SLC25A6P3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neuron remodeling (GO:0016322)7.03395858
2regulation of mitotic spindle organization (GO:0060236)7.02390322
3S-adenosylmethionine metabolic process (GO:0046500)6.00759200
4positive regulation of triglyceride biosynthetic process (GO:0010867)5.48527959
5lateral sprouting from an epithelium (GO:0060601)5.27265091
6DNA double-strand break processing (GO:0000729)5.25576767
7keratinocyte development (GO:0003334)5.04340198
8regulation of hippo signaling (GO:0035330)4.94765991
9tryptophan catabolic process (GO:0006569)4.76729252
10indole-containing compound catabolic process (GO:0042436)4.76729252
11indolalkylamine catabolic process (GO:0046218)4.76729252
12mRNA modification (GO:0016556)4.72297642
13positive regulation of receptor activity (GO:2000273)4.63059639
14substrate-dependent cell migration (GO:0006929)4.57013893
15regulation of transforming growth factor beta2 production (GO:0032909)4.56664506
16regulation of spindle organization (GO:0090224)4.48612627
17positive regulation of glycoprotein biosynthetic process (GO:0010560)4.26107406
18regulation of triglyceride biosynthetic process (GO:0010866)4.11085014
19regulation of meiosis I (GO:0060631)4.10672723
20tryptophan metabolic process (GO:0006568)4.06562376
21cornea development in camera-type eye (GO:0061303)4.05886800
22sulfation (GO:0051923)4.01235506
23glial cell proliferation (GO:0014009)4.01198012
24genitalia morphogenesis (GO:0035112)3.99299817
25retinal cone cell development (GO:0046549)3.95269850
26histone H3-K4 trimethylation (GO:0080182)3.90599584
27hindbrain development (GO:0030902)3.86583574
28protein K11-linked deubiquitination (GO:0035871)3.82608492
29heparin metabolic process (GO:0030202)3.76742527
30heparin biosynthetic process (GO:0030210)3.76742527
31DNA replication checkpoint (GO:0000076)3.71524505
32organ formation (GO:0048645)3.69401857
33oligosaccharide biosynthetic process (GO:0009312)3.64643810
34generation of neurons (GO:0048699)3.63989709
35negative regulation of translational initiation (GO:0045947)3.61739126
36positive regulation of T cell differentiation in thymus (GO:0033089)3.60663698
37RNA destabilization (GO:0050779)3.56697415
38head development (GO:0060322)3.56624244
39indolalkylamine metabolic process (GO:0006586)3.56246200
40adaptation of signaling pathway (GO:0023058)3.46264252
41aromatic amino acid family catabolic process (GO:0009074)3.46148269
42cellular response to virus (GO:0098586)3.45137176
43estrogen metabolic process (GO:0008210)3.43023185
44peptidyl-lysine trimethylation (GO:0018023)3.42991423
45regulation of mitotic spindle checkpoint (GO:1903504)3.39303451
46regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.39303451
47epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)3.39098671
48embryonic hemopoiesis (GO:0035162)3.35898529
49neuron maturation (GO:0042551)3.33476358
503-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)3.33120722
51purine ribonucleoside bisphosphate metabolic process (GO:0034035)3.33120722
52transmission of nerve impulse (GO:0019226)3.32401901
53regulation of alternative mRNA splicing, via spliceosome (GO:0000381)3.30377691
54negative regulation of transcription by competitive promoter binding (GO:0010944)3.26689747
55ephrin receptor signaling pathway (GO:0048013)3.25732698
56flavonoid metabolic process (GO:0009812)3.23225118
57positive regulation of developmental pigmentation (GO:0048087)3.22861877
58protein export from nucleus (GO:0006611)3.21763889
59positive regulation of triglyceride metabolic process (GO:0090208)3.13139496
60morphogenesis of an epithelial fold (GO:0060571)3.12569410
61histone lysine methylation (GO:0034968)3.11067184
62positive regulation of fibroblast migration (GO:0010763)3.10853215
63tRNA modification (GO:0006400)3.09131150
64centriole replication (GO:0007099)3.08120641
65detection of light stimulus involved in sensory perception (GO:0050962)3.01414047
66detection of light stimulus involved in visual perception (GO:0050908)3.01414047
67DNA packaging (GO:0006323)2.98833409
68positive regulation of glycoprotein metabolic process (GO:1903020)2.98334490
69negative regulation of neurotransmitter secretion (GO:0046929)2.97805629
70limb bud formation (GO:0060174)2.95809471
71cellular biogenic amine catabolic process (GO:0042402)2.94011786
72amine catabolic process (GO:0009310)2.94011786
73piRNA metabolic process (GO:0034587)2.92136778
74negative regulation of translation, ncRNA-mediated (GO:0040033)2.89361752
75regulation of translation, ncRNA-mediated (GO:0045974)2.89361752
76negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.89361752
77positive regulation of RNA splicing (GO:0033120)2.88909766
78recombinational repair (GO:0000725)2.88889283
79double-strand break repair via homologous recombination (GO:0000724)2.88261500
80pancreas development (GO:0031016)2.87689956
81nuclear pore complex assembly (GO:0051292)2.84114574
82positive regulation of fatty acid transport (GO:2000193)2.82729538
83somatic stem cell maintenance (GO:0035019)2.80263400
84mitochondrial outer membrane permeabilization involved in programmed cell death (GO:1902686)2.80137404
85positive regulation of mitochondrial membrane permeability involved in apoptotic process (GO:19021102.80137404
86kynurenine metabolic process (GO:0070189)2.79845596
87intra-S DNA damage checkpoint (GO:0031573)2.79807649
88left/right axis specification (GO:0070986)2.77847618
89mannosylation (GO:0097502)2.77323494
90negative regulation of endothelial cell apoptotic process (GO:2000352)2.77310220
91polyol transport (GO:0015791)2.74518485
92positive regulation of receptor internalization (GO:0002092)2.74224911
93pore complex assembly (GO:0046931)2.73873774
94regulation of MHC class I biosynthetic process (GO:0045343)2.73163766
95regulation of viral entry into host cell (GO:0046596)2.70233034
96adenosine metabolic process (GO:0046085)2.68104506
97negative regulation of fibroblast growth factor receptor signaling pathway (GO:0040037)2.68054411
98phosphatidylglycerol biosynthetic process (GO:0006655)2.67639959
99protein targeting to vacuole (GO:0006623)2.67532579
100establishment of protein localization to vacuole (GO:0072666)2.67532579

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1STAT6_21828071_ChIP-Seq_BEAS2B_Human4.15087587
2ZNF274_21170338_ChIP-Seq_K562_Hela3.32178990
3HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.27255237
4GBX2_23144817_ChIP-Seq_PC3_Human3.11798163
5MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.80234618
6KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.78247938
7CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.33748271
8GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.30207571
9CHD7_19251738_ChIP-ChIP_MESCs_Mouse2.23467739
10TAF15_26573619_Chip-Seq_HEK293_Human2.23312331
11VDR_22108803_ChIP-Seq_LS180_Human2.22503584
12POU3F2_20337985_ChIP-ChIP_501MEL_Human2.18427311
13FLI1_27457419_Chip-Seq_LIVER_Mouse2.02958817
14AHR_22903824_ChIP-Seq_MCF-7_Human2.01432793
15SUZ12_27294783_Chip-Seq_NPCs_Mouse2.00431572
16ZFP57_27257070_Chip-Seq_ESCs_Mouse1.99954944
17PKCTHETA_26484144_Chip-Seq_BREAST_Human1.98453561
18PCGF2_27294783_Chip-Seq_ESCs_Mouse1.97631090
19CTBP2_25329375_ChIP-Seq_LNCAP_Human1.87040409
20ESR1_20079471_ChIP-ChIP_T-47D_Human1.84810200
21HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.84727202
22MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.84135931
23CBP_20019798_ChIP-Seq_JUKART_Human1.80774712
24IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.80774712
25FUS_26573619_Chip-Seq_HEK293_Human1.78153477
26PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.75103488
27AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.73040588
28NFE2_27457419_Chip-Seq_LIVER_Mouse1.72974855
29POU5F1_16153702_ChIP-ChIP_HESCs_Human1.72482480
30P300_19829295_ChIP-Seq_ESCs_Human1.67279757
31ARNT_22903824_ChIP-Seq_MCF-7_Human1.59848075
32IGF1R_20145208_ChIP-Seq_DFB_Human1.54903217
33PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.54313804
34PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.52937020
35EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.50672007
36EZH2_27294783_Chip-Seq_NPCs_Mouse1.47004858
37TCF4_22108803_ChIP-Seq_LS180_Human1.46448174
38SUZ12_18555785_Chip-Seq_ESCs_Mouse1.45896840
39PCGF2_27294783_Chip-Seq_NPCs_Mouse1.44125226
40EWS_26573619_Chip-Seq_HEK293_Human1.43303456
41CTBP1_25329375_ChIP-Seq_LNCAP_Human1.42526863
42DCP1A_22483619_ChIP-Seq_HELA_Human1.41797449
43NCOR_22424771_ChIP-Seq_293T_Human1.41048495
44GATA3_21878914_ChIP-Seq_MCF-7_Human1.37335314
45EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.36545130
46TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.35875867
47GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.35547607
48AUTS2_25519132_ChIP-Seq_293T-REX_Human1.34013210
49FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.33688598
50ESR1_15608294_ChIP-ChIP_MCF-7_Human1.33334739
51KLF5_20875108_ChIP-Seq_MESCs_Mouse1.32783633
52CRX_20693478_ChIP-Seq_RETINA_Mouse1.29248111
53PHF8_20622853_ChIP-Seq_HELA_Human1.28241697
54EGR1_23403033_ChIP-Seq_LIVER_Mouse1.26570183
55UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.26556859
56ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.26315730
57NANOG_18555785_Chip-Seq_ESCs_Mouse1.25945650
58MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.23921243
59FOXA1_21572438_ChIP-Seq_LNCaP_Human1.23135260
60SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.22549822
61TCF4_23295773_ChIP-Seq_U87_Human1.21322671
62SMAD4_21741376_ChIP-Seq_EPCs_Human1.21172108
63E2F1_18555785_Chip-Seq_ESCs_Mouse1.20725597
64SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.20201371
65CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.20195676
66FOXM1_26456572_ChIP-Seq_MCF-7_Human1.19927027
67STAT3_23295773_ChIP-Seq_U87_Human1.18891492
68RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.16095055
69GATA1_22025678_ChIP-Seq_K562_Human1.15774117
70MYC_18940864_ChIP-ChIP_HL60_Human1.14977946
71CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.14694858
72P300_18555785_Chip-Seq_ESCs_Mouse1.14190061
73CTNNB1_20460455_ChIP-Seq_HCT116_Human1.14089176
74ETV2_25802403_ChIP-Seq_MESCs_Mouse1.13462076
75IRF8_22096565_ChIP-ChIP_GC-B_Human1.12494287
76BCAT_22108803_ChIP-Seq_LS180_Human1.11678545
77NMYC_18555785_Chip-Seq_ESCs_Mouse1.11572061
78ELK4_26923725_Chip-Seq_MESODERM_Mouse1.11324945
79PIAS1_25552417_ChIP-Seq_VCAP_Human1.10572314
80SALL1_21062744_ChIP-ChIP_HESCs_Human1.10484614
81P53_22387025_ChIP-Seq_ESCs_Mouse1.10375714
82SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.09687833
83RBPJ_21746931_ChIP-Seq_IB4_Human1.09444567
84ER_23166858_ChIP-Seq_MCF-7_Human1.09424544
85TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.09400142
86VDR_23849224_ChIP-Seq_CD4+_Human1.09351055
87AR_25329375_ChIP-Seq_VCAP_Human1.08788080
88FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.08370306
89TBL1_22424771_ChIP-Seq_293T_Human1.08273863
90BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.07255100
91NANOG_19829295_ChIP-Seq_ESCs_Human1.06542173
92SOX2_19829295_ChIP-Seq_ESCs_Human1.06542173
93FOXA1_27270436_Chip-Seq_PROSTATE_Human1.06495753
94FOXA1_25329375_ChIP-Seq_VCAP_Human1.06495753
95CDX2_21074721_ChIP-Seq_CACO-2_Mouse1.06027421
96SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.04819522
97STAT3_18555785_Chip-Seq_ESCs_Mouse1.04423805
98NFYB_21822215_ChIP-Seq_K562_Human1.04397389
99EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.04152144
100PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.03534588

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002160_abnormal_reproductive_system4.58797491
2MP0004147_increased_porphyrin_level4.40741102
3MP0001727_abnormal_embryo_implantation4.35777607
4MP0003172_abnormal_lysosome_physiology3.54479113
5MP0001919_abnormal_reproductive_system3.04328734
6MP0003693_abnormal_embryo_hatching2.67400548
7MP0005075_abnormal_melanosome_morpholog2.65140274
8MP0000015_abnormal_ear_pigmentation2.47185942
9MP0001188_hyperpigmentation2.45398482
10MP0005389_reproductive_system_phenotype2.26360785
11MP0001873_stomach_inflammation2.22254828
12MP0003950_abnormal_plasma_membrane2.20671214
13MP0000537_abnormal_urethra_morphology2.20099221
14MP0001346_abnormal_lacrimal_gland2.13802772
15MP0002138_abnormal_hepatobiliary_system2.11722237
16MP0002282_abnormal_trachea_morphology2.07722994
17MP0002102_abnormal_ear_morphology2.06596629
18MP0005551_abnormal_eye_electrophysiolog2.04473804
19MP0005646_abnormal_pituitary_gland1.97799145
20MP0001529_abnormal_vocalization1.92734479
21MP0009697_abnormal_copulation1.90746009
22MP0000383_abnormal_hair_follicle1.90271761
23MP0010094_abnormal_chromosome_stability1.87382238
24MP0006292_abnormal_olfactory_placode1.84944659
25MP0003718_maternal_effect1.80469351
26MP0000613_abnormal_salivary_gland1.71476857
27MP0003656_abnormal_erythrocyte_physiolo1.70504098
28MP0008058_abnormal_DNA_repair1.68905479
29MP0008872_abnormal_physiological_respon1.68275808
30MP0004808_abnormal_hematopoietic_stem1.62007650
31MP0003045_fibrosis1.58624257
32MP0000427_abnormal_hair_cycle1.58597553
33MP0005248_abnormal_Harderian_gland1.55622546
34MP0000569_abnormal_digit_pigmentation1.54459117
35MP0005410_abnormal_fertilization1.48535709
36MP0008877_abnormal_DNA_methylation1.47694999
37MP0005395_other_phenotype1.47539769
38MP0000647_abnormal_sebaceous_gland1.45487827
39MP0000467_abnormal_esophagus_morphology1.45382037
40MP0006072_abnormal_retinal_apoptosis1.44617070
41MP0002938_white_spotting1.44424852
42MP0003303_peritoneal_inflammation1.42229920
43MP0000631_abnormal_neuroendocrine_gland1.41782115
44MP0002168_other_aberrant_phenotype1.41193039
45MP0009333_abnormal_splenocyte_physiolog1.32056691
46MP0001764_abnormal_homeostasis1.29208984
47MP0005084_abnormal_gallbladder_morpholo1.28786445
48MP0003936_abnormal_reproductive_system1.22176416
49MP0001486_abnormal_startle_reflex1.21859338
50MP0000372_irregular_coat_pigmentation1.21465160
51MP0000627_abnormal_mammary_gland1.18409458
52MP0002254_reproductive_system_inflammat1.17221486
53MP0003698_abnormal_male_reproductive1.16681610
54MP0010678_abnormal_skin_adnexa1.16586130
55MP0004134_abnormal_chest_morphology1.14475491
56MP0003011_delayed_dark_adaptation1.13922945
57MP0003195_calcinosis1.09073766
58MP0001929_abnormal_gametogenesis1.08528739
59MP0000516_abnormal_urinary_system1.08277160
60MP0005367_renal/urinary_system_phenotyp1.08277160
61MP0000653_abnormal_sex_gland1.02396124
62MP0008007_abnormal_cellular_replicative1.02339993
63MP0004924_abnormal_behavior1.00203276
64MP0005386_behavior/neurological_phenoty1.00203276
65MP0001145_abnormal_male_reproductive1.00141236
66MP0000778_abnormal_nervous_system0.99826066
67MP0008995_early_reproductive_senescence0.98535289
68MP0002837_dystrophic_cardiac_calcinosis0.97098047
69MP0003786_premature_aging0.88777573
70MP0005253_abnormal_eye_physiology0.88580194
71MP0002098_abnormal_vibrissa_morphology0.87867103
72MP0001663_abnormal_digestive_system0.83835656
73MP0002638_abnormal_pupillary_reflex0.81008998
74MP0001485_abnormal_pinna_reflex0.80003951
75MP0000538_abnormal_urinary_bladder0.79375992
76MP0003252_abnormal_bile_duct0.79102559
77MP0000470_abnormal_stomach_morphology0.78944575
78MP0003787_abnormal_imprinting0.78671871
79MP0001851_eye_inflammation0.76960463
80MP0005187_abnormal_penis_morphology0.75257596
81MP0000049_abnormal_middle_ear0.73906034
82MP0005636_abnormal_mineral_homeostasis0.73250531
83MP0005085_abnormal_gallbladder_physiolo0.72111583
84MP0008789_abnormal_olfactory_epithelium0.69436918
85MP0003943_abnormal_hepatobiliary_system0.69395312
86MP0005464_abnormal_platelet_physiology0.68020334
87MP0005167_abnormal_blood-brain_barrier0.67656220
88MP0002557_abnormal_social/conspecific_i0.67057030
89MP0001177_atelectasis0.66964971
90MP0000371_diluted_coat_color0.66607284
91MP0002095_abnormal_skin_pigmentation0.66549487
92MP0002115_abnormal_skeleton_extremities0.65454557
93MP0005220_abnormal_exocrine_pancreas0.64306203
94MP0003121_genomic_imprinting0.63286274
95MP0010386_abnormal_urinary_bladder0.62841703
96MP0004133_heterotaxia0.62512487
97MP0005670_abnormal_white_adipose0.62061856
98MP0005365_abnormal_bile_salt0.61849217
99MP0002108_abnormal_muscle_morphology0.60566230
100MP0003763_abnormal_thymus_physiology0.57719992

Predicted human phenotypes

RankGene SetZ-score
1Hyperinsulinemic hypoglycemia (HP:0000825)6.63200339
2Albinism (HP:0001022)4.13597651
3Gonadotropin excess (HP:0000837)3.85725723
4Partial agenesis of the corpus callosum (HP:0001338)3.78833964
5Submucous cleft hard palate (HP:0000176)3.59275568
6Ectopic kidney (HP:0000086)3.55818692
7Hematochezia (HP:0002573)3.52693035
8Microretrognathia (HP:0000308)3.37871402
9Petechiae (HP:0000967)3.24146661
10Abnormality of midbrain morphology (HP:0002418)3.23454012
11Molar tooth sign on MRI (HP:0002419)3.23454012
12Thickened helices (HP:0000391)3.14198100
13Alveolar cell carcinoma (HP:0006519)3.00002684
14Action tremor (HP:0002345)2.99270437
15Exertional dyspnea (HP:0002875)2.99052895
16Abnormality of the proximal phalanges of the hand (HP:0009834)2.97261524
17Aplastic anemia (HP:0001915)2.91576721
18Duplicated collecting system (HP:0000081)2.82521768
19Neoplasm of the tracheobronchial system (HP:0100552)2.70004362
20High anterior hairline (HP:0009890)2.68730882
21Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026)2.66849526
22Short 1st metacarpal (HP:0010034)2.66849526
23Menstrual irregularities (HP:0000858)2.65674313
24Thyroid-stimulating hormone excess (HP:0002925)2.61769837
25Abnormality of the renal collecting system (HP:0004742)2.57112583
26Abnormality of the 1st metacarpal (HP:0010009)2.46716170
27Papilledema (HP:0001085)2.45965668
28Cystic hygroma (HP:0000476)2.45233037
29Pendular nystagmus (HP:0012043)2.44981536
30Wide nose (HP:0000445)2.43297645
31Nephronophthisis (HP:0000090)2.40109160
32Delayed CNS myelination (HP:0002188)2.39152380
33Abnormality of chromosome stability (HP:0003220)2.38280765
34Stomatitis (HP:0010280)2.35810020
35Selective tooth agenesis (HP:0001592)2.34316621
36Absent eyebrow (HP:0002223)2.34189361
37Curly hair (HP:0002212)2.26482192
38Depressed nasal tip (HP:0000437)2.24837334
39Abnormality of the middle phalanx of the 5th finger (HP:0004219)2.24339785
40Posterior subcapsular cataract (HP:0007787)2.23794587
41Attenuation of retinal blood vessels (HP:0007843)2.23760048
42Absent rod-and cone-mediated responses on ERG (HP:0007688)2.22016000
43Asplenia (HP:0001746)2.21000436
44Myelodysplasia (HP:0002863)2.20858543
45Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.19922923
46Abnormal protein N-linked glycosylation (HP:0012347)2.19922923
47Abnormal protein glycosylation (HP:0012346)2.19922923
48Abnormal glycosylation (HP:0012345)2.19922923
49Abnormal rod and cone electroretinograms (HP:0008323)2.19626699
50Abnormality of the renal medulla (HP:0100957)2.18015366
51Abnormality of the labia minora (HP:0012880)2.13710740
52Type I transferrin isoform profile (HP:0003642)2.13201282
53Narrow forehead (HP:0000341)2.12817791
54Tachypnea (HP:0002789)2.12373635
55Abnormality of the antihelix (HP:0009738)2.09985609
56Lissencephaly (HP:0001339)2.09555637
57Abnormality of the phalanges of the 5th finger (HP:0004213)2.08770318
58Increased CSF protein (HP:0002922)2.06520847
59Congenital stationary night blindness (HP:0007642)2.02956634
60Abnormal number of incisors (HP:0011064)2.01989873
61Pancreatic cysts (HP:0001737)2.01179324
62Anophthalmia (HP:0000528)2.01149811
63Severe visual impairment (HP:0001141)1.96785134
64Bulbous nose (HP:0000414)1.96442676
65Concave nail (HP:0001598)1.95565269
66Chronic hepatic failure (HP:0100626)1.93586529
67Colon cancer (HP:0003003)1.90870885
68Aplasia/Hypoplasia of the spleen (HP:0010451)1.89233092
69Opisthotonus (HP:0002179)1.88887803
70Dysdiadochokinesis (HP:0002075)1.87730322
71Fair hair (HP:0002286)1.86465220
72Chorioretinal atrophy (HP:0000533)1.85798277
73Impaired platelet aggregation (HP:0003540)1.85308775
74Abnormal platelet function (HP:0011869)1.85308775
75Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.84675989
76Epidermoid cyst (HP:0200040)1.83779950
77Short phalanx of the thumb (HP:0009660)1.83184911
78Abnormality of the pons (HP:0007361)1.82875299
79Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)1.82772035
80Absent eyelashes (HP:0000561)1.80035656
81Bile duct proliferation (HP:0001408)1.79991497
82Abnormal biliary tract physiology (HP:0012439)1.79991497
83Decreased electroretinogram (ERG) amplitude (HP:0000654)1.78757491
84Chromosomal breakage induced by crosslinking agents (HP:0003221)1.77684419
85Long clavicles (HP:0000890)1.77014010
86Abnormality of macular pigmentation (HP:0008002)1.76442196
87Absent hair (HP:0002298)1.74841486
88Heterotopia (HP:0002282)1.74668354
89Focal motor seizures (HP:0011153)1.73210593
90Intention tremor (HP:0002080)1.72584646
91Macular degeneration (HP:0000608)1.72401442
92Clumsiness (HP:0002312)1.70398875
93Abnormality of chromosome segregation (HP:0002916)1.69245487
94Poor eye contact (HP:0000817)1.69153213
95True hermaphroditism (HP:0010459)1.68998501
96Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376)1.68071636
97Lip pit (HP:0100267)1.67517880
98Optic nerve hypoplasia (HP:0000609)1.66904539
99Pancreatic islet-cell hyperplasia (HP:0004510)1.66674484
100Facial hemangioma (HP:0000329)1.65518800

Predicted kinase interactions (KEA)

RankGene SetZ-score
1AKT36.33114449
2TNIK5.70518440
3PNCK5.22478175
4MAP4K24.76429093
5CDK93.81679220
6NLK3.63126757
7GRK13.19297157
8EIF2AK32.58602019
9WEE12.51738894
10TTK2.18740900
11BRAF2.17742185
12MUSK1.91931432
13PLK41.83554648
14EPHB21.82575396
15NUAK11.77944867
16EPHA31.66296956
17PIM21.59490546
18EIF2AK11.52875549
19FRK1.44241047
20VRK11.43948159
21WNK31.41804459
22INSRR1.31416213
23CDC71.28750826
24BRSK21.28123088
25FER1.26848587
26SGK21.12696167
27TAF11.01169828
28PRKCE1.00092233
29MAP2K20.95815441
30DYRK20.92796829
31PAK30.92434747
32MAPKAPK50.88462977
33MAPKAPK30.84253831
34MELK0.81722249
35PIK3CA0.78061150
36VRK20.69348928
37MST40.68603025
38OXSR10.65895261
39CDK80.64887218
40ADRBK20.63510626
41PLK30.63206554
42TRIM280.59345130
43CAMK1G0.58720496
44CSNK1G20.56158983
45SGK4940.53822088
46SGK2230.53822088
47IKBKB0.53209303
48BCR0.53061402
49ZAK0.52861477
50PRKCG0.52036306
51SGK30.50982714
52EPHA40.50085210
53PINK10.49079278
54PRKCI0.47840649
55MAP2K10.47386005
56ATR0.46339701
57RPS6KB10.45207475
58ZAP700.44923113
59CHUK0.44838769
60MAPK30.44287809
61PIK3CG0.43893223
62CSNK1G30.42938551
63ABL10.42490769
64CSNK1A1L0.41704755
65MAP3K40.41440958
66TNK20.40357499
67RPS6KA40.39047813
68PLK10.38525813
69TLK10.38411974
70ABL20.37953524
71ERBB20.36939583
72ATM0.33210400
73DYRK30.32117999
74CSNK2A10.31728320
75MAPK10.31396642
76MAPK130.30757505
77CSNK1G10.29258875
78GSK3A0.28775731
79HIPK20.28660831
80RPS6KA50.28126373
81PLK20.27815134
82MKNK20.27135473
83IRAK10.22574492
84MAP2K60.22332828
85STK390.22108951
86CHEK20.21075606
87CDK30.19375470
88CSNK1D0.19086621
89LATS10.17633799
90STK38L0.17376770
91RPS6KA60.17133159
92CSNK2A20.17112737
93DYRK1A0.15959246
94MAPK110.15561583
95CSNK1E0.15505884
96PRKCZ0.14878606
97PRKD10.13164790
98CAMK10.12022134
99RPS6KL10.11999964
100RPS6KC10.11999964

Predicted pathways (KEGG)

RankGene SetZ-score
1Selenocompound metabolism_Homo sapiens_hsa004503.85519589
2Sulfur metabolism_Homo sapiens_hsa009203.31442959
3Thyroid cancer_Homo sapiens_hsa052162.98447231
4Lysine degradation_Homo sapiens_hsa003102.96521721
5Homologous recombination_Homo sapiens_hsa034402.91039987
6Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006012.41705581
7Basal transcription factors_Homo sapiens_hsa030222.35125940
8Fanconi anemia pathway_Homo sapiens_hsa034602.18795922
9alpha-Linolenic acid metabolism_Homo sapiens_hsa005922.10284267
10Nitrogen metabolism_Homo sapiens_hsa009102.08843124
11Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.00190366
12Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.96590229
13Tryptophan metabolism_Homo sapiens_hsa003801.93967243
14Linoleic acid metabolism_Homo sapiens_hsa005911.90333759
15Basal cell carcinoma_Homo sapiens_hsa052171.89404085
16beta-Alanine metabolism_Homo sapiens_hsa004101.87001028
17RNA degradation_Homo sapiens_hsa030181.85456076
18DNA replication_Homo sapiens_hsa030301.85172456
19Prostate cancer_Homo sapiens_hsa052151.74265977
20Butanoate metabolism_Homo sapiens_hsa006501.69455453
21Aldosterone synthesis and secretion_Homo sapiens_hsa049251.67430359
22Phototransduction_Homo sapiens_hsa047441.53574050
23Ether lipid metabolism_Homo sapiens_hsa005651.48299438
24Endometrial cancer_Homo sapiens_hsa052131.39523577
25Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.39358133
26Acute myeloid leukemia_Homo sapiens_hsa052211.37142943
27Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.36700850
28Chemical carcinogenesis_Homo sapiens_hsa052041.36192593
29Longevity regulating pathway - mammal_Homo sapiens_hsa042111.35608409
30Tight junction_Homo sapiens_hsa045301.28944958
31Histidine metabolism_Homo sapiens_hsa003401.24706665
32Fatty acid elongation_Homo sapiens_hsa000621.23458412
33ABC transporters_Homo sapiens_hsa020101.20545919
34Colorectal cancer_Homo sapiens_hsa052101.16748405
35RNA transport_Homo sapiens_hsa030131.15902758
36Pentose and glucuronate interconversions_Homo sapiens_hsa000401.10258912
37Vitamin digestion and absorption_Homo sapiens_hsa049771.08182068
38Thyroid hormone signaling pathway_Homo sapiens_hsa049191.04215032
39Nucleotide excision repair_Homo sapiens_hsa034201.00148182
40Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.96702455
41Protein export_Homo sapiens_hsa030600.94736725
42Cocaine addiction_Homo sapiens_hsa050300.94241895
43Hedgehog signaling pathway_Homo sapiens_hsa043400.92534102
44Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.92409514
45Steroid hormone biosynthesis_Homo sapiens_hsa001400.92127271
46Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.85453167
47p53 signaling pathway_Homo sapiens_hsa041150.82858652
48Mismatch repair_Homo sapiens_hsa034300.80918588
49Purine metabolism_Homo sapiens_hsa002300.80806374
50Peroxisome_Homo sapiens_hsa041460.78366982
51Primary bile acid biosynthesis_Homo sapiens_hsa001200.77835517
52Hippo signaling pathway_Homo sapiens_hsa043900.76197153
53Salivary secretion_Homo sapiens_hsa049700.75782422
54Tyrosine metabolism_Homo sapiens_hsa003500.75411107
55RNA polymerase_Homo sapiens_hsa030200.74047896
56Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.73929665
57Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.73467764
58Cell cycle_Homo sapiens_hsa041100.72477885
59Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.70619884
60Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.65702898
61Retinol metabolism_Homo sapiens_hsa008300.65041222
62Carbohydrate digestion and absorption_Homo sapiens_hsa049730.62340856
63Arachidonic acid metabolism_Homo sapiens_hsa005900.61580760
64Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.60963286
65Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.59779475
66mTOR signaling pathway_Homo sapiens_hsa041500.58740213
67Pyrimidine metabolism_Homo sapiens_hsa002400.58301561
68Non-homologous end-joining_Homo sapiens_hsa034500.57933401
69One carbon pool by folate_Homo sapiens_hsa006700.55695885
70Non-small cell lung cancer_Homo sapiens_hsa052230.55484671
71Sulfur relay system_Homo sapiens_hsa041220.55362470
72Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.50340142
73Melanoma_Homo sapiens_hsa052180.49737318
74Glycerophospholipid metabolism_Homo sapiens_hsa005640.49449019
75Ovarian steroidogenesis_Homo sapiens_hsa049130.48879000
76TGF-beta signaling pathway_Homo sapiens_hsa043500.46451739
77Thyroid hormone synthesis_Homo sapiens_hsa049180.46276990
78Pancreatic cancer_Homo sapiens_hsa052120.45840560
79Insulin secretion_Homo sapiens_hsa049110.45646194
80Jak-STAT signaling pathway_Homo sapiens_hsa046300.45243289
81RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.44606438
82Regulation of autophagy_Homo sapiens_hsa041400.44468685
83Caffeine metabolism_Homo sapiens_hsa002320.40989767
84Cysteine and methionine metabolism_Homo sapiens_hsa002700.40981891
85N-Glycan biosynthesis_Homo sapiens_hsa005100.40299698
86Bladder cancer_Homo sapiens_hsa052190.38402976
87Propanoate metabolism_Homo sapiens_hsa006400.37063583
88Base excision repair_Homo sapiens_hsa034100.34945770
89Pancreatic secretion_Homo sapiens_hsa049720.34827580
90Sphingolipid metabolism_Homo sapiens_hsa006000.34498496
91Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.31887364
92Fatty acid metabolism_Homo sapiens_hsa012120.31253529
93cAMP signaling pathway_Homo sapiens_hsa040240.31028930
94Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.30241235
95Wnt signaling pathway_Homo sapiens_hsa043100.30012795
96Circadian rhythm_Homo sapiens_hsa047100.29648348
97Alcoholism_Homo sapiens_hsa050340.29281326
98Hepatitis C_Homo sapiens_hsa051600.27504748
99Nicotine addiction_Homo sapiens_hsa050330.25843738
100Transcriptional misregulation in cancer_Homo sapiens_hsa052020.25823927

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »