SLC17A4

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Phosphate homeostasis is maintained by regulating intake, intestinal absorption, bone deposition and resorption, and renal excretion of phosphate. The central molecule in the control of phosphate excretion from the kidney is the sodium/phosphate cotransporter NPT1 (SLC17A1; MIM 182308), which is located in the renal proximal tubule. NPT1 uses the transmembrane electrochemical potential gradient of sodium to transport phosphate across the cell membrane. SLC17A4 is a similar sodium/phosphate cotransporter in the intestinal mucosa that plays an important role in the absorption of phosphate from the intestine (summary by Shibui et al., 1999 [PubMed 10319585]). NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1epoxygenase P450 pathway (GO:0019373)8.41571462
2L-phenylalanine catabolic process (GO:0006559)7.30725628
3erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)7.30725628
4exogenous drug catabolic process (GO:0042738)7.23272024
5L-phenylalanine metabolic process (GO:0006558)7.00573553
6erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)7.00573553
7aromatic amino acid family catabolic process (GO:0009074)6.55953341
8triglyceride-rich lipoprotein particle remodeling (GO:0034370)6.51938254
9omega-hydroxylase P450 pathway (GO:0097267)6.28590726
10drug metabolic process (GO:0017144)6.24502412
11indole-containing compound catabolic process (GO:0042436)5.91820419
12indolalkylamine catabolic process (GO:0046218)5.91820419
13tryptophan catabolic process (GO:0006569)5.91820419
14kynurenine metabolic process (GO:0070189)5.79624661
15bile acid biosynthetic process (GO:0006699)5.69324446
16alpha-linolenic acid metabolic process (GO:0036109)5.68822637
17high-density lipoprotein particle remodeling (GO:0034375)5.61342532
18tryptophan metabolic process (GO:0006568)5.59359380
19glyoxylate metabolic process (GO:0046487)5.50500137
20urea metabolic process (GO:0019627)5.50455237
21urea cycle (GO:0000050)5.50455237
22negative regulation of fibrinolysis (GO:0051918)5.37825773
23sulfur amino acid catabolic process (GO:0000098)5.35143641
24regulation of fibrinolysis (GO:0051917)5.17650464
25cysteine metabolic process (GO:0006534)5.16737882
26protein carboxylation (GO:0018214)5.16638892
27peptidyl-glutamic acid carboxylation (GO:0017187)5.16638892
28alkaloid metabolic process (GO:0009820)5.07150243
29regulation of cholesterol esterification (GO:0010872)5.06276487
30nitrogen cycle metabolic process (GO:0071941)5.05158069
31regulation of protein activation cascade (GO:2000257)5.04000591
32bile acid metabolic process (GO:0008206)5.03655855
33complement activation, alternative pathway (GO:0006957)5.01274971
34oxidative demethylation (GO:0070989)4.98913617
35fat-soluble vitamin biosynthetic process (GO:0042362)4.98763979
36negative regulation of sterol transport (GO:0032372)4.96233794
37negative regulation of cholesterol transport (GO:0032375)4.96233794
38phenylpropanoid metabolic process (GO:0009698)4.95554151
39serine family amino acid catabolic process (GO:0009071)4.95350479
40phospholipid efflux (GO:0033700)4.90202380
41reverse cholesterol transport (GO:0043691)4.90104136
42regulation of triglyceride catabolic process (GO:0010896)4.89942747
43plasma lipoprotein particle remodeling (GO:0034369)4.82362816
44protein-lipid complex remodeling (GO:0034368)4.82362816
45macromolecular complex remodeling (GO:0034367)4.82362816
46bile acid and bile salt transport (GO:0015721)4.80346514
47fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)4.80189250
48hormone catabolic process (GO:0042447)4.80163274
49aromatic amino acid family metabolic process (GO:0009072)4.78147053
50homocysteine metabolic process (GO:0050667)4.69771455
51cellular ketone body metabolic process (GO:0046950)4.68164691
52regulation of complement activation (GO:0030449)4.67108147
53acylglycerol homeostasis (GO:0055090)4.65357357
54triglyceride homeostasis (GO:0070328)4.65357357
55tyrosine metabolic process (GO:0006570)4.60839145
56ethanol metabolic process (GO:0006067)4.56730513
57angiotensin maturation (GO:0002003)4.53811034
58amino-acid betaine metabolic process (GO:0006577)4.51936325
59regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)4.50183039
60cellular glucuronidation (GO:0052695)4.44871618
61intestinal absorption (GO:0050892)4.43808080
62alpha-amino acid catabolic process (GO:1901606)4.43615997
63lysine catabolic process (GO:0006554)4.40275829
64lysine metabolic process (GO:0006553)4.40275829
65plasma lipoprotein particle clearance (GO:0034381)4.39366239
66cholesterol efflux (GO:0033344)4.33890333
67negative regulation of hemostasis (GO:1900047)4.33874726
68negative regulation of blood coagulation (GO:0030195)4.33874726
69imidazole-containing compound metabolic process (GO:0052803)4.21275489
70indolalkylamine metabolic process (GO:0006586)4.21031827
71plasma lipoprotein particle assembly (GO:0034377)4.20436349
72glycine metabolic process (GO:0006544)4.20129509
73ethanol oxidation (GO:0006069)4.13136240
74drug catabolic process (GO:0042737)4.13108100
75coenzyme catabolic process (GO:0009109)4.12964193
76negative regulation of coagulation (GO:0050819)4.10616794
77cellular amino acid catabolic process (GO:0009063)4.10449807
78benzene-containing compound metabolic process (GO:0042537)4.09465304
79cellular biogenic amine catabolic process (GO:0042402)4.07740186
80amine catabolic process (GO:0009310)4.07740186
81glutamate metabolic process (GO:0006536)4.06067227
82very-low-density lipoprotein particle assembly (GO:0034379)4.06065956
83ketone body metabolic process (GO:1902224)4.05029711
84low-density lipoprotein particle remodeling (GO:0034374)4.03686627
85serine family amino acid metabolic process (GO:0009069)3.98362474
86positive regulation of triglyceride lipase activity (GO:0061365)3.97193217
87positive regulation of lipoprotein lipase activity (GO:0051006)3.97193217
88uronic acid metabolic process (GO:0006063)3.93526799
89glucuronate metabolic process (GO:0019585)3.93526799
90complement activation (GO:0006956)3.89896739
91regulation of bile acid biosynthetic process (GO:0070857)3.86448565
92negative regulation of wound healing (GO:0061045)3.86064351
93cellular modified amino acid catabolic process (GO:0042219)3.85941174
94cholesterol homeostasis (GO:0042632)3.85852460
95NADH metabolic process (GO:0006734)3.84597263
96intestinal cholesterol absorption (GO:0030299)3.83915703
97arginine metabolic process (GO:0006525)3.83610109
98phospholipid homeostasis (GO:0055091)3.82887621
99serine family amino acid biosynthetic process (GO:0009070)3.82872316
100fibrinolysis (GO:0042730)3.82371486
101flavonoid metabolic process (GO:0009812)3.81623004
102aldehyde catabolic process (GO:0046185)3.81322197
103regulation of cholesterol homeostasis (GO:2000188)3.81186127
104dicarboxylic acid biosynthetic process (GO:0043650)3.80337909
105positive regulation of lipid catabolic process (GO:0050996)3.79979880
106sterol homeostasis (GO:0055092)3.79853574
107drug transmembrane transport (GO:0006855)3.78830827
108protein-lipid complex assembly (GO:0065005)3.77032089
109regulation of plasminogen activation (GO:0010755)3.76084388
110negative regulation of lipase activity (GO:0060192)3.72994448
111short-chain fatty acid metabolic process (GO:0046459)3.72360775
112blood coagulation, intrinsic pathway (GO:0007597)3.71581776
113plasma lipoprotein particle organization (GO:0071827)3.70660017
114fructose metabolic process (GO:0006000)3.66345701
115drug transport (GO:0015893)3.65074441
116carboxylic acid catabolic process (GO:0046395)3.63214456
117organic acid catabolic process (GO:0016054)3.63214456
118response to nitrosative stress (GO:0051409)3.60251305
119heme transport (GO:0015886)3.59231302
120cofactor catabolic process (GO:0051187)3.58325709
121protein activation cascade (GO:0072376)3.57244880
122lipoprotein metabolic process (GO:0042157)3.57034311
123complement activation, classical pathway (GO:0006958)3.56144609
124opsonization (GO:0008228)3.55366542
125renal system process involved in regulation of blood volume (GO:0001977)3.43187102
126regulation of humoral immune response (GO:0002920)3.41752469
127diacylglycerol metabolic process (GO:0046339)3.41574912
128xenobiotic metabolic process (GO:0006805)3.41398095
129negative regulation of protein activation cascade (GO:2000258)3.38936012
130acute-phase response (GO:0006953)3.32941080
131positive regulation of fatty acid biosynthetic process (GO:0045723)3.32686494
132renal system process involved in regulation of systemic arterial blood pressure (GO:0003071)3.26258051
133protein-lipid complex subunit organization (GO:0071825)3.25756554
134arginine catabolic process (GO:0006527)3.23282476
135lipoprotein transport (GO:0042953)3.09216509
136positive regulation of hemostasis (GO:1900048)3.08443320
137positive regulation of blood coagulation (GO:0030194)3.08443320
138regulation of guanylate cyclase activity (GO:0031282)3.08286422

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1RXR_22158963_ChIP-Seq_LIVER_Mouse8.26807331
2PPARA_22158963_ChIP-Seq_LIVER_Mouse7.17423994
3* EGR1_23403033_ChIP-Seq_LIVER_Mouse6.83629476
4LXR_22158963_ChIP-Seq_LIVER_Mouse6.41299714
5FOXO1_23066095_ChIP-Seq_LIVER_Mouse5.07449015
6CEBPA_23403033_ChIP-Seq_LIVER_Mouse4.99549895
7PPARG_19300518_ChIP-PET_3T3-L1_Mouse4.85451216
8NR1I2_20693526_ChIP-Seq_LIVER_Mouse3.99306351
9CEBPB_23403033_ChIP-Seq_LIVER_Mouse3.80925921
10HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.22203393
11TCF7L2_21901280_ChIP-Seq_H4IIE_Rat2.04530990
12ESR1_17901129_ChIP-ChIP_LIVER_Mouse11.6630897
13TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.91891392
14FOXA2_19822575_ChIP-Seq_HepG2_Human1.61438508
15HTT_18923047_ChIP-ChIP_STHdh_Human1.56091311
16CLOCK_20551151_ChIP-Seq_293T_Human1.51560199
17CDX2_19796622_ChIP-Seq_MESCs_Mouse1.46625535
18* HNF4A_19822575_ChIP-Seq_HepG2_Human1.45506472
19CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.41756049
20GATA1_22025678_ChIP-Seq_K562_Human1.39164531
21STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.37418310
22TRIM28_21343339_ChIP-Seq_HEK293_Human1.35667232
23MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.30408368
24SOX2_27498859_Chip-Seq_STOMACH_Mouse1.27738572
25TCF4_18268006_ChIP-ChIP_LS174T_Human1.26091003
26THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.23806848
27TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.22778433
28IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.22168327
29STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.19174859
30RXRA_24833708_ChIP-Seq_LIVER_Mouse1.16754307
31ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.15060360
32GATA4_25053715_ChIP-Seq_YYC3_Human1.08132320
33ESR1_15608294_ChIP-ChIP_MCF-7_Human1.00020158
34PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.97084813
35GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.96418152
36PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.94590367
37CDX2_20551321_ChIP-Seq_CACO-2_Human0.93008369
38CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.90293321
39RARG_19884340_ChIP-ChIP_MEFs_Mouse0.88893880
40PIAS1_25552417_ChIP-Seq_VCAP_Human0.87488117
41HNFA_21074721_ChIP-Seq_CACO-2_Human0.87034722
42CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.85069623
43KAP1_22055183_ChIP-Seq_ESCs_Mouse0.84190505
44BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.82834305
45AUTS2_25519132_ChIP-Seq_293T-REX_Human0.82096232
46DROSHA_22980978_ChIP-Seq_HELA_Human0.81008657
47SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.80495915
48IRF8_22096565_ChIP-ChIP_GC-B_Human0.80311410
49BP1_19119308_ChIP-ChIP_Hs578T_Human0.79765395
50CTCF_27219007_Chip-Seq_Bcells_Human0.79153750
51TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.78682655
52RARA_24833708_ChIP-Seq_LIVER_Mouse0.78361339
53ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.77996994
54E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.77399344
55ESR2_21235772_ChIP-Seq_MCF-7_Human0.76879101
56SA1_27219007_Chip-Seq_Bcells_Human0.76405133
57KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.75969531
58JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.75917691
59ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.75652811
60SALL4_18804426_ChIP-ChIP_XEN_Mouse0.75366497
61GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.75069999
62Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.74907042
63NR0B1_18358816_ChIP-ChIP_MESCs_Mouse0.74717904
64RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.74404491
65AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.74172026
66NFYA_21822215_ChIP-Seq_K562_Human0.73722240
67PHF8_20622853_ChIP-Seq_HELA_Human0.72666237
68SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.72565285
69SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.71889194
70ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.71539090
71EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.70639292
72NFE2_27457419_Chip-Seq_LIVER_Mouse0.69545064
73BCOR_27268052_Chip-Seq_Bcells_Human0.69309072
74* CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.68500407
75ZNF263_19887448_ChIP-Seq_K562_Human0.68313019
76GATA6_21074721_ChIP-Seq_CACO-2_Human0.67397315
77NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.67375843
78NRF2_20460467_ChIP-Seq_MEFs_Mouse0.67375843
79BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.67372928
80P63_26484246_Chip-Seq_KERATINOCYTES_Human0.65954861
81GATA6_25053715_ChIP-Seq_YYC3_Human0.65392270
82NANOG_20526341_ChIP-Seq_ESCs_Human0.65368641
83RAD21_21589869_ChIP-Seq_MESCs_Mouse0.65308500
84DNAJC2_21179169_ChIP-ChIP_NT2_Human0.65201923
85SOX2_21211035_ChIP-Seq_LN229_Human0.64846536
86RARB_24833708_ChIP-Seq_LIVER_Mouse0.64476613
87* FOXA1_21572438_ChIP-Seq_LNCaP_Human0.63507955
88VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.63240422
89RAC3_21632823_ChIP-Seq_H3396_Human0.62206600
90FOXA1_25552417_ChIP-Seq_VCAP_Human0.62144870
91BCL6_27268052_Chip-Seq_Bcells_Human0.61683131
92SOX2_20726797_ChIP-Seq_SW620_Human0.61018556
93* PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.60955679
94CEBPB_22108803_ChIP-Seq_LS180_Human0.58619763
95MYC_19915707_ChIP-ChIP_AK7_Human0.57768396
96FOXO3_23340844_ChIP-Seq_DLD1_Human0.56879454
97FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.56504527
98NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.55629526
99PPAR_26484153_Chip-Seq_NCI-H1993_Human0.55463718
100LXR_22292898_ChIP-Seq_THP-1_Human0.55272885
101PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.54987545
102FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.54777185
103FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.52988129
104STAT3_1855785_ChIP-Seq_MESCs_Mouse0.52826919
105STAT1_17558387_ChIP-Seq_HELA_Human0.52099844
106ESR1_20079471_ChIP-ChIP_T-47D_Human0.51705158
107EGR1_19032775_ChIP-ChIP_M12_Human0.51596787
108ESET_19884257_ChIP-Seq_ESCs_Mouse0.50987734
109P53_21459846_ChIP-Seq_SAOS-2_Human0.49532056
110ESR1_21235772_ChIP-Seq_MCF-7_Human0.49384141
111PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.49074561
112NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.48218511
113* AR_20517297_ChIP-Seq_VCAP_Human0.47945049
114BCAT_22108803_ChIP-Seq_LS180_Human0.46610547
115CBP_21632823_ChIP-Seq_H3396_Human0.45904718
116GATA2_19941826_ChIP-Seq_K562_Human0.45874390
117SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.44597639
118PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.43814743
119* TAF2_19829295_ChIP-Seq_ESCs_Human0.43743718
120SRY_22984422_ChIP-ChIP_TESTIS_Rat0.41435040
121GATA1_19941826_ChIP-Seq_K562_Human0.41342928
122* GATA1_19941827_ChIP-Seq_MEL_Mouse0.41074182
123CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.41015929
124CDX2_22108803_ChIP-Seq_LS180_Human0.40814141
125FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.40080024
126ERG_21242973_ChIP-ChIP_JURKAT_Human0.40006330
127GATA3_24758297_ChIP-Seq_MCF-7_Human0.39842277
128EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.38993481
129STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.37938807
130SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.37745793
131MYC_27129775_Chip-Seq_CORNEA_Mouse0.37162348
132ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.36679064
133CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse0.36497387
134LUZP1_20508642_ChIP-Seq_ESCs_Mouse0.36130749
135RACK7_27058665_Chip-Seq_MCF-7_Human0.35307948

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system8.41353894
2MP0005360_urolithiasis7.56430095
3MP0005085_abnormal_gallbladder_physiolo6.39234154
4MP0005365_abnormal_bile_salt6.03134283
5MP0008875_abnormal_xenobiotic_pharmacok5.20547652
6MP0003806_abnormal_nucleotide_metabolis4.20141080
7MP0003252_abnormal_bile_duct3.93084212
8MP0010329_abnormal_lipoprotein_level3.58119881
9MP0009840_abnormal_foam_cell3.32220096
10MP0001666_abnormal_nutrient_absorption2.96544737
11MP0005083_abnormal_biliary_tract2.93237343
12MP0003195_calcinosis2.62036242
13MP0005332_abnormal_amino_acid2.60377121
14MP0003191_abnormal_cellular_cholesterol2.38602796
15MP0004019_abnormal_vitamin_homeostasis2.23625378
16MP0000609_abnormal_liver_physiology2.12766456
17MP0002118_abnormal_lipid_homeostasis2.09266031
18MP0002138_abnormal_hepatobiliary_system2.00605857
19MP0003868_abnormal_feces_composition1.89547410
20MP0003183_abnormal_peptide_metabolism1.84584991
21MP0005319_abnormal_enzyme/_coenzyme1.76389812
22MP0001764_abnormal_homeostasis1.58167741
23MP0009697_abnormal_copulation1.57743239
24MP0005584_abnormal_enzyme/coenzyme_acti1.51330163
25MP0003011_delayed_dark_adaptation1.40022885
26MP0005451_abnormal_body_composition1.39716670
27MP0002822_catalepsy1.37089552
28MP0004043_abnormal_pH_regulation1.28480797
29MP0009643_abnormal_urine_homeostasis1.26331171
30MP0003879_abnormal_hair_cell1.23809588
31MP0000566_synostosis1.22905750
32MP0004147_increased_porphyrin_level1.20846685
33MP0010155_abnormal_intestine_physiology1.19771333
34MP0003866_abnormal_defecation1.17544198
35MP0003186_abnormal_redox_activity1.15796389
36MP0003705_abnormal_hypodermis_morpholog1.14405459
37MP0000598_abnormal_liver_morphology1.10811819
38MP0003656_abnormal_erythrocyte_physiolo1.09616737
39MP0002254_reproductive_system_inflammat1.08825668
40MP0005647_abnormal_sex_gland1.06534114
41MP0000604_amyloidosis1.03975727
42MP0009764_decreased_sensitivity_to1.02286999
43MP0010386_abnormal_urinary_bladder1.01133272
44MP0001664_abnormal_digestion1.00412078
45MP0005636_abnormal_mineral_homeostasis0.99755973
46MP0009763_increased_sensitivity_to0.95996086
47MP0008469_abnormal_protein_level0.85947603
48MP0009642_abnormal_blood_homeostasis0.85926553
49MP0005409_darkened_coat_color0.85705967
50MP0005084_abnormal_gallbladder_morpholo0.85601575
51MP0009379_abnormal_foot_pigmentation0.82266533
52MP0000477_abnormal_intestine_morphology0.81967371
53MP0001663_abnormal_digestive_system0.81438109
54MP0010368_abnormal_lymphatic_system0.80504401
55MP0005408_hypopigmentation0.79343885
56MP0002876_abnormal_thyroid_physiology0.78864660
57MP0009765_abnormal_xenobiotic_induced0.76971365
58MP0000462_abnormal_digestive_system0.76153170
59MP0006036_abnormal_mitochondrial_physio0.76042285
60MP0005376_homeostasis/metabolism_phenot0.75091064
61MP0002078_abnormal_glucose_homeostasis0.73925040
62MP0000538_abnormal_urinary_bladder0.71785221
63MP0005334_abnormal_fat_pad0.68015126
64MP0010234_abnormal_vibrissa_follicle0.67633251
65MP0005381_digestive/alimentary_phenotyp0.67573731
66MP0002971_abnormal_brown_adipose0.66102945
67MP0009785_altered_susceptibility_to0.66018489
68MP0005220_abnormal_exocrine_pancreas0.65612602
69MP0009053_abnormal_anal_canal0.64049089
70MP0001661_extended_life_span0.63480845
71MP0005266_abnormal_metabolism0.60820548
72MP0005670_abnormal_white_adipose0.60506166
73MP0004130_abnormal_muscle_cell0.60295490
74MP0005448_abnormal_energy_balance0.60026518
75MP0003690_abnormal_glial_cell0.59486615
76MP0003329_amyloid_beta_deposits0.58877184
77MP0001756_abnormal_urination0.58865217
78MP0005167_abnormal_blood-brain_barrier0.57926738
79MP0001501_abnormal_sleep_pattern0.57185844
80MP0005535_abnormal_body_temperature0.56940710
81MP0006035_abnormal_mitochondrial_morpho0.56366828
82MP0000639_abnormal_adrenal_gland0.52838315
83MP0002168_other_aberrant_phenotype0.52700822
84MP0001873_stomach_inflammation0.52249278
85MP0005464_abnormal_platelet_physiology0.49460304
86MP0000537_abnormal_urethra_morphology0.48679019
87MP0003283_abnormal_digestive_organ0.48455037
88MP0008873_increased_physiological_sensi0.48453560
89MP0010352_gastrointestinal_tract_polyps0.48411572
90MP0003724_increased_susceptibility_to0.47827568
91MP0004264_abnormal_extraembryonic_tissu0.46926919
92MP0002136_abnormal_kidney_physiology0.46688649
93MP0000678_abnormal_parathyroid_gland0.46500614
94MP0000490_abnormal_crypts_of0.46264251
95MP0009384_cardiac_valve_regurgitation0.45792602
96MP0003638_abnormal_response/metabolism_0.45030552
97MP0005187_abnormal_penis_morphology0.44937653
98MP0002089_abnormal_postnatal_growth/wei0.44658257
99MP0006082_CNS_inflammation0.44072476
100MP0002796_impaired_skin_barrier0.43983605
101MP0005395_other_phenotype0.43036841
102MP0003718_maternal_effect0.42938691
103MP0002928_abnormal_bile_duct0.42914476
104MP0005166_decreased_susceptibility_to0.42847485
105MP0003953_abnormal_hormone_level0.42635899
106MP0004782_abnormal_surfactant_physiolog0.41542320
107MP0002098_abnormal_vibrissa_morphology0.41391945
108MP0008872_abnormal_physiological_respon0.39980855
109MP0008874_decreased_physiological_sensi0.37612325
110MP0002166_altered_tumor_susceptibility0.37109953
111MP0003075_altered_response_to0.36874849
112MP0003436_decreased_susceptibility_to0.36868880
113MP0003959_abnormal_lean_body0.36110924
114MP0005248_abnormal_Harderian_gland0.35260718
115MP0000249_abnormal_blood_vessel0.33416415
116MP0009115_abnormal_fat_cell0.32917308
117MP0000230_abnormal_systemic_arterial0.31985903
118MP0003045_fibrosis0.31820829
119MP0001845_abnormal_inflammatory_respons0.30486131
120MP0002837_dystrophic_cardiac_calcinosis0.30125693
121MP0003300_gastrointestinal_ulcer0.29835254
122MP0002132_abnormal_respiratory_system0.29662874
123MP0000579_abnormal_nail_morphology0.28414713
124MP0005666_abnormal_adipose_tissue0.28306188
125MP0001881_abnormal_mammary_gland0.28123074
126MP0004883_abnormal_blood_vessel0.27767428
127MP0002060_abnormal_skin_morphology0.27000395
128MP0009672_abnormal_birth_weight0.26952428
129MP0001243_abnormal_dermal_layer0.26498921
130MP0001765_abnormal_ion_homeostasis0.26262198
131MP0005058_abnormal_lysosome_morphology0.26165538

Predicted human phenotypes

RankGene SetZ-score
1Intrahepatic cholestasis (HP:0001406)7.33443182
2Deep venous thrombosis (HP:0002625)7.20596868
3Abnormality of aromatic amino acid family metabolism (HP:0004338)7.14743279
4Hypobetalipoproteinemia (HP:0003563)6.69303143
5Abnormality of monocarboxylic acid metabolism (HP:0010996)6.65729521
6Prolonged partial thromboplastin time (HP:0003645)6.40149092
7Xanthomatosis (HP:0000991)6.22919891
8Hyperlipoproteinemia (HP:0010980)5.49592662
9Hypolipoproteinemia (HP:0010981)4.92108413
10Complement deficiency (HP:0004431)4.92070856
11Hyperammonemia (HP:0001987)4.57326642
12Joint hemorrhage (HP:0005261)4.56969609
13Abnormality of the level of lipoprotein cholesterol (HP:0010979)4.48791753
14Epidermoid cyst (HP:0200040)4.37706936
15Hyperglycinemia (HP:0002154)4.34930800
16Abnormality of the common coagulation pathway (HP:0010990)4.32782148
17Fat malabsorption (HP:0002630)4.31495542
18Abnormality of glutamine family amino acid metabolism (HP:0010902)4.17049886
19Hypoalphalipoproteinemia (HP:0003233)4.16861978
20Abnormality of sulfur amino acid metabolism (HP:0004339)4.14273607
21Ketosis (HP:0001946)4.12668020
22Hypoglycemic coma (HP:0001325)4.02325594
23Conjugated hyperbilirubinemia (HP:0002908)4.00155058
24Abnormality of methionine metabolism (HP:0010901)3.99226557
25Abnormality of aspartate family amino acid metabolism (HP:0010899)3.96903691
26Hyperglycinuria (HP:0003108)3.91920057
27Abnormality of serine family amino acid metabolism (HP:0010894)3.84332546
28Abnormality of glycine metabolism (HP:0010895)3.84332546
29Hypercholesterolemia (HP:0003124)3.69689222
30Abnormality of complement system (HP:0005339)3.61359110
31Abnormality of the intrinsic pathway (HP:0010989)3.61286386
32Abnormality of pyrimidine metabolism (HP:0004353)3.59685534
33Hyperbilirubinemia (HP:0002904)3.43906534
34Nephritis (HP:0000123)3.38748135
35Abnormality of fatty-acid metabolism (HP:0004359)3.32184075
36Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.29448173
37Ileus (HP:0002595)3.25397548
38Steatorrhea (HP:0002570)3.13309959
39Abnormality of nucleobase metabolism (HP:0010932)3.10079454
40Spontaneous abortion (HP:0005268)3.03304839
41Ketoacidosis (HP:0001993)3.01729122
42Malnutrition (HP:0004395)2.96936388
43Potter facies (HP:0002009)2.96754464
44Facial shape deformation (HP:0011334)2.96754464
45Delayed CNS myelination (HP:0002188)2.93059327
46Metabolic alkalosis (HP:0200114)2.91192601
47Abnormality of serum amino acid levels (HP:0003112)2.89649922
48Hepatocellular carcinoma (HP:0001402)2.88288118
49Myocardial infarction (HP:0001658)2.85819755
50Abnormality of purine metabolism (HP:0004352)2.85276413
51Hypochromic microcytic anemia (HP:0004840)2.80451435
52Metabolic acidosis (HP:0001942)2.76635978
53Acanthocytosis (HP:0001927)2.74961330
54Osteomalacia (HP:0002749)2.72394630
55Abnormality of dicarboxylic acid metabolism (HP:0010995)2.67229117
56Dicarboxylic aciduria (HP:0003215)2.67229117
57Vascular calcification (HP:0004934)2.67143331
58Skin nodule (HP:0200036)2.65386518
59Hyperactive renin-angiotensin system (HP:0000841)2.64770163
60Widely patent fontanelles and sutures (HP:0004492)2.64137480
61Lethargy (HP:0001254)2.61595745
62Hypoglycemic seizures (HP:0002173)2.59734126
63Abdominal distention (HP:0003270)2.56119443
64Systemic lupus erythematosus (HP:0002725)2.54517935
65Hyperphosphaturia (HP:0003109)2.46930625
66Abnormal gallbladder physiology (HP:0012438)2.46337284
67Cholecystitis (HP:0001082)2.46337284
68Abnormal gallbladder morphology (HP:0012437)2.44356486
69Gout (HP:0001997)2.43673854
70Glomerulonephritis (HP:0000099)2.39522157
71Cholelithiasis (HP:0001081)2.39374470
72Abnormality of the vitamin B12 metabolism (HP:0004341)2.38136104
73Cardiovascular calcification (HP:0011915)2.36361943
74Late onset (HP:0003584)2.35526785
75Spastic diplegia (HP:0001264)2.33624230
76Cerebral edema (HP:0002181)2.31954927
77Confusion (HP:0001289)2.29961467
78Irritability (HP:0000737)2.29747715
79Esophageal varix (HP:0002040)2.29208600
80Hypophosphatemia (HP:0002148)2.28674791
81Decreased circulating renin level (HP:0003351)2.28081874
82Mitral stenosis (HP:0001718)2.27962605
83Abnormality of vitamin B metabolism (HP:0004340)2.25779824
84Gingival bleeding (HP:0000225)2.24442564
85Amyloidosis (HP:0011034)2.23206129
86Pancreatitis (HP:0001733)2.20950776
87Abnormal urine phosphate concentration (HP:0012599)2.19974465
88Hyperuricemia (HP:0002149)2.18068577
89Increased purine levels (HP:0004368)2.18068577
90Nephrolithiasis (HP:0000787)2.17832466
91Sensorimotor neuropathy (HP:0007141)2.17649241
92Neonatal onset (HP:0003623)2.17522326
93Menorrhagia (HP:0000132)2.13846671
94Generalized aminoaciduria (HP:0002909)2.12865171
95Flat acetabular roof (HP:0003180)2.12011998
96Opisthotonus (HP:0002179)2.09879732
97Poikilocytosis (HP:0004447)2.08888801
98Vomiting (HP:0002013)2.08027483
99Hyperinsulinemic hypoglycemia (HP:0000825)2.07909410
100Abnormality of renin-angiotensin system (HP:0000847)2.07005659
101Brushfield spots (HP:0001088)2.05242766
102Abnormal cartilage morphology (HP:0002763)2.04649904
103Abnormality of alkaline phosphatase activity (HP:0004379)2.04605760
104Chronic diarrhea (HP:0002028)2.01700148
105Hemorrhage of the eye (HP:0011885)2.01612634
106Enlarged kidneys (HP:0000105)1.99733662
107Thrombophlebitis (HP:0004418)1.99131382
108Abnormality of iron homeostasis (HP:0011031)1.98896608
109Abnormality of the gallbladder (HP:0005264)1.98327794
110Rickets (HP:0002748)1.97925953
111Recurrent gram-negative bacterial infections (HP:0005420)1.97305475
112Abnormality of transition element cation homeostasis (HP:0011030)1.96952380
113Elevated alkaline phosphatase (HP:0003155)1.95273207
114Focal segmental glomerulosclerosis (HP:0000097)1.94006655
115Abnormality of chloride homeostasis (HP:0011422)1.93183692
116Hydroxyprolinuria (HP:0003080)1.92818751
117Abnormality of proline metabolism (HP:0010907)1.92818751
118Cerebral palsy (HP:0100021)1.92328029
119Symptomatic seizures (HP:0011145)1.90172155
120Purpura (HP:0000979)1.90078376
121Renal tubular acidosis (HP:0001947)1.89585617
122Renal cortical cysts (HP:0000803)1.88590130
123Fair hair (HP:0002286)1.88379156
124Abnormality of vitamin metabolism (HP:0100508)1.88338386
125Arthropathy (HP:0003040)1.87905771
126Alkalosis (HP:0001948)1.86237890
127Hypophosphatemic rickets (HP:0004912)1.84923252
128Hypokalemia (HP:0002900)1.84430637
129Abnormality of urine glucose concentration (HP:0011016)1.84131776
130Glycosuria (HP:0003076)1.84131776
131Abnormal enzyme/coenzyme activity (HP:0012379)1.83801854
132Proximal tubulopathy (HP:0000114)1.83082304
133Protuberant abdomen (HP:0001538)1.81836943
134Elevated hepatic transaminases (HP:0002910)1.80943923
135Pigmentary retinal degeneration (HP:0001146)1.76925560

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK6.46847195
2ACVR1B5.42713705
3MST1R4.81055276
4FGFR44.10731816
5SIK14.07221874
6ERN14.00731136
7EPHA23.74422591
8TAOK33.33596163
9FRK2.90025186
10INSRR2.70557343
11ERBB42.35364987
12PKN22.17826868
13PIK3CA2.12161375
14PIK3CG2.08263828
15MAP2K42.04342731
16MET1.76240851
17FLT31.70475763
18PTK61.65124773
19MAPK111.63445452
20TYK21.57606397
21LATS11.47518567
22DAPK21.45904307
23STK391.41058203
24TRIB31.35505158
25ABL21.25115311
26KDR1.21320582
27FER1.18542287
28OXSR11.17885538
29NEK91.17818735
30PDK21.16635835
31PRKAA21.13428267
32MAP3K111.11665710
33TAOK11.10514403
34GRK61.10371447
35ERBB21.09253786
36MAP2K21.09241779
37JAK21.08360878
38FGFR21.07318532
39MAP3K71.07017648
40MAP3K101.00055980
41NLK0.99980355
42BLK0.97899183
43TBK10.95865368
44MAPK150.95120860
45PRPF4B0.93703044
46MAP3K140.92094916
47TIE10.91872773
48IRAK30.91137922
49MAP3K20.89743448
50MAPK40.87653322
51JAK10.86728722
52MAP2K60.82956833
53EPHB10.82868206
54PRKCZ0.81971053
55MAP2K30.81873820
56PINK10.80903060
57CSK0.79741235
58PBK0.74840517
59MAP3K30.73625844
60MAP2K10.72449407
61PRKACG0.72171909
62CDK60.70243400
63STK38L0.69398323
64CAMK2G0.67897486
65DYRK1B0.67774354
66GRK10.67392466
67CAMK1D0.67074012
68RIPK10.64218057
69MAP3K10.64175039
70PRKAA10.63428346
71EPHA30.61299521
72GSK3A0.60864141
73MAP4K10.60173435
74TESK20.58990708
75PTK20.57824753
76NUAK10.56767769
77MAPK120.54196080
78KSR20.53578493
79TNK20.53415750
80PRKG20.51483755
81PDPK10.51111116
82SGK30.50778424
83MAP3K120.49841923
84MYLK0.49237904
85MATK0.48146024
86EPHB20.47539027
87TNIK0.47425100
88PRKG10.47138359
89RET0.44343634
90CASK0.44236292
91DDR20.44087790
92PRKACA0.44017176
93PDGFRA0.43827197
94IKBKE0.43360916
95IGF1R0.43306936
96PRKCQ0.43157382
97MAPK70.42667256
98LMTK20.41656542
99SRC0.41386983
100CDC42BPA0.40607390
101FGFR30.39649705
102TGFBR20.39562287
103RIPK40.38984502
104ZAP700.37429557
105MST40.36524685
106CSNK1G10.35422992
107MAP3K50.34526182
108ICK0.34153159
109WNK40.33909276
110BCR0.33442915
111PIM20.33116319
112ADRBK20.31918444
113CDK40.31182871
114PRKCA0.30789522
115CAMK2D0.30258672
116CSF1R0.30087609
117PDK10.28906408
118TAOK20.28577223
119MAP3K130.28437067
120YES10.28140998
121SGK2230.26793875
122SGK4940.26793875
123PRKCI0.26185729
124MAPKAPK30.26101509
125PRKCB0.25781864
126SGK10.25142452
127CSNK1A10.23943278
128AKT30.23700629
129EPHA40.23209743
130SGK20.23066995
131MTOR0.22857544
132PRKCG0.22643567
133EGFR0.21894462
134IRAK20.21646632
135CAMK40.19993451
136PRKACB0.16503280
137CAMK1G0.16079204
138IRAK10.15407809
139ABL10.15003367

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001204.28167634
2Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.50167902
3Nitrogen metabolism_Homo sapiens_hsa009103.48146805
4Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.06649834
5Arginine biosynthesis_Homo sapiens_hsa002202.89293466
6Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.70447963
7Tryptophan metabolism_Homo sapiens_hsa003802.66631827
8Complement and coagulation cascades_Homo sapiens_hsa046102.60604521
9Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.54924341
10Fatty acid degradation_Homo sapiens_hsa000712.50616595
11Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.39078614
12Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.36984569
13Pentose and glucuronate interconversions_Homo sapiens_hsa000402.34698507
14Drug metabolism - cytochrome P450_Homo sapiens_hsa009822.24048745
15Butanoate metabolism_Homo sapiens_hsa006502.17930765
16Chemical carcinogenesis_Homo sapiens_hsa052042.02091063
17Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009802.01314459
18Peroxisome_Homo sapiens_hsa041462.01172292
19Histidine metabolism_Homo sapiens_hsa003402.00787840
20Steroid hormone biosynthesis_Homo sapiens_hsa001401.91159121
21Propanoate metabolism_Homo sapiens_hsa006401.89880343
22PPAR signaling pathway_Homo sapiens_hsa033201.88149511
23Sulfur metabolism_Homo sapiens_hsa009201.87415530
24Fatty acid metabolism_Homo sapiens_hsa012121.81813059
25Drug metabolism - other enzymes_Homo sapiens_hsa009831.79460126
26Retinol metabolism_Homo sapiens_hsa008301.76709551
27Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.73122863
28beta-Alanine metabolism_Homo sapiens_hsa004101.68387202
29Staphylococcus aureus infection_Homo sapiens_hsa051501.67493590
30Caffeine metabolism_Homo sapiens_hsa002321.63935841
31Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.63197979
32Bile secretion_Homo sapiens_hsa049761.62779012
33Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.58642691
34Selenocompound metabolism_Homo sapiens_hsa004501.49634596
35Phenylalanine metabolism_Homo sapiens_hsa003601.48458086
36Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.47161513
37Fat digestion and absorption_Homo sapiens_hsa049751.45592672
382-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.40295535
39Starch and sucrose metabolism_Homo sapiens_hsa005001.39774490
40Tyrosine metabolism_Homo sapiens_hsa003501.37538398
41Pyruvate metabolism_Homo sapiens_hsa006201.37288184
42Folate biosynthesis_Homo sapiens_hsa007901.33399465
43Fatty acid elongation_Homo sapiens_hsa000621.33059810
44ABC transporters_Homo sapiens_hsa020101.26604445
45Sulfur relay system_Homo sapiens_hsa041221.25270235
46Cysteine and methionine metabolism_Homo sapiens_hsa002701.24977777
47Maturity onset diabetes of the young_Homo sapiens_hsa049501.17287826
48Steroid biosynthesis_Homo sapiens_hsa001001.13956687
49Carbon metabolism_Homo sapiens_hsa012001.11392724
50Biosynthesis of amino acids_Homo sapiens_hsa012301.10394599
51Cyanoamino acid metabolism_Homo sapiens_hsa004601.05070160
52Vitamin digestion and absorption_Homo sapiens_hsa049770.99261389
53Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.96459844
54Arginine and proline metabolism_Homo sapiens_hsa003300.95563572
55Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.92785844
56Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.90284231
57Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.86799805
58Vitamin B6 metabolism_Homo sapiens_hsa007500.80654295
59Lysine degradation_Homo sapiens_hsa003100.77596216
60Glycerolipid metabolism_Homo sapiens_hsa005610.77278013
61Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.74593469
62Glutathione metabolism_Homo sapiens_hsa004800.73744510
63Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.73388860
64One carbon pool by folate_Homo sapiens_hsa006700.67973568
65Pentose phosphate pathway_Homo sapiens_hsa000300.62684923
66Fatty acid biosynthesis_Homo sapiens_hsa000610.53419784
67Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.48794156
68Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.46918586
69Metabolic pathways_Homo sapiens_hsa011000.46862299
70Galactose metabolism_Homo sapiens_hsa000520.41847756
71Fructose and mannose metabolism_Homo sapiens_hsa000510.36669965
72alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.34933966
73Prion diseases_Homo sapiens_hsa050200.27166097
74Pancreatic secretion_Homo sapiens_hsa049720.26743360
75Linoleic acid metabolism_Homo sapiens_hsa005910.26138864
76Other glycan degradation_Homo sapiens_hsa005110.22711424
77Glycerophospholipid metabolism_Homo sapiens_hsa005640.19825953
78Insulin resistance_Homo sapiens_hsa049310.19643081
79Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.18824529
80Sphingolipid metabolism_Homo sapiens_hsa006000.18652816
81Adipocytokine signaling pathway_Homo sapiens_hsa049200.16542043
82Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.07784651
83Mineral absorption_Homo sapiens_hsa049780.05723910
84Glucagon signaling pathway_Homo sapiens_hsa049220.03686787
85Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.02656656
86Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.00639587
87Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141-0.2199782
88Ether lipid metabolism_Homo sapiens_hsa00565-0.2195193
89Pertussis_Homo sapiens_hsa05133-0.2103267
90Glycosaminoglycan degradation_Homo sapiens_hsa00531-0.2031906
91Systemic lupus erythematosus_Homo sapiens_hsa05322-0.1976864
92Protein digestion and absorption_Homo sapiens_hsa04974-0.1909980
93Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604-0.1891739
94Bladder cancer_Homo sapiens_hsa05219-0.1862678
95Thyroid hormone synthesis_Homo sapiens_hsa04918-0.1608162
96Central carbon metabolism in cancer_Homo sapiens_hsa05230-0.1525285
97Hepatitis C_Homo sapiens_hsa05160-0.1344203
98Carbohydrate digestion and absorption_Homo sapiens_hsa04973-0.1266631
99Insulin signaling pathway_Homo sapiens_hsa04910-0.1247818
100African trypanosomiasis_Homo sapiens_hsa05143-0.1187336
101Arachidonic acid metabolism_Homo sapiens_hsa00590-0.1130639
102Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534-0.1106487
103Amoebiasis_Homo sapiens_hsa05146-0.1077987
104Ovarian steroidogenesis_Homo sapiens_hsa04913-0.1059954
105Renin secretion_Homo sapiens_hsa04924-0.0772252
106Asthma_Homo sapiens_hsa05310-0.0649763
107Renin-angiotensin system_Homo sapiens_hsa04614-0.0364048
108Intestinal immune network for IgA production_Homo sapiens_hsa04672-0.0315840
109Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960-0.0284614
110AMPK signaling pathway_Homo sapiens_hsa04152-0.0177251
111Serotonergic synapse_Homo sapiens_hsa04726-0.0082789

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