SLC25A24

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a carrier protein that transports ATP-Mg exchanging it for phosphate. Multiple transcript variants encoding different isoforms have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1cell adhesion mediated by integrin (GO:0033627)4.14363787
2nuclear pore complex assembly (GO:0051292)4.01278628
3hepatocyte apoptotic process (GO:0097284)4.00896978
4protein localization to endosome (GO:0036010)3.81230997
5nuclear pore organization (GO:0006999)3.79014813
6chondrocyte proliferation (GO:0035988)3.78134751
7bundle of His cell to Purkinje myocyte communication (GO:0086069)3.68950267
8retina vasculature morphogenesis in camera-type eye (GO:0061299)3.65695083
9hemidesmosome assembly (GO:0031581)3.61188545
10COPII vesicle coating (GO:0048208)3.40821270
11regulation of transforming growth factor beta2 production (GO:0032909)3.35387364
12antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.32617362
13endodermal cell differentiation (GO:0035987)3.31174246
14mesodermal cell differentiation (GO:0048333)3.29498798
15skin morphogenesis (GO:0043589)3.24836038
16paraxial mesoderm development (GO:0048339)3.19793053
17membrane protein ectodomain proteolysis (GO:0006509)3.18316781
18positive regulation of Cdc42 GTPase activity (GO:0043089)3.17994748
19Arp2/3 complex-mediated actin nucleation (GO:0034314)3.17305798
20embryonic process involved in female pregnancy (GO:0060136)3.11638379
21neutrophil activation involved in immune response (GO:0002283)3.09044976
22positive regulation of endothelial cell apoptotic process (GO:2000353)3.08924631
23maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.05591366
24protein retention in ER lumen (GO:0006621)3.04179783
25gap junction assembly (GO:0016264)3.02484302
26wound healing, spreading of epidermal cells (GO:0035313)3.00073570
27regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.98551453
28collagen fibril organization (GO:0030199)2.97454244
29glycosphingolipid catabolic process (GO:0046479)2.97377773
30pore complex assembly (GO:0046931)2.96164078
31negative regulation of epidermal growth factor-activated receptor activity (GO:0007175)2.92628561
32substrate-dependent cell migration (GO:0006929)2.92144827
33cellular response to interferon-alpha (GO:0035457)2.90049289
34cellular protein complex localization (GO:0034629)2.88469705
35regulation of centriole replication (GO:0046599)2.86571627
36positive regulation of interferon-alpha production (GO:0032727)2.81891733
37regulation of transforming growth factor beta1 production (GO:0032908)2.80399048
38regulation of mononuclear cell migration (GO:0071675)2.76910407
39glycolipid catabolic process (GO:0019377)2.75294465
40vesicle coating (GO:0006901)2.75184636
41histone-serine phosphorylation (GO:0035404)2.75142371
42DNA unwinding involved in DNA replication (GO:0006268)2.74485020
43regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.70750748
44epithelial cell-cell adhesion (GO:0090136)2.69949320
45cellular response to vitamin D (GO:0071305)2.68102798
46negative regulation of keratinocyte proliferation (GO:0010839)2.65997866
47regulation of interferon-alpha production (GO:0032647)2.64678090
48negative regulation of DNA repair (GO:0045738)2.64535799
49mitotic chromosome condensation (GO:0007076)2.63254644
50branching involved in mammary gland duct morphogenesis (GO:0060444)2.62902428
51negative regulation of anoikis (GO:2000811)2.62567260
52regulation of interferon-beta biosynthetic process (GO:0045357)2.62264567
53midgut development (GO:0007494)2.60862305
54mammary gland epithelial cell proliferation (GO:0033598)2.60174204
55regulation of interleukin-8 secretion (GO:2000482)2.59203092
56regulation of tight junction assembly (GO:2000810)2.58593981
57oligosaccharide catabolic process (GO:0009313)2.58040311
58protein complex localization (GO:0031503)2.57497699
59membrane raft organization (GO:0031579)2.57057715
60intestinal epithelial cell development (GO:0060576)2.55532151
61mRNA transcription (GO:0009299)2.55490935
62chondrocyte development (GO:0002063)2.55206262
63positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.54008731
64actin nucleation (GO:0045010)2.52536101
65apoptotic cell clearance (GO:0043277)2.52390472
66regulation of sister chromatid cohesion (GO:0007063)2.52279600
67tight junction assembly (GO:0070830)2.51903084
68regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.51507810
69cell migration involved in sprouting angiogenesis (GO:0002042)2.49946225
70positive regulation of actin filament depolymerization (GO:0030836)2.49885961
71negative regulation of protein localization to plasma membrane (GO:1903077)2.49072803
72negative regulation of chondrocyte differentiation (GO:0032331)2.48717815
73wound healing, spreading of cells (GO:0044319)2.48690135
74response to interferon-alpha (GO:0035455)2.47631776
75mitotic metaphase plate congression (GO:0007080)2.46624320
76actin filament depolymerization (GO:0030042)2.45981498
77negative regulation of fatty acid transport (GO:2000192)2.44410813
78germ cell migration (GO:0008354)2.44285103
79cellular response to vitamin (GO:0071295)2.44087978
80regulation of syncytium formation by plasma membrane fusion (GO:0060142)2.43962303
81positive regulation of keratinocyte differentiation (GO:0045618)2.43557461
82protein localization to cell surface (GO:0034394)2.42332054
83glomerular visceral epithelial cell development (GO:0072015)2.42209895
84nucleotide-sugar biosynthetic process (GO:0009226)2.41907224
85hypotonic response (GO:0006971)2.40817534
86antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.39687442
87antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.39687442
88nucleobase-containing small molecule interconversion (GO:0015949)2.38853334
89mitotic cytokinesis (GO:0000281)2.38718377
90cell-substrate junction assembly (GO:0007044)2.37394946
91ribosome assembly (GO:0042255)2.36565414
92desmosome organization (GO:0002934)2.36369006
93retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.36268459
94vascular endothelial growth factor signaling pathway (GO:0038084)2.35612639
95mesenchymal-epithelial cell signaling (GO:0060638)2.35431016
96positive regulation of glycoprotein metabolic process (GO:1903020)2.35076251
97hippo signaling (GO:0035329)2.34464522
98metaphase plate congression (GO:0051310)2.34336627
99establishment of endothelial barrier (GO:0061028)2.34246045
100mitotic sister chromatid cohesion (GO:0007064)2.33786454
101regulation of protein heterodimerization activity (GO:0043497)2.32935830
102positive regulation of macrophage differentiation (GO:0045651)2.32490369
103axon extension involved in axon guidance (GO:0048846)2.32478933
104neuron projection extension involved in neuron projection guidance (GO:1902284)2.32478933
105regulation of transforming growth factor beta production (GO:0071634)2.32131227
106pinocytosis (GO:0006907)2.31445310
107positive regulation of epithelial to mesenchymal transition (GO:0010718)2.30902702
108positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.29870761
109regulation of early endosome to late endosome transport (GO:2000641)2.29682748
110positive regulation of osteoblast proliferation (GO:0033690)2.29496817
111cytoskeleton-dependent cytokinesis (GO:0061640)2.29121322
112regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.28380396
113leukocyte aggregation (GO:0070486)2.28060742
114regulation of cardioblast differentiation (GO:0051890)2.27470744
115regulation of chemokine secretion (GO:0090196)2.27365876
116regulation of branching involved in salivary gland morphogenesis (GO:0060693)2.27037030
117endothelial tube morphogenesis (GO:0061154)2.26641497
118morphogenesis of an endothelium (GO:0003159)2.26641497
119establishment of chromosome localization (GO:0051303)2.25867105
120integrin-mediated signaling pathway (GO:0007229)2.24774411
121regulation of anoikis (GO:2000209)2.24241823
122membrane protein proteolysis (GO:0033619)2.24052962
123regulation of keratinocyte differentiation (GO:0045616)2.23950492
124regulation of integrin activation (GO:0033623)2.23166037
125membrane budding (GO:0006900)2.23093768
126UDP-N-acetylglucosamine metabolic process (GO:0006047)2.20597114
127localization within membrane (GO:0051668)2.20437838
128iron ion import (GO:0097286)2.20153795
129activation of Rac GTPase activity (GO:0032863)2.19944232
130substrate adhesion-dependent cell spreading (GO:0034446)2.19765503
131ER overload response (GO:0006983)2.19659982
132protein localization to chromosome, centromeric region (GO:0071459)2.19605977
133endothelial cell morphogenesis (GO:0001886)2.18837644
134sequestering of metal ion (GO:0051238)2.18471851
135surfactant homeostasis (GO:0043129)2.18319398
136regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307)2.17488031
137regulation of protein localization to plasma membrane (GO:1903076)2.17117134
138protein heterotrimerization (GO:0070208)2.16799038
139maternal placenta development (GO:0001893)2.16561349
140muscle cell migration (GO:0014812)2.16360366
141leukocyte cell-cell adhesion (GO:0007159)2.16102011
142ceramide catabolic process (GO:0046514)2.15730772
143T cell apoptotic process (GO:0070231)2.15229601
144platelet aggregation (GO:0070527)2.14244222
145response to laminar fluid shear stress (GO:0034616)2.13736795
146positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.13595536
147cell differentiation involved in embryonic placenta development (GO:0060706)2.12906627
148collagen metabolic process (GO:0032963)2.12310214
149extracellular matrix disassembly (GO:0022617)2.11401679
150COPI coating of Golgi vesicle (GO:0048205)2.11399581
151Golgi transport vesicle coating (GO:0048200)2.11399581
152positive regulation of natural killer cell differentiation (GO:0032825)2.11156040
153regulation of nephron tubule epithelial cell differentiation (GO:0072182)2.10892373
154cytokinetic process (GO:0032506)2.10089792
155production of molecular mediator involved in inflammatory response (GO:0002532)2.09615750
156antigen processing and presentation of endogenous antigen (GO:0019883)2.09601732
157basement membrane organization (GO:0071711)2.09133916
158neutrophil activation (GO:0042119)2.09124842
159barbed-end actin filament capping (GO:0051016)2.09115514
160dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.09041125
161positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.08920901
162heterochromatin organization (GO:0070828)2.07888677
163regulation of podosome assembly (GO:0071801)2.07012836
164positive regulation of interleukin-8 secretion (GO:2000484)2.06932997
165regulation of integrin-mediated signaling pathway (GO:2001044)2.06791062
166cellular extravasation (GO:0045123)2.06684642
167multicellular organismal macromolecule metabolic process (GO:0044259)2.05574517
168positive regulation of lamellipodium assembly (GO:0010592)2.04786423
169response to muramyl dipeptide (GO:0032495)2.04502466
170leukocyte tethering or rolling (GO:0050901)2.03599021
171modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.03370036
172modulation by symbiont of host immune response (GO:0052553)2.03370036

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human6.21468375
2TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse3.74137595
3FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.73024971
4TRIM28_21343339_ChIP-Seq_HEK293_Human3.65685194
5EGR1_19374776_ChIP-ChIP_THP-1_Human3.56289170
6NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.49795600
7SMAD4_19686287_ChIP-ChIP_HaCaT_Human3.00199633
8* RARG_19884340_ChIP-ChIP_MEFs_Mouse2.90103318
9IRF8_22096565_ChIP-ChIP_GC-B_Human2.89354742
10E2F7_22180533_ChIP-Seq_HELA_Human2.60801780
11IRF8_21731497_ChIP-ChIP_J774_Mouse2.37865461
12RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human2.31667859
13* SMAD3_18955504_ChIP-ChIP_HaCaT_Human2.28351938
14* SMAD2_18955504_ChIP-ChIP_HaCaT_Human2.28351938
15STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.24105876
16FOXM1_23109430_ChIP-Seq_U2OS_Human2.22316505
17* MYB_21317192_ChIP-Seq_ERMYB_Mouse2.18324398
18PRDM5_23873026_ChIP-Seq_MEFs_Mouse2.16225311
19CLOCK_20551151_ChIP-Seq_293T_Human2.15610065
20* ZNF217_24962896_ChIP-Seq_MCF-7_Human2.10395645
21STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.08720858
22NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.08310415
23ESR2_21235772_ChIP-Seq_MCF-7_Human2.01618966
24SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.01112255
25CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.99530471
26ZNF263_19887448_ChIP-Seq_K562_Human1.95900657
27RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.95261720
28IRF8_27001747_Chip-Seq_BMDM_Mouse1.93600874
29HIF1A_21447827_ChIP-Seq_MCF-7_Human1.89454757
30SOX2_20726797_ChIP-Seq_SW620_Human1.86670555
31Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.85151701
32IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.84405325
33CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.83916140
34TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.83681447
35AR_21909140_ChIP-Seq_LNCAP_Human1.83238879
36TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.78657773
37* MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.76254652
38KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.74681024
39CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.74437870
40NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.74310941
41CJUN_26792858_Chip-Seq_BT549_Human1.72653647
42KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.71932099
43BRD4_27068464_Chip-Seq_AML-cells_Mouse1.69113876
44SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.69058830
45ELK3_25401928_ChIP-Seq_HUVEC_Human1.65749131
46BRD4_25478319_ChIP-Seq_HGPS_Human1.65691861
47CDX2_20551321_ChIP-Seq_CACO-2_Human1.64540383
48GATA2_21666600_ChIP-Seq_HMVEC_Human1.61266757
49ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.59805356
50PPAR_26484153_Chip-Seq_NCI-H1993_Human1.59300581
51SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.58482526
52BP1_19119308_ChIP-ChIP_Hs578T_Human1.54605801
53WT1_19549856_ChIP-ChIP_CCG9911_Human1.53231833
54ZFX_18555785_ChIP-Seq_MESCs_Mouse1.52163558
55FOXO3_23340844_ChIP-Seq_DLD1_Human1.51229764
56FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.48160070
57JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.47631735
58MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.47289686
59TFEB_21752829_ChIP-Seq_HELA_Human1.46380788
60ESR1_21235772_ChIP-Seq_MCF-7_Human1.46106040
61FOXM1_26456572_ChIP-Seq_MCF-7_Human1.44017335
62MYB_26560356_Chip-Seq_TH2_Human1.41907852
63KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.41457436
64STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.40061796
65* ATF3_27146783_Chip-Seq_COLON_Human1.39707457
66ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.38542095
67* GATA3_24758297_ChIP-Seq_MCF-7_Human1.35667357
68IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.35063887
69GATA4_25053715_ChIP-Seq_YYC3_Human1.35007304
70MAF_26560356_Chip-Seq_TH1_Human1.34383910
71KLF4_18555785_ChIP-Seq_MESCs_Mouse1.34267876
72TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.34134344
73STAT4_19710469_ChIP-ChIP_TH1__Mouse1.33606328
74SALL4_18804426_ChIP-ChIP_XEN_Mouse1.32750968
75SPI1_23547873_ChIP-Seq_NB4_Human1.31783823
76SMAD_19615063_ChIP-ChIP_OVARY_Human1.31761458
77NELFA_20434984_ChIP-Seq_ESCs_Mouse1.31520669
78SALL1_21062744_ChIP-ChIP_HESCs_Human1.29972852
79* GATA6_25053715_ChIP-Seq_YYC3_Human1.29715546
80VDR_24763502_ChIP-Seq_THP-1_Human1.28596631
81ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.28264674
82* SOX2_27498859_Chip-Seq_STOMACH_Mouse1.27097671
83NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.26341425
84TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.26161825
85JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.24361071
86STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.23434645
87FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.23381084
88UBF1/2_26484160_Chip-Seq_HMECs_Human1.22173267
89RUNX1_22412390_ChIP-Seq_EML_Mouse1.21610561
90CDX2_19796622_ChIP-Seq_MESCs_Mouse1.21214119
91CHD1_26751641_Chip-Seq_LNCaP_Human1.20433220
92AHR_22903824_ChIP-Seq_MCF-7_Human1.18907547
93SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.17791321
94PU_27001747_Chip-Seq_BMDM_Mouse1.17493547
95ELK1_22589737_ChIP-Seq_MCF10A_Human1.16619097
96SOX17_20123909_ChIP-Seq_XEN_Mouse1.14960730
97GATA1_22025678_ChIP-Seq_K562_Human1.14160782
98WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.13935493
99* FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.11617219
100ELF5_23300383_ChIP-Seq_T47D_Human1.11434766
101TCF7_22412390_ChIP-Seq_EML_Mouse1.10932924
102MYB_26560356_Chip-Seq_TH1_Human1.10321236
103P300_27058665_Chip-Seq_ZR-75-30cells_Human1.10094636
104MYCN_18555785_ChIP-Seq_MESCs_Mouse1.10089995
105E2F4_17652178_ChIP-ChIP_JURKAT_Human1.09194287
106ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.08658109
107NRF2_20460467_ChIP-Seq_MEFs_Mouse1.08492228
108NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.08492228
109* ELK1_19687146_ChIP-ChIP_HELA_Human1.08321886
110VDR_24787735_ChIP-Seq_THP-1_Human1.08279318
111TCF3_18692474_ChIP-Seq_MEFs_Mouse1.07827936
112* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.07566473
113VDR_21846776_ChIP-Seq_THP-1_Human1.06358875
114ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.06221161
115MYC_22102868_ChIP-Seq_BL_Human1.05973375
116POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.05762522
117STAT6_21828071_ChIP-Seq_BEAS2B_Human1.04604699
118UTX_26944678_Chip-Seq_JUKART_Human1.04078022
119PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.03913450
120E2F1_21310950_ChIP-Seq_MCF-7_Human1.03658162
121SCL_19346495_ChIP-Seq_HPC-7_Human1.01772314
122ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.01630933
123EP300_21415370_ChIP-Seq_HL-1_Mouse1.01582275
124P63_26484246_Chip-Seq_KERATINOCYTES_Human1.01513173
125RUNX1_27514584_Chip-Seq_MCF-7_Human1.00985513
126RACK7_27058665_Chip-Seq_MCF-7_Human1.00798049
127CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.99417417
128RUNX_20019798_ChIP-Seq_JUKART_Human0.98517862
129SPI1_23127762_ChIP-Seq_K562_Human0.98067559
130EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.97930592
131TP53_16413492_ChIP-PET_HCT116_Human0.97393175
132KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.96845006
133MYC_18555785_ChIP-Seq_MESCs_Mouse0.96388175
134HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.94420837
135ESR1_20079471_ChIP-ChIP_T-47D_Human0.94416228
136SOX9_24532713_ChIP-Seq_HFSC_Mouse0.94318181
137SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.94052692
138ESR1_15608294_ChIP-ChIP_MCF-7_Human0.92530911
139NKX2-5_21415370_ChIP-Seq_HL-1_Mouse0.91812103
140* KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.90782984

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen3.98033806
2MP0003705_abnormal_hypodermis_morpholog3.57527569
3MP0006054_spinal_hemorrhage3.18249220
4MP0010352_gastrointestinal_tract_polyps2.86875503
5MP0005275_abnormal_skin_tensile2.72687382
6MP0010234_abnormal_vibrissa_follicle2.64387632
7MP0003191_abnormal_cellular_cholesterol2.28557726
8MP0003566_abnormal_cell_adhesion2.21216602
9MP0002009_preneoplasia2.05978695
10MP0003300_gastrointestinal_ulcer2.01774137
11MP0005023_abnormal_wound_healing1.96100463
12MP0005503_abnormal_tendon_morphology1.95952908
13MP0003279_aneurysm1.90007745
14MP0004272_abnormal_basement_membrane1.89841492
15MP0005076_abnormal_cell_differentiation1.77311671
16MP0002060_abnormal_skin_morphology1.77166776
17MP0009384_cardiac_valve_regurgitation1.75847437
18MP0005623_abnormal_meninges_morphology1.72024017
19MP0000537_abnormal_urethra_morphology1.70588656
20MP0009840_abnormal_foam_cell1.68613422
21MP0002796_impaired_skin_barrier1.68083924
22MP0003091_abnormal_cell_migration1.63036457
23MP0001958_emphysema1.62820824
24MP0003436_decreased_susceptibility_to1.59550368
25MP0004947_skin_inflammation1.57041142
26MP0005058_abnormal_lysosome_morphology1.56878503
27MP0000733_abnormal_muscle_development1.52477329
28MP0009053_abnormal_anal_canal1.52329005
29MP0004957_abnormal_blastocyst_morpholog1.50913133
30MP0000858_altered_metastatic_potential1.48202259
31MP0005451_abnormal_body_composition1.47444296
32MP0010030_abnormal_orbit_morphology1.43081449
33MP0002166_altered_tumor_susceptibility1.41472740
34MP0002877_abnormal_melanocyte_morpholog1.41245857
35MP0010155_abnormal_intestine_physiology1.39314207
36MP0009785_altered_susceptibility_to1.39238899
37MP0004233_abnormal_muscle_weight1.36723767
38MP0010368_abnormal_lymphatic_system1.35207206
39MP0003453_abnormal_keratinocyte_physiol1.34373900
40MP0000490_abnormal_crypts_of1.30050373
41MP0010307_abnormal_tumor_latency1.29829401
42MP0000462_abnormal_digestive_system1.28766585
43MP0001835_abnormal_antigen_presentation1.28629056
44MP0001533_abnormal_skeleton_physiology1.27542940
45MP0003448_altered_tumor_morphology1.27422423
46MP0001879_abnormal_lymphatic_vessel1.26167379
47MP0002006_tumorigenesis1.24821690
48MP0004782_abnormal_surfactant_physiolog1.22188097
49MP0004808_abnormal_hematopoietic_stem1.15734530
50MP0001873_stomach_inflammation1.14470109
51MP0005257_abnormal_intraocular_pressure1.14427879
52MP0001243_abnormal_dermal_layer1.13592881
53MP0004264_abnormal_extraembryonic_tissu1.13042033
54MP0009278_abnormal_bone_marrow1.12548943
55MP0000767_abnormal_smooth_muscle1.11097243
56MP0000685_abnormal_immune_system1.10978586
57MP0003941_abnormal_skin_development1.09023261
58MP0005390_skeleton_phenotype1.06392731
59MP0002086_abnormal_extraembryonic_tissu1.05557914
60MP0002419_abnormal_innate_immunity1.05397604
61MP0002933_joint_inflammation1.05317083
62MP0003303_peritoneal_inflammation1.05043144
63MP0002098_abnormal_vibrissa_morphology1.04999307
64MP0002998_abnormal_bone_remodeling1.04764189
65MP0003221_abnormal_cardiomyocyte_apopto1.04524426
66MP0008932_abnormal_embryonic_tissue1.04129972
67MP0005367_renal/urinary_system_phenotyp1.03950386
68MP0000516_abnormal_urinary_system1.03950386
69MP0010678_abnormal_skin_adnexa1.03638369
70MP0002148_abnormal_hypersensitivity_rea1.03594500
71MP0003693_abnormal_embryo_hatching1.02940456
72MP0002896_abnormal_bone_mineralization1.02561084
73MP0005197_abnormal_uvea_morphology1.02356603
74MP0002452_abnormal_antigen_presenting1.01964932
75MP0008057_abnormal_DNA_replication1.01697458
76MP0005508_abnormal_skeleton_morphology1.00934255
77MP0005165_increased_susceptibility_to0.99092471
78MP0003828_pulmonary_edema0.99065001
79MP0005025_abnormal_response_to0.98560076
80MP0000627_abnormal_mammary_gland0.98422728
81MP0000569_abnormal_digit_pigmentation0.98344733
82MP0004185_abnormal_adipocyte_glucose0.98109196
83MP0002396_abnormal_hematopoietic_system0.96961265
84MP0009697_abnormal_copulation0.96823976
85MP0001730_embryonic_growth_arrest0.96345135
86MP0001216_abnormal_epidermal_layer0.96215019
87MP0000762_abnormal_tongue_morphology0.95935620
88MP0002697_abnormal_eye_size0.95848029
89MP0005360_urolithiasis0.95153427
90MP0005000_abnormal_immune_tolerance0.95090608
91MP0002405_respiratory_system_inflammati0.94919026
92MP0000465_gastrointestinal_hemorrhage0.94616982
93MP0003984_embryonic_growth_retardation0.92311783
94MP0005397_hematopoietic_system_phenotyp0.91725793
95MP0001545_abnormal_hematopoietic_system0.91725793
96MP0002113_abnormal_skeleton_development0.90917685
97MP0003385_abnormal_body_wall0.90607094
98MP0000383_abnormal_hair_follicle0.90314722
99MP0000477_abnormal_intestine_morphology0.89859913
100MP0005380_embryogenesis_phenotype0.89477510
101MP0001672_abnormal_embryogenesis/_devel0.89477510
102MP0002088_abnormal_embryonic_growth/wei0.89388372
103MP0003795_abnormal_bone_structure0.88992159
104MP0003724_increased_susceptibility_to0.88766752
105MP0008007_abnormal_cellular_replicative0.88661723
106MP0009250_abnormal_appendicular_skeleto0.88060642
107MP0002084_abnormal_developmental_patter0.87768861
108MP0002092_abnormal_eye_morphology0.86601564
109MP0005248_abnormal_Harderian_gland0.86046217
110MP0001849_ear_inflammation0.86024646
111MP0001819_abnormal_immune_cell0.85689748
112MP0009333_abnormal_splenocyte_physiolog0.85508529
113MP0000343_altered_response_to0.85037399
114MP0002282_abnormal_trachea_morphology0.83919137
115MP0002420_abnormal_adaptive_immunity0.83367163
116MP0000467_abnormal_esophagus_morphology0.81595393
117MP0001697_abnormal_embryo_size0.81577819
118MP0009780_abnormal_chondrocyte_physiolo0.81099907
119MP0003183_abnormal_peptide_metabolism0.80272892
120MP0001915_intracranial_hemorrhage0.80005629
121MP0001542_abnormal_bone_strength0.79971181
122MP0001790_abnormal_immune_system0.79792586
123MP0005387_immune_system_phenotype0.79792586
124MP0002085_abnormal_embryonic_tissue0.78940827
125MP0003950_abnormal_plasma_membrane0.78860934
126MP0001845_abnormal_inflammatory_respons0.78254073
127MP0002254_reproductive_system_inflammat0.77608826
128MP0000350_abnormal_cell_proliferation0.77357085
129MP0003045_fibrosis0.77333539
130MP0005464_abnormal_platelet_physiology0.76924744
131MP0005621_abnormal_cell_physiology0.76627970
132MP0006082_CNS_inflammation0.76506866
133MP0003077_abnormal_cell_cycle0.75521520
134MP0002115_abnormal_skeleton_extremities0.74797524
135MP0001727_abnormal_embryo_implantation0.74471237
136MP0001881_abnormal_mammary_gland0.74193310
137MP0001299_abnormal_eye_distance/0.74057912
138MP0000377_abnormal_hair_follicle0.73752231
139MP0005501_abnormal_skin_physiology0.73308821
140MP0003937_abnormal_limbs/digits/tail_de0.73279425
141MP0000432_abnormal_head_morphology0.73145734
142MP0001800_abnormal_humoral_immune0.72949088
143MP0002723_abnormal_immune_serum0.72743929
144MP0001191_abnormal_skin_condition0.72742905
145MP0005193_abnormal_anterior_eye0.72281022
146MP0000428_abnormal_craniofacial_morphol0.72250507
147MP0000163_abnormal_cartilage_morphology0.71594598
148MP0001614_abnormal_blood_vessel0.69695902

Predicted human phenotypes

RankGene SetZ-score
1Premature rupture of membranes (HP:0001788)4.48970034
2Protrusio acetabuli (HP:0003179)4.48631129
3Atrophic scars (HP:0001075)3.84388450
4Cervical subluxation (HP:0003308)3.60693199
5Spinal cord lesions (HP:0100561)3.58204494
6Syringomyelia (HP:0003396)3.58204494
7Aortic dissection (HP:0002647)3.52244285
8Aortic aneurysm (HP:0004942)3.22948025
9Osteolytic defects of the hand bones (HP:0009699)3.04379057
10Osteolytic defects of the phalanges of the hand (HP:0009771)3.04379057
11Peritonitis (HP:0002586)3.03695906
12Ankle contracture (HP:0006466)2.99485197
13Fragile skin (HP:0001030)2.94831063
14Increased density of long bones (HP:0006392)2.87576170
15Dilatation of the ascending aorta (HP:0005111)2.78430382
16Subacute progressive viral hepatitis (HP:0006572)2.66662620
17Cerebral aneurysm (HP:0004944)2.65633986
18Shallow orbits (HP:0000586)2.63291034
19Vertebral compression fractures (HP:0002953)2.62897808
20Right ventricular cardiomyopathy (HP:0011663)2.59654217
21Wormian bones (HP:0002645)2.56489963
22Abnormality of the umbilical cord (HP:0010881)2.55080732
23Soft skin (HP:0000977)2.52364395
24Insidious onset (HP:0003587)2.50801766
25Termporal pattern (HP:0011008)2.50801766
26Absent frontal sinuses (HP:0002688)2.45885633
27Abnormality of the fetal cardiovascular system (HP:0010948)2.39505730
28Abnormal umbilical cord blood vessels (HP:0011403)2.39505730
29Single umbilical artery (HP:0001195)2.39505730
30Micronodular cirrhosis (HP:0001413)2.39245906
31Tetraparesis (HP:0002273)2.38428531
32Deep philtrum (HP:0002002)2.36700205
33Radial bowing (HP:0002986)2.35467346
34Milia (HP:0001056)2.32363392
35Increased connective tissue (HP:0009025)2.32288979
36Abnormality of liposaccharide metabolism (HP:0010968)2.32181951
37Abnormality of glycosphingolipid metabolism (HP:0004343)2.32181951
38Abnormality of glycolipid metabolism (HP:0010969)2.32181951
39Short nail (HP:0001799)2.31502981
40Curly hair (HP:0002212)2.31345993
41Ankyloglossia (HP:0010296)2.31024926
42Eczematoid dermatitis (HP:0000976)2.28694161
43Spondylolisthesis (HP:0003302)2.27424611
44Microglossia (HP:0000171)2.26359511
45Vascular tortuosity (HP:0004948)2.25453544
46J-shaped sella turcica (HP:0002680)2.24215932
47Increased mean platelet volume (HP:0011877)2.22791354
48Neonatal short-limb short stature (HP:0008921)2.20447823
49Abnormality of the calcaneus (HP:0008364)2.18670176
50Mildly elevated creatine phosphokinase (HP:0008180)2.17918085
51Mesomelia (HP:0003027)2.17462159
52Myositis (HP:0100614)2.16080282
53Mitral valve prolapse (HP:0001634)2.15326692
54Abnormal platelet volume (HP:0011876)2.13759080
55Abnormality of oral frenula (HP:0000190)2.12615978
56Abnormal foot bone ossification (HP:0010675)2.12258547
57Rectal prolapse (HP:0002035)2.10232597
58Recurrent abscess formation (HP:0002722)2.09795048
59Arterial tortuosity (HP:0005116)2.09300047
60Cupped ribs (HP:0000887)2.08483394
61Bladder diverticulum (HP:0000015)2.05776516
62Spinal rigidity (HP:0003306)2.04856515
63Blue sclerae (HP:0000592)2.04225770
64Thin bony cortex (HP:0002753)2.03006253
65Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.01777812
66Short 4th metacarpal (HP:0010044)2.01777812
67Abnormality of the distal phalanx of the thumb (HP:0009617)2.01770983
68Abnormality of the acetabulum (HP:0003170)2.01274151
69Natal tooth (HP:0000695)2.00088067
70Spinal cord compression (HP:0002176)1.99434294
71Thick nail (HP:0001805)1.98534905
72Abnormalities of placenta or umbilical cord (HP:0001194)1.98380128
73Broad face (HP:0000283)1.98065128
74Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.97191018
75Asymmetry of the thorax (HP:0001555)1.95620533
76Wrist flexion contracture (HP:0001239)1.95533245
77Hematochezia (HP:0002573)1.95334190
78Prostate neoplasm (HP:0100787)1.93829740
79Selective tooth agenesis (HP:0001592)1.93450423
80Aplasia/Hypoplasia of the vertebrae (HP:0008515)1.93033711
81Vertebral hypoplasia (HP:0008417)1.93033711
82Abnormality of the 2nd finger (HP:0004100)1.92827709
83Abdominal distention (HP:0003270)1.92169749
84Short middle phalanx of the 5th finger (HP:0004220)1.92129469
85Abnormality of the distal phalanges of the toes (HP:0010182)1.91584538
86Shoulder girdle muscle weakness (HP:0003547)1.91547126
87Orchitis (HP:0100796)1.91202541
88Esophageal varix (HP:0002040)1.90274516
89Ulnar bowing (HP:0003031)1.88820885
90Pelvic girdle muscle weakness (HP:0003749)1.88572368
91Flat acetabular roof (HP:0003180)1.88475418
92Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.88457961
93Biconcave vertebral bodies (HP:0004586)1.88231873
94Vacuolated lymphocytes (HP:0001922)1.86709130
95Disinhibition (HP:0000734)1.85571994
96Papillary thyroid carcinoma (HP:0002895)1.85079500
97Cardiovascular calcification (HP:0011915)1.84393061
98Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.82787471
99Deviation of the thumb (HP:0009603)1.82235718
100Alopecia of scalp (HP:0002293)1.81565247
101Pustule (HP:0200039)1.81148613
102Limb-girdle muscle atrophy (HP:0003797)1.80664885
103Abnormality of dentin (HP:0010299)1.77616990
104Delayed closure of the anterior fontanelle (HP:0001476)1.75883952
105Beaking of vertebral bodies (HP:0004568)1.75853062
106Ileus (HP:0002595)1.74897426
107Type 1 muscle fiber predominance (HP:0003803)1.74801790
108Spastic diplegia (HP:0001264)1.74536814
109Cortical dysplasia (HP:0002539)1.74515193
110Tibial bowing (HP:0002982)1.74439730
111Bone pain (HP:0002653)1.73368749
112Thoracolumbar scoliosis (HP:0002944)1.72536493
113Malignant gastrointestinal tract tumors (HP:0006749)1.72437617
114Gastrointestinal carcinoma (HP:0002672)1.72437617
115Genu recurvatum (HP:0002816)1.72323918
116Abnormal vertebral ossification (HP:0100569)1.71672634
117Onycholysis (HP:0001806)1.70320607
118Proximal placement of thumb (HP:0009623)1.70115316
119Missing ribs (HP:0000921)1.70085462
120Ureteral obstruction (HP:0006000)1.69791571
121Bowed forearm bones (HP:0003956)1.69572680
122Bowing of the arm (HP:0006488)1.69572680
123Back pain (HP:0003418)1.69158493
124Platyspondyly (HP:0000926)1.69029089
125Pterygium (HP:0001059)1.68421640
126Abnormality of the peritoneum (HP:0002585)1.67993377
127Follicular hyperkeratosis (HP:0007502)1.67973258
128Elbow flexion contracture (HP:0002987)1.67776774
129Transitional cell carcinoma of the bladder (HP:0006740)1.67681128
130Abnormality of the hip-girdle musculature (HP:0001445)1.67588618
131Abnormality of the musculature of the pelvis (HP:0001469)1.67588618
132Distal lower limb muscle weakness (HP:0009053)1.66856727
133Deformed sella turcica (HP:0002681)1.66340659
134Leiomyosarcoma (HP:0100243)1.66278973
135Uterine leiomyosarcoma (HP:0002891)1.66278973
136Camptodactyly of toe (HP:0001836)1.66267800
137Persistence of primary teeth (HP:0006335)1.65943421
138Breast carcinoma (HP:0003002)1.65303552
139Broad metatarsal (HP:0001783)1.64492480
140Coxa vara (HP:0002812)1.63428330
141Vascular calcification (HP:0004934)1.63253832
142Focal segmental glomerulosclerosis (HP:0000097)1.63203984
143Long toe (HP:0010511)1.63000534
144Abnormality of the frontal sinuses (HP:0002687)1.62136900
145Mucopolysacchariduria (HP:0008155)1.61946507
146Urinary glycosaminoglycan excretion (HP:0003541)1.61946507
147Recurrent bacterial skin infections (HP:0005406)1.61103976
148Ureteral stenosis (HP:0000071)1.60544861
149Thyroid carcinoma (HP:0002890)1.60194722
150Mitral regurgitation (HP:0001653)1.59825461
151Aneurysm (HP:0002617)1.59615013
152Distal lower limb amyotrophy (HP:0008944)1.58937482
153Myocardial infarction (HP:0001658)1.58230488
154Delayed cranial suture closure (HP:0000270)1.58017371
155Deviation of the hallux (HP:0010051)1.56865443
156Gastrointestinal dysmotility (HP:0002579)1.55851359
157Bicuspid aortic valve (HP:0001647)1.55116334
158Periodontitis (HP:0000704)1.54617198

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TTN3.13589168
2FRK3.11953677
3MAP3K122.71054114
4TESK12.44224101
5TRIM282.31405413
6TRIB32.28893213
7STK102.21112074
8DDR22.20219273
9EPHA22.20154502
10LATS22.15981991
11BRSK22.10376686
12MST1R2.07942475
13RPS6KA42.06315105
14PKN22.01785129
15TRPM71.96750806
16RIPK11.92812095
17LRRK21.84509440
18PAK41.82403179
19MST41.80662941
20MAP3K141.76870628
21BCR1.74333715
22PTK61.69965170
23LATS11.66221391
24TBK11.62331618
25EIF2AK31.55154791
26NEK91.54220172
27SIK31.51989213
28EPHB21.51824148
29TESK21.49646623
30ERBB41.48797673
31SRPK11.46663607
32PIM21.45253099
33PRKG21.44557753
34PDGFRA1.44351249
35JAK31.43337533
36TGFBR11.38076713
37STK31.37095649
38LIMK11.35876970
39PTK21.34966533
40BMX1.30804087
41SCYL21.29773678
42TTK1.26061699
43BLK1.25752157
44PIK3CA1.23130828
45PAK21.22071171
46NME21.20898729
47NUAK11.19586855
48FLT31.19264331
49TGFBR21.18783540
50EEF2K1.13307734
51TYK21.12875587
52KDR1.12624360
53YES11.11637637
54KIT1.11374680
55STK241.10461712
56MOS1.09219139
57NEK11.09198366
58MAP3K81.09023290
59CDK61.08944788
60ERBB31.08011950
61DMPK1.04626437
62MAP3K21.03264696
63MET1.01385401
64PDK21.00487647
65BMPR20.97285323
66ERN10.96773912
67KSR10.96684659
68MAP3K30.93175854
69STK38L0.91620997
70MARK30.91273731
71FER0.90898655
72NEK60.90637583
73TSSK60.90456095
74SMG10.89933164
75MAP3K100.87923299
76RPS6KB20.87607397
77EIF2AK10.87606582
78MYLK0.86594919
79IKBKE0.83695203
80ICK0.81534174
81CLK10.79224836
82IKBKB0.76657770
83AURKB0.76538601
84EPHA30.75203460
85ABL20.74845359
86CHUK0.74559673
87CSK0.72816990
88ZAK0.70996255
89ILK0.70390761
90PIK3CG0.68915166
91JAK10.68806416
92MAP3K60.67187065
93ZAP700.66706737
94PIM10.66369734
95MAP2K20.65361325
96MAPKAPK20.64886573
97MAP2K10.64781995
98IRAK40.63700386
99BUB10.63156425
100TAF10.62986076
101FGFR10.60037057
102MTOR0.59519590
103MAP2K30.59439164
104PDGFRB0.58279289
105ACVR1B0.56996955
106FGFR30.56973493
107PBK0.54407261
108CSF1R0.52977504
109MAPKAPK30.51518935
110DYRK30.50994066
111LMTK20.50590898
112TXK0.48334312
113PAK10.48048548
114RPS6KA20.47775057
115MAP4K10.47713167
116EPHB10.47430322
117ROCK10.46717198
118PLK30.45825318
119CDK120.45617631
120DYRK1B0.44966200
121NEK20.44960794
122TIE10.44119910
123IRAK30.42654207
124CDK70.40920797
125SIK10.40235725
126STK40.40117653
127FGFR40.39985965
128MUSK0.39721595
129TAOK30.38861106
130EGFR0.38367516
131KSR20.38091115
132WEE10.37873648
133MKNK10.36797464
134ABL10.36602500
135CDK90.36346458
136PLK10.35586236
137IRAK20.34659111
138MATK0.34558996
139HCK0.34160076
140MELK0.34008367
141RET0.32303474
142ROCK20.32290294

Predicted pathways (KEGG)

RankGene SetZ-score
1Bacterial invasion of epithelial cells_Homo sapiens_hsa051002.19432481
2Pathogenic Escherichia coli infection_Homo sapiens_hsa051302.14465166
3ECM-receptor interaction_Homo sapiens_hsa045122.11894400
4Leishmaniasis_Homo sapiens_hsa051402.09828417
5Adherens junction_Homo sapiens_hsa045202.02105202
6Leukocyte transendothelial migration_Homo sapiens_hsa046701.95785797
7Small cell lung cancer_Homo sapiens_hsa052221.93163736
8Focal adhesion_Homo sapiens_hsa045101.90325252
9Shigellosis_Homo sapiens_hsa051311.88387580
10Proteoglycans in cancer_Homo sapiens_hsa052051.70442261
11Toxoplasmosis_Homo sapiens_hsa051451.68071362
12Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.66264759
13Antigen processing and presentation_Homo sapiens_hsa046121.64633180
14Malaria_Homo sapiens_hsa051441.60278268
15Viral myocarditis_Homo sapiens_hsa054161.54877655
16Salmonella infection_Homo sapiens_hsa051321.53342922
17Legionellosis_Homo sapiens_hsa051341.52934096
18Bladder cancer_Homo sapiens_hsa052191.52724345
19TNF signaling pathway_Homo sapiens_hsa046681.50421846
20Non-homologous end-joining_Homo sapiens_hsa034501.48445397
21p53 signaling pathway_Homo sapiens_hsa041151.43891941
22Amoebiasis_Homo sapiens_hsa051461.42691442
23AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.41844480
24Apoptosis_Homo sapiens_hsa042101.41724358
25NF-kappa B signaling pathway_Homo sapiens_hsa040641.40798935
26MicroRNAs in cancer_Homo sapiens_hsa052061.40502383
27Chronic myeloid leukemia_Homo sapiens_hsa052201.38845258
28Osteoclast differentiation_Homo sapiens_hsa043801.38536479
29Pertussis_Homo sapiens_hsa051331.38071950
30Toll-like receptor signaling pathway_Homo sapiens_hsa046201.35909662
31Hematopoietic cell lineage_Homo sapiens_hsa046401.35765055
32Measles_Homo sapiens_hsa051621.35629232
33Renin-angiotensin system_Homo sapiens_hsa046141.29681060
34Mineral absorption_Homo sapiens_hsa049781.26075336
35NOD-like receptor signaling pathway_Homo sapiens_hsa046211.26052755
36Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.24270800
37Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.22417963
38Pentose phosphate pathway_Homo sapiens_hsa000301.21273468
39Renal cell carcinoma_Homo sapiens_hsa052111.21204153
40Hepatitis B_Homo sapiens_hsa051611.20706883
41Pancreatic cancer_Homo sapiens_hsa052121.20457766
42Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.19284180
43Platelet activation_Homo sapiens_hsa046111.18482045
44TGF-beta signaling pathway_Homo sapiens_hsa043501.14841366
45Regulation of actin cytoskeleton_Homo sapiens_hsa048101.14677562
46Tuberculosis_Homo sapiens_hsa051521.14345915
47Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.13261296
48Protein digestion and absorption_Homo sapiens_hsa049741.11088401
49Thyroid cancer_Homo sapiens_hsa052161.09745106
50Viral carcinogenesis_Homo sapiens_hsa052031.09707610
51Intestinal immune network for IgA production_Homo sapiens_hsa046721.07542562
52Influenza A_Homo sapiens_hsa051641.06679861
53Herpes simplex infection_Homo sapiens_hsa051681.06345365
54Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.05560853
55Hippo signaling pathway_Homo sapiens_hsa043901.03490194
56Vibrio cholerae infection_Homo sapiens_hsa051101.03056814
57Jak-STAT signaling pathway_Homo sapiens_hsa046301.01389686
58RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.98474014
59HTLV-I infection_Homo sapiens_hsa051660.97508048
60Cell cycle_Homo sapiens_hsa041100.96436024
61Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.95647029
62Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.95488937
63Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.95281412
64Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.94910703
65Phagosome_Homo sapiens_hsa041450.93044125
66Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.92033769
67Tight junction_Homo sapiens_hsa045300.91781812
68Glycosaminoglycan degradation_Homo sapiens_hsa005310.89783795
69Caffeine metabolism_Homo sapiens_hsa002320.89043288
70Transcriptional misregulation in cancer_Homo sapiens_hsa052020.88356147
71Non-small cell lung cancer_Homo sapiens_hsa052230.86206139
72PI3K-Akt signaling pathway_Homo sapiens_hsa041510.85490334
73Prostate cancer_Homo sapiens_hsa052150.84983378
74Fructose and mannose metabolism_Homo sapiens_hsa000510.83667249
75Graft-versus-host disease_Homo sapiens_hsa053320.83582270
76Hepatitis C_Homo sapiens_hsa051600.83347805
77Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.82537455
78Pathways in cancer_Homo sapiens_hsa052000.80811223
79Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.78714720
80HIF-1 signaling pathway_Homo sapiens_hsa040660.78580393
81Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.77635382
82Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.75652283
83Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.73927374
84Thyroid hormone signaling pathway_Homo sapiens_hsa049190.73118245
85Acute myeloid leukemia_Homo sapiens_hsa052210.72796606
86Sphingolipid signaling pathway_Homo sapiens_hsa040710.71860738
87Glutathione metabolism_Homo sapiens_hsa004800.71049483
88Dilated cardiomyopathy_Homo sapiens_hsa054140.68965611
89Starch and sucrose metabolism_Homo sapiens_hsa005000.67907723
90Steroid biosynthesis_Homo sapiens_hsa001000.66718604
91Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.66611540
92Colorectal cancer_Homo sapiens_hsa052100.65818144
93Melanoma_Homo sapiens_hsa052180.65742886
94RNA transport_Homo sapiens_hsa030130.64918886
95Allograft rejection_Homo sapiens_hsa053300.64435090
96Chemokine signaling pathway_Homo sapiens_hsa040620.62941343
97Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.61246265
98Rap1 signaling pathway_Homo sapiens_hsa040150.61047714
99Asthma_Homo sapiens_hsa053100.60997058
100Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.60336473
101B cell receptor signaling pathway_Homo sapiens_hsa046620.60206553
102Endometrial cancer_Homo sapiens_hsa052130.59369124
103ErbB signaling pathway_Homo sapiens_hsa040120.59226144
104Sulfur metabolism_Homo sapiens_hsa009200.59170840
105Epstein-Barr virus infection_Homo sapiens_hsa051690.58724045
106Lysosome_Homo sapiens_hsa041420.58024084
107Neurotrophin signaling pathway_Homo sapiens_hsa047220.57479679
108Other glycan degradation_Homo sapiens_hsa005110.57438371
109FoxO signaling pathway_Homo sapiens_hsa040680.56303140
110mTOR signaling pathway_Homo sapiens_hsa041500.55085928
111VEGF signaling pathway_Homo sapiens_hsa043700.54355112
112Selenocompound metabolism_Homo sapiens_hsa004500.54244346
113Galactose metabolism_Homo sapiens_hsa000520.53788768
114Glioma_Homo sapiens_hsa052140.52013614
115Systemic lupus erythematosus_Homo sapiens_hsa053220.51957563
116Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.51739111
117Endocytosis_Homo sapiens_hsa041440.51490244
118N-Glycan biosynthesis_Homo sapiens_hsa005100.50869245
119Staphylococcus aureus infection_Homo sapiens_hsa051500.50710004
120Basal cell carcinoma_Homo sapiens_hsa052170.49850175
121Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.48720609
122Central carbon metabolism in cancer_Homo sapiens_hsa052300.48687987
123Insulin signaling pathway_Homo sapiens_hsa049100.48561134
124Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.48306386
125Sphingolipid metabolism_Homo sapiens_hsa006000.47818238
126Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.46930592
127Prolactin signaling pathway_Homo sapiens_hsa049170.45817726
128Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.44161374
129Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.41928257
130Folate biosynthesis_Homo sapiens_hsa007900.41581738

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »