SLC35D3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1negative regulation of appetite (GO:0032099)8.54801946
2negative regulation of response to food (GO:0032096)8.54801946
3negative regulation of heart rate (GO:0010459)8.18789868
4protein neddylation (GO:0045116)7.75344662
5Golgi transport vesicle coating (GO:0048200)7.47738868
6COPI coating of Golgi vesicle (GO:0048205)7.47738868
7protein maturation by protein folding (GO:0022417)6.65556779
8regulation of response to food (GO:0032095)6.20795218
9microtubule severing (GO:0051013)5.88351045
10adaptation of signaling pathway (GO:0023058)5.24160469
11regulation of appetite (GO:0032098)5.00668579
12thrombin receptor signaling pathway (GO:0070493)4.91668931
13negative regulation of heart contraction (GO:0045822)4.86944189
14endocrine pancreas development (GO:0031018)4.84975968
15positive regulation of gastrulation (GO:2000543)4.77886712
16maintenance of protein localization in endoplasmic reticulum (GO:0035437)4.75129550
17blood coagulation, intrinsic pathway (GO:0007597)4.71491128
18retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)4.50786539
19positive regulation of endothelial cell differentiation (GO:0045603)4.50720995
20pyrimidine deoxyribonucleotide catabolic process (GO:0009223)4.47205471
21antigen processing and presentation via MHC class Ib (GO:0002475)4.41170942
22regulation of type B pancreatic cell apoptotic process (GO:2000674)4.40321650
23regulation of cilium movement (GO:0003352)4.39220937
24neutrophil activation involved in immune response (GO:0002283)4.34555459
25protein retention in ER lumen (GO:0006621)4.30623339
26negative regulation of response to extracellular stimulus (GO:0032105)4.29574797
27negative regulation of response to nutrient levels (GO:0032108)4.29574797
28diaphragm development (GO:0060539)4.28258109
29triglyceride-rich lipoprotein particle remodeling (GO:0034370)4.21456202
30adenosine receptor signaling pathway (GO:0001973)4.17783551
31glandular epithelial cell differentiation (GO:0002067)4.15093476
32synaptic transmission, dopaminergic (GO:0001963)4.08233198
33regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:19022354.05049606
34negative regulation of blood circulation (GO:1903523)4.03872570
35positive regulation of insulin secretion (GO:0032024)3.99556799
36peptide hormone processing (GO:0016486)3.97328745
37negative regulation of neural precursor cell proliferation (GO:2000178)3.90807626
38signal peptide processing (GO:0006465)3.89784904
39adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)3.88784000
40skeletal muscle organ development (GO:0060538)3.87504910
41catecholamine transport (GO:0051937)3.85199856
42positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.84468825
43protein insertion into membrane (GO:0051205)3.82229033
44negative regulation of glycoprotein biosynthetic process (GO:0010561)3.79753811
45regulation of oxidative phosphorylation (GO:0002082)3.73525845
46pyrimidine nucleotide catabolic process (GO:0006244)3.73516368
47negative regulation of catecholamine secretion (GO:0033604)3.70732033
48negative regulation of thymocyte apoptotic process (GO:0070244)3.69985039
49negative regulation of hematopoietic progenitor cell differentiation (GO:1901533)3.69902254
50positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.69246022
51cell proliferation in forebrain (GO:0021846)3.67762389
52insulin secretion (GO:0030073)3.67601161
53regulation of insulin secretion (GO:0050796)3.64592161
54male genitalia development (GO:0030539)3.59363501
55regulation of norepinephrine secretion (GO:0014061)3.59278932
56polyamine biosynthetic process (GO:0006596)3.56225274
57negative regulation of macrophage differentiation (GO:0045650)3.54655056
58regulation of sensory perception (GO:0051931)3.52410085
59regulation of sensory perception of pain (GO:0051930)3.52410085
60detection of calcium ion (GO:0005513)3.50725260
61negative regulation of macrophage derived foam cell differentiation (GO:0010745)3.48487186
62dentate gyrus development (GO:0021542)3.46168466
63COPII vesicle coating (GO:0048208)3.46056229
64positive regulation of synaptic transmission, GABAergic (GO:0032230)3.43899575
65facial nerve structural organization (GO:0021612)3.42003142
66SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.41724001
67calcium ion import (GO:0070509)3.40398785
68monoamine transport (GO:0015844)3.39963572
69dopaminergic neuron differentiation (GO:0071542)3.39123435
70angiogenesis involved in wound healing (GO:0060055)3.38019763
71autophagic vacuole fusion (GO:0000046)3.37925990
72regulation of platelet activation (GO:0010543)3.37591881
73regulation of integrin-mediated signaling pathway (GO:2001044)3.37083910
74nitric oxide mediated signal transduction (GO:0007263)3.36878066
75positive regulation of peptide hormone secretion (GO:0090277)3.36378645
76regulation of peptide hormone secretion (GO:0090276)3.34623996
77protein targeting to ER (GO:0045047)3.34266728
78regulation of chromatin binding (GO:0035561)3.32955846
79cotranslational protein targeting to membrane (GO:0006613)3.32914812
80leukocyte migration involved in inflammatory response (GO:0002523)3.32458267
81antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.31164851
82antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)3.31164851
83sequestering of metal ion (GO:0051238)3.29302714
84regulation of meiosis I (GO:0060631)3.29110761
85dopamine biosynthetic process (GO:0042416)3.28984130
86platelet aggregation (GO:0070527)3.28392400
87regulation of peptide secretion (GO:0002791)3.28119000
88folic acid-containing compound biosynthetic process (GO:0009396)3.27077077
89pyrimidine deoxyribonucleotide metabolic process (GO:0009219)3.27020893
90positive regulation of peptide secretion (GO:0002793)3.26207110
91negative chemotaxis (GO:0050919)3.23997742
92vesicle coating (GO:0006901)3.22798702
93phenol-containing compound catabolic process (GO:0019336)3.22677103
94positive regulation of cAMP-mediated signaling (GO:0043950)3.22472376
95regulation of lipoprotein metabolic process (GO:0050746)3.22117793
96establishment of protein localization to endoplasmic reticulum (GO:0072599)3.21908800
97synaptic vesicle maturation (GO:0016188)3.21612527
98striatum development (GO:0021756)3.20204508
99tonic smooth muscle contraction (GO:0014820)3.19736692
100DNA deamination (GO:0045006)3.19050809
101regulation of platelet aggregation (GO:0090330)3.18126059
102negative regulation of norepinephrine secretion (GO:0010700)3.16951347
103protein localization to endoplasmic reticulum (GO:0070972)3.15740209
104type B pancreatic cell development (GO:0003323)3.14145890
105toxin metabolic process (GO:0009404)3.12785489
106beta-amyloid metabolic process (GO:0050435)3.12323238
107glandular epithelial cell development (GO:0002068)3.12303882
108negative regulation of cytosolic calcium ion concentration (GO:0051481)3.08050909
109myelination in peripheral nervous system (GO:0022011)3.07993250
110peripheral nervous system axon ensheathment (GO:0032292)3.07993250
111regulation of microtubule-based movement (GO:0060632)3.05729393
112catecholamine biosynthetic process (GO:0042423)3.05425075
113catechol-containing compound biosynthetic process (GO:0009713)3.05425075
114regulation of autophagic vacuole assembly (GO:2000785)3.02926664
115regulation of catecholamine metabolic process (GO:0042069)3.02880349
116regulation of dopamine metabolic process (GO:0042053)3.02880349
117activation of signaling protein activity involved in unfolded protein response (GO:0006987)3.01659989
118pteridine-containing compound biosynthetic process (GO:0042559)3.01526386
119cerebellar Purkinje cell layer development (GO:0021680)3.00445176
120low-density lipoprotein particle remodeling (GO:0034374)2.99924661
121negative regulation of phosphoprotein phosphatase activity (GO:0032515)2.99126275
122response to amphetamine (GO:0001975)2.97901957
123auditory receptor cell differentiation (GO:0042491)2.97522601
124regulation of cAMP-dependent protein kinase activity (GO:2000479)2.97299647
125positive regulation of nuclease activity (GO:0032075)2.95032257
126regulation of endothelial cell differentiation (GO:0045601)2.93312878
127cellular response to glucagon stimulus (GO:0071377)2.92610070
128deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.91768383
129regulation of dopamine uptake involved in synaptic transmission (GO:0051584)2.87195641
130regulation of catecholamine uptake involved in synaptic transmission (GO:0051940)2.87195641
131phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)2.86936255
132negative regulation of insulin secretion (GO:0046676)2.86006063
133olfactory bulb development (GO:0021772)2.85722163
134spinal cord development (GO:0021510)2.85138291
135early endosome to late endosome transport (GO:0045022)2.85119501
136negative regulation of organelle assembly (GO:1902116)2.85095211
137heart valve formation (GO:0003188)2.84798178
138GDP-mannose metabolic process (GO:0019673)2.84704293
139dopamine metabolic process (GO:0042417)2.84607374
140prepulse inhibition (GO:0060134)2.84485936
141negative regulation of platelet activation (GO:0010544)2.82318859
142regulation of hormone secretion (GO:0046883)2.81979200
143respiratory chain complex IV assembly (GO:0008535)2.80172806
144cellular biogenic amine biosynthetic process (GO:0042401)2.80071017
145generation of neurons (GO:0048699)2.78621950
146regulation of synaptic vesicle exocytosis (GO:2000300)2.78544531
147serotonin metabolic process (GO:0042428)2.78020617
148negative regulation of homotypic cell-cell adhesion (GO:0034111)2.77684456
149neuron maturation (GO:0042551)2.77632595
150positive regulation of mast cell activation (GO:0033005)2.77408483
151positive regulation of neurotransmitter transport (GO:0051590)2.76633697
152reproductive system development (GO:0061458)2.75620566
153norepinephrine metabolic process (GO:0042415)2.74887347
154dopamine receptor signaling pathway (GO:0007212)2.74688883
155peristalsis (GO:0030432)2.74385818
156negative regulation of transcription elongation from RNA polymerase II promoter (GO:0034244)2.74256504
157regulation of peptide transport (GO:0090087)2.73615032
158neuronal action potential propagation (GO:0019227)2.73382834
159radial glial cell differentiation (GO:0060019)2.73221377
160artery smooth muscle contraction (GO:0014824)2.72078805
161positive regulation of triglyceride biosynthetic process (GO:0010867)2.69774310
162oligodendrocyte development (GO:0014003)2.68820841
163regulation of synapse structural plasticity (GO:0051823)2.68457267
164protein N-linked glycosylation via asparagine (GO:0018279)2.67810432
165exocrine pancreas development (GO:0031017)2.67709390
166activation of transmembrane receptor protein tyrosine kinase activity (GO:0007171)2.67092382
167negative regulation of glycoprotein metabolic process (GO:1903019)2.66507418
168regulation of nuclease activity (GO:0032069)2.65359292
169negative regulation of histone acetylation (GO:0035067)2.64839928
170lipoxygenase pathway (GO:0019372)2.64134630
171peptidyl-asparagine modification (GO:0018196)2.63356642
172regulation of Golgi to plasma membrane protein transport (GO:0042996)2.63317255
173ER overload response (GO:0006983)2.62923875
174cellular zinc ion homeostasis (GO:0006882)2.62440287
175fusion of sperm to egg plasma membrane (GO:0007342)2.62046411
176lymphoid progenitor cell differentiation (GO:0002320)2.61601583
177negative regulation of neurotransmitter transport (GO:0051589)2.61301189
178ER-associated ubiquitin-dependent protein catabolic process (GO:0030433)2.61164261
179establishment of integrated proviral latency (GO:0075713)2.58225907
180behavioral response to nicotine (GO:0035095)2.57921049
181negative regulation of transcription regulatory region DNA binding (GO:2000678)2.57472165
182dopamine transport (GO:0015872)2.56318831
183primary amino compound metabolic process (GO:1901160)2.55831815
184Arp2/3 complex-mediated actin nucleation (GO:0034314)2.55587134
185ER to Golgi vesicle-mediated transport (GO:0006888)2.55429368
186intra-Golgi vesicle-mediated transport (GO:0006891)2.55115398

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse6.34468637
2GATA1_22025678_ChIP-Seq_K562_Human3.41225420
3HTT_18923047_ChIP-ChIP_STHdh_Human3.32076915
4* SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human3.11952393
5PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.94512575
6DMRT1_21621532_ChIP-ChIP_FETAL_Ovary2.90796338
7HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.72931008
8ELF1_17652178_ChIP-ChIP_JURKAT_Human2.67228080
9EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.65769856
10* RARB_27405468_Chip-Seq_BRAIN_Mouse2.63577472
11NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.59843103
12MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.57162997
13NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.43342612
14NOTCH1_21737748_ChIP-Seq_TLL_Human2.37648408
15RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.36274161
16* TAL1_20887958_ChIP-Seq_HPC-7_Mouse2.28200086
17LYL1_20887958_ChIP-Seq_HPC-7_Mouse2.26747195
18MYC_22102868_ChIP-Seq_BL_Human2.23194653
19POU5F1_16153702_ChIP-ChIP_HESCs_Human2.19252904
20GATA1_19941826_ChIP-Seq_K562_Human2.18747410
21GABP_17652178_ChIP-ChIP_JURKAT_Human2.18057846
22CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human2.17138247
23GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human2.11104400
24JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.07638603
25* BMI1_23680149_ChIP-Seq_NPCS_Mouse2.06086692
26* EZH2_27304074_Chip-Seq_ESCs_Mouse2.05404772
27CIITA_25753668_ChIP-Seq_RAJI_Human2.04765044
28GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.04426510
29PHC1_16625203_ChIP-ChIP_MESCs_Mouse2.03918278
30ERG_20887958_ChIP-Seq_HPC-7_Mouse2.03497904
31TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat10.5712919
32SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.97720058
33HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.97404257
34FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.95024221
35SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.94680410
36* JARID2_20064375_ChIP-Seq_MESCs_Mouse1.94076170
37* SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.92683212
38CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.92563192
39KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.89898815
40SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.88811806
41REST_21632747_ChIP-Seq_MESCs_Mouse1.88340350
42GATA1_19941827_ChIP-Seq_MEL_Mouse1.87877335
43EED_16625203_ChIP-ChIP_MESCs_Mouse1.85629876
44REST_18959480_ChIP-ChIP_MESCs_Mouse1.82217166
45EZH2_22144423_ChIP-Seq_EOC_Human1.78083914
46RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.76726774
47EST1_17652178_ChIP-ChIP_JURKAT_Human1.74992428
48ETS1_20019798_ChIP-Seq_JURKAT_Human1.70003678
49SUZ12_27294783_Chip-Seq_ESCs_Mouse1.69929340
50MYC_18555785_ChIP-Seq_MESCs_Mouse1.69894717
51* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.69555364
52CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.68390498
53RNF2_27304074_Chip-Seq_NSC_Mouse1.65895043
54* SCL_19346495_ChIP-Seq_HPC-7_Human1.64417285
55ZFX_18555785_ChIP-Seq_MESCs_Mouse1.61459368
56THAP11_20581084_ChIP-Seq_MESCs_Mouse1.60963861
57VDR_21846776_ChIP-Seq_THP-1_Human1.59295860
58* JARID2_20075857_ChIP-Seq_MESCs_Mouse1.58804890
59MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.56583020
60GATA2_19941826_ChIP-Seq_K562_Human1.56370322
61LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.55281546
62* SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.54676729
63MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.53904934
64* RNF2_18974828_ChIP-Seq_MESCs_Mouse1.52666077
65* EZH2_18974828_ChIP-Seq_MESCs_Mouse1.52666077
66FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.50946743
67* MTF2_20144788_ChIP-Seq_MESCs_Mouse1.49286307
68SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.48092702
69CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.47045603
70GABP_19822575_ChIP-Seq_HepG2_Human1.45745086
71VDR_23849224_ChIP-Seq_CD4+_Human1.44768459
72XRN2_22483619_ChIP-Seq_HELA_Human1.44461962
73SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.43199752
74MYC_18358816_ChIP-ChIP_MESCs_Mouse1.41267078
75EZH2_27294783_Chip-Seq_ESCs_Mouse1.40776371
76IGF1R_20145208_ChIP-Seq_DFB_Human1.38148530
77PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.37574632
78TFEB_21752829_ChIP-Seq_HELA_Human1.37542327
79* ERG_21242973_ChIP-ChIP_JURKAT_Human1.36502683
80PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.36235556
81FOXP3_21729870_ChIP-Seq_TREG_Human1.33091734
82CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.32501932
83OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.31576880
84CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.31417261
85GATA1_19941827_ChIP-Seq_MEL86_Mouse1.31029542
86E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.30477122
87TAF15_26573619_Chip-Seq_HEK293_Human1.30177523
88CTCF_18555785_ChIP-Seq_MESCs_Mouse1.27859275
89CBX2_27304074_Chip-Seq_ESCs_Mouse1.27661257
90VDR_24763502_ChIP-Seq_THP-1_Human1.27492714
91IRF8_22096565_ChIP-ChIP_GC-B_Human1.26571822
92TTF2_22483619_ChIP-Seq_HELA_Human1.26169899
93TCF7_22412390_ChIP-Seq_EML_Mouse1.24721887
94TET1_21451524_ChIP-Seq_MESCs_Mouse1.24073646
95* SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.23762351
96IKZF1_21737484_ChIP-ChIP_HCT116_Human1.23317144
97* TP53_20018659_ChIP-ChIP_R1E_Mouse1.23257224
98DNAJC2_21179169_ChIP-ChIP_NT2_Human1.23205558
99GATA1_22383799_ChIP-Seq_G1ME_Mouse1.21434704
100* RING1B_27294783_Chip-Seq_ESCs_Mouse1.21250183
101DROSHA_22980978_ChIP-Seq_HELA_Human1.21065759
102HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.20947826
103BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.20320212
104REST_19997604_ChIP-ChIP_NEURONS_Mouse1.20031118
105KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse1.19086753
106TRIM28_19339689_ChIP-ChIP_MESCs_Mouse1.18676623
107GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.18410825
108SPI1_23127762_ChIP-Seq_K562_Human1.17007462
109CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.13000428
110CDX2_19796622_ChIP-Seq_MESCs_Mouse1.12892008
111GF1B_26923725_Chip-Seq_HPCs_Mouse1.11076708
112CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.10509977
113SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.09893547
114* RNF2_27304074_Chip-Seq_ESCs_Mouse1.09709984
115FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.07444304
116UTX_26944678_Chip-Seq_JUKART_Human1.06895979
117* LXR_22292898_ChIP-Seq_THP-1_Human1.06785851
118CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.06611260
119CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.04497652
120STAT3_19079543_ChIP-ChIP_MESCs_Mouse1.04064001
121TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.03023332
122POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.03023332
123SMAD4_21799915_ChIP-Seq_A2780_Human1.02703821
124* ETS1_22383799_ChIP-Seq_G1ME_Mouse1.02456294
125TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.02032626
126PU.1_20513432_ChIP-Seq_Bcells_Mouse1.01675203
127* RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.00584142
128ELF1_20517297_ChIP-Seq_JURKAT_Human0.98356388
129POU3F2_20337985_ChIP-ChIP_501MEL_Human0.97765639
130HOXB4_20404135_ChIP-ChIP_EML_Mouse0.97043198
131TCF4_18268006_ChIP-ChIP_LS174T_Human0.96981162
132E2F1_18555785_ChIP-Seq_MESCs_Mouse0.96970941
133CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.96773054
134CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.95974671
135SOX2_16153702_ChIP-ChIP_HESCs_Human0.95711223
136* SUZ12_20075857_ChIP-Seq_MESCs_Mouse0.95553262
137MYC_19079543_ChIP-ChIP_MESCs_Mouse0.95302547
138SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.94779335
139NR3C1_23031785_ChIP-Seq_PC12_Mouse0.93886354
140SRY_22984422_ChIP-ChIP_TESTIS_Rat0.92779079
141SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.91782324
142SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human0.91430935
143DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.91046468
144THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.90100591
145ERG_20517297_ChIP-Seq_VCAP_Human0.90004087
146GATA3_27048872_Chip-Seq_THYMUS_Human0.89980181
147RCOR3_21632747_ChIP-Seq_MESCs_Mouse0.89931505
148ETV2_25802403_ChIP-Seq_MESCs_Mouse0.88769215
149VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human0.88495922
150EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.87762860
151ZIC3_20872845_ChIP-ChIP_MESCs_Mouse0.87684563
152GF1_26923725_Chip-Seq_HPCs_Mouse0.87634829
153SPI1_23547873_ChIP-Seq_NB4_Human0.87533347
154TDRD3_21172665_ChIP-Seq_MCF-7_Human0.86996367
155TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.84119752
156CTBP1_25329375_ChIP-Seq_LNCAP_Human0.82614255
157RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.82611470
158PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.82493250
159STAT6_21828071_ChIP-Seq_BEAS2B_Human0.81829905
160OCT1_27270436_Chip-Seq_PROSTATE_Human0.79270380
161KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.79166554
162KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.79166554
163KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.79166554
164PCGF2_27294783_Chip-Seq_NPCs_Mouse0.78941007
165KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.78136899
166* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.77995369
167TCF3_18347094_ChIP-ChIP_MESCs_Mouse0.77616733
168P53_22387025_ChIP-Seq_ESCs_Mouse0.77104282
169* RING1B_27294783_Chip-Seq_NPCs_Mouse0.77020582
170IRF1_19129219_ChIP-ChIP_H3396_Human0.76152598
171EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse0.75573407
172RUNX1_26923725_Chip-Seq_HPCs_Mouse0.74727911
173STAT1_20625510_ChIP-Seq_HELA_Human0.73264166
174UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.72762248
175ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.72478383
176OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.71135459
177TBL1_22424771_ChIP-Seq_293T_Human0.70753013
178NANOG_20526341_ChIP-Seq_ESCs_Human0.70324032
179MYC_18940864_ChIP-ChIP_HL60_Human0.69936729

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002822_catalepsy6.19184550
2* MP0005464_abnormal_platelet_physiology5.82162864
3MP0002909_abnormal_adrenal_gland4.53420501
4MP0002638_abnormal_pupillary_reflex3.42948061
5MP0003183_abnormal_peptide_metabolism3.35942675
6MP0002693_abnormal_pancreas_physiology3.24019850
7MP0002653_abnormal_ependyma_morphology3.22056256
8MP0003283_abnormal_digestive_organ3.19837346
9MP0002877_abnormal_melanocyte_morpholog3.19317956
10MP0010386_abnormal_urinary_bladder3.15903176
11MP0008004_abnormal_stomach_pH3.07084754
12MP0000013_abnormal_adipose_tissue2.92183981
13MP0001944_abnormal_pancreas_morphology2.89544937
14MP0005379_endocrine/exocrine_gland_phen2.83678012
15MP0002102_abnormal_ear_morphology2.79904173
16MP0004043_abnormal_pH_regulation2.69775825
17MP0001485_abnormal_pinna_reflex2.68500561
18MP0004859_abnormal_synaptic_plasticity2.45005921
19MP0003172_abnormal_lysosome_physiology2.38751031
20MP0003890_abnormal_embryonic-extraembry2.32494109
21MP0009780_abnormal_chondrocyte_physiolo2.23631509
22MP0001986_abnormal_taste_sensitivity2.11302618
23MP0004510_myositis2.09369718
24MP0002837_dystrophic_cardiac_calcinosis2.04326451
25MP0001529_abnormal_vocalization2.03101006
26MP0005646_abnormal_pituitary_gland2.02031068
27MP0003635_abnormal_synaptic_transmissio1.99401959
28MP0003942_abnormal_urinary_system1.94944784
29MP0004270_analgesia1.88848301
30MP0008789_abnormal_olfactory_epithelium1.88055253
31MP0005220_abnormal_exocrine_pancreas1.84068868
32MP0008961_abnormal_basal_metabolism1.83933277
33MP0005083_abnormal_biliary_tract1.79166791
34MP0002736_abnormal_nociception_after1.71546788
35MP0003567_abnormal_fetal_cardiomyocyte1.68332903
36MP0003866_abnormal_defecation1.63156473
37MP0009745_abnormal_behavioral_response1.62616840
38MP0002078_abnormal_glucose_homeostasis1.62396495
39MP0001905_abnormal_dopamine_level1.59834076
40MP0008872_abnormal_physiological_respon1.59341002
41MP0001727_abnormal_embryo_implantation1.58826894
42MP0005645_abnormal_hypothalamus_physiol1.54870097
43MP0006072_abnormal_retinal_apoptosis1.51148550
44MP0000678_abnormal_parathyroid_gland1.50267158
45MP0002063_abnormal_learning/memory/cond1.45092018
46MP0001188_hyperpigmentation1.42674635
47MP0002733_abnormal_thermal_nociception1.42271661
48MP0002572_abnormal_emotion/affect_behav1.41624015
49MP0001765_abnormal_ion_homeostasis1.39872533
50MP0005535_abnormal_body_temperature1.38642139
51MP0002396_abnormal_hematopoietic_system1.38607666
52MP0000003_abnormal_adipose_tissue1.36412614
53MP0002751_abnormal_autonomic_nervous1.35614078
54MP0002272_abnormal_nervous_system1.35531896
55MP0003868_abnormal_feces_composition1.33937985
56MP0003122_maternal_imprinting1.31055584
57MP0005409_darkened_coat_color1.25807119
58MP0002064_seizures1.23000492
59MP0003638_abnormal_response/metabolism_1.22894975
60MP0001970_abnormal_pain_threshold1.22467725
61MP0001879_abnormal_lymphatic_vessel1.20568876
62MP0000778_abnormal_nervous_system1.20078930
63MP0000534_abnormal_ureter_morphology1.19322027
64MP0004264_abnormal_extraembryonic_tissu1.18411111
65MP0000631_abnormal_neuroendocrine_gland1.17730741
66MP0004130_abnormal_muscle_cell1.17484024
67MP0002734_abnormal_mechanical_nocicepti1.16784925
68* MP0003953_abnormal_hormone_level1.14110364
69MP0001502_abnormal_circadian_rhythm1.13316944
70MP0009053_abnormal_anal_canal1.13173710
71MP0003011_delayed_dark_adaptation1.12808421
72MP0005058_abnormal_lysosome_morphology1.10762453
73MP0004924_abnormal_behavior1.10741860
74MP0005386_behavior/neurological_phenoty1.10741860
75MP0003195_calcinosis1.10531321
76MP0003959_abnormal_lean_body1.10077034
77MP0002184_abnormal_innervation1.09853664
78MP0002557_abnormal_social/conspecific_i1.08690176
79MP0006054_spinal_hemorrhage1.06693263
80MP0003724_increased_susceptibility_to1.06425883
81MP0003787_abnormal_imprinting1.04707532
82MP0002163_abnormal_gland_morphology1.04018402
83MP0001919_abnormal_reproductive_system1.03761456
84MP0008260_abnormal_autophagy1.03515504
85MP0008775_abnormal_heart_ventricle1.01741313
86MP0005174_abnormal_tail_pigmentation1.00728019
87MP0008877_abnormal_DNA_methylation0.98991553
88MP0004134_abnormal_chest_morphology0.98231738
89MP0004084_abnormal_cardiac_muscle0.96142031
90MP0005195_abnormal_posterior_eye0.95728117
91MP0004811_abnormal_neuron_physiology0.95559109
92MP0001348_abnormal_lacrimal_gland0.93803942
93MP0006276_abnormal_autonomic_nervous0.92902263
94MP0001664_abnormal_digestion0.92586304
95MP0005551_abnormal_eye_electrophysiolog0.91686569
96MP0005448_abnormal_energy_balance0.91541007
97MP0003121_genomic_imprinting0.91532502
98MP0006292_abnormal_olfactory_placode0.91205683
99MP0001501_abnormal_sleep_pattern0.90920803
100MP0008569_lethality_at_weaning0.89915022
101MP0001968_abnormal_touch/_nociception0.89900158
102MP0004036_abnormal_muscle_relaxation0.89886760
103MP0005636_abnormal_mineral_homeostasis0.89612608
104MP0003300_gastrointestinal_ulcer0.88739358
105MP0003879_abnormal_hair_cell0.87198573
106MP0002876_abnormal_thyroid_physiology0.86456306
107MP0000230_abnormal_systemic_arterial0.86399466
108MP0000383_abnormal_hair_follicle0.86163601
109MP0006036_abnormal_mitochondrial_physio0.82669471
110MP0008932_abnormal_embryonic_tissue0.82402726
111MP0000049_abnormal_middle_ear0.82260560
112MP0005187_abnormal_penis_morphology0.82073682
113MP0002069_abnormal_eating/drinking_beha0.81774258
114MP0000955_abnormal_spinal_cord0.81710868
115MP0003632_abnormal_nervous_system0.81678355
116MP0001756_abnormal_urination0.79871285
117MP0001270_distended_abdomen0.78676418
118MP0000639_abnormal_adrenal_gland0.77421726
119MP0008007_abnormal_cellular_replicative0.77197108
120MP0002234_abnormal_pharynx_morphology0.76562544
121MP0000613_abnormal_salivary_gland0.76507430
122MP0005394_taste/olfaction_phenotype0.76129650
123MP0005499_abnormal_olfactory_system0.76129650
124MP0003385_abnormal_body_wall0.76087503
125MP0005084_abnormal_gallbladder_morpholo0.75331162
126MP0000538_abnormal_urinary_bladder0.75162010
127MP0003693_abnormal_embryo_hatching0.74077803
128MP0001440_abnormal_grooming_behavior0.73863241
129MP0010329_abnormal_lipoprotein_level0.73314835
130MP0003633_abnormal_nervous_system0.73067773
131MP0010307_abnormal_tumor_latency0.72726622
132MP0001963_abnormal_hearing_physiology0.71845917
133MP0001299_abnormal_eye_distance/0.71796501
134MP0005381_digestive/alimentary_phenotyp0.71688338
135MP0005423_abnormal_somatic_nervous0.68175242
136MP0003566_abnormal_cell_adhesion0.68141665
137MP0001663_abnormal_digestive_system0.67986821
138MP0001293_anophthalmia0.67493644
139MP0009046_muscle_twitch0.66415163
140MP0001486_abnormal_startle_reflex0.66389914
141MP0002066_abnormal_motor_capabilities/c0.66122649
142MP0002067_abnormal_sensory_capabilities0.65445048
143MP0005253_abnormal_eye_physiology0.65358864
144MP0004085_abnormal_heartbeat0.65329673
145MP0003119_abnormal_digestive_system0.65210091
146MP0002928_abnormal_bile_duct0.64856153
147MP0009643_abnormal_urine_homeostasis0.64109056
148MP0009379_abnormal_foot_pigmentation0.63454467
149MP0003123_paternal_imprinting0.62172325
150MP0005367_renal/urinary_system_phenotyp0.61766716
151MP0000516_abnormal_urinary_system0.61766716
152MP0000465_gastrointestinal_hemorrhage0.61703116
153MP0000477_abnormal_intestine_morphology0.59942519
154MP0004142_abnormal_muscle_tone0.59705396
155MP0002095_abnormal_skin_pigmentation0.59522107
156MP0005503_abnormal_tendon_morphology0.58325697
157MP0001286_abnormal_eye_development0.57727598
158MP0002882_abnormal_neuron_morphology0.57120902

Predicted human phenotypes

RankGene SetZ-score
1Prolonged bleeding time (HP:0003010)7.59880109
2Menorrhagia (HP:0000132)7.28128776
3Increased mean platelet volume (HP:0011877)7.11876242
4Abnormal platelet volume (HP:0011876)6.58385820
5Petechiae (HP:0000967)6.46268017
6Purpura (HP:0000979)6.13483784
7Elevated circulating parathyroid hormone (PTH) level (HP:0003165)5.91869702
8Neonatal hypoglycemia (HP:0001998)5.70713720
9Hypothermia (HP:0002045)5.64734226
10Aplastic anemia (HP:0001915)5.27035172
11Hyperinsulinemic hypoglycemia (HP:0000825)5.12031538
12Hypoglycemic seizures (HP:0002173)4.88447247
13Epistaxis (HP:0000421)4.71800509
14Limb hypertonia (HP:0002509)4.50029631
15Symptomatic seizures (HP:0011145)4.25940723
16Hyperlipoproteinemia (HP:0010980)4.20829585
17Gingival bleeding (HP:0000225)4.08583065
18Visual hallucinations (HP:0002367)4.07167920
19Menstrual irregularities (HP:0000858)3.86993630
20Abnormality of calcium-phosphate metabolism (HP:0100530)3.78616674
21Acute lymphatic leukemia (HP:0006721)3.76832519
22Hypoglycemic coma (HP:0001325)3.62058873
23Mucopolysacchariduria (HP:0008155)3.52944009
24Urinary glycosaminoglycan excretion (HP:0003541)3.52944009
25Decreased circulating renin level (HP:0003351)3.51456010
26Abnormal platelet function (HP:0011869)3.49349800
27Impaired platelet aggregation (HP:0003540)3.49349800
28Parkinsonism with favorable response to dopaminergic medication (HP:0002548)3.40508039
29Dysostosis multiplex (HP:0000943)3.35085448
30Late onset (HP:0003584)3.34412524
31Hyperthyroidism (HP:0000836)3.33823540
32Spontaneous hematomas (HP:0007420)3.31766041
33Hepatoblastoma (HP:0002884)3.27390801
34Truncal obesity (HP:0001956)3.20323771
35Abnormality of polysaccharide metabolism (HP:0011012)3.16411527
36Abnormality of glycosaminoglycan metabolism (HP:0004371)3.16411527
37Abnormality of mucopolysaccharide metabolism (HP:0011020)3.16411527
38Progressive neurologic deterioration (HP:0002344)3.14211865
39Metaphyseal dysplasia (HP:0100255)3.13088635
40Papilledema (HP:0001085)3.00395578
41Polygenic inheritance (HP:0010982)2.97548570
42Limb dystonia (HP:0002451)2.93489327
43Agitation (HP:0000713)2.88548511
44Abnormal glycosylation (HP:0012345)2.87043191
45Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.87043191
46Abnormal protein N-linked glycosylation (HP:0012347)2.87043191
47Abnormal protein glycosylation (HP:0012346)2.87043191
48Abnormality of the pancreatic islet cells (HP:0006476)2.82399632
49Abnormality of endocrine pancreas physiology (HP:0012093)2.82399632
50Large for gestational age (HP:0001520)2.80964173
513-Methylglutaconic aciduria (HP:0003535)2.78754764
52Pancreatic islet-cell hyperplasia (HP:0004510)2.78228967
53Restlessness (HP:0000711)2.75825225
54Gait imbalance (HP:0002141)2.73842482
55Impulsivity (HP:0100710)2.69929396
56Neoplasm of the adrenal cortex (HP:0100641)2.69267373
57Ketoacidosis (HP:0001993)2.68997706
58Anxiety (HP:0000739)2.67996982
59Hypophosphatemic rickets (HP:0004912)2.67610846
60Diastasis recti (HP:0001540)2.66819411
61Insulin-resistant diabetes mellitus (HP:0000831)2.65576841
62Orthostatic hypotension (HP:0001278)2.63836947
63Type I transferrin isoform profile (HP:0003642)2.62619418
64Septate vagina (HP:0001153)2.61734051
65Cortical dysplasia (HP:0002539)2.61521055
66Depression (HP:0000716)2.60042381
67Conjunctival telangiectasia (HP:0000524)2.56413436
68Mesangial abnormality (HP:0001966)2.54441014
69Myokymia (HP:0002411)2.52642129
70Rectovaginal fistula (HP:0000143)2.49120048
71Rectal fistula (HP:0100590)2.49120048
72Type II lissencephaly (HP:0007260)2.48684131
73Generalized aminoaciduria (HP:0002909)2.46793283
74Nephrogenic diabetes insipidus (HP:0009806)2.46714093
75Increased density of long bones (HP:0006392)2.45918274
76Deep palmar crease (HP:0006191)2.41648576
77Acanthocytosis (HP:0001927)2.37782543
78Hyperglycemia (HP:0003074)2.36430378
79Hyperparathyroidism (HP:0000843)2.36064344
80Germ cell neoplasia (HP:0100728)2.35731916
81Pigmentary retinal degeneration (HP:0001146)2.34990731
82Anomalous pulmonary venous return (HP:0010772)2.34970181
83Poikilocytosis (HP:0004447)2.32707296
84Broad face (HP:0000283)2.32497849
85Muscular hypotonia of the trunk (HP:0008936)2.32391615
86Growth hormone excess (HP:0000845)2.32291114
87Abnormality of the common coagulation pathway (HP:0010990)2.30817000
88Prominent metopic ridge (HP:0005487)2.30474386
89Hypercortisolism (HP:0001578)2.28389614
90Dyschromatopsia (HP:0007641)2.27853263
91Medial flaring of the eyebrow (HP:0010747)2.26368153
92Unilateral renal agenesis (HP:0000122)2.24603636
93Chronic otitis media (HP:0000389)2.24451548
94Poor coordination (HP:0002370)2.24115989
95Insulin resistance (HP:0000855)2.23907513
96Abnormality of aromatic amino acid family metabolism (HP:0004338)2.23850998
97Congenital primary aphakia (HP:0007707)2.21915847
98Overgrowth (HP:0001548)2.21548496
99Retinal atrophy (HP:0001105)2.20353466
100Paralysis (HP:0003470)2.20012367
101Chronic bronchitis (HP:0004469)2.19600491
102Intestinal atresia (HP:0011100)2.17025032
103Hypotension (HP:0002615)2.16512711
104Hypokalemia (HP:0002900)2.15108040
105Abnormality of the parathyroid morphology (HP:0011766)2.14911183
106Abnormal pancreas size (HP:0012094)2.12539184
107Intestinal fistula (HP:0100819)2.11468339
108Generalized hyperpigmentation (HP:0007440)2.11303930
109Thrombocytosis (HP:0001894)2.09960293
110Polyphagia (HP:0002591)2.08344334
11111 pairs of ribs (HP:0000878)2.08037686
112Focal motor seizures (HP:0011153)2.07900003
113Abnormality of lateral ventricle (HP:0030047)2.07871418
114Arthropathy (HP:0003040)2.07786540
115EEG with generalized epileptiform discharges (HP:0011198)2.07652850
116Severe visual impairment (HP:0001141)2.07101801
117Hypsarrhythmia (HP:0002521)2.06874006
118Abnormality of renin-angiotensin system (HP:0000847)2.06677949
119Progressive muscle weakness (HP:0003323)2.06226644
120Abnormality of the vasculature of the conjunctiva (HP:0008054)2.03888399
121Cortical visual impairment (HP:0100704)2.03452451
122Spinal canal stenosis (HP:0003416)2.03077660
123Transitional cell carcinoma of the bladder (HP:0006740)2.02936428
124Amblyopia (HP:0000646)2.01760218
125Failure to thrive in infancy (HP:0001531)2.01653104
126Ventricular fibrillation (HP:0001663)1.98854062
127Upper limb muscle weakness (HP:0003484)1.98094830
128Epileptiform EEG discharges (HP:0011182)1.96741867
129Abnormality of the pulmonary veins (HP:0011718)1.95746239
130Vaginal fistula (HP:0004320)1.95657316
131Bruising susceptibility (HP:0000978)1.93653922
132Hypoplastic left heart (HP:0004383)1.93508968
133Porencephaly (HP:0002132)1.92879198
134Volvulus (HP:0002580)1.92632223
135Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.91906657
136Abnormal delayed hypersensitivity skin test (HP:0002963)1.91768348
137Abnormal autonomic nervous system physiology (HP:0012332)1.90641117
138Adrenal hypoplasia (HP:0000835)1.90355381
139Hepatic necrosis (HP:0002605)1.87863256
140Abnormality of the heme biosynthetic pathway (HP:0010472)1.86780425
141Bronchitis (HP:0012387)1.85439923
142Hyperkalemia (HP:0002153)1.85149794
143Bladder carcinoma (HP:0002862)1.84370113
144Bladder neoplasm (HP:0009725)1.84370113
145IgM deficiency (HP:0002850)1.83136160
146Poor eye contact (HP:0000817)1.83088773
147Abnormal pupillary function (HP:0007686)1.82971690
148Torticollis (HP:0000473)1.82595335
149Absent rod-and cone-mediated responses on ERG (HP:0007688)1.82186150
150Disproportionate short-trunk short stature (HP:0003521)1.81837546
151Retinal dysplasia (HP:0007973)1.78984010
152Abnormality of the metopic suture (HP:0005556)1.78940395
153Resting tremor (HP:0002322)1.78485898
154Craniofacial dystonia (HP:0012179)1.77921048
155Neuroendocrine neoplasm (HP:0100634)1.77228757
156Tongue fasciculations (HP:0001308)1.76911839
157Abnormality of potassium homeostasis (HP:0011042)1.76044786
158Hepatocellular necrosis (HP:0001404)1.74487863
159Severe short stature (HP:0003510)1.74399602
160Decreased central vision (HP:0007663)1.73498046
161Vaginal atresia (HP:0000148)1.73140309
162Dysautonomia (HP:0002459)1.72998419
163Proximal tubulopathy (HP:0000114)1.71574135
164Uterine leiomyosarcoma (HP:0002891)1.71381833
165Leiomyosarcoma (HP:0100243)1.71381833
166Impaired smooth pursuit (HP:0007772)1.71341083
167Adrenal overactivity (HP:0002717)1.70909506
168Testicular neoplasm (HP:0010788)1.69949713
169Colon cancer (HP:0003003)1.69389636
170Focal dystonia (HP:0004373)1.68972667
171Pheochromocytoma (HP:0002666)1.68853697
172Genital tract atresia (HP:0001827)1.68739437
173Osteomalacia (HP:0002749)1.68230647
174Thyroid carcinoma (HP:0002890)1.67925034
175Episodic fever (HP:0001954)1.66785750
176Abnormality of the lower motor neuron (HP:0002366)1.66461863
177Neurodegeneration (HP:0002180)1.64763086
178Hyperphosphatemia (HP:0002905)1.64151838

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FLT35.31255387
2PASK4.48739288
3INSRR4.29225226
4NLK4.21920029
5MAPK153.79114825
6SCYL23.50355426
7ADRBK22.90560839
8EPHA32.87915817
9KIT2.84125023
10HIPK22.67531028
11STK32.53201184
12PNCK2.21837348
13EIF2AK12.21165611
14NTRK32.19588990
15BMX2.06564878
16MAP3K21.94034601
17TNIK1.81849722
18TAOK31.81094232
19MST41.80977010
20CAMKK21.79879965
21EPHA41.69022502
22NTRK11.68724802
23PRKD31.66985027
24TEC1.60816926
25NME21.54642938
26BRAF1.49642075
27UHMK11.48269827
28MYLK1.45098882
29DYRK31.42510632
30PHKG11.40727997
31PHKG21.40727997
32FES1.39951935
33CDC71.29186172
34CAMKK11.28420565
35BTK1.27699858
36ARAF1.27555632
37CAMK1G1.27101046
38CSF1R1.25942979
39ILK1.20155911
40MAP2K21.13938446
41PLK21.13572320
42STK161.10955406
43DYRK21.09481511
44DAPK11.09285778
45MINK11.07646936
46MAP3K11.07383987
47PTK2B1.07040480
48PIK3CG1.06889882
49GRK71.05046269
50MARK11.04663333
51IRAK21.01595343
52MAPKAPK51.01158677
53IRAK40.99384556
54BMPR20.97336293
55KSR20.96198244
56DAPK20.96140956
57WNK40.95591885
58SYK0.95471756
59STK40.95130642
60BRSK20.92492316
61PRKD20.88834866
62DYRK1B0.87734802
63SIK30.87602592
64ALK0.87232954
65WNK30.87173367
66TRIB30.85229902
67ITK0.84713659
68CDK190.83803080
69CDK50.81271145
70TIE10.79613866
71MAP4K10.79575288
72PAK10.75960040
73SGK20.74948587
74CASK0.72972671
75RIPK10.72493841
76PDGFRA0.69606374
77CDC42BPA0.68832123
78CSNK1G30.68821761
79ABL20.68280180
80DAPK30.68146853
81HCK0.66140650
82MUSK0.64916189
83CAMK10.64601601
84TSSK60.63868717
85PRKCH0.63475620
86BRSK10.62089055
87PRKCG0.62020683
88VRK10.61689905
89ADRBK10.60696221
90MARK20.60477523
91PRKAA10.57868494
92NUAK10.56991325
93RAF10.56977865
94TRIM280.56323309
95MAPK130.55790699
96IRAK10.55752964
97CSNK1G20.54851055
98MATK0.54787325
99SIK20.53641208
100MOS0.52520174
101PKN10.52207890
102MAPKAPK30.51296636
103EPHB20.50719219
104CDK30.50651623
105DMPK0.50310039
106EIF2AK20.49645857
107RET0.49620756
108NTRK20.48892926
109BCKDK0.47882289
110TBK10.47746372
111FRK0.46920933
112ZAK0.46751147
113EEF2K0.45899406
114CSNK1A1L0.44809460
115PKN20.44238717
116JAK30.43354662
117PDPK10.42460443
118RPS6KA20.41341429
119MAP3K90.41324455
120MAP2K70.41139664
121BMPR1B0.40351107
122AURKA0.40229245
123PDK10.39006100
124ZAP700.38694842
125LATS10.38126489
126GRK60.36023180
127ERBB20.35933613
128SGK30.35844257
129IRAK30.35478478
130WEE10.35018252
131CSNK1G10.34699872
132MAP3K50.34650423
133PLK30.34151149
134RIPK40.34088614
135PTK60.33414378
136STK110.33084251
137CAMK1D0.32366547
138PRKCA0.32356668
139CHEK20.31924250
140PAK20.31622670
141PLK40.31483912
142CSNK1D0.31003480
143MAP3K60.30842874
144PRKACA0.30262810
145FGR0.29273084
146FER0.29039377
147NEK10.28971992
148CSNK1A10.28722909
149SGK2230.27680315
150SGK4940.27680315
151PRKG10.26667310
152MAP2K10.25618009
153TRPM70.25587351
154LYN0.24585155
155GRK50.24406742
156JAK20.23954050
157KSR10.23103360
158DYRK1A0.23040287
159PTK20.22861694
160PRKACG0.22374349
161PRKCI0.22203863
162PRKCE0.21744430
163MARK30.21541239
164PIM20.21348699

Predicted pathways (KEGG)

RankGene SetZ-score
1Maturity onset diabetes of the young_Homo sapiens_hsa049506.91318573
2Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006035.15389382
3Protein export_Homo sapiens_hsa030604.43554288
4Cocaine addiction_Homo sapiens_hsa050303.32059759
5Insulin secretion_Homo sapiens_hsa049112.91716863
6Type I diabetes mellitus_Homo sapiens_hsa049402.71353800
7Pathogenic Escherichia coli infection_Homo sapiens_hsa051302.50590000
8Amphetamine addiction_Homo sapiens_hsa050312.49847321
9Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007602.32586794
10Protein processing in endoplasmic reticulum_Homo sapiens_hsa041412.16291531
11Vibrio cholerae infection_Homo sapiens_hsa051102.15238583
12N-Glycan biosynthesis_Homo sapiens_hsa005102.00101455
13Dopaminergic synapse_Homo sapiens_hsa047281.92490270
14Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.86596299
15Synaptic vesicle cycle_Homo sapiens_hsa047211.70186741
16Circadian entrainment_Homo sapiens_hsa047131.63237407
17Notch signaling pathway_Homo sapiens_hsa043301.60805934
18Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.59310893
19Aldosterone synthesis and secretion_Homo sapiens_hsa049251.54564099
20Olfactory transduction_Homo sapiens_hsa047401.53979981
21Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.51608990
22Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.50130889
23Long-term potentiation_Homo sapiens_hsa047201.47820981
24SNARE interactions in vesicular transport_Homo sapiens_hsa041301.46335582
25Alcoholism_Homo sapiens_hsa050341.45516816
26Morphine addiction_Homo sapiens_hsa050321.45097096
27Cholinergic synapse_Homo sapiens_hsa047251.43739494
28Glycosaminoglycan degradation_Homo sapiens_hsa005311.41188100
29Sulfur metabolism_Homo sapiens_hsa009201.36357889
30Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.35769499
31Type II diabetes mellitus_Homo sapiens_hsa049301.31528425
32Serotonergic synapse_Homo sapiens_hsa047261.31066589
33GABAergic synapse_Homo sapiens_hsa047271.30920178
34Non-homologous end-joining_Homo sapiens_hsa034501.30635158
35Thyroid cancer_Homo sapiens_hsa052161.24497962
36DNA replication_Homo sapiens_hsa030301.24297943
37Ribosome_Homo sapiens_hsa030101.24034887
38Taste transduction_Homo sapiens_hsa047421.22337879
39Renin secretion_Homo sapiens_hsa049241.16825910
40Folate biosynthesis_Homo sapiens_hsa007901.16456612
41ECM-receptor interaction_Homo sapiens_hsa045121.16211147
42Arachidonic acid metabolism_Homo sapiens_hsa005901.15501913
43Carbohydrate digestion and absorption_Homo sapiens_hsa049731.14737673
44Nitrogen metabolism_Homo sapiens_hsa009101.11574960
45Axon guidance_Homo sapiens_hsa043601.09221390
46Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.08679728
47Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.02843947
48Endometrial cancer_Homo sapiens_hsa052131.01309186
49Endocytosis_Homo sapiens_hsa041440.96895583
50Chemokine signaling pathway_Homo sapiens_hsa040620.95711359
51Phototransduction_Homo sapiens_hsa047440.94765028
52Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.94312245
53Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.93243373
54Selenocompound metabolism_Homo sapiens_hsa004500.92170267
55Phospholipase D signaling pathway_Homo sapiens_hsa040720.91535529
56Thyroid hormone synthesis_Homo sapiens_hsa049180.89950715
57Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.89021209
58Parkinsons disease_Homo sapiens_hsa050120.87760524
59Dorso-ventral axis formation_Homo sapiens_hsa043200.86005198
60Other glycan degradation_Homo sapiens_hsa005110.84568032
61Glutamatergic synapse_Homo sapiens_hsa047240.84506162
62Dilated cardiomyopathy_Homo sapiens_hsa054140.84481005
63alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.83818366
64Mismatch repair_Homo sapiens_hsa034300.82631055
65Gap junction_Homo sapiens_hsa045400.82216613
66Long-term depression_Homo sapiens_hsa047300.80470201
67Purine metabolism_Homo sapiens_hsa002300.80253055
68Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.79888944
69Estrogen signaling pathway_Homo sapiens_hsa049150.79061508
70Ovarian steroidogenesis_Homo sapiens_hsa049130.78797478
71Pancreatic secretion_Homo sapiens_hsa049720.75963968
72Vascular smooth muscle contraction_Homo sapiens_hsa042700.75739050
73Glucagon signaling pathway_Homo sapiens_hsa049220.73807806
74Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.73168564
75Collecting duct acid secretion_Homo sapiens_hsa049660.73090502
76cAMP signaling pathway_Homo sapiens_hsa040240.72270136
77Lysosome_Homo sapiens_hsa041420.71353889
78Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.68868568
79Regulation of autophagy_Homo sapiens_hsa041400.67574575
80Colorectal cancer_Homo sapiens_hsa052100.67217208
81Gastric acid secretion_Homo sapiens_hsa049710.66959666
82Hematopoietic cell lineage_Homo sapiens_hsa046400.66249565
83Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.65553285
84Ras signaling pathway_Homo sapiens_hsa040140.64682074
85Circadian rhythm_Homo sapiens_hsa047100.64292878
86Adipocytokine signaling pathway_Homo sapiens_hsa049200.62604160
87Rap1 signaling pathway_Homo sapiens_hsa040150.59556542
88Regulation of actin cytoskeleton_Homo sapiens_hsa048100.58326637
89Oxytocin signaling pathway_Homo sapiens_hsa049210.58099597
90Salivary secretion_Homo sapiens_hsa049700.57212266
91Adherens junction_Homo sapiens_hsa045200.56350059
92Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.56116447
93Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.55724773
94Prostate cancer_Homo sapiens_hsa052150.55316596
95Calcium signaling pathway_Homo sapiens_hsa040200.54960803
96Platelet activation_Homo sapiens_hsa046110.54916300
97Choline metabolism in cancer_Homo sapiens_hsa052310.54800979
98cGMP-PKG signaling pathway_Homo sapiens_hsa040220.54728474
99Prolactin signaling pathway_Homo sapiens_hsa049170.54334989
100Base excision repair_Homo sapiens_hsa034100.51501470
101Melanoma_Homo sapiens_hsa052180.51419425
102Pyrimidine metabolism_Homo sapiens_hsa002400.51223251
103Neurotrophin signaling pathway_Homo sapiens_hsa047220.51102008
104Non-small cell lung cancer_Homo sapiens_hsa052230.50950043
105Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.50495150
106Glutathione metabolism_Homo sapiens_hsa004800.50184007
107B cell receptor signaling pathway_Homo sapiens_hsa046620.49819818
108Phagosome_Homo sapiens_hsa041450.49231281
109Wnt signaling pathway_Homo sapiens_hsa043100.49123185
110GnRH signaling pathway_Homo sapiens_hsa049120.48988776
111Melanogenesis_Homo sapiens_hsa049160.48662567
112Phosphatidylinositol signaling system_Homo sapiens_hsa040700.47929820
113Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.47557162
114Starch and sucrose metabolism_Homo sapiens_hsa005000.47460072
115MAPK signaling pathway_Homo sapiens_hsa040100.46741474
116Antigen processing and presentation_Homo sapiens_hsa046120.46321375
117Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.45962641
118Hedgehog signaling pathway_Homo sapiens_hsa043400.45875196
119Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.43678980
120FoxO signaling pathway_Homo sapiens_hsa040680.43053743
121beta-Alanine metabolism_Homo sapiens_hsa004100.42412750
122Alzheimers disease_Homo sapiens_hsa050100.42273959
123Central carbon metabolism in cancer_Homo sapiens_hsa052300.42137046
124Sphingolipid metabolism_Homo sapiens_hsa006000.42030854
125Prion diseases_Homo sapiens_hsa050200.41734449
126Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.41273592
127Galactose metabolism_Homo sapiens_hsa000520.40680836
128Steroid biosynthesis_Homo sapiens_hsa001000.40581958
129AMPK signaling pathway_Homo sapiens_hsa041520.40489842
130ABC transporters_Homo sapiens_hsa020100.39219122
131Legionellosis_Homo sapiens_hsa051340.37854446
132Acute myeloid leukemia_Homo sapiens_hsa052210.34631957
133Oxidative phosphorylation_Homo sapiens_hsa001900.32613312
134Oocyte meiosis_Homo sapiens_hsa041140.31666465
135RNA degradation_Homo sapiens_hsa030180.31480305
136Spliceosome_Homo sapiens_hsa030400.29544851
137Insulin resistance_Homo sapiens_hsa049310.28462116
138Phenylalanine metabolism_Homo sapiens_hsa003600.28327499
139African trypanosomiasis_Homo sapiens_hsa051430.28217491
140Thyroid hormone signaling pathway_Homo sapiens_hsa049190.28014989
141Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.27054630
142Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.26997245
143Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.26781086
144Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.26342147
145Insulin signaling pathway_Homo sapiens_hsa049100.25974257
146Homologous recombination_Homo sapiens_hsa034400.25829009
147Glioma_Homo sapiens_hsa052140.23968566
148RNA polymerase_Homo sapiens_hsa030200.22991775

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »