SLC35F1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neuron cell-cell adhesion (GO:0007158)5.86448648
2vocalization behavior (GO:0071625)5.69941359
3regulation of short-term neuronal synaptic plasticity (GO:0048172)5.58392814
4locomotory exploration behavior (GO:0035641)5.28897964
5regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.28195905
6synaptic vesicle exocytosis (GO:0016079)5.17931854
7positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.14821277
8positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.06173374
9synaptic vesicle maturation (GO:0016188)5.04445061
10layer formation in cerebral cortex (GO:0021819)5.01788180
11protein localization to synapse (GO:0035418)4.94557327
12regulation of glutamate receptor signaling pathway (GO:1900449)4.84325519
13righting reflex (GO:0060013)4.79649404
14glutamate secretion (GO:0014047)4.61517251
15neuron recognition (GO:0008038)4.56878918
16dendritic spine morphogenesis (GO:0060997)4.54855678
17exploration behavior (GO:0035640)4.50784248
18regulation of synaptic vesicle exocytosis (GO:2000300)4.49057623
19ionotropic glutamate receptor signaling pathway (GO:0035235)4.45358574
20regulation of synapse structural plasticity (GO:0051823)4.36493679
21nonmotile primary cilium assembly (GO:0035058)4.20386916
22postsynaptic membrane organization (GO:0001941)4.13458698
23glutamate receptor signaling pathway (GO:0007215)4.08454677
24pyrimidine nucleobase catabolic process (GO:0006208)4.07697989
25axonal fasciculation (GO:0007413)4.06987573
26regulation of long-term neuronal synaptic plasticity (GO:0048169)4.04584594
27neurotransmitter secretion (GO:0007269)4.03101531
28limb bud formation (GO:0060174)3.97924584
29regulation of synaptic vesicle transport (GO:1902803)3.94406300
30regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.94201382
31regulation of neuronal synaptic plasticity (GO:0048168)3.92971065
32regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.92861888
33neurotransmitter-gated ion channel clustering (GO:0072578)3.92678913
34synaptic transmission, glutamatergic (GO:0035249)3.90034282
35transmission of nerve impulse (GO:0019226)3.87356353
36regulation of DNA endoreduplication (GO:0032875)3.85836609
37presynaptic membrane assembly (GO:0097105)3.83823977
38replication fork processing (GO:0031297)3.82873728
39neuronal action potential propagation (GO:0019227)3.82748143
40synaptic vesicle docking involved in exocytosis (GO:0016081)3.82467365
41dendrite morphogenesis (GO:0048813)3.79767733
42neuron-neuron synaptic transmission (GO:0007270)3.78240800
43proline transport (GO:0015824)3.77458751
44prepulse inhibition (GO:0060134)3.71613905
45gamma-aminobutyric acid transport (GO:0015812)3.68165586
46cell migration in hindbrain (GO:0021535)3.66375737
47positive regulation of synapse maturation (GO:0090129)3.66320703
48central nervous system projection neuron axonogenesis (GO:0021952)3.64555237
49DNA double-strand break processing (GO:0000729)3.59239097
50auditory behavior (GO:0031223)3.58072885
51synapse assembly (GO:0007416)3.55802086
52membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.49894018
53regulation of excitatory postsynaptic membrane potential (GO:0060079)3.49294546
54presynaptic membrane organization (GO:0097090)3.48019513
55C4-dicarboxylate transport (GO:0015740)3.47146872
56resolution of meiotic recombination intermediates (GO:0000712)3.45444285
57positive regulation of membrane potential (GO:0045838)3.42283477
58long-term memory (GO:0007616)3.42002305
59regulation of postsynaptic membrane potential (GO:0060078)3.40986763
60regulation of dendritic spine morphogenesis (GO:0061001)3.40634693
61detection of mechanical stimulus involved in sensory perception of sound (GO:0050910)3.39417743
62innervation (GO:0060384)3.39110692
63nucleobase catabolic process (GO:0046113)3.38446207
64positive regulation of synapse assembly (GO:0051965)3.36488524
65regulation of synaptic transmission, glutamatergic (GO:0051966)3.35652066
66neurotransmitter transport (GO:0006836)3.34622877
67cerebral cortex radially oriented cell migration (GO:0021799)3.34389622
68positive regulation of synaptic transmission, GABAergic (GO:0032230)3.33958141
69positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.30776058
70response to auditory stimulus (GO:0010996)3.29376445
71regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.28813194
72synaptic vesicle endocytosis (GO:0048488)3.27986093
73histone H2A acetylation (GO:0043968)3.24502056
74gamma-aminobutyric acid signaling pathway (GO:0007214)3.24275967
75inner ear receptor stereocilium organization (GO:0060122)3.19226793
76long-term synaptic potentiation (GO:0060291)3.18245819
77olfactory bulb development (GO:0021772)3.17670333
78negative regulation of DNA-dependent DNA replication (GO:2000104)3.17512413
79maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.16245970
80regulation of synaptic plasticity (GO:0048167)3.15475042
81negative regulation of synaptic transmission, GABAergic (GO:0032229)3.14494881
82auditory receptor cell stereocilium organization (GO:0060088)3.14433995
83G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.14297487
84membrane hyperpolarization (GO:0060081)3.13859436
85synapse organization (GO:0050808)3.11757716
86startle response (GO:0001964)3.11566084
87dendrite development (GO:0016358)3.09886634
88regulation of neurotransmitter levels (GO:0001505)3.08411287
89neuronal ion channel clustering (GO:0045161)3.08356329
90negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.07732428
91regulation of vesicle fusion (GO:0031338)3.06488719
92learning (GO:0007612)3.06479472
93activation of protein kinase A activity (GO:0034199)3.05846679
94positive regulation of dendritic spine development (GO:0060999)3.04935677
95social behavior (GO:0035176)3.04355299
96intraspecies interaction between organisms (GO:0051703)3.04355299
97positive regulation of dendritic spine morphogenesis (GO:0061003)3.03148400
98regulation of neurotransmitter secretion (GO:0046928)3.02323176
99behavioral fear response (GO:0001662)3.01131031
100behavioral defense response (GO:0002209)3.01131031
101negative regulation of microtubule polymerization (GO:0031115)3.00608432
102dendritic spine organization (GO:0097061)3.00276622
103regulation of timing of cell differentiation (GO:0048505)2.98392979
104mechanosensory behavior (GO:0007638)2.98200410
105neuromuscular process controlling balance (GO:0050885)2.98017103
106positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.97370158
107cellular response to cholesterol (GO:0071397)2.97143421
108regulation of dendritic spine development (GO:0060998)2.96613534
109negative regulation of calcium ion-dependent exocytosis (GO:0045955)2.96455639
110membrane depolarization (GO:0051899)2.96296960
111cerebellar Purkinje cell layer development (GO:0021680)2.95409613
112regulation of synapse assembly (GO:0051963)2.95181000
113mating behavior (GO:0007617)2.94972516
114retinal ganglion cell axon guidance (GO:0031290)2.93751473
115response to histamine (GO:0034776)2.92877913
116regulation of synapse organization (GO:0050807)2.90325767
117response to pheromone (GO:0019236)2.89246758
118regulation of synapse maturation (GO:0090128)2.88783914
119platelet dense granule organization (GO:0060155)2.88022781
120cellular potassium ion homeostasis (GO:0030007)2.87273256
121cell communication by electrical coupling (GO:0010644)2.86934101
122forebrain neuron differentiation (GO:0021879)2.85417245
123intraciliary transport (GO:0042073)2.84903448
124oligodendrocyte differentiation (GO:0048709)2.84598852
125regulation of development, heterochronic (GO:0040034)2.84392700
126glycosphingolipid biosynthetic process (GO:0006688)2.83741786
127reflex (GO:0060004)2.81327561
128neurotransmitter uptake (GO:0001504)2.78949840
129adult walking behavior (GO:0007628)2.75982231
130appendage development (GO:0048736)2.74515385
131limb development (GO:0060173)2.74515385
132positive regulation of amino acid transport (GO:0051957)2.74323109
133kinetochore organization (GO:0051383)2.73989909
134cellular response to sterol (GO:0036315)2.72727998
135centriole replication (GO:0007099)2.72420858
136otic vesicle formation (GO:0030916)2.72071631
137membrane assembly (GO:0071709)2.71689286
138microtubule depolymerization (GO:0007019)2.69723450
139photoreceptor cell maintenance (GO:0045494)2.64322998
140negative regulation of DNA recombination (GO:0045910)2.61953272
141kinetochore assembly (GO:0051382)2.60825806
142regulation of respiratory system process (GO:0044065)2.53714577
143negative regulation of neurotransmitter transport (GO:0051589)2.52120314
144mitotic sister chromatid cohesion (GO:0007064)2.50903839
145spinal cord development (GO:0021510)2.50198488
146negative regulation of translation, ncRNA-mediated (GO:0040033)2.47655666
147regulation of translation, ncRNA-mediated (GO:0045974)2.47655666
148negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.47655666
149translesion synthesis (GO:0019985)2.47504319
150cilium organization (GO:0044782)2.45576860
151cilium assembly (GO:0042384)2.45277114
152neural tube formation (GO:0001841)2.45051391
153detection of mechanical stimulus involved in sensory perception (GO:0050974)2.44278285
154negative regulation of dendrite development (GO:2000171)2.44245944
155sister chromatid segregation (GO:0000819)2.44175783
156somite development (GO:0061053)2.42966865
157chromatin remodeling at centromere (GO:0031055)2.41915716
158negative regulation of transcription regulatory region DNA binding (GO:2000678)2.41879909
159cilium morphogenesis (GO:0060271)2.41743519
160microtubule anchoring (GO:0034453)2.40162900
161regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.39706164
162cerebral cortex cell migration (GO:0021795)2.39110966
163DNA replication-dependent nucleosome assembly (GO:0006335)2.36900286
164DNA replication-dependent nucleosome organization (GO:0034723)2.36900286
165DNA damage response, detection of DNA damage (GO:0042769)2.36827036

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.90799460
2GBX2_23144817_ChIP-Seq_PC3_Human3.77587490
3SALL1_21062744_ChIP-ChIP_HESCs_Human3.64961925
4JARID2_20064375_ChIP-Seq_MESCs_Mouse3.10707110
5* SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.10199451
6* SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.96079960
7HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.87641878
8EZH2_27304074_Chip-Seq_ESCs_Mouse2.73320293
9RNF2_18974828_ChIP-Seq_MESCs_Mouse2.68254496
10EZH2_18974828_ChIP-Seq_MESCs_Mouse2.68254496
11JARID2_20075857_ChIP-Seq_MESCs_Mouse2.60234944
12* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.58425068
13* SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.56075140
14REST_21632747_ChIP-Seq_MESCs_Mouse2.55127568
15SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.49441555
16* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.39082307
17* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.38553329
18CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.37505427
19EED_16625203_ChIP-ChIP_MESCs_Mouse2.36147661
20GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.29331728
21* EWS_26573619_Chip-Seq_HEK293_Human2.29222237
22* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.27877957
23* EZH2_27294783_Chip-Seq_ESCs_Mouse2.24434941
24RNF2_27304074_Chip-Seq_ESCs_Mouse2.24317359
25AR_21572438_ChIP-Seq_LNCaP_Human2.23689809
26DROSHA_22980978_ChIP-Seq_HELA_Human2.18243237
27NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.15819667
28ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.15292661
29RBPJ_22232070_ChIP-Seq_NCS_Mouse2.10574126
30TAF15_26573619_Chip-Seq_HEK293_Human2.08173756
31RARB_27405468_Chip-Seq_BRAIN_Mouse2.07915077
32CTBP2_25329375_ChIP-Seq_LNCAP_Human2.02194258
33REST_18959480_ChIP-ChIP_MESCs_Mouse2.01079044
34MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.84649417
35CTBP1_25329375_ChIP-Seq_LNCAP_Human1.80528998
36VDR_22108803_ChIP-Seq_LS180_Human1.78859143
37MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.77284480
38IGF1R_20145208_ChIP-Seq_DFB_Human1.76582182
39IKZF1_21737484_ChIP-ChIP_HCT116_Human1.76329477
40* ZFP57_27257070_Chip-Seq_ESCs_Mouse1.73231997
41* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.71443309
42CBX2_27304074_Chip-Seq_ESCs_Mouse1.68255056
43ZNF274_21170338_ChIP-Seq_K562_Hela1.62335919
44* SMAD4_21799915_ChIP-Seq_A2780_Human1.60178928
45PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.58121986
46* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.57460799
47POU5F1_16153702_ChIP-ChIP_HESCs_Human1.57330349
48* RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.52544869
49EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.49066361
50P300_19829295_ChIP-Seq_ESCs_Human1.48741282
51MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.43910194
52BMI1_23680149_ChIP-Seq_NPCS_Mouse1.42266709
53SMAD3_21741376_ChIP-Seq_EPCs_Human1.40640763
54* KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.40168451
55RING1B_27294783_Chip-Seq_ESCs_Mouse1.40145399
56E2F4_17652178_ChIP-ChIP_JURKAT_Human1.40022762
57SOX9_26525672_Chip-Seq_HEART_Mouse1.39381249
58* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.38731182
59OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.38160733
60SOX2_21211035_ChIP-Seq_LN229_Gbm1.35001604
61RNF2_27304074_Chip-Seq_NSC_Mouse1.34573551
62FOXM1_23109430_ChIP-Seq_U2OS_Human1.34253931
63* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.33587534
64MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.32262529
65ERG_21242973_ChIP-ChIP_JURKAT_Human1.31684816
66PIAS1_25552417_ChIP-Seq_VCAP_Human1.30820996
67* TOP2B_26459242_ChIP-Seq_MCF-7_Human1.30714199
68AR_25329375_ChIP-Seq_VCAP_Human1.29193474
69STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.27916497
70* EZH2_27294783_Chip-Seq_NPCs_Mouse1.27635628
71POU3F2_20337985_ChIP-ChIP_501MEL_Human1.26188355
72IRF1_19129219_ChIP-ChIP_H3396_Human1.24659266
73FLI1_27457419_Chip-Seq_LIVER_Mouse1.24472851
74NR3C1_23031785_ChIP-Seq_PC12_Mouse1.23986082
75EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.23444682
76FUS_26573619_Chip-Seq_HEK293_Human1.23403245
77E2F7_22180533_ChIP-Seq_HELA_Human1.22038174
78* RING1B_27294783_Chip-Seq_NPCs_Mouse1.21730465
79* STAT3_23295773_ChIP-Seq_U87_Human1.20139831
80* AR_19668381_ChIP-Seq_PC3_Human1.17732995
81IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.17078771
82CBP_20019798_ChIP-Seq_JUKART_Human1.17078771
83LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.16458684
84CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.16458330
85SUZ12_27294783_Chip-Seq_NPCs_Mouse1.16100961
86GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.15962363
87TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.15920159
88P53_22127205_ChIP-Seq_FIBROBLAST_Human1.14721827
89TCF4_22108803_ChIP-Seq_LS180_Human1.14342279
90PCGF2_27294783_Chip-Seq_NPCs_Mouse1.13813052
91P53_22387025_ChIP-Seq_ESCs_Mouse1.13636457
92PCGF2_27294783_Chip-Seq_ESCs_Mouse1.13409241
93ARNT_22903824_ChIP-Seq_MCF-7_Human1.13346297
94AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.11206698
95* FLI1_21867929_ChIP-Seq_TH2_Mouse1.10783960
96KLF5_20875108_ChIP-Seq_MESCs_Mouse1.09760011
97AHR_22903824_ChIP-Seq_MCF-7_Human1.09144397
98* YAP1_20516196_ChIP-Seq_MESCs_Mouse1.08722787
99ZNF217_24962896_ChIP-Seq_MCF-7_Human1.08555579
100* SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.08536019
101RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.07701375
102TBX3_20139965_ChIP-Seq_ESCs_Mouse1.07423605
103TBX3_20139965_ChIP-Seq_MESCs_Mouse1.07355102
104UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.06898891
105* CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.05249031
106NR3C1_21868756_ChIP-Seq_MCF10A_Human1.05244045
107WT1_25993318_ChIP-Seq_PODOCYTE_Human1.04899075
108* TCF4_23295773_ChIP-Seq_U87_Human1.04795803
109CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.04789983
110CDX2_19796622_ChIP-Seq_MESCs_Mouse1.04765067
111ELK1_19687146_ChIP-ChIP_HELA_Human1.04603227
112TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.04400895
113* KDM2B_26808549_Chip-Seq_REH_Human1.04303207
114* RUNX2_22187159_ChIP-Seq_PCA_Human1.03812950
115CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.03670099
116SMAD_19615063_ChIP-ChIP_OVARY_Human1.03328223
117HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.00875622
118NFE2_27457419_Chip-Seq_LIVER_Mouse1.00757372
119TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.00356258
120* POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.00253840
121* TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.00253840
122MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.99635924
123* TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse0.98688958
124WT1_19549856_ChIP-ChIP_CCG9911_Human0.98544452
125SMAD3_21741376_ChIP-Seq_ESCs_Human0.98498264
126TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97587795
127ER_23166858_ChIP-Seq_MCF-7_Human0.96967225
128TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.95820167
129JUN_21703547_ChIP-Seq_K562_Human0.95622448
130PRDM14_20953172_ChIP-Seq_ESCs_Human0.93395467
131TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.92971986
132WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.92654283
133BCAT_22108803_ChIP-Seq_LS180_Human0.91389336
134DNAJC2_21179169_ChIP-ChIP_NT2_Human0.90566997
135TP53_18474530_ChIP-ChIP_U2OS_Human0.90073560
136SMAD4_21741376_ChIP-Seq_HESCs_Human0.89285399
137VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.88393537
138ZFP281_18757296_ChIP-ChIP_E14_Mouse0.87335858
139* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.87034627
140NANOG_18555785_Chip-Seq_ESCs_Mouse0.86173480
141TP53_16413492_ChIP-PET_HCT116_Human0.86117571

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.47288110
2MP0003880_abnormal_central_pattern4.95250406
3MP0003635_abnormal_synaptic_transmissio3.92144079
4MP0004270_analgesia3.52384035
5MP0005423_abnormal_somatic_nervous3.24483619
6MP0002063_abnormal_learning/memory/cond3.24159947
7MP0009745_abnormal_behavioral_response3.13701651
8MP0002064_seizures2.88426587
9MP0001968_abnormal_touch/_nociception2.85667372
10MP0002572_abnormal_emotion/affect_behav2.73127921
11MP0001486_abnormal_startle_reflex2.63145347
12MP0009046_muscle_twitch2.60038167
13MP0002734_abnormal_mechanical_nocicepti2.57849655
14MP0000778_abnormal_nervous_system2.47384589
15MP0006276_abnormal_autonomic_nervous2.33294061
16MP0002272_abnormal_nervous_system2.30796966
17MP0004147_increased_porphyrin_level2.26462816
18MP0001440_abnormal_grooming_behavior2.25714169
19MP0002736_abnormal_nociception_after2.14749331
20MP0001501_abnormal_sleep_pattern2.10575472
21MP0002822_catalepsy2.10413140
22MP0002735_abnormal_chemical_nociception2.09978835
23MP0002733_abnormal_thermal_nociception2.09392877
24MP0002184_abnormal_innervation2.08002266
25MP0002067_abnormal_sensory_capabilities2.01667193
26MP0002557_abnormal_social/conspecific_i1.98952380
27MP0001529_abnormal_vocalization1.93404076
28MP0001970_abnormal_pain_threshold1.88503926
29MP0005248_abnormal_Harderian_gland1.87790618
30MP0004924_abnormal_behavior1.79833134
31MP0005386_behavior/neurological_phenoty1.79833134
32MP0000516_abnormal_urinary_system1.77559731
33MP0005367_renal/urinary_system_phenotyp1.77559731
34MP0004811_abnormal_neuron_physiology1.76911538
35MP0003121_genomic_imprinting1.75084178
36MP0000569_abnormal_digit_pigmentation1.71169129
37MP0004858_abnormal_nervous_system1.71091513
38MP0001984_abnormal_olfaction1.70322528
39MP0008789_abnormal_olfactory_epithelium1.68766762
40MP0000955_abnormal_spinal_cord1.68503475
41MP0003329_amyloid_beta_deposits1.67040351
42MP0000049_abnormal_middle_ear1.62637896
43MP0005646_abnormal_pituitary_gland1.61000642
44MP0009780_abnormal_chondrocyte_physiolo1.57505737
45MP0002909_abnormal_adrenal_gland1.55909490
46MP0002882_abnormal_neuron_morphology1.53742867
47MP0002233_abnormal_nose_morphology1.53483409
48MP0008569_lethality_at_weaning1.52333556
49MP0003755_abnormal_palate_morphology1.52321652
50MP0005645_abnormal_hypothalamus_physiol1.49106228
51MP0010094_abnormal_chromosome_stability1.47391376
52MP0005253_abnormal_eye_physiology1.46531483
53MP0001905_abnormal_dopamine_level1.46260863
54MP0001502_abnormal_circadian_rhythm1.44140584
55MP0003122_maternal_imprinting1.43841196
56MP0004885_abnormal_endolymph1.42308104
57MP0002066_abnormal_motor_capabilities/c1.41400883
58MP0002938_white_spotting1.40777415
59MP0001188_hyperpigmentation1.39095197
60MP0008058_abnormal_DNA_repair1.37826304
61MP0003937_abnormal_limbs/digits/tail_de1.37627689
62MP0000566_synostosis1.34112003
63MP0004742_abnormal_vestibular_system1.30843727
64MP0004142_abnormal_muscle_tone1.29594029
65MP0003136_yellow_coat_color1.29054144
66MP0002152_abnormal_brain_morphology1.28894003
67MP0001293_anophthalmia1.27434445
68MP0003879_abnormal_hair_cell1.24544575
69MP0008877_abnormal_DNA_methylation1.23175615
70MP0000631_abnormal_neuroendocrine_gland1.19253714
71MP0005551_abnormal_eye_electrophysiolog1.16005822
72MP0003787_abnormal_imprinting1.07463161
73MP0005391_vision/eye_phenotype1.02865783
74MP0001986_abnormal_taste_sensitivity1.02542640
75MP0002653_abnormal_ependyma_morphology1.02014796
76MP0003634_abnormal_glial_cell0.99541324
77MP0003633_abnormal_nervous_system0.98137983
78MP0002638_abnormal_pupillary_reflex0.97255013
79MP0002752_abnormal_somatic_nervous0.96242357
80MP0002254_reproductive_system_inflammat0.95878067
81MP0001286_abnormal_eye_development0.94515918
82MP0002282_abnormal_trachea_morphology0.94266772
83MP0000751_myopathy0.94137994
84MP0005394_taste/olfaction_phenotype0.93291315
85MP0005499_abnormal_olfactory_system0.93291315
86MP0003631_nervous_system_phenotype0.93150342
87MP0003385_abnormal_body_wall0.92863729
88MP0002069_abnormal_eating/drinking_beha0.91614721
89MP0003861_abnormal_nervous_system0.90585593
90MP0002229_neurodegeneration0.89667313
91MP0003567_abnormal_fetal_cardiomyocyte0.89374980
92MP0003011_delayed_dark_adaptation0.89196721
93MP0003283_abnormal_digestive_organ0.89038384
94MP0001963_abnormal_hearing_physiology0.88937975
95MP0000647_abnormal_sebaceous_gland0.87768246
96MP0010386_abnormal_urinary_bladder0.86691439
97MP0004133_heterotaxia0.86461939
98MP0005195_abnormal_posterior_eye0.86344256
99MP0003935_abnormal_craniofacial_develop0.86161811
100MP0005409_darkened_coat_color0.85613994
101MP0004145_abnormal_muscle_electrophysio0.83601093
102MP0008961_abnormal_basal_metabolism0.83197375
103MP0002102_abnormal_ear_morphology0.81527308
104MP0001299_abnormal_eye_distance/0.81468504
105MP0001177_atelectasis0.81425951
106MP0002751_abnormal_autonomic_nervous0.81383730
107MP0004085_abnormal_heartbeat0.80234229
108MP0000427_abnormal_hair_cycle0.79770132
109MP0003632_abnormal_nervous_system0.79542326
110MP0002090_abnormal_vision0.77723975
111MP0003137_abnormal_impulse_conducting0.77186723
112MP0000920_abnormal_myelination0.76259383
113MP0005187_abnormal_penis_morphology0.74325084
114MP0001324_abnormal_eye_pigmentation0.74264100
115MP0000026_abnormal_inner_ear0.73222088
116MP0002249_abnormal_larynx_morphology0.73060461
117MP0006072_abnormal_retinal_apoptosis0.72925797
118MP0002697_abnormal_eye_size0.72529141
119MP0002837_dystrophic_cardiac_calcinosis0.72010346
120MP0009250_abnormal_appendicular_skeleto0.71983325
121MP0002095_abnormal_skin_pigmentation0.71956932
122MP0008872_abnormal_physiological_respon0.69126365
123MP0005535_abnormal_body_temperature0.66082706
124MP0001943_abnormal_respiration0.66033843
125MP0004233_abnormal_muscle_weight0.65878697
126MP0000534_abnormal_ureter_morphology0.65801439
127MP0006292_abnormal_olfactory_placode0.64592904
128MP0001485_abnormal_pinna_reflex0.61027158
129MP0005171_absent_coat_pigmentation0.60364620
130MP0002082_postnatal_lethality0.59800027
131MP0010770_preweaning_lethality0.59800027
132MP0003938_abnormal_ear_development0.59753408
133MP0000604_amyloidosis0.59571257
134MP0001664_abnormal_digestion0.59060062
135MP0010769_abnormal_survival0.57978677
136MP0002234_abnormal_pharynx_morphology0.57172436
137MP0000537_abnormal_urethra_morphology0.56625031

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.69700780
2Myokymia (HP:0002411)5.84505617
3Focal seizures (HP:0007359)5.19811493
4Visual hallucinations (HP:0002367)4.62705128
5Epileptic encephalopathy (HP:0200134)4.55526540
6Limb dystonia (HP:0002451)3.86025826
7Febrile seizures (HP:0002373)3.82507490
8Progressive cerebellar ataxia (HP:0002073)3.76568036
9Broad-based gait (HP:0002136)3.76008247
10Atonic seizures (HP:0010819)3.60619708
11Absence seizures (HP:0002121)3.50660621
12Hyperventilation (HP:0002883)3.44832329
13Generalized tonic-clonic seizures (HP:0002069)3.44672562
14Excessive salivation (HP:0003781)3.43857090
15Drooling (HP:0002307)3.43857090
16Mutism (HP:0002300)3.43125019
17True hermaphroditism (HP:0010459)3.41134498
18Supranuclear gaze palsy (HP:0000605)3.37871171
19Volvulus (HP:0002580)3.33125438
20Dialeptic seizures (HP:0011146)3.22411873
21Action tremor (HP:0002345)3.21000004
22Abnormality of the labia minora (HP:0012880)3.20285013
23Intestinal atresia (HP:0011100)3.17900043
24Poor eye contact (HP:0000817)3.11765360
25Ankle clonus (HP:0011448)3.10813085
26Colon cancer (HP:0003003)3.08086731
27Progressive inability to walk (HP:0002505)3.06825015
28Hemiparesis (HP:0001269)2.94780704
29Pancreatic fibrosis (HP:0100732)2.93462211
30Papilledema (HP:0001085)2.92217815
31Impaired social interactions (HP:0000735)2.91760443
32Abnormal social behavior (HP:0012433)2.91760443
33Truncal ataxia (HP:0002078)2.86166337
34Pancreatic cysts (HP:0001737)2.85910669
35Oligodactyly (hands) (HP:0001180)2.83865082
36Polyphagia (HP:0002591)2.81004229
37Amblyopia (HP:0000646)2.80735369
38Congenital sensorineural hearing impairment (HP:0008527)2.79158904
39Abnormal eating behavior (HP:0100738)2.75062703
40Depression (HP:0000716)2.73226045
41Astrocytoma (HP:0009592)2.72602104
42Abnormality of the astrocytes (HP:0100707)2.72602104
43Neurofibrillary tangles (HP:0002185)2.71115986
44Cerebral inclusion bodies (HP:0100314)2.69305039
45Absent speech (HP:0001344)2.67595283
46Epileptiform EEG discharges (HP:0011182)2.64802328
47Termporal pattern (HP:0011008)2.64321207
48Insidious onset (HP:0003587)2.64321207
49EEG with generalized epileptiform discharges (HP:0011198)2.62064154
50Hemiplegia (HP:0002301)2.60480001
51Akinesia (HP:0002304)2.60171767
52Anxiety (HP:0000739)2.58502448
53Impaired vibration sensation in the lower limbs (HP:0002166)2.57807471
54Abnormality of chromosome stability (HP:0003220)2.56826726
55Amyotrophic lateral sclerosis (HP:0007354)2.56531912
56Molar tooth sign on MRI (HP:0002419)2.56512014
57Abnormality of midbrain morphology (HP:0002418)2.56512014
58Dysdiadochokinesis (HP:0002075)2.55178341
59Aplasia/Hypoplasia of the sternum (HP:0006714)2.53821179
60Hypsarrhythmia (HP:0002521)2.52543440
61Meckel diverticulum (HP:0002245)2.52197107
62Gaze-evoked nystagmus (HP:0000640)2.50586326
63Urinary bladder sphincter dysfunction (HP:0002839)2.49490439
64Abnormality of the corticospinal tract (HP:0002492)2.48990731
65Abnormality of the ileum (HP:0001549)2.47217462
66Torticollis (HP:0000473)2.44992555
67Fetal akinesia sequence (HP:0001989)2.44207490
68Aplasia/Hypoplasia of the uvula (HP:0010293)2.42651335
69Inability to walk (HP:0002540)2.38930463
70Oligodactyly (HP:0012165)2.38896030
71Urinary urgency (HP:0000012)2.37829445
72Diplopia (HP:0000651)2.37666210
73Abnormality of binocular vision (HP:0011514)2.37666210
74Hypoplasia of the brainstem (HP:0002365)2.37220354
75Aplasia/Hypoplasia of the brainstem (HP:0007362)2.37220354
76Spastic gait (HP:0002064)2.36316645
77Hepatoblastoma (HP:0002884)2.34909910
78Genetic anticipation (HP:0003743)2.34627350
79Megalencephaly (HP:0001355)2.33374240
80Agitation (HP:0000713)2.32772941
81Pheochromocytoma (HP:0002666)2.32222410
82Nephronophthisis (HP:0000090)2.31410794
83Dysmetria (HP:0001310)2.31279515
84Renal hypoplasia (HP:0000089)2.29983026
85Abnormal lung lobation (HP:0002101)2.29946227
86Abnormality of salivation (HP:0100755)2.23966176
87Stereotypic behavior (HP:0000733)2.23486430
88Postural instability (HP:0002172)2.21361139
89Glioma (HP:0009733)2.20957761
90Abnormal sex determination (HP:0012244)2.20208569
91Sex reversal (HP:0012245)2.20208569
92Postaxial hand polydactyly (HP:0001162)2.19826331
93Split foot (HP:0001839)2.19514563
94Postaxial foot polydactyly (HP:0001830)2.18367665
95Focal dystonia (HP:0004373)2.18188357
96Ependymoma (HP:0002888)2.17172756
97Blue irides (HP:0000635)2.16468385
98Preaxial hand polydactyly (HP:0001177)2.16451181
99Vitreoretinal degeneration (HP:0000655)2.15267876
100Gastrointestinal atresia (HP:0002589)2.15183488
101Optic nerve hypoplasia (HP:0000609)2.12955680
102Protruding tongue (HP:0010808)2.12228905
103Lissencephaly (HP:0001339)2.11945361
104Narrow forehead (HP:0000341)2.11426561
105Inappropriate behavior (HP:0000719)2.10928311
106Medial flaring of the eyebrow (HP:0010747)2.10104104
107Aplasia/Hypoplasia of the tibia (HP:0005772)2.09451982
108Anencephaly (HP:0002323)2.08964568
109Obstructive sleep apnea (HP:0002870)2.08790558
110Septo-optic dysplasia (HP:0100842)2.07158125
111Neoplasm of the oral cavity (HP:0100649)2.06577204
112Bradykinesia (HP:0002067)2.06276404
113Sleep apnea (HP:0010535)2.05976104
114Long clavicles (HP:0000890)2.05691476
115Failure to thrive in infancy (HP:0001531)2.03108013
116Gait imbalance (HP:0002141)2.02230364
117Aplasia/Hypoplasia of the tongue (HP:0010295)2.01590175
118Exotropia (HP:0000577)2.00493693
119Craniofacial dystonia (HP:0012179)1.99548107
120Specific learning disability (HP:0001328)1.99174417
121Genital tract atresia (HP:0001827)1.98995916
122Astigmatism (HP:0000483)1.98292097
123Bifid tongue (HP:0010297)1.95642139
124Generalized myoclonic seizures (HP:0002123)1.93967695
125Congenital primary aphakia (HP:0007707)1.93449748
126Cystic liver disease (HP:0006706)1.93392111
127Hypoventilation (HP:0002791)1.92229869
128Abnormality of the renal medulla (HP:0100957)1.91814205
129Tented upper lip vermilion (HP:0010804)1.91463539
130Vaginal atresia (HP:0000148)1.90050428
131Esotropia (HP:0000565)1.89720763
132Neuroendocrine neoplasm (HP:0100634)1.89633337
133Pachygyria (HP:0001302)1.89512036
134Lower limb muscle weakness (HP:0007340)1.88278023
135Abnormality of the duodenum (HP:0002246)1.87596518
136Aqueductal stenosis (HP:0002410)1.87531165
137Short 4th metacarpal (HP:0010044)1.87500842
138Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)1.87500842
139Sporadic (HP:0003745)1.87267901
140Retinal dysplasia (HP:0007973)1.87016317
141Impaired smooth pursuit (HP:0007772)1.86902512
142Sloping forehead (HP:0000340)1.86336521
143Morphological abnormality of the pyramidal tract (HP:0002062)1.84021009
144Abolished electroretinogram (ERG) (HP:0000550)1.83828277
145Scanning speech (HP:0002168)1.83563893
146Chronic hepatic failure (HP:0100626)1.82399931
147Autism (HP:0000717)1.82141944
148Intention tremor (HP:0002080)1.81334974
149Gastroesophageal reflux (HP:0002020)1.80053424
150Abnormality of the lower motor neuron (HP:0002366)1.79961597
151Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.79350844
152Duodenal stenosis (HP:0100867)1.78449946
153Small intestinal stenosis (HP:0012848)1.78449946
154Type II lissencephaly (HP:0007260)1.77604846
155Male pseudohermaphroditism (HP:0000037)1.77290115
156Agnosia (HP:0010524)1.77237681
157Sclerocornea (HP:0000647)1.76695169
158Keratoconus (HP:0000563)1.74951035
159Increased corneal curvature (HP:0100692)1.74951035
160Hyperthyroidism (HP:0000836)1.74863285
161Congenital hepatic fibrosis (HP:0002612)1.74556603
162Cortical dysplasia (HP:0002539)1.74393394
163Abnormality of the ischium (HP:0003174)1.74218082
164Pendular nystagmus (HP:0012043)1.74001667
165Cupped ear (HP:0000378)1.73396206
166Narrow nasal bridge (HP:0000446)1.72944526
167Triphalangeal thumb (HP:0001199)1.72398665
168Medulloblastoma (HP:0002885)1.71072222
169Gait ataxia (HP:0002066)1.70987577
170Hypoplasia of the corpus callosum (HP:0002079)1.70809263
171Dyskinesia (HP:0100660)1.70778031
172Ulnar claw (HP:0001178)1.69357353
173Apathy (HP:0000741)1.69262187
174Abnormality of ocular smooth pursuit (HP:0000617)1.69148863
175Short tibia (HP:0005736)1.68808927
176Nephrogenic diabetes insipidus (HP:0009806)1.68766929

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK15.26976449
2NTRK33.74154513
3EPHA43.31259848
4MAP3K93.26359239
5WEE13.25865595
6MAP3K43.16380072
7CASK2.81540335
8MINK12.77447507
9MAP2K72.72895186
10NTRK22.71541176
11FRK2.59828078
12MKNK22.20347838
13KSR12.13822573
14MAPK132.04064396
15PAK61.99724837
16TNIK1.97035658
17TRIM281.95930097
18MAP3K121.92702393
19PNCK1.89727810
20SIK21.87447914
21DAPK21.85183147
22MAP2K41.76726306
23PHKG11.64028358
24PHKG21.64028358
25ACVR1B1.59994977
26NTRK11.59350796
27CDK51.55260137
28NUAK11.54224178
29NEK11.54049456
30MAP4K21.52044180
31MKNK11.50198988
32UHMK11.45706723
33PLK41.44216627
34SIK31.35262792
35KSR21.33238304
36PLK21.31660472
37BUB11.26771129
38STK391.21229516
39CSNK1G21.21104077
40CDC71.19242806
41PLK31.18641267
42LATS21.17803557
43CAMKK11.15410390
44GRK51.14243456
45DYRK21.14065301
46TYRO31.13095215
47PRKD31.13042446
48INSRR1.12786963
49PRKCG1.10153269
50RIPK41.10004823
51BRSK21.09245099
52FES1.08567611
53CDK191.05373826
54DAPK11.04590009
55BCR1.02473699
56CDK181.02011174
57BRD41.01503144
58PINK11.00986692
59DYRK1A1.00765863
60TTK0.98870615
61PAK30.97699501
62CAMK2A0.96927759
63CDK140.95343802
64CDK150.94877789
65TGFBR10.94473044
66ERBB30.93582200
67WNK30.92735272
68SRPK10.91251036
69PBK0.84214668
70YES10.84090340
71CDK11A0.82391987
72CAMK1G0.79555995
73PLK10.79390458
74STK110.77295892
75MARK20.75874023
76RET0.75316146
77CSNK1G30.73957586
78PRPF4B0.73745832
79PKN10.72850541
80CAMK2B0.70560069
81SGK2230.69310992
82SGK4940.69310992
83OXSR10.69179805
84STK380.69033439
85EPHB20.68169564
86EIF2AK30.67474209
87ROCK10.65705563
88ZAK0.65440915
89MAP3K20.65399801
90PRKCZ0.62796886
91ATM0.62204473
92SGK10.60286608
93CAMK10.59612809
94STK38L0.58942519
95BRSK10.58554320
96EIF2AK20.58060816
97CAMKK20.57204184
98PRKCE0.54616689
99FYN0.54024775
100IRAK20.53541511
101FGFR20.53161544
102VRK10.53064780
103CDK30.52058408
104CSNK1A1L0.52009515
105FGR0.51968362
106WNK40.51700045
107PRKCH0.49279889
108SGK20.48253269
109GRK10.47671323
110ATR0.47505465
111RPS6KA20.45873556
112LIMK10.45648114
113CSNK1D0.45618579
114MAP3K60.45527678
115ARAF0.45037206
116CSNK1G10.44382730
117RPS6KA30.43644701
118BMPR20.42749566
119CCNB10.41886280
120TAF10.41826117
121CHEK20.41788590
122PRKDC0.41529719
123BMPR1B0.40776083
124PTK2B0.40704169
125ADRBK20.40668885
126ERBB20.40287578
127NME10.40114105
128CAMK2D0.38844550
129TAOK10.38649763
130FER0.38589382
131ROCK20.38431378
132ALK0.37248032
133LMTK20.36610192
134MAPK120.36535343
135MAPK100.36507598
136PRKG10.35673648
137CDC42BPA0.34804934
138PRKACA0.34542362
139AKT30.32889469
140MAP3K130.32652478
141ERBB40.32275918
142NEK20.32181445
143CSNK1A10.31867215
144MAPK90.31800613
145PRKCB0.30669371
146ICK0.29990022

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.89774145
2Non-homologous end-joining_Homo sapiens_hsa034503.28115856
3Synaptic vesicle cycle_Homo sapiens_hsa047213.18276449
4Fanconi anemia pathway_Homo sapiens_hsa034602.77980106
5GABAergic synapse_Homo sapiens_hsa047272.73550289
6Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.68249396
7Protein export_Homo sapiens_hsa030602.63395767
8Circadian entrainment_Homo sapiens_hsa047132.57015167
9Glutamatergic synapse_Homo sapiens_hsa047242.54618283
10Olfactory transduction_Homo sapiens_hsa047402.51264683
11Morphine addiction_Homo sapiens_hsa050322.49787398
12Long-term potentiation_Homo sapiens_hsa047202.35532803
13Amphetamine addiction_Homo sapiens_hsa050312.35485510
14Dopaminergic synapse_Homo sapiens_hsa047282.32197251
15Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.25779266
16Propanoate metabolism_Homo sapiens_hsa006402.07704288
17Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.04357037
18Cholinergic synapse_Homo sapiens_hsa047252.02046833
19Cocaine addiction_Homo sapiens_hsa050301.97520955
20Steroid biosynthesis_Homo sapiens_hsa001001.94555486
21Insulin secretion_Homo sapiens_hsa049111.91900043
22Salivary secretion_Homo sapiens_hsa049701.91706139
23Serotonergic synapse_Homo sapiens_hsa047261.90373421
24Homologous recombination_Homo sapiens_hsa034401.87353091
25Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.77736520
26Taste transduction_Homo sapiens_hsa047421.73016044
27Axon guidance_Homo sapiens_hsa043601.72921925
28Long-term depression_Homo sapiens_hsa047301.71146610
29Renin secretion_Homo sapiens_hsa049241.69359054
30Aldosterone synthesis and secretion_Homo sapiens_hsa049251.68415916
31Gastric acid secretion_Homo sapiens_hsa049711.63496251
32Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.62031524
33Basal transcription factors_Homo sapiens_hsa030221.59647890
34Gap junction_Homo sapiens_hsa045401.58189510
35Oxytocin signaling pathway_Homo sapiens_hsa049211.56296059
36Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.52346024
37Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.52078281
38Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.51601269
39Mismatch repair_Homo sapiens_hsa034301.49485359
40Calcium signaling pathway_Homo sapiens_hsa040201.47346555
41Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.42807946
42Collecting duct acid secretion_Homo sapiens_hsa049661.37831407
43GnRH signaling pathway_Homo sapiens_hsa049121.34052892
44Basal cell carcinoma_Homo sapiens_hsa052171.31239872
45Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.24470352
46Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.23819974
47cAMP signaling pathway_Homo sapiens_hsa040241.15544946
48Cell cycle_Homo sapiens_hsa041101.14963626
49Estrogen signaling pathway_Homo sapiens_hsa049151.14611330
50ErbB signaling pathway_Homo sapiens_hsa040121.13731386
51Glioma_Homo sapiens_hsa052141.13240916
52Type II diabetes mellitus_Homo sapiens_hsa049301.12629236
53Cardiac muscle contraction_Homo sapiens_hsa042601.12495074
54Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.12487499
55Nitrogen metabolism_Homo sapiens_hsa009101.08264375
56Melanogenesis_Homo sapiens_hsa049161.07939877
57Phototransduction_Homo sapiens_hsa047441.05210721
58Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.04531138
59beta-Alanine metabolism_Homo sapiens_hsa004101.02857515
60Fatty acid metabolism_Homo sapiens_hsa012121.00995848
61Base excision repair_Homo sapiens_hsa034100.98912096
62Lysine degradation_Homo sapiens_hsa003100.96684002
63Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.93278291
64cGMP-PKG signaling pathway_Homo sapiens_hsa040220.93055816
65Vibrio cholerae infection_Homo sapiens_hsa051100.92331465
66Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.88603468
67Oocyte meiosis_Homo sapiens_hsa041140.87127980
68Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.86302359
69Ether lipid metabolism_Homo sapiens_hsa005650.83368768
70Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.83266988
71Phospholipase D signaling pathway_Homo sapiens_hsa040720.82816978
72Phosphatidylinositol signaling system_Homo sapiens_hsa040700.82127328
73Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.80834809
74Vitamin B6 metabolism_Homo sapiens_hsa007500.79792422
75DNA replication_Homo sapiens_hsa030300.79230920
76RNA degradation_Homo sapiens_hsa030180.79109586
77Dilated cardiomyopathy_Homo sapiens_hsa054140.78519494
78Vascular smooth muscle contraction_Homo sapiens_hsa042700.77699397
79Dorso-ventral axis formation_Homo sapiens_hsa043200.76820078
80Fatty acid elongation_Homo sapiens_hsa000620.75372711
81Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.74291694
82Nucleotide excision repair_Homo sapiens_hsa034200.72972745
83Alcoholism_Homo sapiens_hsa050340.72460002
84MAPK signaling pathway_Homo sapiens_hsa040100.72402360
85Choline metabolism in cancer_Homo sapiens_hsa052310.72345493
86TGF-beta signaling pathway_Homo sapiens_hsa043500.71610804
87Wnt signaling pathway_Homo sapiens_hsa043100.67952656
88Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.67155592
89Ras signaling pathway_Homo sapiens_hsa040140.66687770
90Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.66511056
91Pancreatic secretion_Homo sapiens_hsa049720.64324156
92Fatty acid degradation_Homo sapiens_hsa000710.64072449
93Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.63823481
94Glycerolipid metabolism_Homo sapiens_hsa005610.63725246
95Endometrial cancer_Homo sapiens_hsa052130.63526203
96Renal cell carcinoma_Homo sapiens_hsa052110.63169712
97Thyroid hormone synthesis_Homo sapiens_hsa049180.61950331
98Sphingolipid signaling pathway_Homo sapiens_hsa040710.59924493
99Neurotrophin signaling pathway_Homo sapiens_hsa047220.59742207
100Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.58334039
101MicroRNAs in cancer_Homo sapiens_hsa052060.58015360
102Tryptophan metabolism_Homo sapiens_hsa003800.57977344
103Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.57874928
104Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.57340585
105Linoleic acid metabolism_Homo sapiens_hsa005910.57002966
106Alzheimers disease_Homo sapiens_hsa050100.56251788
107Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.54680174
108Colorectal cancer_Homo sapiens_hsa052100.54085911
109Rap1 signaling pathway_Homo sapiens_hsa040150.54081528
110RNA transport_Homo sapiens_hsa030130.53951742
111Circadian rhythm_Homo sapiens_hsa047100.53119201
112Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.53056246
113Thyroid hormone signaling pathway_Homo sapiens_hsa049190.52883969
114Prion diseases_Homo sapiens_hsa050200.52666750
115RNA polymerase_Homo sapiens_hsa030200.52513764
116VEGF signaling pathway_Homo sapiens_hsa043700.52270125
117Peroxisome_Homo sapiens_hsa041460.52184045
118Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.51455597
119Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.50867585
120Carbohydrate digestion and absorption_Homo sapiens_hsa049730.50696652
121Hedgehog signaling pathway_Homo sapiens_hsa043400.49634479
122Glucagon signaling pathway_Homo sapiens_hsa049220.49309210
123Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.49157348
124Type I diabetes mellitus_Homo sapiens_hsa049400.48677505
125alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.48147389
126mRNA surveillance pathway_Homo sapiens_hsa030150.47640320
127Pyruvate metabolism_Homo sapiens_hsa006200.46582054
128Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.43863884
129Histidine metabolism_Homo sapiens_hsa003400.43692870
130Endocytosis_Homo sapiens_hsa041440.43110922
131Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.42403044
132Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.41842507
133ABC transporters_Homo sapiens_hsa020100.41609512
134p53 signaling pathway_Homo sapiens_hsa041150.41117502
135Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.39835302
136Parkinsons disease_Homo sapiens_hsa050120.39760936
137Insulin signaling pathway_Homo sapiens_hsa049100.39046764
138Oxidative phosphorylation_Homo sapiens_hsa001900.38656404
139mTOR signaling pathway_Homo sapiens_hsa041500.38198490
140Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.37765561
141Regulation of autophagy_Homo sapiens_hsa041400.36735888
142Non-small cell lung cancer_Homo sapiens_hsa052230.35163546
143Longevity regulating pathway - mammal_Homo sapiens_hsa042110.35002490
144Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.33650695
145Butanoate metabolism_Homo sapiens_hsa006500.33630712
146Hippo signaling pathway_Homo sapiens_hsa043900.32474234
147African trypanosomiasis_Homo sapiens_hsa051430.32352527
148Ovarian steroidogenesis_Homo sapiens_hsa049130.31424368

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