SLC22A7

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney. Alternatively spliced transcript variants encoding different isoforms have been described. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1epoxygenase P450 pathway (GO:0019373)7.69478115
2omega-hydroxylase P450 pathway (GO:0097267)7.46512088
3erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)7.27222970
4L-phenylalanine catabolic process (GO:0006559)7.27222970
5aromatic amino acid family catabolic process (GO:0009074)7.22716649
6indole-containing compound catabolic process (GO:0042436)7.11942697
7indolalkylamine catabolic process (GO:0046218)7.11942697
8tryptophan catabolic process (GO:0006569)7.11942697
9L-phenylalanine metabolic process (GO:0006558)7.11477823
10erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)7.11477823
11fibrinolysis (GO:0042730)7.00685092
12lysine catabolic process (GO:0006554)6.99096733
13lysine metabolic process (GO:0006553)6.99096733
14cysteine metabolic process (GO:0006534)6.80254439
15kynurenine metabolic process (GO:0070189)6.80075930
16glyoxylate metabolic process (GO:0046487)6.64829231
17tryptophan metabolic process (GO:0006568)6.62702542
18blood coagulation, intrinsic pathway (GO:0007597)6.26178332
19urate metabolic process (GO:0046415)6.08616847
20drug transmembrane transport (GO:0006855)5.94818665
21oxidative demethylation (GO:0070989)5.89567010
22drug metabolic process (GO:0017144)5.86461904
23regulation of plasminogen activation (GO:0010755)5.66600452
24bile acid biosynthetic process (GO:0006699)5.60863959
25phenylpropanoid metabolic process (GO:0009698)5.56393551
26serine family amino acid catabolic process (GO:0009071)5.48884334
27phospholipid efflux (GO:0033700)5.36862783
28fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)5.35358712
29aromatic amino acid family metabolic process (GO:0009072)5.27729498
30sulfur amino acid catabolic process (GO:0000098)5.26408241
31negative regulation of blood coagulation (GO:0030195)5.15582004
32negative regulation of hemostasis (GO:1900047)5.15582004
33homocysteine metabolic process (GO:0050667)5.14391922
34drug transport (GO:0015893)5.06250136
35cellular ketone body metabolic process (GO:0046950)5.02897773
36amino-acid betaine metabolic process (GO:0006577)5.02217010
37indolalkylamine metabolic process (GO:0006586)4.98951601
38glutamate metabolic process (GO:0006536)4.94669679
39protein activation cascade (GO:0072376)4.92266707
40aspartate family amino acid catabolic process (GO:0009068)4.86809194
41serine family amino acid metabolic process (GO:0009069)4.83457634
42cellular biogenic amine catabolic process (GO:0042402)4.83142840
43amine catabolic process (GO:0009310)4.83142840
44alpha-amino acid catabolic process (GO:1901606)4.81058208
45ethanol metabolic process (GO:0006067)4.78968318
46cellular modified amino acid catabolic process (GO:0042219)4.74944035
47urea metabolic process (GO:0019627)4.71311192
48urea cycle (GO:0000050)4.71311192
492-oxoglutarate metabolic process (GO:0006103)4.70153979
50negative regulation of coagulation (GO:0050819)4.68790258
51alpha-linolenic acid metabolic process (GO:0036109)4.68633621
52bile acid metabolic process (GO:0008206)4.65624778
53negative regulation of wound healing (GO:0061045)4.63068037
54triglyceride-rich lipoprotein particle remodeling (GO:0034370)4.60212033
55positive regulation of lipoprotein lipase activity (GO:0051006)4.60186246
56positive regulation of triglyceride lipase activity (GO:0061365)4.60186246
57positive regulation of hemostasis (GO:1900048)4.58832061
58positive regulation of blood coagulation (GO:0030194)4.58832061
59alkaloid metabolic process (GO:0009820)4.58389726
60short-chain fatty acid metabolic process (GO:0046459)4.57382152
61cellular amino acid catabolic process (GO:0009063)4.56891562
62cholesterol efflux (GO:0033344)4.56598469
63benzene-containing compound metabolic process (GO:0042537)4.51687254
64acetyl-CoA metabolic process (GO:0006084)4.51090529
65regulation of humoral immune response (GO:0002920)4.46225341
66acute-phase response (GO:0006953)4.46106248
67complement activation, alternative pathway (GO:0006957)4.46022033
68complement activation, classical pathway (GO:0006958)4.45774009
69complement activation (GO:0006956)4.45501391
70serine family amino acid biosynthetic process (GO:0009070)4.44647095
71nitrogen cycle metabolic process (GO:0071941)4.40668700
72tyrosine metabolic process (GO:0006570)4.36762678
73ketone body metabolic process (GO:1902224)4.34795608
74regulation of protein activation cascade (GO:2000257)4.34688022
75protein carboxylation (GO:0018214)4.34619327
76peptidyl-glutamic acid carboxylation (GO:0017187)4.34619327
77negative regulation of lipase activity (GO:0060192)4.31495428
78drug catabolic process (GO:0042737)4.30399316
79negative regulation of fibrinolysis (GO:0051918)4.30327116
80organic cation transport (GO:0015695)4.25414509
81positive regulation of coagulation (GO:0050820)4.22474105
82response to mercury ion (GO:0046689)4.20581349
83coenzyme catabolic process (GO:0009109)4.19571158
84S-adenosylmethionine metabolic process (GO:0046500)4.18768815
85valine metabolic process (GO:0006573)4.15651053
86regulation of fibrinolysis (GO:0051917)4.13909776
87negative regulation of protein activation cascade (GO:2000258)4.12698466
88regulation of complement activation (GO:0030449)4.10616111
89glycine metabolic process (GO:0006544)4.10033466
90regulation of lipoprotein particle clearance (GO:0010984)4.01608084
91high-density lipoprotein particle remodeling (GO:0034375)4.01314247
92carboxylic acid catabolic process (GO:0046395)4.00981148
93organic acid catabolic process (GO:0016054)4.00981148
94hormone catabolic process (GO:0042447)3.99711395
95fatty acid beta-oxidation (GO:0006635)3.99082978
96fatty acid oxidation (GO:0019395)3.98768495
97dicarboxylic acid biosynthetic process (GO:0043650)3.98400063
98exogenous drug catabolic process (GO:0042738)3.96926892
99aldehyde catabolic process (GO:0046185)3.96474438
100carnitine metabolic process (GO:0009437)3.94040670
101very-low-density lipoprotein particle assembly (GO:0034379)3.91559071
102ethanol oxidation (GO:0006069)3.91481041
103lipid oxidation (GO:0034440)3.91142110
104heme transport (GO:0015886)3.91138478
105intestinal cholesterol absorption (GO:0030299)3.90765808
106cellular glucuronidation (GO:0052695)3.89723713
107plasma lipoprotein particle clearance (GO:0034381)3.87892303
108negative regulation of sterol transport (GO:0032372)3.87225430
109negative regulation of cholesterol transport (GO:0032375)3.87225430
110branched-chain amino acid metabolic process (GO:0009081)3.86693172
111phosphate ion transport (GO:0006817)3.84711068
112phosphate ion transmembrane transport (GO:0035435)3.81503617
113indole-containing compound metabolic process (GO:0042430)3.76355492
114bile acid and bile salt transport (GO:0015721)3.75994970
115regulation of triglyceride catabolic process (GO:0010896)3.74261581
116acylglycerol homeostasis (GO:0055090)3.73664129
117triglyceride homeostasis (GO:0070328)3.73664129
118cytolysis (GO:0019835)3.71500740
119monocarboxylic acid catabolic process (GO:0072329)3.69712191
120fatty acid catabolic process (GO:0009062)3.68511236
121fat-soluble vitamin biosynthetic process (GO:0042362)3.66467610
122regulation of cholesterol homeostasis (GO:2000188)3.66075060
123branched-chain amino acid catabolic process (GO:0009083)3.64610544
124glucuronate metabolic process (GO:0019585)3.62679740
125uronic acid metabolic process (GO:0006063)3.62679740
126opsonization (GO:0008228)3.60214039
127arginine metabolic process (GO:0006525)3.59735920
128steroid catabolic process (GO:0006706)3.58178830
129fructose metabolic process (GO:0006000)3.58101333
130flavonoid metabolic process (GO:0009812)3.57895651
131positive regulation of fatty acid biosynthetic process (GO:0045723)3.50899578
132positive regulation of lipid catabolic process (GO:0050996)3.50817706
133acute inflammatory response (GO:0002526)3.50667602
134reverse cholesterol transport (GO:0043691)3.48438609
135imidazole-containing compound metabolic process (GO:0052803)3.47275335
136negative regulation of complement activation (GO:0045916)3.46503544
137regulation of cholesterol esterification (GO:0010872)3.46417356
138regulation of apoptotic cell clearance (GO:2000425)3.46106799
139plasma lipoprotein particle remodeling (GO:0034369)3.45967214
140protein-lipid complex remodeling (GO:0034368)3.45967214
141macromolecular complex remodeling (GO:0034367)3.45967214
142dicarboxylic acid metabolic process (GO:0043648)3.44215615
143negative regulation of lipid transport (GO:0032369)3.42188861
144small molecule catabolic process (GO:0044282)3.41434941
145tricarboxylic acid metabolic process (GO:0072350)3.40449233
146response to nitrosative stress (GO:0051409)3.40378024

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1RXR_22158963_ChIP-Seq_LIVER_Mouse8.08998858
2PPARA_22158963_ChIP-Seq_LIVER_Mouse6.96611099
3EGR1_23403033_ChIP-Seq_LIVER_Mouse6.24422892
4* LXR_22158963_ChIP-Seq_LIVER_Mouse6.16795383
5PPARG_19300518_ChIP-PET_3T3-L1_Mouse5.16690201
6FOXO1_23066095_ChIP-Seq_LIVER_Mouse4.71082060
7CEBPA_23403033_ChIP-Seq_LIVER_Mouse4.37417065
8NR1I2_20693526_ChIP-Seq_LIVER_Mouse3.83161954
9CEBPB_23403033_ChIP-Seq_LIVER_Mouse3.73698663
10HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.44926022
11TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.35507121
12TCF7L2_21901280_ChIP-Seq_H4IIE_Rat2.13049050
13ESR1_17901129_ChIP-ChIP_LIVER_Mouse11.2857040
14NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.68348623
15CLOCK_20551151_ChIP-Seq_293T_Human1.66145457
16* FOXA2_19822575_ChIP-Seq_HepG2_Human1.61115702
17* HNF4A_19822575_ChIP-Seq_HepG2_Human1.53458501
18* ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.37701892
19ESR1_21235772_ChIP-Seq_MCF-7_Human1.36051142
20STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.34710861
21E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.34026453
22RARG_19884340_ChIP-ChIP_MEFs_Mouse1.32159340
23PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.24187569
24MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.23270064
25ESR2_21235772_ChIP-Seq_MCF-7_Human1.16419766
26RXRA_24833708_ChIP-Seq_LIVER_Mouse1.16234775
27TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.13893187
28SOX2_27498859_Chip-Seq_STOMACH_Mouse1.13775759
29ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.13206873
30GATA4_25053715_ChIP-Seq_YYC3_Human1.05208331
31IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.02519489
32NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.01404952
33HTT_18923047_ChIP-ChIP_STHdh_Human1.00920414
34GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.99985461
35PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.98611713
36THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.96857968
37STAT3_1855785_ChIP-Seq_MESCs_Mouse0.91622021
38CDX2_20551321_ChIP-Seq_CACO-2_Human0.88235388
39RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.84044885
40LXR_22292898_ChIP-Seq_THP-1_Human0.83740351
41GATA1_22025678_ChIP-Seq_K562_Human0.82220642
42AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.80625878
43AUTS2_25519132_ChIP-Seq_293T-REX_Human0.80103309
44SOX2_21211035_ChIP-Seq_LN229_Human0.79022272
45CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.77946366
46EGR1_19032775_ChIP-ChIP_M12_Human0.77391009
47RAD21_21589869_ChIP-Seq_MESCs_Mouse0.77091980
48BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.76621483
49HNFA_21074721_ChIP-Seq_CACO-2_Human0.73572200
50BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.73204801
51KAP1_22055183_ChIP-Seq_ESCs_Mouse0.73064820
52SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.72451107
53AR_21909140_ChIP-Seq_LNCAP_Human0.71824493
54SALL4_18804426_ChIP-ChIP_XEN_Mouse0.71636088
55NFE2_27457419_Chip-Seq_LIVER_Mouse0.70707187
56NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.69436756
57ESR1_15608294_ChIP-ChIP_MCF-7_Human0.68891396
58IRF8_22096565_ChIP-ChIP_GC-B_Human0.68152768
59IRF1_19129219_ChIP-ChIP_H3396_Human0.67889423
60Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.67561430
61PHF8_20622853_ChIP-Seq_HELA_Human0.67411477
62SRY_22984422_ChIP-ChIP_TESTIS_Rat0.66797810
63FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.66552913
64CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.66302210
65FOXO3_23340844_ChIP-Seq_DLD1_Human0.65895876
66MYC_19915707_ChIP-ChIP_AK7_Human0.65705857
67GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.65592715
68NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.65332656
69NRF2_20460467_ChIP-Seq_MEFs_Mouse0.65332656
70SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.65248082
71ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.64852862
72RARA_24833708_ChIP-Seq_LIVER_Mouse0.64338455
73TRIM28_21343339_ChIP-Seq_HEK293_Human0.63980248
74GATA6_25053715_ChIP-Seq_YYC3_Human0.63063630
75* RAC3_21632823_ChIP-Seq_H3396_Human0.62727796
76P53_21459846_ChIP-Seq_SAOS-2_Human0.62433753
77ZNF263_19887448_ChIP-Seq_K562_Human0.61933658
78BCAT_22108803_ChIP-Seq_LS180_Human0.61835145
79ERG_21242973_ChIP-ChIP_JURKAT_Human0.60164103
80FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.60147011
81ETV2_25802403_ChIP-Seq_MESCs_Mouse0.59978569
82TP53_18474530_ChIP-ChIP_U2OS_Human0.59650857
83ESET_19884257_ChIP-Seq_ESCs_Mouse0.58996303
84AR_20517297_ChIP-Seq_VCAP_Human0.58944246
85GATA6_21074721_ChIP-Seq_CACO-2_Human0.58724007
86CEBPB_22108803_ChIP-Seq_LS180_Human0.58683138
87TAF2_19829295_ChIP-Seq_ESCs_Human0.57471398
88NFYA_21822215_ChIP-Seq_K562_Human0.57310499
89ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.56934593
90RACK7_27058665_Chip-Seq_MCF-7_Human0.55606834
91CTCF_27219007_Chip-Seq_Bcells_Human0.55416784
92DNAJC2_21179169_ChIP-ChIP_NT2_Human0.55111462
93SMC4_20622854_ChIP-Seq_HELA_Human0.55099328
94SPI1_20517297_ChIP-Seq_HL60_Human0.55071285
95EZH2_27294783_Chip-Seq_NPCs_Mouse0.54081508
96E2F1_20622854_ChIP-Seq_HELA_Human0.53491891
97CBX2_22325352_ChIP-Seq_293T-Rex_Human0.53396700
98RARB_24833708_ChIP-Seq_LIVER_Mouse0.53083138
99FOXH1_21741376_ChIP-Seq_EPCs_Human0.52883779
100PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.52586022
101STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.52263426
102CTCF_20526341_ChIP-Seq_ESCs_Human0.51923007
103SA1_27219007_Chip-Seq_Bcells_Human0.51335112
104GATA3_21867929_ChIP-Seq_CD8_Mouse0.51109635
105SMAD2/3_21741376_ChIP-Seq_ESCs_Human0.50698384
106CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.50594176
107* SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.50537034
108CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.50327094
109POU5F1_16518401_ChIP-PET_MESCs_Mouse0.50110894
110* STAT1_17558387_ChIP-Seq_HELA_Human0.49617502
111SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.49612707
112GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.48856729
113SOX2_20726797_ChIP-Seq_SW620_Human0.48633940
114MYC_19829295_ChIP-Seq_ESCs_Human0.48563634
115FOXA1_25552417_ChIP-Seq_VCAP_Human0.47614874
116ESR1_20079471_ChIP-ChIP_T-47D_Human0.47534853
117SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.47419208
118FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.47221255
119EBNA1_20929547_Chip-Seq_RAJI-cells_Human0.47078033
120* P63_20808887_ChIP-Seq_KERATINOCYTES_Human0.46783624
121EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.45990377
122TET1_21451524_ChIP-Seq_MESCs_Mouse0.45773626
123PPAR_26484153_Chip-Seq_NCI-H1993_Human0.45693274
124CBP_21632823_ChIP-Seq_H3396_Human0.45259147
125FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.44997257
126GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.44517151
127STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.44296004
128PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.44295422
129TBX20_22080862_ChIP-Seq_HEART_Mouse0.44285763
130TBX20_22328084_ChIP-Seq_HEART_Mouse0.44285763
131GATA2_19941826_ChIP-Seq_K562_Human0.43733600
132ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.42516485
133CDX2_22108803_ChIP-Seq_LS180_Human0.41475370

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005360_urolithiasis8.68171510
2MP0002139_abnormal_hepatobiliary_system7.81836966
3MP0005085_abnormal_gallbladder_physiolo5.53205565
4MP0005365_abnormal_bile_salt5.36417988
5MP0008875_abnormal_xenobiotic_pharmacok4.63252556
6MP0005332_abnormal_amino_acid3.85535841
7MP0003806_abnormal_nucleotide_metabolis3.80606303
8MP0003195_calcinosis3.68742228
9MP0003252_abnormal_bile_duct3.61666118
10MP0004019_abnormal_vitamin_homeostasis3.21373802
11MP0010329_abnormal_lipoprotein_level2.91218798
12MP0002138_abnormal_hepatobiliary_system2.74791215
13MP0001666_abnormal_nutrient_absorption2.42952554
14MP0009840_abnormal_foam_cell2.32198788
15MP0009643_abnormal_urine_homeostasis2.29724788
16MP0003191_abnormal_cellular_cholesterol2.29529434
17MP0005083_abnormal_biliary_tract2.24666485
18MP0004043_abnormal_pH_regulation2.24525925
19MP0002118_abnormal_lipid_homeostasis1.84511340
20MP0005319_abnormal_enzyme/_coenzyme1.83867339
21MP0000609_abnormal_liver_physiology1.80205812
22MP0005636_abnormal_mineral_homeostasis1.73531148
23MP0005584_abnormal_enzyme/coenzyme_acti1.70177339
24MP0001764_abnormal_homeostasis1.62661085
25MP0001756_abnormal_urination1.59712252
26MP0003868_abnormal_feces_composition1.55141265
27MP0003186_abnormal_redox_activity1.47059593
28MP0001765_abnormal_ion_homeostasis1.34364677
29MP0002876_abnormal_thyroid_physiology1.33145095
30MP0002136_abnormal_kidney_physiology1.32573317
31MP0005451_abnormal_body_composition1.32353895
32MP0006036_abnormal_mitochondrial_physio1.02600967
33MP0000598_abnormal_liver_morphology1.01824197
34MP0005084_abnormal_gallbladder_morpholo1.00429937
35MP0005647_abnormal_sex_gland0.96274016
36MP0009764_decreased_sensitivity_to0.96016147
37MP0002132_abnormal_respiratory_system0.95461101
38MP0003705_abnormal_hypodermis_morpholog0.94150397
39MP0005535_abnormal_body_temperature0.92646381
40MP0001661_extended_life_span0.90264001
41MP0009642_abnormal_blood_homeostasis0.89339952
42MP0000604_amyloidosis0.87659641
43MP0005670_abnormal_white_adipose0.86628239
44MP0001915_intracranial_hemorrhage0.86382000
45MP0008469_abnormal_protein_level0.85463696
46MP0005058_abnormal_lysosome_morphology0.82790244
47MP0000538_abnormal_urinary_bladder0.80726065
48MP0009697_abnormal_copulation0.78937922
49MP0005187_abnormal_penis_morphology0.78348520
50MP0003656_abnormal_erythrocyte_physiolo0.77293798
51MP0003011_delayed_dark_adaptation0.76718492
52MP0002928_abnormal_bile_duct0.76128471
53MP0005220_abnormal_exocrine_pancreas0.74922728
54MP0009763_increased_sensitivity_to0.72592853
55MP0002078_abnormal_glucose_homeostasis0.72335888
56MP0003879_abnormal_hair_cell0.70163049
57MP0002254_reproductive_system_inflammat0.69927799
58MP0005408_hypopigmentation0.69620664
59MP0005376_homeostasis/metabolism_phenot0.68421051
60MP0003638_abnormal_response/metabolism_0.68129322
61MP0008961_abnormal_basal_metabolism0.67636345
62MP0005464_abnormal_platelet_physiology0.63885989
63MP0006035_abnormal_mitochondrial_morpho0.63713105
64MP0003329_amyloid_beta_deposits0.63189191
65MP0009765_abnormal_xenobiotic_induced0.63090650
66MP0005395_other_phenotype0.63037810
67MP0002282_abnormal_trachea_morphology0.62962101
68MP0002168_other_aberrant_phenotype0.62379648
69MP0000230_abnormal_systemic_arterial0.62210412
70MP0003878_abnormal_ear_physiology0.60724274
71MP0005377_hearing/vestibular/ear_phenot0.60724274
72MP0002249_abnormal_larynx_morphology0.56984275
73MP0002796_impaired_skin_barrier0.56013779
74MP0002135_abnormal_kidney_morphology0.55720431
75MP0010368_abnormal_lymphatic_system0.53974231
76MP0004264_abnormal_extraembryonic_tissu0.53866637
77MP0002971_abnormal_brown_adipose0.53629962
78MP0005666_abnormal_adipose_tissue0.53531413
79MP0005334_abnormal_fat_pad0.51813610
80MP0005266_abnormal_metabolism0.51799157
81MP0003690_abnormal_glial_cell0.50052889
82MP0004883_abnormal_blood_vessel0.48144862
83MP0003959_abnormal_lean_body0.46094076
84MP0003724_increased_susceptibility_to0.45447633
85MP0009053_abnormal_anal_canal0.44968637
86MP0005164_abnormal_response_to0.44741707
87MP0003300_gastrointestinal_ulcer0.43917400
88MP0004130_abnormal_muscle_cell0.43436465
89MP0003953_abnormal_hormone_level0.42999480
90MP0000249_abnormal_blood_vessel0.42867908
91MP0005023_abnormal_wound_healing0.42608627
92MP0001958_emphysema0.42494815
93MP0009785_altered_susceptibility_to0.42197445
94MP0003718_maternal_effect0.41128032
95MP0000566_synostosis0.41092553
96MP0005166_decreased_susceptibility_to0.38957011
97MP0003075_altered_response_to0.37595082
98MP0010234_abnormal_vibrissa_follicle0.36855126
99MP0004885_abnormal_endolymph0.35700608
100MP0008874_decreased_physiological_sensi0.35608083
101MP0009672_abnormal_birth_weight0.33703766
102MP0004147_increased_porphyrin_level0.32840706
103MP0006082_CNS_inflammation0.31232694
104MP0002837_dystrophic_cardiac_calcinosis0.30332142
105MP0008873_increased_physiological_sensi0.29403186
106MP0001986_abnormal_taste_sensitivity0.29023168
107MP0001845_abnormal_inflammatory_respons0.28372669
108MP0002090_abnormal_vision0.27979059
109MP0005448_abnormal_energy_balance0.27641028
110MP0004782_abnormal_surfactant_physiolog0.25903436
111MP0002089_abnormal_postnatal_growth/wei0.25850923
112MP0000639_abnormal_adrenal_gland0.25805428
113MP0008872_abnormal_physiological_respon0.25499034
114MP0009115_abnormal_fat_cell0.25389609
115MP0009384_cardiac_valve_regurgitation0.25313204
116MP0000467_abnormal_esophagus_morphology0.25111019
117MP0002896_abnormal_bone_mineralization0.24492436
118MP0005167_abnormal_blood-brain_barrier0.24335128
119MP0005197_abnormal_uvea_morphology0.24045347
120MP0002970_abnormal_white_adipose0.23559799
121MP0001851_eye_inflammation0.22452339
122MP0010386_abnormal_urinary_bladder0.20473957
123MP0005646_abnormal_pituitary_gland0.19615791
124MP0000920_abnormal_myelination0.18658854
125MP0003632_abnormal_nervous_system0.18311526

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of aromatic amino acid family metabolism (HP:0004338)6.11515328
2Intrahepatic cholestasis (HP:0001406)5.75162329
3Hyperglycinuria (HP:0003108)5.31233514
4Gout (HP:0001997)5.26232425
5Deep venous thrombosis (HP:0002625)5.22105878
6Abnormality of glutamine family amino acid metabolism (HP:0010902)5.16509779
7Abnormality of monocarboxylic acid metabolism (HP:0010996)4.95120510
8Glomerulonephritis (HP:0000099)4.93663540
9Xanthomatosis (HP:0000991)4.88872328
10Abnormality of serine family amino acid metabolism (HP:0010894)4.84850729
11Abnormality of glycine metabolism (HP:0010895)4.84850729
12Ketosis (HP:0001946)4.74231882
13Hyperglycinemia (HP:0002154)4.58615999
14Prolonged partial thromboplastin time (HP:0003645)4.41628043
15Hyperammonemia (HP:0001987)4.34720849
16Abnormality of aspartate family amino acid metabolism (HP:0010899)4.32769673
17Ketoacidosis (HP:0001993)4.25667126
18Hypobetalipoproteinemia (HP:0003563)4.23679619
19Abnormality of sulfur amino acid metabolism (HP:0004339)4.17703925
20Complement deficiency (HP:0004431)4.17421124
21Abnormality of purine metabolism (HP:0004352)4.16583371
22Increased purine levels (HP:0004368)4.00316656
23Hyperuricemia (HP:0002149)4.00316656
24Abnormality of fatty-acid metabolism (HP:0004359)3.95116801
25Recurrent gram-negative bacterial infections (HP:0005420)3.92754012
26Delayed CNS myelination (HP:0002188)3.88404708
27Hyperlipoproteinemia (HP:0010980)3.82411650
28Abnormality of nucleobase metabolism (HP:0010932)3.73983180
29Joint hemorrhage (HP:0005261)3.73263452
30Proximal tubulopathy (HP:0000114)3.70153977
31Nephritis (HP:0000123)3.68610112
32Hypokalemic alkalosis (HP:0001949)3.45813525
33Metabolic alkalosis (HP:0200114)3.44805873
34Hypomagnesemia (HP:0002917)3.44002179
35Fat malabsorption (HP:0002630)3.42526343
36Alkalosis (HP:0001948)3.39299529
37Hyperactive renin-angiotensin system (HP:0000841)3.38277110
38Increased circulating renin level (HP:0000848)3.37815405
39Hypoglycemic coma (HP:0001325)3.35533450
40Hypolipoproteinemia (HP:0010981)3.18471357
41Abnormality of the common coagulation pathway (HP:0010990)3.15325033
42Metabolic acidosis (HP:0001942)3.15021498
43Abnormal urine output (HP:0012590)3.13038275
44Abnormality of methionine metabolism (HP:0010901)3.09471383
45Hemorrhage of the eye (HP:0011885)3.05580512
46Dicarboxylic aciduria (HP:0003215)3.04920959
47Abnormality of dicarboxylic acid metabolism (HP:0010995)3.04920959
48Generalized aminoaciduria (HP:0002909)3.04792808
49Epidermoid cyst (HP:0200040)3.02175378
50Menorrhagia (HP:0000132)3.01258728
51Polyuria (HP:0000103)3.01222421
52Gingival bleeding (HP:0000225)2.98883776
53Abnormality of complement system (HP:0005339)2.96127079
54Abnormality of chloride homeostasis (HP:0011422)2.92545542
55Vascular calcification (HP:0004934)2.91777176
56Abnormality of serum amino acid levels (HP:0003112)2.91028002
57Abnormality of pyrimidine metabolism (HP:0004353)2.88782798
58Osteomalacia (HP:0002749)2.87376090
59Abnormality of the level of lipoprotein cholesterol (HP:0010979)2.87066770
60Abnormality of magnesium homeostasis (HP:0004921)2.87055713
61Lethargy (HP:0001254)2.84946744
62Abnormality of renal excretion (HP:0011036)2.82908828
63Hypoalphalipoproteinemia (HP:0003233)2.79732603
64Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.76206941
65Purpura (HP:0000979)2.72928846
66Malnutrition (HP:0004395)2.69988959
67Abnormality of the intrinsic pathway (HP:0010989)2.69722848
68Steatorrhea (HP:0002570)2.67409852
69Hepatocellular carcinoma (HP:0001402)2.66600805
70Conjugated hyperbilirubinemia (HP:0002908)2.62553850
71Vomiting (HP:0002013)2.62183663
72Abnormality of urine glucose concentration (HP:0011016)2.62099685
73Glycosuria (HP:0003076)2.62099685
74Hyperbilirubinemia (HP:0002904)2.61747526
75Cardiovascular calcification (HP:0011915)2.58443431
76Neonatal onset (HP:0003623)2.57708022
77Reduced antithrombin III activity (HP:0001976)2.56282363
78Abnormal gallbladder physiology (HP:0012438)2.54990204
79Cholecystitis (HP:0001082)2.54990204
80Enlarged kidneys (HP:0000105)2.53761335
81Thrombophlebitis (HP:0004418)2.52257733
82Hydroxyprolinuria (HP:0003080)2.51932639
83Abnormality of proline metabolism (HP:0010907)2.51932639
84Pulmonary embolism (HP:0002204)2.48488210
85Irritability (HP:0000737)2.45599487
86Tetany (HP:0001281)2.38262178
87Cerebral edema (HP:0002181)2.38104924
88Rickets (HP:0002748)2.37711744
89Abnormal drinking behavior (HP:0030082)2.37340702
90Polydipsia (HP:0001959)2.37340702
91Systemic lupus erythematosus (HP:0002725)2.35137735
92Nephrolithiasis (HP:0000787)2.34258623
93Spastic diplegia (HP:0001264)2.32956560
94Renal tubular acidosis (HP:0001947)2.32583009
95Sensorimotor neuropathy (HP:0007141)2.31255016
96Fair hair (HP:0002286)2.30751602
97Abnormality of the Achilles tendon (HP:0005109)2.29136439
98Renal salt wasting (HP:0000127)2.26621818
99Hypercholesterolemia (HP:0003124)2.23443804
100Late onset (HP:0003584)2.20859819
101Confusion (HP:0001289)2.20817088
102Abnormal enzyme/coenzyme activity (HP:0012379)2.17204353
103Hyperaldosteronism (HP:0000859)2.14778843
104Cholelithiasis (HP:0001081)2.14338640
105Arthropathy (HP:0003040)2.14135153
106Hyperphosphaturia (HP:0003109)2.12942750
107Myocardial infarction (HP:0001658)2.10456856
108Spontaneous abortion (HP:0005268)2.03532767
109Neonatal hypoglycemia (HP:0001998)2.03022188
110Abnormal gallbladder morphology (HP:0012437)2.02945067
111Pancreatitis (HP:0001733)2.01949671
112Mitral stenosis (HP:0001718)2.01823127
113Bifid scrotum (HP:0000048)2.01054122
114Abnormality of renin-angiotensin system (HP:0000847)2.00689049
115Abnormality of alkaline phosphatase activity (HP:0004379)1.97581499
116Gangrene (HP:0100758)1.97020710
117Elevated alkaline phosphatase (HP:0003155)1.95030650
118Hypophosphatemic rickets (HP:0004912)1.93756112
119Abnormality of vitamin metabolism (HP:0100508)1.93076235
120Nausea (HP:0002018)1.93054028
121Hypoglycemic seizures (HP:0002173)1.92054597
122Hypophosphatemia (HP:0002148)1.91283677
123Opisthotonus (HP:0002179)1.90597238
124Hypochromic microcytic anemia (HP:0004840)1.90048759
125Increased serum ferritin (HP:0003281)1.85761415
126Increased mean platelet volume (HP:0011877)1.78777981
127Poikilocytosis (HP:0004447)1.78186462
128Abnormal urine phosphate concentration (HP:0012599)1.77998726
129Atrioventricular block (HP:0001678)1.76415778
130Abnormality of iron homeostasis (HP:0011031)1.76348386
131Epistaxis (HP:0000421)1.73924538
132Abnormal biliary tract physiology (HP:0012439)1.69663908
133Bile duct proliferation (HP:0001408)1.69663908
134Joint swelling (HP:0001386)1.65929733
135Impaired platelet aggregation (HP:0003540)1.65820612
136Abnormal platelet function (HP:0011869)1.65820612
137Abnormal platelet volume (HP:0011876)1.61011714
138Abnormality of transition element cation homeostasis (HP:0011030)1.60699764
139Reticulocytosis (HP:0001923)1.58466965

Predicted kinase interactions (KEA)

RankGene SetZ-score
1WNK36.78261118
2BCKDK6.51845634
3OXSR14.59439056
4WNK44.40410328
5FGFR43.76017213
6ERN13.43761339
7SIK12.65439196
8STK38L2.35653963
9PRPF4B2.33909517
10PIK3CA2.24103366
11ERBB42.08211767
12MST1R1.96548689
13INSRR1.83135834
14NTRK31.78945656
15TAOK31.67847416
16PDK31.49444712
17PDK41.49444712
18MAPK111.49119652
19NEK11.47092485
20MAP2K41.46374589
21PINK11.45003283
22STK391.39728696
23SGK2231.39439919
24SGK4941.39439919
25TRIB31.34872938
26GRK61.25895051
27ABL21.17637087
28PTK61.15377379
29MAP3K71.14675885
30PIK3CG1.09687561
31CSF1R1.09389297
32LATS11.08478126
33SGK31.05756026
34PDK21.04356428
35PKN21.03321824
36SGK21.01710087
37TNK21.00626738
38MAP3K21.00306696
39EPHB10.95967519
40PRKG10.94604698
41JAK20.93651428
42TYK20.93616718
43DAPK20.91786982
44TIE10.91612470
45NLK0.89601673
46STK380.89337162
47PRKAA20.86201900
48GSK3A0.84129373
49CSNK1D0.83287747
50MAP3K30.81481023
51NEK90.81056068
52RET0.80212200
53FLT30.79455422
54MYLK0.79048542
55MAP3K140.78659366
56MAP3K120.78374555
57PRKCZ0.78132047
58PRKAA10.77024224
59DYRK1B0.76177987
60MET0.75641689
61TAOK20.74770701
62FRK0.74409929
63MAP2K30.74167860
64PTK20.70232418
65KDR0.69140928
66MUSK0.67610000
67MAP3K110.66786794
68PRKCB0.64888773
69STK160.64417490
70MAPK150.63993171
71ZAP700.61571874
72MAP3K10.61054533
73FGFR20.60914489
74CAMKK10.60897636
75ERBB20.60842910
76PDPK10.59616569
77PRKACG0.59467135
78RPS6KA30.58110833
79CAMKK20.57808984
80CDK40.57538193
81LRRK20.55984211
82TGFBR20.54204947
83MAPKAPK30.53903132
84WNK10.53605485
85MAPK120.53578605
86SCYL20.52367704
87MAPK40.51750541
88RIPK10.51237248
89MAP3K60.50418345
90TBK10.49512960
91PRKACB0.47787484
92IRAK30.46459142
93CSNK2A10.45335955
94JAK10.45252064
95CAMK2G0.45012207
96MAP3K50.44367233
97SRC0.43782069
98CSNK2A20.41020165
99PIM20.40998812
100MAP3K100.40261713
101BLK0.39658634
102MAP2K60.39578001
103CSNK1E0.39433924
104EIF2AK10.38146672
105EPHA40.37836339
106CDK60.37636200
107CSK0.36365086
108PDK10.35277920
109PAK30.32906336
110PRKCQ0.31623806
111IRAK20.30523215
112MAPK30.30507525
113MAP3K130.28702049
114CSNK1A10.28254834
115SGK10.27564321
116IGF1R0.26878630
117EPHA30.26668682
118FER0.25585884
119PRKCG0.25487016
120MTOR0.25282383
121CAMK40.24942521
122PRKCD0.24914137
123PRKCA0.24607919
124IRAK10.22546465
125PKN10.22134554
126MAP2K10.21250363
127BMX0.21196259
128EGFR0.19866699
129MAPK70.19718908
130FGFR30.17673875
131ICK0.16591467
132CSNK1G10.16165600
133PRKCH0.15762792
134PRKACA0.15331504
135MAP2K20.14807201
136CAMK1D0.14201753

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001203.90333680
2Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.23862195
3Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006303.11060293
4Nitrogen metabolism_Homo sapiens_hsa009102.97116893
5Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.91206085
6Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.84277015
7Tryptophan metabolism_Homo sapiens_hsa003802.83789512
8Butanoate metabolism_Homo sapiens_hsa006502.82750472
9Arginine biosynthesis_Homo sapiens_hsa002202.76123533
10Fatty acid degradation_Homo sapiens_hsa000712.56051820
11Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.53072582
12Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.47991862
132-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.45589867
14Peroxisome_Homo sapiens_hsa041462.42339135
15Propanoate metabolism_Homo sapiens_hsa006402.39333540
16Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.38145238
17Pentose and glucuronate interconversions_Homo sapiens_hsa000402.35382563
18Complement and coagulation cascades_Homo sapiens_hsa046102.10699866
19Cyanoamino acid metabolism_Homo sapiens_hsa004602.10070082
20Fatty acid metabolism_Homo sapiens_hsa012121.87482851
21beta-Alanine metabolism_Homo sapiens_hsa004101.85234639
22PPAR signaling pathway_Homo sapiens_hsa033201.79669177
23Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.75226730
24Pyruvate metabolism_Homo sapiens_hsa006201.71576566
25Histidine metabolism_Homo sapiens_hsa003401.65870074
26Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.65136425
27Selenocompound metabolism_Homo sapiens_hsa004501.61850226
28Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.60768786
29Chemical carcinogenesis_Homo sapiens_hsa052041.60651289
30Sulfur metabolism_Homo sapiens_hsa009201.59415062
31Steroid hormone biosynthesis_Homo sapiens_hsa001401.58485585
32Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.55647077
33* Bile secretion_Homo sapiens_hsa049761.55338764
34Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.54979710
35Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.52767727
36Drug metabolism - other enzymes_Homo sapiens_hsa009831.44119751
37Vitamin digestion and absorption_Homo sapiens_hsa049771.40796725
38Carbon metabolism_Homo sapiens_hsa012001.38800668
39Retinol metabolism_Homo sapiens_hsa008301.35840021
40Phenylalanine metabolism_Homo sapiens_hsa003601.32209451
41Biosynthesis of amino acids_Homo sapiens_hsa012301.30749028
42Cysteine and methionine metabolism_Homo sapiens_hsa002701.28712987
43Fatty acid elongation_Homo sapiens_hsa000621.22929657
44Tyrosine metabolism_Homo sapiens_hsa003501.22497727
45Starch and sucrose metabolism_Homo sapiens_hsa005001.21247409
46Folate biosynthesis_Homo sapiens_hsa007901.19790505
47Staphylococcus aureus infection_Homo sapiens_hsa051501.16335235
48Caffeine metabolism_Homo sapiens_hsa002321.15029739
49Arginine and proline metabolism_Homo sapiens_hsa003301.11161895
50Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.08072077
51Lysine degradation_Homo sapiens_hsa003101.04551174
52Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.04293480
53Glutathione metabolism_Homo sapiens_hsa004801.03223898
54Maturity onset diabetes of the young_Homo sapiens_hsa049500.94196052
55Sulfur relay system_Homo sapiens_hsa041220.90349479
56ABC transporters_Homo sapiens_hsa020100.89175113
57Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.84304130
58Steroid biosynthesis_Homo sapiens_hsa001000.79363330
59Fat digestion and absorption_Homo sapiens_hsa049750.76555845
60Vitamin B6 metabolism_Homo sapiens_hsa007500.76398125
61Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.74954802
62Glycerolipid metabolism_Homo sapiens_hsa005610.73136516
63Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.69785854
64Pentose phosphate pathway_Homo sapiens_hsa000300.61445995
65One carbon pool by folate_Homo sapiens_hsa006700.59510205
66Metabolic pathways_Homo sapiens_hsa011000.53165807
67Fructose and mannose metabolism_Homo sapiens_hsa000510.50938074
68Pertussis_Homo sapiens_hsa051330.33954284
69Prion diseases_Homo sapiens_hsa050200.24890375
70Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.23333703
71Galactose metabolism_Homo sapiens_hsa000520.20740251
72Fatty acid biosynthesis_Homo sapiens_hsa000610.19786326
73Protein digestion and absorption_Homo sapiens_hsa049740.18206983
74Insulin resistance_Homo sapiens_hsa049310.17739674
75Adipocytokine signaling pathway_Homo sapiens_hsa049200.15623505
76alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.12818024
77Systemic lupus erythematosus_Homo sapiens_hsa053220.09788067
78Other glycan degradation_Homo sapiens_hsa005110.09582265
79Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.09416574
80Renin-angiotensin system_Homo sapiens_hsa046140.08957350
81Mineral absorption_Homo sapiens_hsa049780.08372642
82Collecting duct acid secretion_Homo sapiens_hsa049660.06732496
83Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.05036066
84Glycosaminoglycan degradation_Homo sapiens_hsa005310.04201277
85Glucagon signaling pathway_Homo sapiens_hsa049220.02773131
86Glycerophospholipid metabolism_Homo sapiens_hsa005640.01891110
87Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.01663094
88Thyroid hormone synthesis_Homo sapiens_hsa049180.01466866
89Carbohydrate digestion and absorption_Homo sapiens_hsa049730.01165163
90Lysosome_Homo sapiens_hsa041420.00791538
91Central carbon metabolism in cancer_Homo sapiens_hsa05230-0.2536930
92Circadian rhythm_Homo sapiens_hsa04710-0.2223864
93N-Glycan biosynthesis_Homo sapiens_hsa00510-0.1999538
94Ovarian steroidogenesis_Homo sapiens_hsa04913-0.1815994
95Type II diabetes mellitus_Homo sapiens_hsa04930-0.1788637
96Sphingolipid metabolism_Homo sapiens_hsa00600-0.1737377
97Bladder cancer_Homo sapiens_hsa05219-0.1602085
98Insulin signaling pathway_Homo sapiens_hsa04910-0.1551761
99Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520-0.1546048
100Parkinsons disease_Homo sapiens_hsa05012-0.1545873
101Regulation of autophagy_Homo sapiens_hsa04140-0.1488665
102Hepatitis C_Homo sapiens_hsa05160-0.1299845
103Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604-0.1246250
104African trypanosomiasis_Homo sapiens_hsa05143-0.1203386
105Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961-0.0806427
106Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512-0.0750121
107Amoebiasis_Homo sapiens_hsa05146-0.0522864
108Oxidative phosphorylation_Homo sapiens_hsa00190-0.0388669
109Serotonergic synapse_Homo sapiens_hsa04726-0.0320018
110Linoleic acid metabolism_Homo sapiens_hsa00591-0.0196136
111Arachidonic acid metabolism_Homo sapiens_hsa00590-0.0115695
112AMPK signaling pathway_Homo sapiens_hsa04152-0.0086450

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