SLC2A3P1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1N-glycan processing (GO:0006491)6.08509352
2nuclear pore complex assembly (GO:0051292)5.22830959
3neurotransmitter-gated ion channel clustering (GO:0072578)4.82410750
4phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)4.71636410
5cytoplasmic mRNA processing body assembly (GO:0033962)4.65602589
6peptidyl-lysine trimethylation (GO:0018023)4.35657270
7nuclear pore organization (GO:0006999)4.22127986
8embryonic hemopoiesis (GO:0035162)4.19635053
9presynaptic membrane assembly (GO:0097105)4.19532102
10regulation of pigment cell differentiation (GO:0050932)4.14397697
11chaperone-mediated protein complex assembly (GO:0051131)4.04427738
12positive regulation of developmental pigmentation (GO:0048087)3.99121176
13cell wall macromolecule catabolic process (GO:0016998)3.96100329
14histone H3-K4 trimethylation (GO:0080182)3.90050605
15SMAD protein complex assembly (GO:0007183)3.88387720
16pyrimidine nucleobase catabolic process (GO:0006208)3.85316163
17regulation of somitogenesis (GO:0014807)3.84830468
18negative regulation of neurotransmitter secretion (GO:0046929)3.77870853
19histone H3-K36 demethylation (GO:0070544)3.77205774
20negative regulation of neurotransmitter transport (GO:0051589)3.74776835
21regulation of Rac protein signal transduction (GO:0035020)3.67380329
22pore complex assembly (GO:0046931)3.66300966
23coronary vasculature morphogenesis (GO:0060977)3.60490934
24CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)3.58613165
25protein localization to synapse (GO:0035418)3.52128221
26negative regulation of DNA repair (GO:0045738)3.52070781
27regulation of RNA export from nucleus (GO:0046831)3.48846570
28heart valve formation (GO:0003188)3.46061356
29central nervous system projection neuron axonogenesis (GO:0021952)3.45821943
30olfactory bulb development (GO:0021772)3.42682251
31cell wall macromolecule metabolic process (GO:0044036)3.41901441
32vesicle transport along microtubule (GO:0047496)3.41337324
33presynaptic membrane organization (GO:0097090)3.40820460
34postsynaptic membrane organization (GO:0001941)3.40291337
35pre-miRNA processing (GO:0031054)3.31254845
36negative regulation of organelle assembly (GO:1902116)3.28207804
37vocalization behavior (GO:0071625)3.27950807
38opioid receptor signaling pathway (GO:0038003)3.27271249
39histone H2B ubiquitination (GO:0033523)3.19374029
40DNA topological change (GO:0006265)3.18074842
41activated T cell proliferation (GO:0050798)3.17685491
42positive regulation of interferon-gamma biosynthetic process (GO:0045078)3.16015052
43megakaryocyte development (GO:0035855)3.01131915
44righting reflex (GO:0060013)2.97102969
45negative regulation of Ras GTPase activity (GO:0034261)2.95803912
46negative regulation of G2/M transition of mitotic cell cycle (GO:0010972)2.95560566
47histone lysine demethylation (GO:0070076)2.93232340
48neuron cell-cell adhesion (GO:0007158)2.93018220
49DNA integration (GO:0015074)2.92581099
50establishment of protein localization to Golgi (GO:0072600)2.89926396
51regulation of nucleobase-containing compound transport (GO:0032239)2.88340563
52peptidyl-lysine methylation (GO:0018022)2.88032047
53sulfation (GO:0051923)2.83084476
54histone demethylation (GO:0016577)2.82038659
55myelin assembly (GO:0032288)2.81957738
56regulation of acyl-CoA biosynthetic process (GO:0050812)2.81770477
57protein K11-linked deubiquitination (GO:0035871)2.80798460
58retrograde transport, vesicle recycling within Golgi (GO:0000301)2.78322083
59platelet formation (GO:0030220)2.78195768
60histone H3-K4 methylation (GO:0051568)2.78190169
61protein targeting to Golgi (GO:0000042)2.76479425
62establishment of nucleus localization (GO:0040023)2.76465083
63histone lysine methylation (GO:0034968)2.74045483
64nucleus localization (GO:0051647)2.73299855
65cerebral cortex development (GO:0021987)2.73244118
66negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.71812179
67negative regulation of translation, ncRNA-mediated (GO:0040033)2.71812179
68regulation of translation, ncRNA-mediated (GO:0045974)2.71812179
69centriole replication (GO:0007099)2.70570262
70granulocyte differentiation (GO:0030851)2.67022349
713-UTR-mediated mRNA stabilization (GO:0070935)2.66225022
72regulation of DNA damage checkpoint (GO:2000001)2.65673349
73regulation of spindle organization (GO:0090224)2.63607995
74negative regulation of cell cycle G2/M phase transition (GO:1902750)2.63422287
75central nervous system neuron axonogenesis (GO:0021955)2.63304637
76lymph vessel development (GO:0001945)2.62069245
77nucleobase catabolic process (GO:0046113)2.61980477
78regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.60573187
79regulation of developmental pigmentation (GO:0048070)2.59600776
80regulation of NFAT protein import into nucleus (GO:0051532)2.59300683
81dendritic spine morphogenesis (GO:0060997)2.57487335
82T cell lineage commitment (GO:0002360)2.57385218
83positive regulation of mitotic sister chromatid separation (GO:1901970)2.56574682
84positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.56574682
85positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.56574682
86social behavior (GO:0035176)2.55237179
87intraspecies interaction between organisms (GO:0051703)2.55237179
88embryonic retina morphogenesis in camera-type eye (GO:0060059)2.55223605
89forebrain neuron differentiation (GO:0021879)2.54123601
90positive regulation of actin cytoskeleton reorganization (GO:2000251)2.53185549
91organelle transport along microtubule (GO:0072384)2.52636137
92post-anal tail morphogenesis (GO:0036342)2.52312778
93lymphangiogenesis (GO:0001946)2.52255346
94membrane assembly (GO:0071709)2.50580868
95positive regulation of granulocyte differentiation (GO:0030854)2.50084592
96mRNA splice site selection (GO:0006376)2.46410022
97histone mRNA catabolic process (GO:0071044)2.46382243
98protein demethylation (GO:0006482)2.44487173
99protein dealkylation (GO:0008214)2.44487173
100cell proliferation in forebrain (GO:0021846)2.43368070

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.77039615
2CEBPD_23245923_ChIP-Seq_MEFs_Mouse3.12056510
3TAF15_26573619_Chip-Seq_HEK293_Human3.07446788
4GBX2_23144817_ChIP-Seq_PC3_Human2.93088584
5FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.86295353
6HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse2.77132420
7IGF1R_20145208_ChIP-Seq_DFB_Human2.72433762
8SMARCD1_25818293_ChIP-Seq_ESCs_Mouse2.51152470
9E2F7_22180533_ChIP-Seq_HELA_Human2.48182663
10BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse2.47280397
11POU3F2_20337985_ChIP-ChIP_501MEL_Human2.45490220
12VDR_22108803_ChIP-Seq_LS180_Human2.31327965
13POU5F1_26923725_Chip-Seq_MESODERM_Mouse2.31226399
14TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.31226399
15FUS_26573619_Chip-Seq_HEK293_Human2.13882438
16STAT6_21828071_ChIP-Seq_BEAS2B_Human2.03026227
17SALL1_21062744_ChIP-ChIP_HESCs_Human2.01017748
18AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.98761184
19PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.98143554
20MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.96540477
21SMAD4_21799915_ChIP-Seq_A2780_Human1.96308497
22OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.88960895
23GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.86796148
24KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.84031338
25ZFP57_27257070_Chip-Seq_ESCs_Mouse1.77878513
26SMAD_19615063_ChIP-ChIP_OVARY_Human1.77374512
27TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.72836312
28STAT3_23295773_ChIP-Seq_U87_Human1.71358945
29TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.69873659
30NANOG_18555785_Chip-Seq_ESCs_Mouse1.69406012
31FLI1_27457419_Chip-Seq_LIVER_Mouse1.69191424
32PCGF2_27294783_Chip-Seq_NPCs_Mouse1.68988096
33SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.66482038
34EWS_26573619_Chip-Seq_HEK293_Human1.63984122
35TP53_16413492_ChIP-PET_HCT116_Human1.60337914
36P300_19829295_ChIP-Seq_ESCs_Human1.59275477
37GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.56225158
38BCAT_22108803_ChIP-Seq_LS180_Human1.53011692
39AR_21572438_ChIP-Seq_LNCaP_Human1.46692067
40E2F1_18555785_Chip-Seq_ESCs_Mouse1.46656475
41PCGF2_27294783_Chip-Seq_ESCs_Mouse1.45116617
42ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.43247906
43TCF4_23295773_ChIP-Seq_U87_Human1.42784256
44EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.41649600
45IRF1_19129219_ChIP-ChIP_H3396_Human1.38405949
46CTBP2_25329375_ChIP-Seq_LNCAP_Human1.38243086
47P53_22387025_ChIP-Seq_ESCs_Mouse1.37520070
48CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.37327538
49GF1B_26923725_Chip-Seq_HPCs_Mouse1.36715719
50SUZ12_27294783_Chip-Seq_NPCs_Mouse1.35914389
51TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.33893053
52TP63_19390658_ChIP-ChIP_HaCaT_Human1.31956157
53TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.30817016
54SMAD3_21741376_ChIP-Seq_EPCs_Human1.28626169
55CMYC_18555785_Chip-Seq_ESCs_Mouse1.27679468
56FOXM1_23109430_ChIP-Seq_U2OS_Human1.27339961
57MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.25979760
58UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.25316343
59SCL_19346495_ChIP-Seq_HPC-7_Human1.24827722
60TOP2B_26459242_ChIP-Seq_MCF-7_Human1.22096655
61E2F4_17652178_ChIP-ChIP_JURKAT_Human1.20526125
62ZNF217_24962896_ChIP-Seq_MCF-7_Human1.20514119
63RXR_22108803_ChIP-Seq_LS180_Human1.19946936
64CTBP1_25329375_ChIP-Seq_LNCAP_Human1.19192080
65NFE2_27457419_Chip-Seq_LIVER_Mouse1.19086837
66WT1_19549856_ChIP-ChIP_CCG9911_Human1.19006606
67VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.18197058
68CBX2_27304074_Chip-Seq_ESCs_Mouse1.17055602
69MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.15671159
70EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.14611676
71KDM2B_26808549_Chip-Seq_REH_Human1.14368455
72EZH2_27294783_Chip-Seq_NPCs_Mouse1.14252685
73PIAS1_25552417_ChIP-Seq_VCAP_Human1.13555307
74SUZ12_18555785_Chip-Seq_ESCs_Mouse1.12123965
75RUNX_20019798_ChIP-Seq_JUKART_Human1.10427920
76SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.10211155
77NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.10128821
78RBPJ_22232070_ChIP-Seq_NCS_Mouse1.09118833
79KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.08772376
80LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.07856779
81E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.07140944
82CBP_20019798_ChIP-Seq_JUKART_Human1.06595224
83IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.06595224
84CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.05597681
85STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.05346240
86ZNF274_21170338_ChIP-Seq_K562_Hela1.04062074
87RNF2_27304074_Chip-Seq_NSC_Mouse1.03608636
88ER_23166858_ChIP-Seq_MCF-7_Human1.03481286
89NMYC_18555785_Chip-Seq_ESCs_Mouse1.03082462
90STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.02931226
91STAT3_18555785_Chip-Seq_ESCs_Mouse1.00802481
92OCT4_18555785_Chip-Seq_ESCs_Mouse0.99841387
93SOX2_21211035_ChIP-Seq_LN229_Gbm0.99645877
94TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.98945243
95FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.98117318
96YAP1_20516196_ChIP-Seq_MESCs_Mouse0.97869308
97NR3C1_23031785_ChIP-Seq_PC12_Mouse0.96872096
98ARNT_22903824_ChIP-Seq_MCF-7_Human0.96804128
99FLI1_21867929_ChIP-Seq_TH2_Mouse0.95860896
100FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.95367124

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000569_abnormal_digit_pigmentation6.21795709
2MP0008057_abnormal_DNA_replication5.17696406
3MP0005187_abnormal_penis_morphology3.98545049
4MP0002638_abnormal_pupillary_reflex3.50662298
5MP0005174_abnormal_tail_pigmentation3.27712074
6MP0000015_abnormal_ear_pigmentation3.12172927
7MP0003880_abnormal_central_pattern3.07864966
8MP0008995_early_reproductive_senescence2.74305714
9MP0010368_abnormal_lymphatic_system2.61824684
10MP0001968_abnormal_touch/_nociception2.51693175
11MP0002102_abnormal_ear_morphology2.38291867
12MP0000778_abnormal_nervous_system2.37205617
13MP0006276_abnormal_autonomic_nervous2.26814585
14MP0003656_abnormal_erythrocyte_physiolo2.25055859
15MP0001177_atelectasis2.16260143
16MP0003787_abnormal_imprinting2.11439103
17MP0003172_abnormal_lysosome_physiology1.96280102
18MP0002095_abnormal_skin_pigmentation1.95369443
19MP0005409_darkened_coat_color1.83079277
20MP0000647_abnormal_sebaceous_gland1.72849741
21MP0010386_abnormal_urinary_bladder1.64228107
22MP0003121_genomic_imprinting1.50121732
23MP0001188_hyperpigmentation1.42637257
24MP0003221_abnormal_cardiomyocyte_apopto1.41520419
25MP0002295_abnormal_pulmonary_circulatio1.40612601
26MP0000383_abnormal_hair_follicle1.35211839
27MP0008877_abnormal_DNA_methylation1.29573252
28MP0003693_abnormal_embryo_hatching1.25094372
29MP0002735_abnormal_chemical_nociception1.21638569
30MP0005645_abnormal_hypothalamus_physiol1.20120507
31MP0003045_fibrosis1.19645102
32MP0003890_abnormal_embryonic-extraembry1.15505455
33MP0001727_abnormal_embryo_implantation1.13816481
34MP0003635_abnormal_synaptic_transmissio1.11314272
35MP0004883_abnormal_blood_vessel1.11068897
36MP0002177_abnormal_outer_ear1.10258123
37MP0001293_anophthalmia1.10088883
38MP0004859_abnormal_synaptic_plasticity1.09968998
39MP0002184_abnormal_innervation1.09263274
40MP0003115_abnormal_respiratory_system1.08610140
41MP0004924_abnormal_behavior1.07847682
42MP0005386_behavior/neurological_phenoty1.07847682
43MP0002736_abnormal_nociception_after1.05857248
44MP0003763_abnormal_thymus_physiology1.05252868
45MP0002751_abnormal_autonomic_nervous1.04797908
46MP0000427_abnormal_hair_cycle1.02933076
47MP0001529_abnormal_vocalization1.02789036
48MP0010094_abnormal_chromosome_stability1.02717456
49MP0003111_abnormal_nucleus_morphology1.01573953
50MP0002084_abnormal_developmental_patter0.99961074
51MP0003861_abnormal_nervous_system0.98474501
52MP0002063_abnormal_learning/memory/cond0.97219697
53MP0000955_abnormal_spinal_cord0.96978184
54MP0002067_abnormal_sensory_capabilities0.95605970
55MP0004130_abnormal_muscle_cell0.94442924
56MP0001879_abnormal_lymphatic_vessel0.93177933
57MP0003122_maternal_imprinting0.90720858
58MP0008058_abnormal_DNA_repair0.90622675
59MP0003786_premature_aging0.90178172
60MP0002081_perinatal_lethality0.88605817
61MP0000465_gastrointestinal_hemorrhage0.87879335
62MP0009703_decreased_birth_body0.87856271
63MP0003935_abnormal_craniofacial_develop0.87163934
64MP0004270_analgesia0.85678594
65MP0000371_diluted_coat_color0.85412514
66MP0003950_abnormal_plasma_membrane0.85084697
67MP0004381_abnormal_hair_follicle0.84645503
68MP0001286_abnormal_eye_development0.82887569
69MP0000013_abnormal_adipose_tissue0.82632913
70MP0003077_abnormal_cell_cycle0.82582748
71MP0003011_delayed_dark_adaptation0.82407629
72MP0002733_abnormal_thermal_nociception0.82304232
73MP0002152_abnormal_brain_morphology0.81865953
74MP0003632_abnormal_nervous_system0.81370833
75MP0002163_abnormal_gland_morphology0.79065323
76MP0002882_abnormal_neuron_morphology0.77493104
77MP0001756_abnormal_urination0.74912854
78MP0002009_preneoplasia0.73184546
79MP0000428_abnormal_craniofacial_morphol0.72524553
80MP0005388_respiratory_system_phenotype0.72103272
81MP0002133_abnormal_respiratory_system0.72103272
82MP0004885_abnormal_endolymph0.70753895
83MP0003091_abnormal_cell_migration0.70110286
84MP0004811_abnormal_neuron_physiology0.64603034
85MP0002086_abnormal_extraembryonic_tissu0.64292878
86MP0010678_abnormal_skin_adnexa0.62992240
87MP0001661_extended_life_span0.62624673
88MP0001697_abnormal_embryo_size0.62564085
89MP0003878_abnormal_ear_physiology0.62514256
90MP0005377_hearing/vestibular/ear_phenot0.62514256
91MP0001730_embryonic_growth_arrest0.60855606
92MP0001486_abnormal_startle_reflex0.59717935
93MP0001915_intracranial_hemorrhage0.59586049
94MP0001943_abnormal_respiration0.59437361
95MP0001119_abnormal_female_reproductive0.58653328
96MP0002272_abnormal_nervous_system0.58444533
97MP0005075_abnormal_melanosome_morpholog0.57729553
98MP0001672_abnormal_embryogenesis/_devel0.57063000
99MP0005380_embryogenesis_phenotype0.57063000
100MP0002127_abnormal_cardiovascular_syste0.56020661

Predicted human phenotypes

RankGene SetZ-score
1Large earlobe (HP:0009748)5.07964191
2Vertebral arch anomaly (HP:0008438)4.54788244
3Hepatoblastoma (HP:0002884)4.39844155
4Curly hair (HP:0002212)4.25232421
5Overgrowth (HP:0001548)4.00446514
6Drooling (HP:0002307)3.97559220
7Papillary thyroid carcinoma (HP:0002895)3.88399411
8Cortical dysplasia (HP:0002539)3.82436808
9Excessive salivation (HP:0003781)3.70683481
10Rhabdomyosarcoma (HP:0002859)3.58945494
11Medulloblastoma (HP:0002885)3.25826281
12Diastasis recti (HP:0001540)3.21195758
13Hyperventilation (HP:0002883)3.16412935
14Concave nail (HP:0001598)3.16364815
15Barrel-shaped chest (HP:0001552)3.15278877
16Volvulus (HP:0002580)3.09996697
17Neoplasm of the adrenal cortex (HP:0100641)3.08166698
18Megalencephaly (HP:0001355)3.07848182
19Papilledema (HP:0001085)2.98477626
20Obstructive sleep apnea (HP:0002870)2.92488526
21Neoplasm of striated muscle (HP:0009728)2.85527800
22Deep palmar crease (HP:0006191)2.75638930
23Tented upper lip vermilion (HP:0010804)2.70704183
24Limb hypertonia (HP:0002509)2.69904548
25Hypophosphatemic rickets (HP:0004912)2.69475513
26Long clavicles (HP:0000890)2.56317672
27Thyroid carcinoma (HP:0002890)2.53790498
28Deep philtrum (HP:0002002)2.53339404
29Protruding tongue (HP:0010808)2.45976129
30Acute myeloid leukemia (HP:0004808)2.32279322
31Bladder carcinoma (HP:0002862)2.30906699
32Bladder neoplasm (HP:0009725)2.30906699
33Abnormality of salivation (HP:0100755)2.24092366
34Abnormal number of incisors (HP:0011064)2.21728093
35Pulmonic stenosis (HP:0001642)2.21663777
36Submucous cleft hard palate (HP:0000176)2.20156689
37Partial agenesis of the corpus callosum (HP:0001338)2.15600172
38Pointed chin (HP:0000307)2.13034318
39Broad-based gait (HP:0002136)2.11225108
40Thoracolumbar scoliosis (HP:0002944)2.07014784
41Abnormality of the intervertebral disk (HP:0005108)2.06091655
42Myelomeningocele (HP:0002475)2.05994954
43Basal cell carcinoma (HP:0002671)1.97841617
44Anomalous pulmonary venous return (HP:0010772)1.97355768
45Rib fusion (HP:0000902)1.95433724
46Hypochromic microcytic anemia (HP:0004840)1.93623749
47Bronchomalacia (HP:0002780)1.92827789
48Neonatal hypoglycemia (HP:0001998)1.92341861
49Sex reversal (HP:0012245)1.92001068
50Abnormal sex determination (HP:0012244)1.92001068
51Widely spaced teeth (HP:0000687)1.91726604
52Abnormality of the axillary hair (HP:0100134)1.91554245
53Abnormality of secondary sexual hair (HP:0009888)1.91554245
54Prominent occiput (HP:0000269)1.90875619
55Porencephaly (HP:0002132)1.89557026
56Abnormality of the incisor (HP:0000676)1.86337183
57Macroglossia (HP:0000158)1.83490308
58Severe combined immunodeficiency (HP:0004430)1.82697737
59Tracheomalacia (HP:0002779)1.82063823
60Gingival bleeding (HP:0000225)1.77427264
61Hypoplastic labia majora (HP:0000059)1.76881266
62High anterior hairline (HP:0009890)1.75799337
63Sudden death (HP:0001699)1.75154102
64T lymphocytopenia (HP:0005403)1.74552056
65Hypoplastic toenails (HP:0001800)1.74161098
66Supernumerary ribs (HP:0005815)1.74011761
67Absent speech (HP:0001344)1.72533709
68Capillary hemangiomas (HP:0005306)1.72295958
69Aplasia/Hypoplasia of the sternum (HP:0006714)1.71616935
70Abnormality of the odontoid process (HP:0003310)1.71601945
71Obsessive-compulsive behavior (HP:0000722)1.71411997
72Sensorimotor neuropathy (HP:0007141)1.71352739
73Exotropia (HP:0000577)1.71216611
74Short 4th metacarpal (HP:0010044)1.70072085
75Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.70072085
76Abnormality of the antihelix (HP:0009738)1.68831427
77Neoplasm of the tracheobronchial system (HP:0100552)1.68802536
78Abnormality of the vasculature of the conjunctiva (HP:0008054)1.68451137
79Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.68341524
80Truncal obesity (HP:0001956)1.67428583
81Abnormality of the labia majora (HP:0012881)1.66407772
82Abnormality of the astrocytes (HP:0100707)1.66139405
83Astrocytoma (HP:0009592)1.66139405
84Arnold-Chiari malformation (HP:0002308)1.66028691
85Hypoplastic iliac wings (HP:0002866)1.65938743
86Tapered finger (HP:0001182)1.64418762
87Slow saccadic eye movements (HP:0000514)1.64046755
88Fair hair (HP:0002286)1.62607335
89Abnormality of abdominal situs (HP:0011620)1.61970312
90Abdominal situs inversus (HP:0003363)1.61970312
91Spina bifida occulta (HP:0003298)1.61509254
92Achilles tendon contracture (HP:0001771)1.61373637
93Absent frontal sinuses (HP:0002688)1.60853012
94Lower limb hyperreflexia (HP:0002395)1.60777215
95Infantile muscular hypotonia (HP:0008947)1.60566966
96Vertebral fusion (HP:0002948)1.59884275
97Macroorchidism (HP:0000053)1.59001683
98Autoamputation (HP:0001218)1.56230916
99Heterotopia (HP:0002282)1.55162064
100Arthropathy (HP:0003040)1.55055180

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK4.81606736
2KDR3.84188751
3MAP3K42.88985861
4BLK2.88955293
5BRD42.85824369
6TNIK2.70189479
7CDK122.55276966
8MAP2K72.38330671
9IRAK22.30775750
10NTRK32.22819113
11MAP3K102.01494887
12MARK11.86151746
13FRK1.83449865
14MAP3K21.81890262
15CDC71.78505996
16SGK21.77682019
17WNK31.77387151
18CAMK1G1.70126687
19PNCK1.61320508
20WNK11.43192575
21STK41.41687458
22AKT31.37206437
23CDK31.34110660
24YES11.26406152
25NTRK21.26333746
26MKNK21.22250820
27NEK61.16573957
28SCYL21.11413497
29CAMK1D1.08489593
30SGK31.06854800
31SYK1.05045520
32MAPK131.04912923
33MARK21.04532765
34PDGFRB0.98496149
35SGK4940.94294640
36SGK2230.94294640
37MKNK10.93377564
38TYRO30.92963296
39HIPK20.90512090
40TEC0.88345165
41PLK20.86501542
42ATR0.84746047
43BTK0.83613919
44MAP4K20.83238723
45NUAK10.81261801
46PAK30.80247665
47FGR0.78419060
48STK38L0.77892168
49ATM0.75391730
50GRK60.74741862
51PLK30.72107012
52BMX0.71306612
53PINK10.69476332
54CSNK1D0.69020394
55RPS6KA40.68994120
56BCR0.68651342
57DYRK1A0.67646521
58CDK60.65862999
59MAP2K40.63936781
60TXK0.63922023
61BRSK20.63127158
62KSR10.59273768
63CSK0.59256538
64CCNB10.58973241
65PLK40.57686397
66WNK40.55298957
67BMPR1B0.55057033
68FES0.54398691
69MTOR0.54302059
70LYN0.54095133
71INSRR0.53758799
72PLK10.53595167
73CHEK10.51873388
74RAF10.51100014
75RPS6KB10.49468155
76CLK10.44306677
77CDK10.41235798
78MARK30.41075460
79SRPK10.40915928
80PTK2B0.40906674
81NME10.40340325
82PRKG10.39381219
83STK100.39267280
84FYN0.38976824
85CDK20.38389246
86CSNK1E0.37308267
87EGFR0.37247283
88PIM10.37193926
89SGK10.36630950
90FGFR30.36454220
91IKBKE0.35861331
92ERBB30.35556176
93GSK3B0.35381615
94IRAK40.35338049
95CDK40.35262458
96LCK0.35019639
97CDK90.34181214
98ERBB20.33315574
99RET0.32612253
100NTRK10.30726519

Predicted pathways (KEGG)

RankGene SetZ-score
1Endometrial cancer_Homo sapiens_hsa052132.21810213
2Non-small cell lung cancer_Homo sapiens_hsa052232.20067361
3Non-homologous end-joining_Homo sapiens_hsa034501.91410233
4B cell receptor signaling pathway_Homo sapiens_hsa046621.84345351
5Renal cell carcinoma_Homo sapiens_hsa052111.82114143
6T cell receptor signaling pathway_Homo sapiens_hsa046601.81600724
7Lysine degradation_Homo sapiens_hsa003101.76893700
8Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.71508252
9Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.68652857
10Colorectal cancer_Homo sapiens_hsa052101.63379234
11Vitamin B6 metabolism_Homo sapiens_hsa007501.59309547
12Nicotine addiction_Homo sapiens_hsa050331.58236731
13Chronic myeloid leukemia_Homo sapiens_hsa052201.57320649
14Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.57137367
15ErbB signaling pathway_Homo sapiens_hsa040121.56475372
16Prolactin signaling pathway_Homo sapiens_hsa049171.50938657
17Gap junction_Homo sapiens_hsa045401.50052890
18Circadian rhythm_Homo sapiens_hsa047101.44307914
19Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.40525701
20FoxO signaling pathway_Homo sapiens_hsa040681.40038009
21Glioma_Homo sapiens_hsa052141.38698331
22Adherens junction_Homo sapiens_hsa045201.38251015
23Cholinergic synapse_Homo sapiens_hsa047251.36365970
24Estrogen signaling pathway_Homo sapiens_hsa049151.35245100
25MicroRNAs in cancer_Homo sapiens_hsa052061.34529938
26Phosphatidylinositol signaling system_Homo sapiens_hsa040701.33184003
27Prostate cancer_Homo sapiens_hsa052151.32122053
28Platelet activation_Homo sapiens_hsa046111.31763960
29Thyroid cancer_Homo sapiens_hsa052161.31496576
30Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.29868999
31Thyroid hormone signaling pathway_Homo sapiens_hsa049191.27859693
32Inositol phosphate metabolism_Homo sapiens_hsa005621.27405699
33Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.24320945
34Long-term potentiation_Homo sapiens_hsa047201.19402119
35Acute myeloid leukemia_Homo sapiens_hsa052211.10549385
36Taste transduction_Homo sapiens_hsa047421.09866544
37Long-term depression_Homo sapiens_hsa047301.09350647
38Choline metabolism in cancer_Homo sapiens_hsa052311.09168507
39Neurotrophin signaling pathway_Homo sapiens_hsa047221.07632378
40Glutamatergic synapse_Homo sapiens_hsa047241.00491109
41Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.00025375
42Axon guidance_Homo sapiens_hsa043600.99393535
43Cell cycle_Homo sapiens_hsa041100.99045274
44Pancreatic cancer_Homo sapiens_hsa052120.99043891
45GABAergic synapse_Homo sapiens_hsa047270.97509848
46Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.97426116
47Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.95659567
48Sphingolipid signaling pathway_Homo sapiens_hsa040710.95124785
49Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.94972836
50GnRH signaling pathway_Homo sapiens_hsa049120.93205676
51Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.92976588
52Longevity regulating pathway - mammal_Homo sapiens_hsa042110.92661084
53Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.90748574
54mRNA surveillance pathway_Homo sapiens_hsa030150.89965326
55Jak-STAT signaling pathway_Homo sapiens_hsa046300.87290406
56Dorso-ventral axis formation_Homo sapiens_hsa043200.85888079
57AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.85458713
58Type II diabetes mellitus_Homo sapiens_hsa049300.84187158
59Focal adhesion_Homo sapiens_hsa045100.84076017
60Ras signaling pathway_Homo sapiens_hsa040140.83254426
61Circadian entrainment_Homo sapiens_hsa047130.83104502
62Rap1 signaling pathway_Homo sapiens_hsa040150.79958927
63Melanoma_Homo sapiens_hsa052180.79553845
64Phospholipase D signaling pathway_Homo sapiens_hsa040720.77510257
65Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.74550127
66Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.73721151
67Hepatitis B_Homo sapiens_hsa051610.72906035
68Steroid biosynthesis_Homo sapiens_hsa001000.72275051
69Morphine addiction_Homo sapiens_hsa050320.72023176
70VEGF signaling pathway_Homo sapiens_hsa043700.71039618
71Primary immunodeficiency_Homo sapiens_hsa053400.70891510
72Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.70111841
73Chemokine signaling pathway_Homo sapiens_hsa040620.69562927
74Melanogenesis_Homo sapiens_hsa049160.68530695
75Serotonergic synapse_Homo sapiens_hsa047260.68525771
76mTOR signaling pathway_Homo sapiens_hsa041500.67389294
77Oocyte meiosis_Homo sapiens_hsa041140.67139517
78cAMP signaling pathway_Homo sapiens_hsa040240.65582379
79TGF-beta signaling pathway_Homo sapiens_hsa043500.65348471
80Spliceosome_Homo sapiens_hsa030400.63695402
81Central carbon metabolism in cancer_Homo sapiens_hsa052300.63607388
82Thyroid hormone synthesis_Homo sapiens_hsa049180.61706116
83Wnt signaling pathway_Homo sapiens_hsa043100.61272955
84Fanconi anemia pathway_Homo sapiens_hsa034600.60984816
85Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.60941035
86Dopaminergic synapse_Homo sapiens_hsa047280.60394298
87Pancreatic secretion_Homo sapiens_hsa049720.57071286
88Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.56731647
89NOD-like receptor signaling pathway_Homo sapiens_hsa046210.54165519
90Proteoglycans in cancer_Homo sapiens_hsa052050.52289170
91Regulation of actin cytoskeleton_Homo sapiens_hsa048100.50963875
92PI3K-Akt signaling pathway_Homo sapiens_hsa041510.50849338
93Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.50033613
94AMPK signaling pathway_Homo sapiens_hsa041520.50020567
95Aldosterone synthesis and secretion_Homo sapiens_hsa049250.48613385
96Hedgehog signaling pathway_Homo sapiens_hsa043400.47127703
97Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.46058185
98cGMP-PKG signaling pathway_Homo sapiens_hsa040220.45363977
99RNA transport_Homo sapiens_hsa030130.45293254
100Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.44906620

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