SLC35F3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1daunorubicin metabolic process (GO:0044597)6.46188016
2polyketide metabolic process (GO:0030638)6.46188016
3doxorubicin metabolic process (GO:0044598)6.46188016
4regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.90066892
5vocalization behavior (GO:0071625)5.75260641
6positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.48901121
7locomotory exploration behavior (GO:0035641)5.37891698
8regulation of short-term neuronal synaptic plasticity (GO:0048172)5.37081075
9regulation of glutamate receptor signaling pathway (GO:1900449)5.33223985
10desmosome organization (GO:0002934)5.17696998
11synaptic vesicle docking involved in exocytosis (GO:0016081)5.05056368
12ionotropic glutamate receptor signaling pathway (GO:0035235)5.02728279
13aminoglycoside antibiotic metabolic process (GO:0030647)4.61212468
14neuronal action potential propagation (GO:0019227)4.50072142
15glutamate receptor signaling pathway (GO:0007215)4.46570236
16regulation of synaptic vesicle exocytosis (GO:2000300)4.46059356
17positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.40097346
18synaptic transmission, glutamatergic (GO:0035249)4.39134835
19synaptic vesicle exocytosis (GO:0016079)4.37315809
20regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.34718171
21cell-substrate junction assembly (GO:0007044)4.31843531
22neuron-neuron synaptic transmission (GO:0007270)4.30166937
23synaptic vesicle maturation (GO:0016188)4.28449658
24exploration behavior (GO:0035640)4.22980512
25bundle of His cell to Purkinje myocyte communication (GO:0086069)4.20993956
26protein localization to synapse (GO:0035418)4.20655364
27positive regulation of neurotransmitter secretion (GO:0001956)4.17807404
28negative regulation of keratinocyte proliferation (GO:0010839)4.15913917
29regulation of synaptic vesicle transport (GO:1902803)4.10626913
30regulation of long-term neuronal synaptic plasticity (GO:0048169)4.09456644
31neuron cell-cell adhesion (GO:0007158)4.05712961
32glutamate secretion (GO:0014047)4.00517833
33sodium ion export (GO:0071436)3.99144914
34synaptic vesicle endocytosis (GO:0048488)3.90691581
35regulation of neuronal synaptic plasticity (GO:0048168)3.89681900
36gamma-aminobutyric acid signaling pathway (GO:0007214)3.86661726
37positive regulation of neurotransmitter transport (GO:0051590)3.83871475
38negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.82994079
39neurotransmitter secretion (GO:0007269)3.81110166
40regulation of excitatory postsynaptic membrane potential (GO:0060079)3.78433771
41regulation of synapse structural plasticity (GO:0051823)3.70846997
42dendritic spine morphogenesis (GO:0060997)3.67549970
43positive regulation of membrane potential (GO:0045838)3.67198745
44response to histamine (GO:0034776)3.65845147
45long-term memory (GO:0007616)3.65586833
46neurotransmitter-gated ion channel clustering (GO:0072578)3.64694839
47G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.64097896
48regulation of postsynaptic membrane potential (GO:0060078)3.62355170
49regulation of synaptic transmission, glutamatergic (GO:0051966)3.60553793
50keratinocyte proliferation (GO:0043616)3.59811300
51gamma-aminobutyric acid transport (GO:0015812)3.55937814
52regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.49504455
53long-term synaptic potentiation (GO:0060291)3.44739862
54regulation of synaptic plasticity (GO:0048167)3.41592710
55positive regulation of synapse maturation (GO:0090129)3.37267771
56negative regulation of dendrite morphogenesis (GO:0050774)3.36224769
57cell adhesion mediated by integrin (GO:0033627)3.35613352
58negative regulation of synaptic transmission, GABAergic (GO:0032229)3.35421598
59neuron recognition (GO:0008038)3.34747456
60behavioral response to cocaine (GO:0048148)3.34725009
61cellular potassium ion homeostasis (GO:0030007)3.34608803
62transmission of nerve impulse (GO:0019226)3.32962435
63regulation of dendritic spine morphogenesis (GO:0061001)3.32615055
64presynaptic membrane assembly (GO:0097105)3.31302766
65membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.29649448
66proline transport (GO:0015824)3.28673257
67behavioral fear response (GO:0001662)3.27402335
68behavioral defense response (GO:0002209)3.27402335
69regulation of heart rate by cardiac conduction (GO:0086091)3.27205908
70postsynaptic membrane organization (GO:0001941)3.27016430
71neurotransmitter transport (GO:0006836)3.26506314
72regulation of neurotransmitter secretion (GO:0046928)3.24934302
73membrane hyperpolarization (GO:0060081)3.24045962
74auditory receptor cell differentiation (GO:0042491)3.20776611
75cytoskeletal anchoring at plasma membrane (GO:0007016)3.20350817
76neuron remodeling (GO:0016322)3.18655795
77potassium ion homeostasis (GO:0055075)3.16412773
78suckling behavior (GO:0001967)3.16251465
79dendritic spine organization (GO:0097061)3.15745277
80membrane depolarization (GO:0051899)3.15478249
81long term synaptic depression (GO:0060292)3.15104963
82positive regulation of synaptic transmission, GABAergic (GO:0032230)3.14998175
83regulation of keratinocyte proliferation (GO:0010837)3.11618636
84neuronal ion channel clustering (GO:0045161)3.11190226
85presynaptic membrane organization (GO:0097090)3.10997909
86cell communication involved in cardiac conduction (GO:0086065)3.10391118
87fear response (GO:0042596)3.10137437
88learning (GO:0007612)3.09077475
89regulation of neurotransmitter transport (GO:0051588)3.08976704
90membrane depolarization during action potential (GO:0086010)3.08548684
91intermediate filament organization (GO:0045109)3.08289033
92positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.07284352
93cerebellar Purkinje cell differentiation (GO:0021702)3.06576534
94negative regulation of macroautophagy (GO:0016242)3.05358489
95epithelial cell fate commitment (GO:0072148)3.05199638
96insulin secretion (GO:0030073)3.04532147
97positive regulation of synaptic transmission (GO:0050806)3.02713093
98peptidyl-tyrosine autophosphorylation (GO:0038083)3.02480899
99regulation of neurotransmitter levels (GO:0001505)3.02201506
100cerebellar Purkinje cell layer development (GO:0021680)3.01731328
101negative regulation of hormone biosynthetic process (GO:0032353)2.99978158
102auditory receptor cell stereocilium organization (GO:0060088)2.99410361
103regulation of synapse maturation (GO:0090128)2.98363522
104glandular epithelial cell differentiation (GO:0002067)2.98058385
105regulation of synaptic transmission (GO:0050804)2.97582494
106phosphorylated carbohydrate dephosphorylation (GO:0046838)2.95958210
107inositol phosphate dephosphorylation (GO:0046855)2.95958210
108glycine transport (GO:0015816)2.94934120
109positive regulation of insulin secretion involved in cellular response to glucose stimulus (GO:003572.93958893
110innervation (GO:0060384)2.93219137
111regulation of vesicle fusion (GO:0031338)2.92973807
112chemosensory behavior (GO:0007635)2.91213836
113vesicle transport along microtubule (GO:0047496)2.89811232
114intraspecies interaction between organisms (GO:0051703)2.89615295
115social behavior (GO:0035176)2.89615295
116layer formation in cerebral cortex (GO:0021819)2.89530490
117detection of calcium ion (GO:0005513)2.88811767
118axonal fasciculation (GO:0007413)2.88365297
119cerebellar granule cell differentiation (GO:0021707)2.88343225
120startle response (GO:0001964)2.87257888
121auditory behavior (GO:0031223)2.86194232
122cochlea development (GO:0090102)2.85848616
123regulation of dendritic spine development (GO:0060998)2.85491451
124synaptic transmission (GO:0007268)2.84820895
125regulation of type B pancreatic cell apoptotic process (GO:2000674)2.83532281
126glycosphingolipid biosynthetic process (GO:0006688)2.83444512
127keratinocyte development (GO:0003334)2.83325453
128G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.83313672
129inositol phosphate catabolic process (GO:0071545)2.80838129
130cardiac conduction (GO:0061337)2.77135601
131mating behavior (GO:0007617)2.72381507
132apical protein localization (GO:0045176)2.72061510
133regulation of hair follicle development (GO:0051797)2.70041120
134negative regulation of dendrite development (GO:2000171)2.66299428
135negative regulation of hormone metabolic process (GO:0032351)2.63002204
136glial cell proliferation (GO:0014009)2.59117204
137cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.54766828
138negative regulation of cytosolic calcium ion concentration (GO:0051481)2.52790575
139potassium ion import (GO:0010107)2.52336565
140positive regulation of neurological system process (GO:0031646)2.51066025
141negative regulation of activin receptor signaling pathway (GO:0032926)2.50251691
142regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.46571116
143cell communication by electrical coupling (GO:0010644)2.45930119
144glycerophospholipid catabolic process (GO:0046475)2.41481852
145positive regulation of synaptic transmission, dopaminergic (GO:0032226)2.41287624
146signal release (GO:0023061)2.39447106
147regulation of extracellular matrix disassembly (GO:0010715)2.38317860
148mesodermal cell differentiation (GO:0048333)2.37139507
149establishment of skin barrier (GO:0061436)2.35979149
150regulation of transforming growth factor beta1 production (GO:0032908)2.35592058
151regulation of transmission of nerve impulse (GO:0051969)2.34723556
152L-serine transport (GO:0015825)2.33994892
153magnesium ion transport (GO:0015693)2.32133686
154cardiac muscle cell action potential involved in contraction (GO:0086002)2.32112247
155regulation of transforming growth factor beta2 production (GO:0032909)2.31143993
156hemidesmosome assembly (GO:0031581)13.1600744

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TP63_17297297_ChIP-ChIP_HaCaT_Human9.65639029
2EZH2_22144423_ChIP-Seq_EOC_Human6.07596769
3GBX2_23144817_ChIP-Seq_PC3_Human3.87769026
4JARID2_20064375_ChIP-Seq_MESCs_Mouse3.23868063
5SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.17787805
6SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.12318689
7FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.02628842
8EZH2_18974828_ChIP-Seq_MESCs_Mouse2.82096066
9RNF2_18974828_ChIP-Seq_MESCs_Mouse2.82096066
10JARID2_20075857_ChIP-Seq_MESCs_Mouse2.74309947
11SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.70743202
12SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.68157048
13EED_16625203_ChIP-ChIP_MESCs_Mouse2.66165902
14EZH2_27304074_Chip-Seq_ESCs_Mouse2.58185736
15SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.54095175
16SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.51698243
17REST_21632747_ChIP-Seq_MESCs_Mouse2.47531332
18* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.40985067
19* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.35503107
20DROSHA_22980978_ChIP-Seq_HELA_Human2.32627778
21SUZ12_27294783_Chip-Seq_ESCs_Mouse2.26704832
22EZH2_27294783_Chip-Seq_ESCs_Mouse2.25586163
23RNF2_27304074_Chip-Seq_ESCs_Mouse2.18920293
24IKZF1_21737484_ChIP-ChIP_HCT116_Human2.11212661
25RARB_27405468_Chip-Seq_BRAIN_Mouse2.10269440
26GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.98960513
27TAF15_26573619_Chip-Seq_HEK293_Human1.87512562
28CTBP2_25329375_ChIP-Seq_LNCAP_Human1.85521060
29* REST_18959480_ChIP-ChIP_MESCs_Mouse1.79897869
30AR_21572438_ChIP-Seq_LNCaP_Human1.77513496
31GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.73954524
32CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.68831022
33PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.67854140
34ZFP57_27257070_Chip-Seq_ESCs_Mouse1.64069756
35* SMAD4_21799915_ChIP-Seq_A2780_Human1.63881821
36PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.63103958
37ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.62022195
38CTBP1_25329375_ChIP-Seq_LNCAP_Human1.61048057
39P300_19829295_ChIP-Seq_ESCs_Human1.61001796
40SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.57324840
41BMI1_23680149_ChIP-Seq_NPCS_Mouse1.54548218
42ERG_21242973_ChIP-ChIP_JURKAT_Human1.52618244
43RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.49895664
44EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.47484840
45* SMAD3_21741376_ChIP-Seq_EPCs_Human1.46388606
46CBX2_27304074_Chip-Seq_ESCs_Mouse1.42940785
47MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.39949101
48* SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.37984315
49SMAD_19615063_ChIP-ChIP_OVARY_Human1.36730154
50RING1B_27294783_Chip-Seq_ESCs_Mouse1.36152211
51TOP2B_26459242_ChIP-Seq_MCF-7_Human1.34485235
52TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.34029009
53AR_25329375_ChIP-Seq_VCAP_Human1.33594803
54PIAS1_25552417_ChIP-Seq_VCAP_Human1.33427707
55NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.31963680
56VDR_22108803_ChIP-Seq_LS180_Human1.31826411
57SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.24630929
58SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.24630929
59* EP300_21415370_ChIP-Seq_HL-1_Mouse1.22538883
60OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.21934161
61TCF4_18268006_ChIP-ChIP_LS174T_Human1.20941535
62STAT3_23295773_ChIP-Seq_U87_Human1.20824596
63NR3C1_23031785_ChIP-Seq_PC12_Mouse1.20302050
64RNF2_27304074_Chip-Seq_NSC_Mouse1.19825849
65POU3F2_20337985_ChIP-ChIP_501MEL_Human1.19448312
66MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.19409166
67* SOX2_21211035_ChIP-Seq_LN229_Gbm1.18228485
68CDX2_19796622_ChIP-Seq_MESCs_Mouse1.16515691
69TP63_23658742_ChIP-Seq_EP156T_Human1.16186307
70RXR_22108803_ChIP-Seq_LS180_Human1.15318194
71ZNF217_24962896_ChIP-Seq_MCF-7_Human1.13707821
72RING1B_27294783_Chip-Seq_NPCs_Mouse1.13321455
73HTT_18923047_ChIP-ChIP_STHdh_Human1.13063086
74TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.13046040
75AR_19668381_ChIP-Seq_PC3_Human1.12132792
76SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.12092955
77UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.11090168
78CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.10139363
79* RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.09996874
80* TCF4_23295773_ChIP-Seq_U87_Human1.09837435
81WT1_25993318_ChIP-Seq_PODOCYTE_Human1.08682404
82RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.08499760
83AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.08307013
84TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.08297301
85RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.08261425
86ZNF274_21170338_ChIP-Seq_K562_Hela1.07948076
87TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.07440934
88* ARNT_22903824_ChIP-Seq_MCF-7_Human1.07341660
89PRDM14_20953172_ChIP-Seq_ESCs_Human1.07323084
90RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.07018998
91CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.06954045
92* RUNX2_22187159_ChIP-Seq_PCA_Human1.06877333
93FUS_26573619_Chip-Seq_HEK293_Human1.05863763
94WT1_19549856_ChIP-ChIP_CCG9911_Human1.05172418
95AHR_22903824_ChIP-Seq_MCF-7_Human1.05050119
96PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.04708738
97IGF1R_20145208_ChIP-Seq_DFB_Human1.02982526
98TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.02897694
99TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.02882318
100POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.02882318
101MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.02139460
102TP53_16413492_ChIP-PET_HCT116_Human1.01871923
103NANOG_18555785_Chip-Seq_ESCs_Mouse1.01598444
104NR3C1_21868756_ChIP-Seq_MCF10A_Human0.99743461
105TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.99552869
106ER_23166858_ChIP-Seq_MCF-7_Human0.99272555
107JUN_21703547_ChIP-Seq_K562_Human0.98438010
108TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.98158713
109* YAP1_20516196_ChIP-Seq_MESCs_Mouse0.98104907
110CMYC_18555785_Chip-Seq_ESCs_Mouse0.97740804
111* CJUN_26792858_Chip-Seq_BT549_Human0.95687639
112* TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.95682299
113ZNF263_19887448_ChIP-Seq_K562_Human0.95591336
114BCAT_22108803_ChIP-Seq_LS180_Human0.95107620
115TP53_18474530_ChIP-ChIP_U2OS_Human0.94750446
116* TET1_21490601_ChIP-Seq_MESCs_Mouse0.94574792
117E2F1_18555785_Chip-Seq_ESCs_Mouse0.94162211
118* KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse0.94116267
119* SMAD4_21741376_ChIP-Seq_HESCs_Human0.94032625
120* SMAD3_21741376_ChIP-Seq_HESCs_Human0.93824376
121SOX9_24532713_ChIP-Seq_HFSC_Mouse0.93515205
122EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.92243201
123SMAD3_21741376_ChIP-Seq_ESCs_Human0.91754625
124* P53_22127205_ChIP-Seq_FIBROBLAST_Human0.91458482
125DNAJC2_21179169_ChIP-ChIP_NT2_Human0.90361453
126ELK4_26923725_Chip-Seq_MESODERM_Mouse0.90290026
127SOX2_18555785_Chip-Seq_ESCs_Mouse0.88506259
128LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.88121414
129TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.87935046
130TRIM28_21343339_ChIP-Seq_HEK293_Human0.87806897
131P53_22387025_ChIP-Seq_ESCs_Mouse0.87171241

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0000579_abnormal_nail_morphology6.93735084
2MP0004859_abnormal_synaptic_plasticity5.91925670
3MP0003880_abnormal_central_pattern5.20722433
4MP0003635_abnormal_synaptic_transmissio3.90614379
5MP0009745_abnormal_behavioral_response3.47376191
6MP0010234_abnormal_vibrissa_follicle3.20546212
7MP0002063_abnormal_learning/memory/cond3.09569622
8MP0009046_muscle_twitch3.09367062
9MP0001968_abnormal_touch/_nociception3.04471725
10MP0002064_seizures3.03043642
11MP0005423_abnormal_somatic_nervous3.02012754
12MP0004270_analgesia2.95419793
13MP0002572_abnormal_emotion/affect_behav2.90531955
14MP0001486_abnormal_startle_reflex2.74224703
15MP0002822_catalepsy2.64200402
16MP0002272_abnormal_nervous_system2.60644857
17MP0003879_abnormal_hair_cell2.50709692
18MP0002736_abnormal_nociception_after2.43341590
19MP0002735_abnormal_chemical_nociception2.42652109
20MP0005377_hearing/vestibular/ear_phenot2.35091194
21MP0003878_abnormal_ear_physiology2.35091194
22MP0001501_abnormal_sleep_pattern2.35052914
23MP0001440_abnormal_grooming_behavior2.34973919
24MP0002734_abnormal_mechanical_nocicepti2.28901432
25MP0000762_abnormal_tongue_morphology2.25942197
26MP0010678_abnormal_skin_adnexa2.24253486
27MP0005645_abnormal_hypothalamus_physiol2.16583471
28MP0006276_abnormal_autonomic_nervous2.09775096
29MP0002067_abnormal_sensory_capabilities2.00991008
30MP0008004_abnormal_stomach_pH1.95020339
31MP0000383_abnormal_hair_follicle1.91977061
32MP0004924_abnormal_behavior1.90618812
33MP0005386_behavior/neurological_phenoty1.90618812
34MP0005646_abnormal_pituitary_gland1.87244710
35MP0005379_endocrine/exocrine_gland_phen1.85261813
36MP0002184_abnormal_innervation1.84689872
37MP0002557_abnormal_social/conspecific_i1.82730553
38MP0001970_abnormal_pain_threshold1.81304446
39MP0002733_abnormal_thermal_nociception1.74678213
40MP0000013_abnormal_adipose_tissue1.73432547
41MP0000467_abnormal_esophagus_morphology1.73267688
42MP0004885_abnormal_endolymph1.70549554
43MP0004272_abnormal_basement_membrane1.69931417
44MP0003123_paternal_imprinting1.69184195
45MP0001849_ear_inflammation1.66830894
46MP0001529_abnormal_vocalization1.66630060
47MP0000778_abnormal_nervous_system1.64446959
48MP0002060_abnormal_skin_morphology1.61509840
49MP0008569_lethality_at_weaning1.57588569
50MP0004742_abnormal_vestibular_system1.54741486
51MP0001485_abnormal_pinna_reflex1.54059698
52MP0004858_abnormal_nervous_system1.52988513
53MP0003283_abnormal_digestive_organ1.51551761
54MP0001944_abnormal_pancreas_morphology1.50672330
55MP0000566_synostosis1.48014465
56MP0000427_abnormal_hair_cycle1.44559382
57MP0004811_abnormal_neuron_physiology1.43320815
58MP0000678_abnormal_parathyroid_gland1.34420055
59MP0001216_abnormal_epidermal_layer1.33404530
60MP0002066_abnormal_motor_capabilities/c1.32800952
61MP0000569_abnormal_digit_pigmentation1.32183205
62MP0009780_abnormal_chondrocyte_physiolo1.30845430
63MP0006292_abnormal_olfactory_placode1.30333377
64MP0001984_abnormal_olfaction1.25946042
65MP0004142_abnormal_muscle_tone1.25911272
66MP0010771_integument_phenotype1.21469331
67MP0000955_abnormal_spinal_cord1.20728492
68MP0001188_hyperpigmentation1.20679495
69MP0008872_abnormal_physiological_respon1.19330660
70MP0003329_amyloid_beta_deposits1.18475842
71MP0001905_abnormal_dopamine_level1.15978051
72MP0008874_decreased_physiological_sensi1.14946964
73MP0002882_abnormal_neuron_morphology1.14748772
74MP0002909_abnormal_adrenal_gland1.14658291
75MP0003941_abnormal_skin_development1.14318370
76MP0003045_fibrosis1.13748274
77MP0003566_abnormal_cell_adhesion1.12266487
78MP0000377_abnormal_hair_follicle1.10714470
79MP0003633_abnormal_nervous_system1.09118657
80MP0001963_abnormal_hearing_physiology1.07103202
81MP0001502_abnormal_circadian_rhythm1.07088978
82MP0001299_abnormal_eye_distance/1.06017855
83MP0004019_abnormal_vitamin_homeostasis1.05247623
84MP0001177_atelectasis1.01184478
85MP0003890_abnormal_embryonic-extraembry0.97072374
86MP0000462_abnormal_digestive_system0.96259203
87MP0001664_abnormal_digestion0.95035808
88MP0004381_abnormal_hair_follicle0.93059526
89MP0003453_abnormal_keratinocyte_physiol0.93003399
90MP0002069_abnormal_eating/drinking_beha0.92286420
91MP0003787_abnormal_imprinting0.91161329
92MP0000537_abnormal_urethra_morphology0.91069974
93MP0008789_abnormal_olfactory_epithelium0.91036986
94MP0000538_abnormal_urinary_bladder0.90796838
95MP0010386_abnormal_urinary_bladder0.89328419
96MP0003121_genomic_imprinting0.88985370
97MP0002152_abnormal_brain_morphology0.88572551
98MP0002098_abnormal_vibrissa_morphology0.88498649
99MP0003631_nervous_system_phenotype0.87215069
100MP0006072_abnormal_retinal_apoptosis0.87200155
101MP0000003_abnormal_adipose_tissue0.86872532
102MP0004085_abnormal_heartbeat0.86425262
103MP0002693_abnormal_pancreas_physiology0.83627421
104MP0000631_abnormal_neuroendocrine_gland0.83308320
105MP0003646_muscle_fatigue0.82834251
106MP0002837_dystrophic_cardiac_calcinosis0.82449471
107MP0005275_abnormal_skin_tensile0.80576174
108MP0002295_abnormal_pulmonary_circulatio0.80054174
109MP0002796_impaired_skin_barrier0.79689234
110MP0002229_neurodegeneration0.79257738
111MP0005257_abnormal_intraocular_pressure0.77723302
112MP0005623_abnormal_meninges_morphology0.75660499
113MP0002177_abnormal_outer_ear0.75450061
114MP0005501_abnormal_skin_physiology0.74504984
115MP0004043_abnormal_pH_regulation0.74217062
116MP0005171_absent_coat_pigmentation0.73939497
117MP0004145_abnormal_muscle_electrophysio0.72431323
118MP0004133_heterotaxia0.71910185
119MP0003315_abnormal_perineum_morphology0.71680620
120MP0004484_altered_response_of0.70237687
121MP0003122_maternal_imprinting0.69990069
122MP0003075_altered_response_to0.69975768
123MP0002090_abnormal_vision0.69522731
124MP0000026_abnormal_inner_ear0.68851736
125MP0005394_taste/olfaction_phenotype0.68625584
126MP0005499_abnormal_olfactory_system0.68625584
127MP0002928_abnormal_bile_duct0.68483357
128MP0000647_abnormal_sebaceous_gland0.67666641
129MP0001986_abnormal_taste_sensitivity0.67619598
130MP0002752_abnormal_somatic_nervous0.66572699
131MP0001765_abnormal_ion_homeostasis0.65783909
132MP0005535_abnormal_body_temperature0.63667571
133MP0005551_abnormal_eye_electrophysiolog0.60539446
134MP0002876_abnormal_thyroid_physiology0.59655417
135MP0003634_abnormal_glial_cell0.59391306
136MP0005409_darkened_coat_color0.58880901
137MP0005167_abnormal_blood-brain_barrier0.58325786
138MP0003690_abnormal_glial_cell0.58163794
139MP0002163_abnormal_gland_morphology0.56728257
140MP0000920_abnormal_myelination0.56394333
141MP0002102_abnormal_ear_morphology0.54612277
142MP0004215_abnormal_myocardial_fiber0.53031269
143MP0000681_abnormal_thyroid_gland0.52184656
144MP0003632_abnormal_nervous_system0.51009521
145MP0002234_abnormal_pharynx_morphology0.50732623
146MP0004233_abnormal_muscle_weight0.49125793
147MP0000751_myopathy0.47382092
148MP0003938_abnormal_ear_development0.46784105
149MP0010769_abnormal_survival0.46692231

Predicted human phenotypes

RankGene SetZ-score
1Milia (HP:0001056)8.26981634
2Focal motor seizures (HP:0011153)8.17488292
3Onycholysis (HP:0001806)7.60083997
4Fragile nails (HP:0001808)7.54223978
5Atrophic scars (HP:0001075)7.50515825
6Plantar hyperkeratosis (HP:0007556)6.42225119
7Myokymia (HP:0002411)6.18742597
8Focal seizures (HP:0007359)5.45528838
9Abnormality of nail color (HP:0100643)4.87436499
10Epileptic encephalopathy (HP:0200134)4.83869414
11Atonic seizures (HP:0010819)4.75639059
12Febrile seizures (HP:0002373)4.68391424
13Parakeratosis (HP:0001036)4.64456668
14Visual hallucinations (HP:0002367)4.48512565
15Hypoplasia of dental enamel (HP:0006297)4.26003543
16Hyperventilation (HP:0002883)4.22568316
17Nail dystrophy (HP:0008404)4.11938269
18Unilateral renal agenesis (HP:0000122)4.00243184
19Absence seizures (HP:0002121)3.95430580
20Thick nail (HP:0001805)3.94176391
21Progressive cerebellar ataxia (HP:0002073)3.77014435
22Broad-based gait (HP:0002136)3.72307978
23Dynein arm defect of respiratory motile cilia (HP:0012255)3.70630965
24Absent/shortened dynein arms (HP:0200106)3.70630965
25Palmoplantar hyperkeratosis (HP:0000972)3.70112207
26Poor eye contact (HP:0000817)3.64022010
27Dialeptic seizures (HP:0011146)3.63089704
28Generalized tonic-clonic seizures (HP:0002069)3.59001396
29Absent eyebrow (HP:0002223)3.52134118
30Abnormality of dental color (HP:0011073)3.50024272
31Ridged nail (HP:0001807)3.45229179
32Palmar hyperkeratosis (HP:0010765)3.44446987
33Action tremor (HP:0002345)3.41343473
34Pili torti (HP:0003777)3.30048477
35Alopecia of scalp (HP:0002293)3.28812390
36Abnormal social behavior (HP:0012433)3.23627722
37Impaired social interactions (HP:0000735)3.23627722
38Right ventricular cardiomyopathy (HP:0011663)3.20772886
39Follicular hyperkeratosis (HP:0007502)3.18596195
40Aplasia cutis congenita (HP:0001057)3.08825946
41Fragile skin (HP:0001030)3.07927935
42Supranuclear gaze palsy (HP:0000605)3.07080268
43Abnormal blistering of the skin (HP:0008066)3.04732951
44Gaze-evoked nystagmus (HP:0000640)3.03848294
45Bilateral sensorineural hearing impairment (HP:0008619)2.90219085
46Amblyopia (HP:0000646)2.84500917
47Pterygium (HP:0001059)2.82485154
48Impaired vibration sensation in the lower limbs (HP:0002166)2.78784808
49Absent eyelashes (HP:0000561)2.72468977
50Fetal akinesia sequence (HP:0001989)2.66848200
51Drooling (HP:0002307)2.66232157
52Excessive salivation (HP:0003781)2.66232157
53Anxiety (HP:0000739)2.65187785
54Postural instability (HP:0002172)2.65017882
55Absent speech (HP:0001344)2.63212625
56Hypoplastic labia majora (HP:0000059)2.56028946
57Recurrent corneal erosions (HP:0000495)2.55327961
58Truncal ataxia (HP:0002078)2.54715026
59Dysmetria (HP:0001310)2.54433532
60Abnormality of binocular vision (HP:0011514)2.52975683
61Diplopia (HP:0000651)2.52975683
62Hypodontia (HP:0000668)2.50232654
63Abnormal eating behavior (HP:0100738)2.50112562
64Esophageal atresia (HP:0002032)2.45698658
65Scanning speech (HP:0002168)2.42738118
66Dysdiadochokinesis (HP:0002075)2.42437397
67Hyperactive renin-angiotensin system (HP:0000841)2.41309086
68Sparse scalp hair (HP:0002209)2.39157305
69Abnormal ciliary motility (HP:0012262)2.36686737
70Depression (HP:0000716)2.33694105
71Amelogenesis imperfecta (HP:0000705)2.29758690
72Urinary bladder sphincter dysfunction (HP:0002839)2.29513557
73Hyperphosphatemia (HP:0002905)2.25192979
74Hemiparesis (HP:0001269)2.24695219
75Abnormality of the labia majora (HP:0012881)2.23852215
76Metabolic alkalosis (HP:0200114)2.21389498
77Inability to walk (HP:0002540)2.20451453
78Stereotypic behavior (HP:0000733)2.20025276
79Impaired smooth pursuit (HP:0007772)2.19384997
80Woolly hair (HP:0002224)2.18852500
81Abnormal hair laboratory examination (HP:0003328)2.17316533
82Epileptiform EEG discharges (HP:0011182)2.17311543
83Progressive inability to walk (HP:0002505)2.17109952
84Absent hair (HP:0002298)2.16633181
85Gastrointestinal atresia (HP:0002589)2.16070372
86Global brain atrophy (HP:0002283)2.12744741
87Cerebral inclusion bodies (HP:0100314)2.11259102
88Ankle clonus (HP:0011448)2.11009710
89Elevated circulating parathyroid hormone (PTH) level (HP:0003165)2.09594323
90Limb dystonia (HP:0002451)2.08753139
91Urinary urgency (HP:0000012)2.03073016
92Abnormal respiratory motile cilium morphology (HP:0005938)2.02409908
93Abnormal respiratory epithelium morphology (HP:0012253)2.02409908
94Blue irides (HP:0000635)1.98510898
95Status epilepticus (HP:0002133)1.98397350
96EEG with generalized epileptiform discharges (HP:0011198)1.97948026
97Labial hypoplasia (HP:0000066)1.93751450
98Vascular calcification (HP:0004934)1.92619360
99Postural tremor (HP:0002174)1.92595966
100Widely spaced teeth (HP:0000687)1.91935420
101Sensory axonal neuropathy (HP:0003390)1.91932743
102Hemiplegia (HP:0002301)1.91381329
103Hyperaldosteronism (HP:0000859)1.91274894
104Obstructive sleep apnea (HP:0002870)1.90880912
105Intention tremor (HP:0002080)1.90749279
106Neurofibrillary tangles (HP:0002185)1.90747283
107Bradykinesia (HP:0002067)1.90687059
108Incomplete penetrance (HP:0003829)1.89999128
109Increased circulating renin level (HP:0000848)1.89539250
110Genetic anticipation (HP:0003743)1.89268851
111Torticollis (HP:0000473)1.89189047
112Tetany (HP:0001281)1.88940135
113Protruding tongue (HP:0010808)1.88056359
114Abnormal respiratory motile cilium physiology (HP:0012261)1.87175905
115Abnormality of salivation (HP:0100755)1.86641071
116Autism (HP:0000717)1.84371749
117Hyperglycemia (HP:0003074)1.83494526
118Abnormality of the neuromuscular junction (HP:0003398)1.82772124
119Fatigable weakness (HP:0003473)1.82772124
120Urethral obstruction (HP:0000796)1.82639354
121Dry hair (HP:0011359)1.82174222
122Dysmetric saccades (HP:0000641)1.81340810
123Congenital malformation of the right heart (HP:0011723)1.80964216
124Double outlet right ventricle (HP:0001719)1.80964216
125Spastic gait (HP:0002064)1.80786329
126Carious teeth (HP:0000670)1.80712516
127Gait ataxia (HP:0002066)1.79629192
128Hypsarrhythmia (HP:0002521)1.78712732
129Abnormality of calcium-phosphate metabolism (HP:0100530)1.77858510
130Mutism (HP:0002300)1.77466242
131Anonychia (HP:0001798)1.77160315
132Advanced eruption of teeth (HP:0006288)1.76911701
133Laryngomalacia (HP:0001601)1.76870609
134Abnormality of ocular smooth pursuit (HP:0000617)1.76743144
135Hypotrichosis (HP:0001006)1.76402666
136Annular pancreas (HP:0001734)1.76080706
137Sparse eyelashes (HP:0000653)1.75757059
138Natal tooth (HP:0000695)1.75347748
139Abnormality of renin-angiotensin system (HP:0000847)1.75084836
140Fair hair (HP:0002286)1.74241687
141Abnormality of aromatic amino acid family metabolism (HP:0004338)1.73610614
142Focal dystonia (HP:0004373)1.73373425
143Vertebral arch anomaly (HP:0008438)1.72315476
144Insidious onset (HP:0003587)1.71252210
145Termporal pattern (HP:0011008)1.71252210
146Hypoplastic female external genitalia (HP:0012815)1.70947030
147Abnormality of the corticospinal tract (HP:0002492)1.70535439
148Generalized hypopigmentation of hair (HP:0011358)1.69898088
149Abnormality of the lower motor neuron (HP:0002366)1.69609123
150Autoamputation (HP:0001218)1.69147039
151Hypoglycemic seizures (HP:0002173)1.67337152
152Selective tooth agenesis (HP:0001592)1.66593898
153Generalized myoclonic seizures (HP:0002123)1.65451086
154Abnormality of chloride homeostasis (HP:0011422)1.64865109
155Hyperhidrosis (HP:0000975)1.64519037
156Aqueductal stenosis (HP:0002410)1.63740908
157Overlapping toe (HP:0001845)1.63414113
158Agitation (HP:0000713)1.61831115
159Ankyloglossia (HP:0010296)1.61662027
160Hypokinesia (HP:0002375)1.61355202
161Oligodactyly (hands) (HP:0001180)1.58072089
162Abnormality of permanent molar morphology (HP:0011071)1.57738601
163Abnormality of the dental root (HP:0006486)1.57738601
164Taurodontia (HP:0000679)1.57738601
165Hoarse voice (HP:0001609)1.57281690
166Akinesia (HP:0002304)1.54267467
167Syncope (HP:0001279)1.53186147
168Death in infancy (HP:0001522)1.52822815
169Diminished movement (HP:0002374)1.52665483
170Cardiovascular calcification (HP:0011915)1.50994491

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NTRK35.02792157
2EPHA44.80666863
3SIK33.47631298
4SIK23.01449933
5MAP3K122.76108004
6MAP3K92.71180040
7CASK2.61452373
8MAP3K42.60131957
9RIPK42.58652023
10MAP2K72.33128607
11MST1R2.25965559
12MINK12.16639065
13DAPK21.89820845
14MARK11.88690137
15MAP2K41.87624560
16TNIK1.84302298
17NTRK21.80717185
18PNCK1.68493024
19PRPF4B1.68363781
20PAK61.59483734
21NTRK11.56724225
22LMTK21.56085408
23FGFR21.53253739
24FRK1.52017153
25MET1.51369592
26STK381.49700737
27KSR21.46961402
28PLK21.46847285
29GRK51.44027150
30PIM21.37801503
31CAMKK11.37494964
32DAPK11.35690359
33PTK21.33910712
34EPHB21.33670717
35MAPK131.33501229
36EPHA21.29373357
37CDK51.26974312
38FES1.25721627
39KSR11.24869161
40MST41.21901252
41SIK11.18511096
42BMPR21.17722735
43PRKD31.16110238
44PRKCG1.13846341
45CDK191.12497531
46ROCK21.10990325
47OXSR11.10845376
48MAP3K131.08929132
49TRPM71.07149882
50CAMK11.06128741
51LATS21.05361634
52CAMK2A1.03632864
53MOS1.03554124
54RIPK11.02978295
55SGK21.02900074
56CAMKK21.01444816
57ARAF1.01312390
58SGK4941.00906038
59SGK2231.00906038
60MAP3K20.99474633
61FGR0.95546101
62PTK2B0.93268478
63WNK10.92231007
64MARK20.89086505
65CAMK2B0.87608002
66ADRBK20.84619295
67TESK10.82919646
68DYRK1A0.78010436
69SGK10.77372910
70STK110.74973575
71SGK30.73390594
72UHMK10.70279538
73PRKCI0.69554030
74TRIM280.67974731
75TNK20.67297465
76ERBB30.65268500
77MARK30.61389470
78CDK180.58349932
79NME10.58208678
80PRKCE0.57671278
81CAMK1G0.57215295
82STK240.56352969
83CDK150.55939262
84FER0.55407744
85PINK10.54611284
86CAMK40.54213714
87TYRO30.54140959
88CDK140.52833632
89PAK30.51003312
90LIMK10.50659353
91PHKG20.50430775
92PHKG10.50430775
93RPS6KA20.50024423
94PRKCH0.49571576
95MUSK0.49519452
96CDK30.48256979
97RAF10.47783009
98MAP2K10.46756695
99AKT30.46649345
100CAMK2G0.46596871
101MAP3K10.45337606
102CDK11A0.45115722
103CSNK1G30.44674815
104CCNB10.44329217
105EPHB10.43548983
106BMPR1B0.42744460
107GRK70.42417816
108BRD40.42390526
109CAMK2D0.42276091
110ACVR1B0.42034673
111YES10.41770128
112CSNK1G20.40190596
113TAOK10.39968345
114PDPK10.39836614
115PDK10.39558248
116CSNK1G10.39496143
117FYN0.39457587
118RPS6KA30.39017089
119PRKG10.37066683
120CSNK1A10.36737733
121NEK60.35923132
122RET0.35181127
123WNK30.35171443
124MAPK100.34117235
125PRKACA0.33852296
126BRAF0.32561123
127BMX0.32530773
128PRKCA0.32502630
129ALK0.32232259
130AKT20.31681295
131PRKCZ0.30168418
132CAMK1D0.29470990
133ROCK10.29073485
134RPS6KB10.28666633
135STK30.27738399

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.30647058
2Synaptic vesicle cycle_Homo sapiens_hsa047213.14396660
3Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.87128849
4Long-term potentiation_Homo sapiens_hsa047202.73133521
5Circadian entrainment_Homo sapiens_hsa047132.72592301
6GABAergic synapse_Homo sapiens_hsa047272.68973675
7Glutamatergic synapse_Homo sapiens_hsa047242.66455001
8Morphine addiction_Homo sapiens_hsa050322.63305420
9Olfactory transduction_Homo sapiens_hsa047402.60457952
10Amphetamine addiction_Homo sapiens_hsa050312.49882003
11Salivary secretion_Homo sapiens_hsa049702.27782335
12Maturity onset diabetes of the young_Homo sapiens_hsa049502.22696651
13Taste transduction_Homo sapiens_hsa047422.22395598
14Dopaminergic synapse_Homo sapiens_hsa047282.09620955
15Gastric acid secretion_Homo sapiens_hsa049712.05784493
16Calcium signaling pathway_Homo sapiens_hsa040201.94358706
17Serotonergic synapse_Homo sapiens_hsa047261.91698567
18Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.90831319
19Renin secretion_Homo sapiens_hsa049241.88220310
20Insulin secretion_Homo sapiens_hsa049111.86625894
21Long-term depression_Homo sapiens_hsa047301.85255858
22ECM-receptor interaction_Homo sapiens_hsa045121.79824593
23Aldosterone synthesis and secretion_Homo sapiens_hsa049251.78052996
24Cholinergic synapse_Homo sapiens_hsa047251.77270786
25Collecting duct acid secretion_Homo sapiens_hsa049661.69846042
26Oxytocin signaling pathway_Homo sapiens_hsa049211.62132315
27Vitamin B6 metabolism_Homo sapiens_hsa007501.58693838
28Cocaine addiction_Homo sapiens_hsa050301.56086187
29Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.52723191
30Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.48680247
31Sphingolipid metabolism_Homo sapiens_hsa006001.41390909
32Protein export_Homo sapiens_hsa030601.41387465
33GnRH signaling pathway_Homo sapiens_hsa049121.40610051
34Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.37607943
35Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.35431747
36Axon guidance_Homo sapiens_hsa043601.34851189
37cAMP signaling pathway_Homo sapiens_hsa040241.33206644
38Phosphatidylinositol signaling system_Homo sapiens_hsa040701.28942018
39Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.26144640
40Gap junction_Homo sapiens_hsa045401.22502476
41Cardiac muscle contraction_Homo sapiens_hsa042601.10521801
42Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.06884798
43Type II diabetes mellitus_Homo sapiens_hsa049301.06286645
44Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.05881043
45cGMP-PKG signaling pathway_Homo sapiens_hsa040221.01177625
46Estrogen signaling pathway_Homo sapiens_hsa049150.99280988
47ErbB signaling pathway_Homo sapiens_hsa040120.98446561
48Pancreatic secretion_Homo sapiens_hsa049720.96315299
49Glioma_Homo sapiens_hsa052140.94583169
50Vascular smooth muscle contraction_Homo sapiens_hsa042700.91930076
51Melanogenesis_Homo sapiens_hsa049160.91914841
52Mineral absorption_Homo sapiens_hsa049780.91569237
53Vibrio cholerae infection_Homo sapiens_hsa051100.91383906
54Folate biosynthesis_Homo sapiens_hsa007900.91370523
55Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.87994365
56Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.87026509
57Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.86036448
58Focal adhesion_Homo sapiens_hsa045100.85388057
59Hippo signaling pathway_Homo sapiens_hsa043900.82361934
60Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.82216458
61Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.81769435
62Phototransduction_Homo sapiens_hsa047440.78245181
63N-Glycan biosynthesis_Homo sapiens_hsa005100.77973283
64Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.77083527
65Alzheimers disease_Homo sapiens_hsa050100.76874867
66Small cell lung cancer_Homo sapiens_hsa052220.75798612
67Steroid biosynthesis_Homo sapiens_hsa001000.75395183
68Oxidative phosphorylation_Homo sapiens_hsa001900.73490414
69Choline metabolism in cancer_Homo sapiens_hsa052310.71419227
70African trypanosomiasis_Homo sapiens_hsa051430.71349406
71Phospholipase D signaling pathway_Homo sapiens_hsa040720.70779630
72Thyroid hormone synthesis_Homo sapiens_hsa049180.70619358
73Dilated cardiomyopathy_Homo sapiens_hsa054140.67153852
74MAPK signaling pathway_Homo sapiens_hsa040100.67105114
75Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.66422009
76Ras signaling pathway_Homo sapiens_hsa040140.61532386
77Dorso-ventral axis formation_Homo sapiens_hsa043200.60531304
78Amoebiasis_Homo sapiens_hsa051460.59979565
79Sulfur metabolism_Homo sapiens_hsa009200.58696271
80Ovarian steroidogenesis_Homo sapiens_hsa049130.58658760
81Fatty acid elongation_Homo sapiens_hsa000620.58087969
82Butanoate metabolism_Homo sapiens_hsa006500.57679110
83Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.57419588
84Central carbon metabolism in cancer_Homo sapiens_hsa052300.57205878
85Rap1 signaling pathway_Homo sapiens_hsa040150.56973406
86Protein digestion and absorption_Homo sapiens_hsa049740.54818014
87Oocyte meiosis_Homo sapiens_hsa041140.53154694
88Tight junction_Homo sapiens_hsa045300.52817616
89Proteoglycans in cancer_Homo sapiens_hsa052050.52458910
90Carbohydrate digestion and absorption_Homo sapiens_hsa049730.52442060
91Glucagon signaling pathway_Homo sapiens_hsa049220.51701223
92Bile secretion_Homo sapiens_hsa049760.50408903
93Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.50363055
94Inositol phosphate metabolism_Homo sapiens_hsa005620.48278333
95Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.47881470
96Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.46980615
97Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.46838909
98Parkinsons disease_Homo sapiens_hsa050120.46734576
99Circadian rhythm_Homo sapiens_hsa047100.46447429
100Endometrial cancer_Homo sapiens_hsa052130.45446790
101Wnt signaling pathway_Homo sapiens_hsa043100.45234702
102Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.44864990
103Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.44411080
104Adherens junction_Homo sapiens_hsa045200.43010734
105Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.42985209
106VEGF signaling pathway_Homo sapiens_hsa043700.42830782
107Renal cell carcinoma_Homo sapiens_hsa052110.40779950
108SNARE interactions in vesicular transport_Homo sapiens_hsa041300.40289632
109Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.39006676
110Sphingolipid signaling pathway_Homo sapiens_hsa040710.38973142
111Rheumatoid arthritis_Homo sapiens_hsa053230.35964797
112Neurotrophin signaling pathway_Homo sapiens_hsa047220.33319611
113Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.32631635
114Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.30642629
115Type I diabetes mellitus_Homo sapiens_hsa049400.30581196
116Huntingtons disease_Homo sapiens_hsa050160.28886549
117Melanoma_Homo sapiens_hsa052180.28841957
118Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.28825855
119Alcoholism_Homo sapiens_hsa050340.27702564
120Regulation of actin cytoskeleton_Homo sapiens_hsa048100.26392896
121Thyroid hormone signaling pathway_Homo sapiens_hsa049190.21425589
122Prion diseases_Homo sapiens_hsa050200.20842592
123Endocytosis_Homo sapiens_hsa041440.19724272
124Chemokine signaling pathway_Homo sapiens_hsa040620.19089393
125Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.18829980
126Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.18742624
127Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.17863402

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