ARCHS4

Functional Annotation Prediction

Predicted biological processes (GO)

Rank	Gene Set	Z-score
1	exogenous drug catabolic process (GO:0042738)	9.72325377
2	omega-hydroxylase P450 pathway (GO:0097267)	9.36679954
3	epoxygenase P450 pathway (GO:0019373)	9.17153107
4	L-phenylalanine catabolic process (GO:0006559)	7.57778272
5	erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)	7.57778272
6	L-phenylalanine metabolic process (GO:0006558)	7.27390762
7	erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)	7.27390762
8	aromatic amino acid family catabolic process (GO:0009074)	6.80645974
9	triglyceride-rich lipoprotein particle remodeling (GO:0034370)	6.52360753
10	drug metabolic process (GO:0017144)	6.24290861
11	opsonization (GO:0008228)	6.18463154
12	tryptophan catabolic process (GO:0006569)	6.12727734
13	indole-containing compound catabolic process (GO:0042436)	6.12727734
14	indolalkylamine catabolic process (GO:0046218)	6.12727734
15	kynurenine metabolic process (GO:0070189)	6.03078173
16	bile acid biosynthetic process (GO:0006699)	5.91875526
17	oxidative demethylation (GO:0070989)	5.91280707
18	glyoxylate metabolic process (GO:0046487)	5.77793763
19	regulation of plasminogen activation (GO:0010755)	5.76828308
20	tryptophan metabolic process (GO:0006568)	5.76738825
21	urea metabolic process (GO:0019627)	5.69488174
22	urea cycle (GO:0000050)	5.69488174
23	high-density lipoprotein particle remodeling (GO:0034375)	5.67702234
24	negative regulation of fibrinolysis (GO:0051918)	5.65617827
25	alpha-linolenic acid metabolic process (GO:0036109)	5.64650652
26	ethanol metabolic process (GO:0006067)	5.62835033
27	regulation of fibrinolysis (GO:0051917)	5.44028238
28	sulfur amino acid catabolic process (GO:0000098)	5.41536419
29	protein carboxylation (GO:0018214)	5.39736557
30	peptidyl-glutamic acid carboxylation (GO:0017187)	5.39736557
31	regulation of protein activation cascade (GO:2000257)	5.28474562
32	cysteine metabolic process (GO:0006534)	5.27182973
33	complement activation, alternative pathway (GO:0006957)	5.25777909
34	nitrogen cycle metabolic process (GO:0071941)	5.23358419
35	serine family amino acid catabolic process (GO:0009071)	5.14270619
36	regulation of humoral immune response (GO:0002920)	5.12515255
37	bile acid metabolic process (GO:0008206)	5.07839555
38	killing of cells in other organism involved in symbiotic interaction (GO:0051883)	5.02498142
39	disruption of cells of other organism involved in symbiotic interaction (GO:0051818)	5.02498142
40	regulation of cholesterol esterification (GO:0010872)	5.00305227
41	regulation of triglyceride catabolic process (GO:0010896)	5.00164174
42	reverse cholesterol transport (GO:0043691)	4.96903434
43	aromatic amino acid family metabolic process (GO:0009072)	4.94949766
44	regulation of complement activation (GO:0030449)	4.90303663
45	negative regulation of protein activation cascade (GO:2000258)	4.89048667
46	protein-lipid complex remodeling (GO:0034368)	4.87090270
47	macromolecular complex remodeling (GO:0034367)	4.87090270
48	plasma lipoprotein particle remodeling (GO:0034369)	4.87090270
49	fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)	4.86275274
50	tyrosine metabolic process (GO:0006570)	4.81816170
51	negative regulation of blood coagulation (GO:0030195)	4.78533296
52	negative regulation of hemostasis (GO:1900047)	4.78533296
53	phenylpropanoid metabolic process (GO:0009698)	4.74745009
54	homocysteine metabolic process (GO:0050667)	4.74617816
55	triglyceride homeostasis (GO:0070328)	4.69915275
56	acylglycerol homeostasis (GO:0055090)	4.69915275
57	phospholipid efflux (GO:0033700)	4.68702353
58	alpha-amino acid catabolic process (GO:1901606)	4.65510481
59	negative regulation of cholesterol transport (GO:0032375)	4.65332923
60	negative regulation of sterol transport (GO:0032372)	4.65332923
61	amino-acid betaine metabolic process (GO:0006577)	4.63478333
62	positive regulation of heterotypic cell-cell adhesion (GO:0034116)	4.60952591
63	coenzyme catabolic process (GO:0009109)	4.58861099
64	lysine catabolic process (GO:0006554)	4.54962561
65	lysine metabolic process (GO:0006553)	4.54962561
66	cellular ketone body metabolic process (GO:0046950)	4.48351004
67	plasma lipoprotein particle clearance (GO:0034381)	4.42655092
68	glycine metabolic process (GO:0006544)	4.41089616
69	imidazole-containing compound metabolic process (GO:0052803)	4.34977565
70	bile acid and bile salt transport (GO:0015721)	4.34600518
71	negative regulation of coagulation (GO:0050819)	4.34290534
72	S-adenosylmethionine metabolic process (GO:0046500)	4.34080893
73	indolalkylamine metabolic process (GO:0006586)	4.32959853
74	negative regulation of wound healing (GO:0061045)	4.29598917
75	cellular amino acid catabolic process (GO:0009063)	4.29344466
76	cholesterol efflux (GO:0033344)	4.28122803
77	cellular biogenic amine catabolic process (GO:0042402)	4.23682423
78	amine catabolic process (GO:0009310)	4.23682423
79	cellular modified amino acid catabolic process (GO:0042219)	4.22237725
80	glutamate metabolic process (GO:0006536)	4.21990280
81	positive regulation of hemostasis (GO:1900048)	4.21613040
82	positive regulation of blood coagulation (GO:0030194)	4.21613040
83	cellular glucuronidation (GO:0052695)	4.19113076
84	serine family amino acid metabolic process (GO:0009069)	4.15703825
85	benzene-containing compound metabolic process (GO:0042537)	4.12827756
86	arginine metabolic process (GO:0006525)	4.06302642
87	alkaloid metabolic process (GO:0009820)	4.04469609
88	plasma lipoprotein particle assembly (GO:0034377)	4.03167270
89	fibrinolysis (GO:0042730)	4.02704258
90	dicarboxylic acid biosynthetic process (GO:0043650)	3.99279744
91	serine family amino acid biosynthetic process (GO:0009070)	3.98569269
92	low-density lipoprotein particle remodeling (GO:0034374)	3.98566499
93	acute inflammatory response (GO:0002526)	3.96876418
94	aldehyde catabolic process (GO:0046185)	3.95649594
95	ethanol oxidation (GO:0006069)	3.94148682
96	cofactor catabolic process (GO:0051187)	3.92267568
97	positive regulation of lipoprotein lipase activity (GO:0051006)	3.91463762
98	positive regulation of triglyceride lipase activity (GO:0061365)	3.91463762
99	negative regulation of complement activation (GO:0045916)	3.90448271
100	blood coagulation, intrinsic pathway (GO:0007597)	3.88721095
101	drug catabolic process (GO:0042737)	3.88010108
102	ketone body metabolic process (GO:1902224)	3.87868721
103	negative regulation of lipase activity (GO:0060192)	3.86197564
104	positive regulation of coagulation (GO:0050820)	3.85679436
105	positive regulation of lipid catabolic process (GO:0050996)	3.84334472
106	cholesterol homeostasis (GO:0042632)	3.77050906
107	positive regulation of fatty acid biosynthetic process (GO:0045723)	3.76256883
108	carboxylic acid catabolic process (GO:0046395)	3.75186320
109	organic acid catabolic process (GO:0016054)	3.75186320
110	complement activation, classical pathway (GO:0006958)	3.74338499
111	flavonoid metabolic process (GO:0009812)	3.73191641
112	phospholipid homeostasis (GO:0055091)	3.72356701
113	regulation of bile acid biosynthetic process (GO:0070857)	3.71907607
114	protein activation cascade (GO:0072376)	3.71376995
115	sterol homeostasis (GO:0055092)	3.70587732
116	glucuronate metabolic process (GO:0019585)	3.70201465
117	uronic acid metabolic process (GO:0006063)	3.70201465
118	complement activation (GO:0006956)	3.70005189
119	very-low-density lipoprotein particle assembly (GO:0034379)	3.69962298
120	plasma lipoprotein particle organization (GO:0071827)	3.68216816
121	regulation of cholesterol homeostasis (GO:2000188)	3.64397664
122	acetyl-CoA metabolic process (GO:0006084)	3.61547892
123	protein-lipid complex assembly (GO:0065005)	3.60714410
124	cytolysis (GO:0019835)	3.60436902
125	short-chain fatty acid metabolic process (GO:0046459)	3.59935886
126	regulation of acute inflammatory response (GO:0002673)	3.59662621
127	heme transport (GO:0015886)	3.58364642
128	regulation of apoptotic cell clearance (GO:2000425)	3.57037261
129	acute-phase response (GO:0006953)	3.55270096
130	intestinal cholesterol absorption (GO:0030299)	3.54421102

Predicted upstream transcription factors (ChEA)

Rank	Gene Set	Z-score
1	RXR_22158963_ChIP-Seq_LIVER_Mouse	8.47308693
2	PPARA_22158963_ChIP-Seq_LIVER_Mouse	7.24985084
3	EGR1_23403033_ChIP-Seq_LIVER_Mouse	6.93636611
4	LXR_22158963_ChIP-Seq_LIVER_Mouse	6.53354874
5	FOXO1_23066095_ChIP-Seq_LIVER_Mouse	5.41850403
6	CEBPA_23403033_ChIP-Seq_LIVER_Mouse	5.14217572
7	PPARG_19300518_ChIP-PET_3T3-L1_Mouse	4.94941224
8	NR1I2_20693526_ChIP-Seq_LIVER_Mouse	4.09596374
9	CEBPB_23403033_ChIP-Seq_LIVER_Mouse	4.01416871
10	TCF7L2_21901280_ChIP-Seq_H4IIE_Rat	2.04398624
11	ESR1_17901129_ChIP-ChIP_LIVER_Mouse	12.0511818
12	TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse	1.98320799
13	HNF4A_19761587_ChIP-ChIP_CACO-2_Human	1.95820804
14	FOXA2_19822575_ChIP-Seq_HepG2_Human	1.57980794
15	CLOCK_20551151_ChIP-Seq_293T_Human	1.52225652
16	HTT_18923047_ChIP-ChIP_STHdh_Human	1.47221033
17	GATA1_22025678_ChIP-Seq_K562_Human	1.45643391
18	THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse	1.41591293
19	HNF4A_19822575_ChIP-Seq_HepG2_Human	1.40573064
20	TRIM28_21343339_ChIP-Seq_HEK293_Human	1.28858352
21	STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse	1.24205249
22	RXRA_24833708_ChIP-Seq_LIVER_Mouse	1.24163382
23	STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse	1.17019765
24	ESR1_15608294_ChIP-ChIP_MCF-7_Human	1.12369633
25	MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human	1.04034694
26	ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse	1.01255122
27	IRF1_21803131_ChIP-Seq_MONOCYTES_Human	0.94058979
28	SOX2_27498859_Chip-Seq_STOMACH_Mouse	0.91267856
29	TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse	0.91208805
30	PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse	0.86054716
31	ESRRB_18555785_ChIP-Seq_MESCs_Mouse	0.83140577
32	AUTS2_25519132_ChIP-Seq_293T-REX_Human	0.82919865
33	PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse	0.81640802
34	RARG_19884340_ChIP-ChIP_MEFs_Mouse	0.81108769
35	GATA4_25053715_ChIP-Seq_YYC3_Human	0.79388351
36	BCAT_22108803_ChIP-Seq_LS180_Human	0.78944638
37	GLI1_17442700_ChIP-ChIP_MESCs_Mouse	0.78084974
38	IRF8_22096565_ChIP-ChIP_GC-B_Human	0.78037428
39	SREBP1_19666523_ChIP-Seq_LIVER_Mouse	0.77536431
40	RARA_24833708_ChIP-Seq_LIVER_Mouse	0.76790722
41	ZNF652_21678463_ChIP-ChIP_ZR75-1_Human	0.75472764
42	SREBP2_21459322_ChIP-Seq_LIVER_Mouse	0.74823953
43	NR0B1_18358816_ChIP-ChIP_MESCs_Mouse	0.74034294
44	SOX2_21211035_ChIP-Seq_LN229_Human	0.72971076
45	KAP1_22055183_ChIP-Seq_ESCs_Mouse	0.72555937
46	CDX2_21074721_ChIP-Seq_CACO-2_Mouse	0.70917462
47	BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human	0.70507929
48	ESR2_21235772_ChIP-Seq_MCF-7_Human	0.69745894
49	HNFA_21074721_ChIP-Seq_CACO-2_Human	0.68332192
50	SMC4_20622854_ChIP-Seq_HELA_Human	0.68119668
51	CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse	0.67456269
52	CTCF_27219007_Chip-Seq_Bcells_Human	0.67386507
53	Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse	0.66881514
54	RARB_24833708_ChIP-Seq_LIVER_Mouse	0.66767865
55	RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human	0.65990199
56	STAT3_1855785_ChIP-Seq_MESCs_Mouse	0.65488704
57	NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human	0.65461682
58	E2F1_20622854_ChIP-Seq_HELA_Human	0.65417036
59	RAC3_21632823_ChIP-Seq_H3396_Human	0.65024806
60	ELF1_20517297_ChIP-Seq_JURKAT_Human	0.64934171
61	BMI1_19503595_ChIP-Seq_MEFsC_Mouse	0.64383014
62	ZNF263_19887448_ChIP-Seq_K562_Human	0.64326355
63	AR_21915096_ChIP-Seq_LNCaP-1F5_Human	0.63948287
64	PHF8_20622853_ChIP-Seq_HELA_Human	0.63887768
65	DNAJC2_21179169_ChIP-ChIP_NT2_Human	0.63688941
66	LXR_22292898_ChIP-Seq_THP-1_Human	0.62400149
67	RAD21_21589869_ChIP-Seq_MESCs_Mouse	0.60985403
68	MYC_19829295_ChIP-Seq_ESCs_Human	0.60635959
69	SALL4_18804426_ChIP-ChIP_XEN_Mouse	0.60631530
70	FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human	0.60342206
71	SPI1_20517297_ChIP-Seq_HL60_Human	0.60122273
72	GATA2_20887958_ChIP-Seq_HPC-7_Mouse	0.59485372
73	ETV2_25802403_ChIP-Seq_MESCs_Mouse	0.59441893
74	SA1_27219007_Chip-Seq_Bcells_Human	0.59276376
75	SRY_22984422_ChIP-ChIP_TESTIS_Rat	0.58877585
76	GATA6_21074721_ChIP-Seq_CACO-2_Mouse	0.57750933
77	TP53_18474530_ChIP-ChIP_U2OS_Human	0.56736999
78	CTCF_20526341_ChIP-Seq_ESCs_Human	0.56585204
79	CEBPB_22108803_ChIP-Seq_LS180_Human	0.56312846
80	NFYA_21822215_ChIP-Seq_K562_Human	0.56289774
81	NRF2_20460467_ChIP-Seq_MEFs_Mouse	0.55488418
82	NFE2L2_20460467_ChIP-Seq_MEFs_Mouse	0.55488418
83	CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse	0.53670093
84	GATA6_21074721_ChIP-Seq_CACO-2_Human	0.52585862
85	NR4A2_19515692_ChIP-ChIP_MN9D_Mouse	0.52515485
86	PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse	0.52486032
87	CDX2_20551321_ChIP-Seq_CACO-2_Human	0.51899195
88	EBNA1_20929547_Chip-Seq_RAJI-cells_Human	0.51724101
89	POU5F1_16518401_ChIP-PET_MESCs_Mouse	0.51684113
90	ESET_19884257_ChIP-Seq_ESCs_Mouse	0.51236467
91	AR_20517297_ChIP-Seq_VCAP_Human	0.50480321
92	FOXA1_26743006_Chip-Seq_LNCaP-abl_Human	0.49956252
93	FOXA1_25552417_ChIP-Seq_VCAP_Human	0.49462551
94	EGR1_19032775_ChIP-ChIP_M12_Human	0.48582424
95	MYC_19915707_ChIP-ChIP_AK7_Human	0.48104269
96	FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human	0.47662133
97	BCL6_27268052_Chip-Seq_Bcells_Human	0.45672165
98	SOX9_22984422_ChIP-ChIP_TESTIS_Rat	0.45615698
99	FOXO3_23340844_ChIP-Seq_DLD1_Human	0.45478687
100	PPARD_23208498_ChIP-Seq_MDA-MB-231_Human	0.45457487
101	CBX2_22325352_ChIP-Seq_293T-Rex_Human	0.45167168
102	PHF8_20622854_ChIP-Seq_HELA_Human	0.44844041
103	NFE2_27457419_Chip-Seq_LIVER_Mouse	0.44757105
104	P53_21459846_ChIP-Seq_SAOS-2_Human	0.44619617
105	SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse	0.44158291
106	PPARG_20887899_ChIP-Seq_3T3-L1_Mouse	0.44056646
107	IRF1_19129219_ChIP-ChIP_H3396_Human	0.43163637
108	E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse	0.43146431
109	PBX1_22567123_ChIP-ChIP_OVCAR3_Human	0.42396024
110	ERG_21242973_ChIP-ChIP_JURKAT_Human	0.41588477
111	STAT3_19079543_ChIP-ChIP_MESCs_Mouse	0.41562131
112	ESR1_21235772_ChIP-Seq_MCF-7_Human	0.41459272
113	GATA1_19941827_ChIP-Seq_MEL_Mouse	0.41398190
114	GATA6_25053715_ChIP-Seq_YYC3_Human	0.41388080
115	MYC_27129775_Chip-Seq_CORNEA_Mouse	0.40780244
116	GATA1_19941826_ChIP-Seq_K562_Human	0.40434596
117	TAF2_19829295_ChIP-Seq_ESCs_Human	0.39542696
118	STAT1_17558387_ChIP-Seq_HELA_Human	0.39463750
119	SPI1_26923725_Chip-Seq_HPCs_Mouse	0.39302491
120	CEBPB_26923725_Chip-Seq_MACROPHAGESS_Mouse	0.38576615
121	CBP_21632823_ChIP-Seq_H3396_Human	0.38489540
122	GATA2_19941826_ChIP-Seq_K562_Human	0.38148878
123	POU5F1_18700969_ChIP-ChIP_MESCs_Mouse	0.37221519
124	FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human	0.37172173
125	PPAR_26484153_Chip-Seq_NCI-H1993_Human	0.36485845
126	GATA3_20176728_ChIP-ChIP_TSCs_Mouse	0.36166719
127	BCOR_27268052_Chip-Seq_Bcells_Human	0.35775353
128	CSB_26484114_Chip-Seq_FIBROBLAST_Human	0.34842857
129	P63_20808887_ChIP-Seq_KERATINOCYTES_Human	0.34826004
130	SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse	0.34545332
131	ESR1_20079471_ChIP-ChIP_T-47D_Human	0.34528768
132	GATA3_24758297_ChIP-Seq_MCF-7_Human	0.33995445
133	SOX3_22085726_ChIP-Seq_MUSCLE_Mouse	0.33992796
134	ERG_20517297_ChIP-Seq_VCAP_Human	0.33640490

Predicted mouse phenotypes (MGI)

Rank	Gene Set	Z-score
1	MP0002139_abnormal_hepatobiliary_system	8.31496211
2	MP0005360_urolithiasis	7.46757649
3	MP0005085_abnormal_gallbladder_physiolo	6.47146170
4	MP0005365_abnormal_bile_salt	6.18606112
5	MP0008875_abnormal_xenobiotic_pharmacok	5.19763123
6	MP0003806_abnormal_nucleotide_metabolis	4.17785390
7	MP0003252_abnormal_bile_duct	3.93370918
8	MP0010329_abnormal_lipoprotein_level	3.61289789
9	MP0009840_abnormal_foam_cell	3.38196306
10	MP0005083_abnormal_biliary_tract	3.04871803
11	MP0003195_calcinosis	2.79510854
12	MP0005332_abnormal_amino_acid	2.76051332
13	MP0001666_abnormal_nutrient_absorption	2.56454684
14	MP0003191_abnormal_cellular_cholesterol	2.40544065
15	MP0000609_abnormal_liver_physiology	2.19987940
16	MP0004019_abnormal_vitamin_homeostasis	2.11241293
17	MP0002118_abnormal_lipid_homeostasis	2.11061566
18	MP0002138_abnormal_hepatobiliary_system	1.95642911
19	MP0003868_abnormal_feces_composition	1.93496692
20	MP0005319_abnormal_enzyme/_coenzyme	1.86087691
21	MP0003011_delayed_dark_adaptation	1.66621913
22	MP0001764_abnormal_homeostasis	1.64330018
23	MP0005584_abnormal_enzyme/coenzyme_acti	1.55686858
24	MP0005451_abnormal_body_composition	1.53653834
25	MP0009697_abnormal_copulation	1.52077879
26	MP0003656_abnormal_erythrocyte_physiolo	1.28298660
27	MP0003705_abnormal_hypodermis_morpholog	1.27075903
28	MP0003186_abnormal_redox_activity	1.26114605
29	MP0002254_reproductive_system_inflammat	1.22970244
30	MP0009643_abnormal_urine_homeostasis	1.20579828
31	MP0000598_abnormal_liver_morphology	1.20432728
32	MP0005647_abnormal_sex_gland	1.11374380
33	MP0000604_amyloidosis	1.06617141
34	MP0002282_abnormal_trachea_morphology	1.05546223
35	MP0009764_decreased_sensitivity_to	1.04410455
36	MP0009763_increased_sensitivity_to	1.02154192
37	MP0010368_abnormal_lymphatic_system	0.97092217
38	MP0005670_abnormal_white_adipose	0.94289679
39	MP0005636_abnormal_mineral_homeostasis	0.89012602
40	MP0008469_abnormal_protein_level	0.87818076
41	MP0002249_abnormal_larynx_morphology	0.86710062
42	MP0009642_abnormal_blood_homeostasis	0.86188196
43	MP0006036_abnormal_mitochondrial_physio	0.84348963
44	MP0005376_homeostasis/metabolism_phenot	0.82420927
45	MP0001915_intracranial_hemorrhage	0.81453553
46	MP0009765_abnormal_xenobiotic_induced	0.78298957
47	MP0005408_hypopigmentation	0.78133933
48	MP0002078_abnormal_glucose_homeostasis	0.77622586
49	MP0003879_abnormal_hair_cell	0.75404455
50	MP0002876_abnormal_thyroid_physiology	0.73751097
51	MP0002971_abnormal_brown_adipose	0.72061143
52	MP0005266_abnormal_metabolism	0.70888400
53	MP0005084_abnormal_gallbladder_morpholo	0.68171649
54	MP0005334_abnormal_fat_pad	0.67795241
55	MP0006035_abnormal_mitochondrial_morpho	0.66820552
56	MP0003690_abnormal_glial_cell	0.65163652
57	MP0004130_abnormal_muscle_cell	0.65001043
58	MP0005220_abnormal_exocrine_pancreas	0.64668769
59	MP0009785_altered_susceptibility_to	0.64016570
60	MP0005535_abnormal_body_temperature	0.63046350
61	MP0009053_abnormal_anal_canal	0.62919236
62	MP0005023_abnormal_wound_healing	0.62249255
63	MP0005187_abnormal_penis_morphology	0.61631801
64	MP0000639_abnormal_adrenal_gland	0.61611146
65	MP0001661_extended_life_span	0.61403773
66	MP0003329_amyloid_beta_deposits	0.58307972
67	MP0001756_abnormal_urination	0.57919939
68	MP0005448_abnormal_energy_balance	0.54669971
69	MP0005464_abnormal_platelet_physiology	0.51131483
70	MP0005395_other_phenotype	0.46604816
71	MP0008873_increased_physiological_sensi	0.46571289
72	MP0002822_catalepsy	0.45888257
73	MP0008874_decreased_physiological_sensi	0.45692235
74	MP0000566_synostosis	0.45451723
75	MP0003638_abnormal_response/metabolism_	0.45427932
76	MP0005248_abnormal_Harderian_gland	0.44678381
77	MP0000467_abnormal_esophagus_morphology	0.44640173
78	MP0002136_abnormal_kidney_physiology	0.43670204
79	MP0006292_abnormal_olfactory_placode	0.43512551
80	MP0002928_abnormal_bile_duct	0.43092890
81	MP0003718_maternal_effect	0.42956604
82	MP0003436_decreased_susceptibility_to	0.42831696
83	MP0005666_abnormal_adipose_tissue	0.41849412
84	MP0005397_hematopoietic_system_phenotyp	0.41230210
85	MP0001545_abnormal_hematopoietic_system	0.41230210
86	MP0008872_abnormal_physiological_respon	0.40027378
87	MP0003075_altered_response_to	0.39906104
88	MP0004782_abnormal_surfactant_physiolog	0.39723176
89	MP0003953_abnormal_hormone_level	0.38855001
90	MP0006082_CNS_inflammation	0.38074592
91	MP0004381_abnormal_hair_follicle	0.37549990
92	MP0009115_abnormal_fat_cell	0.36455221
93	MP0002970_abnormal_white_adipose	0.36331950
94	MP0002837_dystrophic_cardiac_calcinosis	0.36294191
95	MP0003724_increased_susceptibility_to	0.36185281
96	MP0009672_abnormal_birth_weight	0.35889989
97	MP0004883_abnormal_blood_vessel	0.35871887
98	MP0001243_abnormal_dermal_layer	0.34672220
99	MP0004264_abnormal_extraembryonic_tissu	0.34416248
100	MP0005166_decreased_susceptibility_to	0.34368619
101	MP0002332_abnormal_exercise_endurance	0.34239893
102	MP0001986_abnormal_taste_sensitivity	0.33969771
103	MP0000249_abnormal_blood_vessel	0.33264825
104	MP0005058_abnormal_lysosome_morphology	0.31477154
105	MP0001853_heart_inflammation	0.30778551
106	MP0000579_abnormal_nail_morphology	0.30747024
107	MP0002796_impaired_skin_barrier	0.30674334
108	MP0000230_abnormal_systemic_arterial	0.29319027
109	MP0002168_other_aberrant_phenotype	0.28234489
110	MP0009384_cardiac_valve_regurgitation	0.27568337
111	MP0002132_abnormal_respiratory_system	0.27362744
112	MP0001845_abnormal_inflammatory_respons	0.26988786
113	MP0001881_abnormal_mammary_gland	0.26804826
114	MP0005164_abnormal_response_to	0.25752399
115	MP0001851_eye_inflammation	0.25557754
116	MP0002090_abnormal_vision	0.22375906
117	MP0002128_abnormal_blood_circulation	0.22004451
118	MP0000678_abnormal_parathyroid_gland	0.19869394
119	MP0003878_abnormal_ear_physiology	0.19506288
120	MP0005377_hearing/vestibular/ear_phenot	0.19506288

Predicted human phenotypes

Rank	Gene Set	Z-score
1	Abnormality of aromatic amino acid family metabolism (HP:0004338)	7.46966171
2	Deep venous thrombosis (HP:0002625)	7.44203445
3	Intrahepatic cholestasis (HP:0001406)	7.20504006
4	Abnormality of monocarboxylic acid metabolism (HP:0010996)	6.75944458
5	Prolonged partial thromboplastin time (HP:0003645)	6.54031429
6	Hypobetalipoproteinemia (HP:0003563)	6.45379301
7	Xanthomatosis (HP:0000991)	6.42099837
8	Hyperlipoproteinemia (HP:0010980)	5.73839062
9	Complement deficiency (HP:0004431)	5.24823933
10	Hypolipoproteinemia (HP:0010981)	4.87746299
11	Joint hemorrhage (HP:0005261)	4.82226173
12	Hyperammonemia (HP:0001987)	4.64670523
13	Epidermoid cyst (HP:0200040)	4.52791330
14	Abnormality of the common coagulation pathway (HP:0010990)	4.47770345
15	Abnormality of the level of lipoprotein cholesterol (HP:0010979)	4.45925940
16	Abnormality of methionine metabolism (HP:0010901)	4.41568146
17	Hypoalphalipoproteinemia (HP:0003233)	4.37427464
18	Hyperglycinemia (HP:0002154)	4.31308932
19	Abnormality of sulfur amino acid metabolism (HP:0004339)	4.29159569
20	Ketosis (HP:0001946)	4.28450342
21	Abnormality of aspartate family amino acid metabolism (HP:0010899)	4.20150574
22	Abnormality of glutamine family amino acid metabolism (HP:0010902)	4.08244579
23	Nephritis (HP:0000123)	4.05530329
24	Fat malabsorption (HP:0002630)	4.00460043
25	Abnormality of pyrimidine metabolism (HP:0004353)	3.91835349
26	Hyperglycinuria (HP:0003108)	3.89011651
27	Abnormality of the intrinsic pathway (HP:0010989)	3.88800174
28	Abnormality of glycine metabolism (HP:0010895)	3.85844023
29	Abnormality of serine family amino acid metabolism (HP:0010894)	3.85844023
30	Abnormality of complement system (HP:0005339)	3.84757507
31	Hypoglycemic coma (HP:0001325)	3.78775724
32	Hypercholesterolemia (HP:0003124)	3.65892798
33	Conjugated hyperbilirubinemia (HP:0002908)	3.57735318
34	Abnormality of long-chain fatty-acid metabolism (HP:0010964)	3.37239539
35	Hyperbilirubinemia (HP:0002904)	3.35711956
36	Abnormality of fatty-acid metabolism (HP:0004359)	3.32018425
37	Hypochromic microcytic anemia (HP:0004840)	3.30768649
38	Spontaneous abortion (HP:0005268)	3.11461593
39	Abnormality of nucleobase metabolism (HP:0010932)	3.10992097
40	Delayed CNS myelination (HP:0002188)	3.05219959
41	Hepatocellular carcinoma (HP:0001402)	3.03105438
42	Abnormality of serum amino acid levels (HP:0003112)	3.02600375
43	Steatorrhea (HP:0002570)	3.01213313
44	Ketoacidosis (HP:0001993)	2.98028894
45	Myocardial infarction (HP:0001658)	2.91928363
46	Skin nodule (HP:0200036)	2.91040760
47	Metabolic acidosis (HP:0001942)	2.79747550
48	Neonatal hypoglycemia (HP:0001998)	2.77465261
49	Abnormality of purine metabolism (HP:0004352)	2.70570471
50	Systemic lupus erythematosus (HP:0002725)	2.65383951
51	Gout (HP:0001997)	2.63629159
52	Purpura (HP:0000979)	2.60792193
53	Lethargy (HP:0001254)	2.59342024
54	Abnormality of dicarboxylic acid metabolism (HP:0010995)	2.57678604
55	Dicarboxylic aciduria (HP:0003215)	2.57678604
56	Vascular calcification (HP:0004934)	2.52822270
57	Abnormal gallbladder morphology (HP:0012437)	2.49107112
58	Spastic diplegia (HP:0001264)	2.48443501
59	Fair hair (HP:0002286)	2.47044395
60	Cholecystitis (HP:0001082)	2.45165881
61	Abnormal gallbladder physiology (HP:0012438)	2.45165881
62	Acanthocytosis (HP:0001927)	2.45023979
63	Cholelithiasis (HP:0001081)	2.44991655
64	Amyloidosis (HP:0011034)	2.44810930
65	Irritability (HP:0000737)	2.40261537
66	Malnutrition (HP:0004395)	2.39927013
67	Glomerulonephritis (HP:0000099)	2.39364839
68	Hypoglycemic seizures (HP:0002173)	2.39158485
69	Cerebral edema (HP:0002181)	2.37141753
70	Mitral stenosis (HP:0001718)	2.36409500
71	Pulmonary embolism (HP:0002204)	2.35891064
72	Neonatal onset (HP:0003623)	2.30910467
73	Gingival bleeding (HP:0000225)	2.30045769
74	Osteomalacia (HP:0002749)	2.26199882
75	Recurrent gram-negative bacterial infections (HP:0005420)	2.24902588
76	Cardiovascular calcification (HP:0011915)	2.23483592
77	Enlarged kidneys (HP:0000105)	2.18661009
78	Menorrhagia (HP:0000132)	2.17055452
79	Brushfield spots (HP:0001088)	2.16174356
80	Hyperinsulinemic hypoglycemia (HP:0000825)	2.15462872
81	Esophageal varix (HP:0002040)	2.15267820
82	Pancreatitis (HP:0001733)	2.13566873
83	Thrombophlebitis (HP:0004418)	2.09727079
84	Late onset (HP:0003584)	2.09168402
85	Vomiting (HP:0002013)	2.08670613
86	Sensorimotor neuropathy (HP:0007141)	2.06913034
87	Abnormal cartilage morphology (HP:0002763)	2.03653953
88	Joint swelling (HP:0001386)	2.03258409
89	Abnormality of the gallbladder (HP:0005264)	2.01351674
90	Hemorrhage of the eye (HP:0011885)	1.99690209
91	Poikilocytosis (HP:0004447)	1.98169328
92	Opisthotonus (HP:0002179)	1.97448070
93	Generalized aminoaciduria (HP:0002909)	1.96965753
94	Abnormality of iron homeostasis (HP:0011031)	1.95790705
95	Rickets (HP:0002748)	1.94421355
96	Elevated alkaline phosphatase (HP:0003155)	1.94262887
97	Abnormality of transition element cation homeostasis (HP:0011030)	1.90898857
98	Increased serum ferritin (HP:0003281)	1.88478356
99	Status epilepticus (HP:0002133)	1.88160470
100	Epistaxis (HP:0000421)	1.87589064
101	Gangrene (HP:0100758)	1.82584250
102	Hyperphosphaturia (HP:0003109)	1.82448729
103	Abnormal enzyme/coenzyme activity (HP:0012379)	1.81242568
104	Hypophosphatemic rickets (HP:0004912)	1.80987873
105	Elevated hepatic transaminases (HP:0002910)	1.80726713
106	Abnormality of alkaline phosphatase activity (HP:0004379)	1.80180115
107	Renal cortical cysts (HP:0000803)	1.77877977
108	Hydroxyprolinuria (HP:0003080)	1.76914577
109	Abnormality of proline metabolism (HP:0010907)	1.76914577
110	Alkalosis (HP:0001948)	1.75486136
111	Hyperuricemia (HP:0002149)	1.75293341
112	Increased purine levels (HP:0004368)	1.75293341
113	Reticulocytosis (HP:0001923)	1.74672347
114	Abnormality of the Achilles tendon (HP:0005109)	1.74210750
115	Reduced antithrombin III activity (HP:0001976)	1.72649501
116	Atrioventricular block (HP:0001678)	1.72399901
117	Generalized hypopigmentation of hair (HP:0011358)	1.70717702
118	Bifid scrotum (HP:0000048)	1.67982328
119	Abnormal delivery (HP:0001787)	1.64178737
120	Cerebral palsy (HP:0100021)	1.62740600
121	Arthropathy (HP:0003040)	1.62191115
122	Abnormality of urine glucose concentration (HP:0011016)	1.56058842
123	Glycosuria (HP:0003076)	1.56058842
124	Increased mean platelet volume (HP:0011877)	1.55113498
125	Abnormality of vitamin metabolism (HP:0100508)	1.54291786
126	Increased serum pyruvate (HP:0003542)	1.53719506
127	Blue irides (HP:0000635)	1.53080564
128	Abnormal urine phosphate concentration (HP:0012599)	1.49547037
129	Abnormal biliary tract physiology (HP:0012439)	1.49153994
130	Bile duct proliferation (HP:0001408)	1.49153994
131	Abnormal platelet function (HP:0011869)	1.45933565

Predicted kinase interactions (KEA)

Rank	Gene Set	Z-score
1	BCKDK	7.06020348
2	ERN1	5.13759847
3	FGFR4	4.41226504
4	SIK1	4.36208443
5	TAOK3	2.89997692
6	INSRR	2.79174302
7	ERBB4	2.78927909
8	MAP2K4	2.50299439
9	PKN2	2.24626040
10	NTRK3	2.18393644
11	PIK3CA	1.97799527
12	MST1R	1.93990412
13	FLT3	1.92570559
14	MAPK11	1.82951147
15	TRIB3	1.80216615
16	GRK6	1.77836893
17	TYK2	1.65563145
18	LATS1	1.57309300
19	PIK3CG	1.55462080
20	ABL2	1.46506856
21	PTK6	1.37889869
22	DAPK2	1.35755017
23	MAP3K7	1.26975740
24	TNK2	1.25903085
25	MAP3K10	1.23689606
26	KDR	1.22586463
27	NEK9	1.21484842
28	FGFR2	1.21240822
29	PRPF4B	1.20653892
30	JAK2	1.19632903
31	PINK1	1.11265997
32	PRKAA2	1.07300516
33	BLK	1.07085965
34	ERBB2	1.06556881
35	FRK	1.05691015
36	MAP2K3	1.05162573
37	NLK	1.04907486
38	MAPK4	1.04509040
39	TBK1	0.98109095
40	CSF1R	0.96726704
41	TGFBR2	0.95831606
42	GRK1	0.94910918
43	MAPK7	0.94031051
44	MAPK12	0.91829676
45	JAK1	0.91596028
46	FER	0.90020796
47	PRKCZ	0.86797469
48	CSK	0.84967708
49	MAP3K3	0.83570110
50	MAP3K14	0.82897076
51	PRKG1	0.82319158
52	MAP2K6	0.81319759
53	EPHB1	0.81234764
54	MET	0.80990799
55	STK38L	0.80175914
56	MAPK15	0.77674927
57	CDK6	0.77431568
58	PRKACA	0.77397582
59	PRKACG	0.77289012
60	MAP3K11	0.73665842
61	PDK2	0.73420098
62	DYRK1B	0.72235024
63	MAP3K2	0.72050977
64	CAMKK2	0.71749812
65	EPHA3	0.71701147
66	ZAP70	0.70124533
67	FGFR3	0.69468469
68	GSK3A	0.68654229
69	TIE1	0.67331922
70	CAMK2G	0.64410072
71	PRKAA1	0.63366197
72	RIPK1	0.60876506
73	PTK2	0.60051416
74	CAMK1D	0.56724285
75	SGK3	0.54701838
76	CAMK4	0.54594339
77	IRAK3	0.53569910
78	CSNK1E	0.52785206
79	TAOK2	0.50496295
80	SGK494	0.49750065
81	RPS6KA3	0.49543163
82	GRK5	0.48799722
83	MAP4K1	0.48414965
84	CDK4	0.47952990
85	IGF1R	0.47617138
86	CAMKK1	0.47260959
87	PRKCQ	0.47112137
88	CSNK1D	0.46972823
89	PDPK1	0.46411104
90	PRKCB	0.45304878
91	IKBKE	0.44845687
92	MAP3K5	0.44737360
93	MTOR	0.42220229
94	SRC	0.41901550
95	SGK1	0.40951542
96	PRKCG	0.40947006
97	EPHA4	0.39896803
98	CDK12	0.38955159
99	CSNK1G1	0.38712909
100	ICK	0.38671365
101	LATS2	0.37654999
102	SMG1	0.37599698
103	EPHA2	0.37209055
104	PDGFRA	0.37110960
105	CSNK2A1	0.36641751
106	WNK4	0.35753611
107	MAP2K1	0.34890719
108	RET	0.34888196
109	EGFR	0.33866020
110	PKN1	0.33795731
111	MAP3K6	0.32965651
112	SGK2	0.32416852
113	PDK1	0.32026192
114	ADRBK2	0.29471657
115	CSNK2A2	0.29032410
116	MAP3K13	0.28769162
117	MYLK	0.28058041
118	KSR2	0.27571290
119	AKT3	0.24748596
120	BMX	0.23626012
121	PRKCA	0.23067257
122	MAP3K1	0.20540036
123	ABL1	0.20472137
124	MAP2K2	0.19629106
125	ITK	0.19380692
126	MAPK3	0.18904409
127	PRKACB	0.18562961
128	IRAK2	0.18332585
129	CSNK1G2	0.18152693
130	SGK223	0.18105818

Predicted pathways (KEGG)

Rank	Gene Set	Z-score
1	Primary bile acid biosynthesis_Homo sapiens_hsa00120	4.51944241
2	Nitrogen metabolism_Homo sapiens_hsa00910	3.54721536
3	Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400	3.43635809
4	Ascorbate and aldarate metabolism_Homo sapiens_hsa00053	3.34416362
5	Arginine biosynthesis_Homo sapiens_hsa00220	3.09514871
6	Complement and coagulation cascades_Homo sapiens_hsa04610	2.79050287
7	Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040	2.74707182
8	Tryptophan metabolism_Homo sapiens_hsa00380	2.68454579
9	Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630	2.60455213
10	Glycine, serine and threonine metabolism_Homo sapiens_hsa00260	2.55934809
11	Fatty acid degradation_Homo sapiens_hsa00071	2.49077786
12	Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280	2.38009227
13	Pentose and glucuronate interconversions_Homo sapiens_hsa00040	2.29869650
14	Butanoate metabolism_Homo sapiens_hsa00650	2.12437077
15	Drug metabolism - cytochrome P450_Homo sapiens_hsa00982	2.11600667
16	Peroxisome_Homo sapiens_hsa04146	2.08318031
17	Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980	1.97180852
18	Chemical carcinogenesis_Homo sapiens_hsa05204	1.97110227
19	PPAR signaling pathway_Homo sapiens_hsa03320	1.91431968
20	Steroid hormone biosynthesis_Homo sapiens_hsa00140	1.89968110
21	Histidine metabolism_Homo sapiens_hsa00340	1.88692540
22	Propanoate metabolism_Homo sapiens_hsa00640	1.87451715
23	Fatty acid metabolism_Homo sapiens_hsa01212	1.79995298
24	Drug metabolism - other enzymes_Homo sapiens_hsa00983	1.76864669
25	Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250	1.76318524
26	Staphylococcus aureus infection_Homo sapiens_hsa05150	1.74152081
27	beta-Alanine metabolism_Homo sapiens_hsa00410	1.69604057
28	Retinol metabolism_Homo sapiens_hsa00830	1.68845235
29	Caffeine metabolism_Homo sapiens_hsa00232	1.67234565
30	Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770	1.65755399
31	Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072	1.59701253
32	Selenocompound metabolism_Homo sapiens_hsa00450	1.58733657
33	Phenylalanine metabolism_Homo sapiens_hsa00360	1.55856997
34	2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210	1.52272572
35	Bile secretion_Homo sapiens_hsa04976	1.49674242
36	Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130	1.49581403
37	Tyrosine metabolism_Homo sapiens_hsa00350	1.42706076
38	Pyruvate metabolism_Homo sapiens_hsa00620	1.35284801
39	Cysteine and methionine metabolism_Homo sapiens_hsa00270	1.35266847
40	Fatty acid elongation_Homo sapiens_hsa00062	1.32737956
41	Starch and sucrose metabolism_Homo sapiens_hsa00500	1.28720975
42	Sulfur metabolism_Homo sapiens_hsa00920	1.27718443
43	Folate biosynthesis_Homo sapiens_hsa00790	1.24417101
44	Biosynthesis of amino acids_Homo sapiens_hsa01230	1.22811577
45	ABC transporters_Homo sapiens_hsa02010	1.19591409
46	Fat digestion and absorption_Homo sapiens_hsa04975	1.16902571
47	Steroid biosynthesis_Homo sapiens_hsa00100	1.14078559
48	Carbon metabolism_Homo sapiens_hsa01200	1.13086261
49	Vitamin B6 metabolism_Homo sapiens_hsa00750	1.06734110
50	Taurine and hypotaurine metabolism_Homo sapiens_hsa00430	1.00518140
51	Maturity onset diabetes of the young_Homo sapiens_hsa04950	0.98853098
52	Sulfur relay system_Homo sapiens_hsa04122	0.97896769
53	Cyanoamino acid metabolism_Homo sapiens_hsa00460	0.96449470
54	Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860	0.96301355
55	Arginine and proline metabolism_Homo sapiens_hsa00330	0.96093872
56	Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760	0.87319737
57	Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964	0.84117328
58	Vitamin digestion and absorption_Homo sapiens_hsa04977	0.83989892
59	Lysine degradation_Homo sapiens_hsa00310	0.81392817
60	One carbon pool by folate_Homo sapiens_hsa00670	0.76242516
61	Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010	0.73168917
62	Glycerolipid metabolism_Homo sapiens_hsa00561	0.68197610
63	Glutathione metabolism_Homo sapiens_hsa00480	0.63512906
64	Pentose phosphate pathway_Homo sapiens_hsa00030	0.60384758
65	Fatty acid biosynthesis_Homo sapiens_hsa00061	0.49542063
66	Citrate cycle (TCA cycle)_Homo sapiens_hsa00020	0.46498799
67	Metabolic pathways_Homo sapiens_hsa01100	0.46274997
68	Pertussis_Homo sapiens_hsa05133	0.46090525
69	Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524	0.36974786
70	Fructose and mannose metabolism_Homo sapiens_hsa00051	0.33803317
71	Prion diseases_Homo sapiens_hsa05020	0.33730261
72	Galactose metabolism_Homo sapiens_hsa00052	0.32647382
73	alpha-Linolenic acid metabolism_Homo sapiens_hsa00592	0.31568617
74	Linoleic acid metabolism_Homo sapiens_hsa00591	0.26861528
75	Insulin resistance_Homo sapiens_hsa04931	0.24694824
76	Adipocytokine signaling pathway_Homo sapiens_hsa04920	0.24248611
77	Glycerophospholipid metabolism_Homo sapiens_hsa00564	0.18473455
78	Terpenoid backbone biosynthesis_Homo sapiens_hsa00900	0.15721789
79	Amoebiasis_Homo sapiens_hsa05146	0.11854013
80	Glucagon signaling pathway_Homo sapiens_hsa04922	0.10568168
81	Mineral absorption_Homo sapiens_hsa04978	0.08696593
82	AMPK signaling pathway_Homo sapiens_hsa04152	0.04579154
83	Other glycan degradation_Homo sapiens_hsa00511	0.04257469
84	FoxO signaling pathway_Homo sapiens_hsa04068	-0.2787956
85	N-Glycan biosynthesis_Homo sapiens_hsa00510	-0.2745330
86	Type II diabetes mellitus_Homo sapiens_hsa04930	-0.2675784
87	Bladder cancer_Homo sapiens_hsa05219	-0.2414064
88	RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622	-0.2403887
89	Ether lipid metabolism_Homo sapiens_hsa00565	-0.2351388
90	Longevity regulating pathway - mammal_Homo sapiens_hsa04211	-0.2328242
91	Sphingolipid metabolism_Homo sapiens_hsa00600	-0.2326528
92	Carbohydrate digestion and absorption_Homo sapiens_hsa04973	-0.2287803
93	Thyroid hormone synthesis_Homo sapiens_hsa04918	-0.2158580
94	Circadian rhythm_Homo sapiens_hsa04710	-0.2084553
95	Vascular smooth muscle contraction_Homo sapiens_hsa04270	-0.2054389
96	Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141	-0.1937357
97	Renin-angiotensin system_Homo sapiens_hsa04614	-0.1913349
98	Hepatitis C_Homo sapiens_hsa05160	-0.1747076
99	Systemic lupus erythematosus_Homo sapiens_hsa05322	-0.1674791
100	Central carbon metabolism in cancer_Homo sapiens_hsa05230	-0.1404965
101	Glycosaminoglycan degradation_Homo sapiens_hsa00531	-0.1335819
102	Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604	-0.1283402
103	Regulation of autophagy_Homo sapiens_hsa04140	-0.1264403
104	African trypanosomiasis_Homo sapiens_hsa05143	-0.1203402
105	Insulin signaling pathway_Homo sapiens_hsa04910	-0.1036244
106	Arachidonic acid metabolism_Homo sapiens_hsa00590	-0.1012029
107	Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534	-0.0681437
108	Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932	-0.0541244
109	Ovarian steroidogenesis_Homo sapiens_hsa04913	-0.0522980
110	Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520	-0.0400298
111	Serotonergic synapse_Homo sapiens_hsa04726	-0.0396356

SLC25A47

Functional Annotation Prediction

Predicted biological processes (GO)

Predicted upstream transcription factors (ChEA)

Predicted mouse phenotypes (MGI)

Predicted human phenotypes

Predicted kinase interactions (KEA)

Predicted pathways (KEGG)

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