SLC23A3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1angiotensin maturation (GO:0002003)6.62236857
2lysine metabolic process (GO:0006553)6.36677410
3lysine catabolic process (GO:0006554)6.36677410
4drug transmembrane transport (GO:0006855)6.10148432
5epoxygenase P450 pathway (GO:0019373)6.05413956
6regulation of guanylate cyclase activity (GO:0031282)6.02372281
7homocysteine metabolic process (GO:0050667)5.72220713
8aminoglycoside antibiotic metabolic process (GO:0030647)5.61280062
9urate metabolic process (GO:0046415)5.56760458
10diol metabolic process (GO:0034311)5.39802037
11drug transport (GO:0015893)5.33572612
12regulation of protein glycosylation (GO:0060049)5.08501008
13organic cation transport (GO:0015695)5.05431709
14positive regulation of glycoprotein biosynthetic process (GO:0010560)5.02255051
15drug metabolic process (GO:0017144)5.01630486
16sphingoid metabolic process (GO:0046519)4.95734452
17regulation of bile acid biosynthetic process (GO:0070857)4.91358002
18cytidine metabolic process (GO:0046087)4.90932038
19cytidine catabolic process (GO:0006216)4.90932038
20cytidine deamination (GO:0009972)4.90932038
21sphingosine metabolic process (GO:0006670)4.83593165
22positive regulation of guanylate cyclase activity (GO:0031284)4.76920577
23vitamin D metabolic process (GO:0042359)4.66196085
24cysteine metabolic process (GO:0006534)4.61650015
25regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)4.52680630
26indolalkylamine catabolic process (GO:0046218)4.47831460
27tryptophan catabolic process (GO:0006569)4.47831460
28indole-containing compound catabolic process (GO:0042436)4.47831460
29renal absorption (GO:0070293)4.46031955
30excretion (GO:0007588)4.42512784
31diacylglycerol metabolic process (GO:0046339)4.41572611
32transepithelial transport (GO:0070633)4.39967938
33fat-soluble vitamin biosynthetic process (GO:0042362)4.36941474
34regulation of triglyceride catabolic process (GO:0010896)4.28277461
35galactose catabolic process (GO:0019388)4.25357397
36calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338)4.24365716
37sulfate transmembrane transport (GO:1902358)4.22342780
38short-chain fatty acid metabolic process (GO:0046459)4.19623110
39positive regulation of glycoprotein metabolic process (GO:1903020)4.18691929
40intestinal absorption (GO:0050892)4.15833983
41quinone biosynthetic process (GO:1901663)4.12511260
42tryptophan metabolic process (GO:0006568)4.11954739
43nonribosomal peptide biosynthetic process (GO:0019184)4.09250214
44response to phenylpropanoid (GO:0080184)4.09051452
45aspartate family amino acid catabolic process (GO:0009068)4.05784422
46pyrimidine ribonucleoside catabolic process (GO:0046133)4.04820133
47L-phenylalanine metabolic process (GO:0006558)4.03678396
48erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)4.03678396
49aromatic amino acid family catabolic process (GO:0009074)4.00546704
50drug catabolic process (GO:0042737)3.91764844
51flavonoid metabolic process (GO:0009812)3.91500968
52citrulline biosynthetic process (GO:0019240)3.88750095
53phosphate ion transport (GO:0006817)3.86844223
54cellular ketone body metabolic process (GO:0046950)3.86485634
55exogenous drug catabolic process (GO:0042738)3.85492235
56alkaloid metabolic process (GO:0009820)3.84900158
57kynurenine metabolic process (GO:0070189)3.83695413
58fucose catabolic process (GO:0019317)3.83368616
59L-fucose metabolic process (GO:0042354)3.83368616
60L-fucose catabolic process (GO:0042355)3.83368616
61response to parathyroid hormone (GO:0071107)3.81279720
62glutathione biosynthetic process (GO:0006750)3.80701361
63regulation of cGMP biosynthetic process (GO:0030826)3.79057400
64trivalent inorganic anion homeostasis (GO:0072506)3.78481960
65phosphate ion homeostasis (GO:0055062)3.78481960
66positive regulation of digestive system process (GO:0060456)3.76609883
672-oxoglutarate metabolic process (GO:0006103)3.76356615
68artery smooth muscle contraction (GO:0014824)3.74634483
69auditory receptor cell differentiation (GO:0042491)3.72815227
70fructose metabolic process (GO:0006000)3.69902326
71biotin metabolic process (GO:0006768)3.68760350
72vitamin transport (GO:0051180)3.66567284
73cobalamin metabolic process (GO:0009235)3.66534614
74superoxide anion generation (GO:0042554)3.63390675
75polyol transport (GO:0015791)3.59474847
76erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)3.59138414
77L-phenylalanine catabolic process (GO:0006559)3.59138414
78phosphate ion transmembrane transport (GO:0035435)3.57965701
79cellular glucuronidation (GO:0052695)3.55958665
80hormone catabolic process (GO:0042447)3.55919593
81lipoprotein transport (GO:0042953)3.55748639
82vitamin transmembrane transport (GO:0035461)3.54494327
83cellular response to vitamin D (GO:0071305)3.53439896
84negative regulation of keratinocyte proliferation (GO:0010839)3.52158371
85regulation of systemic arterial blood pressure mediated by a chemical signal (GO:0003044)3.50265285
86endocrine process (GO:0050886)3.50265285
87regulation of systemic arterial blood pressure by hormone (GO:0001990)3.50265285
88bile acid and bile salt transport (GO:0015721)3.49379462
89glyoxylate metabolic process (GO:0046487)3.49028689
90pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.48871129
91sulfate transport (GO:0008272)3.47451150
92vitamin biosynthetic process (GO:0009110)3.46779705
93uronic acid metabolic process (GO:0006063)3.45954464
94glucuronate metabolic process (GO:0019585)3.45954464
95base-excision repair, AP site formation (GO:0006285)3.42291858
96amino-acid betaine metabolic process (GO:0006577)3.39553738
97peptide hormone processing (GO:0016486)3.37419568
98sulfur compound transport (GO:0072348)3.33975159
99regulation of cGMP metabolic process (GO:0030823)3.33189219
100glycerol metabolic process (GO:0006071)3.27069914
101cellular carbohydrate catabolic process (GO:0044275)3.25846294
102virion attachment to host cell (GO:0019062)3.25465435
103adhesion of symbiont to host cell (GO:0044650)3.25465435
104glycosylceramide metabolic process (GO:0006677)3.25125163
105tonic smooth muscle contraction (GO:0014820)3.24523700
106cellular modified amino acid catabolic process (GO:0042219)3.20665418
107arginine metabolic process (GO:0006525)3.20632722
108ketone body metabolic process (GO:1902224)3.20464995
109heme transport (GO:0015886)3.20445496
110response to mercury ion (GO:0046689)3.20118878
111xenobiotic catabolic process (GO:0042178)3.18280028
112interferon-gamma secretion (GO:0072643)3.18036290
113indole-containing compound metabolic process (GO:0042430)3.16877212
114pyrimidine nucleotide catabolic process (GO:0006244)3.16815728
115positive regulation of neurotransmitter secretion (GO:0001956)3.13707481
116modified amino acid transport (GO:0072337)3.13664811
117positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc3.13344861
118digestion (GO:0007586)3.12975340
119carnitine metabolic process (GO:0009437)3.12696919
120regulation of systemic arterial blood pressure (GO:0003073)3.12358071
121ribosomal large subunit biogenesis (GO:0042273)3.11702406
122proline transport (GO:0015824)3.10773382
123inositol phosphate-mediated signaling (GO:0048016)3.09751083
124L-ascorbic acid metabolic process (GO:0019852)3.07360975
125fat-soluble vitamin metabolic process (GO:0006775)3.06988026
126regulation of hydrogen peroxide metabolic process (GO:0010310)3.06175797
127glycine transport (GO:0015816)3.06152117
128serine family amino acid catabolic process (GO:0009071)3.05725869
129NADH metabolic process (GO:0006734)3.04891687
130branched-chain amino acid metabolic process (GO:0009081)3.04541593
131purine ribonucleoside bisphosphate metabolic process (GO:0034035)3.04434270
1323-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)3.04434270
133carnitine transport (GO:0015879)3.02824302
134amino-acid betaine transport (GO:0015838)3.02824302
135proline metabolic process (GO:0006560)3.02435045
136quinone metabolic process (GO:1901661)3.01675916
137aromatic amino acid family metabolic process (GO:0009072)3.00405543
138acetyl-CoA metabolic process (GO:0006084)3.00322357
139peptide biosynthetic process (GO:0043043)3.00243769
140positive regulation of uterine smooth muscle contraction (GO:0070474)2.99255062
141surfactant homeostasis (GO:0043129)2.99155117
142fatty acid beta-oxidation (GO:0006635)2.98838436
143synaptic vesicle docking involved in exocytosis (GO:0016081)2.98707767
144cellular biogenic amine catabolic process (GO:0042402)2.97578496
145amine catabolic process (GO:0009310)2.97578496
146oxaloacetate metabolic process (GO:0006107)2.95371116
147phosphatidylserine acyl-chain remodeling (GO:0036150)2.94681240
148positive regulation of cGMP biosynthetic process (GO:0030828)2.89986088
149indolalkylamine metabolic process (GO:0006586)2.88548404
150coenzyme catabolic process (GO:0009109)2.87801256
151fatty acid oxidation (GO:0019395)2.87410194
152regulation of cellular extravasation (GO:0002691)2.87065501
153very-low-density lipoprotein particle assembly (GO:0034379)2.86678492
154glutathione derivative biosynthetic process (GO:1901687)2.85472191
155glutathione derivative metabolic process (GO:1901685)2.85472191
156negative regulation of tumor necrosis factor-mediated signaling pathway (GO:0010804)2.85224910
157peptide catabolic process (GO:0043171)2.85062217
158nucleobase catabolic process (GO:0046113)2.84778463
159ether lipid metabolic process (GO:0046485)2.84453471
160cellular response to gamma radiation (GO:0071480)2.84340038
161high-density lipoprotein particle remodeling (GO:0034375)2.83416994
162omega-hydroxylase P450 pathway (GO:0097267)2.80479021
163behavioral response to nicotine (GO:0035095)2.80366938
164renal system process involved in regulation of blood volume (GO:0001977)2.79694788
165receptor guanylyl cyclase signaling pathway (GO:0007168)2.77674325
166response to pheromone (GO:0019236)2.76576199
167vitamin catabolic process (GO:0009111)2.75510901
168fat-soluble vitamin catabolic process (GO:0042363)2.75510901
169photoreceptor cell maintenance (GO:0045494)2.75080788
170alditol metabolic process (GO:0019400)2.74018353
171bile acid metabolic process (GO:0008206)2.72063982
172phenol-containing compound catabolic process (GO:0019336)2.71931468
173positive regulation of fatty acid transport (GO:2000193)2.70101532
174regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.69216785
175phenylpropanoid metabolic process (GO:0009698)2.68544968
176phosphatidylinositol acyl-chain remodeling (GO:0036149)2.67504319
177positive regulation of icosanoid secretion (GO:0032305)2.66716524
178quaternary ammonium group transport (GO:0015697)2.64874902
179regulation of lipoprotein metabolic process (GO:0050746)2.63726047
180iron coordination entity transport (GO:1901678)2.63015690
181response to nitrosative stress (GO:0051409)2.59543439
182plasma lipoprotein particle assembly (GO:0034377)2.58768970
183phosphatidylcholine acyl-chain remodeling (GO:0036151)2.58404454

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human5.71890528
2TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse3.57221857
3GBX2_23144817_ChIP-Seq_PC3_Human3.31897379
4ESR1_17901129_ChIP-ChIP_LIVER_Mouse3.04784401
5HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.69485482
6ZNF274_21170338_ChIP-Seq_K562_Hela2.65138171
7IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.64664548
8VDR_22108803_ChIP-Seq_LS180_Human2.60919429
9PCGF2_27294783_Chip-Seq_ESCs_Mouse2.56362723
10RXR_22158963_ChIP-Seq_LIVER_Mouse2.54523199
11FLI1_27457419_Chip-Seq_LIVER_Mouse2.51256686
12EGR1_23403033_ChIP-Seq_LIVER_Mouse2.42422826
13CDX2_20551321_ChIP-Seq_CACO-2_Human2.25507097
14SUZ12_27294783_Chip-Seq_NPCs_Mouse2.24585948
15ESR1_21235772_ChIP-Seq_MCF-7_Human2.23612955
16PPARA_22158963_ChIP-Seq_LIVER_Mouse2.19563983
17* NFE2_27457419_Chip-Seq_LIVER_Mouse2.18031596
18PCGF2_27294783_Chip-Seq_NPCs_Mouse2.05230885
19EZH2_22144423_ChIP-Seq_EOC_Human2.04303081
20GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.01207987
21AR_21909140_ChIP-Seq_LNCAP_Human1.98209386
22GATA4_25053715_ChIP-Seq_YYC3_Human1.94678577
23IRF8_22096565_ChIP-ChIP_GC-B_Human1.92697874
24LXR_22158963_ChIP-Seq_LIVER_Mouse1.90299631
25* EZH2_27294783_Chip-Seq_NPCs_Mouse1.89198562
26IGF1R_20145208_ChIP-Seq_DFB_Human1.88815003
27BCAT_22108803_ChIP-Seq_LS180_Human1.82038697
28PIAS1_25552417_ChIP-Seq_VCAP_Human1.81587965
29STAT1_17558387_ChIP-Seq_HELA_Human1.80481007
30BMI1_23680149_ChIP-Seq_NPCS_Mouse1.75060293
31EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.71052373
32SOX2_27498859_Chip-Seq_STOMACH_Mouse1.69085374
33KAP1_22055183_ChIP-Seq_ESCs_Mouse1.65089069
34FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.60997722
35RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.59182446
36* P53_22387025_ChIP-Seq_ESCs_Mouse1.56750573
37* CRX_20693478_ChIP-Seq_RETINA_Mouse1.56303939
38BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.55481451
39SUZ12_18555785_Chip-Seq_ESCs_Mouse1.52161517
40* EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.51504633
41CDX2_19796622_ChIP-Seq_MESCs_Mouse1.51419637
42ETV2_25802403_ChIP-Seq_MESCs_Mouse1.50016348
43* SOX2_20726797_ChIP-Seq_SW620_Human1.49453512
44STAT3_18555785_Chip-Seq_ESCs_Mouse1.49269306
45KLF4_18555785_Chip-Seq_ESCs_Mouse1.49037859
46ER_23166858_ChIP-Seq_MCF-7_Human1.48571676
47GATA1_22025678_ChIP-Seq_K562_Human1.48479402
48* NMYC_18555785_Chip-Seq_ESCs_Mouse1.48327252
49P300_18555785_Chip-Seq_ESCs_Mouse1.47788915
50* ZFX_18555785_Chip-Seq_ESCs_Mouse1.47111946
51IRF1_19129219_ChIP-ChIP_H3396_Human1.47110568
52* OCT4_18555785_Chip-Seq_ESCs_Mouse1.45928141
53SOX2_18555785_Chip-Seq_ESCs_Mouse1.45295330
54ESRRB_18555785_Chip-Seq_ESCs_Mouse1.44974573
55FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.44300808
56CTCF_18555785_Chip-Seq_ESCs_Mouse1.44000452
57FOXM1_26456572_ChIP-Seq_MCF-7_Human1.42202096
58* RUNX1_27457419_Chip-Seq_LIVER_Mouse1.41829048
59P300_19829295_ChIP-Seq_ESCs_Human1.41721495
60CTBP1_25329375_ChIP-Seq_LNCAP_Human1.41390548
61* CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.41061561
62NR3C1_21868756_ChIP-Seq_MCF10A_Human1.41012851
63SMAD1_18555785_Chip-Seq_ESCs_Mouse1.39940125
64BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.39627042
65POU3F2_20337985_ChIP-ChIP_501MEL_Human1.38197101
66* SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.37333090
67AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.37095590
68NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.36986610
69ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.36782299
70CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.36290325
71* MYC_19829295_ChIP-Seq_ESCs_Human1.35005764
72* E2F1_18555785_Chip-Seq_ESCs_Mouse1.34994251
73STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.31913015
74NANOG_20526341_ChIP-Seq_ESCs_Human1.31561088
75SOX2_19829295_ChIP-Seq_ESCs_Human1.31213530
76NANOG_19829295_ChIP-Seq_ESCs_Human1.31213530
77* OCT4_21477851_ChIP-Seq_ESCs_Mouse1.31086198
78GATA6_25053715_ChIP-Seq_YYC3_Human1.30964087
79CMYC_18555785_Chip-Seq_ESCs_Mouse1.30824886
80NANOG_18555785_Chip-Seq_ESCs_Mouse1.30714490
81AR_20517297_ChIP-Seq_VCAP_Human1.27377024
82* EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.27328598
83TP53_22573176_ChIP-Seq_HFKS_Human1.27144493
84GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.26668356
85TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.26605792
86FOXA1_21572438_ChIP-Seq_LNCaP_Human1.26250450
87CDX2_22108803_ChIP-Seq_LS180_Human1.25615839
88* PU1_27457419_Chip-Seq_LIVER_Mouse1.24487490
89PBX1_22567123_ChIP-ChIP_OVCAR3_Human1.24183052
90TAL1_26923725_Chip-Seq_HPCs_Mouse1.23765473
91FOXA1_27270436_Chip-Seq_PROSTATE_Human1.23168719
92FOXA1_25329375_ChIP-Seq_VCAP_Human1.23168719
93PRDM14_20953172_ChIP-Seq_ESCs_Human1.22267395
94PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.21891683
95IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.21402437
96CBP_20019798_ChIP-Seq_JUKART_Human1.21402437
97STAT3_23295773_ChIP-Seq_U87_Human1.18875186
98ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.18819935
99EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.18604643
100CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.18172418
101ZFP57_27257070_Chip-Seq_ESCs_Mouse1.17506715
102TCF4_18268006_ChIP-ChIP_LS174T_Human1.16987995
103NCOR_22424771_ChIP-Seq_293T_Human1.16125233
104MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.15908099
105* TAF2_19829295_ChIP-Seq_ESCs_Human1.15530465
106TCF4_22108803_ChIP-Seq_LS180_Human1.15458668
107AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.13431734
108LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.12800489
109GATA3_21878914_ChIP-Seq_MCF-7_Human1.12388927
110NFYA_21822215_ChIP-Seq_K562_Human1.12100875
111HNF4A_19822575_ChIP-Seq_HepG2_Human1.11746656
112SMAD3_21741376_ChIP-Seq_HESCs_Human1.11056468
113AUTS2_25519132_ChIP-Seq_293T-REX_Human1.09225819
114CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07583894
115TCF4_23295773_ChIP-Seq_U87_Human1.07290662
116SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.06132147
117FOXA1_25552417_ChIP-Seq_VCAP_Human1.06043053
118SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.05121506
119CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.04868193
120KDM2B_26808549_Chip-Seq_REH_Human1.04231480
121E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.03958071
122FUS_26573619_Chip-Seq_HEK293_Human1.03459976
123GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human1.02692264
124P63_26484246_Chip-Seq_KERATINOCYTES_Human1.02582180
125AR_25329375_ChIP-Seq_VCAP_Human1.02373796
126UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.02130433
127PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.01654689
128ERA_21632823_ChIP-Seq_H3396_Human1.01261667
129SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.00501315
130SMAD4_21799915_ChIP-Seq_A2780_Human0.99859340
131RXR_22108803_ChIP-Seq_LS180_Human0.99833995
132CEBPB_22108803_ChIP-Seq_LS180_Human0.99658605
133PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.99625925
134PHF8_20622853_ChIP-Seq_HELA_Human0.99124586
135AHR_22903824_ChIP-Seq_MCF-7_Human0.99088146
136CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.98386412
137KLF5_20875108_ChIP-Seq_MESCs_Mouse0.98334402
138CSB_26484114_Chip-Seq_FIBROBLAST_Human0.98133397
139RNF2_27304074_Chip-Seq_NSC_Mouse0.98092613
140* P53_21459846_ChIP-Seq_SAOS-2_Human0.98074382
141OCT4_20526341_ChIP-Seq_ESCs_Human0.96235622
142CBP_21632823_ChIP-Seq_H3396_Human0.95194317
143FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.94900874
144ESET_19884257_ChIP-Seq_ESCs_Mouse0.94850388
145HOXB7_26014856_ChIP-Seq_BT474_Human0.94228472
146CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.94066074
147CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.93741117
148ETV1_20927104_ChIP-Seq_GIST48_Human0.93652368
149GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.93535581
150BP1_19119308_ChIP-ChIP_Hs578T_Human0.93412938
151MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.93404108
152SMAD4_21741376_ChIP-Seq_EPCs_Human0.92902101
153TP53_18474530_ChIP-ChIP_U2OS_Human0.92685038
154KLF5_25053715_ChIP-Seq_YYC3_Human0.92252273
155RUNX2_22187159_ChIP-Seq_PCA_Human0.92163789
156SUZ12_18692474_ChIP-Seq_MESCs_Mouse0.91481512
157GATA1_26923725_Chip-Seq_HPCs_Mouse0.90696478
158RBPJ_22232070_ChIP-Seq_NCS_Mouse0.90242383
159CTBP2_25329375_ChIP-Seq_LNCAP_Human0.89521951
160PPAR_26484153_Chip-Seq_NCI-H1993_Human0.88386826
161CJUN_26792858_Chip-Seq_BT549_Human0.88370581
162JARID2_20064375_ChIP-Seq_MESCs_Mouse0.87173570
163HNFA_21074721_ChIP-Seq_CACO-2_Human0.87171028
164SMAD4_21741376_ChIP-Seq_HESCs_Human0.87144561
165SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.86917175
166FOXA2_19822575_ChIP-Seq_HepG2_Human0.85488079
167GATA3_24758297_ChIP-Seq_MCF-7_Human0.85007988
168ARNT_22903824_ChIP-Seq_MCF-7_Human0.84723437
169SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.84098272

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005360_urolithiasis6.60301496
2MP0002138_abnormal_hepatobiliary_system5.56585685
3MP0004019_abnormal_vitamin_homeostasis4.60790539
4MP0008004_abnormal_stomach_pH4.60585934
5MP0004043_abnormal_pH_regulation3.79443154
6MP0002139_abnormal_hepatobiliary_system3.35589864
7MP0005365_abnormal_bile_salt3.06083428
8MP0003252_abnormal_bile_duct3.02129697
9MP0005085_abnormal_gallbladder_physiolo2.94948335
10MP0005451_abnormal_body_composition2.94669621
11MP0005332_abnormal_amino_acid2.92990645
12MP0003195_calcinosis2.81760764
13MP0003011_delayed_dark_adaptation2.62716430
14MP0009643_abnormal_urine_homeostasis2.57967664
15MP0003183_abnormal_peptide_metabolism2.52581841
16MP0003718_maternal_effect2.52340047
17MP0001765_abnormal_ion_homeostasis2.41466980
18MP0004264_abnormal_extraembryonic_tissu2.33339838
19MP0009840_abnormal_foam_cell2.24152276
20MP0001756_abnormal_urination2.20634044
21MP0000579_abnormal_nail_morphology2.20107215
22MP0003315_abnormal_perineum_morphology2.14397121
23MP0003646_muscle_fatigue2.13548654
24MP0002928_abnormal_bile_duct2.11640816
25MP0005636_abnormal_mineral_homeostasis2.10971746
26MP0005670_abnormal_white_adipose2.09289790
27MP0008875_abnormal_xenobiotic_pharmacok1.99359127
28MP0002136_abnormal_kidney_physiology1.93185223
29MP0001663_abnormal_digestive_system1.86810872
30MP0000538_abnormal_urinary_bladder1.85525500
31MP0009379_abnormal_foot_pigmentation1.73176191
32MP0000613_abnormal_salivary_gland1.70892800
33MP0010234_abnormal_vibrissa_follicle1.66371669
34MP0003300_gastrointestinal_ulcer1.63707834
35MP0005551_abnormal_eye_electrophysiolog1.62932479
36MP0003283_abnormal_digestive_organ1.61955312
37MP0005381_digestive/alimentary_phenotyp1.61917263
38MP0001666_abnormal_nutrient_absorption1.60387744
39MP0001501_abnormal_sleep_pattern1.49889465
40MP0002876_abnormal_thyroid_physiology1.49411404
41MP0002736_abnormal_nociception_after1.48948643
42MP0001986_abnormal_taste_sensitivity1.46749294
43MP0001873_stomach_inflammation1.46360081
44MP0005083_abnormal_biliary_tract1.45281017
45MP0000462_abnormal_digestive_system1.42278443
46MP0003787_abnormal_imprinting1.41602570
47MP0001348_abnormal_lacrimal_gland1.37578988
48MP0008872_abnormal_physiological_respon1.29441866
49MP0000015_abnormal_ear_pigmentation1.28916638
50MP0000427_abnormal_hair_cycle1.27371987
51MP0005174_abnormal_tail_pigmentation1.26808893
52MP0003866_abnormal_defecation1.26409344
53MP0001346_abnormal_lacrimal_gland1.26165614
54MP0009697_abnormal_copulation1.24230083
55MP0005448_abnormal_energy_balance1.23960032
56MP0001485_abnormal_pinna_reflex1.19552589
57MP0005395_other_phenotype1.17082406
58MP0005646_abnormal_pituitary_gland1.16397150
59MP0004484_altered_response_of1.15322726
60MP0005220_abnormal_exocrine_pancreas1.12980746
61MP0001664_abnormal_digestion1.12674383
62MP0002098_abnormal_vibrissa_morphology1.12544803
63MP0006036_abnormal_mitochondrial_physio1.11961826
64MP0001764_abnormal_homeostasis1.11769680
65MP0000013_abnormal_adipose_tissue1.10611284
66MP0005386_behavior/neurological_phenoty1.07369724
67MP0004924_abnormal_behavior1.07369724
68MP0008775_abnormal_heart_ventricle1.05500442
69MP0002796_impaired_skin_barrier1.00865438
70MP0006082_CNS_inflammation1.00452866
71MP0000372_irregular_coat_pigmentation0.99517639
72MP0010329_abnormal_lipoprotein_level0.98604006
73MP0002638_abnormal_pupillary_reflex0.97817851
74MP0010155_abnormal_intestine_physiology0.96157980
75MP0004142_abnormal_muscle_tone0.93447872
76MP0010386_abnormal_urinary_bladder0.93390954
77MP0000490_abnormal_crypts_of0.92273538
78MP0002102_abnormal_ear_morphology0.89971168
79MP0002653_abnormal_ependyma_morphology0.89408727
80MP0002735_abnormal_chemical_nociception0.89041437
81MP0005253_abnormal_eye_physiology0.88204384
82MP0001968_abnormal_touch/_nociception0.87621315
83MP0004885_abnormal_endolymph0.87116435
84MP0005084_abnormal_gallbladder_morpholo0.86791069
85MP0001529_abnormal_vocalization0.86647482
86MP0000566_synostosis0.84754478
87MP0005501_abnormal_skin_physiology0.84616594
88MP0001188_hyperpigmentation0.82033570
89MP0002971_abnormal_brown_adipose0.81859764
90MP0005408_hypopigmentation0.80957051
91MP0004147_increased_porphyrin_level0.79911390
92MP0003941_abnormal_skin_development0.78922293
93MP0005410_abnormal_fertilization0.78528497
94MP0000516_abnormal_urinary_system0.77933376
95MP0005367_renal/urinary_system_phenotyp0.77933376
96MP0005645_abnormal_hypothalamus_physiol0.77440411
97MP0003879_abnormal_hair_cell0.77291256
98MP0002163_abnormal_gland_morphology0.76723697
99MP0003868_abnormal_feces_composition0.76627227
100MP0006276_abnormal_autonomic_nervous0.75664729
101MP0002069_abnormal_eating/drinking_beha0.74641868
102MP0000230_abnormal_systemic_arterial0.73693427
103MP0001119_abnormal_female_reproductive0.72734775
104MP0008469_abnormal_protein_level0.71948314
105MP0005257_abnormal_intraocular_pressure0.71869983
106MP0002078_abnormal_glucose_homeostasis0.71355792
107MP0003186_abnormal_redox_activity0.71062303
108MP0002168_other_aberrant_phenotype0.70773299
109MP0009764_decreased_sensitivity_to0.70149909
110MP0001905_abnormal_dopamine_level0.69536220
111MP0000762_abnormal_tongue_morphology0.69506298
112MP0001845_abnormal_inflammatory_respons0.69487809
113MP0000609_abnormal_liver_physiology0.69144763
114MP0002933_joint_inflammation0.68977554
115MP0009115_abnormal_fat_cell0.68807957
116MP0005377_hearing/vestibular/ear_phenot0.66529876
117MP0003878_abnormal_ear_physiology0.66529876
118MP0002160_abnormal_reproductive_system0.66493459
119MP0001970_abnormal_pain_threshold0.65951506
120MP0001191_abnormal_skin_condition0.65705305
121MP0003453_abnormal_keratinocyte_physiol0.65546659
122MP0002837_dystrophic_cardiac_calcinosis0.64862240
123MP0002148_abnormal_hypersensitivity_rea0.64014940
124MP0003953_abnormal_hormone_level0.63978244
125MP0001958_emphysema0.63441204
126MP0010771_integument_phenotype0.61411945
127MP0002896_abnormal_bone_mineralization0.59353854
128MP0005075_abnormal_melanosome_morpholog0.58984866
129MP0005584_abnormal_enzyme/coenzyme_acti0.58535615
130MP0002557_abnormal_social/conspecific_i0.57911253
131MP0001324_abnormal_eye_pigmentation0.57863035
132MP0000470_abnormal_stomach_morphology0.57642945
133MP0009785_altered_susceptibility_to0.57495583
134MP0000026_abnormal_inner_ear0.57187987
135MP0000751_myopathy0.57179772
136MP0003191_abnormal_cellular_cholesterol0.56070364
137MP0002272_abnormal_nervous_system0.55572223
138MP0002118_abnormal_lipid_homeostasis0.52366475
139MP0001944_abnormal_pancreas_morphology0.51617568
140MP0005165_increased_susceptibility_to0.51288424
141MP0005319_abnormal_enzyme/_coenzyme0.50737681
142MP0003693_abnormal_embryo_hatching0.50656325
143MP0009642_abnormal_blood_homeostasis0.50505922
144MP0002132_abnormal_respiratory_system0.49704583
145MP0002135_abnormal_kidney_morphology0.49581658
146MP0000477_abnormal_intestine_morphology0.48097815
147MP0008961_abnormal_basal_metabolism0.47889256
148MP0005535_abnormal_body_temperature0.47428186
149MP0002089_abnormal_postnatal_growth/wei0.46049800
150MP0003699_abnormal_female_reproductive0.45815460

Predicted human phenotypes

RankGene SetZ-score
1Ventricular fibrillation (HP:0001663)6.09732548
2Metabolic alkalosis (HP:0200114)5.34210948
3Hyperactive renin-angiotensin system (HP:0000841)4.97146333
4Abnormality of chloride homeostasis (HP:0011422)4.90993737
5Polyuria (HP:0000103)4.80239422
6Gout (HP:0001997)4.73643636
7Hypomagnesemia (HP:0002917)4.71806546
8Abnormal urine output (HP:0012590)4.61754831
9Hypokalemic alkalosis (HP:0001949)4.58652726
10Increased circulating renin level (HP:0000848)4.51548219
11Proximal tubulopathy (HP:0000114)4.49701684
12Abnormality of renal excretion (HP:0011036)4.40644938
13Abnormality of glutamine family amino acid metabolism (HP:0010902)4.39298603
14Increased purine levels (HP:0004368)4.29073091
15Hyperuricemia (HP:0002149)4.29073091
16Hyperglycinuria (HP:0003108)4.21757859
17Tetany (HP:0001281)3.95445244
18Abnormality of magnesium homeostasis (HP:0004921)3.94390975
19Abnormality of glycine metabolism (HP:0010895)3.84497523
20Abnormality of serine family amino acid metabolism (HP:0010894)3.84497523
21Abnormality of purine metabolism (HP:0004352)3.62033829
22Polydipsia (HP:0001959)3.49748315
23Abnormal drinking behavior (HP:0030082)3.49748315
24Reticulocytopenia (HP:0001896)3.46700479
25Abnormal hemoglobin (HP:0011902)3.45327780
26Ketoacidosis (HP:0001993)3.45134114
27Chronic diarrhea (HP:0002028)3.41596400
28Abnormality of aspartate family amino acid metabolism (HP:0010899)3.32602725
29Confusion (HP:0001289)3.32337641
30Potter facies (HP:0002009)3.29415921
31Facial shape deformation (HP:0011334)3.29415921
32Decreased circulating renin level (HP:0003351)3.27086716
33Congenital sensorineural hearing impairment (HP:0008527)3.25118922
34Hyperglycinemia (HP:0002154)3.24393843
35Alkalosis (HP:0001948)3.22887492
36Abnormality of the vitamin B12 metabolism (HP:0004341)3.20501904
37Congenital stationary night blindness (HP:0007642)3.20103413
38Hyperaldosteronism (HP:0000859)3.17165074
39Abnormality of nucleobase metabolism (HP:0010932)3.12486064
40Abnormality of vitamin B metabolism (HP:0004340)3.08372529
41Glycosuria (HP:0003076)3.07001520
42Abnormality of urine glucose concentration (HP:0011016)3.07001520
43Hypercalciuria (HP:0002150)3.06984966
44Delayed epiphyseal ossification (HP:0002663)3.03027811
45Dehydration (HP:0001944)2.95859872
46Hypobetalipoproteinemia (HP:0003563)2.94916527
47Ketosis (HP:0001946)2.92733831
48Abnormality of renin-angiotensin system (HP:0000847)2.91014316
49Renal salt wasting (HP:0000127)2.88845953
50Chorioretinal atrophy (HP:0000533)2.88512998
51Renal tubular acidosis (HP:0001947)2.86592995
52Hyperphosphaturia (HP:0003109)2.82608601
53Generalized aminoaciduria (HP:0002909)2.82090084
54Hyperammonemia (HP:0001987)2.77910287
55Tubular atrophy (HP:0000092)2.69047602
56Pigmentary retinal degeneration (HP:0001146)2.68048328
57Ileus (HP:0002595)2.65871290
58Fetal akinesia sequence (HP:0001989)2.64297712
59Hypothermia (HP:0002045)2.62118184
60Pancreatic cysts (HP:0001737)2.61197085
61Abnormality of serum amino acid levels (HP:0003112)2.55320945
62Megaloblastic anemia (HP:0001889)2.53228384
63Lethargy (HP:0001254)2.52640195
64Dicarboxylic aciduria (HP:0003215)2.52588185
65Abnormality of dicarboxylic acid metabolism (HP:0010995)2.52588185
66Fatigue (HP:0012378)2.49393912
67Abnormal urine phosphate concentration (HP:0012599)2.49091504
68Abnormality of macular pigmentation (HP:0008002)2.47781255
69Abnormality of fatty-acid metabolism (HP:0004359)2.47460598
70Metabolic acidosis (HP:0001942)2.44859366
71Abnormality of the renal cortex (HP:0011035)2.44715382
72Macrocytic anemia (HP:0001972)2.42198494
73Abnormality of proline metabolism (HP:0010907)2.40886525
74Hydroxyprolinuria (HP:0003080)2.40886525
75Hypoalbuminemia (HP:0003073)2.39907222
76Abnormal albumin level (HP:0012116)2.39907222
77Hyperventilation (HP:0002883)2.39875361
78Pendular nystagmus (HP:0012043)2.38558825
79Abnormality of potassium homeostasis (HP:0011042)2.35847971
80Vascular calcification (HP:0004934)2.33986955
81Abnormality of sulfur amino acid metabolism (HP:0004339)2.31828491
82Nephrolithiasis (HP:0000787)2.29644003
83Enlarged epiphyses (HP:0010580)2.29615090
84Vomiting (HP:0002013)2.29279380
85Reduced antithrombin III activity (HP:0001976)2.27622587
86Malnutrition (HP:0004395)2.26689444
87Abnormality of vitamin metabolism (HP:0100508)2.25052789
88Delayed CNS myelination (HP:0002188)2.24579868
89Fat malabsorption (HP:0002630)2.24283333
90Attenuation of retinal blood vessels (HP:0007843)2.23958701
91Abnormality of the renal medulla (HP:0100957)2.22014434
92Methylmalonic aciduria (HP:0012120)2.20049503
93Cerebellar dysplasia (HP:0007033)2.19395738
94Acute encephalopathy (HP:0006846)2.18753230
95Rickets (HP:0002748)2.18711672
96Hypokalemia (HP:0002900)2.14832241
97Molar tooth sign on MRI (HP:0002419)2.13911654
98Abnormality of midbrain morphology (HP:0002418)2.13911654
99Abnormality of pyrimidine metabolism (HP:0004353)2.13390534
100Epidermoid cyst (HP:0200040)2.11418746
101Abnormality of renal resorption (HP:0011038)2.08070055
102Cardiovascular calcification (HP:0011915)2.07246752
103Abnormality of aromatic amino acid family metabolism (HP:0004338)2.07051968
104Renal tubular dysfunction (HP:0000124)2.05220765
105Abolished electroretinogram (ERG) (HP:0000550)2.04229375
106Nausea (HP:0002018)2.04000106
107Metaphyseal irregularity (HP:0003025)2.03747672
108Nephrocalcinosis (HP:0000121)2.03009033
109Recurrent gram-negative bacterial infections (HP:0005420)2.01633413
110Nephronophthisis (HP:0000090)2.01253772
111Xanthomatosis (HP:0000991)2.00121756
112Widely patent fontanelles and sutures (HP:0004492)1.99051411
113Male infertility (HP:0003251)1.96846519
114Chronic hepatic failure (HP:0100626)1.96661628
115Type II lissencephaly (HP:0007260)1.96656606
116Hypoplasia of the fovea (HP:0007750)1.96285017
117Aplasia/Hypoplasia of the fovea (HP:0008060)1.96285017
118Hypophosphatemia (HP:0002148)1.94805696
119Amelogenesis imperfecta (HP:0000705)1.94482845
120Amniotic constriction ring (HP:0009775)1.93872131
121Abnormality of placental membranes (HP:0011409)1.93872131
122Abnormal tarsal ossification (HP:0008369)1.93160702
123Ulnar claw (HP:0001178)1.93002769
124Distal lower limb muscle weakness (HP:0009053)1.90651607
125Abnormality of calcium-phosphate metabolism (HP:0100530)1.90276015
126Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.89837196
127Abnormality of alanine metabolism (HP:0010916)1.89837196
128Hyperalaninemia (HP:0003348)1.89837196
129Severe visual impairment (HP:0001141)1.89113705
130Hepatic necrosis (HP:0002605)1.88940911
131Posterior subcapsular cataract (HP:0007787)1.88917132
132Abnormal rod and cone electroretinograms (HP:0008323)1.86368993
133Hypophosphatemic rickets (HP:0004912)1.85097914
134Enlarged kidneys (HP:0000105)1.83921197
135Thin bony cortex (HP:0002753)1.82396882
136Hypokinesia (HP:0002375)1.81881760
137Mesomelia (HP:0003027)1.81105641
138Pancreatic fibrosis (HP:0100732)1.79100698
139True hermaphroditism (HP:0010459)1.76028225
140Disproportionate short-trunk short stature (HP:0003521)1.74304052

Predicted kinase interactions (KEA)

RankGene SetZ-score
1OXSR15.62136315
2WNK35.05376097
3CASK4.34078850
4ACVR1B4.30666714
5NME13.90587793
6WNK43.90418522
7PKN23.58621856
8STK38L3.34750045
9CDK192.72471813
10LMTK22.68578741
11ADRBK22.63739486
12DAPK22.52216147
13TAOK32.36418141
14MAP4K22.21984402
15TNIK2.14263013
16CCNB12.11512085
17LATS12.07924089
18FLT32.01579700
19IRAK31.92960103
20BMPR1B1.91192911
21STK391.91074594
22PRKCH1.80666603
23NUAK11.74673776
24TXK1.71185022
25MST1R1.64722918
26PIK3CG1.63901957
27TTK1.62998813
28MAP4K11.59573316
29ERBB41.59351047
30MST41.58803459
31PINK11.45441187
32TRIM281.41909490
33AKT31.39503898
34EPHA21.33697011
35PASK1.27758473
36MUSK1.25254820
37EPHA31.24777506
38CDK121.23642728
39MAP3K121.18673972
40STK381.16477976
41EEF2K1.15392403
42MAP3K61.11926258
43TYRO31.10768615
44FGFR21.10763044
45ZAK1.08111461
46NEK11.07466073
47GRK11.04701545
48PIK3CA1.04640249
49LATS21.02118647
50PAK31.01226976
51EPHA40.97546684
52STK110.96009517
53SGK2230.94207828
54SGK4940.94207828
55MAP2K60.92958005
56MET0.92306134
57MAPK130.91952467
58INSRR0.91674804
59PRKCE0.90923980
60BMPR20.88977718
61TLK10.85479129
62MAP2K40.82954332
63EPHB20.82080172
64BCKDK0.80384626
65TRPM70.79199098
66FRK0.77725186
67MAP3K20.77530018
68STK30.76138905
69MAPK110.75627596
70IKBKB0.75613548
71TNK20.74733026
72MAP3K40.73279783
73SGK20.69087095
74MAP3K80.67751822
75IRAK10.67282102
76MELK0.66616984
77MAP3K140.64499175
78PRKCQ0.62820865
79MAP3K70.62607116
80PDK30.61176962
81PDK40.61176962
82PRKCZ0.61173514
83MAP2K70.60566362
84NEK90.59032612
85FES0.58973980
86CAMK2D0.58969685
87BRD40.58017526
88PRKD30.57595010
89CAMKK10.57256611
90SGK10.54824426
91PDK20.52901721
92BCR0.50330495
93LCK0.48981853
94PHKG20.48299826
95PHKG10.48299826
96PBK0.47335114
97EPHB10.47249454
98FER0.46507072
99STK160.45983455
100RPS6KA40.45481677
101CDK80.45407299
102GRK60.44549984
103PRKCD0.44511940
104PRKACG0.44277287
105EIF2AK20.44187150
106PRKCG0.43756994
107MAP3K130.43460545
108PTK2B0.42941231
109PRKG20.41805058
110ITK0.41255818
111TIE10.40859298
112MAP2K20.40409974
113PDK10.39977060
114FGFR40.39397631
115CSNK1G10.39044317
116BRAF0.38845268
117PLK20.38697086
118MAP3K110.38416559
119MAP3K10.38350298
120AURKB0.36743144
121STK100.36272708
122WNK10.35734896
123ABL20.35656166
124JAK20.34842901
125NEK20.32439538
126EIF2AK30.32414203
127CAMK2A0.32296116
128IGF1R0.32209669
129CSNK1A1L0.32110094
130PRKCI0.30873109
131ERBB30.30759106
132NLK0.30616726
133SRC0.30183217
134GSK3A0.30172101
135PRKAA20.29677445
136CDC42BPA0.29331942
137PRKCA0.28732175
138RIPK10.28084170
139MYLK0.27764423
140CHUK0.27712864
141CSNK1G30.27261893
142SGK30.26933551
143RPS6KB20.26840299
144TEC0.26750380
145EIF2AK10.25420512
146AKT20.24287732
147PLK10.23958473
148MAPKAPK50.23777894
149ADRBK10.23120682
150CSNK1A10.22105519
151PRKAA10.21871848
152DAPK10.21603153
153CDK90.21350631
154ERBB20.21297783
155RET0.20538821
156PDPK10.20353637
157PRKACA0.19325734

Predicted pathways (KEGG)

RankGene SetZ-score
1Cyanoamino acid metabolism_Homo sapiens_hsa004603.85041686
2Fat digestion and absorption_Homo sapiens_hsa049753.45829300
3Vitamin digestion and absorption_Homo sapiens_hsa049773.27524229
4Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.07506791
5Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.81515547
6Caffeine metabolism_Homo sapiens_hsa002322.78200939
7Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.76605493
8Propanoate metabolism_Homo sapiens_hsa006402.63691851
9Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.55944883
10Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.53435937
11Butanoate metabolism_Homo sapiens_hsa006502.53334869
12Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.47055544
13Pentose and glucuronate interconversions_Homo sapiens_hsa000402.42101306
14Peroxisome_Homo sapiens_hsa041462.27831968
15Selenocompound metabolism_Homo sapiens_hsa004502.22665641
162-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.20470679
17Tryptophan metabolism_Homo sapiens_hsa003802.14231827
18Other glycan degradation_Homo sapiens_hsa005112.08206990
19Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.99735100
20Fatty acid degradation_Homo sapiens_hsa000711.92119097
21Pyruvate metabolism_Homo sapiens_hsa006201.90121535
22Bile secretion_Homo sapiens_hsa049761.85821717
23Maturity onset diabetes of the young_Homo sapiens_hsa049501.81127721
24Arginine biosynthesis_Homo sapiens_hsa002201.78467612
25Protein digestion and absorption_Homo sapiens_hsa049741.77870358
26Glutathione metabolism_Homo sapiens_hsa004801.76506501
27Vitamin B6 metabolism_Homo sapiens_hsa007501.65109510
28Nitrogen metabolism_Homo sapiens_hsa009101.63376899
29beta-Alanine metabolism_Homo sapiens_hsa004101.59652302
30Oxidative phosphorylation_Homo sapiens_hsa001901.57865923
31Starch and sucrose metabolism_Homo sapiens_hsa005001.56167294
32Ether lipid metabolism_Homo sapiens_hsa005651.55135424
33Collecting duct acid secretion_Homo sapiens_hsa049661.54127976
34Carbohydrate digestion and absorption_Homo sapiens_hsa049731.52745658
35Folate biosynthesis_Homo sapiens_hsa007901.45917584
36Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.40801779
37Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.28792873
38Pentose phosphate pathway_Homo sapiens_hsa000301.27566769
39Histidine metabolism_Homo sapiens_hsa003401.26650709
40Retinol metabolism_Homo sapiens_hsa008301.26237091
41Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.24428349
42Sphingolipid metabolism_Homo sapiens_hsa006001.23948934
43Arginine and proline metabolism_Homo sapiens_hsa003301.21323405
44Fatty acid metabolism_Homo sapiens_hsa012121.19128922
45Primary bile acid biosynthesis_Homo sapiens_hsa001201.18986291
46Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.18577827
47Galactose metabolism_Homo sapiens_hsa000521.15604987
48Mineral absorption_Homo sapiens_hsa049781.11816958
49Fructose and mannose metabolism_Homo sapiens_hsa000511.11502847
50Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.11284705
51Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.10391051
52Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.05284383
53Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.04010790
54Cysteine and methionine metabolism_Homo sapiens_hsa002701.02699402
55Carbon metabolism_Homo sapiens_hsa012001.01192184
56Parkinsons disease_Homo sapiens_hsa050120.97764401
57Phototransduction_Homo sapiens_hsa047440.97673725
58Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.97113114
59Intestinal immune network for IgA production_Homo sapiens_hsa046720.94978300
60Lysine degradation_Homo sapiens_hsa003100.94795316
61Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.94383195
62Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.91793045
63Sulfur relay system_Homo sapiens_hsa041220.88695179
64Arachidonic acid metabolism_Homo sapiens_hsa005900.84363963
65ABC transporters_Homo sapiens_hsa020100.84171935
66PPAR signaling pathway_Homo sapiens_hsa033200.83761868
67Chemical carcinogenesis_Homo sapiens_hsa052040.82932614
68Allograft rejection_Homo sapiens_hsa053300.82296263
69Asthma_Homo sapiens_hsa053100.81897332
70Inositol phosphate metabolism_Homo sapiens_hsa005620.79838236
71Glycerophospholipid metabolism_Homo sapiens_hsa005640.78458819
72Ribosome_Homo sapiens_hsa030100.77877081
73Metabolic pathways_Homo sapiens_hsa011000.75815615
74Autoimmune thyroid disease_Homo sapiens_hsa053200.75484774
75Sulfur metabolism_Homo sapiens_hsa009200.74981462
76Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.74462198
77Type I diabetes mellitus_Homo sapiens_hsa049400.73969183
78One carbon pool by folate_Homo sapiens_hsa006700.70906027
79Glycerolipid metabolism_Homo sapiens_hsa005610.70512596
80Alzheimers disease_Homo sapiens_hsa050100.68512375
81Gastric acid secretion_Homo sapiens_hsa049710.67668852
82Graft-versus-host disease_Homo sapiens_hsa053320.66043436
83Huntingtons disease_Homo sapiens_hsa050160.64104066
84Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.63442497
85Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.61178989
86Steroid hormone biosynthesis_Homo sapiens_hsa001400.60616807
87Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.60531680
88Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.60366825
89Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.59857119
90Biosynthesis of amino acids_Homo sapiens_hsa012300.59349802
91Staphylococcus aureus infection_Homo sapiens_hsa051500.57313895
92Thyroid hormone synthesis_Homo sapiens_hsa049180.57179149
93Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.55669604
94Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.54334513
95Ovarian steroidogenesis_Homo sapiens_hsa049130.52271013
96Renin-angiotensin system_Homo sapiens_hsa046140.52266151
97Phenylalanine metabolism_Homo sapiens_hsa003600.50383581
98Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.50080662
99Steroid biosynthesis_Homo sapiens_hsa001000.49875628
100alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.48571961
101Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.47786925
102RNA polymerase_Homo sapiens_hsa030200.47262867
103Dorso-ventral axis formation_Homo sapiens_hsa043200.46320145
104Vibrio cholerae infection_Homo sapiens_hsa051100.43037878
105Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.42777320
106Serotonergic synapse_Homo sapiens_hsa047260.38458423
107Fatty acid elongation_Homo sapiens_hsa000620.38294602
108Insulin secretion_Homo sapiens_hsa049110.37966384
109ECM-receptor interaction_Homo sapiens_hsa045120.37467233
110Drug metabolism - other enzymes_Homo sapiens_hsa009830.36925555
111Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.36780458
112Synaptic vesicle cycle_Homo sapiens_hsa047210.35289764
113Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.31988429
114Hepatitis C_Homo sapiens_hsa051600.31282783
115Insulin resistance_Homo sapiens_hsa049310.30816704
116Bladder cancer_Homo sapiens_hsa052190.29841828
117Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.29489660
118Complement and coagulation cascades_Homo sapiens_hsa046100.28570784
119Tight junction_Homo sapiens_hsa045300.28229534
120Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.25694737
121African trypanosomiasis_Homo sapiens_hsa051430.25592498
122Phosphatidylinositol signaling system_Homo sapiens_hsa040700.24576061
123Linoleic acid metabolism_Homo sapiens_hsa005910.21929732
124Vascular smooth muscle contraction_Homo sapiens_hsa042700.21539173
125Pancreatic secretion_Homo sapiens_hsa049720.20681026
126Fatty acid biosynthesis_Homo sapiens_hsa000610.20226898
127Tyrosine metabolism_Homo sapiens_hsa003500.19851384
128Regulation of autophagy_Homo sapiens_hsa041400.19420084
129Cocaine addiction_Homo sapiens_hsa050300.18380340
130N-Glycan biosynthesis_Homo sapiens_hsa005100.18006054
131Rheumatoid arthritis_Homo sapiens_hsa053230.17371332
132Hematopoietic cell lineage_Homo sapiens_hsa046400.17076575
133Glucagon signaling pathway_Homo sapiens_hsa049220.16136674
134Pertussis_Homo sapiens_hsa051330.15104854
135Leukocyte transendothelial migration_Homo sapiens_hsa046700.13609033
136Cardiac muscle contraction_Homo sapiens_hsa042600.13563529
137Purine metabolism_Homo sapiens_hsa002300.12029327
138Salivary secretion_Homo sapiens_hsa049700.10951661
139Fanconi anemia pathway_Homo sapiens_hsa034600.10718523

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