Rank | Gene Set | Z-score |
---|---|---|
1 | L-amino acid import (GO:0043092) | 5.64165397 |
2 | cellular potassium ion homeostasis (GO:0030007) | 5.53252635 |
3 | L-phenylalanine catabolic process (GO:0006559) | 5.51454977 |
4 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 5.51454977 |
5 | amino acid import (GO:0043090) | 5.37085298 |
6 | sodium ion export (GO:0071436) | 5.35925412 |
7 | gamma-aminobutyric acid transport (GO:0015812) | 5.24363206 |
8 | cell communication by electrical coupling (GO:0010644) | 5.04174925 |
9 | exogenous drug catabolic process (GO:0042738) | 4.98747425 |
10 | complement activation, alternative pathway (GO:0006957) | 4.93798293 |
11 | L-phenylalanine metabolic process (GO:0006558) | 4.90508684 |
12 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 4.90508684 |
13 | locomotory exploration behavior (GO:0035641) | 4.88415204 |
14 | drug catabolic process (GO:0042737) | 4.76055271 |
15 | negative regulation of astrocyte differentiation (GO:0048712) | 4.70952850 |
16 | alanine transport (GO:0032328) | 4.69466477 |
17 | neurotransmitter-gated ion channel clustering (GO:0072578) | 4.64062510 |
18 | glyoxylate metabolic process (GO:0046487) | 4.63689030 |
19 | C4-dicarboxylate transport (GO:0015740) | 4.58718291 |
20 | regulation of short-term neuronal synaptic plasticity (GO:0048172) | 4.55316217 |
21 | omega-hydroxylase P450 pathway (GO:0097267) | 4.52959717 |
22 | regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371) | 4.48952867 |
23 | regulation of protein activation cascade (GO:2000257) | 4.47273037 |
24 | epoxygenase P450 pathway (GO:0019373) | 4.46187379 |
25 | neurotransmitter uptake (GO:0001504) | 4.35033056 |
26 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 4.34021422 |
27 | regulation of fibrinolysis (GO:0051917) | 4.28180205 |
28 | regulation of complement activation (GO:0030449) | 4.20431969 |
29 | cellular sodium ion homeostasis (GO:0006883) | 4.15807432 |
30 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 4.11434791 |
31 | potassium ion import (GO:0010107) | 4.10778372 |
32 | negative regulation of fibrinolysis (GO:0051918) | 4.08505370 |
33 | axon ensheathment in central nervous system (GO:0032291) | 4.04222646 |
34 | central nervous system myelination (GO:0022010) | 4.04222646 |
35 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 3.96927800 |
36 | response to auditory stimulus (GO:0010996) | 3.92149154 |
37 | synaptic vesicle maturation (GO:0016188) | 3.89834575 |
38 | negative regulation of sodium ion transport (GO:0010766) | 3.87202882 |
39 | cell communication by electrical coupling involved in cardiac conduction (GO:0086064) | 3.87098169 |
40 | regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307) | 3.86406584 |
41 | synaptic vesicle exocytosis (GO:0016079) | 3.81212216 |
42 | negative regulation of sterol transport (GO:0032372) | 3.77902220 |
43 | negative regulation of cholesterol transport (GO:0032375) | 3.77902220 |
44 | neuron cell-cell adhesion (GO:0007158) | 3.77646697 |
45 | ethanol oxidation (GO:0006069) | 3.76772224 |
46 | regulation of beta-amyloid formation (GO:1902003) | 3.76172808 |
47 | glutamate secretion (GO:0014047) | 3.75221085 |
48 | low-density lipoprotein particle remodeling (GO:0034374) | 3.74672621 |
49 | potassium ion homeostasis (GO:0055075) | 3.74072878 |
50 | glutamate metabolic process (GO:0006536) | 3.73897321 |
51 | serine family amino acid catabolic process (GO:0009071) | 3.73774385 |
52 | positive regulation of excitatory postsynaptic membrane potential (GO:2000463) | 3.72638087 |
53 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 3.71155969 |
54 | vocalization behavior (GO:0071625) | 3.70623933 |
55 | atrial cardiac muscle cell action potential (GO:0086014) | 3.69101161 |
56 | proline transport (GO:0015824) | 3.59213790 |
57 | protein carboxylation (GO:0018214) | 3.58315992 |
58 | peptidyl-glutamic acid carboxylation (GO:0017187) | 3.58315992 |
59 | positive regulation of synaptic transmission, glutamatergic (GO:0051968) | 3.57889366 |
60 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 3.54477704 |
61 | adenine nucleotide transport (GO:0051503) | 3.54336170 |
62 | aromatic amino acid family catabolic process (GO:0009074) | 3.53454968 |
63 | ionotropic glutamate receptor signaling pathway (GO:0035235) | 3.50765951 |
64 | neurotransmitter secretion (GO:0007269) | 3.50482707 |
65 | regulation of respiratory gaseous exchange by neurological system process (GO:0002087) | 3.47146804 |
66 | regulation of neuronal synaptic plasticity (GO:0048168) | 3.46913915 |
67 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 3.44254360 |
68 | auditory behavior (GO:0031223) | 3.42711116 |
69 | chondroitin sulfate catabolic process (GO:0030207) | 3.42270205 |
70 | regulation of glutamate receptor signaling pathway (GO:1900449) | 3.39802453 |
71 | layer formation in cerebral cortex (GO:0021819) | 3.39556149 |
72 | regulation of astrocyte differentiation (GO:0048710) | 3.39147651 |
73 | cellular response to cholesterol (GO:0071397) | 3.37206999 |
74 | dicarboxylic acid biosynthetic process (GO:0043650) | 3.35406264 |
75 | drug metabolic process (GO:0017144) | 3.33759944 |
76 | urea metabolic process (GO:0019627) | 3.33274761 |
77 | glutamate receptor signaling pathway (GO:0007215) | 3.30953110 |
78 | bile acid biosynthetic process (GO:0006699) | 3.30800297 |
79 | regulation of cholesterol esterification (GO:0010872) | 3.30707650 |
80 | fibrinolysis (GO:0042730) | 3.30368674 |
81 | exploration behavior (GO:0035640) | 3.29568500 |
82 | acidic amino acid transport (GO:0015800) | 3.28223908 |
83 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 3.27896485 |
84 | blood coagulation, intrinsic pathway (GO:0007597) | 3.27071202 |
85 | L-serine transport (GO:0015825) | 3.25998054 |
86 | neuronal action potential propagation (GO:0019227) | 3.24176174 |
87 | regulation of long-term neuronal synaptic plasticity (GO:0048169) | 3.23596205 |
88 | regulation of synaptic vesicle exocytosis (GO:2000300) | 3.21286422 |
89 | postsynaptic membrane organization (GO:0001941) | 3.20545911 |
90 | positive regulation of cellular amide metabolic process (GO:0034250) | 3.20023693 |
91 | phospholipid efflux (GO:0033700) | 3.18987520 |
92 | protein localization to synapse (GO:0035418) | 3.16173785 |
93 | synaptic transmission, glutamatergic (GO:0035249) | 3.15235749 |
94 | reverse cholesterol transport (GO:0043691) | 3.14261683 |
95 | regulation of amyloid precursor protein catabolic process (GO:1902991) | 3.13934712 |
96 | presynaptic membrane organization (GO:0097090) | 3.12523734 |
97 | nitrogen cycle metabolic process (GO:0071941) | 3.12479865 |
98 | long-term synaptic potentiation (GO:0060291) | 3.11100269 |
99 | regulation of synapse structural plasticity (GO:0051823) | 3.09642133 |
100 | long-term memory (GO:0007616) | 3.09225048 |
101 | cerebellar granule cell differentiation (GO:0021707) | 3.07642708 |
102 | neurotransmitter transport (GO:0006836) | 3.07301468 |
103 | oxidative demethylation (GO:0070989) | 3.06465903 |
104 | neuronal ion channel clustering (GO:0045161) | 3.05031885 |
105 | regulation of triglyceride catabolic process (GO:0010896) | 3.03613842 |
106 | regulation of synaptic transmission, glutamatergic (GO:0051966) | 3.03585198 |
107 | protein-lipid complex remodeling (GO:0034368) | 3.00885386 |
108 | macromolecular complex remodeling (GO:0034367) | 3.00885386 |
109 | plasma lipoprotein particle remodeling (GO:0034369) | 3.00885386 |
110 | transmission of nerve impulse (GO:0019226) | 2.99259939 |
111 | bile acid metabolic process (GO:0008206) | 2.98513888 |
112 | negative regulation of smoothened signaling pathway (GO:0045879) | 2.98359800 |
113 | ovulation cycle (GO:0042698) | 2.97866803 |
114 | purine nucleotide transport (GO:0015865) | 2.97590013 |
115 | protein activation cascade (GO:0072376) | 2.96648209 |
116 | regulation of neurotransmitter levels (GO:0001505) | 2.96513487 |
117 | negative regulation of glial cell differentiation (GO:0045686) | 2.96243147 |
118 | high-density lipoprotein particle remodeling (GO:0034375) | 2.95321838 |
119 | cellular glucuronidation (GO:0052695) | 2.94927412 |
120 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 2.93590349 |
121 | acylglycerol homeostasis (GO:0055090) | 2.92107251 |
122 | triglyceride homeostasis (GO:0070328) | 2.92107251 |
123 | regulation of synaptic vesicle transport (GO:1902803) | 2.91269738 |
124 | L-glutamate transport (GO:0015813) | 2.90702950 |
125 | regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310) | 2.90001167 |
126 | response to mercury ion (GO:0046689) | 2.87984708 |
127 | positive regulation of potassium ion transmembrane transport (GO:1901381) | 2.87483038 |
128 | regulation of membrane repolarization (GO:0060306) | 2.87068565 |
129 | cellular response to sterol (GO:0036315) | 2.86569276 |
130 | cilium movement (GO:0003341) | 2.86287459 |
131 | negative regulation of lipase activity (GO:0060192) | 2.85748873 |
132 | negative regulation of hydrogen peroxide-induced cell death (GO:1903206) | 2.85601696 |
133 | regulation of respiratory system process (GO:0044065) | 2.84974717 |
134 | regulation of plasminogen activation (GO:0010755) | 2.84740787 |
135 | amino-acid betaine metabolic process (GO:0006577) | 2.84347078 |
136 | synaptic vesicle docking involved in exocytosis (GO:0016081) | 2.83685142 |
137 | ethanol metabolic process (GO:0006067) | 2.83196225 |
138 | presynaptic membrane assembly (GO:0097105) | 2.83019317 |
139 | complement activation (GO:0006956) | 2.80614786 |
140 | serine transport (GO:0032329) | 2.78766219 |
141 | regulation of glomerular filtration (GO:0003093) | 2.77642893 |
142 | regulation of synaptic plasticity (GO:0048167) | 2.75673014 |
143 | dermatan sulfate biosynthetic process (GO:0030208) | 2.74064843 |
144 | innervation (GO:0060384) | 2.73225843 |
145 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 2.72866079 |
146 | dermatan sulfate metabolic process (GO:0030205) | 2.68654537 |
147 | negative regulation of cytosolic calcium ion concentration (GO:0051481) | 2.66871082 |
148 | positive regulation of dendritic spine development (GO:0060999) | 2.66799416 |
149 | female mating behavior (GO:0060180) | 2.65826798 |
150 | membrane repolarization (GO:0086009) | 2.65141153 |
151 | oligodendrocyte differentiation (GO:0048709) | 2.64348944 |
152 | prepulse inhibition (GO:0060134) | 2.60932819 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 4.93172609 |
2 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 4.56326785 |
3 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 3.09615830 |
4 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.96888451 |
5 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.89815529 |
6 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 2.79253265 |
7 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.67064134 |
8 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.67064134 |
9 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.64479354 |
10 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.62554754 |
11 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.57244142 |
12 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.55493789 |
13 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 2.54827171 |
14 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.52609696 |
15 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 2.48972005 |
16 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 2.44960234 |
17 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.44416199 |
18 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 2.38457075 |
19 | AR_21572438_ChIP-Seq_LNCaP_Human | 2.34491258 |
20 | DROSHA_22980978_ChIP-Seq_HELA_Human | 2.32547517 |
21 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 2.29175693 |
22 | REST_21632747_ChIP-Seq_MESCs_Mouse | 2.25169388 |
23 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 2.18858381 |
24 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 2.17528173 |
25 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 2.16252125 |
26 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 2.14956370 |
27 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 2.00213164 |
28 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.98820372 |
29 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.95202390 |
30 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.89644396 |
31 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 1.84958574 |
32 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.72014616 |
33 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.68122264 |
34 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.67364028 |
35 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.65354154 |
36 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.62932788 |
37 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.59841202 |
38 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.59786205 |
39 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.56249734 |
40 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.54558204 |
41 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.54539533 |
42 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.50229342 |
43 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.47953995 |
44 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.47025662 |
45 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.44285597 |
46 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.42807771 |
47 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.39921928 |
48 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.38362379 |
49 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.36657803 |
50 | RXR_22108803_ChIP-Seq_LS180_Human | 1.34683472 |
51 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.32013816 |
52 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.30807315 |
53 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.29970312 |
54 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.29289852 |
55 | P300_19829295_ChIP-Seq_ESCs_Human | 1.28182731 |
56 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.25753288 |
57 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.24814339 |
58 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.24561212 |
59 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.20340754 |
60 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.20144443 |
61 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.19499813 |
62 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.19354538 |
63 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.19330637 |
64 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.19258198 |
65 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.18402328 |
66 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.18229457 |
67 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.18061145 |
68 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.17154131 |
69 | * AR_25329375_ChIP-Seq_VCAP_Human | 1.16304919 |
70 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.15894046 |
71 | TCF7L2_21901280_ChIP-Seq_H4IIE_Rat | 1.14857693 |
72 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.14706984 |
73 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.13506441 |
74 | SOX2_21211035_ChIP-Seq_LN229_Gbm | 1.12774747 |
75 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.12633318 |
76 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.12300067 |
77 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.12292477 |
78 | * AR_19668381_ChIP-Seq_PC3_Human | 1.10474701 |
79 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.10415784 |
80 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.09900741 |
81 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 1.09454361 |
82 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.08533948 |
83 | KDM2B_26808549_Chip-Seq_K562_Human | 1.07947383 |
84 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.07274431 |
85 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.05617421 |
86 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.05571942 |
87 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.05133495 |
88 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.04128686 |
89 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.03535749 |
90 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.03294100 |
91 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.02516216 |
92 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.01796655 |
93 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.01673184 |
94 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.01399678 |
95 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.01366099 |
96 | * STAT3_23295773_ChIP-Seq_U87_Human | 1.01100684 |
97 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 0.99591574 |
98 | SMC4_20622854_ChIP-Seq_HELA_Human | 0.99375123 |
99 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.98794525 |
100 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.97867567 |
101 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.97867567 |
102 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 0.97856420 |
103 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.97479768 |
104 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 0.96521703 |
105 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.96140149 |
106 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.95441203 |
107 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.93864554 |
108 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 0.93001833 |
109 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 0.92891186 |
110 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.92764666 |
111 | TP53_16413492_ChIP-PET_HCT116_Human | 0.92748834 |
112 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 0.92601613 |
113 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 0.91447024 |
114 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 0.91034872 |
115 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.90208105 |
116 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.89746019 |
117 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.89066747 |
118 | RUNX2_22187159_ChIP-Seq_PCA_Human | 0.88597831 |
119 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 0.88184472 |
120 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 0.87639182 |
121 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 0.85890963 |
122 | TCF4_23295773_ChIP-Seq_U87_Human | 0.85022936 |
123 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.84919208 |
124 | MYC_19915707_ChIP-ChIP_AK7_Human | 0.84826832 |
125 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.83824488 |
126 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 0.83538034 |
127 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.83420062 |
128 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.83315438 |
129 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.83247471 |
130 | * OCT4_19829295_ChIP-Seq_ESCs_Human | 0.82817390 |
131 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 0.82713183 |
132 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.80830331 |
133 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 0.80590239 |
134 | NEUROD2_26341353_ChIP-Seq_CORTEX_Mouse | 0.78943585 |
135 | KLF4_19829295_ChIP-Seq_ESCs_Human | 0.77864949 |
136 | HNF4A_19822575_ChIP-Seq_HepG2_Human | 0.75653318 |
137 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 0.74256894 |
138 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.74126668 |
139 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.73805768 |
140 | POU5F1_16518401_ChIP-PET_MESCs_Mouse | 0.72253528 |
141 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 0.70592515 |
142 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.69799271 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004859_abnormal_synaptic_plasticity | 4.56879518 |
2 | MP0002139_abnormal_hepatobiliary_system | 4.45644256 |
3 | MP0004858_abnormal_nervous_system | 3.63510128 |
4 | MP0003690_abnormal_glial_cell | 3.57007265 |
5 | MP0005646_abnormal_pituitary_gland | 3.47908905 |
6 | MP0005423_abnormal_somatic_nervous | 3.22089091 |
7 | MP0003635_abnormal_synaptic_transmissio | 3.14256758 |
8 | MP0003880_abnormal_central_pattern | 3.10395958 |
9 | MP0005365_abnormal_bile_salt | 2.99990782 |
10 | MP0005085_abnormal_gallbladder_physiolo | 2.95742383 |
11 | MP0008875_abnormal_xenobiotic_pharmacok | 2.93199253 |
12 | MP0003136_yellow_coat_color | 2.91827341 |
13 | MP0009780_abnormal_chondrocyte_physiolo | 2.80252909 |
14 | MP0004270_analgesia | 2.78399434 |
15 | MP0009745_abnormal_behavioral_response | 2.75305617 |
16 | MP0002064_seizures | 2.71891765 |
17 | MP0009046_muscle_twitch | 2.70809128 |
18 | MP0001486_abnormal_startle_reflex | 2.67877059 |
19 | MP0003329_amyloid_beta_deposits | 2.54455511 |
20 | MP0002063_abnormal_learning/memory/cond | 2.51857253 |
21 | MP0004885_abnormal_endolymph | 2.42506174 |
22 | MP0002572_abnormal_emotion/affect_behav | 2.32847188 |
23 | MP0001440_abnormal_grooming_behavior | 2.30342427 |
24 | MP0005360_urolithiasis | 2.30202155 |
25 | MP0001968_abnormal_touch/_nociception | 2.23722896 |
26 | MP0003195_calcinosis | 2.18716710 |
27 | MP0002272_abnormal_nervous_system | 2.04203369 |
28 | MP0002736_abnormal_nociception_after | 2.02669866 |
29 | MP0009384_cardiac_valve_regurgitation | 2.02064975 |
30 | MP0002734_abnormal_mechanical_nocicepti | 1.95433626 |
31 | MP0003634_abnormal_glial_cell | 1.93020780 |
32 | MP0001501_abnormal_sleep_pattern | 1.81046684 |
33 | MP0005167_abnormal_blood-brain_barrier | 1.80902965 |
34 | MP0008569_lethality_at_weaning | 1.80168151 |
35 | MP0003075_altered_response_to | 1.78696035 |
36 | MP0010329_abnormal_lipoprotein_level | 1.78463144 |
37 | MP0002254_reproductive_system_inflammat | 1.77783173 |
38 | MP0000778_abnormal_nervous_system | 1.77615197 |
39 | MP0002653_abnormal_ependyma_morphology | 1.75057778 |
40 | MP0001502_abnormal_circadian_rhythm | 1.72804297 |
41 | MP0002557_abnormal_social/conspecific_i | 1.72744894 |
42 | MP0005645_abnormal_hypothalamus_physiol | 1.71276135 |
43 | MP0003633_abnormal_nervous_system | 1.69729923 |
44 | MP0002733_abnormal_thermal_nociception | 1.68372783 |
45 | MP0001984_abnormal_olfaction | 1.66468098 |
46 | MP0002067_abnormal_sensory_capabilities | 1.66087737 |
47 | MP0003868_abnormal_feces_composition | 1.64765306 |
48 | MP0003252_abnormal_bile_duct | 1.62916863 |
49 | MP0001485_abnormal_pinna_reflex | 1.59676360 |
50 | MP0002638_abnormal_pupillary_reflex | 1.53966515 |
51 | MP0001970_abnormal_pain_threshold | 1.46834854 |
52 | MP0005332_abnormal_amino_acid | 1.36715711 |
53 | MP0003631_nervous_system_phenotype | 1.36247270 |
54 | MP0001666_abnormal_nutrient_absorption | 1.34650758 |
55 | MP0004142_abnormal_muscle_tone | 1.30598107 |
56 | MP0001986_abnormal_taste_sensitivity | 1.29151332 |
57 | MP0005386_behavior/neurological_phenoty | 1.27676254 |
58 | MP0004924_abnormal_behavior | 1.27676254 |
59 | MP0005551_abnormal_eye_electrophysiolog | 1.26954507 |
60 | MP0000604_amyloidosis | 1.26740752 |
61 | MP0002138_abnormal_hepatobiliary_system | 1.22638307 |
62 | MP0002735_abnormal_chemical_nociception | 1.21388761 |
63 | MP0002882_abnormal_neuron_morphology | 1.20453906 |
64 | MP0003183_abnormal_peptide_metabolism | 1.19504524 |
65 | MP0000955_abnormal_spinal_cord | 1.19382652 |
66 | MP0003191_abnormal_cellular_cholesterol | 1.19319863 |
67 | MP0002909_abnormal_adrenal_gland | 1.18928700 |
68 | MP0005670_abnormal_white_adipose | 1.16732350 |
69 | MP0005623_abnormal_meninges_morphology | 1.15266316 |
70 | MP0003279_aneurysm | 1.13862487 |
71 | MP0001905_abnormal_dopamine_level | 1.12206764 |
72 | MP0002152_abnormal_brain_morphology | 1.11790179 |
73 | MP0002876_abnormal_thyroid_physiology | 1.11410410 |
74 | MP0009840_abnormal_foam_cell | 1.11310694 |
75 | MP0003632_abnormal_nervous_system | 1.10734250 |
76 | MP0002089_abnormal_postnatal_growth/wei | 1.10703070 |
77 | MP0002066_abnormal_motor_capabilities/c | 1.10222484 |
78 | MP0008874_decreased_physiological_sensi | 1.09293448 |
79 | MP0003137_abnormal_impulse_conducting | 1.09240882 |
80 | MP0005377_hearing/vestibular/ear_phenot | 1.08709952 |
81 | MP0003878_abnormal_ear_physiology | 1.08709952 |
82 | MP0004215_abnormal_myocardial_fiber | 1.07892356 |
83 | MP0000920_abnormal_myelination | 1.06163057 |
84 | MP0003011_delayed_dark_adaptation | 1.05828940 |
85 | MP0002118_abnormal_lipid_homeostasis | 1.05092977 |
86 | MP0005253_abnormal_eye_physiology | 1.02409870 |
87 | MP0001963_abnormal_hearing_physiology | 1.02383172 |
88 | MP0001853_heart_inflammation | 1.00229353 |
89 | MP0002090_abnormal_vision | 0.99663160 |
90 | MP0005535_abnormal_body_temperature | 0.95252743 |
91 | MP0004742_abnormal_vestibular_system | 0.92058743 |
92 | MP0000631_abnormal_neuroendocrine_gland | 0.90560741 |
93 | MP0002229_neurodegeneration | 0.89147493 |
94 | MP0005379_endocrine/exocrine_gland_phen | 0.88994808 |
95 | MP0000026_abnormal_inner_ear | 0.88520274 |
96 | MP0004811_abnormal_neuron_physiology | 0.88455531 |
97 | MP0002184_abnormal_innervation | 0.88200874 |
98 | MP0000049_abnormal_middle_ear | 0.87507672 |
99 | MP0000566_synostosis | 0.83959829 |
100 | MP0006276_abnormal_autonomic_nervous | 0.82698798 |
101 | MP0003879_abnormal_hair_cell | 0.81933190 |
102 | MP0002249_abnormal_larynx_morphology | 0.78268791 |
103 | MP0000751_myopathy | 0.78208247 |
104 | MP0006072_abnormal_retinal_apoptosis | 0.75945741 |
105 | MP0003938_abnormal_ear_development | 0.75906443 |
106 | MP0005171_absent_coat_pigmentation | 0.74977432 |
107 | MP0002822_catalepsy | 0.73233927 |
108 | MP0005595_abnormal_vascular_smooth | 0.70089745 |
109 | MP0005166_decreased_susceptibility_to | 0.69814606 |
110 | MP0001299_abnormal_eye_distance/ | 0.69109735 |
111 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.67109653 |
112 | MP0002752_abnormal_somatic_nervous | 0.66990233 |
113 | MP0001177_atelectasis | 0.66260544 |
114 | MP0000428_abnormal_craniofacial_morphol | 0.64813677 |
115 | MP0002069_abnormal_eating/drinking_beha | 0.63892411 |
116 | MP0004130_abnormal_muscle_cell | 0.63636362 |
117 | MP0002971_abnormal_brown_adipose | 0.63396115 |
118 | MP0004019_abnormal_vitamin_homeostasis | 0.63368874 |
119 | MP0008872_abnormal_physiological_respon | 0.63334355 |
120 | MP0003172_abnormal_lysosome_physiology | 0.59861081 |
121 | MP0001943_abnormal_respiration | 0.57382715 |
122 | MP0005165_increased_susceptibility_to | 0.56321236 |
123 | MP0001529_abnormal_vocalization | 0.55031376 |
124 | MP0000609_abnormal_liver_physiology | 0.52917118 |
125 | MP0000639_abnormal_adrenal_gland | 0.52140997 |
126 | MP0000579_abnormal_nail_morphology | 0.51898135 |
127 | MP0001764_abnormal_homeostasis | 0.49335316 |
128 | MP0005448_abnormal_energy_balance | 0.46310301 |
129 | MP0005636_abnormal_mineral_homeostasis | 0.43356705 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Aplasia of the phalanges of the hand (HP:0009802) | 6.76960548 |
2 | Aplasia involving bones of the extremities (HP:0009825) | 6.76960548 |
3 | Aplasia involving bones of the upper limbs (HP:0009823) | 6.76960548 |
4 | Complement deficiency (HP:0004431) | 6.46935690 |
5 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 6.35663982 |
6 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 6.01890403 |
7 | Deep venous thrombosis (HP:0002625) | 5.74848563 |
8 | Megalencephaly (HP:0001355) | 5.34582665 |
9 | Prolonged partial thromboplastin time (HP:0003645) | 5.30415764 |
10 | Abnormality of complement system (HP:0005339) | 4.87083796 |
11 | Hypobetalipoproteinemia (HP:0003563) | 4.62895713 |
12 | Diplopia (HP:0000651) | 4.45173182 |
13 | Abnormality of binocular vision (HP:0011514) | 4.45173182 |
14 | Focal motor seizures (HP:0011153) | 4.41196351 |
15 | Neurofibrillary tangles (HP:0002185) | 4.31197938 |
16 | Hemiparesis (HP:0001269) | 4.30754125 |
17 | Systemic lupus erythematosus (HP:0002725) | 4.29659598 |
18 | Hemiplegia (HP:0002301) | 4.22731252 |
19 | Abnormal ciliary motility (HP:0012262) | 4.19594523 |
20 | Joint hemorrhage (HP:0005261) | 4.05138958 |
21 | Hyperlipoproteinemia (HP:0010980) | 4.03780182 |
22 | Abnormal respiratory motile cilium physiology (HP:0012261) | 3.94980166 |
23 | Myokymia (HP:0002411) | 3.89203236 |
24 | Glomerulonephritis (HP:0000099) | 3.88140576 |
25 | Epileptic encephalopathy (HP:0200134) | 3.43012164 |
26 | Spontaneous abortion (HP:0005268) | 3.38759053 |
27 | Hypoplastic left heart (HP:0004383) | 3.37873462 |
28 | Conjugated hyperbilirubinemia (HP:0002908) | 3.36743921 |
29 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 3.36450694 |
30 | Cerebral inclusion bodies (HP:0100314) | 3.31844602 |
31 | Xanthomatosis (HP:0000991) | 3.28987444 |
32 | Focal seizures (HP:0007359) | 3.19930820 |
33 | Supranuclear gaze palsy (HP:0000605) | 3.12440524 |
34 | Visual hallucinations (HP:0002367) | 3.09222453 |
35 | Intrahepatic cholestasis (HP:0001406) | 3.03933322 |
36 | Humeroradial synostosis (HP:0003041) | 3.03535397 |
37 | Synostosis involving the elbow (HP:0003938) | 3.03535397 |
38 | Progressive cerebellar ataxia (HP:0002073) | 2.98410106 |
39 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.94306137 |
40 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.94306137 |
41 | Torticollis (HP:0000473) | 2.90147910 |
42 | Rhinitis (HP:0012384) | 2.90138408 |
43 | Long nose (HP:0003189) | 2.90008871 |
44 | Generalized tonic-clonic seizures (HP:0002069) | 2.83318181 |
45 | Mixed hearing impairment (HP:0000410) | 2.83178435 |
46 | Abnormality of secondary sexual hair (HP:0009888) | 2.80292323 |
47 | Abnormality of the axillary hair (HP:0100134) | 2.80292323 |
48 | Short middle phalanx of the 5th finger (HP:0004220) | 2.80253729 |
49 | Action tremor (HP:0002345) | 2.80064797 |
50 | Split foot (HP:0001839) | 2.76819382 |
51 | Hypolipoproteinemia (HP:0010981) | 2.76650030 |
52 | Narrow nasal bridge (HP:0000446) | 2.73937471 |
53 | Abnormality of the common coagulation pathway (HP:0010990) | 2.73029421 |
54 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.72962510 |
55 | Absent/shortened dynein arms (HP:0200106) | 2.72962510 |
56 | Dysdiadochokinesis (HP:0002075) | 2.71091282 |
57 | Tetraparesis (HP:0002273) | 2.69835608 |
58 | Abnormality of the dental pulp (HP:0006479) | 2.67993489 |
59 | Postural instability (HP:0002172) | 2.65787721 |
60 | Spastic gait (HP:0002064) | 2.64218003 |
61 | Nephritis (HP:0000123) | 2.58755274 |
62 | Broad alveolar ridges (HP:0000187) | 2.56811085 |
63 | Clumsiness (HP:0002312) | 2.56714282 |
64 | Hypoplastic heart (HP:0001961) | 2.53835477 |
65 | Abnormal eating behavior (HP:0100738) | 2.50464007 |
66 | Short hallux (HP:0010109) | 2.49618890 |
67 | Abnormality of the intrinsic pathway (HP:0010989) | 2.48154731 |
68 | Maternal diabetes (HP:0009800) | 2.47229748 |
69 | Median cleft lip (HP:0000161) | 2.45262669 |
70 | Focal dystonia (HP:0004373) | 2.44524391 |
71 | Abnormality of permanent molar morphology (HP:0011071) | 2.41228379 |
72 | Abnormality of the dental root (HP:0006486) | 2.41228379 |
73 | Taurodontia (HP:0000679) | 2.41228379 |
74 | Abnormality of glycine metabolism (HP:0010895) | 2.37985084 |
75 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.37985084 |
76 | Abnormality of the level of lipoprotein cholesterol (HP:0010979) | 2.34923647 |
77 | Craniofacial dystonia (HP:0012179) | 2.33906961 |
78 | Confusion (HP:0001289) | 2.32957871 |
79 | Dry hair (HP:0011359) | 2.32915344 |
80 | Aplasia/Hypoplasia of the hallux (HP:0008362) | 2.32462967 |
81 | Hyperglycinemia (HP:0002154) | 2.30101446 |
82 | Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161) | 2.30041859 |
83 | Hypoalphalipoproteinemia (HP:0003233) | 2.29840022 |
84 | Clonus (HP:0002169) | 2.28138299 |
85 | Status epilepticus (HP:0002133) | 2.27989935 |
86 | Papilledema (HP:0001085) | 2.27694574 |
87 | Hyperglycinuria (HP:0003108) | 2.26274376 |
88 | Cerebral hypomyelination (HP:0006808) | 2.25605844 |
89 | Abnormality of molar (HP:0011077) | 2.24420980 |
90 | Abnormality of molar morphology (HP:0011070) | 2.24420980 |
91 | Delusions (HP:0000746) | 2.23832869 |
92 | Depression (HP:0000716) | 2.17832924 |
93 | Obstructive sleep apnea (HP:0002870) | 2.17519707 |
94 | Mutism (HP:0002300) | 2.16027690 |
95 | Urinary bladder sphincter dysfunction (HP:0002839) | 2.16026198 |
96 | Truncal ataxia (HP:0002078) | 2.14161491 |
97 | Abnormality of the middle phalanges of the toes (HP:0010183) | 2.13932440 |
98 | Scanning speech (HP:0002168) | 2.12188635 |
99 | Neonatal short-limb short stature (HP:0008921) | 2.10228427 |
100 | Back pain (HP:0003418) | 2.09503721 |
101 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 2.08897741 |
102 | Delayed CNS myelination (HP:0002188) | 2.07958511 |
103 | Atrioventricular block (HP:0001678) | 2.07797314 |
104 | Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376) | 2.06538775 |
105 | Bronchomalacia (HP:0002780) | 2.06092315 |
106 | Paraparesis (HP:0002385) | 2.05276106 |
107 | Adactyly (HP:0009776) | 2.04928718 |
108 | Epileptiform EEG discharges (HP:0011182) | 2.03743992 |
109 | Fat malabsorption (HP:0002630) | 2.03565040 |
110 | Abnormality of the periventricular white matter (HP:0002518) | 2.03164301 |
111 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 2.02139987 |
112 | Absence seizures (HP:0002121) | 2.00133377 |
113 | Mitral stenosis (HP:0001718) | 1.99920075 |
114 | Akinesia (HP:0002304) | 1.99675514 |
115 | Abnormality of pyrimidine metabolism (HP:0004353) | 1.99306014 |
116 | Dialeptic seizures (HP:0011146) | 1.98508320 |
117 | Dysmetria (HP:0001310) | 1.98490967 |
118 | Irritability (HP:0000737) | 1.98275870 |
119 | Tetraplegia (HP:0002445) | 1.95657950 |
120 | Abnormal gallbladder physiology (HP:0012438) | 1.94813809 |
121 | Cholecystitis (HP:0001082) | 1.94813809 |
122 | Annular pancreas (HP:0001734) | 1.94469582 |
123 | Retinal atrophy (HP:0001105) | 1.93932640 |
124 | Anxiety (HP:0000739) | 1.93795247 |
125 | Atonic seizures (HP:0010819) | 1.93733233 |
126 | Spastic tetraparesis (HP:0001285) | 1.93580841 |
127 | Fibular aplasia (HP:0002990) | 1.91312362 |
128 | Febrile seizures (HP:0002373) | 1.91121861 |
129 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 1.90262535 |
130 | Limb dystonia (HP:0002451) | 1.89825380 |
131 | Intention tremor (HP:0002080) | 1.88914122 |
132 | Neuronal loss in central nervous system (HP:0002529) | 1.88532087 |
133 | Recurrent gram-negative bacterial infections (HP:0005420) | 1.87868698 |
134 | Abnormal atrioventricular conduction (HP:0005150) | 1.86637665 |
135 | Lower limb muscle weakness (HP:0007340) | 1.85909844 |
136 | Hyperammonemia (HP:0001987) | 1.85775444 |
137 | Hypercholesterolemia (HP:0003124) | 1.85521420 |
138 | Poor eye contact (HP:0000817) | 1.83613438 |
139 | Urinary urgency (HP:0000012) | 1.83537754 |
140 | Ankle clonus (HP:0011448) | 1.82764804 |
141 | Heart block (HP:0012722) | 1.81638042 |
142 | Morphological abnormality of the pyramidal tract (HP:0002062) | 1.81473977 |
143 | Oligodactyly (hands) (HP:0001180) | 1.79832749 |
144 | Polyphagia (HP:0002591) | 1.79758955 |
145 | Rigidity (HP:0002063) | 1.78321324 |
146 | Peripheral hypomyelination (HP:0007182) | 1.76355181 |
147 | Bradykinesia (HP:0002067) | 1.73945293 |
148 | Aplasia/Hypoplasia of the 5th finger (HP:0006262) | 1.72149629 |
149 | Increased circulating renin level (HP:0000848) | 1.70935874 |
150 | Cutaneous syndactyly (HP:0012725) | 1.70354883 |
151 | Microglossia (HP:0000171) | 1.69682698 |
152 | Hyperventilation (HP:0002883) | 1.69256594 |
153 | Metabolic alkalosis (HP:0200114) | 1.68690411 |
154 | Selective tooth agenesis (HP:0001592) | 1.68561909 |
155 | Athetosis (HP:0002305) | 1.67860226 |
156 | Hypoplastic pelvis (HP:0008839) | 1.65257519 |
157 | Abnormality of chromosome segregation (HP:0002916) | 1.63941882 |
158 | Impaired vibration sensation in the lower limbs (HP:0002166) | 1.63797721 |
159 | Facial shape deformation (HP:0011334) | 1.63445941 |
160 | Potter facies (HP:0002009) | 1.63445941 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EPHA4 | 4.06370250 |
2 | NTRK2 | 3.78552611 |
3 | LMTK2 | 3.64899645 |
4 | TNIK | 3.17765005 |
5 | NTRK3 | 3.10661284 |
6 | PHKG2 | 2.87137331 |
7 | PHKG1 | 2.87137331 |
8 | PRKD3 | 2.27463744 |
9 | MAP3K9 | 2.16159895 |
10 | MARK1 | 2.03461066 |
11 | CASK | 1.97883914 |
12 | PAK6 | 1.97704615 |
13 | MUSK | 1.96537835 |
14 | MINK1 | 1.89394276 |
15 | MAP3K4 | 1.74358340 |
16 | PRKCG | 1.68636554 |
17 | MAP2K7 | 1.66843193 |
18 | MAPK13 | 1.66446904 |
19 | RIPK1 | 1.66295140 |
20 | DAPK2 | 1.60634396 |
21 | MAPK12 | 1.52414115 |
22 | NEK6 | 1.50767760 |
23 | TYRO3 | 1.50625103 |
24 | CAMKK1 | 1.44845440 |
25 | NTRK1 | 1.43796760 |
26 | TRIB3 | 1.38512781 |
27 | CDK5 | 1.37289186 |
28 | PDK2 | 1.36351206 |
29 | SGK223 | 1.30345192 |
30 | SGK494 | 1.30345192 |
31 | SGK2 | 1.28123174 |
32 | FES | 1.26147310 |
33 | PNCK | 1.20790667 |
34 | MAPK7 | 1.16696529 |
35 | SIK1 | 1.11977524 |
36 | PINK1 | 1.11726379 |
37 | KSR2 | 1.08539676 |
38 | SGK3 | 1.07849934 |
39 | FGR | 1.07280225 |
40 | GRK5 | 1.05036507 |
41 | DYRK1A | 1.02850001 |
42 | CAMK1G | 1.02819033 |
43 | PAK3 | 1.02408416 |
44 | LATS2 | 0.99181622 |
45 | CAMK2A | 0.92864763 |
46 | PRKCH | 0.91431028 |
47 | STK38 | 0.90892936 |
48 | PRKCE | 0.89873970 |
49 | ROCK2 | 0.89668979 |
50 | CDK15 | 0.88690399 |
51 | PLK2 | 0.87618076 |
52 | UHMK1 | 0.87171582 |
53 | ROCK1 | 0.87166539 |
54 | RIPK4 | 0.86682124 |
55 | DAPK1 | 0.85557005 |
56 | CDK18 | 0.84878071 |
57 | MARK2 | 0.83378329 |
58 | SIK2 | 0.83063580 |
59 | BRSK1 | 0.82252868 |
60 | KSR1 | 0.80276321 |
61 | MAPK15 | 0.80028514 |
62 | CDK11A | 0.75844430 |
63 | MAP2K4 | 0.75686489 |
64 | CDK14 | 0.74345476 |
65 | BMX | 0.74186545 |
66 | ADRBK1 | 0.72632756 |
67 | TNK2 | 0.70662224 |
68 | PRPF4B | 0.69729909 |
69 | SGK1 | 0.66985162 |
70 | MAP3K2 | 0.66902588 |
71 | CDC42BPA | 0.66164267 |
72 | CAMK2G | 0.66099706 |
73 | ERBB2 | 0.65741645 |
74 | PRKCZ | 0.63167337 |
75 | CDK19 | 0.63000231 |
76 | IRAK3 | 0.62576570 |
77 | ARAF | 0.62000284 |
78 | OXSR1 | 0.61552294 |
79 | CAMK4 | 0.61495561 |
80 | CAMK1 | 0.60925140 |
81 | BMPR2 | 0.60884668 |
82 | CAMK2B | 0.60687079 |
83 | CAMKK2 | 0.58368175 |
84 | RPS6KA3 | 0.58260252 |
85 | ALK | 0.55504068 |
86 | CAMK1D | 0.54777668 |
87 | MAP3K13 | 0.54629091 |
88 | DDR2 | 0.53861963 |
89 | FGFR2 | 0.53487041 |
90 | CDK3 | 0.53037991 |
91 | PTK2B | 0.51709067 |
92 | PKN1 | 0.51606053 |
93 | RET | 0.51540240 |
94 | PRKCA | 0.51162382 |
95 | PDPK1 | 0.50838289 |
96 | MAPK10 | 0.49082160 |
97 | DMPK | 0.48959130 |
98 | FYN | 0.48155906 |
99 | STK11 | 0.46173176 |
100 | PDK1 | 0.44472392 |
101 | SRC | 0.44207666 |
102 | MAPKAPK5 | 0.44005844 |
103 | PRKG1 | 0.43382007 |
104 | CAMK2D | 0.43215382 |
105 | MAP3K11 | 0.40629966 |
106 | MAPK4 | 0.40208120 |
107 | PIK3CA | 0.39747202 |
108 | PRKG2 | 0.39419558 |
109 | IGF1R | 0.39032374 |
110 | PRKACG | 0.38839511 |
111 | PRKCQ | 0.38382704 |
112 | PRKACA | 0.38199013 |
113 | MOS | 0.38070227 |
114 | PRKCB | 0.37405735 |
115 | MAP2K6 | 0.37114668 |
116 | MKNK2 | 0.36592507 |
117 | MAP3K1 | 0.35848060 |
118 | DAPK3 | 0.35493605 |
119 | CSNK1D | 0.35425133 |
120 | CCNB1 | 0.34272032 |
121 | CSNK1A1 | 0.33051890 |
122 | RAF1 | 0.32626067 |
123 | ABL2 | 0.30614696 |
124 | CSNK1E | 0.30373067 |
125 | PRKD1 | 0.30275134 |
126 | CSNK1G2 | 0.29760135 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nitrogen metabolism_Homo sapiens_hsa00910 | 5.49287847 |
2 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 3.82027085 |
3 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 3.12206142 |
4 | Nicotine addiction_Homo sapiens_hsa05033 | 3.05171232 |
5 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 2.88002275 |
6 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 2.86874243 |
7 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 2.81716199 |
8 | GABAergic synapse_Homo sapiens_hsa04727 | 2.57720380 |
9 | Caffeine metabolism_Homo sapiens_hsa00232 | 2.56943462 |
10 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 2.39948342 |
11 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 2.35389202 |
12 | Glutamatergic synapse_Homo sapiens_hsa04724 | 2.30502323 |
13 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 2.25792443 |
14 | Histidine metabolism_Homo sapiens_hsa00340 | 2.25687276 |
15 | Salivary secretion_Homo sapiens_hsa04970 | 2.10699941 |
16 | Retinol metabolism_Homo sapiens_hsa00830 | 2.09300000 |
17 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.99142213 |
18 | Circadian entrainment_Homo sapiens_hsa04713 | 1.95178280 |
19 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.95127253 |
20 | Insulin secretion_Homo sapiens_hsa04911 | 1.94183059 |
21 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.93999149 |
22 | Olfactory transduction_Homo sapiens_hsa04740 | 1.91874598 |
23 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.91779301 |
24 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.91308402 |
25 | Morphine addiction_Homo sapiens_hsa05032 | 1.87952749 |
26 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.81446436 |
27 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.78439529 |
28 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.74638349 |
29 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.64050512 |
30 | Long-term potentiation_Homo sapiens_hsa04720 | 1.63353581 |
31 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.54261173 |
32 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.53442705 |
33 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.49560494 |
34 | Amphetamine addiction_Homo sapiens_hsa05031 | 1.48312793 |
35 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.35771036 |
36 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.32035241 |
37 | Taste transduction_Homo sapiens_hsa04742 | 1.27718881 |
38 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.26256064 |
39 | Renin secretion_Homo sapiens_hsa04924 | 1.25807880 |
40 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.25570353 |
41 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.25224745 |
42 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.24972705 |
43 | Bile secretion_Homo sapiens_hsa04976 | 1.24571378 |
44 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.24192122 |
45 | Cocaine addiction_Homo sapiens_hsa05030 | 1.24140976 |
46 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 1.22183749 |
47 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.20577023 |
48 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.16386429 |
49 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.16266185 |
50 | cAMP signaling pathway_Homo sapiens_hsa04024 | 1.15521624 |
51 | Long-term depression_Homo sapiens_hsa04730 | 1.15464658 |
52 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.15417578 |
53 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.14909800 |
54 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.11801320 |
55 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.10190643 |
56 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.08948496 |
57 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.06971717 |
58 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.04777505 |
59 | Melanogenesis_Homo sapiens_hsa04916 | 1.04186853 |
60 | Gap junction_Homo sapiens_hsa04540 | 1.03443627 |
61 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.02168991 |
62 | Mineral absorption_Homo sapiens_hsa04978 | 1.01913296 |
63 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 1.00138585 |
64 | Circadian rhythm_Homo sapiens_hsa04710 | 0.98146912 |
65 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.98124572 |
66 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.96933977 |
67 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.96021561 |
68 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.95339806 |
69 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.95314521 |
70 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.93176698 |
71 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.92612271 |
72 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.90410432 |
73 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.88906567 |
74 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.88299342 |
75 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.88219659 |
76 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.86544064 |
77 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.84570966 |
78 | Peroxisome_Homo sapiens_hsa04146 | 0.81697984 |
79 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.79825893 |
80 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.79628258 |
81 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.78929020 |
82 | ABC transporters_Homo sapiens_hsa02010 | 0.76904937 |
83 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.76091290 |
84 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.74886461 |
85 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.74562815 |
86 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.73425893 |
87 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.72414590 |
88 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.72345167 |
89 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.72200690 |
90 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.72076162 |
91 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.69614533 |
92 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.68920288 |
93 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.68275104 |
94 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.67817982 |
95 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.65625718 |
96 | Axon guidance_Homo sapiens_hsa04360 | 0.65504305 |
97 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.64575462 |
98 | Carbon metabolism_Homo sapiens_hsa01200 | 0.64546979 |
99 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.64109141 |
100 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.63820731 |
101 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.62021713 |
102 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.60531896 |
103 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.60328736 |
104 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.58287194 |
105 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.57409466 |
106 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.57116594 |
107 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.56280941 |
108 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.55104321 |
109 | Glioma_Homo sapiens_hsa05214 | 0.55044879 |
110 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.54907450 |
111 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.53937802 |
112 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.53493062 |
113 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.53340365 |
114 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.49513737 |
115 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.48780559 |
116 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.47821455 |
117 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.47691882 |
118 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.45818769 |
119 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.45806758 |
120 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.44780962 |
121 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.44759982 |
122 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.42595290 |
123 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.42352791 |
124 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.39924048 |
125 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.39369948 |
126 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.38870520 |
127 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.38478918 |
128 | Prion diseases_Homo sapiens_hsa05020 | 0.38366011 |
129 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.36818022 |
130 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.36349797 |
131 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.35253382 |
132 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.34424675 |
133 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.34322001 |
134 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.33025546 |
135 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.30193013 |
136 | Lysosome_Homo sapiens_hsa04142 | 0.29761726 |
137 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.27154519 |
138 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.26486597 |
139 | Lysine degradation_Homo sapiens_hsa00310 | 0.25834384 |