Rank | Gene Set | Z-score |
---|---|---|
1 | positive regulation by symbiont of host defense response (GO:0052509) | 5.70249823 |
2 | modulation by symbiont of host defense response (GO:0052031) | 5.70249823 |
3 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 5.70249823 |
4 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 5.70249823 |
5 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 5.70249823 |
6 | modulation by symbiont of host immune response (GO:0052553) | 5.70249823 |
7 | response to peptidoglycan (GO:0032494) | 5.51942217 |
8 | regulation of vitamin D biosynthetic process (GO:0060556) | 5.34971550 |
9 | neutrophil activation involved in immune response (GO:0002283) | 5.03811164 |
10 | positive regulation of interferon-alpha production (GO:0032727) | 4.58013370 |
11 | regulation of interferon-alpha production (GO:0032647) | 4.37882353 |
12 | response to muramyl dipeptide (GO:0032495) | 4.29148641 |
13 | macrophage activation involved in immune response (GO:0002281) | 4.21322679 |
14 | regulation of podosome assembly (GO:0071801) | 4.19374301 |
15 | positive regulation of chemokine biosynthetic process (GO:0045080) | 4.15448248 |
16 | regulation of cytokine secretion involved in immune response (GO:0002739) | 4.12907857 |
17 | regulation of vitamin metabolic process (GO:0030656) | 4.09961805 |
18 | response to host immune response (GO:0052572) | 4.09019137 |
19 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 4.09019137 |
20 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 4.08712896 |
21 | regulation of T-helper 1 cell differentiation (GO:0045625) | 4.06912657 |
22 | positive regulation of heat generation (GO:0031652) | 3.98557277 |
23 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 3.97282777 |
24 | respiratory burst (GO:0045730) | 3.94687019 |
25 | positive regulation of cellular amide metabolic process (GO:0034250) | 3.94104726 |
26 | natural killer cell mediated cytotoxicity (GO:0042267) | 3.92836989 |
27 | natural killer cell mediated immunity (GO:0002228) | 3.92836989 |
28 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 3.89064298 |
29 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.89015603 |
30 | granulocyte activation (GO:0036230) | 3.87579113 |
31 | NIK/NF-kappaB signaling (GO:0038061) | 3.83704595 |
32 | immunoglobulin mediated immune response (GO:0016064) | 3.83045974 |
33 | response to protozoan (GO:0001562) | 3.82342833 |
34 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.80758786 |
35 | cellular response to type I interferon (GO:0071357) | 3.80179881 |
36 | type I interferon signaling pathway (GO:0060337) | 3.80179881 |
37 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 3.77907812 |
38 | hydrogen peroxide biosynthetic process (GO:0050665) | 3.75165694 |
39 | response to type I interferon (GO:0034340) | 3.74047062 |
40 | positive regulation of antigen processing and presentation (GO:0002579) | 3.73883090 |
41 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.73554529 |
42 | regulation of activation of Janus kinase activity (GO:0010533) | 3.71557586 |
43 | superoxide anion generation (GO:0042554) | 3.71226550 |
44 | positive regulation of interleukin-12 production (GO:0032735) | 3.65967053 |
45 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 3.65670006 |
46 | negative regulation of interleukin-17 production (GO:0032700) | 3.64881426 |
47 | regulation of fever generation (GO:0031620) | 3.64179572 |
48 | neutrophil activation (GO:0042119) | 3.62995521 |
49 | response to host (GO:0075136) | 3.58024416 |
50 | response to host defenses (GO:0052200) | 3.58024416 |
51 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.58024416 |
52 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 3.55033719 |
53 | negative regulation of cytokine production involved in immune response (GO:0002719) | 3.52294463 |
54 | cellular response to interferon-beta (GO:0035458) | 3.51175518 |
55 | positive regulation of membrane protein ectodomain proteolysis (GO:0051044) | 3.50977227 |
56 | positive regulation of NF-kappaB import into nucleus (GO:0042346) | 3.47000025 |
57 | interferon-gamma-mediated signaling pathway (GO:0060333) | 3.44773677 |
58 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.44294391 |
59 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 3.40421096 |
60 | myeloid dendritic cell differentiation (GO:0043011) | 3.40182471 |
61 | T-helper 1 type immune response (GO:0042088) | 3.39583736 |
62 | negative regulation of viral genome replication (GO:0045071) | 3.38985500 |
63 | regulation of chemokine biosynthetic process (GO:0045073) | 3.37985671 |
64 | microglial cell activation (GO:0001774) | 3.37642262 |
65 | myeloid cell activation involved in immune response (GO:0002275) | 3.36277719 |
66 | defense response to protozoan (GO:0042832) | 3.33251092 |
67 | negative regulation of cell killing (GO:0031342) | 3.30910917 |
68 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 3.30910917 |
69 | reactive oxygen species biosynthetic process (GO:1903409) | 3.30475856 |
70 | regulation of interleukin-17 production (GO:0032660) | 3.27992624 |
71 | positive regulation of interferon-beta production (GO:0032728) | 3.27569043 |
72 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 3.25995416 |
73 | positive regulation of type 2 immune response (GO:0002830) | 3.25901727 |
74 | neutrophil mediated immunity (GO:0002446) | 3.25728188 |
75 | regulation of membrane protein ectodomain proteolysis (GO:0051043) | 3.24002701 |
76 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 3.21877402 |
77 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.21877402 |
78 | leukocyte mediated cytotoxicity (GO:0001909) | 3.21832995 |
79 | cellular response to lipopolysaccharide (GO:0071222) | 3.21472066 |
80 | positive regulation of interleukin-17 production (GO:0032740) | 3.20873780 |
81 | phagosome maturation (GO:0090382) | 3.20345040 |
82 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 3.19095882 |
83 | positive regulation of mast cell degranulation (GO:0043306) | 3.19095882 |
84 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 3.17257453 |
85 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.16372694 |
86 | cellular response to molecule of bacterial origin (GO:0071219) | 3.13061081 |
87 | regulation of chronic inflammatory response (GO:0002676) | 3.12080969 |
88 | negative regulation of myeloid cell apoptotic process (GO:0033033) | 3.11393194 |
89 | regulation of antigen processing and presentation (GO:0002577) | 3.10715680 |
90 | regulation of syncytium formation by plasma membrane fusion (GO:0060142) | 3.10624434 |
91 | regulation of interleukin-12 production (GO:0032655) | 3.09761447 |
92 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 3.09333339 |
93 | regulation of interferon-gamma biosynthetic process (GO:0045072) | 3.07667258 |
94 | modulation by symbiont of host cellular process (GO:0044068) | 3.07577666 |
95 | regulation of mast cell degranulation (GO:0043304) | 3.07156980 |
96 | myeloid dendritic cell activation (GO:0001773) | 3.06718446 |
97 | regulation of immunoglobulin secretion (GO:0051023) | 3.05804687 |
98 | positive regulation of interferon-gamma biosynthetic process (GO:0045078) | 3.05284111 |
99 | negative regulation of interleukin-12 production (GO:0032695) | 3.04037540 |
100 | regulation of T-helper 2 cell differentiation (GO:0045628) | 3.02318470 |
101 | positive regulation of mast cell activation (GO:0033005) | 3.01845633 |
102 | I-kappaB phosphorylation (GO:0007252) | 2.99231106 |
103 | lymphocyte chemotaxis (GO:0048247) | 2.96623825 |
104 | positive regulation of interleukin-1 beta secretion (GO:0050718) | 2.96601268 |
105 | positive regulation of syncytium formation by plasma membrane fusion (GO:0060143) | 2.96098701 |
106 | positive regulation of T-helper cell differentiation (GO:0045624) | 2.95457508 |
107 | negative regulation of nitric oxide biosynthetic process (GO:0045019) | 2.95352411 |
108 | regulation of mononuclear cell migration (GO:0071675) | 2.95229842 |
109 | negative regulation of toll-like receptor 4 signaling pathway (GO:0034144) | 2.94800199 |
110 | germinal center formation (GO:0002467) | 2.94388656 |
111 | cellular response to exogenous dsRNA (GO:0071360) | 2.94303019 |
112 | positive regulation of interleukin-10 production (GO:0032733) | 2.94291036 |
113 | dendritic cell differentiation (GO:0097028) | 2.93728969 |
114 | macrophage activation (GO:0042116) | 2.93547482 |
115 | eosinophil chemotaxis (GO:0048245) | 2.93520766 |
116 | cellular response to interferon-gamma (GO:0071346) | 2.93445223 |
117 | positive regulation of humoral immune response (GO:0002922) | 2.92837287 |
118 | B cell mediated immunity (GO:0019724) | 2.92434306 |
119 | response to interferon-beta (GO:0035456) | 2.91885592 |
120 | branching involved in labyrinthine layer morphogenesis (GO:0060670) | 2.90931425 |
121 | glycosphingolipid catabolic process (GO:0046479) | 2.90929569 |
122 | positive regulation of interleukin-6 production (GO:0032755) | 2.90427377 |
123 | positive regulation of heterotypic cell-cell adhesion (GO:0034116) | 2.89248937 |
124 | regulation of nitric oxide biosynthetic process (GO:0045428) | 2.88587336 |
125 | positive regulation of nitric oxide biosynthetic process (GO:0045429) | 2.86008545 |
126 | negative regulation of inflammatory response to antigenic stimulus (GO:0002862) | 2.85745672 |
127 | monocyte chemotaxis (GO:0002548) | 2.85721820 |
128 | regulation of heat generation (GO:0031650) | 2.85151854 |
129 | regulation of mast cell activation involved in immune response (GO:0033006) | 2.85088108 |
130 | regulation of type I interferon-mediated signaling pathway (GO:0060338) | 2.84552785 |
131 | regulation of NF-kappaB import into nucleus (GO:0042345) | 2.83742338 |
132 | regulation of type 2 immune response (GO:0002828) | 2.83658037 |
133 | positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372) | 2.83308024 |
134 | detection of other organism (GO:0098543) | 2.82717307 |
135 | positive regulation of acute inflammatory response (GO:0002675) | 2.81016787 |
136 | response to interferon-gamma (GO:0034341) | 2.78988405 |
137 | negative regulation of production of molecular mediator of immune response (GO:0002701) | 2.78599005 |
138 | detection of molecule of bacterial origin (GO:0032490) | 2.77586015 |
139 | T cell migration (GO:0072678) | 2.76332043 |
140 | regulation of interleukin-8 biosynthetic process (GO:0045414) | 2.76085903 |
141 | activation of MAPKKK activity (GO:0000185) | 2.75829836 |
142 | regulation of T-helper cell differentiation (GO:0045622) | 2.73941324 |
143 | regulation of T cell tolerance induction (GO:0002664) | 2.73636844 |
144 | cellular response to biotic stimulus (GO:0071216) | 2.72016624 |
Rank | Gene Set | Z-score |
---|---|---|
1 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 7.43587541 |
2 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 7.24986031 |
3 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 6.98520387 |
4 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 4.85304956 |
5 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 4.38672258 |
6 | * IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 4.07831311 |
7 | * SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.95042913 |
8 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 3.76652023 |
9 | * NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.45356486 |
10 | * RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 3.18044979 |
11 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.94640628 |
12 | * MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.90944721 |
13 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.85044251 |
14 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.74399853 |
15 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.66683794 |
16 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.42691041 |
17 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.31591098 |
18 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.28466368 |
19 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 2.12069945 |
20 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.95211937 |
21 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.90582055 |
22 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.87646257 |
23 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.86669424 |
24 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.84694632 |
25 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.73675839 |
26 | SPI1_23127762_ChIP-Seq_K562_Human | 1.72491918 |
27 | MYC_22102868_ChIP-Seq_BL_Human | 1.71457644 |
28 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.67461582 |
29 | * BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.66954451 |
30 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.66165693 |
31 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.63756424 |
32 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.63483678 |
33 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.61778739 |
34 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.53044145 |
35 | * PU_27001747_Chip-Seq_BMDM_Mouse | 1.50487545 |
36 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.50320745 |
37 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.47115613 |
38 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.45001032 |
39 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.43218600 |
40 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.42108800 |
41 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.42032904 |
42 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.38423971 |
43 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.34040427 |
44 | MYB_26560356_Chip-Seq_TH2_Human | 1.27874898 |
45 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.26833798 |
46 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.26502509 |
47 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.25697661 |
48 | * RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.24521364 |
49 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.22947134 |
50 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.21897913 |
51 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.19605606 |
52 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.18022603 |
53 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.17975583 |
54 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.17294033 |
55 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.16114847 |
56 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.15975785 |
57 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.15905807 |
58 | BCOR_27268052_Chip-Seq_Bcells_Human | 1.15738774 |
59 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.15197096 |
60 | MAF_26560356_Chip-Seq_TH1_Human | 1.14714983 |
61 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.13657750 |
62 | * GATA3_26560356_Chip-Seq_TH2_Human | 1.09851614 |
63 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 1.09482832 |
64 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.07324189 |
65 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 1.07041757 |
66 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.07014914 |
67 | EGR1_19032775_ChIP-ChIP_M12_Human | 1.06647122 |
68 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 1.05847916 |
69 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.01924356 |
70 | KDM2B_26808549_Chip-Seq_K562_Human | 1.01883318 |
71 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.01557678 |
72 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.00271453 |
73 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.99583211 |
74 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.99404797 |
75 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.99265746 |
76 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.98944183 |
77 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 0.98918793 |
78 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.98564015 |
79 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.97283473 |
80 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.96685759 |
81 | MYB_26560356_Chip-Seq_TH1_Human | 0.95854322 |
82 | * GATA3_27048872_Chip-Seq_THYMUS_Human | 0.95767260 |
83 | RACK7_27058665_Chip-Seq_MCF-7_Human | 0.95518932 |
84 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.95472007 |
85 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 0.93894239 |
86 | GATA1_19941826_ChIP-Seq_K562_Human | 0.92871213 |
87 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 0.92353103 |
88 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 0.92353103 |
89 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 0.92009007 |
90 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.90692790 |
91 | GATA1_22025678_ChIP-Seq_K562_Human | 0.90477870 |
92 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 0.90242941 |
93 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.85612439 |
94 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 0.85353936 |
95 | * GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.85150897 |
96 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.84605776 |
97 | VDR_21846776_ChIP-Seq_THP-1_Human | 0.83884323 |
98 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 0.82317391 |
99 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 0.82249700 |
100 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.79433395 |
101 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.78978344 |
102 | * GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.77159953 |
103 | * GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.73374131 |
104 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.73223391 |
105 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 0.72243411 |
106 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 0.72179597 |
107 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.71735666 |
108 | SOX2_20726797_ChIP-Seq_SW620_Human | 0.71300932 |
109 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.69953214 |
110 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 0.69216236 |
111 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.67432304 |
112 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 0.65746001 |
113 | * GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.64847734 |
114 | KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse | 0.64067502 |
115 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 0.63231405 |
116 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.61449945 |
117 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.60844984 |
118 | GATA2_19941826_ChIP-Seq_K562_Human | 0.60634134 |
119 | RXR_22108803_ChIP-Seq_LS180_Human | 0.58544557 |
120 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.57872177 |
121 | * UTX_26944678_Chip-Seq_JUKART_Human | 0.57523310 |
122 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.54120020 |
123 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.54101909 |
124 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 0.53027466 |
125 | CJUN_26792858_Chip-Seq_BT549_Human | 0.51658458 |
126 | MAF_26560356_Chip-Seq_TH2_Human | 0.50997324 |
127 | TCF7_22412390_ChIP-Seq_EML_Mouse | 0.50305387 |
128 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 0.49963455 |
129 | * PU1_27457419_Chip-Seq_LIVER_Mouse | 0.49500536 |
130 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.48694631 |
131 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.47631750 |
132 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 0.47182970 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0001835_abnormal_antigen_presentation | 4.35912238 |
2 | MP0009785_altered_susceptibility_to | 4.03968466 |
3 | MP0003303_peritoneal_inflammation | 3.75077704 |
4 | MP0003436_decreased_susceptibility_to | 3.65432005 |
5 | MP0004510_myositis | 3.59906442 |
6 | MP0002148_abnormal_hypersensitivity_rea | 3.58750144 |
7 | MP0006082_CNS_inflammation | 3.31624196 |
8 | MP0005000_abnormal_immune_tolerance | 3.26693317 |
9 | MP0002419_abnormal_innate_immunity | 3.20386699 |
10 | MP0005025_abnormal_response_to | 3.00658056 |
11 | MP0005387_immune_system_phenotype | 2.98079282 |
12 | MP0001790_abnormal_immune_system | 2.98079282 |
13 | MP0000569_abnormal_digit_pigmentation | 2.86715263 |
14 | MP0000685_abnormal_immune_system | 2.80233454 |
15 | MP0003724_increased_susceptibility_to | 2.65798333 |
16 | MP0002452_abnormal_antigen_presenting | 2.56717848 |
17 | MP0005058_abnormal_lysosome_morphology | 2.53322459 |
18 | MP0005671_abnormal_response_to | 2.49930918 |
19 | MP0001800_abnormal_humoral_immune | 2.49195995 |
20 | MP0002723_abnormal_immune_serum | 2.48582963 |
21 | MP0003172_abnormal_lysosome_physiology | 2.28723206 |
22 | MP0004947_skin_inflammation | 2.25762284 |
23 | MP0009278_abnormal_bone_marrow | 2.25173492 |
24 | MP0002139_abnormal_hepatobiliary_system | 2.20383586 |
25 | MP0001819_abnormal_immune_cell | 2.13578163 |
26 | MP0002420_abnormal_adaptive_immunity | 2.08786702 |
27 | MP0001533_abnormal_skeleton_physiology | 2.00293305 |
28 | MP0005451_abnormal_body_composition | 1.93480031 |
29 | MP0001853_heart_inflammation | 1.91279263 |
30 | MP0009764_decreased_sensitivity_to | 1.90015470 |
31 | MP0003448_altered_tumor_morphology | 1.87132707 |
32 | MP0005464_abnormal_platelet_physiology | 1.85816131 |
33 | MP0004858_abnormal_nervous_system | 1.80371177 |
34 | MP0001845_abnormal_inflammatory_respons | 1.78776914 |
35 | MP0002405_respiratory_system_inflammati | 1.77298860 |
36 | MP0000604_amyloidosis | 1.77020679 |
37 | MP0003075_altered_response_to | 1.75613129 |
38 | MP0005310_abnormal_salivary_gland | 1.73099233 |
39 | MP0003806_abnormal_nucleotide_metabolis | 1.72157897 |
40 | MP0002006_tumorigenesis | 1.63474053 |
41 | MP0008469_abnormal_protein_level | 1.61709433 |
42 | MP0008004_abnormal_stomach_pH | 1.61581702 |
43 | MP0010155_abnormal_intestine_physiology | 1.56328769 |
44 | MP0008260_abnormal_autophagy | 1.52560663 |
45 | MP0006054_spinal_hemorrhage | 1.48386442 |
46 | MP0000343_altered_response_to | 1.48336127 |
47 | MP0000716_abnormal_immune_system | 1.44319563 |
48 | MP0003183_abnormal_peptide_metabolism | 1.38538216 |
49 | MP0005397_hematopoietic_system_phenotyp | 1.36276709 |
50 | MP0001545_abnormal_hematopoietic_system | 1.36276709 |
51 | MP0001501_abnormal_sleep_pattern | 1.35836057 |
52 | MP0002398_abnormal_bone_marrow | 1.32313528 |
53 | MP0002998_abnormal_bone_remodeling | 1.31013100 |
54 | MP0005167_abnormal_blood-brain_barrier | 1.28196799 |
55 | MP0009333_abnormal_splenocyte_physiolog | 1.25979218 |
56 | MP0000858_altered_metastatic_potential | 1.21878435 |
57 | MP0002254_reproductive_system_inflammat | 1.16665361 |
58 | MP0005166_decreased_susceptibility_to | 1.16439811 |
59 | MP0005174_abnormal_tail_pigmentation | 1.13967979 |
60 | MP0002429_abnormal_blood_cell | 1.08593983 |
61 | MP0003690_abnormal_glial_cell | 1.06931368 |
62 | MP0000689_abnormal_spleen_morphology | 1.05055539 |
63 | MP0000015_abnormal_ear_pigmentation | 1.04942218 |
64 | MP0004859_abnormal_synaptic_plasticity | 1.01402734 |
65 | MP0005164_abnormal_response_to | 1.00200907 |
66 | MP0002277_abnormal_respiratory_mucosa | 1.00057722 |
67 | MP0010307_abnormal_tumor_latency | 0.99750814 |
68 | MP0009840_abnormal_foam_cell | 0.98617181 |
69 | MP0003300_gastrointestinal_ulcer | 0.94378915 |
70 | MP0002722_abnormal_immune_system | 0.93325425 |
71 | MP0005076_abnormal_cell_differentiation | 0.90244519 |
72 | MP0002166_altered_tumor_susceptibility | 0.89491290 |
73 | MP0002735_abnormal_chemical_nociception | 0.89035776 |
74 | MP0008874_decreased_physiological_sensi | 0.88630447 |
75 | MP0001663_abnormal_digestive_system | 0.85495179 |
76 | MP0009763_increased_sensitivity_to | 0.85101097 |
77 | MP0009046_muscle_twitch | 0.85035356 |
78 | MP0003091_abnormal_cell_migration | 0.83529770 |
79 | MP0002332_abnormal_exercise_endurance | 0.82692173 |
80 | MP0005390_skeleton_phenotype | 0.82302833 |
81 | MP0010386_abnormal_urinary_bladder | 0.81732576 |
82 | MP0002933_joint_inflammation | 0.80548300 |
83 | MP0001851_eye_inflammation | 0.80060444 |
84 | MP0002138_abnormal_hepatobiliary_system | 0.79898336 |
85 | MP0001542_abnormal_bone_strength | 0.79030048 |
86 | MP0004782_abnormal_surfactant_physiolog | 0.77820118 |
87 | MP0000371_diluted_coat_color | 0.77529031 |
88 | MP0003828_pulmonary_edema | 0.75448808 |
89 | MP0005165_increased_susceptibility_to | 0.75346665 |
90 | MP0003453_abnormal_keratinocyte_physiol | 0.73846024 |
91 | MP0003646_muscle_fatigue | 0.70051960 |
92 | MP0003763_abnormal_thymus_physiology | 0.68641563 |
93 | MP0003191_abnormal_cellular_cholesterol | 0.67887152 |
94 | MP0005257_abnormal_intraocular_pressure | 0.65226636 |
95 | MP0003329_amyloid_beta_deposits | 0.65181319 |
96 | MP0005023_abnormal_wound_healing | 0.62958244 |
97 | MP0000249_abnormal_blood_vessel | 0.62582112 |
98 | MP0005535_abnormal_body_temperature | 0.62404995 |
99 | MP0003795_abnormal_bone_structure | 0.60856618 |
100 | MP0005647_abnormal_sex_gland | 0.60173334 |
101 | MP0001849_ear_inflammation | 0.59771055 |
102 | MP0002736_abnormal_nociception_after | 0.58904549 |
103 | MP0001440_abnormal_grooming_behavior | 0.57390878 |
104 | MP0003566_abnormal_cell_adhesion | 0.56466087 |
105 | MP0002693_abnormal_pancreas_physiology | 0.56203303 |
106 | MP0002877_abnormal_melanocyte_morpholog | 0.55520066 |
107 | MP0004883_abnormal_blood_vessel | 0.55066838 |
108 | MP0003195_calcinosis | 0.53998865 |
109 | MP0005595_abnormal_vascular_smooth | 0.53623567 |
110 | MP0005319_abnormal_enzyme/_coenzyme | 0.53244082 |
111 | MP0001873_stomach_inflammation | 0.53145254 |
112 | MP0009765_abnormal_xenobiotic_induced | 0.52808667 |
113 | MP0000465_gastrointestinal_hemorrhage | 0.52752978 |
114 | MP0005381_digestive/alimentary_phenotyp | 0.52746429 |
115 | MP0003656_abnormal_erythrocyte_physiolo | 0.52384331 |
116 | MP0001968_abnormal_touch/_nociception | 0.51099867 |
117 | MP0000920_abnormal_myelination | 0.50907959 |
118 | MP0003045_fibrosis | 0.49669739 |
119 | MP0003634_abnormal_glial_cell | 0.49534388 |
120 | MP0003866_abnormal_defecation | 0.49265794 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Recurrent abscess formation (HP:0002722) | 7.45066503 |
2 | Recurrent bacterial skin infections (HP:0005406) | 6.73285625 |
3 | Eczematoid dermatitis (HP:0000976) | 6.62693367 |
4 | Elevated erythrocyte sedimentation rate (HP:0003565) | 6.07622852 |
5 | Stomatitis (HP:0010280) | 5.83231125 |
6 | Recurrent gram-negative bacterial infections (HP:0005420) | 5.77932439 |
7 | Mediastinal lymphadenopathy (HP:0100721) | 5.51156476 |
8 | Abnormality of macrophages (HP:0004311) | 5.34526412 |
9 | Optic neuritis (HP:0100653) | 5.25576260 |
10 | Retrobulbar optic neuritis (HP:0100654) | 5.25576260 |
11 | Orchitis (HP:0100796) | 4.97768187 |
12 | Myositis (HP:0100614) | 4.82776369 |
13 | Gingivitis (HP:0000230) | 4.29232208 |
14 | Recurrent skin infections (HP:0001581) | 4.09176613 |
15 | Vasculitis (HP:0002633) | 4.07367849 |
16 | Autoimmune thrombocytopenia (HP:0001973) | 3.89384610 |
17 | Chronic obstructive pulmonary disease (HP:0006510) | 3.84521032 |
18 | Obstructive lung disease (HP:0006536) | 3.84521032 |
19 | Mutism (HP:0002300) | 3.78944303 |
20 | Vacuolated lymphocytes (HP:0001922) | 3.78090370 |
21 | Systemic lupus erythematosus (HP:0002725) | 3.77035145 |
22 | Recurrent fungal infections (HP:0002841) | 3.75389507 |
23 | Increased cerebral lipofuscin (HP:0011813) | 3.74788380 |
24 | Increased IgM level (HP:0003496) | 3.60052457 |
25 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 3.35888502 |
26 | Pulmonary infiltrates (HP:0002113) | 3.28969746 |
27 | Basal ganglia calcification (HP:0002135) | 3.23644608 |
28 | Recurrent viral infections (HP:0004429) | 3.20291782 |
29 | Nuclear cataract (HP:0100018) | 3.16194847 |
30 | Neurofibrillary tangles (HP:0002185) | 3.15454684 |
31 | Interstitial pulmonary disease (HP:0006530) | 3.12124250 |
32 | Increased serum ferritin (HP:0003281) | 3.05637034 |
33 | Keratoconjunctivitis sicca (HP:0001097) | 3.02804254 |
34 | Periodontitis (HP:0000704) | 3.00461244 |
35 | Prostate neoplasm (HP:0100787) | 2.99188254 |
36 | Thick nail (HP:0001805) | 2.96040561 |
37 | Apathy (HP:0000741) | 2.94015363 |
38 | Recurrent cutaneous fungal infections (HP:0011370) | 2.91591137 |
39 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.91591137 |
40 | Urticaria (HP:0001025) | 2.90168757 |
41 | Diminished motivation (HP:0000745) | 2.89228084 |
42 | Keratoconjunctivitis (HP:0001096) | 2.89080305 |
43 | Chronic otitis media (HP:0000389) | 2.88200320 |
44 | Abnormality of liposaccharide metabolism (HP:0010968) | 2.85298211 |
45 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 2.85298211 |
46 | Abnormality of glycolipid metabolism (HP:0010969) | 2.85298211 |
47 | Arterial thrombosis (HP:0004420) | 2.81920202 |
48 | Tetraparesis (HP:0002273) | 2.80135824 |
49 | Premature loss of primary teeth (HP:0006323) | 2.79036068 |
50 | Gastrointestinal infarctions (HP:0005244) | 2.78098234 |
51 | Cellulitis (HP:0100658) | 2.73973420 |
52 | Meningitis (HP:0001287) | 2.73205246 |
53 | Progressive neurologic deterioration (HP:0002344) | 2.72747318 |
54 | Pustule (HP:0200039) | 2.70630165 |
55 | Leukocytosis (HP:0001974) | 2.69933547 |
56 | Axonal loss (HP:0003447) | 2.69093386 |
57 | Purpura (HP:0000979) | 2.59352506 |
58 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 2.58348398 |
59 | Amyloidosis (HP:0011034) | 2.56025459 |
60 | Neuronal loss in central nervous system (HP:0002529) | 2.55708150 |
61 | Hemoptysis (HP:0002105) | 2.49845221 |
62 | Osteomyelitis (HP:0002754) | 2.48713667 |
63 | Hypergammaglobulinemia (HP:0010702) | 2.48674657 |
64 | Recurrent pneumonia (HP:0006532) | 2.45678234 |
65 | Disinhibition (HP:0000734) | 2.44110035 |
66 | Porencephaly (HP:0002132) | 2.42476665 |
67 | Cerebral inclusion bodies (HP:0100314) | 2.42069847 |
68 | Parakeratosis (HP:0001036) | 2.39421655 |
69 | Abnormality of iron homeostasis (HP:0011031) | 2.31986070 |
70 | Dysostosis multiplex (HP:0000943) | 2.27864689 |
71 | Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204) | 2.26226366 |
72 | Inappropriate behavior (HP:0000719) | 2.23309745 |
73 | Prolonged neonatal jaundice (HP:0006579) | 2.23013601 |
74 | Encephalitis (HP:0002383) | 2.20752572 |
75 | Bone pain (HP:0002653) | 2.20519667 |
76 | Hematochezia (HP:0002573) | 2.16816766 |
77 | Upper motor neuron abnormality (HP:0002127) | 2.14813503 |
78 | Abnormality of the vasculature of the conjunctiva (HP:0008054) | 2.13443051 |
79 | Agnosia (HP:0010524) | 2.12686824 |
80 | Episodic fever (HP:0001954) | 2.11969412 |
81 | Polyneuropathy (HP:0001271) | 2.11835139 |
82 | Gingival bleeding (HP:0000225) | 2.11479806 |
83 | Malnutrition (HP:0004395) | 2.10650013 |
84 | Nasal polyposis (HP:0100582) | 2.09366703 |
85 | Recurrent lower respiratory tract infections (HP:0002783) | 2.09290586 |
86 | Metaphyseal irregularity (HP:0003025) | 2.08704098 |
87 | Increased IgE level (HP:0003212) | 2.08129483 |
88 | Abnormality of the pericardium (HP:0001697) | 2.08051880 |
89 | Hepatosplenomegaly (HP:0001433) | 2.06878460 |
90 | Petechiae (HP:0000967) | 2.06404349 |
91 | Arthralgia (HP:0002829) | 2.04661457 |
92 | Anorexia (HP:0002039) | 2.04190335 |
93 | Colitis (HP:0002583) | 2.02524476 |
94 | Frequent falls (HP:0002359) | 2.02337019 |
95 | Loss of speech (HP:0002371) | 2.01354606 |
96 | Glomerulonephritis (HP:0000099) | 2.01208149 |
97 | Nausea (HP:0002018) | 2.00724618 |
98 | Dementia (HP:0000726) | 1.99990071 |
99 | Memory impairment (HP:0002354) | 1.98561056 |
100 | Nephritis (HP:0000123) | 1.98289374 |
101 | Personality changes (HP:0000751) | 1.96285807 |
102 | Gangrene (HP:0100758) | 1.93913413 |
103 | Abnormality of polysaccharide metabolism (HP:0011012) | 1.93287836 |
104 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 1.93287836 |
105 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 1.93287836 |
106 | Urinary glycosaminoglycan excretion (HP:0003541) | 1.90652036 |
107 | Mucopolysacchariduria (HP:0008155) | 1.90652036 |
108 | Supranuclear gaze palsy (HP:0000605) | 1.89722523 |
109 | Gastrointestinal stroma tumor (HP:0100723) | 1.88681282 |
110 | Abnormality of the pleura (HP:0002103) | 1.87771086 |
111 | Vertebral compression fractures (HP:0002953) | 1.87103488 |
112 | Restrictive lung disease (HP:0002091) | 1.85156816 |
113 | Hypertensive crisis (HP:0100735) | 1.83826499 |
114 | Thin bony cortex (HP:0002753) | 1.83653169 |
115 | IgA deficiency (HP:0002720) | 1.83637232 |
116 | Joint swelling (HP:0001386) | 1.83002496 |
117 | Lymphopenia (HP:0001888) | 1.82873824 |
118 | Abnormality of transition element cation homeostasis (HP:0011030) | 1.82706985 |
119 | Sepsis (HP:0100806) | 1.82700321 |
120 | Vertigo (HP:0002321) | 1.82556443 |
121 | Pathologic fracture (HP:0002756) | 1.81783813 |
122 | Emphysema (HP:0002097) | 1.81669196 |
123 | Peritonitis (HP:0002586) | 1.81003906 |
124 | Myocardial infarction (HP:0001658) | 1.80759157 |
125 | Poor head control (HP:0002421) | 1.80742460 |
126 | Xerostomia (HP:0000217) | 1.80606254 |
127 | Lower limb hyperreflexia (HP:0002395) | 1.80271776 |
128 | Chest pain (HP:0100749) | 1.79995388 |
129 | Eosinophilia (HP:0001880) | 1.79524288 |
130 | Recurrent bronchitis (HP:0002837) | 1.79417953 |
131 | Abnormality of the nasal mucosa (HP:0000433) | 1.76059321 |
132 | Progressive visual loss (HP:0000529) | 1.75065244 |
133 | Abnormality of the endocardium (HP:0004306) | 1.74630175 |
134 | Neoplasm of head and neck (HP:0012288) | 1.73654996 |
Rank | Gene Set | Z-score |
---|---|---|
1 | RIPK4 | 5.34104941 |
2 | MAP3K14 | 4.85618833 |
3 | TBK1 | 4.00734090 |
4 | BLK | 3.97454909 |
5 | NME2 | 3.83728163 |
6 | IRAK3 | 3.47279685 |
7 | IRAK4 | 3.07353891 |
8 | MAP3K13 | 3.07120461 |
9 | TYK2 | 3.03237012 |
10 | IKBKE | 3.03177667 |
11 | TAOK2 | 2.82405236 |
12 | DDR2 | 2.67887106 |
13 | IKBKB | 2.56515395 |
14 | PBK | 2.48887593 |
15 | JAK3 | 2.41659049 |
16 | TAOK1 | 2.33956420 |
17 | TXK | 2.29894857 |
18 | JAK1 | 2.10348582 |
19 | MAP4K1 | 2.08963068 |
20 | KIT | 2.01699930 |
21 | FGR | 1.94751203 |
22 | RIPK1 | 1.89167811 |
23 | MAP3K3 | 1.87962611 |
24 | MAP2K3 | 1.76399305 |
25 | TESK2 | 1.70918807 |
26 | BMPR2 | 1.61703697 |
27 | CDC42BPA | 1.57228158 |
28 | FES | 1.56795420 |
29 | CHUK | 1.54652201 |
30 | SYK | 1.54086912 |
31 | TGFBR2 | 1.45728399 |
32 | DAPK2 | 1.45639790 |
33 | PIM2 | 1.34613120 |
34 | MAP3K9 | 1.27796882 |
35 | HCK | 1.27768016 |
36 | CSK | 1.26435442 |
37 | ARAF | 1.24838569 |
38 | BMX | 1.16497082 |
39 | ERN1 | 1.14384570 |
40 | SIK2 | 1.11614413 |
41 | KSR2 | 1.11566770 |
42 | ZAP70 | 1.07515891 |
43 | LYN | 1.06665443 |
44 | JAK2 | 1.06415613 |
45 | MAP3K12 | 1.06022614 |
46 | LCK | 1.00567744 |
47 | MATK | 0.96165044 |
48 | MARK3 | 0.95772379 |
49 | SIK3 | 0.95551990 |
50 | TYRO3 | 0.95282449 |
51 | TAOK3 | 0.94715260 |
52 | EPHB1 | 0.93036914 |
53 | CSF1R | 0.88518774 |
54 | PLK2 | 0.84207613 |
55 | MAP3K5 | 0.84157133 |
56 | EIF2AK2 | 0.79073082 |
57 | BTK | 0.77910294 |
58 | PIM1 | 0.76056343 |
59 | TESK1 | 0.76034640 |
60 | NEK9 | 0.75342450 |
61 | ABL2 | 0.74714088 |
62 | YES1 | 0.74230351 |
63 | NTRK3 | 0.70778028 |
64 | PRKCD | 0.70388289 |
65 | DAPK3 | 0.69565877 |
66 | GRK7 | 0.67015497 |
67 | EGFR | 0.65980676 |
68 | STK10 | 0.64373456 |
69 | SIK1 | 0.63880810 |
70 | DAPK1 | 0.62941575 |
71 | RPS6KA4 | 0.62407422 |
72 | ACVR1B | 0.58726165 |
73 | ICK | 0.58162440 |
74 | TNK2 | 0.54957331 |
75 | ABL1 | 0.54102693 |
76 | IRAK2 | 0.52684722 |
77 | CAMKK2 | 0.47645920 |
78 | PRKCQ | 0.47389306 |
79 | FYN | 0.47305361 |
80 | DYRK3 | 0.46048551 |
81 | MAP3K1 | 0.45539162 |
82 | MOS | 0.45534555 |
83 | CAMK1D | 0.45010791 |
84 | PDPK1 | 0.44695337 |
85 | TEC | 0.44608618 |
86 | ADRBK2 | 0.44361653 |
87 | PDGFRA | 0.44228188 |
88 | PRKD2 | 0.43694607 |
89 | LATS2 | 0.43505613 |
90 | PTK2B | 0.43488656 |
91 | MAPK4 | 0.42555070 |
92 | MAP3K11 | 0.41348181 |
93 | IRAK1 | 0.41275102 |
94 | PKN1 | 0.41127915 |
95 | MST1R | 0.40705911 |
96 | RPS6KC1 | 0.40317082 |
97 | RPS6KL1 | 0.40317082 |
98 | PTK6 | 0.39881129 |
99 | FGFR3 | 0.39809751 |
100 | PDK1 | 0.38322603 |
101 | MAP2K6 | 0.38229966 |
102 | SGK1 | 0.37893116 |
103 | HIPK2 | 0.37333488 |
104 | RAF1 | 0.36495273 |
105 | MARK2 | 0.36389023 |
106 | BRAF | 0.34386269 |
107 | TTN | 0.34385034 |
108 | TRIB3 | 0.34164414 |
109 | CLK1 | 0.33503535 |
110 | PAK4 | 0.32717341 |
111 | ERBB4 | 0.32590749 |
112 | MST4 | 0.32205374 |
113 | FGFR4 | 0.30926411 |
114 | EPHA3 | 0.30359669 |
115 | MAP3K10 | 0.30194984 |
116 | PRPF4B | 0.29749134 |
117 | ERBB3 | 0.29305852 |
118 | GRK5 | 0.28661737 |
119 | GRK6 | 0.27913000 |
120 | PRKCE | 0.27001472 |
121 | RPS6KA2 | 0.26644057 |
122 | MAP3K8 | 0.25493286 |
123 | LIMK1 | 0.25395361 |
124 | SRC | 0.24852123 |
125 | STK4 | 0.24758796 |
126 | TRPM7 | 0.24544342 |
127 | CDK14 | 0.24379127 |
128 | PAK6 | 0.24215384 |
129 | MAPKAPK2 | 0.23088427 |
130 | DYRK1B | 0.22844038 |
131 | NTRK1 | 0.21487690 |
132 | SMG1 | 0.20757863 |
133 | MAPK7 | 0.19354166 |
134 | CDK6 | 0.18408582 |
135 | PRKCZ | 0.17946753 |
136 | KSR1 | 0.17475521 |
137 | ALK | 0.17161996 |
138 | PRKCH | 0.16472457 |
139 | INSR | 0.16444613 |
140 | RPS6KA6 | 0.16061295 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.26541512 |
2 | Leishmaniasis_Homo sapiens_hsa05140 | 3.19684715 |
3 | Allograft rejection_Homo sapiens_hsa05330 | 2.82894242 |
4 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.80443252 |
5 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 2.67008737 |
6 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.50087372 |
7 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 2.49946133 |
8 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.47028936 |
9 | Pertussis_Homo sapiens_hsa05133 | 2.43940030 |
10 | Legionellosis_Homo sapiens_hsa05134 | 2.42385870 |
11 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.39580445 |
12 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.36514717 |
13 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.32559019 |
14 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 2.26553261 |
15 | Tuberculosis_Homo sapiens_hsa05152 | 2.24505175 |
16 | TNF signaling pathway_Homo sapiens_hsa04668 | 2.12030764 |
17 | Asthma_Homo sapiens_hsa05310 | 2.04830703 |
18 | Malaria_Homo sapiens_hsa05144 | 2.00073141 |
19 | Measles_Homo sapiens_hsa05162 | 1.96153927 |
20 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.90656921 |
21 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.89756788 |
22 | Influenza A_Homo sapiens_hsa05164 | 1.86422551 |
23 | Salmonella infection_Homo sapiens_hsa05132 | 1.73185824 |
24 | Phagosome_Homo sapiens_hsa04145 | 1.63576084 |
25 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.56109151 |
26 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.54167206 |
27 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.49489467 |
28 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.47049922 |
29 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.41035970 |
30 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.40159699 |
31 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.40081474 |
32 | Lysosome_Homo sapiens_hsa04142 | 1.37817719 |
33 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.33368559 |
34 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.28037028 |
35 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.26654211 |
36 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.24131070 |
37 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.23738884 |
38 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.22662156 |
39 | Apoptosis_Homo sapiens_hsa04210 | 1.21892206 |
40 | Shigellosis_Homo sapiens_hsa05131 | 1.18571183 |
41 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.11381540 |
42 | Bladder cancer_Homo sapiens_hsa05219 | 1.07458094 |
43 | Hepatitis C_Homo sapiens_hsa05160 | 1.04178120 |
44 | Hepatitis B_Homo sapiens_hsa05161 | 0.99114838 |
45 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.98198690 |
46 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.97392572 |
47 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.96254116 |
48 | Amoebiasis_Homo sapiens_hsa05146 | 0.95313677 |
49 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.92852634 |
50 | Viral myocarditis_Homo sapiens_hsa05416 | 0.90229063 |
51 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.89833601 |
52 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.85449353 |
53 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.79808462 |
54 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.77318253 |
55 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.74718019 |
56 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.74138194 |
57 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.73897982 |
58 | Other glycan degradation_Homo sapiens_hsa00511 | 0.73486583 |
59 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.71327308 |
60 | Prion diseases_Homo sapiens_hsa05020 | 0.71220016 |
61 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.68426497 |
62 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.67389318 |
63 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.65615923 |
64 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.64513816 |
65 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.59445614 |
66 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.59176594 |
67 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.58532886 |
68 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.57495106 |
69 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.53980355 |
70 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.53149678 |
71 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.51138102 |
72 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.50622860 |
73 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.49136648 |
74 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.47905833 |
75 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.47018509 |
76 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.45611950 |
77 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.45600777 |
78 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.45260236 |
79 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.41630495 |
80 | HTLV-I infection_Homo sapiens_hsa05166 | 0.41219775 |
81 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.40834173 |
82 | Platelet activation_Homo sapiens_hsa04611 | 0.38734157 |
83 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.38432414 |
84 | Galactose metabolism_Homo sapiens_hsa00052 | 0.38180156 |
85 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.37687820 |
86 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.35880064 |
87 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.35543854 |
88 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.34871600 |
89 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.34178793 |
90 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.33020243 |
91 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.32633456 |
92 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.32325469 |
93 | Mineral absorption_Homo sapiens_hsa04978 | 0.31859557 |
94 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.30712929 |
95 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.28997702 |
96 | Glioma_Homo sapiens_hsa05214 | 0.27834761 |
97 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.27203378 |
98 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.23242715 |
99 | Endocytosis_Homo sapiens_hsa04144 | 0.22839617 |
100 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.20505076 |
101 | Insulin resistance_Homo sapiens_hsa04931 | 0.20449380 |
102 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.19109290 |
103 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.18801253 |
104 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.18655121 |
105 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.18645384 |
106 | Morphine addiction_Homo sapiens_hsa05032 | 0.16772254 |
107 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.16436629 |
108 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.16213669 |
109 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.15702401 |
110 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.15647519 |
111 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.13936742 |
112 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.13836718 |
113 | Nicotine addiction_Homo sapiens_hsa05033 | 0.12749602 |
114 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.12122319 |
115 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.10230983 |
116 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.05532973 |