SLC25A53

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1platelet dense granule organization (GO:0060155)4.11983083
2L-fucose catabolic process (GO:0042355)4.03383305
3fucose catabolic process (GO:0019317)4.03383305
4L-fucose metabolic process (GO:0042354)4.03383305
5eosinophil chemotaxis (GO:0048245)4.01889251
6signal peptide processing (GO:0006465)4.00499035
7negative regulation of cytosolic calcium ion concentration (GO:0051481)3.90837027
8behavioral response to nicotine (GO:0035095)3.87140683
9cellular ketone body metabolic process (GO:0046950)3.83383405
10positive regulation of synaptic transmission, GABAergic (GO:0032230)3.82621829
11negative regulation of synaptic transmission, GABAergic (GO:0032229)3.81661503
12DNA double-strand break processing (GO:0000729)3.76937766
13DNA deamination (GO:0045006)3.75994153
14mechanosensory behavior (GO:0007638)3.75316198
15regulation of hexokinase activity (GO:1903299)3.62934963
16regulation of glucokinase activity (GO:0033131)3.62934963
17eosinophil migration (GO:0072677)3.48150985
18synaptic vesicle exocytosis (GO:0016079)3.42350604
19negative regulation of cell killing (GO:0031342)3.42084432
20negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.42084432
21ketone body metabolic process (GO:1902224)3.41631769
22neuron cell-cell adhesion (GO:0007158)3.40544087
23detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.38761772
24respiratory chain complex IV assembly (GO:0008535)3.35865287
25regulation of synaptic vesicle exocytosis (GO:2000300)3.34756375
26indolalkylamine metabolic process (GO:0006586)3.34268672
27negative regulation of DNA-dependent DNA replication (GO:2000104)3.34251162
28negative regulation of translation, ncRNA-mediated (GO:0040033)3.33851984
29regulation of translation, ncRNA-mediated (GO:0045974)3.33851984
30negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.33851984
31adaptation of signaling pathway (GO:0023058)3.26111463
32somatic hypermutation of immunoglobulin genes (GO:0016446)3.24432062
33somatic diversification of immune receptors via somatic mutation (GO:0002566)3.24432062
34water-soluble vitamin biosynthetic process (GO:0042364)3.22426761
35protein localization to synapse (GO:0035418)3.21570715
36epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.17761853
37replication fork processing (GO:0031297)3.17005397
38tryptophan catabolic process (GO:0006569)3.13683105
39indole-containing compound catabolic process (GO:0042436)3.13683105
40indolalkylamine catabolic process (GO:0046218)3.13683105
41neuron remodeling (GO:0016322)3.13209576
42positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.13200757
43regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.12583722
44regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.07720502
45auditory behavior (GO:0031223)3.04565974
46cilium morphogenesis (GO:0060271)3.04464537
47cytochrome complex assembly (GO:0017004)3.02910637
48presynaptic membrane assembly (GO:0097105)3.02344455
49regulation of short-term neuronal synaptic plasticity (GO:0048172)3.00255907
50peptidyl-histidine modification (GO:0018202)2.99318303
51behavioral response to ethanol (GO:0048149)2.96917095
52protein K11-linked deubiquitination (GO:0035871)2.96644470
53regulation of synaptic vesicle transport (GO:1902803)2.94467644
54recombinational repair (GO:0000725)2.94375730
55double-strand break repair via homologous recombination (GO:0000724)2.93637152
56preassembly of GPI anchor in ER membrane (GO:0016254)2.93574576
57presynaptic membrane organization (GO:0097090)2.91320757
58kynurenine metabolic process (GO:0070189)2.89946598
59positive regulation of amino acid transport (GO:0051957)2.89343172
60postsynaptic membrane organization (GO:0001941)2.89314606
61regulation of memory T cell differentiation (GO:0043380)2.89014595
62protein prenylation (GO:0018342)2.88488028
63prenylation (GO:0097354)2.88488028
64regulation of synaptic transmission, GABAergic (GO:0032228)2.88275038
65response to auditory stimulus (GO:0010996)2.85366026
66tryptophan metabolic process (GO:0006568)2.84504717
67innervation (GO:0060384)2.84356961
68protein complex biogenesis (GO:0070271)2.83563611
69B cell receptor signaling pathway (GO:0050853)2.81703605
70kidney morphogenesis (GO:0060993)2.81658418
71regulation of platelet aggregation (GO:0090330)2.81287160
72detection of light stimulus involved in sensory perception (GO:0050962)2.80927569
73detection of light stimulus involved in visual perception (GO:0050908)2.80927569
74protein polyglutamylation (GO:0018095)2.79589554
75dopamine transport (GO:0015872)2.79123066
76nonmotile primary cilium assembly (GO:0035058)2.79031368
77adult feeding behavior (GO:0008343)2.78325956
78glycine transport (GO:0015816)2.77683145
79anterograde synaptic vesicle transport (GO:0048490)2.76677083
80epithelial cilium movement (GO:0003351)2.75596128
81photoreceptor cell maintenance (GO:0045494)2.75532042
82neuron maturation (GO:0042551)2.75116560
83locomotory exploration behavior (GO:0035641)2.74782911
84interferon-gamma production (GO:0032609)2.74028543
85regulation of glutamate receptor signaling pathway (GO:1900449)2.73771330
86cilium organization (GO:0044782)2.73309464
87negative regulation of telomere maintenance (GO:0032205)2.73135424
88cerebellar Purkinje cell differentiation (GO:0021702)2.72651770
89vocalization behavior (GO:0071625)2.72585151
90regulation of vesicle fusion (GO:0031338)2.72468591
91protein-cofactor linkage (GO:0018065)2.71935490
92reciprocal meiotic recombination (GO:0007131)2.71740152
93reciprocal DNA recombination (GO:0035825)2.71740152
94protein neddylation (GO:0045116)2.69951725
95positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.69659476
96gamma-aminobutyric acid signaling pathway (GO:0007214)2.69008144
97startle response (GO:0001964)2.68714523
98piRNA metabolic process (GO:0034587)2.68343105
99cilium assembly (GO:0042384)2.66337933
100righting reflex (GO:0060013)2.64828165
101regulation of cilium movement (GO:0003352)2.64385754
102regulation of protein glycosylation (GO:0060049)2.63481168
103cellular response to interleukin-15 (GO:0071350)2.61276444
104response to pheromone (GO:0019236)2.60282383
105reflex (GO:0060004)2.59345460
106amine catabolic process (GO:0009310)2.58952517
107cellular biogenic amine catabolic process (GO:0042402)2.58952517
108regulation of nuclear cell cycle DNA replication (GO:0033262)2.58591913
109positive regulation of synapse assembly (GO:0051965)2.58331078
110regulation of synapse assembly (GO:0051963)2.58132458
111oxygen transport (GO:0015671)2.57916251
112mitochondrial respiratory chain complex assembly (GO:0033108)2.57242257
113lactate metabolic process (GO:0006089)2.56777781
114endocrine pancreas development (GO:0031018)2.56762275
115intraciliary transport (GO:0042073)2.56075200
116nitric oxide mediated signal transduction (GO:0007263)2.55277116
117neural tube formation (GO:0001841)2.55273729
118nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.53610774
119mannosylation (GO:0097502)2.53546736
120protein localization to cilium (GO:0061512)2.53370268
121synaptic transmission, glutamatergic (GO:0035249)2.53301633
122long-term synaptic potentiation (GO:0060291)2.52610070
123neurotransmitter-gated ion channel clustering (GO:0072578)2.52453529
124maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.51930360
125synaptic vesicle maturation (GO:0016188)2.51660516
126neuronal action potential (GO:0019228)2.50257415
127glutamate secretion (GO:0014047)2.50035676
128negative regulation of protein oligomerization (GO:0032460)2.49988420
129negative regulation of execution phase of apoptosis (GO:1900118)2.49953227
130somite rostral/caudal axis specification (GO:0032525)2.49342290
131neuron-neuron synaptic transmission (GO:0007270)2.48128042
132ionotropic glutamate receptor signaling pathway (GO:0035235)2.47275978
133DNA catabolic process, exonucleolytic (GO:0000738)2.47043101
134cyclic nucleotide catabolic process (GO:0009214)2.46265269
135exploration behavior (GO:0035640)2.46114123
136regulation of synaptic transmission, glutamatergic (GO:0051966)2.45870903
137regulation of B cell receptor signaling pathway (GO:0050855)2.45718179
138glutamate receptor signaling pathway (GO:0007215)2.45304284
139negative regulation of calcium ion-dependent exocytosis (GO:0045955)2.45242040
140negative regulation of dendrite development (GO:2000171)2.44808765
141synapsis (GO:0007129)2.44676111
142positive regulation of insulin secretion involved in cellular response to glucose stimulus (GO:003572.44675046
143positive regulation of gamma-delta T cell activation (GO:0046645)2.44511587
144indole-containing compound metabolic process (GO:0042430)2.42558661
145regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.41987509
146regulation of mitotic spindle checkpoint (GO:1903504)2.41987509
147regulation of neurotransmitter secretion (GO:0046928)2.41844045
148C4-dicarboxylate transport (GO:0015740)2.41778219
149neurotransmitter secretion (GO:0007269)2.41744435
150somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)2.41497818
151somatic diversification of immunoglobulins involved in immune response (GO:0002208)2.41497818
152isotype switching (GO:0045190)2.41497818
153proline transport (GO:0015824)2.41425574
154cAMP catabolic process (GO:0006198)2.41121861
155regulation of isotype switching to IgG isotypes (GO:0048302)2.39731201
156regulation of neurotransmitter uptake (GO:0051580)2.39701630
157tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)2.39260334
158RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)2.39260334
159regulation of uterine smooth muscle contraction (GO:0070472)2.38759763
160cerebellum development (GO:0021549)2.36889128
161centriole replication (GO:0007099)2.36784147
162neuromuscular synaptic transmission (GO:0007274)2.36773981
163glycosphingolipid biosynthetic process (GO:0006688)2.36609932
164RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.35108569
165negative regulation of mast cell activation (GO:0033004)2.35048167
166regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.33718492
167transmission of nerve impulse (GO:0019226)2.33640792
168positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.33159132
169neuron fate specification (GO:0048665)2.32461780
170regulation of pigment cell differentiation (GO:0050932)2.32359989
171neuron recognition (GO:0008038)2.32206340
172regulation of penile erection (GO:0060405)2.32203577
173vesicle docking involved in exocytosis (GO:0006904)2.31407055
174B cell proliferation (GO:0042100)2.30944984
175membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.30924996
176regulation of catecholamine metabolic process (GO:0042069)2.27572432
177regulation of dopamine metabolic process (GO:0042053)2.27572432
178negative regulation of dendrite morphogenesis (GO:0050774)2.26251425
179cell differentiation in hindbrain (GO:0021533)2.25228922
180membrane depolarization during action potential (GO:0086010)2.24610172
181T cell lineage commitment (GO:0002360)2.24095553
182axoneme assembly (GO:0035082)2.22848701
183detection of calcium ion (GO:0005513)2.22047678
184response to interleukin-15 (GO:0070672)2.21213250
185insulin secretion (GO:0030073)2.20678090
186negative regulation of antigen receptor-mediated signaling pathway (GO:0050858)2.20611434
187lysosome localization (GO:0032418)2.20320084
188histamine secretion (GO:0001821)2.19137610
189regulation of neurotransmitter transport (GO:0051588)2.19037740
190vesicle docking (GO:0048278)2.19031624
191long-term memory (GO:0007616)2.18383523
192G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.17660350
193synaptic vesicle transport (GO:0048489)2.16390948
194establishment of synaptic vesicle localization (GO:0097480)2.16390948
195regulation of axon regeneration (GO:0048679)2.16289962
196regulation of neuron projection regeneration (GO:0070570)2.16289962

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.96435287
2GBX2_23144817_ChIP-Seq_PC3_Human3.66899403
3ZNF274_21170338_ChIP-Seq_K562_Hela3.40989161
4SMAD_19615063_ChIP-ChIP_OVARY_Human2.97918365
5ZFP57_27257070_Chip-Seq_ESCs_Mouse2.58315636
6TAF15_26573619_Chip-Seq_HEK293_Human2.58229287
7IGF1R_20145208_ChIP-Seq_DFB_Human2.45099903
8JARID2_20064375_ChIP-Seq_MESCs_Mouse2.37507313
9GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.34846405
10SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.32624889
11FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.31257196
12SALL1_21062744_ChIP-ChIP_HESCs_Human2.19413506
13HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.18367558
14HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.16784052
15BMI1_23680149_ChIP-Seq_NPCS_Mouse2.11495820
16P300_19829295_ChIP-Seq_ESCs_Human2.11243359
17REST_21632747_ChIP-Seq_MESCs_Mouse2.11136623
18GABP_17652178_ChIP-ChIP_JURKAT_Human2.04901461
19POU3F2_20337985_ChIP-ChIP_501MEL_Human2.04355868
20KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.98421828
21SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.92160633
22SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.90812599
23EST1_17652178_ChIP-ChIP_JURKAT_Human1.90179078
24FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.89741577
25E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.88993663
26EZH2_27304074_Chip-Seq_ESCs_Mouse1.88976323
27SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.88788464
28PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.88594331
29SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.88280760
30TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.85564093
31MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.84197540
32AR_21572438_ChIP-Seq_LNCaP_Human1.84123768
33CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.82690612
34BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.82280339
35SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.80881441
36NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.79299379
37BCAT_22108803_ChIP-Seq_LS180_Human1.77136780
38JARID2_20075857_ChIP-Seq_MESCs_Mouse1.76042305
39CTBP1_25329375_ChIP-Seq_LNCAP_Human1.74857932
40CTBP2_25329375_ChIP-Seq_LNCAP_Human1.72730311
41FUS_26573619_Chip-Seq_HEK293_Human1.71854133
42OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.69514980
43RNF2_27304074_Chip-Seq_NSC_Mouse1.68660272
44EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.68592855
45EED_16625203_ChIP-ChIP_MESCs_Mouse1.66628561
46SMAD4_21799915_ChIP-Seq_A2780_Human1.65697038
47SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.64611256
48REST_18959480_ChIP-ChIP_MESCs_Mouse1.62699697
49IKZF1_21737484_ChIP-ChIP_HCT116_Human1.62012838
50RNF2_27304074_Chip-Seq_ESCs_Mouse1.61717193
51VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.60769206
52NANOG_18555785_Chip-Seq_ESCs_Mouse1.60550447
53ELK1_19687146_ChIP-ChIP_HELA_Human1.57652406
54EZH2_18974828_ChIP-Seq_MESCs_Mouse1.56986909
55RNF2_18974828_ChIP-Seq_MESCs_Mouse1.56986909
56ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.55092877
57IRF1_19129219_ChIP-ChIP_H3396_Human1.52838079
58CBX2_27304074_Chip-Seq_ESCs_Mouse1.52125473
59CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.51504136
60TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.51403310
61SUZ12_27294783_Chip-Seq_ESCs_Mouse1.50324268
62MTF2_20144788_ChIP-Seq_MESCs_Mouse1.49842882
63VDR_22108803_ChIP-Seq_LS180_Human1.49664450
64FLI1_27457419_Chip-Seq_LIVER_Mouse1.49418469
65UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.48970499
66EZH2_27294783_Chip-Seq_ESCs_Mouse1.48630841
67CBP_20019798_ChIP-Seq_JUKART_Human1.48077010
68IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.48077010
69NANOG_19829295_ChIP-Seq_ESCs_Human1.44093942
70SOX2_19829295_ChIP-Seq_ESCs_Human1.44093942
71TP53_22573176_ChIP-Seq_HFKS_Human1.43908767
72PCGF2_27294783_Chip-Seq_ESCs_Mouse1.43611710
73MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.42933229
74NOTCH1_21737748_ChIP-Seq_TLL_Human1.42035902
75POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.41580983
76TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.41580983
77EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.39803222
78CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.39787580
79STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.39094627
80STAT3_23295773_ChIP-Seq_U87_Human1.38999146
81EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.37193665
82TCF4_22108803_ChIP-Seq_LS180_Human1.35991937
83GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.35771662
84MYC_18940864_ChIP-ChIP_HL60_Human1.35066843
85EWS_26573619_Chip-Seq_HEK293_Human1.34362622
86SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.34015792
87TOP2B_26459242_ChIP-Seq_MCF-7_Human1.33775591
88P53_22387025_ChIP-Seq_ESCs_Mouse1.33702695
89E2F1_18555785_Chip-Seq_ESCs_Mouse1.32386072
90RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.32293974
91SMAD3_21741376_ChIP-Seq_EPCs_Human1.31943801
92CMYC_18555785_Chip-Seq_ESCs_Mouse1.30818893
93SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.28734090
94VDR_23849224_ChIP-Seq_CD4+_Human1.28307859
95FOXA1_25329375_ChIP-Seq_VCAP_Human1.28039147
96FOXA1_27270436_Chip-Seq_PROSTATE_Human1.28039147
97PIAS1_25552417_ChIP-Seq_VCAP_Human1.26856861
98SUZ12_18555785_Chip-Seq_ESCs_Mouse1.26856201
99PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.26649858
100SUZ12_27294783_Chip-Seq_NPCs_Mouse1.26551853
101IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.24451559
102GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.23543145
103STAT3_18555785_Chip-Seq_ESCs_Mouse1.23205561
104NR3C1_21868756_ChIP-Seq_MCF10A_Human1.21333369
105AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.21005864
106CRX_20693478_ChIP-Seq_RETINA_Mouse1.20326505
107NMYC_18555785_Chip-Seq_ESCs_Mouse1.20295732
108CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.20064454
109MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.18750438
110SOX2_18555785_Chip-Seq_ESCs_Mouse1.18738519
111FOXA1_21572438_ChIP-Seq_LNCaP_Human1.18698241
112KLF5_20875108_ChIP-Seq_MESCs_Mouse1.17536445
113P300_18555785_Chip-Seq_ESCs_Mouse1.17438905
114NR3C1_23031785_ChIP-Seq_PC12_Mouse1.16097225
115FLI1_21867929_ChIP-Seq_TH2_Mouse1.15868977
116TCF4_23295773_ChIP-Seq_U87_Human1.15734867
117AR_25329375_ChIP-Seq_VCAP_Human1.13795313
118RUNX2_22187159_ChIP-Seq_PCA_Human1.12533945
119ER_23166858_ChIP-Seq_MCF-7_Human1.12290983
120NCOR_22424771_ChIP-Seq_293T_Human1.11591721
121TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.10584520
122EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.10552014
123TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.10339604
124RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.09700252
125NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.09671633
126CDX2_22108803_ChIP-Seq_LS180_Human1.09518865
127DROSHA_22980978_ChIP-Seq_HELA_Human1.08992264
128AR_20517297_ChIP-Seq_VCAP_Human1.08778454
129RARB_27405468_Chip-Seq_BRAIN_Mouse1.08742982
130NFE2_27457419_Chip-Seq_LIVER_Mouse1.08431502
131RUNX_20019798_ChIP-Seq_JUKART_Human1.07293249
132TAL1_26923725_Chip-Seq_HPCs_Mouse1.07245117
133SOX2_21211035_ChIP-Seq_LN229_Gbm1.07147000
134PCGF2_27294783_Chip-Seq_NPCs_Mouse1.05969027
135P53_22127205_ChIP-Seq_FIBROBLAST_Human1.05379516
136HTT_18923047_ChIP-ChIP_STHdh_Human1.05340471
137PRDM14_20953172_ChIP-Seq_ESCs_Human1.05186861
138RBPJ_22232070_ChIP-Seq_NCS_Mouse1.05062256
139EZH2_27294783_Chip-Seq_NPCs_Mouse1.03727357
140ETV2_25802403_ChIP-Seq_MESCs_Mouse1.03714856
141SRF_21415370_ChIP-Seq_HL-1_Mouse1.03053432
142OCT4_21477851_ChIP-Seq_ESCs_Mouse1.02904428
143TP63_19390658_ChIP-ChIP_HaCaT_Human1.02873735
144SMAD4_21741376_ChIP-Seq_EPCs_Human1.02252726
145SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.01547713
146YAP1_20516196_ChIP-Seq_MESCs_Mouse1.01410470
147LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.01363599
148GATA3_21878914_ChIP-Seq_MCF-7_Human1.00561679
149PADI4_21655091_ChIP-ChIP_MCF-7_Human0.97990444

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002837_dystrophic_cardiac_calcinosis3.17910061
2MP0003195_calcinosis3.15703054
3MP0003880_abnormal_central_pattern3.13855614
4MP0004859_abnormal_synaptic_plasticity3.05776260
5MP0005645_abnormal_hypothalamus_physiol2.99950924
6MP0001529_abnormal_vocalization2.79304435
7MP0001188_hyperpigmentation2.68624931
8MP0003787_abnormal_imprinting2.64990024
9MP0001968_abnormal_touch/_nociception2.57248320
10MP0002102_abnormal_ear_morphology2.43826198
11MP0003635_abnormal_synaptic_transmissio2.43073410
12MP0001986_abnormal_taste_sensitivity2.40566067
13MP0002735_abnormal_chemical_nociception2.36702037
14MP0003122_maternal_imprinting2.36133272
15MP0001984_abnormal_olfaction2.33897721
16MP0002736_abnormal_nociception_after2.30195207
17MP0009745_abnormal_behavioral_response2.29555095
18MP0002572_abnormal_emotion/affect_behav2.11290326
19MP0003183_abnormal_peptide_metabolism2.07838981
20MP0004270_analgesia2.05322918
21MP0002063_abnormal_learning/memory/cond2.04813432
22MP0006276_abnormal_autonomic_nervous2.03622057
23MP0008058_abnormal_DNA_repair1.99298756
24MP0002064_seizures1.95406708
25MP0002272_abnormal_nervous_system1.94171225
26MP0010386_abnormal_urinary_bladder1.93721013
27MP0002184_abnormal_innervation1.93472199
28MP0002734_abnormal_mechanical_nocicepti1.89580561
29MP0009046_muscle_twitch1.88325133
30MP0002822_catalepsy1.87034180
31MP0005409_darkened_coat_color1.84129709
32MP0006292_abnormal_olfactory_placode1.77963975
33MP0001486_abnormal_startle_reflex1.72744129
34MP0002638_abnormal_pupillary_reflex1.72028543
35MP0005671_abnormal_response_to1.71704418
36MP0005423_abnormal_somatic_nervous1.71252099
37MP0004147_increased_porphyrin_level1.69771798
38MP0005084_abnormal_gallbladder_morpholo1.69728725
39MP0008872_abnormal_physiological_respon1.68392451
40MP0001970_abnormal_pain_threshold1.68200364
41MP0002557_abnormal_social/conspecific_i1.66286578
42MP0002067_abnormal_sensory_capabilities1.64477997
43MP0003283_abnormal_digestive_organ1.63433640
44MP0001790_abnormal_immune_system1.62282798
45MP0005387_immune_system_phenotype1.62282798
46MP0002733_abnormal_thermal_nociception1.61093880
47MP0000427_abnormal_hair_cycle1.59532023
48MP0003121_genomic_imprinting1.59333862
49MP0000778_abnormal_nervous_system1.57345628
50MP0005646_abnormal_pituitary_gland1.54779670
51MP0001502_abnormal_circadian_rhythm1.53692278
52MP0008569_lethality_at_weaning1.53409369
53MP0000372_irregular_coat_pigmentation1.51714598
54MP0001485_abnormal_pinna_reflex1.51276482
55MP0005379_endocrine/exocrine_gland_phen1.44747641
56MP0002653_abnormal_ependyma_morphology1.41352572
57MP0004133_heterotaxia1.39169923
58MP0000955_abnormal_spinal_cord1.38328242
59MP0002751_abnormal_autonomic_nervous1.37993171
60MP0000631_abnormal_neuroendocrine_gland1.37992724
61MP0008875_abnormal_xenobiotic_pharmacok1.34108782
62MP0005075_abnormal_melanosome_morpholog1.32935324
63MP0002876_abnormal_thyroid_physiology1.32837248
64MP0006072_abnormal_retinal_apoptosis1.31721679
65MP0003011_delayed_dark_adaptation1.31323454
66MP0004742_abnormal_vestibular_system1.28370152
67MP0001905_abnormal_dopamine_level1.26862818
68MP0002277_abnormal_respiratory_mucosa1.26230901
69MP0002928_abnormal_bile_duct1.23677560
70MP0004811_abnormal_neuron_physiology1.23443882
71MP0002938_white_spotting1.22366325
72MP0004043_abnormal_pH_regulation1.21341841
73MP0001800_abnormal_humoral_immune1.21239505
74MP0000569_abnormal_digit_pigmentation1.21136004
75MP0005386_behavior/neurological_phenoty1.19871102
76MP0004924_abnormal_behavior1.19871102
77MP0001501_abnormal_sleep_pattern1.18580417
78MP0003718_maternal_effect1.18495603
79MP0008789_abnormal_olfactory_epithelium1.17376374
80MP0009780_abnormal_chondrocyte_physiolo1.16996476
81MP0000015_abnormal_ear_pigmentation1.16886023
82MP0005394_taste/olfaction_phenotype1.13580041
83MP0005499_abnormal_olfactory_system1.13580041
84MP0000013_abnormal_adipose_tissue1.10862528
85MP0008961_abnormal_basal_metabolism1.08990986
86MP0002882_abnormal_neuron_morphology1.08870676
87MP0002909_abnormal_adrenal_gland1.07676679
88MP0005174_abnormal_tail_pigmentation1.06203687
89MP0001764_abnormal_homeostasis1.05246831
90MP0010094_abnormal_chromosome_stability1.04814465
91MP0005389_reproductive_system_phenotype1.04365645
92MP0005085_abnormal_gallbladder_physiolo1.04236366
93MP0001440_abnormal_grooming_behavior1.02850246
94MP0008057_abnormal_DNA_replication1.02777077
95MP0002095_abnormal_skin_pigmentation1.01936760
96MP0001835_abnormal_antigen_presentation1.01681515
97MP0001944_abnormal_pancreas_morphology1.01647549
98MP0004142_abnormal_muscle_tone1.00215375
99MP0003763_abnormal_thymus_physiology1.00065158
100MP0005220_abnormal_exocrine_pancreas0.98880526
101MP0003136_yellow_coat_color0.97001521
102MP0003646_muscle_fatigue0.96770938
103MP0004215_abnormal_myocardial_fiber0.96337150
104MP0005551_abnormal_eye_electrophysiolog0.96173296
105MP0003890_abnormal_embryonic-extraembry0.95499765
106MP0004885_abnormal_endolymph0.94281480
107MP0002693_abnormal_pancreas_physiology0.93762353
108MP0002066_abnormal_motor_capabilities/c0.93463541
109MP0000383_abnormal_hair_follicle0.92902027
110MP0006036_abnormal_mitochondrial_physio0.92705369
111MP0002234_abnormal_pharynx_morphology0.92036882
112MP0008260_abnormal_autophagy0.89621679
113MP0003186_abnormal_redox_activity0.88655720
114MP0001919_abnormal_reproductive_system0.88597997
115MP0003633_abnormal_nervous_system0.85919720
116MP0001929_abnormal_gametogenesis0.85733379
117MP0008995_early_reproductive_senescence0.85731472
118MP0002723_abnormal_immune_serum0.85478998
119MP0000230_abnormal_systemic_arterial0.85253362
120MP0002163_abnormal_gland_morphology0.85182618
121MP0005332_abnormal_amino_acid0.84062020
122MP0002420_abnormal_adaptive_immunity0.83383804
123MP0000516_abnormal_urinary_system0.83301552
124MP0005367_renal/urinary_system_phenotyp0.83301552
125MP0002152_abnormal_brain_morphology0.82821135
126MP0002398_abnormal_bone_marrow0.82687160
127MP0003252_abnormal_bile_duct0.82187502
128MP0001819_abnormal_immune_cell0.81127605
129MP0001299_abnormal_eye_distance/0.80864653
130MP0002138_abnormal_hepatobiliary_system0.80797015
131MP0008775_abnormal_heart_ventricle0.80217498
132MP0004510_myositis0.80119492
133MP0005636_abnormal_mineral_homeostasis0.79237411
134MP0002452_abnormal_antigen_presenting0.78794871
135MP0005000_abnormal_immune_tolerance0.78554970
136MP0003119_abnormal_digestive_system0.78215760
137MP0005253_abnormal_eye_physiology0.76547896
138MP0002069_abnormal_eating/drinking_beha0.75888569
139MP0002090_abnormal_vision0.75749221
140MP0002752_abnormal_somatic_nervous0.75672578
141MP0003698_abnormal_male_reproductive0.75458825
142MP0000716_abnormal_immune_system0.74883277
143MP0002229_neurodegeneration0.74190335
144MP0003959_abnormal_lean_body0.73531593
145MP0001963_abnormal_hearing_physiology0.70967376
146MP0003879_abnormal_hair_cell0.70088340
147MP0008877_abnormal_DNA_methylation0.68873588

Predicted human phenotypes

RankGene SetZ-score
1Pancreatic cysts (HP:0001737)3.99223022
2Febrile seizures (HP:0002373)3.97964047
3Abnormal hair whorl (HP:0010721)3.77529792
4Focal motor seizures (HP:0011153)3.60188674
5Epileptic encephalopathy (HP:0200134)3.30597056
6Type II lissencephaly (HP:0007260)3.29843710
7Protruding tongue (HP:0010808)3.21462532
8Nephronophthisis (HP:0000090)3.08668026
9Hypothermia (HP:0002045)2.97069695
10Ketoacidosis (HP:0001993)2.94607260
11Atonic seizures (HP:0010819)2.94151826
12Abnormality of the renal cortex (HP:0011035)2.91892968
13Progressive inability to walk (HP:0002505)2.89063268
14Progressive cerebellar ataxia (HP:0002073)2.82678405
15Hyperventilation (HP:0002883)2.70276854
16Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.67829839
17Methylmalonic acidemia (HP:0002912)2.66650921
18Agammaglobulinemia (HP:0004432)2.64994284
19Attenuation of retinal blood vessels (HP:0007843)2.62570494
20Myokymia (HP:0002411)2.61988087
21Nephrogenic diabetes insipidus (HP:0009806)2.61351774
22Abnormality of the renal medulla (HP:0100957)2.58660411
23Renal cortical cysts (HP:0000803)2.58449895
24Abolished electroretinogram (ERG) (HP:0000550)2.44911673
25Congenital, generalized hypertrichosis (HP:0004540)2.44847103
26Truncal ataxia (HP:0002078)2.44338054
27Sclerocornea (HP:0000647)2.41600526
28Medial flaring of the eyebrow (HP:0010747)2.41481497
29B lymphocytopenia (HP:0010976)2.39672660
30Abnormality of B cell number (HP:0010975)2.39672660
31Gait imbalance (HP:0002141)2.38957501
32Gaze-evoked nystagmus (HP:0000640)2.38410884
33Agitation (HP:0000713)2.37603604
34Polydipsia (HP:0001959)2.37335257
35Abnormal drinking behavior (HP:0030082)2.37335257
36Failure to thrive in infancy (HP:0001531)2.35730486
37Limb dystonia (HP:0002451)2.33958140
38Cystic liver disease (HP:0006706)2.32557052
39True hermaphroditism (HP:0010459)2.31718290
40Abnormality of the pancreatic islet cells (HP:0006476)2.28586290
41Abnormality of endocrine pancreas physiology (HP:0012093)2.28586290
42Pancreatic islet-cell hyperplasia (HP:0004510)2.25320176
43Drooling (HP:0002307)2.24445507
44Excessive salivation (HP:0003781)2.24445507
45Aplasia/Hypoplasia of the tongue (HP:0010295)2.24081558
46Abnormality of calcium-phosphate metabolism (HP:0100530)2.23679630
47Methylmalonic aciduria (HP:0012120)2.22534878
48Pendular nystagmus (HP:0012043)2.21638611
49Congenital primary aphakia (HP:0007707)2.20650764
50Ketosis (HP:0001946)2.20283719
51Absence seizures (HP:0002121)2.18981797
52Hypoglycemic coma (HP:0001325)2.17665237
53Progressive macrocephaly (HP:0004481)2.17485085
54Poor speech (HP:0002465)2.16419422
55Recurrent sinusitis (HP:0011108)2.16379641
56Abnormality of the ileum (HP:0001549)2.14875399
57Acute necrotizing encephalopathy (HP:0006965)2.13733061
58Male pseudohermaphroditism (HP:0000037)2.12008098
59Meningitis (HP:0001287)2.11036697
60Aplasia/Hypoplasia of the uvula (HP:0010293)2.10619249
61Postaxial foot polydactyly (HP:0001830)2.10352403
62Hip dysplasia (HP:0001385)2.10348270
63Mitochondrial inheritance (HP:0001427)2.10160673
64Gastrointestinal stroma tumor (HP:0100723)2.09793762
65Hypomagnesemia (HP:0002917)2.09156865
66Menstrual irregularities (HP:0000858)2.07664294
67Absent rod-and cone-mediated responses on ERG (HP:0007688)2.05037954
68Hyperinsulinemic hypoglycemia (HP:0000825)2.04034469
69Increased CSF lactate (HP:0002490)2.03343233
70Hemiparesis (HP:0001269)2.02607119
71Epileptiform EEG discharges (HP:0011182)2.02135983
72Hepatic necrosis (HP:0002605)2.01522287
73Abnormality of the labia minora (HP:0012880)2.01307048
74Focal seizures (HP:0007359)2.00927887
75Visual hallucinations (HP:0002367)1.99861841
76Meckel diverticulum (HP:0002245)1.98456617
77Hyperglycinemia (HP:0002154)1.97908951
78Abnormality of vitamin B metabolism (HP:0004340)1.97080826
79EEG with generalized epileptiform discharges (HP:0011198)1.96143170
80Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.95981397
81Abnormality of alanine metabolism (HP:0010916)1.95981397
82Hyperalaninemia (HP:0003348)1.95981397
83Acute encephalopathy (HP:0006846)1.95619576
84Furrowed tongue (HP:0000221)1.95533401
85Congenital hepatic fibrosis (HP:0002612)1.95143781
86Abnormality of binocular vision (HP:0011514)1.94666880
87Diplopia (HP:0000651)1.94666880
88White forelock (HP:0002211)1.94533070
89Abnormality of chromosome stability (HP:0003220)1.94013643
90Ependymoma (HP:0002888)1.91392596
91Thyroiditis (HP:0100646)1.91286218
92Chronic sinusitis (HP:0011109)1.91228569
93Panhypogammaglobulinemia (HP:0003139)1.91138672
94Tubular atrophy (HP:0000092)1.90727874
95Blue irides (HP:0000635)1.90674934
96T lymphocytopenia (HP:0005403)1.90492716
97Scanning speech (HP:0002168)1.89821714
98Aplasia/Hypoplasia of the lens (HP:0008063)1.87737131
99Lissencephaly (HP:0001339)1.87298678
100Colon cancer (HP:0003003)1.86630027
101Congenital sensorineural hearing impairment (HP:0008527)1.86122439
102Optic nerve hypoplasia (HP:0000609)1.85714349
103Inability to walk (HP:0002540)1.84970488
104Chronic hepatic failure (HP:0100626)1.84862029
105Thyroid-stimulating hormone excess (HP:0002925)1.84431989
106Hyperglycinuria (HP:0003108)1.83677067
107Bony spicule pigmentary retinopathy (HP:0007737)1.83193243
108Aplasia/Hypoplasia of the fovea (HP:0008060)1.83068461
109Hypoplasia of the fovea (HP:0007750)1.83068461
110Molar tooth sign on MRI (HP:0002419)1.82806459
111Abnormality of midbrain morphology (HP:0002418)1.82806459
112Anencephaly (HP:0002323)1.82675341
113Cerebellar dysplasia (HP:0007033)1.81990427
114Polyuria (HP:0000103)1.81828588
1153-Methylglutaconic aciduria (HP:0003535)1.81827551
116Abnormal rod and cone electroretinograms (HP:0008323)1.81228521
117Dialeptic seizures (HP:0011146)1.81153000
118Lipid accumulation in hepatocytes (HP:0006561)1.80963766
119Recurrent bronchitis (HP:0002837)1.80327904
120Hypsarrhythmia (HP:0002521)1.79692194
121Broad-based gait (HP:0002136)1.79562385
122Abnormality of the fingertips (HP:0001211)1.79379280
123Small epiphyses (HP:0010585)1.78454468
124Abnormal ciliary motility (HP:0012262)1.78187659
125Abnormality of the right ventricle (HP:0001707)1.77803509
126Genetic anticipation (HP:0003743)1.77296085
127Impaired smooth pursuit (HP:0007772)1.77183280
128Abnormality of salivation (HP:0100755)1.77142760
129Volvulus (HP:0002580)1.76516043
130Hepatocellular necrosis (HP:0001404)1.76034344
131Pancreatic fibrosis (HP:0100732)1.76031666
132Gastrointestinal atresia (HP:0002589)1.75856695
133Heterochromia iridis (HP:0001100)1.75591236
134IgM deficiency (HP:0002850)1.75240819
135Increased hepatocellular lipid droplets (HP:0006565)1.75051722
136Hypoproteinemia (HP:0003075)1.74601733
137Fair hair (HP:0002286)1.74164207
138Widely spaced teeth (HP:0000687)1.74097424
139Constricted visual fields (HP:0001133)1.73907132
140Growth hormone deficiency (HP:0000824)1.73701881
141Postaxial hand polydactyly (HP:0001162)1.72787392
142Hypoplasia of the capital femoral epiphysis (HP:0003090)1.71613816
143Abnormality of serine family amino acid metabolism (HP:0010894)1.71470643
144Abnormality of glycine metabolism (HP:0010895)1.71470643
145Exotropia (HP:0000577)1.71155182
146Poor coordination (HP:0002370)1.69466388
147Chromosomal breakage induced by crosslinking agents (HP:0003221)1.69314320
148Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.69301178
149Absent epiphyses (HP:0010577)1.69301178
150Congenital stationary night blindness (HP:0007642)1.69116149
151Disproportionate short-trunk short stature (HP:0003521)1.69070228
152Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.69060752
153Polyphagia (HP:0002591)1.68465809
154Hypoplasia of the pons (HP:0012110)1.68119306
155Abnormality of T cell number (HP:0011839)1.67651807
156Intestinal atresia (HP:0011100)1.67642845
157Dysautonomia (HP:0002459)1.65552393
158Depression (HP:0000716)1.64253032
159Irregular vertebral endplates (HP:0003301)1.63252006
160Vaginal atresia (HP:0000148)1.63052229
161Orthostatic hypotension (HP:0001278)1.62345106
162Genital tract atresia (HP:0001827)1.61584264
163Stereotypic behavior (HP:0000733)1.61535282
164Retinal dysplasia (HP:0007973)1.61373826
165Decreased central vision (HP:0007663)1.60739596
166Tented upper lip vermilion (HP:0010804)1.60479432
167Generalized tonic-clonic seizures (HP:0002069)1.58454379
168Abnormality of the vertebral endplates (HP:0005106)1.57165791
169Optic neuritis (HP:0100653)1.55935664
170Retrobulbar optic neuritis (HP:0100654)1.55935664
171Esotropia (HP:0000565)1.55685849
172Patchy hypopigmentation of hair (HP:0011365)1.53488193
173Large for gestational age (HP:0001520)1.53215024
174Open mouth (HP:0000194)1.52888271

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK6.21372730
2CASK3.42743250
3MAP4K23.28178246
4NTRK32.95359682
5TNIK2.63912900
6SIK32.38249478
7MAPK152.31921367
8MAPK132.31911843
9MAP2K72.31214888
10TXK2.16299943
11MAP3K122.13209029
12RIPK42.10858511
13BMPR22.00752300
14NUAK11.97612220
15ACVR1B1.91928418
16GRK11.87944611
17WNK31.85775064
18PINK11.84489894
19SIK21.79932947
20VRK21.77141911
21UHMK11.74668385
22MARK11.68835752
23TRIM281.66462248
24PRPF4B1.63006041
25VRK11.61152660
26HIPK21.59567599
27NTRK21.53738200
28EIF2AK31.51272303
29YES11.51133291
30PASK1.37278639
31TLK11.34824780
32MINK11.33614193
33INSRR1.29349079
34MUSK1.29235636
35FGFR21.28767045
36EPHA31.24247116
37NEK11.23376062
38TAOK31.22357353
39OXSR11.20354853
40MST41.19155951
41WNK41.16622983
42MAP3K41.15747811
43SYK1.15060698
44ERBB31.15052040
45PLK21.14221909
46DAPK11.13849957
47PLK31.13499697
48STK391.13342394
49GRK51.11604511
50CDK31.10979472
51CSNK1G11.09904029
52PNCK1.09585270
53ITK1.08735086
54SGK21.07167090
55MKNK11.05913981
56DYRK1A1.01771128
57SGK2231.00925610
58SGK4941.00925610
59TSSK61.00537251
60DYRK20.99034446
61MAP4K10.98918377
62PTK2B0.98715897
63AKT30.97238775
64MAP3K90.95967711
65MATK0.95608825
66JAK10.93479218
67CAMKK20.91335150
68CSNK1A1L0.90486741
69FES0.88515974
70MKNK20.86358680
71TEC0.84917690
72BRD40.83658536
73TAF10.83278268
74IRAK40.82960321
75ADRBK20.81743179
76CDK50.80492605
77STK30.80410123
78ZAK0.80285703
79CAMK2B0.80150385
80STK38L0.79336724
81BMPR1B0.78863968
82PRKCE0.78718070
83TGFBR10.78613906
84GRK70.76351354
85SGK30.73767761
86DAPK20.72504881
87NEK60.71496165
88EIF2AK10.71000797
89CDK190.69300449
90GRK60.67507812
91PLK40.66541204
92NTRK10.65415133
93MARK20.65194965
94EPHA40.65143794
95BRSK20.65019351
96NLK0.64400431
97RPS6KB10.63159145
98BTK0.62921890
99PHKG10.62626376
100PHKG20.62626376
101CLK10.62356045
102NME10.60511201
103IRAK10.58168495
104CSNK1G20.57411186
105PKN10.57024991
106PRKCG0.55901541
107SCYL20.54982765
108CCNB10.54811224
109MAPK70.54348358
110CSNK1G30.54293149
111STK160.54187895
112DYRK30.53401811
113CDC70.53240684
114PRKCH0.52936271
115WEE10.52130004
116FGR0.51281332
117EIF2AK20.50451401
118PRKCQ0.49449590
119FER0.49059707
120SGK10.48255847
121WNK10.48186662
122CDK80.48100492
123TIE10.46562090
124LYN0.46534385
125IKBKE0.45982604
126CAMK2A0.45678098
127CDC42BPA0.43005187
128ATR0.42157011
129PRKD30.41879056
130ATM0.41088109
131BCR0.41033465
132LCK0.40589964
133FYN0.39996166
134PIK3CA0.39562849
135SRPK10.39536757
136BRAF0.39242148
137IKBKB0.39169216
138CSK0.38927194
139ADRBK10.38922547
140MAP2K40.38805432
141STK110.38109282
142TNK20.37103748
143FGFR30.36807546
144PAK30.36747598
145PRKCI0.36301645
146CSNK1A10.35953889
147BCKDK0.35950381
148PRKACA0.35094527
149CAMK2D0.34818913
150PRKG10.34312618
151ERBB20.33214673
152CSNK1D0.32719318
153MAP2K60.30509375
154PLK10.29289728

Predicted pathways (KEGG)

RankGene SetZ-score
1Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.26469297
2Butanoate metabolism_Homo sapiens_hsa006502.80031166
3Nicotine addiction_Homo sapiens_hsa050332.74182911
4Olfactory transduction_Homo sapiens_hsa047402.40267324
5Oxidative phosphorylation_Homo sapiens_hsa001902.27584187
6Morphine addiction_Homo sapiens_hsa050322.21081058
7Homologous recombination_Homo sapiens_hsa034402.17195026
8Basal transcription factors_Homo sapiens_hsa030222.09374318
9Insulin secretion_Homo sapiens_hsa049112.08245931
10Fanconi anemia pathway_Homo sapiens_hsa034602.03843938
11Synaptic vesicle cycle_Homo sapiens_hsa047212.02562117
12GABAergic synapse_Homo sapiens_hsa047271.95213697
13Nitrogen metabolism_Homo sapiens_hsa009101.94046354
14RNA polymerase_Homo sapiens_hsa030201.91467228
15Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.86900729
16Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.85431026
17Circadian entrainment_Homo sapiens_hsa047131.81767888
18Propanoate metabolism_Homo sapiens_hsa006401.80509726
19Maturity onset diabetes of the young_Homo sapiens_hsa049501.73362871
20Glutamatergic synapse_Homo sapiens_hsa047241.71521118
21Parkinsons disease_Homo sapiens_hsa050121.69885108
22Taste transduction_Homo sapiens_hsa047421.61945989
23Tryptophan metabolism_Homo sapiens_hsa003801.58850243
24Dopaminergic synapse_Homo sapiens_hsa047281.55268126
25Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.54050769
26Primary immunodeficiency_Homo sapiens_hsa053401.53244637
27Serotonergic synapse_Homo sapiens_hsa047261.51723068
28Amphetamine addiction_Homo sapiens_hsa050311.50040276
29Linoleic acid metabolism_Homo sapiens_hsa005911.49126333
30Long-term potentiation_Homo sapiens_hsa047201.48005827
31Long-term depression_Homo sapiens_hsa047301.45356449
32Collecting duct acid secretion_Homo sapiens_hsa049661.44236868
33Protein export_Homo sapiens_hsa030601.44191793
34alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.43883887
35SNARE interactions in vesicular transport_Homo sapiens_hsa041301.41212146
36Peroxisome_Homo sapiens_hsa041461.40569770
37Proteasome_Homo sapiens_hsa030501.40566368
38Asthma_Homo sapiens_hsa053101.39447490
39Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.38770495
40Vibrio cholerae infection_Homo sapiens_hsa051101.37922201
41Cholinergic synapse_Homo sapiens_hsa047251.37088665
42One carbon pool by folate_Homo sapiens_hsa006701.37022318
43Selenocompound metabolism_Homo sapiens_hsa004501.36579096
44Cocaine addiction_Homo sapiens_hsa050301.34238430
45Type I diabetes mellitus_Homo sapiens_hsa049401.33330516
46Primary bile acid biosynthesis_Homo sapiens_hsa001201.32359290
47RNA degradation_Homo sapiens_hsa030181.28551679
48Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.28550554
49B cell receptor signaling pathway_Homo sapiens_hsa046621.26435544
50Renin secretion_Homo sapiens_hsa049241.20927156
51T cell receptor signaling pathway_Homo sapiens_hsa046601.16523008
52Calcium signaling pathway_Homo sapiens_hsa040201.13431476
53Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.13107540
54Aldosterone synthesis and secretion_Homo sapiens_hsa049251.12642846
55Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.12051448
56Salivary secretion_Homo sapiens_hsa049701.11131459
57Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.10711107
58Phosphatidylinositol signaling system_Homo sapiens_hsa040701.09921096
59Mismatch repair_Homo sapiens_hsa034301.06747499
60Steroid biosynthesis_Homo sapiens_hsa001001.06568333
61Oxytocin signaling pathway_Homo sapiens_hsa049211.06555228
62Sulfur metabolism_Homo sapiens_hsa009201.05890525
63Chemokine signaling pathway_Homo sapiens_hsa040621.04917875
64Caffeine metabolism_Homo sapiens_hsa002321.04794531
65Axon guidance_Homo sapiens_hsa043601.03281388
66Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.03102696
67Huntingtons disease_Homo sapiens_hsa050161.00694185
68beta-Alanine metabolism_Homo sapiens_hsa004100.99857440
69Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.99558052
70Non-homologous end-joining_Homo sapiens_hsa034500.99399860
71Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.97923637
72Intestinal immune network for IgA production_Homo sapiens_hsa046720.93978086
73Alzheimers disease_Homo sapiens_hsa050100.92596529
74Hematopoietic cell lineage_Homo sapiens_hsa046400.91271312
75Phototransduction_Homo sapiens_hsa047440.90269981
76Type II diabetes mellitus_Homo sapiens_hsa049300.90162951
77cAMP signaling pathway_Homo sapiens_hsa040240.88053522
78Purine metabolism_Homo sapiens_hsa002300.87187195
79ABC transporters_Homo sapiens_hsa020100.86229497
80cGMP-PKG signaling pathway_Homo sapiens_hsa040220.84869538
81Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.84569733
82Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.84191690
83Rheumatoid arthritis_Homo sapiens_hsa053230.83211533
84Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.82435297
85Gap junction_Homo sapiens_hsa045400.82404242
86Regulation of autophagy_Homo sapiens_hsa041400.81995891
87Chemical carcinogenesis_Homo sapiens_hsa052040.81187719
88Fatty acid elongation_Homo sapiens_hsa000620.80846623
89Steroid hormone biosynthesis_Homo sapiens_hsa001400.80544422
90ErbB signaling pathway_Homo sapiens_hsa040120.79979096
91Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.79918818
92Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.79513751
93Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.79407690
94Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.79109407
95Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.78910903
96Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.77054852
97Neurotrophin signaling pathway_Homo sapiens_hsa047220.76688432
98Circadian rhythm_Homo sapiens_hsa047100.76165169
99Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.76085806
100Autoimmune thyroid disease_Homo sapiens_hsa053200.74483150
101Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.74241801
102Fatty acid metabolism_Homo sapiens_hsa012120.73127464
103Nucleotide excision repair_Homo sapiens_hsa034200.72938053
104GnRH signaling pathway_Homo sapiens_hsa049120.72541975
105Retinol metabolism_Homo sapiens_hsa008300.72112688
106Vascular smooth muscle contraction_Homo sapiens_hsa042700.72064554
107Alcoholism_Homo sapiens_hsa050340.71878661
108Pyrimidine metabolism_Homo sapiens_hsa002400.71214999
109Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.71026222
110MAPK signaling pathway_Homo sapiens_hsa040100.69707895
111Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.69379556
112Gastric acid secretion_Homo sapiens_hsa049710.68797763
113Arachidonic acid metabolism_Homo sapiens_hsa005900.68718848
114Metabolic pathways_Homo sapiens_hsa011000.68221924
115Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.68186839
116Inositol phosphate metabolism_Homo sapiens_hsa005620.64820474
117Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.64650770
118Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.64443539
119Jak-STAT signaling pathway_Homo sapiens_hsa046300.63033272
120NF-kappa B signaling pathway_Homo sapiens_hsa040640.62667424
121Fatty acid degradation_Homo sapiens_hsa000710.61784949
122Estrogen signaling pathway_Homo sapiens_hsa049150.60849542
123Mineral absorption_Homo sapiens_hsa049780.60616567
124Glioma_Homo sapiens_hsa052140.60285322
125Pancreatic secretion_Homo sapiens_hsa049720.60160291
126Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.59851243
127Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.59770544
128Sphingolipid signaling pathway_Homo sapiens_hsa040710.58112691
129Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.58074486
130Folate biosynthesis_Homo sapiens_hsa007900.57790543
131Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.56881214
132Phospholipase D signaling pathway_Homo sapiens_hsa040720.55387627
133Allograft rejection_Homo sapiens_hsa053300.54462646
134Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.54352915
135Phagosome_Homo sapiens_hsa041450.53897774
136Carbohydrate digestion and absorption_Homo sapiens_hsa049730.52689023
137Base excision repair_Homo sapiens_hsa034100.52445788
138Cardiac muscle contraction_Homo sapiens_hsa042600.51214284
139Measles_Homo sapiens_hsa051620.50809783
140Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.50791419
141Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.50765927
142Ether lipid metabolism_Homo sapiens_hsa005650.50478066
143Glycerolipid metabolism_Homo sapiens_hsa005610.49938076
144Choline metabolism in cancer_Homo sapiens_hsa052310.49163995
145Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.48927169
146Osteoclast differentiation_Homo sapiens_hsa043800.47552047
147Melanogenesis_Homo sapiens_hsa049160.46404350
148Prolactin signaling pathway_Homo sapiens_hsa049170.45244112
149Ovarian steroidogenesis_Homo sapiens_hsa049130.45127030
150Cysteine and methionine metabolism_Homo sapiens_hsa002700.45092030
151Epstein-Barr virus infection_Homo sapiens_hsa051690.44562894
152Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.44497832
153Transcriptional misregulation in cancer_Homo sapiens_hsa052020.43835415
154Ras signaling pathway_Homo sapiens_hsa040140.43795123
155Hepatitis B_Homo sapiens_hsa051610.43678802
156Dorso-ventral axis formation_Homo sapiens_hsa043200.43560943
157N-Glycan biosynthesis_Homo sapiens_hsa005100.43067971
158Graft-versus-host disease_Homo sapiens_hsa053320.42974665
159Glutathione metabolism_Homo sapiens_hsa004800.41820763
160Oocyte meiosis_Homo sapiens_hsa041140.41418994
161Pentose and glucuronate interconversions_Homo sapiens_hsa000400.38447946
162RNA transport_Homo sapiens_hsa030130.38050153

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