

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 6.83221878 |
| 2 | proteasome assembly (GO:0043248) | 6.01540530 |
| 3 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.72275092 |
| 4 | ATP synthesis coupled proton transport (GO:0015986) | 4.70926873 |
| 5 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.70926873 |
| 6 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.58333714 |
| 7 | regulation of cellular amino acid metabolic process (GO:0006521) | 4.44833606 |
| 8 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 4.42573491 |
| 9 | leukotriene biosynthetic process (GO:0019370) | 4.42315953 |
| 10 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 4.40152933 |
| 11 | rRNA modification (GO:0000154) | 4.38853608 |
| 12 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 4.28507300 |
| 13 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 4.28507300 |
| 14 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 4.24839894 |
| 15 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 4.24839894 |
| 16 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 4.24839894 |
| 17 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 4.22772984 |
| 18 | protein neddylation (GO:0045116) | 4.05073400 |
| 19 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 4.04770190 |
| 20 | negative regulation of ligase activity (GO:0051352) | 4.04770190 |
| 21 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 4.04667378 |
| 22 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 4.04667378 |
| 23 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.98480373 |
| 24 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.97012752 |
| 25 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.94376026 |
| 26 | cullin deneddylation (GO:0010388) | 3.93501749 |
| 27 | viral mRNA export from host cell nucleus (GO:0046784) | 3.86593564 |
| 28 | protein K6-linked ubiquitination (GO:0085020) | 3.86546127 |
| 29 | protein deneddylation (GO:0000338) | 3.83038721 |
| 30 | rRNA methylation (GO:0031167) | 3.81213268 |
| 31 | protein complex biogenesis (GO:0070271) | 3.80690791 |
| 32 | negative regulation of thymocyte apoptotic process (GO:0070244) | 3.74543093 |
| 33 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.73934048 |
| 34 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.72140170 |
| 35 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.71808465 |
| 36 | histamine secretion (GO:0001821) | 3.70285719 |
| 37 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.69611231 |
| 38 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.61383528 |
| 39 | NADH dehydrogenase complex assembly (GO:0010257) | 3.61383528 |
| 40 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.61383528 |
| 41 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.61371381 |
| 42 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.57873720 |
| 43 | GTP biosynthetic process (GO:0006183) | 3.55729522 |
| 44 | positive regulation of ligase activity (GO:0051351) | 3.55599470 |
| 45 | chaperone-mediated protein transport (GO:0072321) | 3.54430750 |
| 46 | platelet dense granule organization (GO:0060155) | 3.51618847 |
| 47 | DNA double-strand break processing (GO:0000729) | 3.48867187 |
| 48 | respiratory chain complex IV assembly (GO:0008535) | 3.44694312 |
| 49 | respiratory electron transport chain (GO:0022904) | 3.42570778 |
| 50 | electron transport chain (GO:0022900) | 3.38357144 |
| 51 | regulation of cellular amine metabolic process (GO:0033238) | 3.34794783 |
| 52 | cytidine catabolic process (GO:0006216) | 3.28011612 |
| 53 | cytidine deamination (GO:0009972) | 3.28011612 |
| 54 | cytidine metabolic process (GO:0046087) | 3.28011612 |
| 55 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.24564325 |
| 56 | activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c (GO | 3.24527067 |
| 57 | positive regulation of cell cycle arrest (GO:0071158) | 3.22215908 |
| 58 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.20648320 |
| 59 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 3.15416817 |
| 60 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.12470909 |
| 61 | cytochrome complex assembly (GO:0017004) | 3.12412142 |
| 62 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 3.10987966 |
| 63 | ribosome assembly (GO:0042255) | 3.10690324 |
| 64 | purine deoxyribonucleoside triphosphate metabolic process (GO:0009215) | 3.10333989 |
| 65 | response to pheromone (GO:0019236) | 3.04497794 |
| 66 | regulation of ligase activity (GO:0051340) | 2.99778221 |
| 67 | histamine transport (GO:0051608) | 2.98985310 |
| 68 | pseudouridine synthesis (GO:0001522) | 2.97104921 |
| 69 | UTP biosynthetic process (GO:0006228) | 2.93266416 |
| 70 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.92451099 |
| 71 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 2.91639630 |
| 72 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 2.91029633 |
| 73 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 2.90518844 |
| 74 | regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003339 | 2.88855646 |
| 75 | dopamine transport (GO:0015872) | 2.87010904 |
| 76 | adenosine metabolic process (GO:0046085) | 2.86491951 |
| 77 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 2.83724248 |
| 78 | negative regulation of cell cycle G1/S phase transition (GO:1902807) | 2.80966280 |
| 79 | negative regulation of G1/S transition of mitotic cell cycle (GO:2000134) | 2.80966280 |
| 80 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.74852057 |
| 81 | termination of RNA polymerase III transcription (GO:0006386) | 2.74852057 |
| 82 | negative regulation of protein ubiquitination (GO:0031397) | 2.70389617 |
| 83 | protein prenylation (GO:0018342) | 2.67956549 |
| 84 | prenylation (GO:0097354) | 2.67956549 |
| 85 | antigen processing and presentation of peptide antigen via MHC class I (GO:0002474) | 2.66655531 |
| 86 | L-fucose catabolic process (GO:0042355) | 2.66010759 |
| 87 | fucose catabolic process (GO:0019317) | 2.66010759 |
| 88 | L-fucose metabolic process (GO:0042354) | 2.66010759 |
| 89 | double-strand break repair via homologous recombination (GO:0000724) | 2.65842739 |
| 90 | regulation of cell cycle arrest (GO:0071156) | 2.65511274 |
| 91 | preassembly of GPI anchor in ER membrane (GO:0016254) | 2.64328812 |
| 92 | recombinational repair (GO:0000725) | 2.64130550 |
| 93 | regulation of B cell apoptotic process (GO:0002902) | 2.62573714 |
| 94 | ATP biosynthetic process (GO:0006754) | 2.60985741 |
| 95 | positive regulation of DNA recombination (GO:0045911) | 2.60608323 |
| 96 | fatty acid derivative biosynthetic process (GO:1901570) | 2.60400691 |
| 97 | icosanoid biosynthetic process (GO:0046456) | 2.60400691 |
| 98 | CTP biosynthetic process (GO:0006241) | 2.59345796 |
| 99 | CTP metabolic process (GO:0046036) | 2.59345796 |
| 100 | protein-cofactor linkage (GO:0018065) | 2.58646572 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.48264939 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.21774529 |
| 3 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.13938745 |
| 4 | VDR_22108803_ChIP-Seq_LS180_Human | 4.08845331 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.95318245 |
| 6 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.83755265 |
| 7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.75069140 |
| 8 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.72286812 |
| 9 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.68876330 |
| 10 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.68733959 |
| 11 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.62425739 |
| 12 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.52664129 |
| 13 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.49678345 |
| 14 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.30014303 |
| 15 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.24857863 |
| 16 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 2.22213547 |
| 17 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.21266573 |
| 18 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.20030054 |
| 19 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.02471754 |
| 20 | EWS_26573619_Chip-Seq_HEK293_Human | 1.95042021 |
| 21 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.93684614 |
| 22 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.93096005 |
| 23 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.88870095 |
| 24 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.86195521 |
| 25 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.82739658 |
| 26 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.77496813 |
| 27 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.71819035 |
| 28 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.66721236 |
| 29 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.66164255 |
| 30 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.60049761 |
| 31 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.58698218 |
| 32 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.57079127 |
| 33 | FUS_26573619_Chip-Seq_HEK293_Human | 1.56562838 |
| 34 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.56098424 |
| 35 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.46173213 |
| 36 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.44816946 |
| 37 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.44073477 |
| 38 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.43833510 |
| 39 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.42447513 |
| 40 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.41429363 |
| 41 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.41357412 |
| 42 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.40714495 |
| 43 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.40042310 |
| 44 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.37646957 |
| 45 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.37261312 |
| 46 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.34709734 |
| 47 | P300_19829295_ChIP-Seq_ESCs_Human | 1.34707389 |
| 48 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.34181800 |
| 49 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.31838284 |
| 50 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.31786723 |
| 51 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.31162901 |
| 52 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.31018298 |
| 53 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.30839527 |
| 54 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.28010724 |
| 55 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.27380661 |
| 56 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.26793413 |
| 57 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.24869602 |
| 58 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.23706830 |
| 59 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.22532556 |
| 60 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.19336026 |
| 61 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.18983118 |
| 62 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.17020204 |
| 63 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.16766294 |
| 64 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.13214269 |
| 65 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.13214269 |
| 66 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.11503917 |
| 67 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.11302764 |
| 68 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.11007601 |
| 69 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.10521594 |
| 70 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.07729206 |
| 71 | AR_20517297_ChIP-Seq_VCAP_Human | 1.05556433 |
| 72 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.02937896 |
| 73 | NCOR_22424771_ChIP-Seq_293T_Human | 1.02777935 |
| 74 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.02141746 |
| 75 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.02091126 |
| 76 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.02084526 |
| 77 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.01325517 |
| 78 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.01034355 |
| 79 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.00934659 |
| 80 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.00892272 |
| 81 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.00892272 |
| 82 | GATA3_26560356_Chip-Seq_TH2_Human | 1.00288462 |
| 83 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.99951771 |
| 84 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 0.99003803 |
| 85 | GATA3_26560356_Chip-Seq_TH1_Human | 0.98361807 |
| 86 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.97764539 |
| 87 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.97663106 |
| 88 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 0.96230378 |
| 89 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.94139684 |
| 90 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.93638003 |
| 91 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.92701290 |
| 92 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.92380051 |
| 93 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.91732875 |
| 94 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 0.91656224 |
| 95 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 0.90809287 |
| 96 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.90251650 |
| 97 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 0.90036777 |
| 98 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.89671595 |
| 99 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.89647919 |
| 100 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.89196066 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0000372_irregular_coat_pigmentation | 3.49434104 |
| 2 | MP0002736_abnormal_nociception_after | 3.41607269 |
| 3 | MP0002102_abnormal_ear_morphology | 3.06276145 |
| 4 | MP0001835_abnormal_antigen_presentation | 3.05786030 |
| 5 | MP0003195_calcinosis | 2.92706003 |
| 6 | MP0009697_abnormal_copulation | 2.89918070 |
| 7 | MP0001968_abnormal_touch/_nociception | 2.71930859 |
| 8 | MP0002163_abnormal_gland_morphology | 2.69377649 |
| 9 | MP0006036_abnormal_mitochondrial_physio | 2.38938739 |
| 10 | MP0003693_abnormal_embryo_hatching | 2.28430700 |
| 11 | MP0005075_abnormal_melanosome_morpholog | 2.28078049 |
| 12 | MP0002095_abnormal_skin_pigmentation | 2.23921288 |
| 13 | MP0005408_hypopigmentation | 2.13731871 |
| 14 | MP0003806_abnormal_nucleotide_metabolis | 2.11840914 |
| 15 | MP0005379_endocrine/exocrine_gland_phen | 2.11388889 |
| 16 | MP0005671_abnormal_response_to | 2.07353421 |
| 17 | MP0000015_abnormal_ear_pigmentation | 1.90079026 |
| 18 | MP0005377_hearing/vestibular/ear_phenot | 1.85526900 |
| 19 | MP0003878_abnormal_ear_physiology | 1.85526900 |
| 20 | MP0005171_absent_coat_pigmentation | 1.83003039 |
| 21 | MP0009333_abnormal_splenocyte_physiolog | 1.82420217 |
| 22 | MP0010094_abnormal_chromosome_stability | 1.77330630 |
| 23 | MP0008872_abnormal_physiological_respon | 1.76547552 |
| 24 | MP0003786_premature_aging | 1.74600043 |
| 25 | MP0001873_stomach_inflammation | 1.72846154 |
| 26 | MP0003252_abnormal_bile_duct | 1.72620520 |
| 27 | MP0002166_altered_tumor_susceptibility | 1.70618693 |
| 28 | MP0005551_abnormal_eye_electrophysiolog | 1.67635162 |
| 29 | MP0008058_abnormal_DNA_repair | 1.66679735 |
| 30 | MP0006035_abnormal_mitochondrial_morpho | 1.65733513 |
| 31 | MP0003646_muscle_fatigue | 1.63893230 |
| 32 | MP0003186_abnormal_redox_activity | 1.61896126 |
| 33 | MP0005084_abnormal_gallbladder_morpholo | 1.60900211 |
| 34 | MP0004147_increased_porphyrin_level | 1.59117660 |
| 35 | MP0008875_abnormal_xenobiotic_pharmacok | 1.51548060 |
| 36 | MP0000427_abnormal_hair_cycle | 1.50360657 |
| 37 | MP0003567_abnormal_fetal_cardiomyocyte | 1.48251417 |
| 38 | MP0008057_abnormal_DNA_replication | 1.47558080 |
| 39 | MP0002148_abnormal_hypersensitivity_rea | 1.45534817 |
| 40 | MP0002006_tumorigenesis | 1.42771608 |
| 41 | MP0003111_abnormal_nucleus_morphology | 1.40201417 |
| 42 | MP0000371_diluted_coat_color | 1.30037424 |
| 43 | MP0004957_abnormal_blastocyst_morpholog | 1.29344324 |
| 44 | MP0008995_early_reproductive_senescence | 1.26949125 |
| 45 | MP0006054_spinal_hemorrhage | 1.26937380 |
| 46 | MP0005645_abnormal_hypothalamus_physiol | 1.26671422 |
| 47 | MP0009785_altered_susceptibility_to | 1.26601702 |
| 48 | MP0000647_abnormal_sebaceous_gland | 1.26392772 |
| 49 | MP0000685_abnormal_immune_system | 1.25709067 |
| 50 | MP0004215_abnormal_myocardial_fiber | 1.25566112 |
| 51 | MP0005253_abnormal_eye_physiology | 1.23647454 |
| 52 | MP0003718_maternal_effect | 1.23095396 |
| 53 | MP0000613_abnormal_salivary_gland | 1.21294143 |
| 54 | MP0004885_abnormal_endolymph | 1.21084735 |
| 55 | MP0006072_abnormal_retinal_apoptosis | 1.20148544 |
| 56 | MP0005646_abnormal_pituitary_gland | 1.19499595 |
| 57 | MP0002138_abnormal_hepatobiliary_system | 1.11580474 |
| 58 | MP0001800_abnormal_humoral_immune | 1.07298405 |
| 59 | MP0002751_abnormal_autonomic_nervous | 1.05243536 |
| 60 | MP0004019_abnormal_vitamin_homeostasis | 1.05144031 |
| 61 | MP0001905_abnormal_dopamine_level | 1.04734353 |
| 62 | MP0005085_abnormal_gallbladder_physiolo | 0.95312576 |
| 63 | MP0001727_abnormal_embryo_implantation | 0.90784406 |
| 64 | MP0005387_immune_system_phenotype | 0.90681695 |
| 65 | MP0001790_abnormal_immune_system | 0.90681695 |
| 66 | MP0004381_abnormal_hair_follicle | 0.90135823 |
| 67 | MP0002089_abnormal_postnatal_growth/wei | 0.87461583 |
| 68 | MP0002277_abnormal_respiratory_mucosa | 0.86584515 |
| 69 | MP0008877_abnormal_DNA_methylation | 0.84387061 |
| 70 | MP0002282_abnormal_trachea_morphology | 0.84275141 |
| 71 | MP0002876_abnormal_thyroid_physiology | 0.83339680 |
| 72 | MP0001119_abnormal_female_reproductive | 0.81541006 |
| 73 | MP0006292_abnormal_olfactory_placode | 0.81378364 |
| 74 | MP0000639_abnormal_adrenal_gland | 0.81302497 |
| 75 | MP0001765_abnormal_ion_homeostasis | 0.81068678 |
| 76 | MP0002127_abnormal_cardiovascular_syste | 0.80862870 |
| 77 | MP0002938_white_spotting | 0.78501871 |
| 78 | MP0002272_abnormal_nervous_system | 0.78417291 |
| 79 | MP0004145_abnormal_muscle_electrophysio | 0.76773449 |
| 80 | MP0003638_abnormal_response/metabolism_ | 0.76615844 |
| 81 | MP0005389_reproductive_system_phenotype | 0.74597271 |
| 82 | MP0004742_abnormal_vestibular_system | 0.74306917 |
| 83 | MP0000631_abnormal_neuroendocrine_gland | 0.74184441 |
| 84 | MP0001485_abnormal_pinna_reflex | 0.73232237 |
| 85 | MP0003183_abnormal_peptide_metabolism | 0.72932712 |
| 86 | MP0005000_abnormal_immune_tolerance | 0.71981061 |
| 87 | MP0000689_abnormal_spleen_morphology | 0.71700568 |
| 88 | MP0009046_muscle_twitch | 0.71273492 |
| 89 | MP0002160_abnormal_reproductive_system | 0.70370760 |
| 90 | MP0002723_abnormal_immune_serum | 0.68688602 |
| 91 | MP0009764_decreased_sensitivity_to | 0.68229573 |
| 92 | MP0002837_dystrophic_cardiac_calcinosis | 0.65545640 |
| 93 | MP0002452_abnormal_antigen_presenting | 0.65387781 |
| 94 | MP0002075_abnormal_coat/hair_pigmentati | 0.64105789 |
| 95 | MP0000653_abnormal_sex_gland | 0.63781427 |
| 96 | MP0005670_abnormal_white_adipose | 0.63549477 |
| 97 | MP0003136_yellow_coat_color | 0.63403122 |
| 98 | MP0001661_extended_life_span | 0.63366941 |
| 99 | MP0002822_catalepsy | 0.63167833 |
| 100 | MP0003077_abnormal_cell_cycle | 0.62789074 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 4.54886332 |
| 2 | Increased CSF lactate (HP:0002490) | 4.04993977 |
| 3 | Acute encephalopathy (HP:0006846) | 3.96652043 |
| 4 | Mitochondrial inheritance (HP:0001427) | 3.94284650 |
| 5 | Progressive macrocephaly (HP:0004481) | 3.89421408 |
| 6 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.82182751 |
| 7 | Hepatocellular necrosis (HP:0001404) | 3.73869429 |
| 8 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 3.65559448 |
| 9 | Absent/shortened dynein arms (HP:0200106) | 3.65559448 |
| 10 | Hepatic necrosis (HP:0002605) | 3.59352171 |
| 11 | Congenital stationary night blindness (HP:0007642) | 3.28657888 |
| 12 | Severe combined immunodeficiency (HP:0004430) | 3.27890966 |
| 13 | Thyroiditis (HP:0100646) | 3.26717744 |
| 14 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.13511762 |
| 15 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 3.09441604 |
| 16 | Hypoplasia of the fovea (HP:0007750) | 3.09441604 |
| 17 | Panhypogammaglobulinemia (HP:0003139) | 2.94596445 |
| 18 | Congenital, generalized hypertrichosis (HP:0004540) | 2.91471211 |
| 19 | Cerebral edema (HP:0002181) | 2.90972987 |
| 20 | Aplasia/Hypoplasia of the macula (HP:0008059) | 2.85604074 |
| 21 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.78510699 |
| 22 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.78510699 |
| 23 | Increased hepatocellular lipid droplets (HP:0006565) | 2.76322384 |
| 24 | Increased serum lactate (HP:0002151) | 2.75968036 |
| 25 | Renal Fanconi syndrome (HP:0001994) | 2.73324936 |
| 26 | Abnormality of the prostate (HP:0008775) | 2.72281269 |
| 27 | B lymphocytopenia (HP:0010976) | 2.70415252 |
| 28 | IgG deficiency (HP:0004315) | 2.66458461 |
| 29 | Aplasia/Hypoplasia affecting the retina (HP:0008061) | 2.66424048 |
| 30 | Pancreatic cysts (HP:0001737) | 2.65824304 |
| 31 | Generalized aminoaciduria (HP:0002909) | 2.63805044 |
| 32 | Combined immunodeficiency (HP:0005387) | 2.61851885 |
| 33 | Abnormality of the fovea (HP:0000493) | 2.61457814 |
| 34 | Congenital sensorineural hearing impairment (HP:0008527) | 2.60427983 |
| 35 | Abnormal spermatogenesis (HP:0008669) | 2.52326437 |
| 36 | Hypothermia (HP:0002045) | 2.52042183 |
| 37 | Increased serum pyruvate (HP:0003542) | 2.50525478 |
| 38 | Abnormality of B cell number (HP:0010975) | 2.44003678 |
| 39 | Molar tooth sign on MRI (HP:0002419) | 2.41208681 |
| 40 | Abnormality of midbrain morphology (HP:0002418) | 2.41208681 |
| 41 | Lipid accumulation in hepatocytes (HP:0006561) | 2.39692010 |
| 42 | Lactic acidosis (HP:0003128) | 2.33078831 |
| 43 | Azoospermia (HP:0000027) | 2.29874127 |
| 44 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.27409212 |
| 45 | Stomatitis (HP:0010280) | 2.26721151 |
| 46 | Respiratory failure (HP:0002878) | 2.26062075 |
| 47 | True hermaphroditism (HP:0010459) | 2.25899827 |
| 48 | Submucous cleft hard palate (HP:0000176) | 2.25360866 |
| 49 | Abnormality of eosinophils (HP:0001879) | 2.23131111 |
| 50 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.20356867 |
| 51 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.20356867 |
| 52 | Rough bone trabeculation (HP:0100670) | 2.18411200 |
| 53 | Abnormality of methionine metabolism (HP:0010901) | 2.18246437 |
| 54 | Progressive inability to walk (HP:0002505) | 2.17841920 |
| 55 | Abnormality of glycolysis (HP:0004366) | 2.17626269 |
| 56 | Optic disc pallor (HP:0000543) | 2.17348580 |
| 57 | 3-Methylglutaconic aciduria (HP:0003535) | 2.15083108 |
| 58 | Hypoproteinemia (HP:0003075) | 2.14345712 |
| 59 | Abnormality of renal resorption (HP:0011038) | 2.10602772 |
| 60 | Prostate neoplasm (HP:0100787) | 2.08367168 |
| 61 | Palpitations (HP:0001962) | 2.08124363 |
| 62 | Adrenal hypoplasia (HP:0000835) | 2.06154169 |
| 63 | Progressive microcephaly (HP:0000253) | 2.05844053 |
| 64 | Opisthotonus (HP:0002179) | 2.03617667 |
| 65 | Eosinophilia (HP:0001880) | 2.03102913 |
| 66 | Exertional dyspnea (HP:0002875) | 2.03096988 |
| 67 | Pancreatic fibrosis (HP:0100732) | 2.02698560 |
| 68 | Agammaglobulinemia (HP:0004432) | 2.02665022 |
| 69 | Cerebral hypomyelination (HP:0006808) | 1.99580001 |
| 70 | Lethargy (HP:0001254) | 1.99309893 |
| 71 | Aplastic anemia (HP:0001915) | 1.97334366 |
| 72 | Leukodystrophy (HP:0002415) | 1.94836066 |
| 73 | Nausea (HP:0002018) | 1.94719897 |
| 74 | Facial diplegia (HP:0001349) | 1.94624571 |
| 75 | Abnormality of the labia minora (HP:0012880) | 1.94197563 |
| 76 | Tongue fasciculations (HP:0001308) | 1.94166035 |
| 77 | Oral leukoplakia (HP:0002745) | 1.94145748 |
| 78 | Exercise intolerance (HP:0003546) | 1.93147771 |
| 79 | Abnormal lung lobation (HP:0002101) | 1.92484286 |
| 80 | Mesangial abnormality (HP:0001966) | 1.91365083 |
| 81 | Hypomagnesemia (HP:0002917) | 1.87281567 |
| 82 | Abolished electroretinogram (ERG) (HP:0000550) | 1.86653344 |
| 83 | Abnormal ciliary motility (HP:0012262) | 1.85557722 |
| 84 | Symptomatic seizures (HP:0011145) | 1.81801857 |
| 85 | Constricted visual fields (HP:0001133) | 1.81145084 |
| 86 | Abnormality of macular pigmentation (HP:0008002) | 1.79706601 |
| 87 | Supernumerary spleens (HP:0009799) | 1.78941458 |
| 88 | Chronic otitis media (HP:0000389) | 1.78111231 |
| 89 | Methylmalonic acidemia (HP:0002912) | 1.77136244 |
| 90 | Abnormality of urine glucose concentration (HP:0011016) | 1.76060106 |
| 91 | Glycosuria (HP:0003076) | 1.76060106 |
| 92 | Autoimmune hemolytic anemia (HP:0001890) | 1.75959192 |
| 93 | Polydipsia (HP:0001959) | 1.75609792 |
| 94 | Abnormal drinking behavior (HP:0030082) | 1.75609792 |
| 95 | Palpebral edema (HP:0100540) | 1.75484064 |
| 96 | Abnormality of the renal cortex (HP:0011035) | 1.73455346 |
| 97 | Inability to walk (HP:0002540) | 1.73380741 |
| 98 | J-shaped sella turcica (HP:0002680) | 1.71440019 |
| 99 | IgM deficiency (HP:0002850) | 1.71040915 |
| 100 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 1.70236678 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | STK16 | 3.54711529 |
| 2 | VRK2 | 3.50460206 |
| 3 | NUAK1 | 3.36108127 |
| 4 | EIF2AK3 | 3.19264835 |
| 5 | MST4 | 3.10479734 |
| 6 | CCNB1 | 2.66564914 |
| 7 | TSSK6 | 2.62776455 |
| 8 | MAP3K12 | 2.54964435 |
| 9 | EIF2AK1 | 2.41829844 |
| 10 | TXK | 2.25279103 |
| 11 | FRK | 2.16196748 |
| 12 | NEK1 | 2.01472534 |
| 13 | BUB1 | 1.92811628 |
| 14 | PDK2 | 1.85622794 |
| 15 | NME1 | 1.80089230 |
| 16 | WNK4 | 1.75052611 |
| 17 | PLK3 | 1.74991639 |
| 18 | TNIK | 1.69860336 |
| 19 | PLK2 | 1.66334037 |
| 20 | DAPK1 | 1.63188303 |
| 21 | PLK4 | 1.60021004 |
| 22 | VRK1 | 1.59519127 |
| 23 | TAF1 | 1.57091546 |
| 24 | TLK1 | 1.39831475 |
| 25 | MAPK13 | 1.38347291 |
| 26 | WEE1 | 1.32231308 |
| 27 | TEC | 1.27821780 |
| 28 | MAPKAPK3 | 1.23541078 |
| 29 | CSNK1G2 | 1.22646493 |
| 30 | CSNK1G3 | 1.20834066 |
| 31 | MYLK | 1.19030430 |
| 32 | GRK1 | 1.18976412 |
| 33 | CAMKK2 | 1.18848304 |
| 34 | TESK1 | 1.16953890 |
| 35 | ADRBK2 | 1.16529464 |
| 36 | TAOK3 | 1.16258946 |
| 37 | STK39 | 1.13814513 |
| 38 | BMPR1B | 1.13435547 |
| 39 | EIF2AK2 | 1.11598957 |
| 40 | GRK5 | 1.05824570 |
| 41 | TRIM28 | 1.05258068 |
| 42 | ILK | 1.04539763 |
| 43 | CSNK1A1L | 1.03470149 |
| 44 | CSNK1G1 | 1.02285004 |
| 45 | MAP4K2 | 0.97362898 |
| 46 | OXSR1 | 0.96998850 |
| 47 | TTK | 0.94688031 |
| 48 | ITK | 0.89070770 |
| 49 | PTK2B | 0.88626837 |
| 50 | STK38L | 0.87499412 |
| 51 | IRAK1 | 0.87293924 |
| 52 | PHKG2 | 0.80903342 |
| 53 | PHKG1 | 0.80903342 |
| 54 | BRSK2 | 0.79114852 |
| 55 | ZAK | 0.74966657 |
| 56 | MKNK2 | 0.74445921 |
| 57 | ERBB3 | 0.72026875 |
| 58 | KDR | 0.71958307 |
| 59 | TIE1 | 0.71912229 |
| 60 | WNK3 | 0.70952048 |
| 61 | NLK | 0.65250083 |
| 62 | BMPR2 | 0.64294340 |
| 63 | SRPK1 | 0.63933605 |
| 64 | SYK | 0.62325657 |
| 65 | ADRBK1 | 0.61977409 |
| 66 | PBK | 0.61140889 |
| 67 | MAPKAPK5 | 0.60132456 |
| 68 | PIK3CG | 0.59309706 |
| 69 | DYRK2 | 0.56524717 |
| 70 | MKNK1 | 0.55887519 |
| 71 | BRSK1 | 0.55313527 |
| 72 | DAPK3 | 0.55025403 |
| 73 | CDK8 | 0.54905949 |
| 74 | LIMK1 | 0.54282184 |
| 75 | INSRR | 0.49731076 |
| 76 | BCKDK | 0.48864623 |
| 77 | PLK1 | 0.47008048 |
| 78 | CAMK2A | 0.46969720 |
| 79 | PINK1 | 0.46527826 |
| 80 | IKBKE | 0.45426693 |
| 81 | ATR | 0.45042960 |
| 82 | FER | 0.44487019 |
| 83 | CDC7 | 0.42024888 |
| 84 | BCR | 0.41865028 |
| 85 | IKBKB | 0.40774727 |
| 86 | NME2 | 0.40710507 |
| 87 | SIK3 | 0.38903814 |
| 88 | STK10 | 0.36523042 |
| 89 | IGF1R | 0.36269841 |
| 90 | PRKCE | 0.34449124 |
| 91 | CSNK2A1 | 0.34431590 |
| 92 | OBSCN | 0.33971194 |
| 93 | AURKB | 0.31777365 |
| 94 | WNK1 | 0.31378900 |
| 95 | PRKG1 | 0.30366845 |
| 96 | CAMK2D | 0.29971159 |
| 97 | LYN | 0.29010542 |
| 98 | RIPK4 | 0.28744571 |
| 99 | PAK3 | 0.28580980 |
| 100 | PRKCA | 0.28145545 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 6.37985435 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.25397250 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.07967991 |
| 4 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.65312861 |
| 5 | Homologous recombination_Homo sapiens_hsa03440 | 2.41860695 |
| 6 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.20264755 |
| 7 | Protein export_Homo sapiens_hsa03060 | 2.12686447 |
| 8 | DNA replication_Homo sapiens_hsa03030 | 2.01081020 |
| 9 | Alzheimers disease_Homo sapiens_hsa05010 | 1.94619314 |
| 10 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.86513325 |
| 11 | Asthma_Homo sapiens_hsa05310 | 1.86234131 |
| 12 | Mismatch repair_Homo sapiens_hsa03430 | 1.84226384 |
| 13 | Huntingtons disease_Homo sapiens_hsa05016 | 1.83132371 |
| 14 | RNA polymerase_Homo sapiens_hsa03020 | 1.78566854 |
| 15 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.76952927 |
| 16 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.73928325 |
| 17 | Allograft rejection_Homo sapiens_hsa05330 | 1.58618966 |
| 18 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.51455480 |
| 19 | Ribosome_Homo sapiens_hsa03010 | 1.50578089 |
| 20 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.49146833 |
| 21 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.44919350 |
| 22 | RNA degradation_Homo sapiens_hsa03018 | 1.42677502 |
| 23 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.38524926 |
| 24 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.32794569 |
| 25 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.31134898 |
| 26 | RNA transport_Homo sapiens_hsa03013 | 1.28973766 |
| 27 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.28902011 |
| 28 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.28583206 |
| 29 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.28124113 |
| 30 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.26916848 |
| 31 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.23755387 |
| 32 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.22943840 |
| 33 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.21663160 |
| 34 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.19785358 |
| 35 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.18215463 |
| 36 | Purine metabolism_Homo sapiens_hsa00230 | 1.15515906 |
| 37 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.14588571 |
| 38 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.12324560 |
| 39 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.12115772 |
| 40 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.11953986 |
| 41 | Phototransduction_Homo sapiens_hsa04744 | 1.10515312 |
| 42 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.07803691 |
| 43 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.04246087 |
| 44 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.03776716 |
| 45 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.01304210 |
| 46 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.99695804 |
| 47 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.98960025 |
| 48 | Spliceosome_Homo sapiens_hsa03040 | 0.98832492 |
| 49 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.97313390 |
| 50 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.95509575 |
| 51 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.95206004 |
| 52 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.95005095 |
| 53 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.92373697 |
| 54 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.86386068 |
| 55 | Basal transcription factors_Homo sapiens_hsa03022 | 0.86338363 |
| 56 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.85033478 |
| 57 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.84543147 |
| 58 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.83883746 |
| 59 | Peroxisome_Homo sapiens_hsa04146 | 0.83087304 |
| 60 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.82622751 |
| 61 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.81593953 |
| 62 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.80743811 |
| 63 | Base excision repair_Homo sapiens_hsa03410 | 0.79496735 |
| 64 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.73644639 |
| 65 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.72104743 |
| 66 | Sulfur relay system_Homo sapiens_hsa04122 | 0.70534360 |
| 67 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.70020614 |
| 68 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.67749647 |
| 69 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.67517834 |
| 70 | Metabolic pathways_Homo sapiens_hsa01100 | 0.62685312 |
| 71 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.62573883 |
| 72 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.61258486 |
| 73 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.54849744 |
| 74 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.54664612 |
| 75 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.53471820 |
| 76 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.52022813 |
| 77 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.51901241 |
| 78 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.51645017 |
| 79 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.45181431 |
| 80 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.44810511 |
| 81 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.44693938 |
| 82 | Olfactory transduction_Homo sapiens_hsa04740 | 0.41124440 |
| 83 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.40066537 |
| 84 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.39320707 |
| 85 | Legionellosis_Homo sapiens_hsa05134 | 0.39286160 |
| 86 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.38918299 |
| 87 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.38093600 |
| 88 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.38034537 |
| 89 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.37991694 |
| 90 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.37500815 |
| 91 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.37030473 |
| 92 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.36771428 |
| 93 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.34554588 |
| 94 | Cell cycle_Homo sapiens_hsa04110 | 0.34489344 |
| 95 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.30770867 |
| 96 | Mineral absorption_Homo sapiens_hsa04978 | 0.29529551 |
| 97 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.27139264 |
| 98 | Retinol metabolism_Homo sapiens_hsa00830 | 0.25576266 |
| 99 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.23217663 |
| 100 | Morphine addiction_Homo sapiens_hsa05032 | 0.22987011 |

