SLC17A3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is a voltage-driven transporter that excretes intracellular urate and organic anions from the blood into renal tubule cells. Two transcript variants encoding different isoforms have been found for this gene. The longer isoform is a plasma membrane protein with transporter activity while the shorter isoform localizes to the endoplasmic reticulum. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1epoxygenase P450 pathway (GO:0019373)7.49354222
2L-phenylalanine catabolic process (GO:0006559)7.36747336
3erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)7.36747336
4L-phenylalanine metabolic process (GO:0006558)7.13348136
5erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)7.13348136
6glyoxylate metabolic process (GO:0046487)6.96739132
7aromatic amino acid family catabolic process (GO:0009074)6.90194831
8lysine metabolic process (GO:0006553)6.83977916
9lysine catabolic process (GO:0006554)6.83977916
10omega-hydroxylase P450 pathway (GO:0097267)6.69906464
11cysteine metabolic process (GO:0006534)6.67158318
12tryptophan catabolic process (GO:0006569)6.49267371
13indole-containing compound catabolic process (GO:0042436)6.49267371
14indolalkylamine catabolic process (GO:0046218)6.49267371
15* urate metabolic process (GO:0046415)6.34990072
16* drug transmembrane transport (GO:0006855)6.25173309
17tryptophan metabolic process (GO:0006568)6.11229631
18kynurenine metabolic process (GO:0070189)5.87042764
19fibrinolysis (GO:0042730)5.69544490
20fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)5.64598627
21drug catabolic process (GO:0042737)5.61153346
22serine family amino acid catabolic process (GO:0009071)5.53380904
23blood coagulation, intrinsic pathway (GO:0007597)5.50079222
24homocysteine metabolic process (GO:0050667)5.45042460
25bile acid biosynthetic process (GO:0006699)5.35966448
26exogenous drug catabolic process (GO:0042738)5.28936258
27* drug transport (GO:0015893)5.26887112
28sulfur amino acid catabolic process (GO:0000098)5.14826493
29amino-acid betaine metabolic process (GO:0006577)5.09644060
30aromatic amino acid family metabolic process (GO:0009072)5.03391479
31serine family amino acid metabolic process (GO:0009069)4.93041897
32phenylpropanoid metabolic process (GO:0009698)4.89928263
33cellular ketone body metabolic process (GO:0046950)4.87160969
34short-chain fatty acid metabolic process (GO:0046459)4.86992973
35cellular modified amino acid catabolic process (GO:0042219)4.81620976
36aspartate family amino acid catabolic process (GO:0009068)4.79994927
37alpha-amino acid catabolic process (GO:1901606)4.79698519
38oxidative demethylation (GO:0070989)4.78714076
39regulation of plasminogen activation (GO:0010755)4.69253544
40organic cation transport (GO:0015695)4.68804838
41glutamate metabolic process (GO:0006536)4.62914641
42alpha-linolenic acid metabolic process (GO:0036109)4.60121857
43indolalkylamine metabolic process (GO:0006586)4.59072213
44cellular amino acid catabolic process (GO:0009063)4.58462994
45* phosphate ion transmembrane transport (GO:0035435)4.56524610
46urea metabolic process (GO:0019627)4.56300803
47urea cycle (GO:0000050)4.56300803
48negative regulation of blood coagulation (GO:0030195)4.51975930
49negative regulation of hemostasis (GO:1900047)4.51975930
50serine family amino acid biosynthetic process (GO:0009070)4.47201518
51response to mercury ion (GO:0046689)4.43477876
52bile acid metabolic process (GO:0008206)4.41106871
53amine catabolic process (GO:0009310)4.39336574
54cellular biogenic amine catabolic process (GO:0042402)4.39336574
55acetyl-CoA metabolic process (GO:0006084)4.37498617
56benzene-containing compound metabolic process (GO:0042537)4.33774803
572-oxoglutarate metabolic process (GO:0006103)4.33024710
58ethanol metabolic process (GO:0006067)4.31589946
59tyrosine metabolic process (GO:0006570)4.29654238
60negative regulation of coagulation (GO:0050819)4.27454424
61protein activation cascade (GO:0072376)4.26746384
62nitrogen cycle metabolic process (GO:0071941)4.26547757
63valine metabolic process (GO:0006573)4.26228703
64aminoglycoside antibiotic metabolic process (GO:0030647)4.25526804
65triglyceride-rich lipoprotein particle remodeling (GO:0034370)4.23971273
66ketone body metabolic process (GO:1902224)4.21199977
67S-adenosylmethionine metabolic process (GO:0046500)4.16230040
68fatty acid beta-oxidation (GO:0006635)4.15656569
69negative regulation of wound healing (GO:0061045)4.13321613
70negative regulation of protein activation cascade (GO:2000258)4.12245370
71aldehyde catabolic process (GO:0046185)4.11173105
72glycine metabolic process (GO:0006544)4.10473674
73branched-chain amino acid metabolic process (GO:0009081)4.09521299
74quaternary ammonium group transport (GO:0015697)4.07230025
75carboxylic acid catabolic process (GO:0046395)4.05958340
76organic acid catabolic process (GO:0016054)4.05958340
77fatty acid oxidation (GO:0019395)4.04975178
78coenzyme catabolic process (GO:0009109)4.03110492
79carnitine metabolic process (GO:0009437)4.03106098
80protein carboxylation (GO:0018214)4.00536924
81peptidyl-glutamic acid carboxylation (GO:0017187)4.00536924
82regulation of humoral immune response (GO:0002920)3.99930212
83cellular glucuronidation (GO:0052695)3.99007039
84dicarboxylic acid biosynthetic process (GO:0043650)3.98167723
85lipid oxidation (GO:0034440)3.97240351
86complement activation, alternative pathway (GO:0006957)3.96468458
87tricarboxylic acid metabolic process (GO:0072350)3.95410033
88negative regulation of fibrinolysis (GO:0051918)3.94449060
89ethanol oxidation (GO:0006069)3.93254398
90complement activation (GO:0006956)3.90715846
91hormone catabolic process (GO:0042447)3.89987321
92complement activation, classical pathway (GO:0006958)3.89552167
93regulation of protein activation cascade (GO:2000257)3.84884663
94artery smooth muscle contraction (GO:0014824)3.83394078
95sodium-independent organic anion transport (GO:0043252)3.81892704
96monocarboxylic acid catabolic process (GO:0072329)3.81724294
97branched-chain amino acid catabolic process (GO:0009083)3.80957460
98uronic acid metabolic process (GO:0006063)3.80760092
99glucuronate metabolic process (GO:0019585)3.80760092
100fatty acid catabolic process (GO:0009062)3.78748188
101* phosphate ion transport (GO:0006817)3.78539606
102regulation of fibrinolysis (GO:0051917)3.74980259
103negative regulation of complement activation (GO:0045916)3.73995736
104regulation of cholesterol homeostasis (GO:2000188)3.73709620
105drug metabolic process (GO:0017144)3.71064512
106positive regulation of blood coagulation (GO:0030194)3.70380233
107positive regulation of hemostasis (GO:1900048)3.70380233
108alkaloid metabolic process (GO:0009820)3.69352756
109negative regulation of cholesterol transport (GO:0032375)3.68214080
110negative regulation of sterol transport (GO:0032372)3.68214080
111high-density lipoprotein particle remodeling (GO:0034375)3.67116009
112metanephric tubule development (GO:0072170)3.67001976
113metanephric nephron tubule development (GO:0072234)3.67001976
114indole-containing compound metabolic process (GO:0042430)3.66084207
115tonic smooth muscle contraction (GO:0014820)3.64151745
116metanephric nephron epithelium development (GO:0072243)3.62617423
117steroid catabolic process (GO:0006706)3.62254498
118regulation of complement activation (GO:0030449)3.61909262
119phospholipid efflux (GO:0033700)3.59278213
120protein-lipid complex remodeling (GO:0034368)3.57943575
121macromolecular complex remodeling (GO:0034367)3.57943575
122plasma lipoprotein particle remodeling (GO:0034369)3.57943575
123fructose metabolic process (GO:0006000)3.57638273
124positive regulation of triglyceride lipase activity (GO:0061365)3.55546658
125positive regulation of lipoprotein lipase activity (GO:0051006)3.55546658
126acylglycerol homeostasis (GO:0055090)3.53868946
127triglyceride homeostasis (GO:0070328)3.53868946
128acute-phase response (GO:0006953)3.51663919
129nonribosomal peptide biosynthetic process (GO:0019184)3.51118554
130bile acid and bile salt transport (GO:0015721)3.49020706
131regulation of bile acid biosynthetic process (GO:0070857)3.47992373
132small molecule catabolic process (GO:0044282)3.47308998
133arginine metabolic process (GO:0006525)3.46529398
134regulation of cholesterol esterification (GO:0010872)3.45904988
135dicarboxylic acid metabolic process (GO:0043648)3.45382232
136flavonoid metabolic process (GO:0009812)3.45143047
137vitamin D metabolic process (GO:0042359)3.44620319
138negative regulation of lipase activity (GO:0060192)3.43667478
139regulation of triglyceride catabolic process (GO:0010896)3.42465560
140xenobiotic metabolic process (GO:0006805)3.41130568
141negative regulation of metanephros development (GO:0072217)3.40538116
142imidazole-containing compound metabolic process (GO:0052803)3.40422113
143positive regulation of coagulation (GO:0050820)3.39783981
144regulation of apoptotic process involved in morphogenesis (GO:1902337)3.38564519
145response to phenylpropanoid (GO:0080184)3.37103348
146cholesterol efflux (GO:0033344)3.36534922
147metanephric epithelium development (GO:0072207)3.30450061
148nephron tubule formation (GO:0072079)3.17209118

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1* RXR_22158963_ChIP-Seq_LIVER_Mouse7.98352011
2* PPARA_22158963_ChIP-Seq_LIVER_Mouse6.83615881
3LXR_22158963_ChIP-Seq_LIVER_Mouse6.13339962
4EGR1_23403033_ChIP-Seq_LIVER_Mouse5.97151919
5PPARG_19300518_ChIP-PET_3T3-L1_Mouse4.87945622
6FOXO1_23066095_ChIP-Seq_LIVER_Mouse4.55243033
7CEBPA_23403033_ChIP-Seq_LIVER_Mouse4.07566450
8NR1I2_20693526_ChIP-Seq_LIVER_Mouse3.76384103
9CEBPB_23403033_ChIP-Seq_LIVER_Mouse3.54204446
10TP63_17297297_ChIP-ChIP_HaCaT_Human2.73080975
11HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.44317877
12TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.39128284
13TCF7L2_21901280_ChIP-Seq_H4IIE_Rat2.17403925
14ESR1_20079471_ChIP-ChIP_T-47D_Human2.09637106
15ESR1_17901129_ChIP-ChIP_LIVER_Mouse11.0346787
16BP1_19119308_ChIP-ChIP_Hs578T_Human1.89581432
17CLOCK_20551151_ChIP-Seq_293T_Human1.76647881
18HIF1A_21447827_ChIP-Seq_MCF-7_Human1.74512351
19FOXA2_19822575_ChIP-Seq_HepG2_Human1.67982363
20* HNF4A_19822575_ChIP-Seq_HepG2_Human1.58898707
21ESR1_21235772_ChIP-Seq_MCF-7_Human1.53044668
22ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.43110907
23RARG_19884340_ChIP-ChIP_MEFs_Mouse1.42590533
24STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.38515799
25MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.37171670
26ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.29316840
27TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.27848771
28PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.27624768
29ESR2_21235772_ChIP-Seq_MCF-7_Human1.20696546
30SOX2_27498859_Chip-Seq_STOMACH_Mouse1.19671034
31TP53_18474530_ChIP-ChIP_U2OS_Human1.18248781
32IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.15912739
33GATA4_25053715_ChIP-Seq_YYC3_Human1.09030752
34GATA1_22025678_ChIP-Seq_K562_Human1.04721032
35CDX2_20551321_ChIP-Seq_CACO-2_Human1.03746346
36* RXRA_24833708_ChIP-Seq_LIVER_Mouse1.00441664
37GATA2_21666600_ChIP-Seq_HMVEC_Human0.97569778
38NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.97414681
39CJUN_26792858_Chip-Seq_BT549_Human0.92384745
40THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.91852183
41HTT_18923047_ChIP-ChIP_STHdh_Human0.90431165
42PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.90219083
43RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.88840821
44CDX2_19796622_ChIP-Seq_MESCs_Mouse0.84852456
45EGR1_19032775_ChIP-ChIP_M12_Human0.84648599
46BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.83940800
47AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.83710087
48STAT3_1855785_ChIP-Seq_MESCs_Mouse0.83426711
49TP53_16413492_ChIP-PET_HCT116_Human0.83208375
50LXR_22292898_ChIP-Seq_THP-1_Human0.83006466
51NFE2_27457419_Chip-Seq_LIVER_Mouse0.82828128
52NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.82468479
53E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.78707187
54IRF8_22096565_ChIP-ChIP_GC-B_Human0.78540771
55CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.77485938
56Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.75729231
57AR_21909140_ChIP-Seq_LNCAP_Human0.75721832
58AUTS2_25519132_ChIP-Seq_293T-REX_Human0.75381756
59PCGF2_27294783_Chip-Seq_NPCs_Mouse0.75023332
60SMAD4_19686287_ChIP-ChIP_HaCaT_Human0.74627098
61STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.73788114
62SALL4_18804426_ChIP-ChIP_XEN_Mouse0.73570730
63GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.73063715
64FOXO3_23340844_ChIP-Seq_DLD1_Human0.73005136
65KAP1_22055183_ChIP-Seq_ESCs_Mouse0.72722328
66TCF4_18268006_ChIP-ChIP_LS174T_Human0.72116850
67BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.71735110
68RAD21_21589869_ChIP-Seq_MESCs_Mouse0.71577458
69CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.71163325
70NRF2_20460467_ChIP-Seq_MEFs_Mouse0.70900498
71NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.70900498
72TRIM28_21343339_ChIP-Seq_HEK293_Human0.70800421
73SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.69588138
74CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.69377821
75DROSHA_22980978_ChIP-Seq_HELA_Human0.68946129
76NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.68272597
77GATA6_25053715_ChIP-Seq_YYC3_Human0.67836855
78MYC_19915707_ChIP-ChIP_AK7_Human0.67284718
79ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.67192791
80HNFA_21074721_ChIP-Seq_CACO-2_Human0.66447654
81NFYA_21822215_ChIP-Seq_K562_Human0.66314151
82SUZ12_27294783_Chip-Seq_NPCs_Mouse0.65329421
83SOX2_21211035_ChIP-Seq_LN229_Human0.64057819
84CEBPB_22108803_ChIP-Seq_LS180_Human0.63545585
85FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.63161136
86ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.62618525
87SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.62498538
88EZH2_27294783_Chip-Seq_NPCs_Mouse0.62464743
89CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.62389178
90SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.60894891
91AR_20517297_ChIP-Seq_VCAP_Human0.60582724
92OCT4_21477851_ChIP-Seq_ESCs_Mouse0.59427509
93TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.58390081
94FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.58288488
95PPAR_26484153_Chip-Seq_NCI-H1993_Human0.57867052
96P53_21459846_ChIP-Seq_SAOS-2_Human0.57728987
97CRX_20693478_ChIP-Seq_RETINA_Mouse0.57624556
98CTCF_27219007_Chip-Seq_Bcells_Human0.57217477
99ESET_19884257_ChIP-Seq_ESCs_Mouse0.57162378
100EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.56972046
101SMC4_20622854_ChIP-Seq_HELA_Human0.56842861
102RARA_24833708_ChIP-Seq_LIVER_Mouse0.56825189
103RACK7_27058665_Chip-Seq_MCF-7_Human0.56753288
104ZNF217_24962896_ChIP-Seq_MCF-7_Human0.55870349
105TAF2_19829295_ChIP-Seq_ESCs_Human0.55591832
106CBP_21632823_ChIP-Seq_H3396_Human0.55432554
107ETV2_25802403_ChIP-Seq_MESCs_Mouse0.55206398
108ZNF263_19887448_ChIP-Seq_K562_Human0.54814897
109GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.54782406
110STAT1_17558387_ChIP-Seq_HELA_Human0.54626435
111SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.54614843
112PHF8_20622853_ChIP-Seq_HELA_Human0.54417434
113MTF2_20144788_ChIP-Seq_MESCs_Mouse0.54212131
114SRY_22984422_ChIP-ChIP_TESTIS_Rat0.54032967
115JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.53676771
116FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.53443091
117ERG_21242973_ChIP-ChIP_JURKAT_Human0.52018276
118TBX20_22328084_ChIP-Seq_HEART_Mouse0.51329421
119TBX20_22080862_ChIP-Seq_HEART_Mouse0.51329421
120SOX2_20726797_ChIP-Seq_SW620_Human0.50646409
121ESR1_15608294_ChIP-ChIP_MCF-7_Human0.50637146
122GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.50619798
123FOXA1_25552417_ChIP-Seq_VCAP_Human0.50351887
124GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.50244722
125FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.49947454
126ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.49392879
127P63_20808887_ChIP-Seq_KERATINOCYTES_Human0.49023779
128PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.48937799
129SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.48913919
130* CDX2_22108803_ChIP-Seq_LS180_Human0.48891137
131GATA2_19941826_ChIP-Seq_K562_Human0.48463505
132PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.47281543
133PIAS1_25552417_ChIP-Seq_VCAP_Human0.46728347
134RARB_24833708_ChIP-Seq_LIVER_Mouse0.46348119
135CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.46150295
136PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.45363426
137EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.45113116
138RAC3_21632823_ChIP-Seq_H3396_Human0.44093420
139FOXH1_21741376_ChIP-Seq_EPCs_Human0.43909427

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005360_urolithiasis8.46847617
2MP0002139_abnormal_hepatobiliary_system7.67841355
3MP0005085_abnormal_gallbladder_physiolo5.34299864
4MP0005365_abnormal_bile_salt5.16739536
5MP0008875_abnormal_xenobiotic_pharmacok4.70409442
6MP0005332_abnormal_amino_acid4.00515815
7MP0003252_abnormal_bile_duct3.76678574
8MP0003195_calcinosis3.70464962
9MP0004019_abnormal_vitamin_homeostasis3.59816770
10MP0003806_abnormal_nucleotide_metabolis3.52405684
11MP0002138_abnormal_hepatobiliary_system3.06593433
12MP0004043_abnormal_pH_regulation2.83727401
13MP0010329_abnormal_lipoprotein_level2.69047246
14MP0009643_abnormal_urine_homeostasis2.52188138
15MP0005083_abnormal_biliary_tract2.18751589
16MP0001666_abnormal_nutrient_absorption2.18718352
17MP0009840_abnormal_foam_cell2.01707478
18MP0005636_abnormal_mineral_homeostasis1.97586111
19MP0003191_abnormal_cellular_cholesterol1.91604694
20MP0005319_abnormal_enzyme/_coenzyme1.82992048
21MP0002118_abnormal_lipid_homeostasis1.79476702
22MP0005584_abnormal_enzyme/coenzyme_acti1.75202955
23MP0000609_abnormal_liver_physiology1.73301091
24MP0001765_abnormal_ion_homeostasis1.72599427
25MP0001756_abnormal_urination1.69606502
26MP0003186_abnormal_redox_activity1.60864188
27MP0001764_abnormal_homeostasis1.58556006
28MP0002136_abnormal_kidney_physiology1.55761865
29MP0005451_abnormal_body_composition1.45058523
30MP0003868_abnormal_feces_composition1.23213459
31MP0005084_abnormal_gallbladder_morpholo1.20253089
32MP0002876_abnormal_thyroid_physiology1.13001153
33MP0004272_abnormal_basement_membrane1.10232093
34MP0010386_abnormal_urinary_bladder1.09436907
35MP0006036_abnormal_mitochondrial_physio1.09190767
36MP0003879_abnormal_hair_cell1.08241671
37MP0005058_abnormal_lysosome_morphology1.03201551
38MP0000598_abnormal_liver_morphology1.01569970
39MP0009764_decreased_sensitivity_to0.98286006
40MP0005670_abnormal_white_adipose0.95520458
41MP0002928_abnormal_bile_duct0.93787656
42MP0005535_abnormal_body_temperature0.92902230
43MP0009642_abnormal_blood_homeostasis0.90715857
44MP0001661_extended_life_span0.83745542
45MP0008469_abnormal_protein_level0.83632400
46MP0005220_abnormal_exocrine_pancreas0.82077299
47MP0005647_abnormal_sex_gland0.80527897
48MP0003705_abnormal_hypodermis_morpholog0.80405967
49MP0005377_hearing/vestibular/ear_phenot0.79973105
50MP0003878_abnormal_ear_physiology0.79973105
51MP0000538_abnormal_urinary_bladder0.79111082
52MP0005408_hypopigmentation0.77178068
53MP0003011_delayed_dark_adaptation0.77086100
54MP0000604_amyloidosis0.76967586
55MP0001958_emphysema0.75779915
56MP0008961_abnormal_basal_metabolism0.75386603
57MP0002132_abnormal_respiratory_system0.74749969
58MP0001915_intracranial_hemorrhage0.74734094
59MP0002168_other_aberrant_phenotype0.72551348
60MP0002078_abnormal_glucose_homeostasis0.71906987
61MP0000230_abnormal_systemic_arterial0.70450454
62MP0009763_increased_sensitivity_to0.70304795
63MP0003656_abnormal_erythrocyte_physiolo0.69771671
64MP0003638_abnormal_response/metabolism_0.66371176
65MP0005376_homeostasis/metabolism_phenot0.63441811
66MP0003183_abnormal_peptide_metabolism0.63291013
67MP0005666_abnormal_adipose_tissue0.62880831
68MP0003300_gastrointestinal_ulcer0.61904688
69MP0006035_abnormal_mitochondrial_morpho0.61772780
70MP0009765_abnormal_xenobiotic_induced0.61207938
71MP0003329_amyloid_beta_deposits0.61120184
72MP0002135_abnormal_kidney_morphology0.61060996
73MP0009697_abnormal_copulation0.60168248
74MP0005395_other_phenotype0.59799712
75MP0000534_abnormal_ureter_morphology0.59398617
76MP0002971_abnormal_brown_adipose0.58601127
77MP0005464_abnormal_platelet_physiology0.57962329
78MP0004264_abnormal_extraembryonic_tissu0.53640174
79MP0004885_abnormal_endolymph0.52989358
80MP0004147_increased_porphyrin_level0.50800345
81MP0005187_abnormal_penis_morphology0.50450347
82MP0000249_abnormal_blood_vessel0.50119075
83MP0002796_impaired_skin_barrier0.49974892
84MP0005334_abnormal_fat_pad0.49336210
85MP0005266_abnormal_metabolism0.48458035
86MP0000013_abnormal_adipose_tissue0.46795401
87MP0003690_abnormal_glial_cell0.46414897
88MP0003953_abnormal_hormone_level0.46122114
89MP0002254_reproductive_system_inflammat0.45352710
90MP0002089_abnormal_postnatal_growth/wei0.44338295
91MP0003724_increased_susceptibility_to0.43265083
92MP0004130_abnormal_muscle_cell0.42463575
93MP0005197_abnormal_uvea_morphology0.41888641
94MP0005023_abnormal_wound_healing0.41055770
95MP0010368_abnormal_lymphatic_system0.40703453
96MP0000003_abnormal_adipose_tissue0.40562851
97MP0009785_altered_susceptibility_to0.39877612
98MP0010234_abnormal_vibrissa_follicle0.39835301
99MP0003959_abnormal_lean_body0.39609214
100MP0000467_abnormal_esophagus_morphology0.39225888
101MP0008775_abnormal_heart_ventricle0.39067152
102MP0009672_abnormal_birth_weight0.38431316
103MP0009053_abnormal_anal_canal0.37558865
104MP0002896_abnormal_bone_mineralization0.36598626
105MP0003566_abnormal_cell_adhesion0.36397375
106MP0003283_abnormal_digestive_organ0.36343876
107MP0005166_decreased_susceptibility_to0.36092712
108MP0000678_abnormal_parathyroid_gland0.36003689
109MP0008874_decreased_physiological_sensi0.35258845
110MP0001944_abnormal_pancreas_morphology0.34098832
111MP0003075_altered_response_to0.33328346
112MP0003045_fibrosis0.32882083
113MP0003172_abnormal_lysosome_physiology0.31273419
114MP0000920_abnormal_myelination0.31065948
115MP0004510_myositis0.30383676
116MP0008872_abnormal_physiological_respon0.30239689
117MP0002249_abnormal_larynx_morphology0.30193386
118MP0002090_abnormal_vision0.29481349
119MP0008873_increased_physiological_sensi0.29339196
120MP0002909_abnormal_adrenal_gland0.29141754
121MP0002269_muscular_atrophy0.28392650
122MP0002837_dystrophic_cardiac_calcinosis0.28094182
123MP0001845_abnormal_inflammatory_respons0.27878959
124MP0005164_abnormal_response_to0.27075859
125MP0001324_abnormal_eye_pigmentation0.26991671
126MP0009384_cardiac_valve_regurgitation0.26849197
127MP0000371_diluted_coat_color0.25356363
128MP0005448_abnormal_energy_balance0.24919572
129MP0002069_abnormal_eating/drinking_beha0.24722455
130MP0004782_abnormal_surfactant_physiolog0.24171133
131MP0005167_abnormal_blood-brain_barrier0.23972922

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of aromatic amino acid family metabolism (HP:0004338)5.76606653
2Gout (HP:0001997)5.65174711
3Intrahepatic cholestasis (HP:0001406)5.29651259
4Abnormality of glutamine family amino acid metabolism (HP:0010902)5.24627217
5Hyperglycinuria (HP:0003108)5.18085368
6Glomerulonephritis (HP:0000099)4.80032516
7Abnormality of glycine metabolism (HP:0010895)4.72492969
8Abnormality of serine family amino acid metabolism (HP:0010894)4.72492969
9Xanthomatosis (HP:0000991)4.64738789
10Abnormality of monocarboxylic acid metabolism (HP:0010996)4.64027451
11Potter facies (HP:0002009)4.61463063
12Facial shape deformation (HP:0011334)4.61463063
13Ketosis (HP:0001946)4.57160695
14Deep venous thrombosis (HP:0002625)4.53880810
15Hyperglycinemia (HP:0002154)4.40885316
16Increased circulating renin level (HP:0000848)4.34951085
17Abnormality of purine metabolism (HP:0004352)4.32318948
18Hypokalemic alkalosis (HP:0001949)4.27498310
19Proximal tubulopathy (HP:0000114)4.24481164
20Hyperammonemia (HP:0001987)4.20496012
21Abnormality of aspartate family amino acid metabolism (HP:0010899)4.16784835
22Ketoacidosis (HP:0001993)4.14297411
23Increased purine levels (HP:0004368)4.02731786
24Hyperuricemia (HP:0002149)4.02731786
25Metabolic alkalosis (HP:0200114)4.01625613
26Hyperactive renin-angiotensin system (HP:0000841)3.97517498
27Alkalosis (HP:0001948)3.85710597
28Abnormality of sulfur amino acid metabolism (HP:0004339)3.84619465
29Abnormality of nucleobase metabolism (HP:0010932)3.83105412
30Hypomagnesemia (HP:0002917)3.80459355
31Nephritis (HP:0000123)3.75737939
32Prolonged partial thromboplastin time (HP:0003645)3.73725776
33Abnormality of fatty-acid metabolism (HP:0004359)3.71213734
34Hypobetalipoproteinemia (HP:0003563)3.68617399
35Polyuria (HP:0000103)3.63211475
36Generalized aminoaciduria (HP:0002909)3.62918516
37Abnormal urine output (HP:0012590)3.60978654
38Delayed CNS myelination (HP:0002188)3.57471884
39Abnormality of chloride homeostasis (HP:0011422)3.52600764
40Recurrent gram-negative bacterial infections (HP:0005420)3.43864390
41Abnormality of renal excretion (HP:0011036)3.39028394
42Complement deficiency (HP:0004431)3.33024092
43Hyperlipoproteinemia (HP:0010980)3.32424736
44Vascular calcification (HP:0004934)3.19688921
45Joint hemorrhage (HP:0005261)3.18843108
46Abnormality of magnesium homeostasis (HP:0004921)3.16231771
47Hypoglycemic coma (HP:0001325)3.15598873
48Abnormality of urine glucose concentration (HP:0011016)3.12371365
49Glycosuria (HP:0003076)3.12371365
50Focal segmental glomerulosclerosis (HP:0000097)3.11336762
51Metabolic acidosis (HP:0001942)3.05364266
52Fat malabsorption (HP:0002630)3.02804370
53Abnormality of dicarboxylic acid metabolism (HP:0010995)2.97035572
54Dicarboxylic aciduria (HP:0003215)2.97035572
55Abnormality of serum amino acid levels (HP:0003112)2.91284721
56Spontaneous abortion (HP:0005268)2.89110483
57Epidermoid cyst (HP:0200040)2.88074734
58Abnormality of pyrimidine metabolism (HP:0004353)2.84678341
59Cardiovascular calcification (HP:0011915)2.83936336
60Abnormality of methionine metabolism (HP:0010901)2.81652956
61Polydipsia (HP:0001959)2.80720403
62Abnormal drinking behavior (HP:0030082)2.80720403
63Osteomalacia (HP:0002749)2.80215997
64Abnormality of proline metabolism (HP:0010907)2.79675171
65Hydroxyprolinuria (HP:0003080)2.79675171
66Lethargy (HP:0001254)2.78481064
67Hypolipoproteinemia (HP:0010981)2.74820119
68Abnormality of the common coagulation pathway (HP:0010990)2.74549445
69Hemorrhage of the eye (HP:0011885)2.68836586
70Rickets (HP:0002748)2.68531189
71Mitral stenosis (HP:0001718)2.65752393
72Malnutrition (HP:0004395)2.65518332
73Menorrhagia (HP:0000132)2.64574932
74Enlarged kidneys (HP:0000105)2.63870884
75Conjugated hyperbilirubinemia (HP:0002908)2.63810901
76Tetany (HP:0001281)2.63790508
77Hepatocellular carcinoma (HP:0001402)2.60456814
78Renal salt wasting (HP:0000127)2.60443551
79Vomiting (HP:0002013)2.59810068
80Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.59247006
81Purpura (HP:0000979)2.58894594
82Reduced antithrombin III activity (HP:0001976)2.58805363
83Glomerulosclerosis (HP:0000096)2.58219423
84Abnormality of renin-angiotensin system (HP:0000847)2.58183564
85Renal tubular acidosis (HP:0001947)2.55838965
86Nephrolithiasis (HP:0000787)2.55588543
87Hyperaldosteronism (HP:0000859)2.53340620
88Hyperphosphaturia (HP:0003109)2.53126105
89Hyperbilirubinemia (HP:0002904)2.52944448
90Abnormality of the level of lipoprotein cholesterol (HP:0010979)2.49721656
91Gingival bleeding (HP:0000225)2.48644374
92Irritability (HP:0000737)2.42926860
93Hypoalphalipoproteinemia (HP:0003233)2.41246466
94Abnormal enzyme/coenzyme activity (HP:0012379)2.41194825
95Neonatal onset (HP:0003623)2.40683231
96Sensorimotor neuropathy (HP:0007141)2.37138655
97Spastic diplegia (HP:0001264)2.34651781
98Abnormality of complement system (HP:0005339)2.31471105
99Abnormal urine phosphate concentration (HP:0012599)2.27482450
100Abnormality of the intrinsic pathway (HP:0010989)2.25255711
101Hypophosphatemia (HP:0002148)2.24165254
102Steatorrhea (HP:0002570)2.22763045
103Late onset (HP:0003584)2.22556293
104Abnormality of alkaline phosphatase activity (HP:0004379)2.22175392
105Cerebral edema (HP:0002181)2.22150983
106Confusion (HP:0001289)2.21859537
107Chorioretinal atrophy (HP:0000533)2.16436681
108Pulmonary embolism (HP:0002204)2.13998490
109Hypercalciuria (HP:0002150)2.11182743
110Arthropathy (HP:0003040)2.09607723
111Hypercholesterolemia (HP:0003124)2.08207087
112Abnormal platelet function (HP:0011869)2.06131794
113Impaired platelet aggregation (HP:0003540)2.06131794
114Hypophosphatemic rickets (HP:0004912)2.06092741
115Abnormal gallbladder physiology (HP:0012438)2.04027953
116Cholecystitis (HP:0001082)2.04027953
117Thrombophlebitis (HP:0004418)2.01483041
118Elevated alkaline phosphatase (HP:0003155)2.01352466
119Pancreatitis (HP:0001733)1.99865169
120Increased mean platelet volume (HP:0011877)1.99133154
121Systemic lupus erythematosus (HP:0002725)1.98125230
122Nephrocalcinosis (HP:0000121)1.96138605
123Nausea (HP:0002018)1.95940519
124Abnormality of macular pigmentation (HP:0008002)1.93700265
125Methylmalonic aciduria (HP:0012120)1.92239204
126Hypokalemia (HP:0002900)1.92045677
127Fair hair (HP:0002286)1.90040438

Predicted kinase interactions (KEA)

RankGene SetZ-score
1WNK46.58148447
2WNK36.19196287
3BCKDK5.83216615
4OXSR15.46857673
5FGFR43.12727060
6STK392.91741983
7ERN12.64206991
8STK38L2.40381473
9SIK12.31774991
10PIK3CA2.26612079
11MST1R2.01152148
12INSRR1.79333165
13ERBB41.76695453
14PDK31.64583796
15PDK41.64583796
16NTRK11.58351984
17SGK2231.54754884
18SGK4941.54754884
19EPHA21.51515604
20BLK1.45808825
21NEK11.44947206
22MAPK111.36390189
23TAOK31.32343862
24PINK11.24741279
25MAP2K41.23612246
26PDGFRA1.15732856
27MAP3K71.12951178
28GRK61.12521875
29SGK31.11051752
30ABL21.10031682
31TRIB31.06551150
32WNK11.05672507
33PDK21.05233102
34SGK21.04680207
35STK381.03737768
36PTK61.03651378
37LATS11.01436692
38TTN1.00215745
39EPHB10.95306920
40PIK3CG0.92444218
41FRK0.87861764
42GSK3A0.87674128
43PRKAA20.85662567
44PKN20.85077668
45KIT0.84857983
46MAP3K30.80585289
47TIE10.80548630
48FGFR30.80201310
49TYK20.80022601
50DYRK1B0.78736081
51MOS0.76680951
52TRPM70.75540840
53DAPK20.75469481
54NEK90.74586789
55JAK20.74504964
56PRKAA10.73842085
57MAP3K140.71552523
58PRKCZ0.70705528
59CAMKK20.69554026
60MET0.68399552
61PTK20.68209989
62PRPF4B0.66026218
63MAPK150.64501410
64PAK20.63465214
65TGFBR20.62960293
66EPHB20.62433923
67MAP2K30.61889925
68ZAP700.61687378
69PRKD20.61016047
70LRRK20.59996438
71SRC0.59849449
72FLT30.59820252
73KDR0.59817112
74EPHA30.58451083
75PDPK10.57114022
76CSF1R0.55414104
77FGFR20.55192065
78PRKCE0.53390417
79PRKACG0.51432503
80ERBB20.51220832
81IRAK30.48414562
82NTRK30.47253304
83MAPK40.46985560
84CDK90.46256654
85INSR0.46230322
86RIPK10.46064624
87JAK30.45050315
88MAPK120.44260753
89MAP3K90.43763210
90ICK0.42954619
91JAK10.40180435
92PRKG10.39159128
93TBK10.38555503
94MAP3K110.38220272
95SGK10.37199994
96PAK30.36130261
97PDK10.35552733
98MAP3K130.35523295
99RPS6KA30.35344037
100CDC42BPA0.34573846
101CSK0.34207993
102PRKCB0.33205803
103MAP3K100.32778307
104IRAK20.32084386
105MAPKAPK30.31002170
106EPHA40.30777801
107DDR20.30501549
108MAP2K60.30186056
109CAMK2G0.29855710
110RPS6KA20.28244494
111PRKCQ0.27226060
112PRKACB0.25916677
113CDK60.23453582
114PRKCG0.23363712
115IGF1R0.22644627
116PRKCA0.22282642
117CSNK1G10.21474999
118IRAK10.21376510
119FER0.21302497
120PRKCD0.20473751
121MTOR0.20396374
122BMX0.19085417
123GRK10.18597293
124MAP3K20.16851251
125MYLK0.15793266
126PRKCH0.15020242
127PRKACA0.14808686
128CAMK40.14760969
129EGFR0.13563383
130CAMK1G0.13221375
131MAPK70.13055899
132AKT20.12602622
133MAP3K60.12401703
134CAMK1D0.12358967
135STK110.12309617

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001203.62812312
2Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.49297484
3Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006303.06042348
4Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.03113105
5Butanoate metabolism_Homo sapiens_hsa006503.01167771
6Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.88075012
7Nitrogen metabolism_Homo sapiens_hsa009102.81092132
8Tryptophan metabolism_Homo sapiens_hsa003802.73428907
9Pentose and glucuronate interconversions_Homo sapiens_hsa000402.61827848
10Fatty acid degradation_Homo sapiens_hsa000712.59480710
11Propanoate metabolism_Homo sapiens_hsa006402.53769189
12Arginine biosynthesis_Homo sapiens_hsa002202.53183198
13Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.52964310
14Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.51638775
15Peroxisome_Homo sapiens_hsa041462.42778735
16Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.41161898
17Cyanoamino acid metabolism_Homo sapiens_hsa004602.17240253
182-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.09661009
19beta-Alanine metabolism_Homo sapiens_hsa004101.91571180
20Fatty acid metabolism_Homo sapiens_hsa012121.89860153
21Pyruvate metabolism_Homo sapiens_hsa006201.86891723
22Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.85391144
23Complement and coagulation cascades_Homo sapiens_hsa046101.84034049
24Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.78173574
25PPAR signaling pathway_Homo sapiens_hsa033201.73526182
26Histidine metabolism_Homo sapiens_hsa003401.70932808
27Bile secretion_Homo sapiens_hsa049761.65656944
28Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.59363713
29Sulfur metabolism_Homo sapiens_hsa009201.57778172
30Steroid hormone biosynthesis_Homo sapiens_hsa001401.56625650
31Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.55057296
32Selenocompound metabolism_Homo sapiens_hsa004501.54369737
33Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.52550611
34Chemical carcinogenesis_Homo sapiens_hsa052041.52377923
35Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.47881625
36Phenylalanine metabolism_Homo sapiens_hsa003601.42199886
37Drug metabolism - other enzymes_Homo sapiens_hsa009831.41812914
38Carbon metabolism_Homo sapiens_hsa012001.39925519
39Vitamin digestion and absorption_Homo sapiens_hsa049771.36740461
40Retinol metabolism_Homo sapiens_hsa008301.31592525
41Starch and sucrose metabolism_Homo sapiens_hsa005001.29114871
42Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.27003766
43Arginine and proline metabolism_Homo sapiens_hsa003301.20005665
44Biosynthesis of amino acids_Homo sapiens_hsa012301.18850879
45Cysteine and methionine metabolism_Homo sapiens_hsa002701.18532746
46Folate biosynthesis_Homo sapiens_hsa007901.16018574
47Fatty acid elongation_Homo sapiens_hsa000621.14096111
48Tyrosine metabolism_Homo sapiens_hsa003501.11549907
49Lysine degradation_Homo sapiens_hsa003101.07915464
50Caffeine metabolism_Homo sapiens_hsa002321.06138017
51Glutathione metabolism_Homo sapiens_hsa004801.05105993
52Staphylococcus aureus infection_Homo sapiens_hsa051501.03283012
53Maturity onset diabetes of the young_Homo sapiens_hsa049500.94224237
54Steroid biosynthesis_Homo sapiens_hsa001000.92501414
55Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.92152898
56ABC transporters_Homo sapiens_hsa020100.91027971
57Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.89666060
58Glycerolipid metabolism_Homo sapiens_hsa005610.80831189
59Sulfur relay system_Homo sapiens_hsa041220.75340296
60Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.71505108
61Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.70328485
62Fat digestion and absorption_Homo sapiens_hsa049750.66704924
63Pentose phosphate pathway_Homo sapiens_hsa000300.60014098
64Vitamin B6 metabolism_Homo sapiens_hsa007500.56640178
65Metabolic pathways_Homo sapiens_hsa011000.52661868
66One carbon pool by folate_Homo sapiens_hsa006700.51648178
67Fructose and mannose metabolism_Homo sapiens_hsa000510.47323315
68Collecting duct acid secretion_Homo sapiens_hsa049660.36244976
69Sphingolipid metabolism_Homo sapiens_hsa006000.35166496
70Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.26995441
71Protein digestion and absorption_Homo sapiens_hsa049740.26991190
72Other glycan degradation_Homo sapiens_hsa005110.24785648
73Pertussis_Homo sapiens_hsa051330.23784506
74Mineral absorption_Homo sapiens_hsa049780.23664429
75Galactose metabolism_Homo sapiens_hsa000520.19776696
76Insulin resistance_Homo sapiens_hsa049310.18315329
77Adipocytokine signaling pathway_Homo sapiens_hsa049200.16855809
78alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.16121934
79Fatty acid biosynthesis_Homo sapiens_hsa000610.14228744
80Renin-angiotensin system_Homo sapiens_hsa046140.13816902
81Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.13652319
82Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.12440673
83Glycosaminoglycan degradation_Homo sapiens_hsa005310.12017452
84African trypanosomiasis_Homo sapiens_hsa051430.11222400
85ECM-receptor interaction_Homo sapiens_hsa045120.10497535
86Carbohydrate digestion and absorption_Homo sapiens_hsa049730.08467326
87Prion diseases_Homo sapiens_hsa050200.05806469
88Thyroid hormone synthesis_Homo sapiens_hsa049180.05438042
89Glucagon signaling pathway_Homo sapiens_hsa049220.04377484
90Lysosome_Homo sapiens_hsa041420.03984790
91Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.03779049
92Ether lipid metabolism_Homo sapiens_hsa005650.03478589
93Amoebiasis_Homo sapiens_hsa051460.02868996
94Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.01184846
95AMPK signaling pathway_Homo sapiens_hsa041520.00810513
96Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.00388715
97Arachidonic acid metabolism_Homo sapiens_hsa005900.00334675
98Insulin signaling pathway_Homo sapiens_hsa04910-0.1836474
99Bladder cancer_Homo sapiens_hsa05219-0.1808761
100Ovarian steroidogenesis_Homo sapiens_hsa04913-0.1712102
101Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520-0.1609975
102Hepatitis C_Homo sapiens_hsa05160-0.1513884
103Circadian rhythm_Homo sapiens_hsa04710-0.1407292
104Regulation of autophagy_Homo sapiens_hsa04140-0.1333515
105Central carbon metabolism in cancer_Homo sapiens_hsa05230-0.1308181
106Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604-0.1243222
107Choline metabolism in cancer_Homo sapiens_hsa05231-0.1162548
108N-Glycan biosynthesis_Homo sapiens_hsa00510-0.0756145
109Linoleic acid metabolism_Homo sapiens_hsa00591-0.0599729
110Oxidative phosphorylation_Homo sapiens_hsa00190-0.0481031
111Serotonergic synapse_Homo sapiens_hsa04726-0.0456224
112Glycerophospholipid metabolism_Homo sapiens_hsa00564-0.0049885
113Systemic lupus erythematosus_Homo sapiens_hsa05322-0.0025667

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