SLC32A1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is an integral membrane protein involved in gamma-aminobutyric acid (GABA) and glycine uptake into synaptic vesicles. The encoded protein is a member of amino acid/polyamine transporter family II. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1pyrimidine nucleobase catabolic process (GO:0006208)6.54805486
2synaptic vesicle maturation (GO:0016188)6.46111483
3regulation of short-term neuronal synaptic plasticity (GO:0048172)6.34576924
4locomotory exploration behavior (GO:0035641)6.17797123
5positive regulation of excitatory postsynaptic membrane potential (GO:2000463)6.02571582
6vocalization behavior (GO:0071625)5.84803289
7positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.61968277
8regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.41147930
9nucleobase catabolic process (GO:0046113)5.40319488
10establishment of mitochondrion localization (GO:0051654)5.35774862
11synaptic vesicle exocytosis (GO:0016079)5.26069869
12regulation of glutamate receptor signaling pathway (GO:1900449)5.07361059
13regulation of synapse structural plasticity (GO:0051823)5.01697105
14regulation of synaptic vesicle exocytosis (GO:2000300)4.97964498
15regulation of long-term neuronal synaptic plasticity (GO:0048169)4.91737394
16* neurotransmitter secretion (GO:0007269)4.77700153
17layer formation in cerebral cortex (GO:0021819)4.77395828
18regulation of neuronal synaptic plasticity (GO:0048168)4.72320693
19axonal fasciculation (GO:0007413)4.72150246
20glutamate secretion (GO:0014047)4.71319807
21ionotropic glutamate receptor signaling pathway (GO:0035235)4.71258244
22cell migration in hindbrain (GO:0021535)4.64991746
23glycosphingolipid biosynthetic process (GO:0006688)4.63141059
24synaptic vesicle docking involved in exocytosis (GO:0016081)4.60584484
25protein localization to synapse (GO:0035418)4.60496950
26exploration behavior (GO:0035640)4.54903394
27neuronal action potential propagation (GO:0019227)4.50704942
28dendritic spine morphogenesis (GO:0060997)4.47632030
29regulation of synaptic vesicle transport (GO:1902803)4.42799137
30neurotransmitter-gated ion channel clustering (GO:0072578)4.37999085
31prepulse inhibition (GO:0060134)4.35154290
32neuron cell-cell adhesion (GO:0007158)4.23251473
33auditory behavior (GO:0031223)4.18894158
34positive regulation of synaptic transmission, dopaminergic (GO:0032226)4.18308243
35membrane depolarization during cardiac muscle cell action potential (GO:0086012)4.14796747
36neuromuscular process controlling balance (GO:0050885)4.13051660
37synaptic transmission, glutamatergic (GO:0035249)4.12886656
38positive regulation of synaptic transmission, GABAergic (GO:0032230)4.10367007
39long-term memory (GO:0007616)4.09697045
40cellular potassium ion homeostasis (GO:0030007)4.02694551
41neuron-neuron synaptic transmission (GO:0007270)4.02129868
42positive regulation of membrane potential (GO:0045838)4.00081464
43glutamate receptor signaling pathway (GO:0007215)3.99637019
44sodium ion export (GO:0071436)3.95643942
45regulation of dendritic spine morphogenesis (GO:0061001)3.89523833
46regulation of excitatory postsynaptic membrane potential (GO:0060079)3.88003227
47regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.85693290
48presynaptic membrane assembly (GO:0097105)3.85594612
49amino acid import (GO:0043090)3.85239414
50* gamma-aminobutyric acid transport (GO:0015812)3.84176405
51response to auditory stimulus (GO:0010996)3.82804025
52proline transport (GO:0015824)3.81410592
53positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.80228585
54* neurotransmitter transport (GO:0006836)3.77042785
55neuromuscular process controlling posture (GO:0050884)3.75974210
56neurofilament cytoskeleton organization (GO:0060052)3.75926135
57transmission of nerve impulse (GO:0019226)3.74877903
58presynaptic membrane organization (GO:0097090)3.72379639
59protein-cofactor linkage (GO:0018065)3.70487046
60activation of protein kinase A activity (GO:0034199)3.69382100
61regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.68643971
62negative regulation of oligodendrocyte differentiation (GO:0048715)3.67523073
63positive regulation of synapse maturation (GO:0090129)3.64913519
64regulation of postsynaptic membrane potential (GO:0060078)3.62378936
65neuronal ion channel clustering (GO:0045161)3.62086650
66hippocampus development (GO:0021766)3.58469082
67regulation of synaptic plasticity (GO:0048167)3.55900806
68* regulation of neurotransmitter levels (GO:0001505)3.54261761
69positive regulation of neurotransmitter transport (GO:0051590)3.51073387
70regulation of synaptic transmission, glutamatergic (GO:0051966)3.49977912
71regulation of synapse maturation (GO:0090128)3.49753738
72establishment of mitochondrion localization, microtubule-mediated (GO:0034643)3.47060611
73mitochondrion transport along microtubule (GO:0047497)3.47060611
74behavioral response to nicotine (GO:0035095)3.44555436
75positive regulation of mitochondrial fission (GO:0090141)3.43062051
76neuromuscular synaptic transmission (GO:0007274)3.40711573
77dopamine receptor signaling pathway (GO:0007212)3.40301921
78cerebellar Purkinje cell differentiation (GO:0021702)3.37237349
79negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.36192496
80membrane hyperpolarization (GO:0060081)3.35565909
81adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)3.33446265
82regulation of female receptivity (GO:0045924)3.32838622
83regulation of neurotransmitter secretion (GO:0046928)3.32663992
84striatum development (GO:0021756)3.32144465
85synaptic transmission, dopaminergic (GO:0001963)3.28959025
86dicarboxylic acid catabolic process (GO:0043649)3.27635958
87neuromuscular process (GO:0050905)3.27393874
88neuron recognition (GO:0008038)3.27004698
89ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043163.24646986
90G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.24267912
91regulation of vesicle fusion (GO:0031338)3.23167626
92synaptic vesicle endocytosis (GO:0048488)3.23105557
93behavioral response to cocaine (GO:0048148)3.21989258
94regulation of neurotransmitter transport (GO:0051588)3.21932501
95positive regulation of dendritic spine development (GO:0060999)3.21208816
96positive regulation of neurotransmitter secretion (GO:0001956)3.21153308
97positive regulation of synapse assembly (GO:0051965)3.20739110
98learning (GO:0007612)3.20613659
99mating behavior (GO:0007617)3.19701469
100cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.19593923
101regulation of synaptic transmission, GABAergic (GO:0032228)3.17357396
102long-term synaptic potentiation (GO:0060291)3.16501352
103dendrite morphogenesis (GO:0048813)3.16064120
104L-amino acid import (GO:0043092)3.15785444
105membrane depolarization (GO:0051899)3.15615190
106postsynaptic membrane organization (GO:0001941)3.15245007
107mechanosensory behavior (GO:0007638)3.13990008
108regulation of dendritic spine development (GO:0060998)3.13774335
109substrate-independent telencephalic tangential migration (GO:0021826)3.13563094
110substrate-independent telencephalic tangential interneuron migration (GO:0021843)3.13563094
111negative regulation of synaptic transmission, GABAergic (GO:0032229)3.12373921
112cerebellar granule cell differentiation (GO:0021707)3.10792576
113positive regulation of dendritic spine morphogenesis (GO:0061003)3.10138072
114cell communication by electrical coupling (GO:0010644)3.10089531
115succinate metabolic process (GO:0006105)3.08595015
116establishment of synaptic vesicle localization (GO:0097480)3.08244411
117synaptic vesicle transport (GO:0048489)3.08244411
118membrane depolarization during action potential (GO:0086010)3.07878821
119positive regulation of synaptic transmission (GO:0050806)3.07070177
120gamma-aminobutyric acid signaling pathway (GO:0007214)3.06038477
121synapse organization (GO:0050808)3.05892884
122visual learning (GO:0008542)3.05675528
123adenosine receptor signaling pathway (GO:0001973)3.05215406
124intraspecies interaction between organisms (GO:0051703)3.05130064
125social behavior (GO:0035176)3.05130064
126positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.05097061
127calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)3.04177776
128adult walking behavior (GO:0007628)3.03475455
129synapse assembly (GO:0007416)3.02166529
130heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0007157)3.01705970
131response to dietary excess (GO:0002021)2.98736186
132establishment of vesicle localization (GO:0051650)2.98559379
133regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.97897298
134neurotransmitter biosynthetic process (GO:0042136)2.96839129
135G-protein coupled glutamate receptor signaling pathway (GO:0007216)2.96629956
136* synaptic transmission (GO:0007268)2.95392740
137protein insertion into membrane (GO:0051205)2.92433525
138startle response (GO:0001964)2.91742929
139regulation of protein kinase A signaling (GO:0010738)2.90761750

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.77026074
2RARB_27405468_Chip-Seq_BRAIN_Mouse3.29711590
3IGF1R_20145208_ChIP-Seq_DFB_Human3.19407276
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.19018168
5* SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.12504644
6* JARID2_20064375_ChIP-Seq_MESCs_Mouse3.06675635
7* REST_21632747_ChIP-Seq_MESCs_Mouse2.91914940
8EZH2_18974828_ChIP-Seq_MESCs_Mouse2.84402729
9RNF2_18974828_ChIP-Seq_MESCs_Mouse2.84402729
10DROSHA_22980978_ChIP-Seq_HELA_Human2.82626271
11GBX2_23144817_ChIP-Seq_PC3_Human2.79657005
12* JARID2_20075857_ChIP-Seq_MESCs_Mouse2.73902121
13MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.64723732
14* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.63544239
15* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.62817166
16* EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.57050464
17* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.54963936
18* SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.51827698
19* EZH2_27304074_Chip-Seq_ESCs_Mouse2.51705179
20IKZF1_21737484_ChIP-ChIP_HCT116_Human2.49323531
21* REST_18959480_ChIP-ChIP_MESCs_Mouse2.46318031
22* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.46028160
23* EZH2_27294783_Chip-Seq_ESCs_Mouse2.42359676
24* SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.39832537
25CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.36136208
26TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.29858244
27NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.25201190
28* RNF2_27304074_Chip-Seq_ESCs_Mouse2.24867441
29* EED_16625203_ChIP-ChIP_MESCs_Mouse2.08689532
30ERG_21242973_ChIP-ChIP_JURKAT_Human2.08512383
31ZFP57_27257070_Chip-Seq_ESCs_Mouse2.03487147
32AR_21572438_ChIP-Seq_LNCaP_Human1.88345762
33ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.87327570
34VDR_22108803_ChIP-Seq_LS180_Human1.75483880
35DNAJC2_21179169_ChIP-ChIP_NT2_Human1.63259373
36GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.57744174
37* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.56948019
38POU3F2_20337985_ChIP-ChIP_501MEL_Human1.55773283
39TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.53777098
40ZFP281_18757296_ChIP-ChIP_E14_Mouse1.51297962
41* KDM2B_26808549_Chip-Seq_K562_Human1.47729298
42* RING1B_27294783_Chip-Seq_ESCs_Mouse1.43839564
43NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.41677495
44FUS_26573619_Chip-Seq_HEK293_Human1.38807987
45CTBP2_25329375_ChIP-Seq_LNCAP_Human1.38531958
46SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.34542599
47* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.34160660
48ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.32525973
49* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.29923655
50SMAD4_21799915_ChIP-Seq_A2780_Human1.27866945
51TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.27412200
52RBPJ_22232070_ChIP-Seq_NCS_Mouse1.25250344
53* WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.25053858
54FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.24753104
55WT1_25993318_ChIP-Seq_PODOCYTE_Human1.24193454
56* RING1B_27294783_Chip-Seq_NPCs_Mouse1.23367728
57HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.21590017
58CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.20826353
59* AR_19668381_ChIP-Seq_PC3_Human1.20093350
60* SOX2_21211035_ChIP-Seq_LN229_Gbm1.18533257
61SRY_22984422_ChIP-ChIP_TESTIS_Rat1.18400368
62CTBP1_25329375_ChIP-Seq_LNCAP_Human1.18358454
63GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.18164437
64ZFP281_27345836_Chip-Seq_ESCs_Mouse1.17084036
65GATA1_26923725_Chip-Seq_HPCs_Mouse1.15126017
66CBP_20019798_ChIP-Seq_JUKART_Human1.14986132
67IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.14986132
68SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.14560613
69RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.14217473
70P53_22127205_ChIP-Seq_FIBROBLAST_Human1.13258242
71* PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.12398349
72POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.11021284
73TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.11021284
74ZNF274_21170338_ChIP-Seq_K562_Hela1.10463806
75TAF15_26573619_Chip-Seq_HEK293_Human1.10153900
76IRF1_19129219_ChIP-ChIP_H3396_Human1.08897403
77PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.07306100
78TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05540673
79PIAS1_25552417_ChIP-Seq_VCAP_Human1.04396870
80NR3C1_23031785_ChIP-Seq_PC12_Mouse1.03489847
81SMAD3_21741376_ChIP-Seq_EPCs_Human1.03294208
82CTCF_27219007_Chip-Seq_Bcells_Human1.02844940
83TET1_21490601_ChIP-Seq_MESCs_Mouse1.02149460
84STAT3_23295773_ChIP-Seq_U87_Human1.01364862
85SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.01200933
86* SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.00096318
87TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.99836213
88MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.99280647
89* RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.97781129
90CBX2_27304074_Chip-Seq_ESCs_Mouse0.97154314
91VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.96684793
92MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.96228204
93TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.95788528
94AR_25329375_ChIP-Seq_VCAP_Human0.95453781
95KLF5_20875108_ChIP-Seq_MESCs_Mouse0.95396519
96KDM2B_26808549_Chip-Seq_SUP-B15_Human0.95316110
97YAP1_20516196_ChIP-Seq_MESCs_Mouse0.94620508
98UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.94609287
99SMAD3_21741376_ChIP-Seq_HESCs_Human0.94290860
100PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.90274860
101SMAD4_21741376_ChIP-Seq_HESCs_Human0.90201546
102* SMAD3_21741376_ChIP-Seq_ESCs_Human0.89488168
103DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.88320258
104TCF4_23295773_ChIP-Seq_U87_Human0.87889166
105KLF4_19829295_ChIP-Seq_ESCs_Human0.87824165
106ZNF217_24962896_ChIP-Seq_MCF-7_Human0.87791189
107RNF2_27304074_Chip-Seq_NSC_Mouse0.87300251
108SMAD_19615063_ChIP-ChIP_OVARY_Human0.86981845
109TP53_22573176_ChIP-Seq_HFKS_Human0.86569680
110AHR_22903824_ChIP-Seq_MCF-7_Human0.86421679
111THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.86345525
112TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.86337481
113P300_19829295_ChIP-Seq_ESCs_Human0.86037822
114ZFP281_18358816_ChIP-ChIP_MESCs_Mouse0.85942482
115GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.85222108
116MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.84321304
117ARNT_22903824_ChIP-Seq_MCF-7_Human0.83684522
118TOP2B_26459242_ChIP-Seq_MCF-7_Human0.82944501
119THAP11_20581084_ChIP-Seq_MESCs_Mouse0.82726727
120OCT4_19829295_ChIP-Seq_ESCs_Human0.81545640
121SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.81532473
122LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.81199631
123SMC4_20622854_ChIP-Seq_HELA_Human0.81118524
124OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.81023577
125* BMI1_23680149_ChIP-Seq_NPCS_Mouse0.80756546
126* KDM2B_26808549_Chip-Seq_JURKAT_Human0.80107030
127RUNX2_22187159_ChIP-Seq_PCA_Human0.80034192
128TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.79760763
129OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.79347514
130LXR_22292898_ChIP-Seq_THP-1_Human0.79345667
131PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.77961379
132TP53_20018659_ChIP-ChIP_R1E_Mouse0.77772572
133JUN_21703547_ChIP-Seq_K562_Human0.77635026
134CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.76597571
135ETV2_25802403_ChIP-Seq_MESCs_Mouse0.76019773
136SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.75674493
137TAL1_26923725_Chip-Seq_HPCs_Mouse0.75204624

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.66260775
2MP0002822_catalepsy4.78616422
3MP0003880_abnormal_central_pattern4.33347769
4* MP0003635_abnormal_synaptic_transmissio4.32970611
5MP0009745_abnormal_behavioral_response3.69375177
6MP0009046_muscle_twitch3.57675075
7MP0002063_abnormal_learning/memory/cond3.47308138
8MP0004270_analgesia3.42662489
9MP0002064_seizures3.39482580
10MP0005423_abnormal_somatic_nervous3.17394501
11MP0002572_abnormal_emotion/affect_behav2.88028839
12MP0001486_abnormal_startle_reflex2.74701478
13* MP0002272_abnormal_nervous_system2.63518423
14MP0001968_abnormal_touch/_nociception2.61338653
15MP0002734_abnormal_mechanical_nocicepti2.47881258
16MP0001986_abnormal_taste_sensitivity2.33975172
17MP0008569_lethality_at_weaning2.23143228
18MP0001501_abnormal_sleep_pattern2.23119191
19MP0002909_abnormal_adrenal_gland2.07613823
20MP0002733_abnormal_thermal_nociception2.06511126
21MP0001970_abnormal_pain_threshold2.00476237
22MP0001440_abnormal_grooming_behavior1.94307101
23MP0004811_abnormal_neuron_physiology1.91037953
24MP0008789_abnormal_olfactory_epithelium1.90770593
25MP0004924_abnormal_behavior1.86935001
26MP0005386_behavior/neurological_phenoty1.86935001
27MP0002067_abnormal_sensory_capabilities1.84705468
28MP0002557_abnormal_social/conspecific_i1.83037798
29MP0002736_abnormal_nociception_after1.82163202
30MP0003329_amyloid_beta_deposits1.78895572
31MP0009780_abnormal_chondrocyte_physiolo1.77509703
32MP0005646_abnormal_pituitary_gland1.77111059
33MP0002102_abnormal_ear_morphology1.75642516
34MP0001529_abnormal_vocalization1.75447479
35MP0004885_abnormal_endolymph1.75112307
36MP0002184_abnormal_innervation1.74908699
37MP0000955_abnormal_spinal_cord1.62997624
38MP0002735_abnormal_chemical_nociception1.61059005
39MP0008995_early_reproductive_senescence1.59018072
40MP0000778_abnormal_nervous_system1.57274472
41MP0004858_abnormal_nervous_system1.52499351
42* MP0002066_abnormal_motor_capabilities/c1.49104283
43MP0003879_abnormal_hair_cell1.46289465
44MP0001984_abnormal_olfaction1.46230617
45MP0003121_genomic_imprinting1.45534178
46MP0002882_abnormal_neuron_morphology1.40204753
47MP0001502_abnormal_circadian_rhythm1.39153988
48MP0001270_distended_abdomen1.38910490
49MP0003633_abnormal_nervous_system1.36929761
50* MP0004142_abnormal_muscle_tone1.29104729
51MP0003283_abnormal_digestive_organ1.24561743
52MP0005645_abnormal_hypothalamus_physiol1.23655965
53MP0008872_abnormal_physiological_respon1.15672195
54MP0003690_abnormal_glial_cell1.14807152
55MP0006276_abnormal_autonomic_nervous1.14585632
56MP0003787_abnormal_imprinting1.14391974
57MP0000049_abnormal_middle_ear1.13514712
58MP0003631_nervous_system_phenotype1.13364888
59MP0002152_abnormal_brain_morphology1.12666205
60MP0008961_abnormal_basal_metabolism1.12288555
61MP0003938_abnormal_ear_development1.11365030
62MP0003075_altered_response_to1.10435449
63MP0008874_decreased_physiological_sensi1.08583004
64MP0001905_abnormal_dopamine_level1.08303396
65MP0001177_atelectasis1.07540660
66MP0008877_abnormal_DNA_methylation1.06643876
67MP0000569_abnormal_digit_pigmentation1.02752288
68MP0002069_abnormal_eating/drinking_beha0.99052046
69MP0002229_neurodegeneration0.98602749
70MP0000751_myopathy0.96001348
71MP0000920_abnormal_myelination0.95657288
72MP0005167_abnormal_blood-brain_barrier0.94849146
73MP0003634_abnormal_glial_cell0.94752212
74MP0003122_maternal_imprinting0.94311125
75MP0004043_abnormal_pH_regulation0.90067887
76MP0005394_taste/olfaction_phenotype0.88771799
77MP0005499_abnormal_olfactory_system0.88771799
78MP0001188_hyperpigmentation0.87398811
79MP0002751_abnormal_autonomic_nervous0.86918438
80MP0004085_abnormal_heartbeat0.86390345
81MP0005551_abnormal_eye_electrophysiolog0.85795848
82MP0004145_abnormal_muscle_electrophysio0.85750458
83MP0002876_abnormal_thyroid_physiology0.83900960
84MP0003632_abnormal_nervous_system0.83035740
85MP0005535_abnormal_body_temperature0.82051607
86MP0006035_abnormal_mitochondrial_morpho0.81263694
87MP0003137_abnormal_impulse_conducting0.80604373
88MP0004742_abnormal_vestibular_system0.79871720
89MP0005409_darkened_coat_color0.78886253
90MP0004233_abnormal_muscle_weight0.78791824
91MP0000604_amyloidosis0.78652751
92MP0002653_abnormal_ependyma_morphology0.78080658
93MP0002090_abnormal_vision0.77249507
94MP0004133_heterotaxia0.74795877
95MP0000026_abnormal_inner_ear0.68779187
96MP0005253_abnormal_eye_physiology0.68276652
97MP0002752_abnormal_somatic_nervous0.67038463
98MP0003172_abnormal_lysosome_physiology0.66544413
99MP0005187_abnormal_penis_morphology0.66475063
100MP0000631_abnormal_neuroendocrine_gland0.65729891
101MP0005084_abnormal_gallbladder_morpholo0.63970086
102MP0001963_abnormal_hearing_physiology0.63581265
103MP0010234_abnormal_vibrissa_follicle0.63477189
104* MP0003385_abnormal_body_wall0.63083167
105MP0001485_abnormal_pinna_reflex0.62336387
106MP0002638_abnormal_pupillary_reflex0.61265337
107MP0010769_abnormal_survival0.59281787
108MP0003011_delayed_dark_adaptation0.57930900
109MP0005623_abnormal_meninges_morphology0.57282222
110MP0002082_postnatal_lethality0.57151157
111MP0010770_preweaning_lethality0.57151157
112MP0004147_increased_porphyrin_level0.56760684
113MP0010768_mortality/aging0.55700215
114* MP0002081_perinatal_lethality0.54626386
115MP0010386_abnormal_urinary_bladder0.54448286
116MP0002234_abnormal_pharynx_morphology0.53772685
117* MP0001943_abnormal_respiration0.53564194
118MP0003861_abnormal_nervous_system0.53449598
119MP0003956_abnormal_body_size0.52808858
120MP0006072_abnormal_retinal_apoptosis0.51354033
121MP0004215_abnormal_myocardial_fiber0.47490198
122MP0001664_abnormal_digestion0.46683356
123MP0001299_abnormal_eye_distance/0.45280238

Predicted human phenotypes

RankGene SetZ-score
1Myokymia (HP:0002411)7.73403639
2Focal motor seizures (HP:0011153)7.24844878
3Focal seizures (HP:0007359)5.59863173
4Visual hallucinations (HP:0002367)5.36048905
5Action tremor (HP:0002345)4.22872427
6Atonic seizures (HP:0010819)4.15125742
7Epileptic encephalopathy (HP:0200134)4.13434267
8Gait imbalance (HP:0002141)4.04165722
9Progressive cerebellar ataxia (HP:0002073)4.03278629
10Febrile seizures (HP:0002373)3.99528188
11Absence seizures (HP:0002121)3.89307191
12Ankle clonus (HP:0011448)3.88556655
13Supranuclear gaze palsy (HP:0000605)3.79295814
14Nephrogenic diabetes insipidus (HP:0009806)3.71064903
15Generalized tonic-clonic seizures (HP:0002069)3.65209398
16Dysdiadochokinesis (HP:0002075)3.61924469
17Poor eye contact (HP:0000817)3.61748127
18Mutism (HP:0002300)3.56637779
19Depression (HP:0000716)3.52786006
20Dialeptic seizures (HP:0011146)3.50077950
21Annular pancreas (HP:0001734)3.42553772
22Torticollis (HP:0000473)3.42185221
23Congenital primary aphakia (HP:0007707)3.41925491
24Broad-based gait (HP:0002136)3.41093163
25Abnormal social behavior (HP:0012433)3.38209290
26Impaired social interactions (HP:0000735)3.38209290
27Anxiety (HP:0000739)3.38167785
28Impaired vibration sensation in the lower limbs (HP:0002166)3.32472252
29Focal dystonia (HP:0004373)3.27538764
30Papilledema (HP:0001085)3.24995875
31Postural instability (HP:0002172)3.24970869
32Absent speech (HP:0001344)3.23209780
33Gaze-evoked nystagmus (HP:0000640)3.20620007
34Urinary bladder sphincter dysfunction (HP:0002839)3.18427080
35Dysmetria (HP:0001310)3.16835158
36Split foot (HP:0001839)3.16502312
37Cortical dysplasia (HP:0002539)3.15914341
38Lissencephaly (HP:0001339)3.14672169
39Medial flaring of the eyebrow (HP:0010747)3.09353524
40Cerebral hypomyelination (HP:0006808)3.08160787
41Spastic tetraplegia (HP:0002510)3.07982758
42Limb dystonia (HP:0002451)3.05495945
43Abnormal eating behavior (HP:0100738)3.04109174
44Intention tremor (HP:0002080)2.97390122
45Truncal ataxia (HP:0002078)2.94465811
46Abnormality of the labia minora (HP:0012880)2.90381853
47Hemiplegia (HP:0002301)2.89722068
48Abnormality of the lower motor neuron (HP:0002366)2.88509510
49Thyroid-stimulating hormone excess (HP:0002925)2.86789044
50Craniofacial dystonia (HP:0012179)2.85711927
51Urinary urgency (HP:0000012)2.80279478
52Progressive inability to walk (HP:0002505)2.76379297
53Vaginal atresia (HP:0000148)2.76001963
54Resting tremor (HP:0002322)2.72255916
55Ventricular fibrillation (HP:0001663)2.72142539
56Spastic gait (HP:0002064)2.70841265
57Aplasia/Hypoplasia of the brainstem (HP:0007362)2.69949613
58Hypoplasia of the brainstem (HP:0002365)2.69949613
59Genetic anticipation (HP:0003743)2.69242504
60Retinal dysplasia (HP:0007973)2.68383399
61Stereotypic behavior (HP:0000733)2.67681035
62Genital tract atresia (HP:0001827)2.67521712
63Scanning speech (HP:0002168)2.67199633
64CNS hypomyelination (HP:0003429)2.64366660
65Poor suck (HP:0002033)2.63252042
66Impaired smooth pursuit (HP:0007772)2.63185037
67Hemiparesis (HP:0001269)2.61847925
68Pointed chin (HP:0000307)2.57354117
69Bradykinesia (HP:0002067)2.54178577
70Neurofibrillary tangles (HP:0002185)2.53345420
71Esotropia (HP:0000565)2.51824676
72Tetraplegia (HP:0002445)2.51168096
73Dysmetric saccades (HP:0000641)2.50684331
74Sleep apnea (HP:0010535)2.49089684
75Megalencephaly (HP:0001355)2.43444467
76Pachygyria (HP:0001302)2.42395178
77Poor coordination (HP:0002370)2.42221865
78Status epilepticus (HP:0002133)2.42138224
79Diplopia (HP:0000651)2.40741595
80Abnormality of binocular vision (HP:0011514)2.40741595
81Hypoplasia of the corpus callosum (HP:0002079)2.40199177
82Failure to thrive in infancy (HP:0001531)2.36042143
83Cerebral inclusion bodies (HP:0100314)2.33590914
84Dyskinesia (HP:0100660)2.33396961
85Abnormality of ocular smooth pursuit (HP:0000617)2.32507477
86Fetal akinesia sequence (HP:0001989)2.31475052
87Ankyloglossia (HP:0010296)2.31038354
88Paraplegia (HP:0010550)2.30864956
89Insomnia (HP:0100785)2.30226372
90Clonus (HP:0002169)2.29875966
91Amblyopia (HP:0000646)2.28761130
92Lower limb amyotrophy (HP:0007210)2.28145972
93Peripheral hypomyelination (HP:0007182)2.27667751
94Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.27073778
95Degeneration of the lateral corticospinal tracts (HP:0002314)2.27073778
96Generalized myoclonic seizures (HP:0002123)2.24218475
97Drooling (HP:0002307)2.22823626
98Excessive salivation (HP:0003781)2.22823626
99EEG with generalized epileptiform discharges (HP:0011198)2.22088449
100Hypsarrhythmia (HP:0002521)2.20505574
101Hyperventilation (HP:0002883)2.20222462
102Lower limb muscle weakness (HP:0007340)2.20197920
103Epileptiform EEG discharges (HP:0011182)2.19518489
104Amyotrophic lateral sclerosis (HP:0007354)2.16433651
105Synostosis involving the elbow (HP:0003938)2.15959263
106Humeroradial synostosis (HP:0003041)2.15959263
107Spastic paraplegia (HP:0001258)2.15490951
108Neuronal loss in central nervous system (HP:0002529)2.14404450
109Impaired vibratory sensation (HP:0002495)2.14276943
110Inability to walk (HP:0002540)2.14177722
111Abnormality of the corticospinal tract (HP:0002492)2.11154379
112Obstructive sleep apnea (HP:0002870)2.11076080
113Abnormal EKG (HP:0003115)2.08313895
114Progressive microcephaly (HP:0000253)2.06795833
115Pendular nystagmus (HP:0012043)2.03073887
116Delusions (HP:0000746)2.02100715
117Abnormality of saccadic eye movements (HP:0000570)1.99414656
118Morphological abnormality of the pyramidal tract (HP:0002062)1.99067090
119Termporal pattern (HP:0011008)1.98684747
120Insidious onset (HP:0003587)1.98684747
121Bundle branch block (HP:0011710)1.96860039
122Incomplete penetrance (HP:0003829)1.95604026
123Intellectual disability, severe (HP:0010864)1.95512367
124Pheochromocytoma (HP:0002666)1.95249933
125Hyperacusis (HP:0010780)1.94497157
126Polyphagia (HP:0002591)1.93170759
127Prolonged QT interval (HP:0001657)1.90142888
128Generalized hypotonia (HP:0001290)1.88233400
129Muscular hypotonia of the trunk (HP:0008936)1.88041005
130Hepatoblastoma (HP:0002884)1.86539070
131Agitation (HP:0000713)1.86035331
132Abnormality of salivation (HP:0100755)1.85722126
133Rigidity (HP:0002063)1.85569295
134Hip dysplasia (HP:0001385)1.83105186
135Gait ataxia (HP:0002066)1.82431029
136Apathy (HP:0000741)1.81340717
137Rapidly progressive (HP:0003678)1.78933232
138Lower limb asymmetry (HP:0100559)1.77709834
139Psychosis (HP:0000709)1.77469772
140Broad foot (HP:0001769)1.76511553
141Decreased testicular size (HP:0008734)1.75141309
142Atrophy/Degeneration involving motor neurons (HP:0007373)1.74540665
143Specific learning disability (HP:0001328)1.74250074
144Protruding tongue (HP:0010808)1.74158342
145Akinesia (HP:0002304)1.73848303
146Abnormality of the periventricular white matter (HP:0002518)1.72259863
147Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.70491012

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA44.88926587
2MAP3K94.29768183
3NTRK33.95830271
4BCR3.16672733
5MARK13.11365793
6MAP3K42.69188164
7MINK12.58798134
8NTRK22.40934027
9DAPK22.37064464
10PAK62.30421393
11PRKD32.29732280
12KSR22.25569441
13EPHA32.17529939
14CAMKK12.17087768
15MAP2K72.01951385
16TRIM282.01609584
17NTRK11.98115127
18MAP4K21.79314656
19DYRK21.73900378
20CDK51.65766315
21TYRO31.62136021
22MAP2K41.60357941
23RIPK41.59773239
24KSR11.58440506
25STK381.57390598
26WNK31.53639338
27UHMK11.49279599
28CSNK1A1L1.48636850
29SIK21.48077327
30FES1.46969223
31DAPK11.41893388
32CSNK1G31.41767799
33TAOK11.40405669
34TNIK1.40252061
35PRPF4B1.35166322
36ARAF1.34332519
37PINK11.31254880
38MAP3K121.28743754
39MAP3K131.24073314
40ALK1.19202867
41LIMK11.17722968
42GRK51.14496622
43MAP3K21.13263665
44CAMKK21.13138641
45PRKCG1.11327664
46PHKG11.09023132
47PHKG21.09023132
48PRKCH1.08347181
49LATS21.08030097
50SIK31.02999858
51STK111.02840043
52CSNK1G11.00347309
53ICK0.99906169
54CDK150.98529131
55MAPK130.97651842
56CDK180.97431766
57CDK190.96259395
58TESK10.95603858
59PNCK0.95278084
60DYRK1B0.94436453
61NME10.94082333
62CDK140.93183742
63PLK20.91230267
64BCKDK0.88119450
65SGK4940.87738734
66SGK2230.87738734
67RIPK10.87164280
68CDK11A0.87081364
69TNK20.86454419
70BRD40.85474872
71CAMK10.85060138
72RPS6KA40.81924254
73CCNB10.81761041
74RAF10.81332906
75CAMK2A0.81160135
76MARK20.80100910
77PIM20.78498078
78ERBB30.78418576
79NEK10.77242828
80LMTK20.74989385
81RET0.74195029
82CAMK2B0.72039489
83SGK10.71444182
84SGK30.70685816
85SCYL20.67005694
86SGK20.63377838
87DDR20.62807053
88CDC42BPA0.62295744
89WNK10.61892785
90PDPK10.61467899
91PAK30.59526858
92PRKCZ0.59388654
93PDK10.59107776
94BRSK10.58906649
95NEK60.57846176
96RPS6KA30.57397975
97MAP3K10.56670308
98CSNK1G20.56156750
99FYN0.54223381
100CASK0.53479466
101PRKAA10.53395501
102DYRK1A0.52645110
103MAPK100.52356446
104CAMK2G0.51498594
105PKN10.50489241
106BRAF0.50075105
107CSNK1D0.50040075
108MAP3K60.49472583
109STK38L0.49172901
110SRPK10.48295833
111TESK20.46684844
112BMX0.45358541
113DAPK30.45163703
114PRKD20.44813246
115BMPR20.44188741
116CAMK40.43630162
117OXSR10.43416735
118CAMK2D0.42883807
119CSNK1A10.41789032
120MAP3K50.40697574
121PRKACA0.40647785
122PTK2B0.38449221
123PRKCE0.37834303
124PDGFRA0.36746619
125INSRR0.36475445
126FGR0.36396193
127MAPK120.34255281
128CAMK1G0.34031564
129MAP2K10.33708265
130TSSK60.33593170
131PRKCB0.33476328
132PRKACB0.33232479
133WNK40.32410436
134MAPK80.31306001
135GRK70.30848379
136RPS6KA20.29848492
137CSNK1E0.29084695
138RPS6KA50.26962624

Predicted pathways (KEGG)

RankGene SetZ-score
1* Nicotine addiction_Homo sapiens_hsa050333.28580347
2* Synaptic vesicle cycle_Homo sapiens_hsa047213.16171610
3Olfactory transduction_Homo sapiens_hsa047403.10702207
4* GABAergic synapse_Homo sapiens_hsa047272.90337089
5Circadian entrainment_Homo sapiens_hsa047132.65222246
6Glutamatergic synapse_Homo sapiens_hsa047242.56839487
7* Morphine addiction_Homo sapiens_hsa050322.55218823
8Long-term potentiation_Homo sapiens_hsa047202.52101430
9* Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.41295706
10Amphetamine addiction_Homo sapiens_hsa050312.40217762
11Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.24726882
12Dopaminergic synapse_Homo sapiens_hsa047282.20718904
13Salivary secretion_Homo sapiens_hsa049702.10067771
14Cocaine addiction_Homo sapiens_hsa050302.00558272
15Cholinergic synapse_Homo sapiens_hsa047251.99229412
16Gastric acid secretion_Homo sapiens_hsa049711.92093321
17Insulin secretion_Homo sapiens_hsa049111.85378333
18Aldosterone synthesis and secretion_Homo sapiens_hsa049251.78853972
19Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.73703589
20Nitrogen metabolism_Homo sapiens_hsa009101.69432798
21Long-term depression_Homo sapiens_hsa047301.68946640
22Renin secretion_Homo sapiens_hsa049241.64884583
23Oxytocin signaling pathway_Homo sapiens_hsa049211.63375849
24Taste transduction_Homo sapiens_hsa047421.61387372
25Serotonergic synapse_Homo sapiens_hsa047261.52084582
26Calcium signaling pathway_Homo sapiens_hsa040201.51382301
27Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.50320704
28Gap junction_Homo sapiens_hsa045401.49173726
29GnRH signaling pathway_Homo sapiens_hsa049121.43740600
30Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.39227771
31Oxidative phosphorylation_Homo sapiens_hsa001901.34032532
32Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.33509987
33cAMP signaling pathway_Homo sapiens_hsa040241.29347793
34Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.27713577
35Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.26884426
36Estrogen signaling pathway_Homo sapiens_hsa049151.15713446
37Type II diabetes mellitus_Homo sapiens_hsa049301.15209425
38Collecting duct acid secretion_Homo sapiens_hsa049661.11554888
39Glioma_Homo sapiens_hsa052141.10359862
40Phosphatidylinositol signaling system_Homo sapiens_hsa040701.07180746
41Parkinsons disease_Homo sapiens_hsa050121.03787212
42Cardiac muscle contraction_Homo sapiens_hsa042601.03399676
43Axon guidance_Homo sapiens_hsa043601.02543670
44ErbB signaling pathway_Homo sapiens_hsa040121.02439128
45Regulation of autophagy_Homo sapiens_hsa041400.99136566
46Melanogenesis_Homo sapiens_hsa049160.96491409
47beta-Alanine metabolism_Homo sapiens_hsa004100.95010210
48Phototransduction_Homo sapiens_hsa047440.94422200
49cGMP-PKG signaling pathway_Homo sapiens_hsa040220.94195839
50Oocyte meiosis_Homo sapiens_hsa041140.91322274
51Phospholipase D signaling pathway_Homo sapiens_hsa040720.89975776
52Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.89435846
53Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.89018736
54Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.87794644
55Type I diabetes mellitus_Homo sapiens_hsa049400.87013377
56Vascular smooth muscle contraction_Homo sapiens_hsa042700.84579448
57Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.83926493
58Dorso-ventral axis formation_Homo sapiens_hsa043200.83385165
59Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.81532508
60Alzheimers disease_Homo sapiens_hsa050100.81249238
61Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.80471180
62Thyroid hormone synthesis_Homo sapiens_hsa049180.79751565
63Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.77073865
64Pancreatic secretion_Homo sapiens_hsa049720.76959971
65Dilated cardiomyopathy_Homo sapiens_hsa054140.74300043
66MAPK signaling pathway_Homo sapiens_hsa040100.71087125
67Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.69243752
68Choline metabolism in cancer_Homo sapiens_hsa052310.69135938
69Alcoholism_Homo sapiens_hsa050340.67691636
70Vibrio cholerae infection_Homo sapiens_hsa051100.66770484
71Carbohydrate digestion and absorption_Homo sapiens_hsa049730.66083802
72Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.65372207
73Bile secretion_Homo sapiens_hsa049760.64566162
74mTOR signaling pathway_Homo sapiens_hsa041500.64168537
75Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.63629963
76Neurotrophin signaling pathway_Homo sapiens_hsa047220.63414981
77VEGF signaling pathway_Homo sapiens_hsa043700.61592572
78Rap1 signaling pathway_Homo sapiens_hsa040150.60892237
79Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.58903204
80Thyroid hormone signaling pathway_Homo sapiens_hsa049190.58705408
81Endocytosis_Homo sapiens_hsa041440.56210883
82Non-small cell lung cancer_Homo sapiens_hsa052230.55772982
83Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.55073318
84AMPK signaling pathway_Homo sapiens_hsa041520.54651672
85Selenocompound metabolism_Homo sapiens_hsa004500.54419446
86Huntingtons disease_Homo sapiens_hsa050160.54188774
87Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.53420279
88Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.53348085
89Ras signaling pathway_Homo sapiens_hsa040140.53326686
90Longevity regulating pathway - mammal_Homo sapiens_hsa042110.52576974
91Sphingolipid signaling pathway_Homo sapiens_hsa040710.52407437
92Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.52000102
93Butanoate metabolism_Homo sapiens_hsa006500.51475665
94Endometrial cancer_Homo sapiens_hsa052130.49422258
95Prion diseases_Homo sapiens_hsa050200.47676359
96Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.47381982
97Ether lipid metabolism_Homo sapiens_hsa005650.47069222
98Glucagon signaling pathway_Homo sapiens_hsa049220.46637397
99Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.46505354
100Chemokine signaling pathway_Homo sapiens_hsa040620.44021123
101Inositol phosphate metabolism_Homo sapiens_hsa005620.42211650
102Phagosome_Homo sapiens_hsa041450.41335096
103Circadian rhythm_Homo sapiens_hsa047100.41225117
104Insulin signaling pathway_Homo sapiens_hsa049100.41210404
105Renal cell carcinoma_Homo sapiens_hsa052110.40994169
106Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.40309909
107Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.39899529
108Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.39369440
109Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.39085952
110Steroid biosynthesis_Homo sapiens_hsa001000.38443461
111Arginine biosynthesis_Homo sapiens_hsa002200.37724997
112Cyanoamino acid metabolism_Homo sapiens_hsa004600.37593609
113Sulfur relay system_Homo sapiens_hsa041220.37307772
114Fatty acid biosynthesis_Homo sapiens_hsa000610.36912570
115Wnt signaling pathway_Homo sapiens_hsa043100.34052322
116Ovarian steroidogenesis_Homo sapiens_hsa049130.32980881
117Protein export_Homo sapiens_hsa030600.32773396
118Salmonella infection_Homo sapiens_hsa051320.30065598
119Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.29814074
120RNA polymerase_Homo sapiens_hsa030200.29098523
121Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.28181797
122Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.26981948
123Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.25453925
124Glycerophospholipid metabolism_Homo sapiens_hsa005640.24327481
125Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.22584607
126ABC transporters_Homo sapiens_hsa020100.22340324
127Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.21968968
128alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.21205784
129Shigellosis_Homo sapiens_hsa051310.20414320

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