SLC25A5P1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA deamination (GO:0045006)6.17706385
2proteasome assembly (GO:0043248)5.28615428
3negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)4.63211446
4regulation of cellular amino acid metabolic process (GO:0006521)4.61437873
5mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.55380390
6energy coupled proton transport, down electrochemical gradient (GO:0015985)4.30906051
7ATP synthesis coupled proton transport (GO:0015986)4.30906051
8positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)4.29901522
9regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450914.29478207
10DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:004.27931171
11cytidine catabolic process (GO:0006216)4.26090772
12cytidine deamination (GO:0009972)4.26090772
13cytidine metabolic process (GO:0046087)4.26090772
14signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)4.19679607
15signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)4.19679607
16signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)4.19679607
17regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)4.18333826
18intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)4.16368139
19signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)4.16368139
20negative regulation of ligase activity (GO:0051352)4.15105769
21negative regulation of ubiquitin-protein transferase activity (GO:0051444)4.15105769
22protein neddylation (GO:0045116)4.09174905
23water-soluble vitamin biosynthetic process (GO:0042364)3.98536056
24signal transduction involved in DNA integrity checkpoint (GO:0072401)3.96772948
25signal transduction involved in DNA damage checkpoint (GO:0072422)3.96772948
26rRNA modification (GO:0000154)3.94891350
27respiratory chain complex IV assembly (GO:0008535)3.90722536
28signal transduction involved in cell cycle checkpoint (GO:0072395)3.89263699
29protein deneddylation (GO:0000338)3.81063467
30cullin deneddylation (GO:0010388)3.77238972
31antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.72431418
32anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.72133513
33nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.69289847
34mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.68028324
35exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.61209876
36positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.59343164
37antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.56867734
38pyrimidine ribonucleoside catabolic process (GO:0046133)3.53107524
39cytochrome complex assembly (GO:0017004)3.50763172
40positive regulation of ligase activity (GO:0051351)3.45471420
41establishment of protein localization to mitochondrial membrane (GO:0090151)3.43879106
42respiratory electron transport chain (GO:0022904)3.40202785
43protein complex biogenesis (GO:0070271)3.39706009
44rRNA methylation (GO:0031167)3.37676483
45electron transport chain (GO:0022900)3.36841156
46DNA catabolic process, exonucleolytic (GO:0000738)3.36716315
47DNA double-strand break processing (GO:0000729)3.32995187
48regulation of cellular amine metabolic process (GO:0033238)3.32088161
49platelet dense granule organization (GO:0060155)3.31406776
50positive regulation of cell cycle arrest (GO:0071158)3.22559410
51ribosome assembly (GO:0042255)3.21875366
52RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.20835745
53RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.19893884
54tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.19893884
55mitochondrial respiratory chain complex assembly (GO:0033108)3.18990008
56aldehyde catabolic process (GO:0046185)3.15747607
57DNA damage response, signal transduction by p53 class mediator (GO:0030330)3.15250911
58transcription elongation from RNA polymerase III promoter (GO:0006385)3.14201297
59termination of RNA polymerase III transcription (GO:0006386)3.14201297
60antigen processing and presentation of peptide antigen via MHC class I (GO:0002474)3.07131300
61regulation of ubiquitin-protein transferase activity (GO:0051438)3.05722266
62chaperone-mediated protein transport (GO:0072321)3.03324837
63regulation of ligase activity (GO:0051340)2.96430452
64mannosylation (GO:0097502)2.93590138
65somatic diversification of immunoglobulins involved in immune response (GO:0002208)2.91203807
66isotype switching (GO:0045190)2.91203807
67somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)2.91203807
68negative regulation of protein ubiquitination (GO:0031397)2.88311176
69mitochondrial respiratory chain complex I assembly (GO:0032981)2.87378616
70NADH dehydrogenase complex assembly (GO:0010257)2.87378616
71mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.87378616
72negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)2.82763418
73purine deoxyribonucleoside triphosphate metabolic process (GO:0009215)2.82727633
74regulation of mitotic spindle checkpoint (GO:1903504)2.81306191
75regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.81306191
76positive regulation of inflammatory response to antigenic stimulus (GO:0002863)2.76048284
77deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.75381248
78oxidative phosphorylation (GO:0006119)2.70735446
79GPI anchor biosynthetic process (GO:0006506)2.68765590
80response to interferon-beta (GO:0035456)2.68450677
81regulation of cell cycle arrest (GO:0071156)2.67887629
82negative regulation of protein modification by small protein conjugation or removal (GO:1903321)2.66237687
83B cell mediated immunity (GO:0019724)2.65854899
84kynurenine metabolic process (GO:0070189)2.65020480
85negative regulation of G1/S transition of mitotic cell cycle (GO:2000134)2.61445599
86negative regulation of cell cycle G1/S phase transition (GO:1902807)2.61445599
87signal transduction in response to DNA damage (GO:0042770)2.60557976
88purine deoxyribonucleotide catabolic process (GO:0009155)2.58946633
89pseudouridine synthesis (GO:0001522)2.53693802
90indole-containing compound catabolic process (GO:0042436)2.52837664
91indolalkylamine catabolic process (GO:0046218)2.52837664
92tryptophan catabolic process (GO:0006569)2.52837664
93response to pheromone (GO:0019236)2.52528937
94preassembly of GPI anchor in ER membrane (GO:0016254)2.51453829
95tryptophan metabolic process (GO:0006568)2.51140361
96ATP biosynthetic process (GO:0006754)2.50972500
97AMP metabolic process (GO:0046033)2.50931875
98cellular ketone body metabolic process (GO:0046950)2.50059422
99GPI anchor metabolic process (GO:0006505)2.49841044
100purine nucleoside triphosphate biosynthetic process (GO:0009145)2.49791455

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.88722737
2GABP_17652178_ChIP-ChIP_JURKAT_Human4.21488254
3EST1_17652178_ChIP-ChIP_JURKAT_Human3.73519781
4BP1_19119308_ChIP-ChIP_Hs578T_Human3.24899820
5NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.13917978
6SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.12619634
7E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.95738989
8JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.94662070
9ELF1_17652178_ChIP-ChIP_JURKAT_Human2.93340517
10HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.69123135
11VDR_22108803_ChIP-Seq_LS180_Human2.68607404
12VDR_23849224_ChIP-Seq_CD4+_Human2.66777783
13FLI1_27457419_Chip-Seq_LIVER_Mouse2.44859290
14MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.43606740
15ETS1_20019798_ChIP-Seq_JURKAT_Human2.37313616
16ELK1_19687146_ChIP-ChIP_HELA_Human2.34319790
17CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.18732714
18CREB1_15753290_ChIP-ChIP_HEK293T_Human2.17053441
19FOXP3_21729870_ChIP-Seq_TREG_Human2.15661387
20SRF_21415370_ChIP-Seq_HL-1_Mouse2.08784871
21FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.03640683
22IRF8_22096565_ChIP-ChIP_GC-B_Human1.98495770
23IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.95257160
24E2F4_17652178_ChIP-ChIP_JURKAT_Human1.91161846
25PCGF2_27294783_Chip-Seq_ESCs_Mouse1.89270865
26E2F7_22180533_ChIP-Seq_HELA_Human1.82338890
27ZNF274_21170338_ChIP-Seq_K562_Hela1.80279413
28MYC_18555785_ChIP-Seq_MESCs_Mouse1.69579276
29CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.68940274
30IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.64174482
31FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.59973129
32HOXB4_20404135_ChIP-ChIP_EML_Mouse1.59274526
33CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.58649122
34PADI4_21655091_ChIP-ChIP_MCF-7_Human1.57757257
35PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.57428691
36PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.56199319
37IRF8_21731497_ChIP-ChIP_J774_Mouse1.50943290
38MYC_18358816_ChIP-ChIP_MESCs_Mouse1.47731178
39EWS_26573619_Chip-Seq_HEK293_Human1.43970324
40PCGF2_27294783_Chip-Seq_NPCs_Mouse1.39655440
41IGF1R_20145208_ChIP-Seq_DFB_Human1.38548567
42MYC_18940864_ChIP-ChIP_HL60_Human1.37529100
43EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.37000461
44E2F1_18555785_ChIP-Seq_MESCs_Mouse1.36319151
45EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.35010178
46FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.34356128
47DCP1A_22483619_ChIP-Seq_HELA_Human1.33219192
48FOXA1_27270436_Chip-Seq_PROSTATE_Human1.32999118
49FOXA1_25329375_ChIP-Seq_VCAP_Human1.32999118
50MYC_19030024_ChIP-ChIP_MESCs_Mouse1.32629261
51GATA3_26560356_Chip-Seq_TH2_Human1.30888126
52SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.28856465
53POU3F2_20337985_ChIP-ChIP_501MEL_Human1.23719671
54HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.23405237
55NOTCH1_21737748_ChIP-Seq_TLL_Human1.22888960
56TAF15_26573619_Chip-Seq_HEK293_Human1.22626341
57FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.22624666
58CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.21876179
59FUS_26573619_Chip-Seq_HEK293_Human1.21404740
60GABP_19822575_ChIP-Seq_HepG2_Human1.20275712
61AR_20517297_ChIP-Seq_VCAP_Human1.20193504
62SOX2_19829295_ChIP-Seq_ESCs_Human1.19666162
63NANOG_19829295_ChIP-Seq_ESCs_Human1.19666162
64NFE2_27457419_Chip-Seq_LIVER_Mouse1.19594578
65P300_19829295_ChIP-Seq_ESCs_Human1.18950761
66SUZ12_27294783_Chip-Seq_NPCs_Mouse1.16029051
67MYB_26560356_Chip-Seq_TH2_Human1.14627928
68GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.12961935
69GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.11844937
70TP53_22573176_ChIP-Seq_HFKS_Human1.11580586
71YY1_21170310_ChIP-Seq_MESCs_Mouse1.10738449
72POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.07887120
73FOXA1_21572438_ChIP-Seq_LNCaP_Human1.07676980
74ELK1_22589737_ChIP-Seq_MCF10A_Human1.06823571
75SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.06305700
76EGR1_23403033_ChIP-Seq_LIVER_Mouse1.05067417
77CTBP1_25329375_ChIP-Seq_LNCAP_Human1.05009051
78CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.04534593
79TTF2_22483619_ChIP-Seq_HELA_Human1.03504461
80EZH2_27294783_Chip-Seq_NPCs_Mouse1.03363411
81ZFP57_27257070_Chip-Seq_ESCs_Mouse1.03208893
82HTT_18923047_ChIP-ChIP_STHdh_Human1.01444327
83ER_23166858_ChIP-Seq_MCF-7_Human1.01135051
84PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.00596932
85FOXH1_21741376_ChIP-Seq_EPCs_Human0.98261325
86NCOR_22424771_ChIP-Seq_293T_Human0.96774667
87EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.96152114
88IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.94785833
89CBP_20019798_ChIP-Seq_JUKART_Human0.94785833
90AUTS2_25519132_ChIP-Seq_293T-REX_Human0.93951255
91ERG_20517297_ChIP-Seq_VCAP_Human0.93505764
92PBX1_22567123_ChIP-ChIP_OVCAR3_Human0.93270972
93ZFP42_18358816_ChIP-ChIP_MESCs_Mouse0.93213441
94SALL4_22934838_ChIP-ChIP_CD34+_Human0.90771478
95IRF1_19129219_ChIP-ChIP_H3396_Human0.88878215
96TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.88487513
97CRX_20693478_ChIP-Seq_RETINA_Mouse0.88304758
98SPI1_23547873_ChIP-Seq_NB4_Human0.87906367
99RBPJ_21746931_ChIP-Seq_IB4_Human0.87893140
100NANOG_20526341_ChIP-Seq_ESCs_Human0.87448222

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005671_abnormal_response_to3.64222008
2MP0001835_abnormal_antigen_presentation3.46073422
3MP0003806_abnormal_nucleotide_metabolis2.88979853
4MP0008058_abnormal_DNA_repair2.86829365
5MP0002102_abnormal_ear_morphology2.78918529
6MP0004147_increased_porphyrin_level2.78677171
7MP0003195_calcinosis2.71479905
8MP0002166_altered_tumor_susceptibility2.43888230
9MP0009785_altered_susceptibility_to2.43232705
10MP0006072_abnormal_retinal_apoptosis2.32687106
11MP0008875_abnormal_xenobiotic_pharmacok2.30474827
12MP0003786_premature_aging2.22428510
13MP0002006_tumorigenesis2.22119990
14MP0005084_abnormal_gallbladder_morpholo2.19827031
15MP0008877_abnormal_DNA_methylation2.17916467
16MP0006036_abnormal_mitochondrial_physio2.08619607
17MP0010094_abnormal_chromosome_stability2.08540340
18MP0009333_abnormal_splenocyte_physiolog2.04250811
19MP0002148_abnormal_hypersensitivity_rea1.98478952
20MP0008872_abnormal_physiological_respon1.96912790
21MP0009697_abnormal_copulation1.83273908
22MP0005410_abnormal_fertilization1.82800871
23MP0005645_abnormal_hypothalamus_physiol1.80592823
24MP0000685_abnormal_immune_system1.70671199
25MP0001873_stomach_inflammation1.68473732
26MP0005075_abnormal_melanosome_morpholog1.64040792
27MP0003878_abnormal_ear_physiology1.62510219
28MP0005377_hearing/vestibular/ear_phenot1.62510219
29MP0003718_maternal_effect1.60908748
30MP0002138_abnormal_hepatobiliary_system1.59123592
31MP0001800_abnormal_humoral_immune1.55898377
32MP0005000_abnormal_immune_tolerance1.52395999
33MP0002837_dystrophic_cardiac_calcinosis1.47841347
34MP0008007_abnormal_cellular_replicative1.47173112
35MP0004957_abnormal_blastocyst_morpholog1.43004281
36MP0003693_abnormal_embryo_hatching1.42980230
37MP0001790_abnormal_immune_system1.40247134
38MP0005387_immune_system_phenotype1.40247134
39MP0000372_irregular_coat_pigmentation1.38918201
40MP0003186_abnormal_redox_activity1.38157625
41MP0009764_decreased_sensitivity_to1.28834841
42MP0005379_endocrine/exocrine_gland_phen1.26928388
43MP0003866_abnormal_defecation1.26093579
44MP0006035_abnormal_mitochondrial_morpho1.25693749
45MP0005636_abnormal_mineral_homeostasis1.24531607
46MP0005551_abnormal_eye_electrophysiolog1.23851829
47MP0002736_abnormal_nociception_after1.23835321
48MP0003011_delayed_dark_adaptation1.23781011
49MP0003763_abnormal_thymus_physiology1.23589018
50MP0002723_abnormal_immune_serum1.23080547
51MP0002452_abnormal_antigen_presenting1.21905120
52MP0002420_abnormal_adaptive_immunity1.21140496
53MP0005367_renal/urinary_system_phenotyp1.19567050
54MP0000516_abnormal_urinary_system1.19567050
55MP0006054_spinal_hemorrhage1.19259504
56MP0001905_abnormal_dopamine_level1.18918845
57MP0001819_abnormal_immune_cell1.18682034
58MP0006082_CNS_inflammation1.16157409
59MP0003252_abnormal_bile_duct1.15031078
60MP0001968_abnormal_touch/_nociception1.14819489
61MP0005332_abnormal_amino_acid1.13492353
62MP0005253_abnormal_eye_physiology1.12656188
63MP0002693_abnormal_pancreas_physiology1.08753533
64MP0003646_muscle_fatigue1.03427444
65MP0005025_abnormal_response_to1.00560225
66MP0002277_abnormal_respiratory_mucosa1.00342204
67MP0000689_abnormal_spleen_morphology0.98646258
68MP0001845_abnormal_inflammatory_respons0.97904654
69MP0004145_abnormal_muscle_electrophysio0.97866410
70MP0001501_abnormal_sleep_pattern0.97774888
71MP0002876_abnormal_thyroid_physiology0.97073822
72MP0002398_abnormal_bone_marrow0.93425207
73MP0001764_abnormal_homeostasis0.91849020
74MP0004215_abnormal_myocardial_fiber0.91433567
75MP0010155_abnormal_intestine_physiology0.91148801
76MP0008775_abnormal_heart_ventricle0.90713684
77MP0001929_abnormal_gametogenesis0.90271023
78MP0008469_abnormal_protein_level0.88249204
79MP0008873_increased_physiological_sensi0.87153450
80MP0001984_abnormal_olfaction0.87091022
81MP0000716_abnormal_immune_system0.86771070
82MP0005085_abnormal_gallbladder_physiolo0.86359909
83MP0001765_abnormal_ion_homeostasis0.86253986
84MP0001986_abnormal_taste_sensitivity0.84477784
85MP0008995_early_reproductive_senescence0.80242917
86MP0008057_abnormal_DNA_replication0.79399150
87MP0001853_heart_inflammation0.78879563
88MP0002019_abnormal_tumor_incidence0.78417634
89MP0005319_abnormal_enzyme/_coenzyme0.78108597
90MP0005389_reproductive_system_phenotype0.77605855
91MP0002419_abnormal_innate_immunity0.77039740
92MP0001485_abnormal_pinna_reflex0.76484986
93MP0002405_respiratory_system_inflammati0.76075384
94MP0002429_abnormal_blood_cell0.75482962
95MP0003111_abnormal_nucleus_morphology0.75354705
96MP0009643_abnormal_urine_homeostasis0.75069032
97MP0001529_abnormal_vocalization0.74687912
98MP0002254_reproductive_system_inflammat0.73861209
99MP0002722_abnormal_immune_system0.73266231
100MP0003077_abnormal_cell_cycle0.72798864

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)4.25442196
2Mitochondrial inheritance (HP:0001427)4.25148810
3Increased CSF lactate (HP:0002490)4.14133046
4Hepatocellular necrosis (HP:0001404)3.93062316
5Increased hepatocellular lipid droplets (HP:0006565)3.82302392
6Abnormal mitochondria in muscle tissue (HP:0008316)3.78347337
7Hepatic necrosis (HP:0002605)3.77089839
8Progressive macrocephaly (HP:0004481)3.71047065
9Acute encephalopathy (HP:0006846)3.69868884
10Aplastic anemia (HP:0001915)3.44298185
11Lipid accumulation in hepatocytes (HP:0006561)3.38369161
12Renal Fanconi syndrome (HP:0001994)3.26851352
13Increased serum lactate (HP:0002151)3.09305904
14Cerebral edema (HP:0002181)3.06119478
15Methylmalonic acidemia (HP:0002912)3.01689447
16Hypothermia (HP:0002045)2.95901837
17Exertional dyspnea (HP:0002875)2.95739327
18Hypoproteinemia (HP:0003075)2.94091292
19IgG deficiency (HP:0004315)2.92368790
20Elevated erythrocyte sedimentation rate (HP:0003565)2.84224761
21Lactic acidosis (HP:0003128)2.77083829
22Abolished electroretinogram (ERG) (HP:0000550)2.75315924
233-Methylglutaconic aciduria (HP:0003535)2.72024842
24Increased intramyocellular lipid droplets (HP:0012240)2.71087132
25Type I transferrin isoform profile (HP:0003642)2.64589232
26Decreased activity of mitochondrial respiratory chain (HP:0008972)2.63754492
27Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.63754492
28Methylmalonic aciduria (HP:0012120)2.55522183
29Glycosuria (HP:0003076)2.53924961
30Abnormality of urine glucose concentration (HP:0011016)2.53924961
31Abnormality of the prostate (HP:0008775)2.52109948
32Generalized aminoaciduria (HP:0002909)2.50575347
33Abnormality of aspartate family amino acid metabolism (HP:0010899)2.50431860
34Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.50119676
35Congenital, generalized hypertrichosis (HP:0004540)2.49312217
36Respiratory failure (HP:0002878)2.42969949
37IgM deficiency (HP:0002850)2.41687294
38Optic disc pallor (HP:0000543)2.35834209
39Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.33001920
40Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.32817160
41Abnormality of alanine metabolism (HP:0010916)2.32817160
42Hyperalaninemia (HP:0003348)2.32817160
43Palpitations (HP:0001962)2.32548682
44Stomatitis (HP:0010280)2.29739479
45Pancreatic cysts (HP:0001737)2.29262704
46Lethargy (HP:0001254)2.28025966
47Severe combined immunodeficiency (HP:0004430)2.23380110
48Abnormality of vitamin B metabolism (HP:0004340)2.21301915
49Pancytopenia (HP:0001876)2.16512047
50T lymphocytopenia (HP:0005403)2.14474506
51Abnormality of T cell number (HP:0011839)2.13886489
52Attenuation of retinal blood vessels (HP:0007843)2.13304743
53Exercise intolerance (HP:0003546)2.13180051
54Abnormal protein glycosylation (HP:0012346)2.12806001
55Abnormal glycosylation (HP:0012345)2.12806001
56Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.12806001
57Abnormal protein N-linked glycosylation (HP:0012347)2.12806001
58Increased serum pyruvate (HP:0003542)2.12426875
59Increased muscle lipid content (HP:0009058)2.11411613
60Abnormal spermatogenesis (HP:0008669)2.10901236
61Abnormality of methionine metabolism (HP:0010901)2.09384138
62Abnormality of serum amino acid levels (HP:0003112)2.07589227
63Abnormality of the vitamin B12 metabolism (HP:0004341)2.07161945
64Thyroiditis (HP:0100646)2.06549293
65Congenital stationary night blindness (HP:0007642)2.05922363
66Decreased electroretinogram (ERG) amplitude (HP:0000654)2.03842196
67Abnormality of renal resorption (HP:0011038)2.01861099
68Cerebral palsy (HP:0100021)2.00112537
69Type 2 muscle fiber atrophy (HP:0003554)1.99689487
70Abnormality of T cells (HP:0002843)1.99405805
71Abnormality of midbrain morphology (HP:0002418)1.95203624
72Molar tooth sign on MRI (HP:0002419)1.95203624
73Colon cancer (HP:0003003)1.94830709
74Abnormality of dicarboxylic acid metabolism (HP:0010995)1.87684624
75Dicarboxylic aciduria (HP:0003215)1.87684624
76Abnormality of B cell number (HP:0010975)1.87053709
77CNS demyelination (HP:0007305)1.86388061
78Nausea (HP:0002018)1.84559365
79Posterior subcapsular cataract (HP:0007787)1.84397093
80Leukodystrophy (HP:0002415)1.82960386
81Hyperphosphaturia (HP:0003109)1.82022592
82Nephronophthisis (HP:0000090)1.81399258
83Abnormality of glycolysis (HP:0004366)1.81125852
84Hypoalbuminemia (HP:0003073)1.80680239
85Abnormal albumin level (HP:0012116)1.80680239
86Autoimmune hemolytic anemia (HP:0001890)1.78555176
87Neoplasm of the adrenal gland (HP:0100631)1.77928800
88Tongue fasciculations (HP:0001308)1.77895794
89Combined immunodeficiency (HP:0005387)1.77570555
90Hypomagnesemia (HP:0002917)1.77255332
91Reduced antithrombin III activity (HP:0001976)1.76217998
92Respiratory difficulties (HP:0002880)1.75282556
93Azoospermia (HP:0000027)1.75212529
94Abnormality of the labia minora (HP:0012880)1.72346958
95Constricted visual fields (HP:0001133)1.71416232
96Abnormality of T cell physiology (HP:0011840)1.70190195
97Abnormal rod and cone electroretinograms (HP:0008323)1.67371247
98Hypoglycemic coma (HP:0001325)1.67296111
99Abnormality of the renal cortex (HP:0011035)1.67114074
100Pancreatic fibrosis (HP:0100732)1.66258001

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MST43.05655010
2EIF2AK33.03255656
3VRK22.98961761
4TSSK62.71113408
5TXK2.68363211
6NUAK12.64597653
7ZAK2.57155105
8BUB12.52706770
9MAP3K122.46255835
10KDR2.24653995
11FRK2.18070431
12TLK12.09117015
13TRIM282.02262398
14MAP4K21.94865325
15PLK41.82522172
16VRK11.81209546
17GRK11.79929702
18BMPR1B1.78409773
19BCKDK1.70815956
20EIF2AK11.70187227
21STK161.69014853
22TIE11.65869392
23ADRBK21.60757177
24PLK31.60126901
25MKNK21.58725223
26NEK11.51565946
27TAOK31.51025284
28ERBB31.50730857
29WNK31.43492310
30DAPK11.37345981
31TEC1.37020182
32MKNK11.36394896
33SRPK11.36311094
34PASK1.23564193
35MYLK1.22665140
36ACVR1B1.19001912
37OXSR11.18196230
38ITK1.15743075
39TESK21.12634327
40BMPR21.11546039
41SCYL21.09296586
42NME11.08229120
43CSNK1G31.04406006
44INSRR1.02841654
45TAF11.00718557
46EIF2AK20.98984439
47PLK20.94400494
48TESK10.92915844
49PBK0.89702589
50CSNK1G10.88906101
51TNIK0.87699871
52WNK40.84900774
53CSNK1G20.83357785
54MAP4K10.82645829
55MAP2K60.81702475
56STK390.77430980
57FES0.73191165
58PHKG20.72475525
59PHKG10.72475525
60CSNK1A1L0.72244309
61MAPKAPK30.71848418
62SYK0.67697538
63KIT0.66135994
64ALK0.65448429
65LIMK10.63586970
66BCR0.62893144
67PLK10.62886922
68IKBKB0.62274106
69TGFBR10.59242867
70STK38L0.58179571
71CDK190.56710883
72TTK0.55163247
73PRKCQ0.55158205
74PINK10.51984646
75CDK80.50286581
76CDC70.49910428
77PDK20.49239669
78PRKCE0.47927020
79ATR0.47429071
80FLT30.47122993
81ILK0.46302966
82LCK0.45396168
83LYN0.45080601
84GRK70.43936281
85GRK50.43050926
86PIK3CG0.43017980
87BRSK20.42019846
88PAK40.41574881
89RPS6KA50.40680690
90MAP3K140.40128795
91BTK0.39267718
92ADRBK10.38832703
93IGF1R0.37887079
94CSNK2A10.37262401
95WEE10.37019451
96DAPK20.36591157
97AURKB0.34465297
98ABL10.32946953
99MAPK130.32690466
100MAPKAPK50.32511488

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030505.36220934
2Asthma_Homo sapiens_hsa053102.99415273
3Protein export_Homo sapiens_hsa030602.97981910
4Oxidative phosphorylation_Homo sapiens_hsa001902.91915979
5Parkinsons disease_Homo sapiens_hsa050122.54955478
6Allograft rejection_Homo sapiens_hsa053302.52902351
7Type I diabetes mellitus_Homo sapiens_hsa049402.40728475
8Autoimmune thyroid disease_Homo sapiens_hsa053202.37190570
9RNA polymerase_Homo sapiens_hsa030202.28146934
10Graft-versus-host disease_Homo sapiens_hsa053322.16549738
11Intestinal immune network for IgA production_Homo sapiens_hsa046722.06296035
12Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.97821787
13Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.81403895
14One carbon pool by folate_Homo sapiens_hsa006701.76155680
15Mismatch repair_Homo sapiens_hsa034301.72126283
16Antigen processing and presentation_Homo sapiens_hsa046121.71612983
17Primary immunodeficiency_Homo sapiens_hsa053401.67323051
18Homologous recombination_Homo sapiens_hsa034401.66345353
19Propanoate metabolism_Homo sapiens_hsa006401.64551030
20Caffeine metabolism_Homo sapiens_hsa002321.60121798
21Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.56654105
22Huntingtons disease_Homo sapiens_hsa050161.55123511
23Alzheimers disease_Homo sapiens_hsa050101.51945313
24DNA replication_Homo sapiens_hsa030301.49807113
25Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.47561520
26Non-homologous end-joining_Homo sapiens_hsa034501.39323504
27Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.38186604
28RNA degradation_Homo sapiens_hsa030181.37925773
29Rheumatoid arthritis_Homo sapiens_hsa053231.27839691
30Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.26417212
31Sulfur metabolism_Homo sapiens_hsa009201.25983786
32Fatty acid elongation_Homo sapiens_hsa000621.25943449
33Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.23859764
34Basal transcription factors_Homo sapiens_hsa030221.19578173
35Ribosome_Homo sapiens_hsa030101.17833587
36Pyrimidine metabolism_Homo sapiens_hsa002401.14413410
37Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.12738310
38RNA transport_Homo sapiens_hsa030131.11316691
39Base excision repair_Homo sapiens_hsa034101.08348232
40Purine metabolism_Homo sapiens_hsa002301.04303364
41Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.03890483
42Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.03351818
43Butanoate metabolism_Homo sapiens_hsa006501.01080868
44Tryptophan metabolism_Homo sapiens_hsa003800.97329224
45Cysteine and methionine metabolism_Homo sapiens_hsa002700.95630159
46Hematopoietic cell lineage_Homo sapiens_hsa046400.92192875
47Phototransduction_Homo sapiens_hsa047440.91847126
48Nucleotide excision repair_Homo sapiens_hsa034200.91158160
49Viral myocarditis_Homo sapiens_hsa054160.90773714
50Fanconi anemia pathway_Homo sapiens_hsa034600.90343766
51Peroxisome_Homo sapiens_hsa041460.89886480
522-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.85663786
53Pyruvate metabolism_Homo sapiens_hsa006200.84835584
54Spliceosome_Homo sapiens_hsa030400.80870931
55Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.79313095
56Maturity onset diabetes of the young_Homo sapiens_hsa049500.78835033
57Cardiac muscle contraction_Homo sapiens_hsa042600.78616329
58Vitamin B6 metabolism_Homo sapiens_hsa007500.78343023
59Nitrogen metabolism_Homo sapiens_hsa009100.77438069
60Selenocompound metabolism_Homo sapiens_hsa004500.75007440
61Glutathione metabolism_Homo sapiens_hsa004800.69060262
62Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.68532591
63Pentose and glucuronate interconversions_Homo sapiens_hsa000400.67729599
64Linoleic acid metabolism_Homo sapiens_hsa005910.67405029
65Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.67031802
66Regulation of autophagy_Homo sapiens_hsa041400.65277402
67Drug metabolism - other enzymes_Homo sapiens_hsa009830.63850057
68Metabolic pathways_Homo sapiens_hsa011000.62863882
69Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.61916070
70Chemical carcinogenesis_Homo sapiens_hsa052040.61815735
71Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.61368785
72SNARE interactions in vesicular transport_Homo sapiens_hsa041300.59589375
73Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.57741188
74Carbon metabolism_Homo sapiens_hsa012000.52869589
75Collecting duct acid secretion_Homo sapiens_hsa049660.52024278
76Systemic lupus erythematosus_Homo sapiens_hsa053220.50345245
77Staphylococcus aureus infection_Homo sapiens_hsa051500.49290671
78Fatty acid degradation_Homo sapiens_hsa000710.49257837
79Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.48736394
80Arachidonic acid metabolism_Homo sapiens_hsa005900.47873863
81Primary bile acid biosynthesis_Homo sapiens_hsa001200.47855277
82Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.47796942
83Legionellosis_Homo sapiens_hsa051340.47107790
84Retinol metabolism_Homo sapiens_hsa008300.47105999
85Fatty acid metabolism_Homo sapiens_hsa012120.44522230
86Folate biosynthesis_Homo sapiens_hsa007900.43958181
87Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.43423427
88Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.43299522
89alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.43128526
90Epstein-Barr virus infection_Homo sapiens_hsa051690.42105903
91Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.41827420
92Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.40762728
93Steroid biosynthesis_Homo sapiens_hsa001000.38418589
94Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.37953233
95Ether lipid metabolism_Homo sapiens_hsa005650.37854516
96Herpes simplex infection_Homo sapiens_hsa051680.37545583
97Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.33365959
98Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.31740816
99beta-Alanine metabolism_Homo sapiens_hsa004100.30686259
100Steroid hormone biosynthesis_Homo sapiens_hsa001400.28458017

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »