SLC25A36

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore organization (GO:0006999)3.67670988
2regulation of helicase activity (GO:0051095)3.66837003
3nuclear pore complex assembly (GO:0051292)3.54146699
4monoubiquitinated protein deubiquitination (GO:0035520)3.40656280
5regulation of nuclear cell cycle DNA replication (GO:0033262)3.33949279
6histone H4-K12 acetylation (GO:0043983)3.28908447
7neural tube formation (GO:0001841)3.22938158
8IMP biosynthetic process (GO:0006188)3.20271545
9regulation of RNA export from nucleus (GO:0046831)3.15415160
10epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.14292192
11somatic hypermutation of immunoglobulin genes (GO:0016446)3.08056628
12somatic diversification of immune receptors via somatic mutation (GO:0002566)3.08056628
13positive regulation of dendritic spine morphogenesis (GO:0061003)3.04048848
14mitotic metaphase plate congression (GO:0007080)2.98087567
15negative regulation of neurotransmitter secretion (GO:0046929)2.97763876
16cytoplasmic mRNA processing body assembly (GO:0033962)2.96672099
17paraxial mesoderm development (GO:0048339)2.93320557
18ribosomal small subunit assembly (GO:0000028)2.91919868
19pyrimidine dimer repair (GO:0006290)2.90762907
20nucleobase biosynthetic process (GO:0046112)2.89550840
21protein K6-linked ubiquitination (GO:0085020)2.88526193
22intraciliary transport (GO:0042073)2.86096190
23positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.85281778
24positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.85281778
25positive regulation of mitotic sister chromatid separation (GO:1901970)2.85281778
26replication fork processing (GO:0031297)2.84966913
27purine nucleobase biosynthetic process (GO:0009113)2.84599853
28regulation of gene silencing by RNA (GO:0060966)2.84170761
29regulation of posttranscriptional gene silencing (GO:0060147)2.84170761
30regulation of gene silencing by miRNA (GO:0060964)2.84170761
31microtubule anchoring (GO:0034453)2.83714015
32negative regulation of DNA repair (GO:0045738)2.82692098
33pore complex assembly (GO:0046931)2.80480622
34regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.78838947
35metaphase plate congression (GO:0051310)2.78023400
36presynaptic membrane assembly (GO:0097105)2.77397140
37DNA topological change (GO:0006265)2.77204768
38histone H4-K5 acetylation (GO:0043981)2.76182021
39histone H4-K8 acetylation (GO:0043982)2.76182021
40intra-S DNA damage checkpoint (GO:0031573)2.75425622
41interkinetic nuclear migration (GO:0022027)2.74899216
42poly(A)+ mRNA export from nucleus (GO:0016973)2.72024346
43maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.69439289
44regulation of telomere maintenance via telomerase (GO:0032210)2.68531929
45kinetochore organization (GO:0051383)2.66300758
46negative regulation of DNA-dependent DNA replication (GO:2000104)2.66208131
47DNA replication initiation (GO:0006270)2.65633325
48histone H3-K9 methylation (GO:0051567)2.65035749
49cilium or flagellum-dependent cell motility (GO:0001539)2.63203121
50presynaptic membrane organization (GO:0097090)2.59994666
51regulation of centriole replication (GO:0046599)2.59990435
52regulation of histone H3-K27 methylation (GO:0061085)2.58360392
53regulation of growth hormone secretion (GO:0060123)2.57366971
54chromatin remodeling at centromere (GO:0031055)2.56580887
55negative regulation of histone methylation (GO:0031061)2.55787915
56gastrulation with mouth forming second (GO:0001702)2.51349654
57CENP-A containing nucleosome assembly (GO:0034080)2.50877052
58regulation of pigment cell differentiation (GO:0050932)2.50426176
59kinetochore assembly (GO:0051382)2.49973262
60reciprocal meiotic recombination (GO:0007131)2.49712730
61reciprocal DNA recombination (GO:0035825)2.49712730
62limb bud formation (GO:0060174)2.49232404
63replicative senescence (GO:0090399)2.49033766
64regulation of DNA endoreduplication (GO:0032875)2.48669611
65negative regulation of cytosolic calcium ion concentration (GO:0051481)2.47410009
66IMP metabolic process (GO:0046040)2.47108485
67histone arginine methylation (GO:0034969)2.46771993
68spindle checkpoint (GO:0031577)2.44716270
69regulation of non-canonical Wnt signaling pathway (GO:2000050)2.43612188
70somite development (GO:0061053)2.43610389
71regulation of mRNA splicing, via spliceosome (GO:0048024)2.43420921
72embryonic retina morphogenesis in camera-type eye (GO:0060059)2.43330244
73regulation of histone H3-K9 methylation (GO:0051570)2.41822524
74DNA double-strand break processing (GO:0000729)2.40591367
75regulation of mitotic sister chromatid separation (GO:0010965)2.40507958
76regulation of mitotic sister chromatid segregation (GO:0033047)2.40507958
77regulation of sister chromatid segregation (GO:0033045)2.40507958
78spermatid nucleus differentiation (GO:0007289)2.39512760
79viral mRNA export from host cell nucleus (GO:0046784)2.39476702
80central nervous system projection neuron axonogenesis (GO:0021952)2.39288669
81histone H3-K9 demethylation (GO:0033169)2.39241644
82establishment of chromosome localization (GO:0051303)2.38808060
83mRNA export from nucleus (GO:0006406)2.37144171
84regulation of telomere maintenance (GO:0032204)2.36467911
85histone mRNA catabolic process (GO:0071044)2.36445101
86mitotic spindle checkpoint (GO:0071174)2.36334511
87epithelial cell differentiation involved in kidney development (GO:0035850)2.36026920
88mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686)2.35804951
89positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:19021102.35804951
90otic vesicle formation (GO:0030916)2.35693642
91regulation of mitotic metaphase/anaphase transition (GO:0030071)2.35627998
92spindle assembly checkpoint (GO:0071173)2.35115446
93embryonic camera-type eye morphogenesis (GO:0048596)2.34763135
94positive regulation of RNA splicing (GO:0033120)2.34538603
95negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.34509595
96negative regulation of translation, ncRNA-mediated (GO:0040033)2.34509595
97regulation of translation, ncRNA-mediated (GO:0045974)2.34509595
98DNA synthesis involved in DNA repair (GO:0000731)2.34271962
99RNA export from nucleus (GO:0006405)2.34263091
100positive regulation of SMAD protein import into nucleus (GO:0060391)2.33476934
101histone H2A acetylation (GO:0043968)2.33040628
102DNA replication-independent nucleosome organization (GO:0034724)2.32261467
103DNA replication-independent nucleosome assembly (GO:0006336)2.32261467
104snRNA processing (GO:0016180)2.32113361
105mitotic sister chromatid cohesion (GO:0007064)2.30697587
106regulation of spindle organization (GO:0090224)2.30524711
107regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.29853013
108embryonic foregut morphogenesis (GO:0048617)2.29786405
109mitotic spindle assembly checkpoint (GO:0007094)2.29428464
110pituitary gland development (GO:0021983)2.28315278
111regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.28204920
112regulation of transforming growth factor beta2 production (GO:0032909)2.27815286
113regulation of nucleobase-containing compound transport (GO:0032239)2.27722996
114stress granule assembly (GO:0034063)2.27709970
115negative regulation of mitotic sister chromatid separation (GO:2000816)2.26915896
116negative regulation of mitotic sister chromatid segregation (GO:0033048)2.26915896
117negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.26915896
118negative regulation of sister chromatid segregation (GO:0033046)2.26915896
119mitotic recombination (GO:0006312)2.26749713
120maturation of 5.8S rRNA (GO:0000460)2.26405417
121establishment of protein localization to Golgi (GO:0072600)2.25476653
122negative regulation of chromosome segregation (GO:0051985)2.25394615
123DNA strand renaturation (GO:0000733)2.25047545
124protein localization to cilium (GO:0061512)2.24494792
125phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.23877976
126regulation of cAMP-dependent protein kinase activity (GO:2000479)2.23677249
127positive regulation of developmental pigmentation (GO:0048087)2.23420385
128nucleus localization (GO:0051647)2.23261959
129regulation of mitotic spindle organization (GO:0060236)2.22489155
130regulation of centrosome duplication (GO:0010824)2.22351638
131cullin deneddylation (GO:0010388)2.21815102
132negative regulation of intracellular estrogen receptor signaling pathway (GO:0033147)2.21810398
133negative regulation of DNA recombination (GO:0045910)2.21279262
134cilium movement (GO:0003341)2.21073176
135mismatch repair (GO:0006298)2.20885426
136peptidyl-lysine trimethylation (GO:0018023)2.20205037
137meiotic chromosome segregation (GO:0045132)2.19954608
138protein localization to kinetochore (GO:0034501)2.19344055
139mRNA transport (GO:0051028)2.18901065
140mRNA splice site selection (GO:0006376)2.18327248
141somite rostral/caudal axis specification (GO:0032525)2.18298920
142telomere maintenance via recombination (GO:0000722)2.18234692
143sister chromatid cohesion (GO:0007062)2.18138473
144pre-miRNA processing (GO:0031054)2.17930641
145regulation of stem cell maintenance (GO:2000036)2.17808936
146negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.17565798
147telomere maintenance (GO:0000723)2.17119058
148protein targeting to Golgi (GO:0000042)2.17085896
149negative regulation of calcium ion-dependent exocytosis (GO:0045955)2.16278402
150definitive hemopoiesis (GO:0060216)2.16224076
151negative regulation of neurotransmitter transport (GO:0051589)2.15965435
152mitotic nuclear envelope disassembly (GO:0007077)2.15449924
153telomere maintenance via semi-conservative replication (GO:0032201)2.15380634
154histone H3-K4 trimethylation (GO:0080182)2.15380276
155neuron recognition (GO:0008038)2.15282688
156lateral sprouting from an epithelium (GO:0060601)2.14545837
157retrograde transport, vesicle recycling within Golgi (GO:0000301)2.14520206
158positive regulation of DNA-dependent DNA replication (GO:2000105)2.14480650
159mitotic chromosome condensation (GO:0007076)2.14248353
160transcription initiation from RNA polymerase I promoter (GO:0006361)2.14225385
161epithelial cilium movement (GO:0003351)2.14165076
162coronary vasculature morphogenesis (GO:0060977)2.13062319
163neuron cell-cell adhesion (GO:0007158)2.11912514
164establishment of mitochondrion localization (GO:0051654)2.11420156
165regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.11031896
166head development (GO:0060322)2.10419468
167axonal fasciculation (GO:0007413)2.10312838
168regulation of DNA-templated transcription, initiation (GO:2000142)2.09734355
169peptidyl-lysine methylation (GO:0018022)2.09074014
170histone H3-K9 modification (GO:0061647)2.08646219
171pyrimidine nucleobase catabolic process (GO:0006208)2.08547410
172apical protein localization (GO:0045176)2.07238862
173histone H4-K16 acetylation (GO:0043984)2.05402435
174positive regulation of cell size (GO:0045793)2.04241879
175negative regulation of RNA splicing (GO:0033119)2.04153240
176dendrite morphogenesis (GO:0048813)2.04022930
177morphogenesis of an epithelial sheet (GO:0002011)2.04009687
178cardiac myofibril assembly (GO:0055003)2.03410216
179cilium organization (GO:0044782)2.03347504
180positive regulation of growth hormone secretion (GO:0060124)2.03210952
181cilium assembly (GO:0042384)2.02462892
182hindbrain development (GO:0030902)2.02213960
183negative regulation of mRNA splicing, via spliceosome (GO:0048025)2.02172764
184body morphogenesis (GO:0010171)2.00798902
185lung-associated mesenchyme development (GO:0060484)2.00717763
186establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.00181302
187mitochondrion transport along microtubule (GO:0047497)2.00181302
188cerebral cortex radially oriented cell migration (GO:0021799)1.99630362

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.77238826
2HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.55537317
3SALL1_21062744_ChIP-ChIP_HESCs_Human3.51424576
4E2F4_17652178_ChIP-ChIP_JURKAT_Human3.17518392
5* KDM5B_21448134_ChIP-Seq_MESCs_Mouse3.17201461
6MYC_18555785_ChIP-Seq_MESCs_Mouse2.96653524
7RBPJ_22232070_ChIP-Seq_NCS_Mouse2.89027372
8TAF15_26573619_Chip-Seq_HEK293_Human2.69564823
9IGF1R_20145208_ChIP-Seq_DFB_Human2.51905549
10KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.51260413
11KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.51260413
12KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.51260413
13TP63_19390658_ChIP-ChIP_HaCaT_Human2.47481671
14FOXM1_23109430_ChIP-Seq_U2OS_Human2.42867446
15KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.25153687
16YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.21672731
17ZFP57_27257070_Chip-Seq_ESCs_Mouse2.20859483
18CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.17883096
19* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.16679917
20FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.13350098
21PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.12542275
22MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.12357439
23NELFA_20434984_ChIP-Seq_ESCs_Mouse2.11077925
24FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.08901078
25* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.05340306
26ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.99558705
27HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.98854374
28* ELK1_19687146_ChIP-ChIP_HELA_Human1.93530121
29WT1_19549856_ChIP-ChIP_CCG9911_Human1.91979721
30* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.88323900
31ZNF274_21170338_ChIP-Seq_K562_Hela1.85089465
32EST1_17652178_ChIP-ChIP_JURKAT_Human1.83844410
33RNF2_27304074_Chip-Seq_NSC_Mouse1.82444173
34CTBP2_25329375_ChIP-Seq_LNCAP_Human1.81561000
35MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.80345054
36NANOG_18555785_ChIP-Seq_MESCs_Mouse1.79613458
37* SOX2_18555785_ChIP-Seq_MESCs_Mouse1.79044204
38* E2F1_21310950_ChIP-Seq_MCF-7_Human1.78565576
39FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.76829396
40P300_19829295_ChIP-Seq_ESCs_Human1.72027455
41PIAS1_25552417_ChIP-Seq_VCAP_Human1.69020298
42POU5F1_16153702_ChIP-ChIP_HESCs_Human1.68895673
43POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.68765075
44VDR_23849224_ChIP-Seq_CD4+_Human1.66772922
45* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.66489552
46GABP_17652178_ChIP-ChIP_JURKAT_Human1.66247401
47MYCN_18555785_ChIP-Seq_MESCs_Mouse1.64796160
48FUS_26573619_Chip-Seq_HEK293_Human1.62703989
49POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.62017936
50VDR_22108803_ChIP-Seq_LS180_Human1.61249137
51HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.60995505
52PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.60838093
53* SMAD4_21799915_ChIP-Seq_A2780_Human1.59773787
54SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.59230249
55TOP2B_26459242_ChIP-Seq_MCF-7_Human1.57580343
56CBX2_27304074_Chip-Seq_ESCs_Mouse1.57008230
57SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.57001954
58EGR1_19374776_ChIP-ChIP_THP-1_Human1.56844164
59JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.56201147
60SMAD3_21741376_ChIP-Seq_EPCs_Human1.54869082
61EZH2_22144423_ChIP-Seq_EOC_Human1.52949289
62* MYC_18358816_ChIP-ChIP_MESCs_Mouse1.52127010
63OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.50752254
64* SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.49377989
65CDX2_19796622_ChIP-Seq_MESCs_Mouse1.49208011
66* TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.48523348
67STAT3_23295773_ChIP-Seq_U87_Human1.48460851
68HOXB4_20404135_ChIP-ChIP_EML_Mouse1.48215880
69* NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.47060489
70POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.44204571
71TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.44204571
72ELF1_17652178_ChIP-ChIP_JURKAT_Human1.43638795
73TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.42881720
74* TCF3_18692474_ChIP-Seq_MESCs_Mouse1.42659672
75DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.42101954
76CTBP1_25329375_ChIP-Seq_LNCAP_Human1.41838079
77* HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.41719299
78STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.41649103
79TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.41449228
80GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.41358386
81AR_21572438_ChIP-Seq_LNCaP_Human1.41345945
82BMI1_23680149_ChIP-Seq_NPCS_Mouse1.41245010
83PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.40906924
84* RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.40264515
85ER_23166858_ChIP-Seq_MCF-7_Human1.39764884
86E2F1_18555785_ChIP-Seq_MESCs_Mouse1.39595473
87THAP11_20581084_ChIP-Seq_MESCs_Mouse1.37273491
88MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.36947781
89* EWS_26573619_Chip-Seq_HEK293_Human1.36655813
90* SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.35758874
91CIITA_25753668_ChIP-Seq_RAJI_Human1.35180717
92MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.33545291
93FOXP3_21729870_ChIP-Seq_TREG_Human1.33470762
94SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.33040745
95NANOG_18555785_Chip-Seq_ESCs_Mouse1.32266781
96SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.31078445
97FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.30124929
98SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.29294696
99* NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.28630986
100* ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.27326919
101TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.26858693
102CREB1_15753290_ChIP-ChIP_HEK293T_Human1.26117775
103PADI4_21655091_ChIP-ChIP_MCF-7_Human1.25704342
104ETS1_20019798_ChIP-Seq_JURKAT_Human1.25623316
105TCF4_23295773_ChIP-Seq_U87_Human1.24805580
106TTF2_22483619_ChIP-Seq_HELA_Human1.24525180
107NR3C1_21868756_ChIP-Seq_MCF10A_Human1.23478818
108NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.22994741
109TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.22895017
110SOX9_26525672_Chip-Seq_HEART_Mouse1.21799887
111* FOXM1_26456572_ChIP-Seq_MCF-7_Human1.21733436
112POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.21464274
113UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.19721954
114* YAP1_20516196_ChIP-Seq_MESCs_Mouse1.19629133
115EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.18802561
116TCF3_18692474_ChIP-Seq_MEFs_Mouse1.18127888
117ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.17923721
118XRN2_22483619_ChIP-Seq_HELA_Human1.17131420
119* ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.16892891
120FLI1_27457419_Chip-Seq_LIVER_Mouse1.16634052
121SOX2_16153702_ChIP-ChIP_HESCs_Human1.14299467
122RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.13831974
123LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.13399082
124IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.13297623
125CBP_20019798_ChIP-Seq_JUKART_Human1.13297623
126* TFEB_21752829_ChIP-Seq_HELA_Human1.13059015
127ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.12666048
128* ZNF217_24962896_ChIP-Seq_MCF-7_Human1.12496494
129* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.12002768
130* RUNX2_22187159_ChIP-Seq_PCA_Human1.11068604
131NANOG_16153702_ChIP-ChIP_HESCs_Human1.10588580
132TCF4_18268006_ChIP-ChIP_LS174T_Human1.10205391
133CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.09766324
134CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.09574933
135EZH2_27304074_Chip-Seq_ESCs_Mouse1.08976033
136GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.08865074
137AR_25329375_ChIP-Seq_VCAP_Human1.08715298
138E2F1_18555785_Chip-Seq_ESCs_Mouse1.08689359
139SRF_21415370_ChIP-Seq_HL-1_Mouse1.07806503
140SOX2_21211035_ChIP-Seq_LN229_Gbm1.06378516
141DCP1A_22483619_ChIP-Seq_HELA_Human1.06009542
142ERG_20887958_ChIP-Seq_HPC-7_Mouse1.05596328
143TBX3_20139965_ChIP-Seq_ESCs_Mouse1.04599161
144* POU3F2_20337985_ChIP-ChIP_501MEL_Human1.04313218
145TBX3_20139965_ChIP-Seq_MESCs_Mouse1.04269104
146YY1_21170310_ChIP-Seq_MESCs_Mouse1.03834874
147TAL1_26923725_Chip-Seq_HPCs_Mouse1.03201035
148CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.03128619
149CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.03091060
150PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.02724678
151IRF1_19129219_ChIP-ChIP_H3396_Human1.02129906
152FLI1_21867929_ChIP-Seq_TH2_Mouse1.02102595
153KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.01567678
154GABP_19822575_ChIP-Seq_HepG2_Human1.00212379
155NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.00065141
156NRF2_20460467_ChIP-Seq_MEFs_Mouse1.00065141
157P53_22387025_ChIP-Seq_ESCs_Mouse0.99398889
158PCGF2_27294783_Chip-Seq_ESCs_Mouse0.98775637
159ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.98593437
160TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse0.98044702
161EP300_21415370_ChIP-Seq_HL-1_Mouse0.97887203
162SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.97791165
163EZH2_27294783_Chip-Seq_NPCs_Mouse0.97541955
164ISL1_27105846_Chip-Seq_CPCs_Mouse0.97290082
165CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.96683459
166* POU5F1_18347094_ChIP-ChIP_MESCs_Mouse0.94611659
167* NANOG_21062744_ChIP-ChIP_HESCs_Human0.91900831
168BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse0.90124016
169GATA4_21415370_ChIP-Seq_HL-1_Mouse0.89140064
170* TCF3_18347094_ChIP-ChIP_MESCs_Mouse0.88789574
171* NANOG_18347094_ChIP-ChIP_MESCs_Mouse0.87969544
172AR_21909140_ChIP-Seq_LNCAP_Human0.84727335
173PKCTHETA_26484144_Chip-Seq_BREAST_Human0.84591857
174GBX2_23144817_ChIP-Seq_PC3_Human0.83543524

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003123_paternal_imprinting3.11091427
2MP0003121_genomic_imprinting2.98947278
3MP0003787_abnormal_imprinting2.87523340
4MP0008057_abnormal_DNA_replication2.58771744
5MP0008058_abnormal_DNA_repair2.55908456
6MP0010094_abnormal_chromosome_stability2.55058461
7MP0003122_maternal_imprinting2.39483399
8MP0003111_abnormal_nucleus_morphology2.11246843
9MP0001188_hyperpigmentation2.08826138
10MP0003077_abnormal_cell_cycle2.06548648
11MP0003693_abnormal_embryo_hatching2.03761924
12MP0005171_absent_coat_pigmentation2.02166078
13MP0000516_abnormal_urinary_system2.01365281
14MP0005367_renal/urinary_system_phenotyp2.01365281
15MP0000778_abnormal_nervous_system1.97424248
16MP0008007_abnormal_cellular_replicative1.97293074
17MP0006292_abnormal_olfactory_placode1.94108158
18MP0003880_abnormal_central_pattern1.88427090
19MP0008877_abnormal_DNA_methylation1.83028659
20MP0004957_abnormal_blastocyst_morpholog1.76231877
21MP0003786_premature_aging1.75748034
22MP0009697_abnormal_copulation1.70134699
23MP0005423_abnormal_somatic_nervous1.67582648
24MP0003941_abnormal_skin_development1.65449821
25MP0001984_abnormal_olfaction1.61111414
26MP0003890_abnormal_embryonic-extraembry1.52981030
27MP0003567_abnormal_fetal_cardiomyocyte1.52649768
28MP0002009_preneoplasia1.51282276
29MP0000015_abnormal_ear_pigmentation1.50614772
30MP0002938_white_spotting1.49034819
31MP0002163_abnormal_gland_morphology1.46111630
32MP0001293_anophthalmia1.44938632
33MP0000383_abnormal_hair_follicle1.43126574
34MP0004133_heterotaxia1.42044127
35MP0004084_abnormal_cardiac_muscle1.40699514
36MP0000372_irregular_coat_pigmentation1.38699644
37MP0004215_abnormal_myocardial_fiber1.38304070
38MP0000569_abnormal_digit_pigmentation1.36893145
39MP0002233_abnormal_nose_morphology1.35008664
40MP0009703_decreased_birth_body1.34059176
41MP0003119_abnormal_digestive_system1.33942193
42MP0000678_abnormal_parathyroid_gland1.31643443
43MP0001299_abnormal_eye_distance/1.31464907
44MP0002697_abnormal_eye_size1.30095867
45MP0010030_abnormal_orbit_morphology1.29226508
46MP0001529_abnormal_vocalization1.28878878
47MP0003861_abnormal_nervous_system1.27196014
48MP0005187_abnormal_penis_morphology1.27062193
49MP0004859_abnormal_synaptic_plasticity1.25691639
50MP0002877_abnormal_melanocyte_morpholog1.24629972
51MP0003136_yellow_coat_color1.23720655
52MP0004270_analgesia1.22111278
53MP0000371_diluted_coat_color1.21908947
54MP0002277_abnormal_respiratory_mucosa1.20330437
55MP0002160_abnormal_reproductive_system1.19376340
56MP0005499_abnormal_olfactory_system1.19178202
57MP0005394_taste/olfaction_phenotype1.19178202
58MP0003315_abnormal_perineum_morphology1.16897293
59MP0002102_abnormal_ear_morphology1.16859785
60MP0000350_abnormal_cell_proliferation1.16405009
61MP0002822_catalepsy1.15065205
62MP0002084_abnormal_developmental_patter1.14931273
63MP0000566_synostosis1.14917149
64MP0000955_abnormal_spinal_cord1.14775265
65MP0010307_abnormal_tumor_latency1.13881659
66MP0005248_abnormal_Harderian_gland1.13637901
67MP0002085_abnormal_embryonic_tissue1.13321882
68MP0010352_gastrointestinal_tract_polyps1.13165661
69MP0000537_abnormal_urethra_morphology1.12746086
70MP0005380_embryogenesis_phenotype1.12232201
71MP0001672_abnormal_embryogenesis/_devel1.12232201
72MP0005503_abnormal_tendon_morphology1.12103126
73MP0002184_abnormal_innervation1.11681088
74MP0002638_abnormal_pupillary_reflex1.10558334
75MP0002075_abnormal_coat/hair_pigmentati1.10519394
76MP0000049_abnormal_middle_ear1.09428308
77MP0008932_abnormal_embryonic_tissue1.09363252
78MP0001186_pigmentation_phenotype1.08232229
79MP0001486_abnormal_startle_reflex1.07401574
80MP0004197_abnormal_fetal_growth/weight/1.06697586
81MP0002234_abnormal_pharynx_morphology1.05567273
82MP0003937_abnormal_limbs/digits/tail_de1.03034879
83MP0008789_abnormal_olfactory_epithelium1.02974954
84MP0010678_abnormal_skin_adnexa1.02684170
85MP0001697_abnormal_embryo_size1.02662928
86MP0003984_embryonic_growth_retardation1.02052066
87MP0002088_abnormal_embryonic_growth/wei1.01561421
88MP0003221_abnormal_cardiomyocyte_apopto1.01513006
89MP0002653_abnormal_ependyma_morphology1.01463254
90MP0002095_abnormal_skin_pigmentation1.00339646
91MP0001346_abnormal_lacrimal_gland0.99397520
92MP0003942_abnormal_urinary_system0.99077212
93MP0006072_abnormal_retinal_apoptosis0.98617368
94MP0005379_endocrine/exocrine_gland_phen0.98225955
95MP0001286_abnormal_eye_development0.98182677
96MP0003283_abnormal_digestive_organ0.97942478
97MP0004924_abnormal_behavior0.97750002
98MP0005386_behavior/neurological_phenoty0.97750002
99MP0003115_abnormal_respiratory_system0.97629244
100MP0004264_abnormal_extraembryonic_tissu0.97113584
101MP0002086_abnormal_extraembryonic_tissu0.96802547
102MP0003935_abnormal_craniofacial_develop0.95894622
103MP0005174_abnormal_tail_pigmentation0.94926455
104MP0002081_perinatal_lethality0.94268889
105MP0000681_abnormal_thyroid_gland0.93965216
106MP0002210_abnormal_sex_determination0.93330571
107MP0002152_abnormal_brain_morphology0.92801546
108MP0003385_abnormal_body_wall0.92518576
109MP0009672_abnormal_birth_weight0.92179727
110MP0002751_abnormal_autonomic_nervous0.91965512
111MP0003635_abnormal_synaptic_transmissio0.91780781
112MP0002396_abnormal_hematopoietic_system0.90340729
113MP0002177_abnormal_outer_ear0.89976642
114MP0002114_abnormal_axial_skeleton0.89902755
115MP0003938_abnormal_ear_development0.89541652
116MP0000432_abnormal_head_morphology0.88729411
117MP0005389_reproductive_system_phenotype0.87254115
118MP0006276_abnormal_autonomic_nervous0.86287031
119MP0002557_abnormal_social/conspecific_i0.86203851
120MP0003755_abnormal_palate_morphology0.86078699
121MP0001340_abnormal_eyelid_morphology0.85541772
122MP0001502_abnormal_circadian_rhythm0.85372824
123MP0002249_abnormal_larynx_morphology0.85190575
124MP0001730_embryonic_growth_arrest0.84808538
125MP0002092_abnormal_eye_morphology0.84284818
126MP0008995_early_reproductive_senescence0.84264162
127MP0001145_abnormal_male_reproductive0.84058901
128MP0000428_abnormal_craniofacial_morphol0.83497626
129MP0002132_abnormal_respiratory_system0.82814619
130MP0005645_abnormal_hypothalamus_physiol0.82426991
131MP0000462_abnormal_digestive_system0.82270038
132MP0000631_abnormal_neuroendocrine_gland0.81754831
133MP0004808_abnormal_hematopoietic_stem0.81217833
134MP0002080_prenatal_lethality0.80931963
135MP0002882_abnormal_neuron_morphology0.80897085
136MP0000613_abnormal_salivary_gland0.80519074
137MP0009046_muscle_twitch0.79786745
138MP0005391_vision/eye_phenotype0.79587832
139MP0010630_abnormal_cardiac_muscle0.79435218
140MP0005220_abnormal_exocrine_pancreas0.79373402
141MP0001919_abnormal_reproductive_system0.79371431
142MP0008961_abnormal_basal_metabolism0.79334138
143MP0009780_abnormal_chondrocyte_physiolo0.78262116
144MP0010386_abnormal_urinary_bladder0.77471061
145MP0000534_abnormal_ureter_morphology0.77436850
146MP0000490_abnormal_crypts_of0.77379410
147MP0000313_abnormal_cell_death0.76687548
148MP0001177_atelectasis0.75174057
149MP0001485_abnormal_pinna_reflex0.74283164
150MP0002111_abnormal_tail_morphology0.73473960
151MP0002116_abnormal_craniofacial_bone0.73234807

Predicted human phenotypes

RankGene SetZ-score
1Neoplasm of the adrenal cortex (HP:0100641)3.15151510
2Decreased circulating renin level (HP:0003351)3.09962785
3Hypothermia (HP:0002045)3.09796501
4Hyperactive renin-angiotensin system (HP:0000841)2.88433277
5Chromosomal breakage induced by crosslinking agents (HP:0003221)2.82260321
6Spinal muscular atrophy (HP:0007269)2.81253908
7Birth length less than 3rd percentile (HP:0003561)2.80341922
8Nephroblastoma (Wilms tumor) (HP:0002667)2.77423038
9Chromsome breakage (HP:0040012)2.75796189
10Embryonal renal neoplasm (HP:0011794)2.65564809
11Colon cancer (HP:0003003)2.53196038
12Type I transferrin isoform profile (HP:0003642)2.50170774
13Abnormality of the labia minora (HP:0012880)2.49232839
14Medulloblastoma (HP:0002885)2.46516238
15Midline defect of the nose (HP:0004122)2.45310477
16Drooling (HP:0002307)2.44530475
17Meckel diverticulum (HP:0002245)2.43538932
18Hyperaldosteronism (HP:0000859)2.43330988
19Nephronophthisis (HP:0000090)2.36783261
20Abnormality of chromosome stability (HP:0003220)2.36514304
21Heterotopia (HP:0002282)2.34858073
22Supernumerary spleens (HP:0009799)2.30323229
23Intestinal atresia (HP:0011100)2.29254979
24Abnormality of the ileum (HP:0001549)2.28846356
25Aplasia/Hypoplasia of the uvula (HP:0010293)2.28030794
26Abnormality of cochlea (HP:0000375)2.27826157
27Ependymoma (HP:0002888)2.25106653
28Osteomalacia (HP:0002749)2.23416563
29Abnormal hair whorl (HP:0010721)2.22605782
30Vaginal atresia (HP:0000148)2.22571442
31Shawl scrotum (HP:0000049)2.21901224
32Genital tract atresia (HP:0001827)2.20535813
3311 pairs of ribs (HP:0000878)2.20255236
34Subaortic stenosis (HP:0001682)2.18881641
35Abnormality of the left ventricular outflow tract (HP:0011103)2.18881641
36Hyponatremia (HP:0002902)2.17738770
37Tubulointerstitial nephritis (HP:0001970)2.16237597
38Excessive salivation (HP:0003781)2.12611221
39Acute myeloid leukemia (HP:0004808)2.09938095
40Missing ribs (HP:0000921)2.09827966
41Intestinal fistula (HP:0100819)2.09321133
42Volvulus (HP:0002580)2.08145144
43Renal salt wasting (HP:0000127)2.07710130
44Cutaneous finger syndactyly (HP:0010554)2.06414012
45Neoplasm of the oral cavity (HP:0100649)2.06116116
46Abnormality of the renal medulla (HP:0100957)2.05987114
47Gait imbalance (HP:0002141)2.05826869
48Glioma (HP:0009733)2.05350652
49Rectovaginal fistula (HP:0000143)2.04904062
50Rectal fistula (HP:0100590)2.04904062
51Broad palm (HP:0001169)2.04349623
52Hepatoblastoma (HP:0002884)2.03654174
53Abnormality of the carotid arteries (HP:0005344)2.02517629
54Medial flaring of the eyebrow (HP:0010747)2.00951594
55Abnormality of the fingertips (HP:0001211)2.00902708
56Chronic hepatic failure (HP:0100626)2.00587641
57Acute lymphatic leukemia (HP:0006721)2.00314427
58Abnormality of the preputium (HP:0100587)1.99823086
59Papillary thyroid carcinoma (HP:0002895)1.96309386
60Congenital primary aphakia (HP:0007707)1.94488868
61Patellar aplasia (HP:0006443)1.94330662
62Agnosia (HP:0010524)1.93769236
63Nephrogenic diabetes insipidus (HP:0009806)1.92452359
64Myelodysplasia (HP:0002863)1.92232141
65True hermaphroditism (HP:0010459)1.91209293
66Truncal obesity (HP:0001956)1.91131431
67Abnormality of the pubic bones (HP:0003172)1.90750568
68Anal stenosis (HP:0002025)1.89091120
69Small intestinal stenosis (HP:0012848)1.88396575
70Duodenal stenosis (HP:0100867)1.88396575
71Postaxial foot polydactyly (HP:0001830)1.87879188
72Abnormality of chloride homeostasis (HP:0011422)1.86785943
73Breast hypoplasia (HP:0003187)1.86375540
74Aplasia/hypoplasia of the humerus (HP:0006507)1.85890603
75Poor coordination (HP:0002370)1.85207913
76Short humerus (HP:0005792)1.85047933
77Intellectual disability, moderate (HP:0002342)1.84553078
78Pancreatic fibrosis (HP:0100732)1.83128443
79Protruding tongue (HP:0010808)1.82832528
80Cutaneous syndactyly (HP:0012725)1.81461002
81Spinal cord lesions (HP:0100561)1.81108441
82Syringomyelia (HP:0003396)1.81108441
83Gastrointestinal atresia (HP:0002589)1.79445979
84Hypokalemic alkalosis (HP:0001949)1.79380860
85Absent thumb (HP:0009777)1.79296362
86Omphalocele (HP:0001539)1.77962516
87Cupped ear (HP:0000378)1.77934490
88Micropenis (HP:0000054)1.77303762
89Abnormality of the nasal septum (HP:0000419)1.77278955
90Abnormal lung lobation (HP:0002101)1.76932858
91Aplasia/Hypoplasia of the patella (HP:0006498)1.76428527
92Abnormality of the astrocytes (HP:0100707)1.76014846
93Astrocytoma (HP:0009592)1.76014846
94Neoplasm of the small intestine (HP:0100833)1.75983733
95Pheochromocytoma (HP:0002666)1.74274219
96Diastasis recti (HP:0001540)1.73622978
97Febrile seizures (HP:0002373)1.72973918
98Hyperkalemia (HP:0002153)1.71378652
99Aplastic anemia (HP:0001915)1.71287894
100Cortical dysplasia (HP:0002539)1.69369192
101Myelomeningocele (HP:0002475)1.69274128
102Postaxial hand polydactyly (HP:0001162)1.69141086
103Abnormal pancreas size (HP:0012094)1.68223035
104Abnormal glycosylation (HP:0012345)1.67029427
105Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.67029427
106Abnormal protein N-linked glycosylation (HP:0012347)1.67029427
107Abnormal protein glycosylation (HP:0012346)1.67029427
108Neoplasm of the adrenal gland (HP:0100631)1.66888682
109Bifid tongue (HP:0010297)1.66588363
110Ectopic anus (HP:0004397)1.66556784
111Abnormality of abdominal situs (HP:0011620)1.66505672
112Abdominal situs inversus (HP:0003363)1.66505672
113Abnormality of chromosome segregation (HP:0002916)1.66453344
114Amaurosis fugax (HP:0100576)1.66390964
115Abnormal biliary tract morphology (HP:0012440)1.66324280
116Abnormality of the duodenum (HP:0002246)1.66228104
117Biliary tract neoplasm (HP:0100574)1.65970612
118Increased nuchal translucency (HP:0010880)1.65872221
119Obsessive-compulsive behavior (HP:0000722)1.65774571
120Thyroid carcinoma (HP:0002890)1.65402003
121Hypokalemia (HP:0002900)1.65341277
122Abnormality of the right ventricle (HP:0001707)1.65329100
123Cystic hygroma (HP:0000476)1.65191792
124Supernumerary bones of the axial skeleton (HP:0009144)1.64778161
125Abnormality of the ischium (HP:0003174)1.64405497
126Aplasia/Hypoplasia of the sternum (HP:0006714)1.63800271
127Gonadotropin excess (HP:0000837)1.63529552
128Ectopic kidney (HP:0000086)1.63518014
129Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.63440516
130Hypoplastic labia majora (HP:0000059)1.62689672
131Abnormality of midbrain morphology (HP:0002418)1.62653617
132Molar tooth sign on MRI (HP:0002419)1.62653617
133Renal hypoplasia (HP:0000089)1.61556706
134Lip pit (HP:0100267)1.61323245
135Anophthalmia (HP:0000528)1.61286690
136Abnormality of the renal collecting system (HP:0004742)1.61062800
137Embryonal neoplasm (HP:0002898)1.61061029
138Sloping forehead (HP:0000340)1.61041586
139Facial cleft (HP:0002006)1.60420794
140Aqueductal stenosis (HP:0002410)1.59259026
141Abnormality of DNA repair (HP:0003254)1.59242591
142Thickened helices (HP:0000391)1.59103832
143Abnormality of the anterior horn cell (HP:0006802)1.58456720
144Degeneration of anterior horn cells (HP:0002398)1.58456720
145Pancreatic cysts (HP:0001737)1.56817737
146Deep philtrum (HP:0002002)1.55512698
147Overlapping toe (HP:0001845)1.55431396
148Vertebral arch anomaly (HP:0008438)1.55060065
149Absent eyebrow (HP:0002223)1.53929515
150Narrow forehead (HP:0000341)1.53607279
151Median cleft lip (HP:0000161)1.53603181
152Rimmed vacuoles (HP:0003805)1.53483465
153Supernumerary ribs (HP:0005815)1.53367141
154Abnormality of the incisor (HP:0000676)1.53225913
155Scrotal hypoplasia (HP:0000046)1.53187232
156Rhabdomyosarcoma (HP:0002859)1.52580422
157Bell-shaped thorax (HP:0001591)1.51550390
158Broad alveolar ridges (HP:0000187)1.51467476
159Widely spaced teeth (HP:0000687)1.50984585
160Central scotoma (HP:0000603)1.50907039
161Gastroesophageal reflux (HP:0002020)1.50530445
162Rhinitis (HP:0012384)1.50490648
163Abnormal respiratory epithelium morphology (HP:0012253)1.49717141
164Abnormal respiratory motile cilium morphology (HP:0005938)1.49717141
165Abnormality of the renal cortex (HP:0011035)1.49230477
166Decreased testicular size (HP:0008734)1.48654738
167Facial hemangioma (HP:0000329)1.48574549
168Short foot (HP:0001773)1.48460459
169Broad foot (HP:0001769)1.48066159
170Hyperventilation (HP:0002883)1.47699563
171Limb dystonia (HP:0002451)1.46233767
172Abnormality of the labia majora (HP:0012881)1.45235428
173Bilateral microphthalmos (HP:0007633)1.44120604

Predicted kinase interactions (KEA)

RankGene SetZ-score
1AKT34.14670902
2ZAK3.53847715
3FRK3.45866881
4MKNK23.31475108
5SRPK13.04129281
6MKNK12.82445034
7BRD42.68302353
8MAP3K42.56567763
9MARK12.31198460
10OBSCN2.15579444
11PASK2.14773928
12WEE12.14104435
13EIF2AK32.08413127
14STK38L2.02979001
15ERBB31.97239709
16BRSK21.96190949
17PLK31.90645805
18PNCK1.84634467
19YES11.80929810
20LMTK21.70096905
21VRK11.65863392
22MAP3K61.65665510
23SGK21.65008729
24TNIK1.58334522
25TAOK21.55914208
26STK241.54570372
27PKN21.47586441
28EPHA21.45390672
29ACVR1B1.44977056
30CDC71.43409999
31MAPK131.43086411
32EPHA41.42887717
33TTK1.42055289
34ATR1.41749777
35FGFR21.41144138
36WNK31.38964667
37FLT31.37968609
38PRPF4B1.37272980
39MAP3K101.31201617
40CASK1.29974941
41TSSK61.28530566
42CDK121.26638877
43MAP2K41.25982655
44EIF2AK21.25616739
45CHEK21.24726558
46UHMK11.24603405
47LATS21.23438011
48PLK11.21945544
49RPS6KB21.20433362
50TGFBR11.19204609
51MAPK151.14651321
52CDK81.10154804
53DYRK1A1.07637518
54ATM1.03903580
55CDK71.03171453
56TLK11.01970724
57NEK60.96644360
58MAP3K70.96279499
59TRIM280.95009522
60AURKB0.92941916
61EEF2K0.92491147
62NEK10.91791892
63NTRK20.91198142
64NUAK10.89654640
65CDK190.89308909
66RPS6KA40.88359979
67EIF2AK10.87846203
68NEK20.87173411
69CDK60.85038898
70SGK30.84969218
71STK30.82453099
72RPS6KB10.82129866
73SIK30.80660262
74TYRO30.78806632
75MINK10.78732614
76CHEK10.77534769
77DMPK0.76100465
78PINK10.75552284
79SIK20.75393184
80WNK40.75065277
81BRSK10.73917744
82CAMK1G0.73122918
83CSNK1G20.70426464
84MAP3K30.68181991
85STK390.67872097
86MYLK0.66099774
87CSNK1E0.65174521
88SGK4940.64375129
89SGK2230.64375129
90BUB10.64162060
91BMPR1B0.63490259
92PRKCI0.63365068
93CHUK0.62893979
94LATS10.61875861
95DYRK1B0.61830635
96PRKD30.61481259
97PLK40.61375370
98MAPK100.60544161
99IRAK30.60239932
100PRKG20.59677616
101DYRK30.59667437
102CSNK1G10.58498001
103NTRK30.58236672
104MAP4K20.58101663
105CDK20.57606820
106SGK10.56910348
107SCYL20.56370744
108STK40.56161062
109MST40.56081055
110PIM10.54016842
111KSR10.53966928
112CDK90.53618467
113WNK10.53499948
114EPHA30.51994996
115GSK3B0.51516932
116RET0.51256302
117BMPR20.50319734
118PLK20.50293812
119CSNK1A1L0.50051132
120CDK10.49925021
121FGFR10.48634110
122DYRK20.46692798
123BCR0.46229348
124CDC42BPA0.46109872
125CSNK1D0.44397502
126RPS6KC10.43475572
127RPS6KL10.43475572
128PRKCE0.43439699
129CDK30.43433975
130TXK0.43234034
131PRKDC0.43169869
132ERBB20.43072032
133MAP2K30.42641271
134FGFR30.42279225
135TEC0.41558257
136MAPK140.40566027
137AKT10.40514362
138CSNK2A10.39050614
139NLK0.38515389
140INSRR0.38237404
141MAP2K70.38194379
142CSNK2A20.36582531
143MELK0.36270747
144IRAK40.35653719
145RPS6KA60.34527275

Predicted pathways (KEGG)

RankGene SetZ-score
1Mismatch repair_Homo sapiens_hsa034302.96793997
2DNA replication_Homo sapiens_hsa030302.55196502
3Fanconi anemia pathway_Homo sapiens_hsa034602.42418745
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.35026780
5Homologous recombination_Homo sapiens_hsa034402.27685688
6Cell cycle_Homo sapiens_hsa041102.16279882
7Base excision repair_Homo sapiens_hsa034102.16269173
8Spliceosome_Homo sapiens_hsa030402.13108328
9Nucleotide excision repair_Homo sapiens_hsa034202.12934738
10Basal transcription factors_Homo sapiens_hsa030222.08913509
11RNA transport_Homo sapiens_hsa030132.06503710
12RNA polymerase_Homo sapiens_hsa030202.00433394
13Non-homologous end-joining_Homo sapiens_hsa034501.97274253
14mRNA surveillance pathway_Homo sapiens_hsa030151.96849314
15RNA degradation_Homo sapiens_hsa030181.96029261
16Protein export_Homo sapiens_hsa030601.95231608
17Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.85488379
18Nicotine addiction_Homo sapiens_hsa050331.81648677
19One carbon pool by folate_Homo sapiens_hsa006701.43974390
20Dopaminergic synapse_Homo sapiens_hsa047281.42612480
21Amphetamine addiction_Homo sapiens_hsa050311.42096311
22Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.41317339
23p53 signaling pathway_Homo sapiens_hsa041151.37971827
24Cocaine addiction_Homo sapiens_hsa050301.33490054
25Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.32390981
26Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.31858128
27Circadian entrainment_Homo sapiens_hsa047131.30952239
28Ribosome_Homo sapiens_hsa030101.27785858
29Pyrimidine metabolism_Homo sapiens_hsa002401.23689931
30Glutamatergic synapse_Homo sapiens_hsa047241.22683390
31Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.20724899
32GABAergic synapse_Homo sapiens_hsa047271.20391239
33Axon guidance_Homo sapiens_hsa043601.20225895
34Basal cell carcinoma_Homo sapiens_hsa052171.15018225
35Propanoate metabolism_Homo sapiens_hsa006401.13469183
36Thyroid cancer_Homo sapiens_hsa052161.08604724
37Lysine degradation_Homo sapiens_hsa003101.07776708
38Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.07047337
39Transcriptional misregulation in cancer_Homo sapiens_hsa052021.04580691
40Long-term depression_Homo sapiens_hsa047301.04334283
41Hippo signaling pathway_Homo sapiens_hsa043901.03639694
42Purine metabolism_Homo sapiens_hsa002301.02018217
43Dorso-ventral axis formation_Homo sapiens_hsa043201.00815656
44Dilated cardiomyopathy_Homo sapiens_hsa054141.00159549
45Longevity regulating pathway - mammal_Homo sapiens_hsa042110.99469357
46ErbB signaling pathway_Homo sapiens_hsa040120.99280498
47Adherens junction_Homo sapiens_hsa045200.96732361
48Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.96393246
49Cholinergic synapse_Homo sapiens_hsa047250.96336499
50TGF-beta signaling pathway_Homo sapiens_hsa043500.96306255
51cGMP-PKG signaling pathway_Homo sapiens_hsa040220.95206905
52Choline metabolism in cancer_Homo sapiens_hsa052310.93522745
53N-Glycan biosynthesis_Homo sapiens_hsa005100.92477072
54Morphine addiction_Homo sapiens_hsa050320.91842538
55Gap junction_Homo sapiens_hsa045400.91376745
56Endometrial cancer_Homo sapiens_hsa052130.90306393
57Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.88171271
58cAMP signaling pathway_Homo sapiens_hsa040240.87257639
59Oxytocin signaling pathway_Homo sapiens_hsa049210.86948714
60Wnt signaling pathway_Homo sapiens_hsa043100.86910808
61Herpes simplex infection_Homo sapiens_hsa051680.86653325
62MicroRNAs in cancer_Homo sapiens_hsa052060.86171550
63Oocyte meiosis_Homo sapiens_hsa041140.85734716
64Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.85649666
65Renin secretion_Homo sapiens_hsa049240.85425631
66Hedgehog signaling pathway_Homo sapiens_hsa043400.85219937
67Olfactory transduction_Homo sapiens_hsa047400.84422997
68Prostate cancer_Homo sapiens_hsa052150.83635666
69Epstein-Barr virus infection_Homo sapiens_hsa051690.82971436
70Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.82083098
71Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.81582605
72Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.80958151
73Phototransduction_Homo sapiens_hsa047440.79960772
74Thyroid hormone synthesis_Homo sapiens_hsa049180.79114606
75Colorectal cancer_Homo sapiens_hsa052100.79054126
76Steroid biosynthesis_Homo sapiens_hsa001000.77992159
77Other glycan degradation_Homo sapiens_hsa005110.77139916
78Aldosterone synthesis and secretion_Homo sapiens_hsa049250.76209604
79Viral carcinogenesis_Homo sapiens_hsa052030.75997587
80HTLV-I infection_Homo sapiens_hsa051660.75584818
81AMPK signaling pathway_Homo sapiens_hsa041520.75498463
82Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.75482002
83Taste transduction_Homo sapiens_hsa047420.75092621
84Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.73929154
85Prolactin signaling pathway_Homo sapiens_hsa049170.73393127
86Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.73129453
87Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.72532717
88Alcoholism_Homo sapiens_hsa050340.72209744
89Serotonergic synapse_Homo sapiens_hsa047260.71555936
90Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.71324524
91Type II diabetes mellitus_Homo sapiens_hsa049300.70959245
92Regulation of autophagy_Homo sapiens_hsa041400.70299807
93Glucagon signaling pathway_Homo sapiens_hsa049220.70067905
94Circadian rhythm_Homo sapiens_hsa047100.69644350
95Estrogen signaling pathway_Homo sapiens_hsa049150.68567152
96Renal cell carcinoma_Homo sapiens_hsa052110.68375957
97Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.67886029
98Maturity onset diabetes of the young_Homo sapiens_hsa049500.67015769
99Salivary secretion_Homo sapiens_hsa049700.66897130
100Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.65911358
101Pathways in cancer_Homo sapiens_hsa052000.64338526
102Tight junction_Homo sapiens_hsa045300.63617367
103Calcium signaling pathway_Homo sapiens_hsa040200.60934233
104MAPK signaling pathway_Homo sapiens_hsa040100.60419876
105Selenocompound metabolism_Homo sapiens_hsa004500.59969414
106Insulin signaling pathway_Homo sapiens_hsa049100.59437086
107mTOR signaling pathway_Homo sapiens_hsa041500.58781641
108Melanoma_Homo sapiens_hsa052180.58398270
109Notch signaling pathway_Homo sapiens_hsa043300.58060223
110FoxO signaling pathway_Homo sapiens_hsa040680.56851396
111Small cell lung cancer_Homo sapiens_hsa052220.56634496
112Antigen processing and presentation_Homo sapiens_hsa046120.56488921
113Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.55773890
114Systemic lupus erythematosus_Homo sapiens_hsa053220.53510425
115PI3K-Akt signaling pathway_Homo sapiens_hsa041510.52911051
116Galactose metabolism_Homo sapiens_hsa000520.52353623
117Vibrio cholerae infection_Homo sapiens_hsa051100.52001978
118Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.50411054
119Thyroid hormone signaling pathway_Homo sapiens_hsa049190.50283801
120Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.50089525
121Focal adhesion_Homo sapiens_hsa045100.46571679
122Renin-angiotensin system_Homo sapiens_hsa046140.46434416
123Protein digestion and absorption_Homo sapiens_hsa049740.44940934
124Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.44837072
125Proteasome_Homo sapiens_hsa030500.44641816
126Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.41572087
127Melanogenesis_Homo sapiens_hsa049160.40985996
128SNARE interactions in vesicular transport_Homo sapiens_hsa041300.39127161
129Long-term potentiation_Homo sapiens_hsa047200.37954202
130Measles_Homo sapiens_hsa051620.37443020
131Hepatitis B_Homo sapiens_hsa051610.37273797
132Inositol phosphate metabolism_Homo sapiens_hsa005620.36258342
133Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.35828875
134Neurotrophin signaling pathway_Homo sapiens_hsa047220.35514360
135NF-kappa B signaling pathway_Homo sapiens_hsa040640.35472810
136Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.35142474
137Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.34192851
138HIF-1 signaling pathway_Homo sapiens_hsa040660.33644357
139Phosphatidylinositol signaling system_Homo sapiens_hsa040700.33293546
140Insulin secretion_Homo sapiens_hsa049110.32620831
141Influenza A_Homo sapiens_hsa051640.32533698
142NOD-like receptor signaling pathway_Homo sapiens_hsa046210.31420847
143Regulation of actin cytoskeleton_Homo sapiens_hsa048100.31021538
144Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.30931000
145ECM-receptor interaction_Homo sapiens_hsa045120.30764506
146Autoimmune thyroid disease_Homo sapiens_hsa053200.30610435
147Huntingtons disease_Homo sapiens_hsa050160.30471575
148Chronic myeloid leukemia_Homo sapiens_hsa052200.29714440
149Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.29587375
150Arachidonic acid metabolism_Homo sapiens_hsa005900.29001312

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