375)5.56344471
42negative regulation of sterol transport (GO:0032372)5.56344471
43short-chain fatty acid metabolic process (GO:0046459)5.54331896
44tricarboxylic acid metabolic process (GO:0072350)5.49434682
45excretion (GO:0007588)5.42177742
46nitrogen cycle metabolic process (GO:0071941)5.41166716
47fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)5.32895027
48nonribosomal peptide biosynthetic process (GO:0019184)5.32745392
49tryptophan metabolic process (GO:0006568)5.32443621
50oxidative demethylation (GO:0070989)5.29946781
51vitamin D metabolic process (GO:0042359)5.22035152
52ethanol metabolic process (GO:0006067)5.16556932
53triglyceride-rich lipoprotein particle remodeling (GO:0034370)5.13559083
54valine metabolic process (GO:0006573)5.12651868
55branched-chain amino acid metabolic process (GO:0009081)5.12624683
56bile acid metabolic process (GO:0008206)5.08985120
57serine family amino acid catabolic process (GO:0009071)5.07034471
58urea cycle (GO:0000050)5.06446442
592-oxoglutarate metabolic process (GO:0006103)4.94531812
60amino-acid betaine metabolic process (GO:0006577)4.92035386
61regulation of plasminogen activation (GO:0010755)4.91046562
62renal absorption (GO:0070293)4.89095732
63serine family amino acid metabolic process (GO:0009069)4.88985675
64cellular modified amino acid catabolic process (GO:0042219)4.84783229
65glutathione biosynthetic process (GO:0006750)4.84021665
66phenylpropanoid metabolic process (GO:0009698)4.81788033
67metanephric tubule development (GO:0072170)4.80899815
68metanephric nephron tubule development (GO:0072234)4.80899815
69regulation of triglyceride catabolic process (GO:0010896)4.80195735
70toxin transport (GO:1901998)4.74608136
71kynurenine metabolic process (GO:0070189)4.73543850
72glycine metabolic process (GO:0006544)4.73428892
73negative regulation of blood coagulation (GO:0030195)4.67839351
74negative regulation of hemostasis (GO:1900047)4.67839351
75cellular ketone body metabolic process (GO:0046950)4.66685305
76amino-acid betaine transport (GO:0015838)4.65758499
77carnitine transport (GO:0015879)4.65758499
78protein activation cascade (GO:0072376)4.60503082
79fatty acid beta-oxidation (GO:0006635)4.57570517
80negative regulation of protein activation cascade (GO:2000258)4.57517288
81acetyl-CoA metabolic process (GO:0006084)4.53109719
82imidazole-containing compound metabolic process (GO:0052803)4.49702012
83bile acid and bile salt transport (GO:0015721)4.44303650
84glutamate metabolic process (GO:0006536)4.44004029
85metanephric nephron epithelium development (GO:0072243)4.41576131
86high-density lipoprotein particle remodeling (GO:0034375)4.40303014
87modified amino acid transport (GO:0072337)4.38118924
88triglyceride homeostasis (GO:0070328)4.37622959
89acylglycerol homeostasis (GO:0055090)4.37622959
90branched-chain amino acid catabolic process (GO:0009083)4.37606532
91protein-lipid complex remodeling (GO:0034368)4.35369727
92macromolecular complex remodeling (GO:0034367)4.35369727
93plasma lipoprotein particle remodeling (GO:0034369)4.35369727
94phospholipid efflux (GO:0033700)4.34552967
95regulation of cholesterol esterification (GO:0010872)4.33953311
96carnitine metabolic process (GO:0009437)4.33782824
97negative regulation of coagulation (GO:0050819)4.33514763
98fructose metabolic process (GO:0006000)4.31729490
99* phosphate ion transmembrane transport (GO:0035435)4.31250972
100fatty acid oxidation (GO:0019395)4.29855715
101aromatic amino acid family metabolic process (GO:0009072)4.26567472
102S-adenosylmethionine metabolic process (GO:0046500)4.24671435
103proline metabolic process (GO:0006560)4.22519125
104lipid oxidation (GO:0034440)4.21690784
105negative regulation of wound healing (GO:0061045)4.21331770
106trivalent inorganic anion homeostasis (GO:0072506)4.20006827
107phosphate ion homeostasis (GO:0055062)4.20006827
108regulation of humoral immune response (GO:0002920)4.19679940
109cholesterol efflux (GO:0033344)4.19328547
110response to phenylpropanoid (GO:0080184)4.18689381
111alpha-amino acid catabolic process (GO:1901606)4.18444400
112cellular amino acid catabolic process (GO:0009063)4.17941405
113complement activation (GO:0006956)4.17693444
114tyrosine metabolic process (GO:0006570)4.15147191
115complement activation, classical pathway (GO:0006958)4.13525946
116sulfur amino acid catabolic process (GO:0000098)4.13100688
117serine family amino acid biosynthetic process (GO:0009070)4.09296297
118metanephric epithelium development (GO:0072207)4.02842170
119ketone body metabolic process (GO:1902224)4.02356274
120reverse cholesterol transport (GO:0043691)4.00606178
121indolalkylamine metabolic process (GO:0006586)3.98247403
122flavonoid metabolic process (GO:0009812)3.98046619
123negative regulation of lipase activity (GO:0060192)3.95255084
124acute-phase response (GO:0006953)3.92878913
125fatty acid catabolic process (GO:0009062)3.88449967
126intestinal cholesterol absorption (GO:0030299)3.87547779
127peptide biosynthetic process (GO:0043043)3.83694597
128negative regulation of complement activation (GO:0045916)3.82904536
129benzene-containing compound metabolic process (GO:0042537)3.82275416
130positive regulation of lipoprotein lipase activity (GO:0051006)3.82087752
131positive regulation of triglyceride lipase activity (GO:0061365)3.82087752
132alkaloid metabolic process (GO:0009820)3.79746882
133organic acid catabolic process (GO:0016054)3.79276813
134carboxylic acid catabolic process (GO:0046395)3.79276813
135positive regulation of hemostasis (GO:1900048)3.77620955
136positive regulation of blood coagulation (GO:0030194)3.77620955
137indole-containing compound metabolic process (GO:0042430)3.76403621
138hormone catabolic process (GO:0042447)3.75585945
139glycoside metabolic process (GO:0016137)3.74009884
140positive regulation of heterotypic cell-cell adhesion (GO:0034116)3.73348618
141monocarboxylic acid catabolic process (GO:0072329)3.71948196
142nephron tubule development (GO:0072080)3.71207940
143amine catabolic process (GO:0009310)3.67029488
144cellular biogenic amine catabolic process (GO:0042402)3.67029488
145arginine metabolic process (GO:0006525)3.66543598
146bile acid biosynthetic process (GO:0006699)3.63476413
147response to growth hormone (GO:0060416)3.62570651
148glutathione derivative biosynthetic process (GO:1901687)3.58821851
149glutathione derivative metabolic process (GO:1901685)3.58821851
150drug metabolic process (GO:0017144)3.58619538
151glutathione metabolic process (GO:0006749)3.58421562
152daunorubicin metabolic process (GO:0044597)3.55674685
153polyketide metabolic process (GO:0030638)3.55674685
154doxorubicin metabolic process (GO:0044598)3.55674685
155plasma lipoprotein particle clearance (GO:0034381)3.53622293
156aldehyde catabolic process (GO:0046185)3.53471354
157very-low-density lipoprotein particle assembly (GO:0034379)3.52929837
158vitamin transport (GO:0051180)3.52032135
159dicarboxylic acid metabolic process (GO:0043648)3.51532348
160cytolysis (GO:0019835)3.51253822
161peptide catabolic process (GO:0043171)3.50830410
162xenobiotic metabolic process (GO:0006805)3.46845403
163positive regulation of coagulation (GO:0050820)3.46819694
164biotin metabolic process (GO:0006768)3.45127714
165opsonization (GO:0008228)3.44548854
166NADH metabolic process (GO:0006734)3.44115539
167xenobiotic catabolic process (GO:0042178)3.43812469
168polyol transport (GO:0015791)3.34715737
169small molecule catabolic process (GO:0044282)3.31429543
170renal tubule development (GO:0061326)3.28445244
171L-ascorbic acid metabolic process (GO:0019852)3.27886420
172sodium-independent organic anion transport (GO:0043252)3.27524756
173oxaloacetate metabolic process (GO:0006107)3.27346105
174dicarboxylic acid biosynthetic process (GO:0043650)3.26809746

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* ESR1_17901129_ChIP-ChIP_LIVER_Mouse8.06981749
2RXR_22158963_ChIP-Seq_LIVER_Mouse6.54658910
3PPARA_22158963_ChIP-Seq_LIVER_Mouse5.54463575
4LXR_22158963_ChIP-Seq_LIVER_Mouse4.93823688
5PPARG_19300518_ChIP-PET_3T3-L1_Mouse4.72261240
6EGR1_23403033_ChIP-Seq_LIVER_Mouse3.56091496
7ESR1_21235772_ChIP-Seq_MCF-7_Human3.01649291
8FOXO1_23066095_ChIP-Seq_LIVER_Mouse2.99561026
9GATA1_22025678_ChIP-Seq_K562_Human2.94070931
10HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.88840212
11NR1I2_20693526_ChIP-Seq_LIVER_Mouse2.85945320
12TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.79789769
13CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.37331476
14ESRRB_18555785_ChIP-Seq_MESCs_Mouse2.24790184
15RARG_19884340_ChIP-ChIP_MEFs_Mouse2.18448460
16CEBPA_23403033_ChIP-Seq_LIVER_Mouse2.15090168
17CHD7_19251738_ChIP-ChIP_MESCs_Mouse2.13602293
18CLOCK_20551151_ChIP-Seq_293T_Human2.11729865
19TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.10781962
20TCF7L2_21901280_ChIP-Seq_H4IIE_Rat2.09428991
21AR_21909140_ChIP-Seq_LNCAP_Human2.02742312
22ESR2_21235772_ChIP-Seq_MCF-7_Human2.01009474
23TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.81956714
24TRIM28_21343339_ChIP-Seq_HEK293_Human1.81447674
25E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.80611405
26CDX2_20551321_ChIP-Seq_CACO-2_Human1.77985288
27* HNF4A_19822575_ChIP-Seq_HepG2_Human1.65411986
28FOXA2_19822575_ChIP-Seq_HepG2_Human1.59982112
29HTT_18923047_ChIP-ChIP_STHdh_Human1.59691805
30STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.57203131
31VDR_22108803_ChIP-Seq_LS180_Human1.56310974
32ESR1_20079471_ChIP-ChIP_T-47D_Human1.55931563
33ESR1_15608294_ChIP-ChIP_MCF-7_Human1.51836602
34GATA4_25053715_ChIP-Seq_YYC3_Human1.49598907
35NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.47964065
36PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.46748945
37* SOX2_27498859_Chip-Seq_STOMACH_Mouse1.46034459
38ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.44436405
39EGR1_19032775_ChIP-ChIP_M12_Human1.29858155
40RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.25059349
41NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.22778777
42FOXO3_23340844_ChIP-Seq_DLD1_Human1.22145487
43IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.20938369
44LXR_22292898_ChIP-Seq_THP-1_Human1.20680404
45GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.20650724
46ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.19919396
47STAT3_1855785_ChIP-Seq_MESCs_Mouse1.13138148
48THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.11740721
49IRF8_22096565_ChIP-ChIP_GC-B_Human1.11221134
50FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.11058429
51GATA6_25053715_ChIP-Seq_YYC3_Human1.09668566
52TP53_18474530_ChIP-ChIP_U2OS_Human1.07055853
53PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.05366502
54RACK7_27058665_Chip-Seq_MCF-7_Human1.03891491
55AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.01509651
56BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.99508013
57NFE2_27457419_Chip-Seq_LIVER_Mouse0.96795908
58FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.96046263
59PIAS1_25552417_ChIP-Seq_VCAP_Human0.94688292
60TBX20_22328084_ChIP-Seq_HEART_Mouse0.93580884
61TBX20_22080862_ChIP-Seq_HEART_Mouse0.93580884
62PPAR_26484153_Chip-Seq_NCI-H1993_Human0.92450315
63CDX2_19796622_ChIP-Seq_MESCs_Mouse0.91440646
64PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.89651434
65SOX2_20726797_ChIP-Seq_SW620_Human0.87244064
66SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.86470620
67MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.85994682
68SMAD3_21741376_ChIP-Seq_HESCs_Human0.85980922
69BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.83949974
70EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.83907501
71RXR_22108803_ChIP-Seq_LS180_Human0.83817696
72FOXA1_25552417_ChIP-Seq_VCAP_Human0.83473653
73CDX2_22108803_ChIP-Seq_LS180_Human0.83304741
74SALL4_18804426_ChIP-ChIP_XEN_Mouse0.83101601
75PCGF2_27294783_Chip-Seq_NPCs_Mouse0.81627052
76MYC_19915707_ChIP-ChIP_AK7_Human0.80248574
77Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.78951126
78NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.78889813
79NRF2_20460467_ChIP-Seq_MEFs_Mouse0.78889813
80ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.78825660
81TP63_17297297_ChIP-ChIP_HaCaT_Human0.78656591
82KAP1_22055183_ChIP-Seq_ESCs_Mouse0.77923184
83RAD21_21589869_ChIP-Seq_MESCs_Mouse0.77829541
84GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.77750760
85SUZ12_27294783_Chip-Seq_NPCs_Mouse0.76428147
86FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.75204236
87NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.74818988
88SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.74670770
89CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.74641378
90EZH2_27294783_Chip-Seq_NPCs_Mouse0.74625697
91GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.74406850
92SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.74396323
93P63_20808887_ChIP-Seq_KERATINOCYTES_Human0.74102323
94TP53_16413492_ChIP-PET_HCT116_Human0.73897452
95ERG_21242973_ChIP-ChIP_JURKAT_Human0.72997916
96SMAD4_21741376_ChIP-Seq_HESCs_Human0.72835752
97CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.72739549
98PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.72204405
99BCAT_22108803_ChIP-Seq_LS180_Human0.71779493
100TCF4_18268006_ChIP-ChIP_LS174T_Human0.71127047
101HNFA_21074721_ChIP-Seq_CACO-2_Human0.70614329
102GBX2_23144817_ChIP-Seq_PC3_Human0.67473582
103TAF2_19829295_ChIP-Seq_ESCs_Human0.67170723
104EP300_21415370_ChIP-Seq_HL-1_Mouse0.67166985
105CRX_20693478_ChIP-Seq_RETINA_Mouse0.66578510
106PHF8_20622853_ChIP-Seq_HELA_Human0.66280931
107CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.66151328
108TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.66028708
109TP63_23658742_ChIP-Seq_EP156T_Human0.65891856
110RAC3_21632823_ChIP-Seq_H3396_Human0.65346291
111GATA2_19941826_ChIP-Seq_K562_Human0.65270928
112NANOG_18692474_ChIP-Seq_MEFs_Mouse0.64927917
113NFYA_21822215_ChIP-Seq_K562_Human0.64673491
114SMAD1_18555785_Chip-Seq_ESCs_Mouse0.64433973
115EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.64150450
116P53_21459846_ChIP-Seq_SAOS-2_Human0.64024951
117AR_20517297_ChIP-Seq_VCAP_Human0.63415983
118ESRRB_18555785_Chip-Seq_ESCs_Mouse0.63177590
119SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.62381720
120CEBPB_22108803_ChIP-Seq_LS180_Human0.61878514
121RXRA_24833708_ChIP-Seq_LIVER_Mouse0.61474890
122SOX11_22085726_ChIP-Seq_ESNs_Mouse0.61447933
123SOX2_18692474_ChIP-Seq_MEFs_Mouse0.61411809
124ETV2_25802403_ChIP-Seq_MESCs_Mouse0.61293832
125CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.61275511
126SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.61214729
127KLF5_20875108_ChIP-Seq_MESCs_Mouse0.60510302
128CSB_26484114_Chip-Seq_FIBROBLAST_Human0.60351949
129FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.60337922
130TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.59953621
131ESET_19884257_ChIP-Seq_ESCs_Mouse0.59673417
132ER_23166858_ChIP-Seq_MCF-7_Human0.59561209
133CBP_21632823_ChIP-Seq_H3396_Human0.59206434
134RUNX1_27457419_Chip-Seq_LIVER_Mouse0.58899467
135ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.58829635
136OCT4_18555785_Chip-Seq_ESCs_Mouse0.58805713
137AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.58481590
138SMC4_20622854_ChIP-Seq_HELA_Human0.58364037
139STAT1_17558387_ChIP-Seq_HELA_Human0.58220817
140TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.58150929
141CREB1_26743006_Chip-Seq_LNCaP_Human0.56873647
142OCT4_21477851_ChIP-Seq_ESCs_Mouse0.56808145
143EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.56479385
144OCT4_20526341_ChIP-Seq_ESCs_Human0.56149785
145PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.55765507
146* SOX2_21211035_ChIP-Seq_LN229_Human0.55732302
147TCF4_22108803_ChIP-Seq_LS180_Human0.55678566
148CJUN_26792858_Chip-Seq_BT549_Human0.55666708
149PU1_27457419_Chip-Seq_LIVER_Mouse0.54221871
150DROSHA_22980978_ChIP-Seq_HELA_Human0.53956020
151ZFX_18555785_Chip-Seq_ESCs_Mouse0.53557985

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005360_urolithiasis8.23189603
2MP0002139_abnormal_hepatobiliary_system5.63960334
3MP0004043_abnormal_pH_regulation5.60243279
4MP0005332_abnormal_amino_acid4.82958073
5MP0004019_abnormal_vitamin_homeostasis4.74397540
6MP0003195_calcinosis4.42260614
7MP0002138_abnormal_hepatobiliary_system3.86423807
8MP0009643_abnormal_urine_homeostasis3.65915115
9MP0008875_abnormal_xenobiotic_pharmacok3.57598807
10MP0005365_abnormal_bile_salt3.40298510
11MP0001765_abnormal_ion_homeostasis3.29672690
12MP0005085_abnormal_gallbladder_physiolo3.24352792
13MP0003252_abnormal_bile_duct3.04725287
14MP0005636_abnormal_mineral_homeostasis2.88968044
15MP0001756_abnormal_urination2.88400733
16MP0002136_abnormal_kidney_physiology2.64647967
17MP0009697_abnormal_copulation2.45866968
18MP0003878_abnormal_ear_physiology2.34984195
19MP0005377_hearing/vestibular/ear_phenot2.34984195
20MP0001958_emphysema2.12652953
21MP0003806_abnormal_nucleotide_metabolis2.04493387
22MP0003186_abnormal_redox_activity1.75021915
23MP0005058_abnormal_lysosome_morphology1.71729261
24MP0005584_abnormal_enzyme/coenzyme_acti1.71326569
25MP0008961_abnormal_basal_metabolism1.62724454
26MP0005319_abnormal_enzyme/_coenzyme1.52526342
27MP0005451_abnormal_body_composition1.50095209
28MP0000538_abnormal_urinary_bladder1.49227959
29MP0001666_abnormal_nutrient_absorption1.42008860
30MP0005084_abnormal_gallbladder_morpholo1.37598845
31MP0003191_abnormal_cellular_cholesterol1.35158096
32MP0004885_abnormal_endolymph1.34723475
33MP0010329_abnormal_lipoprotein_level1.34237174
34MP0002876_abnormal_thyroid_physiology1.32309076
35MP0003300_gastrointestinal_ulcer1.31528961
36MP0002928_abnormal_bile_duct1.29558145
37MP0010368_abnormal_lymphatic_system1.29229002
38MP0001764_abnormal_homeostasis1.25600978
39MP0006036_abnormal_mitochondrial_physio1.23171219
40MP0002118_abnormal_lipid_homeostasis1.20196766
41MP0002168_other_aberrant_phenotype1.17262881
42MP0000230_abnormal_systemic_arterial1.11474324
43MP0005670_abnormal_white_adipose1.04957052
44MP0009053_abnormal_anal_canal1.04278669
45MP0005535_abnormal_body_temperature1.04183265
46MP0002135_abnormal_kidney_morphology0.99739151
47MP0000609_abnormal_liver_physiology0.99499073
48MP0008872_abnormal_physiological_respon0.95974983
49MP0002132_abnormal_respiratory_system0.89098800
50MP0001661_extended_life_span0.88097079
51MP0001915_intracranial_hemorrhage0.88016973
52MP0004147_increased_porphyrin_level0.87687730
53MP0005666_abnormal_adipose_tissue0.85128538
54MP0003638_abnormal_response/metabolism_0.82454235
55MP0004264_abnormal_extraembryonic_tissu0.81825329
56MP0009642_abnormal_blood_homeostasis0.81574860
57MP0002896_abnormal_bone_mineralization0.80973624
58MP0009764_decreased_sensitivity_to0.80474625
59MP0005083_abnormal_biliary_tract0.78678076
60MP0005220_abnormal_exocrine_pancreas0.78669786
61MP0010234_abnormal_vibrissa_follicle0.77296141
62MP0003283_abnormal_digestive_organ0.70797644
63MP0005395_other_phenotype0.69283486
64MP0000598_abnormal_liver_morphology0.67777203
65MP0002089_abnormal_postnatal_growth/wei0.67629607
66MP0003172_abnormal_lysosome_physiology0.64237769
67MP0009763_increased_sensitivity_to0.64103336
68MP0003011_delayed_dark_adaptation0.63970991
69MP0008469_abnormal_protein_level0.63346477
70MP0002796_impaired_skin_barrier0.62180289
71MP0003656_abnormal_erythrocyte_physiolo0.62040981
72MP0003959_abnormal_lean_body0.61825046
73MP0003646_muscle_fatigue0.60769881
74MP0005464_abnormal_platelet_physiology0.57060296
75MP0002078_abnormal_glucose_homeostasis0.55578048
76MP0005408_hypopigmentation0.55203482
77MP0006035_abnormal_mitochondrial_morpho0.54318777
78MP0003329_amyloid_beta_deposits0.52401522
79MP0002909_abnormal_adrenal_gland0.51008836
80MP0004782_abnormal_surfactant_physiolog0.50671600
81MP0005187_abnormal_penis_morphology0.49116912
82MP0000747_muscle_weakness0.48936300
83MP0003690_abnormal_glial_cell0.45876046
84MP0000371_diluted_coat_color0.45869257
85MP0009840_abnormal_foam_cell0.45326031
86MP0003953_abnormal_hormone_level0.44452566
87MP0005334_abnormal_fat_pad0.42953915
88MP0005266_abnormal_metabolism0.41630117
89MP0005165_increased_susceptibility_to0.41446489
90MP0002282_abnormal_trachea_morphology0.40886409
91MP0008874_decreased_physiological_sensi0.40851378
92MP0005501_abnormal_skin_physiology0.40068374
93MP0001944_abnormal_pancreas_morphology0.38622550
94MP0002069_abnormal_eating/drinking_beha0.37561250
95MP0005376_homeostasis/metabolism_phenot0.37461509
96MP0002115_abnormal_skeleton_extremities0.36746513
97MP0000604_amyloidosis0.36661089
98MP0003795_abnormal_bone_structure0.34891900
99MP0009765_abnormal_xenobiotic_induced0.34594198
100MP0003879_abnormal_hair_cell0.33677781
101MP0000566_synostosis0.33649992
102MP0002971_abnormal_brown_adipose0.33537662
103MP0003868_abnormal_feces_composition0.33520968
104MP0000249_abnormal_blood_vessel0.33147223
105MP0009672_abnormal_birth_weight0.32659166
106MP0009785_altered_susceptibility_to0.32600735
107MP0005023_abnormal_wound_healing0.32491212
108MP0002332_abnormal_exercise_endurance0.32345260
109MP0005167_abnormal_blood-brain_barrier0.32303296
110MP0002249_abnormal_larynx_morphology0.31592381
111MP0005448_abnormal_energy_balance0.31475025
112MP0005375_adipose_tissue_phenotype0.31457886
113MP0003941_abnormal_skin_development0.31293161
114MP0005164_abnormal_response_to0.31202406
115MP0002998_abnormal_bone_remodeling0.30886030
116MP0001485_abnormal_pinna_reflex0.30781459
117MP0002098_abnormal_vibrissa_morphology0.30291450
118MP0003724_increased_susceptibility_to0.30113605
119MP0003221_abnormal_cardiomyocyte_apopto0.30084813
120MP0004130_abnormal_muscle_cell0.30072987
121MP0010386_abnormal_urinary_bladder0.29539483
122MP0003705_abnormal_hypodermis_morpholog0.29216225
123MP0005166_decreased_susceptibility_to0.28818029
124MP0002090_abnormal_vision0.28696014
125MP0003075_altered_response_to0.26770848
126MP0004272_abnormal_basement_membrane0.26491463
127MP0001545_abnormal_hematopoietic_system0.26357983
128MP0005397_hematopoietic_system_phenotyp0.26357983
129MP0000467_abnormal_esophagus_morphology0.25738782
130MP0001845_abnormal_inflammatory_respons0.25639056
131MP0000920_abnormal_myelination0.25563029
132MP0001663_abnormal_digestive_system0.25324203
133MP0003183_abnormal_peptide_metabolism0.24942363
134MP0004742_abnormal_vestibular_system0.24927145
135MP0000163_abnormal_cartilage_morphology0.24837171
136MP0005197_abnormal_uvea_morphology0.24729866

Predicted human phenotypes

RankGene SetZ-score
1Deep venous thrombosis (HP:0002625)9.20650243
2Prolonged partial thromboplastin time (HP:0003645)8.16402923
3Complement deficiency (HP:0004431)7.96185826
4Increased circulating renin level (HP:0000848)7.49213889
5Hypokalemic alkalosis (HP:0001949)7.05298020
6Hypobetalipoproteinemia (HP:0003563)6.97465673
7Metabolic alkalosis (HP:0200114)6.95864763
8Gout (HP:0001997)6.85203945
9Hypomagnesemia (HP:0002917)6.72626005
10Hyperactive renin-angiotensin system (HP:0000841)6.58888830
11Abnormality of complement system (HP:0005339)6.27423986
12Polyuria (HP:0000103)6.23454098
13Abnormality of chloride homeostasis (HP:0011422)5.92379323
14Abnormal urine output (HP:0012590)5.91943667
15Conjugated hyperbilirubinemia (HP:0002908)5.69034174
16Abnormality of magnesium homeostasis (HP:0004921)5.67746054
17Joint hemorrhage (HP:0005261)5.62733357
18Abnormality of renal excretion (HP:0011036)5.57310556
19Proximal tubulopathy (HP:0000114)5.25931840
20Systemic lupus erythematosus (HP:0002725)5.19761238
21Hyperuricemia (HP:0002149)5.05447017
22Increased purine levels (HP:0004368)5.05447017
23Polydipsia (HP:0001959)5.00394269
24Abnormal drinking behavior (HP:0030082)5.00394269
25Hyperglycinuria (HP:0003108)4.94615528
26Abnormality of glutamine family amino acid metabolism (HP:0010902)4.92947047
27Alkalosis (HP:0001948)4.80451444
28Tetany (HP:0001281)4.80397770
29Abnormality of the common coagulation pathway (HP:0010990)4.79111724
30Glomerulonephritis (HP:0000099)4.72681868
31Hyperlipoproteinemia (HP:0010980)4.67617387
32Abnormality of purine metabolism (HP:0004352)4.56715304
33Renal salt wasting (HP:0000127)4.55534620
34Abnormality of renin-angiotensin system (HP:0000847)4.54773243
35Hyperaldosteronism (HP:0000859)4.46678508
36Hypolipoproteinemia (HP:0010981)4.29518742
37Abnormality of glycine metabolism (HP:0010895)4.19845126
38Abnormality of serine family amino acid metabolism (HP:0010894)4.19845126
39Spontaneous abortion (HP:0005268)4.18786220
40Ketoacidosis (HP:0001993)4.02882987
41Abnormality of pyrimidine metabolism (HP:0004353)3.92214100
42Generalized aminoaciduria (HP:0002909)3.90407969
43Hypercalciuria (HP:0002150)3.69000177
44Ketosis (HP:0001946)3.68874343
45Abnormality of the level of lipoprotein cholesterol (HP:0010979)3.63129496
46Recurrent gram-negative bacterial infections (HP:0005420)3.58579562
47Nephritis (HP:0000123)3.56410664
48Renal tubular acidosis (HP:0001947)3.52093867
49Abnormality of urine glucose concentration (HP:0011016)3.51685835
50Glycosuria (HP:0003076)3.51685835
51Abnormality of nucleobase metabolism (HP:0010932)3.49370497
52Hypokalemia (HP:0002900)3.46860554
53Abnormality of the intrinsic pathway (HP:0010989)3.43039935
54Abnormality of aspartate family amino acid metabolism (HP:0010899)3.31255312
55Abnormality of fatty-acid metabolism (HP:0004359)3.25209321
56Fat malabsorption (HP:0002630)3.21714397
57Hyperglycinemia (HP:0002154)3.17598157
58Hypoalphalipoproteinemia (HP:0003233)3.10752193
59Hyperphosphaturia (HP:0003109)3.05805645
60Abnormality of aromatic amino acid family metabolism (HP:0004338)3.04351768
61Osteomalacia (HP:0002749)2.96116551
62Abnormality of proline metabolism (HP:0010907)2.94228067
63Hydroxyprolinuria (HP:0003080)2.94228067
64Delayed CNS myelination (HP:0002188)2.93235060
65Abnormality of potassium homeostasis (HP:0011042)2.90301675
66Hyperammonemia (HP:0001987)2.89331813
67Gingival bleeding (HP:0000225)2.86267524
68Abnormality of methionine metabolism (HP:0010901)2.85104924
69Abnormal urine phosphate concentration (HP:0012599)2.84782033
70Hypercholesterolemia (HP:0003124)2.84564957
71Nephrocalcinosis (HP:0000121)2.82800079
72Nephrolithiasis (HP:0000787)2.78740934
73Vascular calcification (HP:0004934)2.76851973
74Mitral stenosis (HP:0001718)2.70487091
75Abnormality of sulfur amino acid metabolism (HP:0004339)2.67271478
76Delayed epiphyseal ossification (HP:0002663)2.65325593
77Hemorrhage of the eye (HP:0011885)2.57538869
78Metabolic acidosis (HP:0001942)2.55483201
79Rickets (HP:0002748)2.55407423
80Abnormality of dicarboxylic acid metabolism (HP:0010995)2.53649343
81Dicarboxylic aciduria (HP:0003215)2.53649343
82Hypophosphatemia (HP:0002148)2.51853950
83Epidermoid cyst (HP:0200040)2.48059529
84Enlarged kidneys (HP:0000105)2.46477907
85Cardiovascular calcification (HP:0011915)2.46432728
86Menorrhagia (HP:0000132)2.44527009
87Dehydration (HP:0001944)2.43059741
88Hyperbilirubinemia (HP:0002904)2.42985609
89Fair hair (HP:0002286)2.42774769
90Vomiting (HP:0002013)2.42474205
91Steatorrhea (HP:0002570)2.34612673
92Thrombophlebitis (HP:0004418)2.33779318
93Vacuolated lymphocytes (HP:0001922)2.30869978
94Malnutrition (HP:0004395)2.30465316
95Widely patent fontanelles and sutures (HP:0004492)2.29015890
96Lethargy (HP:0001254)2.25303498
97Confusion (HP:0001289)2.24368112
98Xanthomatosis (HP:0000991)2.23433782
99Purpura (HP:0000979)2.21929658
100Abnormality of sodium homeostasis (HP:0010931)2.21060642
101Hyponatremia (HP:0002902)2.19064439
102Metaphyseal cupping (HP:0003021)2.17148851
103Renal tubular dysfunction (HP:0000124)2.16753850
104Abnormal enzyme/coenzyme activity (HP:0012379)2.15372528
105Neonatal hypoglycemia (HP:0001998)2.10776339
106Potter facies (HP:0002009)2.09890119
107Facial shape deformation (HP:0011334)2.09890119
108Intrahepatic cholestasis (HP:0001406)2.09218290
109Abnormality of renal resorption (HP:0011038)2.08744720
110Arthropathy (HP:0003040)2.06820639
111Reduced antithrombin III activity (HP:0001976)2.06072419
112Abnormality of alkaline phosphatase activity (HP:0004379)2.05612537
113Abnormality of vitamin metabolism (HP:0100508)2.01915643
114Focal segmental glomerulosclerosis (HP:0000097)2.01630289
115Abnormality of serum amino acid levels (HP:0003112)2.01311763
116Chondrocalcinosis (HP:0000934)2.01067157
117Tubulointerstitial fibrosis (HP:0005576)1.99675819
118Methylmalonic aciduria (HP:0012120)1.99203300
119Adrenal overactivity (HP:0002717)1.99146040
120Pulmonary embolism (HP:0002204)1.93179984
121Bilateral sensorineural hearing impairment (HP:0008619)1.91405453
122Abnormality of monocarboxylic acid metabolism (HP:0010996)1.90714066
123Irritability (HP:0000737)1.89986708
124Abnormal tarsal ossification (HP:0008369)1.88819352
125Hypoglycemic coma (HP:0001325)1.88544575
126Abnormality of Sharpey fibers (HP:0100685)1.87926703
127Tubular atrophy (HP:0000092)1.87001037
128Nausea (HP:0002018)1.86945368
129Abnormality of the Achilles tendon (HP:0005109)1.85621300
130Impaired platelet aggregation (HP:0003540)1.84081221
131Abnormal platelet function (HP:0011869)1.84081221
132Neonatal onset (HP:0003623)1.83214827
133Thin bony cortex (HP:0002753)1.79695969
134Sensorimotor neuropathy (HP:0007141)1.78561911
135Glomerulosclerosis (HP:0000096)1.75044882
136Lymphangioma (HP:0100764)1.74651659
137Spastic diplegia (HP:0001264)1.70404745
138Elevated alkaline phosphatase (HP:0003155)1.69823047
139Hepatocellular carcinoma (HP:0001402)1.68226220
140Late onset (HP:0003584)1.66540721
141Hypotension (HP:0002615)1.65887664
142Hypophosphatemic rickets (HP:0004912)1.65169399

Predicted kinase interactions (KEA)

RankGene SetZ-score
1WNK38.51077124
2WNK48.47722929
3OXSR17.54826784
4STK394.25135755
5BCKDK3.34624706
6STK38L2.36979606
7PIK3CA2.21822305
8PDK41.91264970
9PDK31.91264970
10SGK4941.83051651
11SGK2231.83051651
12NEK11.82252138
13WNK11.72485047
14FGFR31.66761141
15NTRK31.45687039
16FGFR21.43344758
17MST1R1.40902404
18PDK21.39934859
19FGFR41.26631628
20STK381.21131370
21PDGFRA1.13404911
22SGK31.09205373
23SGK21.07717954
24MST40.98366813
25PINK10.90812190
26LRRK20.90399465
27ICK0.86042465
28ERN10.81902457
29GRK60.78185303
30EPHA20.76763096
31GSK3A0.74818871
32EPHB10.74210386
33MAP3K70.73169150
34INSRR0.67247293
35TIE10.61507817
36MAP3K30.61389716
37TRPM70.61340708
38CSF1R0.59750781
39ABL20.59108579
40DDR20.58573176
41MAPK110.58007584
42PTK20.56704159
43ADRBK20.56305026
44PRKAA10.55908049
45SGK10.54945379
46JAK10.53960851
47PTK60.53917553
48CDK120.53677101
49TGFBR20.52155563
50DYRK1B0.51938150
51PRKACB0.49605674
52PRKG10.49533199
53FRK0.48000794
54PRKAA20.46774464
55PRKCB0.46548173
56TNK20.45945974
57ERBB40.45780098
58PDPK10.44741632
59TRIB30.44023227
60FGFR10.43630039
61MET0.43103370
62CSNK1A10.42175664
63PRKCE0.38190053
64GRK10.37629411
65LATS10.37426562
66SIK10.37124907
67PRKCZ0.36983758
68PAK40.36339195
69CSNK1E0.34807596
70MAP3K140.34775704
71CDC42BPA0.34519335
72PDGFRB0.34089035
73ZAP700.33715016
74PAK30.33610592
75FER0.31849561
76TAOK30.31597250
77RIPK10.30942027
78CSNK1D0.29977373
79PDK10.29700017
80PRKG20.29496720
81TBK10.28792828
82MAPK100.27194458
83PRKCI0.26689972
84CAMKK20.26054741
85MAP2K40.25327939
86STK100.25039599
87PRKACG0.25012092
88JAK20.24819669
89TXK0.24812678
90STK110.24751263
91CDK60.24541069
92RET0.23970363
93CSNK2A20.23900957
94MAP3K20.22230883
95PTK2B0.21581372
96PRKCD0.21373542
97MAPK150.21175137
98CSNK2A10.20513287
99ACVR1B0.20419477
100MYLK0.20133123
101PRKD20.20131853
102NEK90.18537326
103IRAK20.17768013
104NTRK10.17736600
105MAP2K30.17220256
106MAPK70.17088558
107PRKCH0.15645938
108BMX0.15326716
109AKT20.15172771
110PRKCA0.14916561
111NME20.14198168
112EPHA40.12255400
113MAPK120.12227214
114MAP3K110.11834276
115PRKACA0.11235098
116DAPK20.10838373
117PIK3CG0.09849094
118PIM10.09810736
119PKN20.08521273
120CSK0.07192810
121MAPK40.06994494
122PRKCQ0.06633126
123KDR0.05759622
124ERBB20.05489296
125IGF1R0.05448583
126IRAK30.05271995
127MINK10.05106756
128INSR0.04770532
129TYK20.04658928
130MTOR0.04602801
131PRKCG0.04553461
132IRAK10.04052589
133SCYL20.02816188
134SRC0.02214592
135ROCK10.02156958
136CAMK40.01253631
137RPS6KA30.00803495
138MAP2K60.00517794

Predicted pathways (KEGG)

RankGene SetZ-score
1Butanoate metabolism_Homo sapiens_hsa006503.61341503
2Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.36967260
3Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006303.25929877
4Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.24802170
5Valine, leucine and isoleucine degradation_Homo sapiens_hsa002803.20829151
6Cyanoamino acid metabolism_Homo sapiens_hsa004603.18800435
7Propanoate metabolism_Homo sapiens_hsa006403.07470333
8Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.99967170
92-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.73607722
10Pentose and glucuronate interconversions_Homo sapiens_hsa000402.70930981
11Peroxisome_Homo sapiens_hsa041462.56102788
12Fatty acid degradation_Homo sapiens_hsa000712.53538927
13Tryptophan metabolism_Homo sapiens_hsa003802.49619743
14Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.37127438
15Pyruvate metabolism_Homo sapiens_hsa006202.28015102
16Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.21037744
17Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.15798686
18beta-Alanine metabolism_Homo sapiens_hsa004101.99225213
19Primary bile acid biosynthesis_Homo sapiens_hsa001201.98976397
20Vitamin digestion and absorption_Homo sapiens_hsa049771.95363055
21Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.92532729
22Fatty acid metabolism_Homo sapiens_hsa012121.87877071
23Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.84879002
24Nitrogen metabolism_Homo sapiens_hsa009101.78510118
25Bile secretion_Homo sapiens_hsa049761.76140926
26Arginine biosynthesis_Homo sapiens_hsa002201.71442079
27Sulfur metabolism_Homo sapiens_hsa009201.68415705
28Collecting duct acid secretion_Homo sapiens_hsa049661.65973169
29Carbon metabolism_Homo sapiens_hsa012001.65378668
30Linoleic acid metabolism_Homo sapiens_hsa005911.54124058
31PPAR signaling pathway_Homo sapiens_hsa033201.50001408
32Glutathione metabolism_Homo sapiens_hsa004801.47313715
33Arginine and proline metabolism_Homo sapiens_hsa003301.35035083
34Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.34513902
35Lysine degradation_Homo sapiens_hsa003101.30944657
36Selenocompound metabolism_Homo sapiens_hsa004501.27844363
37Histidine metabolism_Homo sapiens_hsa003401.23694708
38Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.20478962
39Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.19579505
40Vitamin B6 metabolism_Homo sapiens_hsa007501.18419057
41Biosynthesis of amino acids_Homo sapiens_hsa012301.13892607
42Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.11668200
43Phenylalanine metabolism_Homo sapiens_hsa003601.11655886
44Starch and sucrose metabolism_Homo sapiens_hsa005001.11353143
45Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.08602764
46Folate biosynthesis_Homo sapiens_hsa007901.00363060
47Protein digestion and absorption_Homo sapiens_hsa049740.97285663
48Other glycan degradation_Homo sapiens_hsa005110.97203135
49Mineral absorption_Homo sapiens_hsa049780.95137699
50Cysteine and methionine metabolism_Homo sapiens_hsa002700.95033162
51Prion diseases_Homo sapiens_hsa050200.91877095
52Fatty acid elongation_Homo sapiens_hsa000620.91765361
53Glycerolipid metabolism_Homo sapiens_hsa005610.90045602
54Chemical carcinogenesis_Homo sapiens_hsa052040.89794689
55Steroid hormone biosynthesis_Homo sapiens_hsa001400.87858223
56Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.85351673
57Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.84928086
58Drug metabolism - other enzymes_Homo sapiens_hsa009830.77974671
59Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.75229672
60Fructose and mannose metabolism_Homo sapiens_hsa000510.74237004
61Maturity onset diabetes of the young_Homo sapiens_hsa049500.69523254
62Retinol metabolism_Homo sapiens_hsa008300.66941984
63Pentose phosphate pathway_Homo sapiens_hsa000300.63483146
64Renin-angiotensin system_Homo sapiens_hsa046140.62331845
65Tyrosine metabolism_Homo sapiens_hsa003500.56503198
66Metabolic pathways_Homo sapiens_hsa011000.54705660
67Steroid biosynthesis_Homo sapiens_hsa001000.51893236
68ABC transporters_Homo sapiens_hsa020100.49712942
69Oxidative phosphorylation_Homo sapiens_hsa001900.49430419
70Complement and coagulation cascades_Homo sapiens_hsa046100.47746257
71Carbohydrate digestion and absorption_Homo sapiens_hsa049730.46965474
72Lysosome_Homo sapiens_hsa041420.45034253
73Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.41749926
74Sulfur relay system_Homo sapiens_hsa041220.39923294
75Glycosaminoglycan degradation_Homo sapiens_hsa005310.38314226
76Thyroid hormone synthesis_Homo sapiens_hsa049180.38215516
77Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.33605998
78Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.27663258
79Gastric acid secretion_Homo sapiens_hsa049710.22301947
80Pertussis_Homo sapiens_hsa051330.20526130
81Parkinsons disease_Homo sapiens_hsa050120.20476713
82Arachidonic acid metabolism_Homo sapiens_hsa005900.16922421
83Caffeine metabolism_Homo sapiens_hsa002320.16243996
84Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.15382279
85Insulin resistance_Homo sapiens_hsa049310.12251009
86Adipocytokine signaling pathway_Homo sapiens_hsa049200.12092214
87Galactose metabolism_Homo sapiens_hsa000520.11470846
88African trypanosomiasis_Homo sapiens_hsa051430.11052128
89Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.10761808
90Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.10217754
91Vibrio cholerae infection_Homo sapiens_hsa051100.10207576
92One carbon pool by folate_Homo sapiens_hsa006700.09700542
93Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.06480264
94Choline metabolism in cancer_Homo sapiens_hsa052310.04969039
95Fatty acid biosynthesis_Homo sapiens_hsa000610.04052629
96Fat digestion and absorption_Homo sapiens_hsa049750.04027140
97Synaptic vesicle cycle_Homo sapiens_hsa047210.03511954
98Systemic lupus erythematosus_Homo sapiens_hsa053220.02909155
99Staphylococcus aureus infection_Homo sapiens_hsa051500.02501565
100AMPK signaling pathway_Homo sapiens_hsa041520.00852796
101Insulin signaling pathway_Homo sapiens_hsa04910-0.1881134
102Ovarian steroidogenesis_Homo sapiens_hsa04913-0.1829714
103Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524-0.1724401
104ECM-receptor interaction_Homo sapiens_hsa04512-0.1400887
105Circadian rhythm_Homo sapiens_hsa04710-0.1357827
106Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520-0.1283463
107Serotonergic synapse_Homo sapiens_hsa04726-0.0831685
108Amoebiasis_Homo sapiens_hsa05146-0.0626185
109Ether lipid metabolism_Homo sapiens_hsa00565-0.0559823
110N-Glycan biosynthesis_Homo sapiens_hsa00510-0.0488159
111Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604-0.0444505
112Cardiac muscle contraction_Homo sapiens_hsa04260-0.0443221
113Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962-0.0408711
114Alzheimers disease_Homo sapiens_hsa05010-0.0214812
115Sphingolipid metabolism_Homo sapiens_hsa00600-0.0151355
116Glucagon signaling pathway_Homo sapiens_hsa04922-0.0125774
117alpha-Linolenic acid metabolism_Homo sapiens_hsa00592-0.0117152
118Glycerophospholipid metabolism_Homo sapiens_hsa00564-0.0077016

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