SLC25A5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Suppressed expression of this gene has been shown to induce apoptosis and inhibit tumor growth. The human genome contains several non-transcribed pseudogenes of this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nucleobase biosynthetic process (GO:0046112)4.93618660
2purine nucleobase biosynthetic process (GO:0009113)4.81229769
3DNA strand elongation involved in DNA replication (GO:0006271)4.76108169
4ribosomal small subunit assembly (GO:0000028)4.64799601
5telomere maintenance via semi-conservative replication (GO:0032201)4.58908966
6DNA strand elongation (GO:0022616)4.53255234
7establishment of integrated proviral latency (GO:0075713)4.34792297
8oxidative phosphorylation (GO:0006119)4.30349526
9telomere maintenance via recombination (GO:0000722)4.17515907
10formation of translation preinitiation complex (GO:0001731)4.11190936
11DNA replication initiation (GO:0006270)4.00074051
12DNA deamination (GO:0045006)3.99099572
13mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.97495879
14IMP biosynthetic process (GO:0006188)3.92509053
15mitotic recombination (GO:0006312)3.82936070
16DNA replication checkpoint (GO:0000076)3.82463597
17negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.72224437
18cullin deneddylation (GO:0010388)3.71300353
19proteasome assembly (GO:0043248)3.68584312
20CENP-A containing nucleosome assembly (GO:0034080)3.66603100
21mitotic sister chromatid segregation (GO:0000070)3.65109364
22ATP synthesis coupled proton transport (GO:0015986)3.64608061
23energy coupled proton transport, down electrochemical gradient (GO:0015985)3.64608061
24protein deneddylation (GO:0000338)3.59603268
25regulation of ligase activity (GO:0051340)3.57479612
26positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.55638195
27telomere maintenance via telomere lengthening (GO:0010833)3.55622353
28chromatin remodeling at centromere (GO:0031055)3.55033775
29regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.54151143
30establishment of protein localization to mitochondrial membrane (GO:0090151)3.53769902
31anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.49367523
32regulation of cellular amino acid metabolic process (GO:0006521)3.46785759
33DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.44451462
34nucleotide-excision repair, DNA gap filling (GO:0006297)3.41729360
35establishment of viral latency (GO:0019043)3.40959683
36antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.40948185
37deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.40696705
38signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.39533047
39intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.39533047
40IMP metabolic process (GO:0046040)3.39356458
41maturation of SSU-rRNA (GO:0030490)3.38226539
42signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.37446599
43signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.37446599
44signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.37446599
45chaperone-mediated protein transport (GO:0072321)3.36630066
46negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.36530214
47negative regulation of ligase activity (GO:0051352)3.36530214
48regulation of cellular amine metabolic process (GO:0033238)3.30686628
49signal transduction involved in DNA damage checkpoint (GO:0072422)3.28413150
50signal transduction involved in DNA integrity checkpoint (GO:0072401)3.28413150
51regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.27321229
52ribosome biogenesis (GO:0042254)3.26074938
53pseudouridine synthesis (GO:0001522)3.25892815
54respiratory electron transport chain (GO:0022904)3.24701977
55antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.24247792
56sister chromatid segregation (GO:0000819)3.23703078
57signal transduction involved in cell cycle checkpoint (GO:0072395)3.22964830
58nucleobase-containing small molecule interconversion (GO:0015949)3.20510601
59tricarboxylic acid cycle (GO:0006099)3.20344321
60L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.20286439
61viral mRNA export from host cell nucleus (GO:0046784)3.19215235
62G1/S transition of mitotic cell cycle (GO:0000082)3.18688596
63cell cycle G1/S phase transition (GO:0044843)3.18688596
64mitotic metaphase plate congression (GO:0007080)3.18317412
65rRNA modification (GO:0000154)3.18006038
66ribosomal large subunit biogenesis (GO:0042273)3.17089471
67DNA unwinding involved in DNA replication (GO:0006268)3.16787705
68electron transport chain (GO:0022900)3.15678272
69DNA ligation (GO:0006266)3.12046481
70negative regulation of protein ubiquitination (GO:0031397)3.10691789
71DNA replication-independent nucleosome organization (GO:0034724)3.08072727
72DNA replication-independent nucleosome assembly (GO:0006336)3.08072727
73mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.07232669
74protein targeting to mitochondrion (GO:0006626)3.06924585
75tRNA aminoacylation for protein translation (GO:0006418)3.06881387
76transcription-coupled nucleotide-excision repair (GO:0006283)3.06621671
77positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.06191988
78melanin biosynthetic process (GO:0042438)3.06189211
79amino acid activation (GO:0043038)3.04258171
80tRNA aminoacylation (GO:0043039)3.04258171
81protein localization to kinetochore (GO:0034501)3.04232621
82DNA catabolic process, exonucleolytic (GO:0000738)3.02461920
83folic acid-containing compound biosynthetic process (GO:0009396)3.02179827
84ribonucleoprotein complex biogenesis (GO:0022613)3.01999147
85respiratory chain complex IV assembly (GO:0008535)3.00583909
86pteridine-containing compound biosynthetic process (GO:0042559)3.00339443
87double-strand break repair via nonhomologous end joining (GO:0006303)2.99612202
88non-recombinational repair (GO:0000726)2.99612202
89rRNA methylation (GO:0031167)2.98688044
90negative regulation of protein modification by small protein conjugation or removal (GO:1903321)2.97355742
91positive regulation of ligase activity (GO:0051351)2.95122813
92protein maturation by protein folding (GO:0022417)2.92928361
93protein localization to chromosome, centromeric region (GO:0071459)2.92440890
94rRNA processing (GO:0006364)2.90283640
95deoxyribonucleotide biosynthetic process (GO:0009263)2.89841259
96mitotic nuclear envelope disassembly (GO:0007077)2.89613390
97spindle checkpoint (GO:0031577)2.89485491
98pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130)2.88682764
99spliceosomal snRNP assembly (GO:0000387)2.88483640
100kinetochore organization (GO:0051383)2.88105794
101signal transduction in response to DNA damage (GO:0042770)2.86625567
102regulation of translational termination (GO:0006449)2.86159943
103folic acid metabolic process (GO:0046655)2.85326267
104establishment of chromosome localization (GO:0051303)2.83108741
105telomere maintenance (GO:0000723)2.81329182
106telomere organization (GO:0032200)2.81259578
107termination of RNA polymerase III transcription (GO:0006386)2.80579943
108transcription elongation from RNA polymerase III promoter (GO:0006385)2.80579943
109antigen processing and presentation of peptide antigen via MHC class I (GO:0002474)2.79760110
110positive regulation of cell cycle arrest (GO:0071158)2.79758841
111rRNA metabolic process (GO:0016072)2.78342480
112metaphase plate congression (GO:0051310)2.77865826
113DNA damage response, signal transduction by p53 class mediator (GO:0030330)2.77683218
114regulation of mitochondrial translation (GO:0070129)2.77649586
115ribosome assembly (GO:0042255)2.77521788
116translation (GO:0006412)2.77075927
117regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.76968057
118cellular component biogenesis (GO:0044085)2.75807780
119pyrimidine nucleoside monophosphate metabolic process (GO:0009129)2.75476480
1207-methylguanosine mRNA capping (GO:0006370)2.73975356
121mitochondrial respiratory chain complex I assembly (GO:0032981)2.73145692
122NADH dehydrogenase complex assembly (GO:0010257)2.73145692
123mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.73145692
124histone exchange (GO:0043486)2.72021597
125aerobic respiration (GO:0009060)2.70394844
126attachment of spindle microtubules to kinetochore (GO:0008608)2.70258866
127regulation of ubiquitin-protein transferase activity (GO:0051438)2.70190490
128RNA capping (GO:0036260)2.69378582
1297-methylguanosine RNA capping (GO:0009452)2.69378582
130NADH metabolic process (GO:0006734)2.69272741
131deoxyribose phosphate biosynthetic process (GO:0046385)2.68851297

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.60171080
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.04448476
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.01213975
4* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.98647140
5EST1_17652178_ChIP-ChIP_JURKAT_Human3.34315193
6JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.30490663
7GABP_17652178_ChIP-ChIP_JURKAT_Human3.29094132
8E2F4_17652178_ChIP-ChIP_JURKAT_Human3.11822848
9CREB1_15753290_ChIP-ChIP_HEK293T_Human2.96936929
10NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.95763040
11ETS1_20019798_ChIP-Seq_JURKAT_Human2.89318957
12* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.88754506
13* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.70407869
14HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.68098858
15ELF1_17652178_ChIP-ChIP_JURKAT_Human2.65004956
16FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.61181153
17MYC_19079543_ChIP-ChIP_MESCs_Mouse2.55073623
18CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.38968092
19FOXM1_23109430_ChIP-Seq_U2OS_Human2.36418914
20VDR_23849224_ChIP-Seq_CD4+_Human2.35674716
21NELFA_20434984_ChIP-Seq_ESCs_Mouse2.31763569
22* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.19474158
23DCP1A_22483619_ChIP-Seq_HELA_Human2.11437837
24SRF_21415370_ChIP-Seq_HL-1_Mouse2.11314537
25HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.07871776
26FOXP3_21729870_ChIP-Seq_TREG_Human2.07646018
27XRN2_22483619_ChIP-Seq_HELA_Human2.06883334
28PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.04566617
29SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.03085477
30THAP11_20581084_ChIP-Seq_MESCs_Mouse1.94751110
31GABP_19822575_ChIP-Seq_HepG2_Human1.91176822
32AR_21909140_ChIP-Seq_LNCAP_Human1.88994957
33CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.86486390
34HOXB4_20404135_ChIP-ChIP_EML_Mouse1.85756084
35FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.82781295
36YY1_21170310_ChIP-Seq_MESCs_Mouse1.80748588
37PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.80353920
38ELK1_19687146_ChIP-ChIP_HELA_Human1.77338264
39E2F1_21310950_ChIP-Seq_MCF-7_Human1.73780659
40FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.66370258
41MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.66329017
42TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.64838217
43TTF2_22483619_ChIP-Seq_HELA_Human1.64415142
44POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.63184522
45E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.61909522
46MYCN_18555785_ChIP-Seq_MESCs_Mouse1.60232150
47* NANOG_18555785_ChIP-Seq_MESCs_Mouse1.59436964
48SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.57037063
49YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.55564080
50ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.51801165
51ERG_20887958_ChIP-Seq_HPC-7_Mouse1.47559363
52* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.46330389
53CIITA_25753668_ChIP-Seq_RAJI_Human1.39946861
54MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.37488225
55SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.35242080
56MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.31996740
57* PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.29580967
58KDM5A_27292631_Chip-Seq_BREAST_Human1.29360024
59TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.29092923
60HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.25890750
61PADI4_21655091_ChIP-ChIP_MCF-7_Human1.25711099
62CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.25061971
63IRF8_22096565_ChIP-ChIP_GC-B_Human1.24981579
64SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.23585869
65ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.22093682
66CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.18702334
67IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.16459625
68CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.16089618
69STAT3_1855785_ChIP-Seq_MESCs_Mouse1.15204480
70CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.15138928
71BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.11578300
72SPI1_23547873_ChIP-Seq_NB4_Human1.11405361
73POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.10931897
74KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.10694915
75SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.08890291
76TFEB_21752829_ChIP-Seq_HELA_Human1.08731440
77PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.07415500
78POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.06322183
79ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.05454958
80E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.03640967
81ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.00845409
82ESR1_15608294_ChIP-ChIP_MCF-7_Human1.00256141
83EGR1_19374776_ChIP-ChIP_THP-1_Human1.00198538
84GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.96562401
85MYC_22102868_ChIP-Seq_BL_Human0.95691898
86DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.95622738
87ZNF263_19887448_ChIP-Seq_K562_Human0.93693400
88ELK1_22589737_ChIP-Seq_MCF10A_Human0.93658986
89* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.91831996
90CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.89900561
91IRF8_21731497_ChIP-ChIP_J774_Mouse0.89213509
92MYC_18940864_ChIP-ChIP_HL60_Human0.88880034
93KLF4_18555785_ChIP-Seq_MESCs_Mouse0.88456547
94HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.85520704
95NOTCH1_21737748_ChIP-Seq_TLL_Human0.84254879
96RBPJ_22232070_ChIP-Seq_NCS_Mouse0.83566082
97ELF5_23300383_ChIP-Seq_T47D_Human0.83109177
98ESR1_17901129_ChIP-ChIP_LIVER_Mouse0.83048871
99DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.83037480
100NANOG_16153702_ChIP-ChIP_HESCs_Human0.81589341
101STAT4_19710469_ChIP-ChIP_TH1__Mouse0.79707046
102* NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.78809253
103HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.78198077
104MYB_21317192_ChIP-Seq_ERMYB_Mouse0.77396844
105TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.75856582
106TBX5_21415370_ChIP-Seq_HL-1_Mouse0.75405330
107TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse0.74934137
108SOX2_18555785_ChIP-Seq_MESCs_Mouse0.74189809
109GATA1_22383799_ChIP-Seq_G1ME_Mouse0.73563505
110NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.73347280
111CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.73293984
112SOX17_20123909_ChIP-Seq_XEN_Mouse0.73015401
113FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.71978680
114MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.71557209
115KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.69719944
116* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.69044413
117SOX2_18692474_ChIP-Seq_MEFs_Mouse0.68758298
118NANOG_18700969_ChIP-ChIP_MESCs_Mouse0.68340280

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching5.02613461
2MP0004957_abnormal_blastocyst_morpholog4.07375747
3MP0010094_abnormal_chromosome_stability3.98857790
4MP0003806_abnormal_nucleotide_metabolis3.70987741
5MP0003111_abnormal_nucleus_morphology3.41505587
6MP0003077_abnormal_cell_cycle3.25478695
7MP0008057_abnormal_DNA_replication3.17916246
8MP0008058_abnormal_DNA_repair2.99462339
9MP0002396_abnormal_hematopoietic_system2.86803532
10MP0003186_abnormal_redox_activity2.59591757
11MP0008007_abnormal_cellular_replicative2.59003335
12MP0010234_abnormal_vibrissa_follicle2.43966383
13MP0006036_abnormal_mitochondrial_physio2.31632603
14MP0008932_abnormal_embryonic_tissue2.16366358
15MP0000490_abnormal_crypts_of2.02723697
16MP0006054_spinal_hemorrhage1.96118316
17MP0005171_absent_coat_pigmentation1.95238956
18MP0002132_abnormal_respiratory_system1.88101485
19MP0000015_abnormal_ear_pigmentation1.84736851
20MP0002877_abnormal_melanocyte_morpholog1.78521316
21MP0003136_yellow_coat_color1.76408214
22MP0003123_paternal_imprinting1.75078389
23MP0001835_abnormal_antigen_presentation1.73649878
24MP0001730_embryonic_growth_arrest1.73433152
25MP0001764_abnormal_homeostasis1.73356415
26MP0009697_abnormal_copulation1.71323627
27MP0003786_premature_aging1.67231058
28MP0004147_increased_porphyrin_level1.66912127
29MP0009333_abnormal_splenocyte_physiolog1.66100049
30MP0003941_abnormal_skin_development1.65685006
31MP0002938_white_spotting1.65223053
32MP0010352_gastrointestinal_tract_polyps1.61340401
33MP0000350_abnormal_cell_proliferation1.52596469
34MP0003763_abnormal_thymus_physiology1.50266601
35MP0003718_maternal_effect1.47748568
36MP0002095_abnormal_skin_pigmentation1.47711773
37MP0008877_abnormal_DNA_methylation1.44312640
38MP0006035_abnormal_mitochondrial_morpho1.41156535
39MP0001853_heart_inflammation1.36517903
40MP0009785_altered_susceptibility_to1.33232741
41MP0002019_abnormal_tumor_incidence1.28051033
42MP0000313_abnormal_cell_death1.25406474
43MP0005397_hematopoietic_system_phenotyp1.24115641
44MP0001545_abnormal_hematopoietic_system1.24115641
45MP0004084_abnormal_cardiac_muscle1.23458113
46MP0002102_abnormal_ear_morphology1.21682605
47MP0005266_abnormal_metabolism1.21005842
48MP0005360_urolithiasis1.19370945
49MP0002796_impaired_skin_barrier1.17097623
50MP0002398_abnormal_bone_marrow1.15894733
51MP0005075_abnormal_melanosome_morpholog1.15835784
52MP0000371_diluted_coat_color1.14897813
53MP0004808_abnormal_hematopoietic_stem1.14797918
54MP0000689_abnormal_spleen_morphology1.13726939
55MP0005671_abnormal_response_to1.13545571
56MP0005174_abnormal_tail_pigmentation1.13054400
57MP0004782_abnormal_surfactant_physiolog1.12719033
58MP0003567_abnormal_fetal_cardiomyocyte1.12667167
59MP0002722_abnormal_immune_system1.12273443
60MP0003984_embryonic_growth_retardation1.12233747
61MP0001697_abnormal_embryo_size1.11969755
62MP0003221_abnormal_cardiomyocyte_apopto1.10861393
63MP0003866_abnormal_defecation1.10774539
64MP0002080_prenatal_lethality1.10247122
65MP0005501_abnormal_skin_physiology1.10127772
66MP0005408_hypopigmentation1.09790219
67MP0002148_abnormal_hypersensitivity_rea1.09767994
68MP0005380_embryogenesis_phenotype1.08833477
69MP0001672_abnormal_embryogenesis/_devel1.08833477
70MP0004381_abnormal_hair_follicle1.08107739
71MP0002088_abnormal_embryonic_growth/wei1.07473446
72MP0005332_abnormal_amino_acid1.06780281
73MP0001666_abnormal_nutrient_absorption1.06382163
74MP0002090_abnormal_vision1.06228318
75MP0001756_abnormal_urination1.04749143
76MP0002429_abnormal_blood_cell1.03122550
77MP0010155_abnormal_intestine_physiology1.01733175
78MP0010307_abnormal_tumor_latency1.00600400
79MP0004264_abnormal_extraembryonic_tissu0.97876788
80MP0009643_abnormal_urine_homeostasis0.97263036
81MP0003646_muscle_fatigue0.97122862
82MP0000358_abnormal_cell_content/0.97085010
83MP0000858_altered_metastatic_potential0.96478843
84MP0001324_abnormal_eye_pigmentation0.94281085
85MP0005025_abnormal_response_to0.94055526
86MP0005636_abnormal_mineral_homeostasis0.89549373
87MP0002085_abnormal_embryonic_tissue0.89422536
88MP0002420_abnormal_adaptive_immunity0.89396993
89MP0000716_abnormal_immune_system0.89082559
90MP0009672_abnormal_birth_weight0.88659772
91MP0001819_abnormal_immune_cell0.88529714
92MP0000372_irregular_coat_pigmentation0.85534135
93MP0002452_abnormal_antigen_presenting0.85512884
94MP0005319_abnormal_enzyme/_coenzyme0.85453372
95MP0002210_abnormal_sex_determination0.85166764
96MP0002086_abnormal_extraembryonic_tissu0.85110569
97MP0003878_abnormal_ear_physiology0.85054799
98MP0005377_hearing/vestibular/ear_phenot0.85054799
99MP0001929_abnormal_gametogenesis0.83504120
100MP0001727_abnormal_embryo_implantation0.83203457
101MP0001186_pigmentation_phenotype0.83051484
102MP0005376_homeostasis/metabolism_phenot0.82085089
103MP0000647_abnormal_sebaceous_gland0.81569667
104MP0001881_abnormal_mammary_gland0.81333407
105MP0000703_abnormal_thymus_morphology0.80293715
106MP0004019_abnormal_vitamin_homeostasis0.80149653
107MP0002084_abnormal_developmental_patter0.79700224
108MP0001800_abnormal_humoral_immune0.79446837
109MP0003943_abnormal_hepatobiliary_system0.77767720
110MP0001661_extended_life_span0.77606063
111MP0002419_abnormal_innate_immunity0.76851393
112MP0002405_respiratory_system_inflammati0.76747960
113MP0002139_abnormal_hepatobiliary_system0.76510552
114MP0009379_abnormal_foot_pigmentation0.76282350
115MP0002075_abnormal_coat/hair_pigmentati0.76099993
116MP0002006_tumorigenesis0.75877870
117MP0005395_other_phenotype0.74457130
118MP0001845_abnormal_inflammatory_respons0.74241142
119MP0001873_stomach_inflammation0.73557683
120MP0008469_abnormal_protein_level0.73242089
121MP0003656_abnormal_erythrocyte_physiolo0.73108569
122MP0000477_abnormal_intestine_morphology0.72963248
123MP0003950_abnormal_plasma_membrane0.72828942
124MP0000598_abnormal_liver_morphology0.72486489
125MP0000343_altered_response_to0.72430966
126MP0002723_abnormal_immune_serum0.71972486
127MP0001145_abnormal_male_reproductive0.70620194
128MP0008875_abnormal_xenobiotic_pharmacok0.70577074
129MP0004043_abnormal_pH_regulation0.70463070
130MP0005000_abnormal_immune_tolerance0.70243546
131MP0001293_anophthalmia0.67914998
132MP0005085_abnormal_gallbladder_physiolo0.67485275
133MP0003436_decreased_susceptibility_to0.67291492
134MP0003315_abnormal_perineum_morphology0.66910739
135MP0005330_cardiomyopathy0.66893747
136MP0000653_abnormal_sex_gland0.66826055
137MP0001119_abnormal_female_reproductive0.65131211
138MP0002160_abnormal_reproductive_system0.65011086
139MP0003890_abnormal_embryonic-extraembry0.62481003
140MP0005384_cellular_phenotype0.62228039
141MP0005257_abnormal_intraocular_pressure0.60924952
142MP0000537_abnormal_urethra_morphology0.56530586
143MP0005365_abnormal_bile_salt0.56082769
144MP0008995_early_reproductive_senescence0.55418402
145MP0008873_increased_physiological_sensi0.55011111
146MP0000516_abnormal_urinary_system0.54901141
147MP0005367_renal/urinary_system_phenotyp0.54901141
148MP0000627_abnormal_mammary_gland0.53872073

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)4.02472858
2Hepatic necrosis (HP:0002605)3.96589824
3Increased CSF lactate (HP:0002490)3.73267570
4Abnormal number of erythroid precursors (HP:0012131)3.72543817
5Acute necrotizing encephalopathy (HP:0006965)3.70968816
6Abnormal mitochondria in muscle tissue (HP:0008316)3.69005966
7Hepatocellular necrosis (HP:0001404)3.68700973
8Abnormality of glycolysis (HP:0004366)3.61464877
9Increased serum pyruvate (HP:0003542)3.61464877
10Mitochondrial inheritance (HP:0001427)3.56986690
11Abnormality of cells of the erythroid lineage (HP:0012130)3.43372068
12Oral leukoplakia (HP:0002745)3.42709345
13Increased serum lactate (HP:0002151)3.39615953
14Acute encephalopathy (HP:0006846)3.30017383
15Aplastic anemia (HP:0001915)3.24570478
16Degeneration of anterior horn cells (HP:0002398)3.12076908
17Abnormality of the anterior horn cell (HP:0006802)3.12076908
18Abnormal activity of mitochondrial respiratory chain (HP:0011922)3.08364174
19Decreased activity of mitochondrial respiratory chain (HP:0008972)3.08364174
20Nausea (HP:0002018)3.07227685
21Reticulocytopenia (HP:0001896)3.04553291
22Abnormality of methionine metabolism (HP:0010901)2.97867126
23Abnormal gallbladder physiology (HP:0012438)2.95469234
24Cholecystitis (HP:0001082)2.95469234
25Generalized aminoaciduria (HP:0002909)2.95052691
26Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.94146912
27Progressive macrocephaly (HP:0004481)2.88087782
28Lactic acidosis (HP:0003128)2.84808022
29Thrombocytosis (HP:0001894)2.83361071
30Type I transferrin isoform profile (HP:0003642)2.71521828
31Aplasia/Hypoplasia of the fovea (HP:0008060)2.71095205
32Hypoplasia of the fovea (HP:0007750)2.71095205
33Abnormality of aspartate family amino acid metabolism (HP:0010899)2.70963226
34Exercise intolerance (HP:0003546)2.69303843
35Patchy hypopigmentation of hair (HP:0011365)2.67747984
36Lipid accumulation in hepatocytes (HP:0006561)2.63133997
37Increased hepatocellular lipid droplets (HP:0006565)2.63018608
38Rough bone trabeculation (HP:0100670)2.62391769
39Agnosia (HP:0010524)2.60804012
40Multiple enchondromatosis (HP:0005701)2.58462659
41Proximal tubulopathy (HP:0000114)2.55718893
42Breast hypoplasia (HP:0003187)2.54039151
43Respiratory failure (HP:0002878)2.53541047
44Microvesicular hepatic steatosis (HP:0001414)2.48622114
45Cerebral edema (HP:0002181)2.46339442
46Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.43081376
47Aplasia/Hypoplasia of the uvula (HP:0010293)2.42759404
48Glycosuria (HP:0003076)2.41570745
49Abnormality of urine glucose concentration (HP:0011016)2.41570745
50Small intestinal stenosis (HP:0012848)2.39212600
51Duodenal stenosis (HP:0100867)2.39212600
52Aplasia/Hypoplasia of the macula (HP:0008059)2.36607878
53IgM deficiency (HP:0002850)2.34563607
54White forelock (HP:0002211)2.34128710
55Microretrognathia (HP:0000308)2.33790264
56Abnormality of the fovea (HP:0000493)2.31785023
57Leukodystrophy (HP:0002415)2.30137800
58Abnormality of fatty-acid metabolism (HP:0004359)2.29678166
59Abnormal lung lobation (HP:0002101)2.29587222
60Abnormality of pyrimidine metabolism (HP:0004353)2.28853072
61Abnormality of the preputium (HP:0100587)2.25331013
62Reduced antithrombin III activity (HP:0001976)2.25034191
63Chromsome breakage (HP:0040012)2.25033939
64Respiratory difficulties (HP:0002880)2.24952651
65Conjunctival hamartoma (HP:0100780)2.24886125
66Abnormality of serum amino acid levels (HP:0003112)2.24719093
67Neoplasm of the adrenal gland (HP:0100631)2.23645362
6811 pairs of ribs (HP:0000878)2.22158183
69Exertional dyspnea (HP:0002875)2.21474455
70Abnormality of chromosome stability (HP:0003220)2.19990257
71Petechiae (HP:0000967)2.19889444
72Increased intramyocellular lipid droplets (HP:0012240)2.19135734
73Renal cortical cysts (HP:0000803)2.19038724
74Hypobetalipoproteinemia (HP:0003563)2.18865952
75Abnormality of the fetal cardiovascular system (HP:0010948)2.18413999
76Abnormal umbilical cord blood vessels (HP:0011403)2.18413999
77Single umbilical artery (HP:0001195)2.18413999
78Abnormality of the umbilical cord (HP:0010881)2.18277269
79CNS demyelination (HP:0007305)2.18135021
80Hyperalaninemia (HP:0003348)2.17929510
81Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.17929510
82Abnormality of alanine metabolism (HP:0010916)2.17929510
83Aplasia/Hypoplasia affecting the retina (HP:0008061)2.16562051
843-Methylglutaconic aciduria (HP:0003535)2.16281646
85Carpal bone hypoplasia (HP:0001498)2.12970543
86Abnormality of sulfur amino acid metabolism (HP:0004339)2.12862083
87Palpitations (HP:0001962)2.12689124
88Posterior subcapsular cataract (HP:0007787)2.12648081
89Pancytopenia (HP:0001876)2.11954751
90Dicarboxylic aciduria (HP:0003215)2.11603173
91Abnormality of dicarboxylic acid metabolism (HP:0010995)2.11603173
92Increased muscle lipid content (HP:0009058)2.10340393
93Premature graying of hair (HP:0002216)2.09944483
94Hypokinesia (HP:0002375)2.07886110
95Cerebral hypomyelination (HP:0006808)2.05581378
96Megaloblastic anemia (HP:0001889)2.05391192
97Bone marrow hypocellularity (HP:0005528)2.03987466
98Ragged-red muscle fibers (HP:0003200)2.03324091
99Methylmalonic aciduria (HP:0012120)2.02060717
100Abnormal trabecular bone morphology (HP:0100671)2.00613775
101Colon cancer (HP:0003003)2.00612703
102Abnormalities of placenta or umbilical cord (HP:0001194)1.99957881
103Abnormality of the duodenum (HP:0002246)1.97751581
104Irregular epiphyses (HP:0010582)1.97092908
105Macrocytic anemia (HP:0001972)1.97073031
106Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.96573686
107Abnormal protein N-linked glycosylation (HP:0012347)1.96573686
108Abnormal protein glycosylation (HP:0012346)1.96573686
109Abnormal glycosylation (HP:0012345)1.96573686
110Cellular immunodeficiency (HP:0005374)1.95971915
111Selective tooth agenesis (HP:0001592)1.95266547
112Lethargy (HP:0001254)1.93607992
113Chromosomal breakage induced by crosslinking agents (HP:0003221)1.93237673
114Myelodysplasia (HP:0002863)1.92776746
115Poor head control (HP:0002421)1.91981358
116Nephroblastoma (Wilms tumor) (HP:0002667)1.91537212
117Sparse eyelashes (HP:0000653)1.91152745
118Abnormality of the heme biosynthetic pathway (HP:0010472)1.90929717
119Abnormality of the vitamin B12 metabolism (HP:0004341)1.90192275
120Patellar aplasia (HP:0006443)1.89687781
121Congenital ichthyosiform erythroderma (HP:0007431)1.89016744
122Rhabdomyolysis (HP:0003201)1.88891916
123Cutaneous melanoma (HP:0012056)1.88791895
124Embryonal renal neoplasm (HP:0011794)1.87729328
125Gout (HP:0001997)1.87427238
126Meckel diverticulum (HP:0002245)1.86551961
127Hypoglycemic coma (HP:0001325)1.85681461
128Abnormality of placental membranes (HP:0011409)1.82729317
129Amniotic constriction ring (HP:0009775)1.82729317
130Aplasia/Hypoplasia of the sacrum (HP:0008517)1.80652685
131Abnormality of vitamin B metabolism (HP:0004340)1.80444607
132Gliosis (HP:0002171)1.78878272
133Lymphoma (HP:0002665)1.77365442
134Abnormality of the ileum (HP:0001549)1.75855330
135Renal Fanconi syndrome (HP:0001994)1.75117748
136Aplasia/Hypoplasia of the patella (HP:0006498)1.73925174
137Hypoplasia of the capital femoral epiphysis (HP:0003090)1.72561622

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EIF2AK13.98553348
2VRK23.80005234
3BUB13.64137589
4WEE13.25674548
5TSSK63.16575419
6NEK12.89904418
7EIF2AK32.71840686
8STK162.62215622
9CDC72.60604873
10NME22.36623887
11BRSK22.35738852
12TRIM282.05641995
13VRK11.98855651
14SRPK11.97830806
15MST1R1.96355958
16CCNB11.87269257
17ZAK1.75710466
18PIM21.75094565
19PLK41.70156160
20MYLK1.68964736
21TTK1.59540918
22ACVR1B1.58282634
23BCKDK1.51314630
24MST41.48531392
25BRSK11.40903427
26TESK21.40849506
27TESK11.40433118
28PLK11.38555985
29PLK31.37265294
30PASK1.36633945
31AURKB1.35642904
32NME11.34116778
33TAF11.31607517
34ATR1.28779394
35MKNK11.28561547
36STK241.21289652
37NEK21.18399263
38PDK31.18144885
39PDK41.18144885
40CDK81.12515431
41MAP4K11.10003812
42MAP3K121.09483263
43TEC1.05854782
44SMG11.05639280
45PBK1.04656024
46NEK91.04390541
47RPS6KB21.02558847
48PDK21.01955272
49TXK1.01946933
50CDK70.98807555
51RPS6KA40.98536313
52OBSCN0.96762741
53FLT30.96553710
54STK38L0.96451601
55KDR0.94479806
56MAP3K80.89903233
57EIF2AK20.89818490
58STK40.88896650
59IRAK40.86809673
60MKNK20.84925847
61BRAF0.84752539
62TGFBR10.84347601
63PAK40.83643689
64MAP2K30.83046707
65ZAP700.79715834
66AURKA0.77882038
67CDK40.77755889
68STK100.77250202
69SCYL20.76554043
70ALK0.75447811
71MAP3K30.74680539
72WNK30.74019931
73ARAF0.74011155
74MAP3K140.73876007
75PIM10.73858493
76IRAK30.73466018
77CSNK2A10.70804488
78EPHA20.70521306
79CHEK20.70409754
80BTK0.67924118
81CSNK1G30.67656818
82PLK20.64533634
83ILK0.63918966
84AKT30.63688601
85ERBB30.63131724
86MAP3K110.63064188
87MET0.62568409
88TAOK20.62011881
89DAPK10.60894412
90BMPR1B0.60203095
91ABL20.58865190
92STK390.58689106
93SIK30.57549989
94BLK0.57032359
95ERBB40.55372251
96TLK10.54078852
97CHEK10.54072006
98CSNK2A20.53989423
99CSNK1G10.52168874
100LMTK20.51240913
101TYK20.50831360
102PRKCI0.50686807
103NUAK10.50424394
104KIT0.48610788
105LRRK20.47634801
106LIMK10.47601876
107PAK10.46329101
108CLK10.44233605
109CSNK1A1L0.43699760
110OXSR10.43668189
111RPS6KA60.43173013
112STK30.43067325
113PRKG20.42402954
114JAK30.41267953
115DYRK30.41036647
116ATM0.40631968
117FER0.39534299
118RPS6KB10.39519744
119TNIK0.39056882
120CSNK1G20.38605504
121AKT20.37402974
122NEK60.35388646
123MAPKAPK30.32467903
124BCR0.31844401
125CDK10.31582592
126MAPKAPK50.30130807
127MELK0.29958389
128CDK60.29377325
129MARK30.29001394
130FGFR10.25503445
131CDK20.24618269
132CDK90.23057940
133CSNK1E0.20734948

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.40932426
2Proteasome_Homo sapiens_hsa030504.14624867
3Mismatch repair_Homo sapiens_hsa034303.62560568
4Citrate cycle (TCA cycle)_Homo sapiens_hsa000203.00208195
5Ribosome_Homo sapiens_hsa030102.79521803
6RNA polymerase_Homo sapiens_hsa030202.77030112
7Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.70183100
8Base excision repair_Homo sapiens_hsa034102.59541779
9Homologous recombination_Homo sapiens_hsa034402.49269538
10Pyrimidine metabolism_Homo sapiens_hsa002402.37761818
11Nucleotide excision repair_Homo sapiens_hsa034202.35255985
12Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.22125319
13One carbon pool by folate_Homo sapiens_hsa006702.18011876
14Spliceosome_Homo sapiens_hsa030402.17653147
15RNA transport_Homo sapiens_hsa030132.07229965
16Oxidative phosphorylation_Homo sapiens_hsa001902.03922777
172-Oxocarboxylic acid metabolism_Homo sapiens_hsa012102.02112847
18Parkinsons disease_Homo sapiens_hsa050121.94138010
19Cell cycle_Homo sapiens_hsa041101.71620360
20Non-homologous end-joining_Homo sapiens_hsa034501.65174640
21Carbon metabolism_Homo sapiens_hsa012001.62178641
22RNA degradation_Homo sapiens_hsa030181.49102008
23Protein export_Homo sapiens_hsa030601.47056570
24Pentose phosphate pathway_Homo sapiens_hsa000301.45708238
25Huntingtons disease_Homo sapiens_hsa050161.43722394
26Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.39205414
27Biosynthesis of amino acids_Homo sapiens_hsa012301.36022802
28Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.35335584
29Fanconi anemia pathway_Homo sapiens_hsa034601.32482111
30Purine metabolism_Homo sapiens_hsa002301.31672003
31Cysteine and methionine metabolism_Homo sapiens_hsa002701.31624477
32Drug metabolism - other enzymes_Homo sapiens_hsa009831.31206799
33Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.28964125
34Basal transcription factors_Homo sapiens_hsa030221.22805491
35Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.15505641
36Cyanoamino acid metabolism_Homo sapiens_hsa004601.15500636
37Folate biosynthesis_Homo sapiens_hsa007901.14123652
38Fructose and mannose metabolism_Homo sapiens_hsa000511.13926385
39Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.13234356
40Glutathione metabolism_Homo sapiens_hsa004801.10567822
41Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.10148616
42Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.08693122
43Pyruvate metabolism_Homo sapiens_hsa006201.08219190
44Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.07715382
45Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.06147516
46Alzheimers disease_Homo sapiens_hsa050101.03895634
47Legionellosis_Homo sapiens_hsa051341.00707288
48Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.98034953
49Galactose metabolism_Homo sapiens_hsa000520.96512764
50Selenocompound metabolism_Homo sapiens_hsa004500.91595208
51p53 signaling pathway_Homo sapiens_hsa041150.89984819
52Propanoate metabolism_Homo sapiens_hsa006400.89555892
53Antigen processing and presentation_Homo sapiens_hsa046120.88686571
54Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.87745583
55Steroid biosynthesis_Homo sapiens_hsa001000.86096360
56Epstein-Barr virus infection_Homo sapiens_hsa051690.81813380
57Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.79100755
58Fatty acid metabolism_Homo sapiens_hsa012120.68276799
59Fat digestion and absorption_Homo sapiens_hsa049750.67755588
60Pentose and glucuronate interconversions_Homo sapiens_hsa000400.67572566
61Sulfur metabolism_Homo sapiens_hsa009200.66239126
62Metabolic pathways_Homo sapiens_hsa011000.65870742
63mRNA surveillance pathway_Homo sapiens_hsa030150.62725078
64Herpes simplex infection_Homo sapiens_hsa051680.60762363
65Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.60042023
66Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.59272364
67Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.59147023
68Sulfur relay system_Homo sapiens_hsa041220.58848859
69Arginine biosynthesis_Homo sapiens_hsa002200.58515734
70Oocyte meiosis_Homo sapiens_hsa041140.58467064
71Renin-angiotensin system_Homo sapiens_hsa046140.56481796
72Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.56036591
73Peroxisome_Homo sapiens_hsa041460.52565014
74N-Glycan biosynthesis_Homo sapiens_hsa005100.51895403
75Fatty acid degradation_Homo sapiens_hsa000710.46698281
76Primary immunodeficiency_Homo sapiens_hsa053400.45540336
77beta-Alanine metabolism_Homo sapiens_hsa004100.44480888
78Other glycan degradation_Homo sapiens_hsa005110.42689967
79Caffeine metabolism_Homo sapiens_hsa002320.41351352
80Arachidonic acid metabolism_Homo sapiens_hsa005900.41219435
81Tryptophan metabolism_Homo sapiens_hsa003800.40358276
82Vitamin B6 metabolism_Homo sapiens_hsa007500.39779214
83Butanoate metabolism_Homo sapiens_hsa006500.39722739
84Systemic lupus erythematosus_Homo sapiens_hsa053220.37832689
85Cardiac muscle contraction_Homo sapiens_hsa042600.37010002
86Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.35268690
87Mineral absorption_Homo sapiens_hsa049780.34619018
88Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.33908440
89Regulation of autophagy_Homo sapiens_hsa041400.33153472
90Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.32477832
91Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.32270732
92Vitamin digestion and absorption_Homo sapiens_hsa049770.32210661
93Vibrio cholerae infection_Homo sapiens_hsa051100.31678223
94Type I diabetes mellitus_Homo sapiens_hsa049400.31239116
95Starch and sucrose metabolism_Homo sapiens_hsa005000.31025989
96Allograft rejection_Homo sapiens_hsa053300.30530613
97Retinol metabolism_Homo sapiens_hsa008300.30127061
98Measles_Homo sapiens_hsa051620.29696519
99Phenylalanine metabolism_Homo sapiens_hsa003600.28767263
100Viral carcinogenesis_Homo sapiens_hsa052030.28727706
101Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.28620459
102Intestinal immune network for IgA production_Homo sapiens_hsa046720.26802982
103Thyroid cancer_Homo sapiens_hsa052160.25036935
104Collecting duct acid secretion_Homo sapiens_hsa049660.24992027
105Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.24052561
106Apoptosis_Homo sapiens_hsa042100.23067065
107Arginine and proline metabolism_Homo sapiens_hsa003300.23013052
108Graft-versus-host disease_Homo sapiens_hsa053320.21990090
109Fatty acid elongation_Homo sapiens_hsa000620.21686545
110Primary bile acid biosynthesis_Homo sapiens_hsa001200.21642451
111Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.21378268
112RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.19247929
113Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.18784856
114Steroid hormone biosynthesis_Homo sapiens_hsa001400.18487053
115Influenza A_Homo sapiens_hsa051640.18474749
116Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.17028859
117Chemical carcinogenesis_Homo sapiens_hsa052040.16007243
118Tyrosine metabolism_Homo sapiens_hsa003500.14116332
119Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.14071894
120Hematopoietic cell lineage_Homo sapiens_hsa046400.13997830
121Sphingolipid metabolism_Homo sapiens_hsa006000.13765289
122NF-kappa B signaling pathway_Homo sapiens_hsa040640.12506060
123Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.12172927

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